Isobaric vapor–liquid equilibrium(VLE) data for the quaternary system methyl acetate + methanol + isopropanol + isopropyl acetate and the constituent binary system methyl acetate + isopropyl acetate have been determined at 101.3 kPa with a modified Rose still. The rest of binary systems VLE dat...

The liquid-liquid equilibrium (LLE) data for the ternary systems of ethyl acetate + 2,2,3,3-tetrafluoro-1-propanol + water and isopropyl acetate + 2,2,3,3-tetrafluoro-1-propanol + water were measured at T = 298.15 K and T = 318.15 K under 101.3 kPa. Bachman and Hand equations were selected to ch...

Mannich base derivatives 1–3 were biotransformed through tandem enzymatic reactions by using several microorganisms isolated from Brazilian biomes. The hydrochlorides 1 and 3 produced propiophenone 1a, α,β-unsatured ketone 2c and alcohol (S)-1b (yield 40%, e.e. 81%, Aspergillus terreus). The ...

Artificial neural networks (ANNs) were regarded as data-mapping networks with strong nonlinear fitting abilities. A 2-6-2 network was used to determine the competitive adsorption isotherm of 2-phenylethanol (PE) and 3-phenylpropanol (PP). The ANN results were forms of data mapping rather than th...

Resting cells of Fusarium moniliforme strain MS31 produced (R)-1-phenylpropanol from propylbenzene. The components of the medium and the reaction conditions were adjusted to increase the specific activity of the hydroxylating enzyme involved. Glucose and sodium nitrate were selected as carbon an...

ObjectiveTo study the constituents in the whole plant of Boschniakia rossica.

(S)-3-Chloro-1-phenylpropanol is an important chiral precursor for numerous antidepressants such as tomoxetine. A high enantiomeric excess (e.e.) of (S)-3-chloro-1-phenylpropanol can be achieved by asymmetric reduction of 3-chloropropiophenone using Saccharomyces cerevisiae CGMCC 2266 cells immo...

The relationship between the structures of a number of phenylpropanols and related compounds and their enantioselectivity on supercritical fluid chromatography using Chiralcel OD and Chiralcel OB cellulose based columns has been examined. Changes in the resolution with different temperatures, pr...

The retention and the separation of the enantiomers of 1-phenylpropanol (1PP), 2-phenylpropanol (2PP), and 3-chloro-1-phenylpropanol (3CPP) on silica-bonded quinidine carbamate under normal phase HPLC conditions were investigated. A relatively high selectivity of the stationary phase for 3CPP an...

2-methyltetrahydrofuran, an ecofriendly substitute for traditional organic solvents, was employed to construct cosolvent system for synthesis of (S)-3-chloro-1-phenylpropanol by permeabilized recombinant Escherichia coli containing the YOL151W reductase and Escherichia coli containing d-glucose ...

ObjectiveTo study the constituents in the twigs and leaves of Rhododendron primulaeflorum.

A toxicologic and dermatologic review of 2,2-dimethyl-3-phenylpropanol when used as a fragrance ingredient is presented. 2,2-Dimethyl-3-phenylpropanol is a member of the fragrance structural group Aryl Alkyl Alcohols and is a primary alcohol. The AAAs are a structurally diverse class of fragranc...

An efficient catalytic double asymmetric induction during the tandem transetherification–intramolecular hetero Diels–Alder reaction has been developed. The enantioselective tandem reaction of methyl (E)-4-methoxy-2-oxo-3-butenoate with rac-6-methyl-5-hepten-2-ol has been achieved to provide me...

Oxidation of p-anisaldehyde by chromic acid produces p-anisic acid under kinetic condition [p-anisaldehyde]T≫[Cr(VI)]T. This oxidation reaction is performed also in presence of micellar catalysts in aqueous media at room temperature. The progress of the reaction is monitored spectrophotometrical...

Phospholipase A2 catalyses the hydrolysis of the ester bond of 3-sn-phosphoglycerides. Here, we report the crystal structures of the free and anisic acid-bound triple mutant (K53,56,120M) of bovine pancreatic phospholipase A2. In the bound triple mutant structure, the small organic molecule p-an...

A study was made of the oxidation of o-tolualdehyde over fused vanadium oxide from 360° to 460° in a flow system.The reaction course consists of four parallel routes: (1) the stepwise oxidation of o-tolualdehyde to phthalic anhydride via o-toluic acid and phthalide intermediates; (2) the direc...

The gas phase hydrogen treatment of benzaldehyde and o-tolualdehyde was studied over a Ni/SiO2 catalyst prepared by homogeneous precipitation/deposition. The reactions were conducted in the absence of diffusion limitations and reproducible turnover frequencies are presented. The products generat...

The first direct synthesis of substituted anthracenes from o-tolualdehydes and aryl iodides via a Pd(II)-catalyzed CH arylation using an alcohol-bearing transient directing group and subsequent AgOTf-assisted electrophilic aromatic cyclization is described. New transient directing groups consist...

This chapter deals with [4 + 2] anionic annulation of activated ortho toluates and ortho tolualdehydes. The activating groups belong to esters, cyanide, nitro, sulfones, sulfoxides, thioacetals, etc. Based on the activating groups, the annulations have been subclassified as the “Schmid annulati...

A high-performance thin-layer chromatographic method for simultaneous determination of nadifloxacin, mometasone furoate, and miconazole nitrate was developed and validated as per International Conference on Harmonization guidelines. High-performance thin-layer chromatographic separation was perf...