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SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

Sichuan Zhongbang S&T Co.,Ltd. is a complex enterprise specializing in the research, development, manufacturing and trade of fine chemicals, domestic hygiene, pesticide intermediates and pharmaceutical intermediates; the main products includ

3-Methyl butynol

Cas:115-19-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3-Methyl butynol Manufacturer/High quality/Best price/In stock

Cas:115-19-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Methyl-3-Butyn-2-Ol supplier in China

Cas:115-19-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-methylbut-3-yn-2-ol

Cas:115-19-5

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Methyl-3-butyn-2-ol

Cas:115-19-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2-Methyl-3-Butyn-2-ol_

Cas:115-19-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Items Technical index Product name 2-Methyl-3-butyn-2-ol CAS No 115-19-5 Molecular formula

2-Methyl-3-butyn-2-ol

Cas:115-19-5

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Wuhan Kemi-Works Chemical Co., Ltd

2-Methyl-3-butyn-2-ol Molecular Formula:C5H8O Assay: 99%min. (GC) Acetone: 1% max Moisture: 1% max Appearance:Colorless or slightly yellow liquid Storage:Store in dry and cool place with good seal Package:165KG/ galvanized iron drum App

3-Methyl butynol

Cas:115-19-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Methyl-3-Butyn-2-ol

Cas:115-19-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Methyl butynol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Methyl-3-Butyn-2-Ol

Cas:115-19-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colourless liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediat

3-Butyn-2-ol, 2-methyl-

Cas:115-19-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 2-Methyl-Butyn-2-ol CAS No.:115-19-5 Molecule Formula:C5H8O Molecule Weight:84.12 Purity: 98.0% Package: 180kg/drum Description:Colorless clear liquid Manufacture Standards:Enterprise Standard TESTING

High Quality 2-Methyl-Butyn-2-ol

Cas:115-19-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...)

3-Methyl butynol CAS NO.: 115-19-5

Cas:115-19-5

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp

3-Methyl butynol

Cas:115-19-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Methyl-3-butyn-2-ol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-Methyl-3-butyn-2-ol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2-Methyl-3-Butyn-2-Ol

Cas:115-19-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers408.Safe and fa

2-Methyl-3-butyn-2-ol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

3-Methyl butynol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

2-Methyl-3-Butyn-2-Ol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

2-Methyl-3-butyn-2-ol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 115-19-5 with competitive price

Cas:115-19-5

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3-Butyn-2-ol, 2-methyl-

Cas:115-19-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

2-Methyl-3-Butyn-2-Ol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Other

inquiry

Luyunjia Chemistry Xiamen Limited

Xiamen Luyunjia Trading Co.,Ltd Package:1kg/bag; 998kg/drum, or as customer's request. Application:Xiamen Luyunjia Trading Co.,Ltd Transportation:DHL, EMS, FedEx, TNT, AIR, SEA Port:Beijing,Shanghai,Guangzhou ,China main port

3-Methyl butynol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketing of chemicals. We have earned ourselves a good reputation at home an

2-Methyl-3-Butyn-2-ol manufacture

Cas:115-19-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

115-19-5 Application:intermediate

2-Methyl-3-butyn-2-ol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

2-Methyl-3-butyn-2-ol 115-19-5

Cas:115-19-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

3-Methyl butynol

Cas:115-19-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

acetone
67-64-1

acetone

acetylene
74-86-2

acetylene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With sodium In methanol at 0 - 5℃; for 1h; Solvent; Reagent/catalyst; Autoclave; Inert atmosphere; Large scale;99.2%
Stage #1: acetylene With sodium amide In ammonia at -50℃; for 0.5h;
Stage #2: acetone at -50 - 25℃;
87.9%
Stage #1: acetylene With potassium hydroxide monohydrate In dimethyl sulfoxide at 10 - 15℃; for 7h;
Stage #2: acetone In dimethyl sulfoxide at 10 - 15℃; for 9h; Temperature;
82%
polymethyl(3-hydroxy-3-methyl-1-butynyl)siloxane

polymethyl(3-hydroxy-3-methyl-1-butynyl)siloxane

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 25℃; for 12h;99%
acetone
67-64-1

