The structure of methyl 3-(trimethylammonium)benzoate iodide, 3-(Me)3N+C6H4CO2MeI−, (1a) has been determined by X-ray diffraction, DFT calculations and characterized by FTIR and NMR spectroscopy. The crystals are orthorhombic, space group Pnma and the structure is stabilized by interaction of I ...

Spectroscopic steady state studies of four monosubstituted derivatives of methyl benzoate dissolved in methylcyclohexane (McH), tetrahydrofuran (THF), ethanol (EtOH) and isopentane–diethyl ether mixture (IP–DE) have been performed at 293 and 77 K. The determined electronic energy values and os...

Steady-state and time-resolved spectroscopic studies of two bisubstituted derivatives of methyl benzoate dissolved in methylcyclohexane (McH), tetrahydrofuran (THF), and ethanol (EtOH) have been performed at 293 and 77 K. The compounds under study are capable of showing multimode fluorescence em...

The structure of methyl 4-(trimethylammonium)benzoate iodide, 4-(Me)3N+C6H4CO2MeI−, (1a) has been determined by X-ray diffraction, DFT calculations and characterized by FTIR and NMR spectroscopy. The crystals are triclinic, space group P1¯. The electrostatic distances N+⋯I− vary between 4.423(3...

Posttranslational modification of histones by biotinylation can be catalyzed by both biotinidase (BTD) and holocarboxylase synthetase. Biotinylation of histones is an important epigenetic mechanism to regulate gene expression, DNA repair, and chromatin remodeling. The role of BTD in histone biot...

Chromium-containing ethane-bridged hybrid mesoporous materials (Cr-PMO) with uniform hexagonal arrangement were synthesized by two different synthesis routes using 1,2-bis(triethoxysilyl)ethane (BTEE) and tetraethyl orthosilicate (TEOS) as silica sources and alkyltrimethyl ammonium salts (ATMA) ...

Syntheses of new poly(trifunctional-silyl)alkanes, which are potent coupling agents of hybrid organic–inorganic materials have been thoroughly examined. Optimization of the Benkeser reaction using chloroform, trichlorosilane and tri-n-butylamine (respective ratios 1:4.5:3) afforded bis(trichlor...

Imidazo[1,5-a]pyridines 1 are prepared by reaction of N-vinylic phosphazene 3, obtained from phosphorus ylide 5 and 2-cyanopyridine 4, with aldehydes. Formation of fused heterocycles 1 can be explained through aza-Wittig reaction of phosphazene 3, followed by 1,5-electrocyclic ring closure of th...

We investigated the biological activity of a series of substituted chromeno[3,2-c]pyridines, including compounds previously synthesized by our group and novel compounds whose syntheses are reported here. Tandem transformation of their tetrahydropyridine ring under the action of activated alkynes...

A method for the preparation of 3-fluoroalkyl substituted 2-aza-butadienes 6 by aza-Wittig reaction of 3-fluoroalkyl-N-vinylic phosphazenes 4 and aldehydes 5 is reported. [4+2] Cycloaddition reaction of these heterodienes 6 with enamines 9 gives fluoroalkyl substituted pyridine 15, 16, 24–27 an...

Reaction of N-vinylic phosphazenes with α,β-unsaturated ketones leads to the formation of pyridines derived from β-amino acids in a regioselective fashion. The use of functionalized enones derived from α-acylstyryl-carboxylates or -phosphonates affords biologically active asymmetrical and sy...

4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) is widely applied as a fluorescent tagging reagent in biochemistry, as a derivatization agent in analytical chemistry, and as a component for design of fluorescent nanoparticles. Four new 7-nitrobenzo-2-oxa-1,3-diazole (NBD)-tagged polyamines cont...

A range of tertiary amines having electron-withdrawing groups were activated in situ by benzyne, generated from 2-(trimethylsilyl)phenyl triflate and a fluoride source, and participated in the Darzens-type reaction with carbonyl compounds, imines, and vinyl ketones to afford structurally diverse...

One-pot cyclization of alk-4-ynals with primary aliphatic amines and azoles in DMSO under the action of KOH affords 1-alkyl-2-azolyl-5-arylmethylidenepyrrolidines. Similar processes with lithium monoalkylamides in THF give rise to 3-iminocyclopentenes.

Dimethyl maleate was found to be a very reactive and selective acceptor for the aza-Michael addition in comparison to other commonly used electron-deficient alkenes. It reacts efficiently with a variety of aliphatic amines in complete absence of any catalyst and solvent at room temperature. Unde...

The syntheses and full spectral (NMR, MS, IR), thermal (DSC) and ion chromatographic characterization of two series of amine-derived ionic liquids bearing 4-vinylbenzyl substituent and having chloride or bis(trifluoromethanesulfonyl)amide anion have been presented. The analysis of the dependence...

Iron-organic framework Fe3O(BPDC)3 was synthesized, and subsequently utilized as an productive heterogeneous catalyst for the cyclization reaction of N,N-dialkylanilines with ketoxime carboxylates to produce aryl-substituted pyridines. This iron-organic framework catalyst demonstrated remarkably...

The preparation and photophysics of organometallic Ir(III) complexes with 3-phenylpyridazine (H6Clppdz) and its derivative are reported. IrCl3 · nH2O reacts with H6Clppdz, and 3-chloro-6-(3′-methoxyphenyl)-4-methyl-pyridazine (MCOMppdz) to give the corresponding chloride-bridged dimers, (6Clpp...

In this work, the structure of N′-(2-methoxy-benzylidene)-N-[4-(3-methyl-3-phenyl-cyclobutyl)-thiazol-2-yl]-chloro-acetic hydrazide, (C24H24ClN3O2S), was characterized by X-ray single crystal diffraction technique, IR-NMR spectroscopy and quantum chemical computational methods as both experimen...

Trimethyl(N-morpholino)silane (Me3SiMorph) and dimethyl-di(N-morpholino)silane (Me2SiMorph2) were synthesised. The insertion reactions of both silanes with CO2, n-butylisocyanate (nBuNCO), phenylisocyanate (PhNCO), methylisothiocyanate (MeNCS), n-butylisothiocyanate (nBuNCS) and phenylisothiocya...