Two Neoproterozoic-Cambrian shale suites that consist of normal (NBS) and metal-rich (HMBS) black shales from the Teplá-Barrandian Unit, Bohemian Massif (Czech Republic) are studied in terms of their Cu, Zn, Cr and Re–Os isotopic compositions to improve our knowledge of elemental and isotopic ...

This study provides the dietary intakes of six trace elements (cadmium, chromium, copper, manganese, selenium and zinc), generally characterized by both nutritional and toxicological features depending on their exposure. Being diet the most relevant source of exposure to trace elements in non-pr...

BackgroundThe infant's own mother's milk, fortified with proteins, minerals, and vitamins, is considered the best food for low-birth-weight infants. This paper describes the process to obtain a liquid human milk fortifier.

Considering that the phospholipids and glycerophosphoric acid are the basic materials throughout the metabolism of the whole life period and the bone is composed of organic polymer collagen and inorganic mineral apatite, a novel self-setting composite of magnesium glycerophosphate (MG) and di-ca...

Tissue engineering (TE) is a promising approach for repairing diseased and damaged bone tissue. Injectable hydrogel based strategies offer a wide range of applications in rapid recovery of bone defects by acting as filler materials and depots for delivering various bioactive molecules and averti...

Due to its moldability, biocompatibility, osteoconductivity and resorbability, calcium phosphate cement (CPC) is a highly promising scaffold material for orthopedic applications. However, pH changes and ionic activity during the CPC setting reaction may adversely affect cells seeded directly on ...

ObjectivesThis study aimed to evaluate the effect of low-fluoride toothpastes with calcium glycerophosphate (CaGP) on enamel remineralization in situ.

The design and development of bioactive materials that are inherently conducive for osteointegration and bone regeneration with tunable mechanical properties and degradation remains a challenge. Herein, we report the development of a new class of citrate-based materials with glycerophosphate sal...

A four-step synthesis of (3aR*,6S*,7aR*)-6,7,7-trimethylhexahydro-2-benzofuran-1(3H)-one 2 has been developed. Lactone 2 is an intermediate in a synthesis of γ-irone. Opening of the Diels–Alder adduct 5 with ethanol afforded hemiester 6b with 87:13 regioselectivity. Subsequent chemoselective r...

The principal constituents of iris oil, (−)-cis-α-irone and (−)-cis-γ-irone, and their enantiomers, were synthesized from (−)- and (+)-2,2,4-trimethyl-3-cyclohexene-1-carboxylic acids. The racemic acid was resolved by recrystallization of its salt with a chiral amine, or by enzymatic hydrolysi...

This work contains a complete account of the preparation of all the ten enantiopure isomers of irone, the odoriferous principle of orris root oil, by means of enzyme-mediated approaches, starting from commercial racemic Irone alpha®. To cite this article: E. Brenna et al., C. R. Chimie 6 (2003).

A toxicologic and dermatologic review of α-irone when used as a fragrance ingredient is presented.

Using PMDR techniques, the top two zero-field triplet levels in 9,10-dichlorophenanthrene and 1,2,3,4-tetrachloronaphthalene are shown to be most favoured by S1 → T1 ISC and T1 → S0 phosphorescence. Spin—orbit vibronic coupling via CCl out-of-plane modes and static distortions of the heavy ...

The ratio of 1,3,6,7-T4CN (no. 44) to 1,4,6,7-T4CN (no. 47) in the breast muscles and liver of black cormorant was 0.65 and 0.47, respectively, which is much higher than in environmental matrices such as sediment (0.015), plankton (0.033), mussel (0.023), crab (0.19), fishes (0.080), harbour por...

The resolution of the phosphorescence from 1,4,5,8-tetrachloronaphthalene improves when changing from glassy solution to mixed crystals. However, the energy and lifetime of the emission vary with the crystal host. This sensitivity to the host is rationalized by assuming that crystal packing forc...

The regiochemistry of the photolysis of three tetrachloronaphthalenes is sharply dependent upon the presence of triethylamine. Analysis of the steady state kinetics in the presence and absence of quenchers and triethylamine provides a mechanistic rationale in terms of triplet, triplet excimer, a...

1,3,5,8-tetrachloronaphthalene (1,3,5,8-TeCN) is a Persistent Organic Pollutant (POP) that belongs to the group of polychlorinated naphthalenes (PCNs). The aim of the study was to investigate the maternal-fetal distribution and prenatal toxicity of 1,3,5,8-TeCN after its administration to pregna...

Polychlorinated naphthalenes (PCNs) are thought to interact with the aryl hydrocarbon receptor (AHR) and to have enzyme-inducing properties comparable to polychlorinated dibenzo-p-dioxins, therefore activation of steroid hormone receptors in endocrine tissues is also possible.The aim of the pres...

Bromination of 3-cyclohexene-1-carboxylic acid (1) gives mixtures of the trans-dibromo-derivatives 3 and 4 and cis-3-hydroxy-trans-bromocyclohexane-1-carboxylic acid lactone (5). Lactone 5 is obtained by brominating 1 in the presence of triethylamine, showing that halogen preferentially attacks ...

Free radical hydrostannation of methyl cyclohexene-1-carboxylate (I) and methyl indene-3-carboxylate (III) with trialkyltin hydrides, R3SnH (R  Me, n-Bu, Ph) gives the energetically unfavourable cis products, 2-trialkylstannyl cyclohexanecarboxylate (II) and 2-trialkylstannyl indane-1-carboxyl...