acetone

acetylene
74-86-2

acetylene

A

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

B

2,5-dihydroxy-2,5-dimethyl-3-hexyne
142-30-3

2,5-dihydroxy-2,5-dimethyl-3-hexyne

Conditions
ConditionsYield
With potassium hydride In tetrahydrofuran at 30℃; under 759.826 Torr; for 2.25h;A 7%
B 91%
Stage #1: acetone; acetylene With potassium 2-methylpropan-2-olate In xylene at 28 - 35℃; for 1h;
Stage #2: With water
Stage #3: With phosphoric acid Product distribution / selectivity;
A 2.3%
B 90%
Stage #1: acetone; acetylene With potassium 2-methylpropan-2-olate In xylene at 10 - 20℃; for 1h;
Stage #2: With water
Stage #3: With phosphoric acid Product distribution / selectivity;
A 79%
B 3%
acetone
67-64-1

acetone

lithium acetylide
70277-75-7

lithium acetylide

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
Stage #1: acetone; lithium acetylide; 4,4'-di-tert-butylbiphenyl In tetrahydrofuran at 0℃; for 2h;
Stage #2: With water In tetrahydrofuran at 20℃; Product distribution / selectivity;
81%
Stage #1: acetone; lithium acetylide; naphthalene In tetrahydrofuran at 0℃; for 2h;
Stage #2: With water In tetrahydrofuran at 20℃; Product distribution / selectivity;
56.5%
2-methyl-propan-1-ol
78-83-1

2-methyl-propan-1-ol

acetone
67-64-1

acetone

acetylene
74-86-2

acetylene

A

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

B

2,5-dihydroxy-2,5-dimethyl-3-hexyne
142-30-3

2,5-dihydroxy-2,5-dimethyl-3-hexyne

Conditions
ConditionsYield
Stage #1: 2-methyl-propan-1-ol With potassium hydride In tetrahydrofuran at 30℃; under 759.826 Torr; for 0.25h;
Stage #2: acetone; acetylene In tetrahydrofuran at 30℃; under 759.826 Torr; for 2.25h;
A 74%
B 22%
2-methyl-3-butyn-2-ol 1-ethoxyethyl ether
39807-00-6

2-methyl-3-butyn-2-ol 1-ethoxyethyl ether

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With N,4-dimethyl-N-vinylbenzenesulfonamide; picAuCl2(III) In dichloromethane at 20℃; for 0.25h; Inert atmosphere;60%
acetone
67-64-1

acetone

acetylenemagnesium bromide
4301-14-8

acetylenemagnesium bromide

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
In tetrahydrofuran Heating;47%
Stage #1: acetone; acetylenemagnesium bromide In tetrahydrofuran at 0 - 20℃;
Stage #2: With ammonium chloride In tetrahydrofuran; water
In tetrahydrofuran at -10 - 20℃;
4-Hydroxy-4-methyl-2-pentanone
123-42-2

4-Hydroxy-4-methyl-2-pentanone

sodium acetylide
1066-26-8

sodium acetylide

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

sodium acetylide
1066-26-8

sodium acetylide

acetone
67-64-1

acetone

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

sodium acetylide

sodium acetylide

acetone
67-64-1

acetone

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
at -20℃;
at -20℃;
diethyl ether
60-29-7

diethyl ether

sodium ethanolate
141-52-6

sodium ethanolate

acetone
67-64-1

acetone

acetylene
74-86-2

acetylene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

sodium acetylide
1066-26-8

sodium acetylide

acetone
67-64-1

acetone

acetylene
74-86-2

acetylene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With ammonia
With ammonia
ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

acetylene
74-86-2

acetylene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With diethyl ether nachfolgende Einw. von Aceton;
2,5-dihydroxy-2,5-dimethyl-3-hexyne
142-30-3

2,5-dihydroxy-2,5-dimethyl-3-hexyne

A

acetone
67-64-1

acetone

B

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
Pyrolysis;
With silica gel Pyrolysis;
With calcium carbide Pyrolysis;
3-chloro-3-methylbut-1-yne
1111-97-3

