Five new supramolecular assemblies based on organic macrocyclic cavitand cucurbit[6] uril (CB[6]) and mono-/polynuclear bismuth(III)-, and mercury(II)-ions were synthesized and structurally characterized by single-crystal X-ray diffraction. They are (H3O)4[Bi2Cl10]·(C36H36N24O12)·14H2O (1), (H...

Incorporation of mannoproteins into the walls of Candida albicans blastospores (yeast phase) was followed by continuous lebelling and pulse-chase experiments. The effect in the process of compounds that interfere with synthesis (papulacandin B) or assembly (calcofluor white) of structural polyme...

Regeneration of Candida albicans protoplasts began with the formation of a chitin network which was complemented after a lag of about 60 min by the deposition of β-glucan. Proteins were incorporated early to the growing structure, beginning with the mannoproteins which are kept in place by non-...

The photocycloaddition of styryl dyes 1, mediated by 1:2 hostguest complexes with cucurbit[8]urils (CB[8]), was studied by fluorescence upconversion techniques. The lifetime of 14.5 ps for photoexcited 1 in aqueous solution and 3.8 ps for that inside the complexes were gained from the fluorescen...

The analysis of the IR vCO bands of the 2-ethylsulfinyl-(4′-substituted)-phenylthioacetates 4′-Y-C6H4SC(O)CH2S(O)Et (Y = NO2 1, Cl 2, Br 3, H 4, Me 5, OMe 6) supported by B3LYP/6-31G(d,p) calculations along with the NBO analysis for 1, 4 and 6 and X-ray analysis for 3, indicated the existence ...

The in silico evaluation for the three previously synthesized compounds (Methyl (MMA), propyl (PMA) and isopropyl (IMA) N-methylanthranilate), MMA and IMA originally found in the leaf essential oil of Choisya ternata, provided a very good confirmation for the in vivo pharmacological results obta...

An efficient catalytic system containing [RuCl2(η6-p-cymene)]2 and one P,N ligand, N-diphenylphosphino-2-aminopyridine (L1) was loaded in catalyzing the alkylation of ketones with primary alcohols for a diverse array of substrates. Other five P,N ligands based on pyridin-2-amine and pyrimidin-2...

Our previous study has revealed 4-(4-(4-chlorophenyl)-1,4-diazepan-1-yl)-1-(4-fluorophenyl)butan-1-one·2HCl (SYA013) 1 as a sigma ligand with moderate selectivity for the sigma-2 receptor. Given the overexpression of sigma receptors in solid tumors and reports of sigma ligands with anticancer a...

Fluorinated 3-acetoxy-2-(methoxyimino)butyrates were resolved by lipase to give the corresponding alcohols and the acetates in high optical purity. The resolved alcohols were readily converted into mono-, di-, and trifluorothreonine and allo-threonine derivatives by hydrogenation of the methoxyi...

The synthesis of two diastereomeric cyclo[Asp-N-Bn-Ser] diketopiperazines (2a and 2b) was investigated. Initial formation of the Boc-aspartyl-N-benzyl serine isopeptide methyl esters (4a and 4b) was observed, which derive from the selective O-acylation of unprotected (S)- or (R)-N-benzylserine. ...

Investigations of enhanced sample utilization in thermal ionization mass spectrometry (TIMS) using porous ion emitter (PIE) techniques for the analyses of trace quantities of americium and plutonium were performed. Repeat ionization efficiency (i.e., the ratio of ions detected to atoms loaded on...

The numerical transmutation of Americium heterogeneous loaded for one cycle in thermal high flux reactor category was realized. The transmutation calculations are performed based on ChainSolver 2.34 code. A comparison with the measurement and calculation results of the burn up of 241Am irradiate...

A fast method for determination of plutonium, neptunium, americium and curium isotopes in granite has been developed for use following a radiological event. Granite samples are fused with sodium hydroxide to achieve complete dissolution, critical if refractory particles are present. Rapid precip...

In contrast to the straight final disposal solution, countries like France have opted to reprocess their nuclear reactors spent fuel and defined another way to take care of sensitive elements such as the plutonium or minor actinides. Even in countries which have chosen to reprocess their spent f...

Minor actinides transmutation is the process of decreasing the long term radiotoxicity of the nuclear spent fuel by submitting it to a neutron flux so as to achieve fission of the heavy nuclides concerned. In the case of a closed fuel cycle, minor actinides are the main contributors to the spent...

In this paper, a simple analytical procedure was developed to measure americium isotope ratios and concentration with high accuracy. The method was tested during the participation in a round robin test organized by the Analytical Methods Committee of the French Atomic Energy Commission. The meas...

Sludge biochar as promising low-cost adsorbent has increasingly gained interests, but its poor surface functionality severely undermines its adsorption capacity and selectivity. Here a facile amino functionalization strategy was first proposed to enhance the surface functionality of sewage sludg...

Artificial maturation of Maoming oil shale kerogen (Type I) was performed at a heating rate of 5 °C/h in a closed Au tube system. Yields of pyrolysis products (C1–5, C6–14, C14+ and insoluble residue) were quantified. The insoluble kerogen residue was analyzed using Rock-Eval, elemental analy...

A series of novel benzo[d]imidazolyl tetrahydropyridine carboxylates 7a–n have been synthesized by one-pot multi-component reaction of (E)-5-(benzylidene amino)-1H-benzo[d]imidazole-2-thiol 3, 5-amino-2-mercapto-benzimidazole 4, aromatic aldehyde 5, and ethyl acetoacetate 6 in acetonitrile usin...

Compound 1 exhibits potent binding inhibition activity against a corticotropin-releasing factor 1 (CRF1) receptor (IC50 = 9.5 nM) and in vitro antagonistic activity (IC50 = 88 nM) but is rapidly metabolized by human hepatic microsomes (182 μL/min/mg). Here we identified metabolically stable com...