Chronic manganese exposure causes selective toxicity to the dopaminergic system, resulting in a parkisonian-like neurological condition known as manganism. Manganese causes a typical apoptosis, which includes activation of the caspase cascade and DNA fragmentation in PC12 cells. Caspase-3 is a m...

Given their involvement in catalysis, infection, and biofilm formation, Fe and Mn are essential for bacterial survival and virulence. In this study, we found that Streptococcus pneumoniae (S. pneumoniae) could grow in the Mn-deficient medium (MDCM). Furthermore, findings showed that the Fe conce...

The main object of this paper is to carry out experimental study to find the biodegradation of an insoluble phospholipid, lecithin by bacterial strains into water soluble phosphate compounds and other valuable products that are beneficial for biotic and abiotic systems of the soil. Lecithin is p...

This article reviews the effects of lead on genetic systems in the context of lead's various other toxic effects and its abundance and distribution in the environment. Lead is perhaps the longest used and best recognized toxic environmental chemical, yet it continued be used recklessly unti...

Previous studies have suggested that exposure to heavy metals may be a risk factor in coronary atherosclerotic heart disease in humans as well as in experimental animals. Little is known however on the mechanism underlying the effect of heavy metals on the development of atherosclerosis. In this...

Millions of humans are exposed occupationally and environmentally to lead, mercury and cadmium compounds. Mercury compounds are less abundant but some of them belong to the most toxic chemicals which are known. We evaluated the literature to find out if these metals act in humans as genotoxic ca...

Inorganic lead is the most extensively studied toxic agent. In addition to occupational exposure, there is widespread exposure in the general environment, although this has decreased dramatically after the ban of lead addition to gasoline. Toxic effects may occur in both the central and peripher...

To evaluate Chinese children's blood lead levels (BLLs) and identify its distribution features, we collected articles on children's BLLs published from Jan, 2004 to Aug, 2007 with sampling time since 2001, by searching Chinese Biomedical Disk (CBMDisk), Chinese Journal Full-test Databa...

The solid phase of lead(II) acetate trihydrate and a solution of this compound in methanol as a potential monodentate ligand and in 2-methoxyethanol as a potential bidendate ligand were investigated by IR- and EXAFS-spectroscopy. The structures of the lead compound in methanol and 2-methoxyethan...

A composite consisting of lead ruthenate nanocrystals with an expanded pyrochlore structure on reduced graphene oxide nano-sheets, is reported as an efficient bifunctional catalyst for both oxygen reduction reaction (ORR) and oxygen evolution reaction (OER). Comparative studies for ORR show that...

Lead CASRN (7439-92-1) is a soft, malleable post-transition metal. It was one of the first metals used by humans (since 6400 BCE), as found in modern-day Turkey. It has a wide variety of uses, such as batteries, paints, sheet metal, bearings, solder, piping, and ammunition. However, its well-est...

Mercury is known to be associated with both acute and chronic poisoning. A 36-year-old man intentionally ingested mercuric chloride (HgCl2) and died within 24 h. Post-mortem CT images showed oral, esophageal and gastric wall hyperdense “staining”. On toxicological analysis, the blood concentra...

A 57-year-old pharmacist was found dead 11 days after his disappearance. At the autopsy, samples of blood, urine, gastric content were obtained. Presence of ethanol, cyanide and mercury were detected in some samples. Cyanide and mercury were identified and quantified using high-performance liqui...

Effects of aluminum on water distribution system and human health mainly attribute to its speciation in drinking water. Laboratory experiments were performed to investigate factors that may influence aluminum speciation in water supply system. The concentration of soluble aluminum and its transf...

Silic acid is always present in natural waters and interactions between silicic acid and aluminium have been reported over wide concentration ranges. Since aluminium salts are commonly used as coagulants in water treatment, it is possible that their effects may be modified by the presence of sil...

Zeta potentials and sizes of aluminum salt precipitates were examined as a function of solution pH at different concentrations, based on laser Doppler velocimetry and dynamic light scattering techniques. A great difference was observed in zeta potential and size of the aluminum hydroxide precipi...

AimsClinical use of doxorubicin, an effective chemotherapeutic agent, has limited uses due to dose-dependent cardiac toxicity. It has been supposed that the production of free radicals and calcium ions overload can lead to cardiac toxicity. Magnesium is a cardioprotective drug which inhibits lip...

Magnesium (Mg) is a crucial divalent cation with more than 300 cellular functions. This ion shows therapeutic properties in several neurological diseases. Although there are numerous basic evidences showing that Mg can inhibit pathological processes involved in neuroglial degeneration, this low-...

BackgroundThe purpose of the present study was to evaluate the protective effect of Magnesium Isoglycyrrhizinate (MI) on Epirubicin (EPI)-induced hepatic encephalopathy (HE) and explore its underlying mechanism.

The impact of vanadium (V) and magnesium (Mg) applied as sodium metavanadate (SMV, 0.125 mg V/ml) and magnesium sulfate (MS, 0.06 mg Mg/ml) on oxidative stress markers in bone of male Wistar rats was investigated. Some of them were also measured in the liver, e.g. l-ascorbic acid (hepatic L-AA)....