3-chloro-3-methylbut-1-yne

cyclopenta-1,3-diene
542-92-7

cyclopenta-1,3-diene

A

2,2-dimethylbicyclo<3.2.1>oct-6-en-3-one
22940-29-0

2,2-dimethylbicyclo<3.2.1>oct-6-en-3-one

B

3-Chlor-4,4-dimethylbicyclo<3.2.1>octa-2,6-dien
65404-99-1

3-Chlor-4,4-dimethylbicyclo<3.2.1>octa-2,6-dien

C

4-(1,1-Dimethyl-2-propinyl)-2-cyclopenten-1-ol
344257-36-9

4-(1,1-Dimethyl-2-propinyl)-2-cyclopenten-1-ol

D

propargyl alcohol
107-19-7

propargyl alcohol

E

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With potassium hydroxide; silver trifluoroacetate In pentane at 0℃; Mechanism;
C12H13F3O2Se

C12H13F3O2Se

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In benzene at 95℃; for 2h; Yield given;
2-Iodobenzoic acid
88-67-5

2-Iodobenzoic acid

A

2-(3-Hydroxy-3-methyl-but-1-ynyl)-benzoic acid
147454-79-3

2-(3-Hydroxy-3-methyl-but-1-ynyl)-benzoic acid

B

(Z)-3-(2-hydroxy-2-methylpropylidene)-3H-isobenzofuran-1-one
147454-71-5

(Z)-3-(2-hydroxy-2-methylpropylidene)-3H-isobenzofuran-1-one

C

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine 1.) DMF, 1 h, 2.) DMF, a) RT, 1 h, b) 30 deg C, 6 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
diethyl ether
60-29-7

diethyl ether

sodium amide

sodium amide

acetone
67-64-1

acetone

acetylene
74-86-2

acetylene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

acetylene
74-86-2

acetylene

acetonevapour

acetonevapour

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With sodium amide
auf aether.Suspensionen von Natriumamid,Natrium oder Natriumaethylat;
acetone
67-64-1

acetone

calcium carbide

calcium carbide

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With potassium hydroxide; ethanol
acetone
67-64-1

acetone

disodium acetylene

disodium acetylene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
at -20℃;
acetylene
74-86-2

acetylene

potassium acetone

potassium acetone

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With diethyl ether
diethyl ether
60-29-7

diethyl ether

acetylene
74-86-2

acetylene

potassium acetone

potassium acetone

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

acetone
67-64-1

acetone

potassium acetylenide

potassium acetylenide

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With Dimethoxymethane at 0℃;
With dibutyl acetal at -3℃;
With diethyl acetal; poly ether at -10℃;
With xylene; butan-1-ol at -10℃;
With dibutyl acetal at -3℃;
diethyl ether
60-29-7

diethyl ether

acetone
67-64-1

acetone

acetylene
74-86-2

acetylene

potassium

potassium

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

acetylene
74-86-2

acetylene

sodium acetone

sodium acetone

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With diethyl ether
acetic anhydride
108-24-7

acetic anhydride

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

1,1-dimethyl-2-propynyl acetate
1604-29-1

1,1-dimethyl-2-propynyl acetate

Conditions
ConditionsYield
tetrafluoroboric acid; silica gel at 20℃; for 2h;100%
indium(III) chloride at 20℃; for 0.5h;100%
With magnesium(II) perchlorate at 20℃; for 0.5h;100%
phenyl isocyanate
103-71-9

phenyl isocyanate

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

O-α,α-dimethylpropargyl N-phenylcarbamate
6289-19-6

O-α,α-dimethylpropargyl N-phenylcarbamate

Conditions
ConditionsYield
With MoCl2O2(dmf)2 In dichloromethane at 20℃; for 0.333333h;100%
With triethylamine In tetrahydrofuran at 70℃; for 12h; Inert atmosphere;94%
With dmap; triethylamine In tetrahydrofuran at 20℃; for 90h;88%
ethyl vinyl ether
109-92-2

ethyl vinyl ether

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-methyl-3-butyn-2-ol 1-ethoxyethyl ether
39807-00-6

2-methyl-3-butyn-2-ol 1-ethoxyethyl ether

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In dichloromethane at 20℃; for 1h;100%
With sulfuric acid for 0.5h;77%
With hydrogenchloride
triethylsilyl chloride
994-30-9

triethylsilyl chloride

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-methyl-2-<(triethylsilyl)oxy>-3-butyne
17963-41-6

2-methyl-2-<(triethylsilyl)oxy>-3-butyne

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0℃; for 1h;100%
2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

Phenyl azide
622-37-7

Phenyl azide

2-(1-phenyl-1H-1,2,3-triazol-4-yl)-2-propanol
856863-40-6

2-(1-phenyl-1H-1,2,3-triazol-4-yl)-2-propanol

Conditions
ConditionsYield
With triethylamine In neat (no solvent) at 20℃; for 24h; Huisgen Cycloaddition; Inert atmosphere; Green chemistry; regioselective reaction;100%
With Cu(OAc)2-anchored mesoporous SBA-15 catalyst (CuSBA-15-PTAA) In water at 50℃; for 6h;95%
With C39H44ClCuN2(1+) In neat (no solvent) at 25℃; for 1h; Schlenk technique; Inert atmosphere;94%
2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

2,6-dimethylhept-6-en-3-yn-2-ol
28246-76-6

2,6-dimethylhept-6-en-3-yn-2-ol

Conditions
ConditionsYield
With copper(l) iodide; TEA at 60℃;100%
With copper(l) iodide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; potassium iodide; sodium sulfite In water; benzene at 75 - 80℃; for 6h;92%
With potassium carbonate; copper(l) iodide; tetrabutyl-ammonium chloride In N,N-dimethyl-formamide for 16h; Product distribution; Ambient temperature; variation of catalysts and reaction time;88%
2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2,7-dimethyl-octa-3,5-diyne-2,7-diol
5929-72-6

2,7-dimethyl-octa-3,5-diyne-2,7-diol

Conditions
ConditionsYield
With carbon dioxide; sodium acetate; copper dichloride In methanol at 40℃; under 105008 Torr; for 4h;100%
With copper(l) iodide; ethyl bromoacetate; N-ethyl-N,N-diisopropylamine; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran at 20℃;99%
With oxygen; (TBA)4[γ-H2SiW10O36Cu2(μ-1,1-N3)2] In benzonitrile at 99.84℃; under 760.051 Torr; for 2h;99%
allyl bromide
106-95-6

allyl bromide

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

(Z)-2-Bromo-1-hydroxy-1-methyl-2,5-hexadiene

(Z)-2-Bromo-1-hydroxy-1-methyl-2,5-hexadiene

Conditions
ConditionsYield
bis(acetonitrile)palladium(II) bromide 1) 0 deg C, 0.5-1 h, 2) r.t.;100%
bis(benzonitrile)palladium(II) bromide In 1,2-dimethoxyethane at 0 - 20℃; for 6h;
bromobenzene
108-86-1

bromobenzene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-Methyl-4-phenyl-3-butyn-2-ol
1719-19-3

2-Methyl-4-phenyl-3-butyn-2-ol

Conditions
ConditionsYield
With copper(l) iodide; C80H65BrN2O2P4Pd; triethylamine In water for 7h; Reagent/catalyst; Sonogashira Cross-Coupling; Inert atmosphere; Reflux;100%
With copper(l) iodide; diethylamine; triphenylphosphine; palladium diacetate for 36h; Heating;98%
With copper(l) iodide; palladium diacetate; triphenylphosphine; 3-aminopentane for 36h; Inert atmosphere; Reflux;98%
2-Bromo-6-methoxynaphthalene
5111-65-9

2-Bromo-6-methoxynaphthalene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-methyl-4-(6-methoxynaphthalen-2-yl)but-3-yn-2-ol
129112-99-8

2-methyl-4-(6-methoxynaphthalen-2-yl)but-3-yn-2-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine for 17h; Heating;100%
With copper(l) iodide; ethanolamine; triphenylphosphine; palladium on activated charcoal In water; acetonitrile at 80℃; for 15h; Sonogashira cross-coupling;80%
With bis-triphenylphosphine-palladium(II) chloride; copper(I) In triethylamine at 90℃; for 20h;79%
With tetrakis(triphenylphosphine) palladium(0); triphenylphosphine; lithium bromide; copper(ll) bromide In tetrahydrofuran at 90℃; for 2h; Substitution; Title compound not separated from byproducts;
With copper(l) iodide; palladium diacetate; N-ethyl-N,N-diisopropylamine; triphenylphosphine In N,N-dimethyl-formamide at 70℃; for 12h; Inert atmosphere; Glovebox;
1-trifluoromethanesulfonyloxy-4-t-butylcyclohexene
77412-96-5

1-trifluoromethanesulfonyloxy-4-t-butylcyclohexene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-methyl-4-(4-tert-butylcyclohexenyl)but-3-yn-2-ol
96575-62-1

2-methyl-4-(4-tert-butylcyclohexenyl)but-3-yn-2-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; triethylamine In N,N-dimethyl-formamide at 75℃; for 5.5h;100%
(1,1-dimethylethyl)(3-iodophenoxy)dimethylsilane
133910-12-0

(1,1-dimethylethyl)(3-iodophenoxy)dimethylsilane

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

4-[3-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-2-methyl-but-3-yn-2-ol
188957-22-4

4-[3-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine at 75℃; for 16h;100%
2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

para-nitrophenyl bromide
586-78-7

para-nitrophenyl bromide

2-methyl-4-(4-nitrophenyl)but-3-yn-2-ol
33432-53-0

2-methyl-4-(4-nitrophenyl)but-3-yn-2-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In tetrahydrofuran for 12h; Sonogashira Cross-Coupling; Inert atmosphere; Reflux;100%
With copper(l) iodide; triethylamine; triphenylphosphine at 90℃; for 3h; Sonogashira coupling; Inert atmosphere;97%
With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran for 12h; Heating;96%
iodobenzene
591-50-4

iodobenzene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-Methyl-4-phenyl-3-butyn-2-ol
1719-19-3

2-Methyl-4-phenyl-3-butyn-2-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 4h; Sonogashira Cross-Coupling; Inert atmosphere;100%
With copper(l) iodide; triethylamine; triphenylphosphine at 90℃; for 3h; Sonogashira coupling; Inert atmosphere;94%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N,N,N',N'-tetramethylguanidine at 30℃; for 1h; Sonogashira Cross-Coupling; Schlenk technique; Inert atmosphere; Green chemistry;94%
methyl 4-iodobenzoate
619-44-3

methyl 4-iodobenzoate

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

methyl 4-(3-hydroxy-3-methylbut-1-ynyl)benzoate
33577-98-9

methyl 4-(3-hydroxy-3-methylbut-1-ynyl)benzoate

Conditions
ConditionsYield
With copper(l) iodide; (Ph3)2PdCl2; triphenylphosphine; triethylamine for 68h; Sonogashira reaction; Heating;100%
With copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine at 20℃; Inert atmosphere;96.07%
With copper(l) iodide; triethylamine; polymer-bound Pt(0)-phoshine In water; acetonitrile at 55℃; for 8h;95%
4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

4-(3-hydroxy-3-methylbut-1-ynyl)benzaldehyde
117569-57-0

4-(3-hydroxy-3-methylbut-1-ynyl)benzaldehyde

Conditions
ConditionsYield
With triethylamine; triphenylphosphine; palladium diacetate Substitution;100%
Stage #1: 4-bromo-benzaldehyde; 2-methyl-but-3-yn-2-ol With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) In toluene Inert atmosphere;
Stage #2: With diisopropylamine In toluene at 20℃; for 24h; Inert atmosphere;
97%
With copper(l) iodide; triethylamine; triphenylphosphine; palladium diacetate In benzene at 75 - 80℃; for 0.666667h;93%
1-heptyl vinyl ether
764-95-4

1-heptyl vinyl ether

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

1-[1-(1,1-Dimethyl-prop-2-ynyloxy)-ethoxy]-heptane

1-[1-(1,1-Dimethyl-prop-2-ynyloxy)-ethoxy]-heptane

Conditions
ConditionsYield
With trifluoroacetic acid at 20 - 75℃; Addition;100%
diethylene glycol divinyl ether
764-99-8

diethylene glycol divinyl ether

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

3-[1-(2-{2-[1-(1,1-dimethyl-prop-2-ynyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-3-methyl-but-1-yne

3-[1-(2-{2-[1-(1,1-dimethyl-prop-2-ynyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-3-methyl-but-1-yne

Conditions
ConditionsYield
With trifluoroacetic acid at 20 - 48℃; Addition;100%
2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

bis adduct of diethylene glycol divinyl ether and diethylene glycol
273406-64-7

bis adduct of diethylene glycol divinyl ether and diethylene glycol

3-[1-(2-{2-[1-(2-{2-[1-(2-{2-[1-(1,1-dimethyl-prop-2-ynyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-3-methyl-but-1-yne

3-[1-(2-{2-[1-(2-{2-[1-(2-{2-[1-(1,1-dimethyl-prop-2-ynyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-3-methyl-but-1-yne

Conditions
ConditionsYield
With trifluoroacetic acid at 30 - 35℃; for 12h; Addition;100%
2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

8-bromo-3,3-diphenyl-<3H>-naphtho<2,1-b>pyran
227471-78-5

8-bromo-3,3-diphenyl-<3H>-naphtho<2,1-b>pyran

8-(3-hydroxy-3-methylbut-1-ynyl)-3,3-diphenyl-3H-naphtho[2,1-b]pyran
327163-55-3

8-(3-hydroxy-3-methylbut-1-ynyl)-3,3-diphenyl-3H-naphtho[2,1-b]pyran

Conditions
ConditionsYield
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In diethylamine at 20℃; for 14h;100%
With copper(l) iodide; diethylamine; bis-triphenylphosphine-palladium(II) chloride at 20℃; for 16h; Sonogashira coupling;96%
dimethyl (4-nitrobenzylidene)malonate
38323-22-7

dimethyl (4-nitrobenzylidene)malonate

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

5,5-dimethyl-4-methylene-2-(4-nitro-phenyl)-dihydro-furan-3,3-dicarboxylic acid dimethyl ester

5,5-dimethyl-4-methylene-2-(4-nitro-phenyl)-dihydro-furan-3,3-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With copper(l) iodide; n-butyllithium In tetrahydrofuran; hexane at 20℃; for 3h;100%
4-Iodoacetophenone
13329-40-3

4-Iodoacetophenone

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

1-(4-acetylphenyl)-3-methyl-1-butyn-3-ol
95785-28-7

1-(4-acetylphenyl)-3-methyl-1-butyn-3-ol

Conditions
ConditionsYield
With copper(l) iodide; 1-isobutyl-2,2,6,6-tetramethyl-phosphorinane*HBF4; diisopropylamine; bis(benzonitrile)palladium(II) dichloride In 1,4-dioxane at 20℃; for 6h; Sonogashira reaction;100%
With piperidine; copper(l) iodide; polystyrene-N(CH2PPh2)2PdCl2 In 1,4-dioxane at 60℃; for 2h; Sonogashira coupling reaction;94%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Inert atmosphere;90%
3-cyanobromobenzene
6952-59-6

3-cyanobromobenzene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

3-(3-hydroxy-3-methylbut-1-ynyl)benzonitrile
766539-54-2

3-(3-hydroxy-3-methylbut-1-ynyl)benzonitrile

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide at 60℃;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 110℃; for 3h;90%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 60℃; for 3h; Sonogashira Cross-Coupling;
2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

4-n-butoxy-2,6-dibromopyridine
173314-96-0

4-n-butoxy-2,6-dibromopyridine

4-butoxy-2,6-bis(3-hydroxy-3-methyl-1-butynyl)pyridine
675617-47-7

4-butoxy-2,6-bis(3-hydroxy-3-methyl-1-butynyl)pyridine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine at 20℃; for 3.5h; Sonogashira coupling;100%
benzyl bromide
100-39-0

benzyl bromide

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-(1-benzyl-1H-1,2,3-triazol-4-yl)-2-propanol
116557-80-3

2-(1-benzyl-1H-1,2,3-triazol-4-yl)-2-propanol

Conditions
ConditionsYield
With sodium azide In water at 55℃; for 2h; Green chemistry; regioselective reaction;100%
With sodium azide; bis(2-{phenyliminomethyl}pyrrolato)copper(II) In water at 60℃; for 12h; Schlenk technique; regioselective reaction;96%
With sodium azide; sodium L-ascorbate In water at 60℃; for 5h;95%
2-Chloroquinoline
612-62-4

2-Chloroquinoline

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

2-methyl-4-(2′-quinolyl)but-3-yn-2-ol
831235-64-4

2-methyl-4-(2′-quinolyl)but-3-yn-2-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 80℃; for 3h; Sonogashira Cross-Coupling; Inert atmosphere;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 80℃; Inert atmosphere;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine at 40℃; for 0.5h; Sonogashira Cross-Coupling;98%
isobutyraldehyde
78-84-2

isobutyraldehyde

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

(R/S)-2,6-dimethylhept-3-yne-2,5-diol
5486-58-8

(R/S)-2,6-dimethylhept-3-yne-2,5-diol

Conditions
ConditionsYield
Stage #1: 2-methyl-but-3-yn-2-ol With n-butyllithium In tetrahydrofuran; hexane at -40℃; for 0.333333h; Inert atmosphere;
Stage #2: isobutyraldehyde With cerium(III) chloride In tetrahydrofuran; hexane Reagent/catalyst;
100%
Stage #1: 2-methyl-but-3-yn-2-ol With n-butyllithium In tetrahydrofuran at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: isobutyraldehyde With cerium(III) chloride In tetrahydrofuran at 0℃; Inert atmosphere;
92%
Stage #1: 2-methyl-but-3-yn-2-ol With n-butyllithium In tetrahydrofuran at -78℃; for 2h;
Stage #2: isobutyraldehyde In tetrahydrofuran at -65 - 20℃; Further stages.;
81%
Stage #1: 2-methyl-but-3-yn-2-ol With n-butyllithium at -78℃; for 1h; Inert atmosphere;
Stage #2: isobutyraldehyde at -78 - 20℃; Inert atmosphere;
2,6-diiodo-4-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-pyridine
917505-64-7

2,6-diiodo-4-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-pyridine

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

4-(6-(3-hydroxy-3-methyl-but-1-ynyl)-4-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-pyridin-2-yl)-2-methyl-but-3-yn-2-ol
1029916-41-3

4-(6-(3-hydroxy-3-methyl-but-1-ynyl)-4-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-pyridin-2-yl)-2-methyl-but-3-yn-2-ol

Conditions
ConditionsYield
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In diethylamine at 20℃; for 5h; Sonogashira reaction;100%
4-[ethoxydi(prop-2-enyl)silyl]iodobenzene
959419-50-2

4-[ethoxydi(prop-2-enyl)silyl]iodobenzene

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

1-[diallyl(ethoxy)silyl]-4-(3-hydroxy-3-methyl-1-butynyl)benzene

1-[diallyl(ethoxy)silyl]-4-(3-hydroxy-3-methyl-1-butynyl)benzene

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; triphenylphosphine; Pd2(PPh3)2Cl2 In tetrahydrofuran at 50℃; for 1.5h; Sonogashira coupling;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine In tetrahydrofuran at 50℃; Sonogashira coupling;
bis(triphenylphosphine)palladium(II) dichloride

bis(triphenylphosphine)palladium(II) dichloride

4-iodobenzo[b]thiophene-2-carbonitrile
154629-36-4

4-iodobenzo[b]thiophene-2-carbonitrile

2-methyl-but-3-yn-2-ol
115-19-5

2-methyl-but-3-yn-2-ol

4-(3-hydroxy-3-methylbut-1-ynyl)benzo[b]thiophene-2-carbonitrile
154629-77-3

4-(3-hydroxy-3-methylbut-1-ynyl)benzo[b]thiophene-2-carbonitrile

Conditions
ConditionsYield
With CuI In triethylamine100%
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