The hydrogenation of low temperature coal tar was carried out over a MoNiWP/Al2O3 catalyst under mild conditions to produce clean liquid fuel. The effects of temperature, pressure and liquid hourly space velocity (LHSV) on product composition were determined by FT-IR and GC–MS analysis. The fee...

Co-pyrolysis of biomass with abundantly available materials could be an economical method for production of bio-fuels. Pyrolysis behavior of rice straw (RS) and water hyacinth (WH) were carried out in fixed bed reactor at temperature ranging from 300 to 450 °C at a heating rate of 20 °C/min. C...

The hypothesis was tested that serotonin (5-HT) modulates 3,4-methylenedioxymethamphetamine (MDMA)-induced increase in dopamine synthesis. Rats were treated with the selective 5-HT2 receptor agonist (R)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (R-DOI), the selective serotonin releasing agen...

The effects of two selective 5-HT-releasing agents, 4-methylthioamphetamine (MTA) and 5-methoxy-6-methyl-2-aminoindan (MMAI), on the extracellular 5-HT concentration in the dorsal hippocampus was determined by microdialysis in anesthetized rats. After i.p. administration of 1 or 5 mg/kg of eithe...

The behavioral effects of 5-methoxy-6-methyl-2-aminoindan (MMAI) were examined using the drug discrimination procedure and direct observation for classification of the characteristic syndrome induced by MMAI. The stimulus effects of MMAI were studied in 5 different groups of rats trained to disc...

A convenient and short synthesis (3 steps, 50% overall yield) of the bifunctional chelating agent 1-(4-aminobenzyl)-1,4,8,11-tetraazacyclotetradecane-N′-,N″-,N‴-triacetic acid (4) via a boron-protection strategy is reported.

The synthesis of a series of N-alkylated 4-(4′aminobenzyl)-2-oxazolidinones is described using a synthetically useful scheme which avoids the use of phosgene—since the derivatization is undertaken with the oxazolidin-2-one ring intact. The compounds were tested for human placental aromatase (A...

Nowadays metal-organic frameworks (MOFs) have aroused great interest because of their fascinating tunable structures and unusual functional properties. In the recent years, MOFs have been used as new sensing materials to effectively detect cations, anions and nitroaromatic complexes due to their...

In this work a flexible multi-dentate 1-(4-aminobenzyl)-1,2,4-triazole (abtz) ligand has been employed, two novel triazole-Cu(II) coordination polymers {[Cu(abtz)2(Br)2]·(H2O)2}n (1) and {[Cu(abtz)2]·(SiF6)·(H2O)2}n (2) have been isolated under solvo-thermal conditions. 1 is a 2D neutral CuII...

A fluorescent probe (Z)-3-((4-(4-aminobenzyl) phenyl) amino)-1,3-diphenylprop-2-en-1-one (L) was synthesized and characterized by IR, 1H NMR, ESI mass, UV–visible and fluorescence spectroscopy and by single crystal X-ray diffraction. The molecule has a stable helical structure due to intermolec...

Chitosan, as a biocompatible polymer, is very attractive for biomedical applications. Continues studies are performing for improving its physicochemical features in order to make it more suitable for such approaches. In this study, methylated 4-N,N dimethyl aminobenzyl N,O carboxymethyl chitosan...

Treatment of 4-aminobenzyl esters with Al2O3 in DCM at rt afforded the dealkylative dimerized 4,4′-diamino-diphenylmethanes in satisfactory yield. The reaction may proceed via a quinone methide iminium ion intermediate, which may then undergo Michael type addition followed by retro-aldol extrus...

A novel aromatic diamine monomer containing preformed aromatic–aliphatic amide and ether linkage, bis-[(4-aminobenzyl)-4-benzamide] ether (BABE) was prepared from 2-phenylacetonitrile. BABE was characterized by FT-IR, 1H NMR, 13C NMR and mass spectrometry. Five new aromatic polyamides were prep...

SummaryThe thalassaemias are the most common genetic disorders of man, and over the last decade the molecular epidemiology of these defects has been studied in detail. After briefly reviewing the great diversity of mutations giving rise to these conditions, four global regions are discussed in m...

Herein, a newly designed and synthesized fiber-supported [email protected](I) served as efficient and recyclable polymer-supported copper complex catalysts for alkyne coupling and cycloaddition reactions, is reported. The fiber-supported copper complex catalyst was prepared systematically from c...

New 2-aza-1,3-dienes bearing 1 and 3-donor substituents are prepared from N-thioacylacetamidines through deprotonation of N-ylidene acetamidinium iodides. The 2-aza-3-(dimethylamino)-1-(methylthio)-1-phenylbutadiene (3) is trapped in situ by the residual precursor salt acting as a heterodienophi...

The mechanism of action of a novel anti-HIV antibiotic, pradimicin A, has been studied using cell-free (MT-4 cells) and cell to cell (MOLT-4 and MOLT-4/HIVHTLV-3B Cells) HIV infection systems. The data indicate that (1) preincubation of the cells with HIV at 0° for 1 hr, followed by the additio...

This study focused on further analysis of the aggregation behavior of pradimicin derivatives and their interaction with cations in aqueous solution. BMY was compared with two other pradimicin antibiotics (T2 and FB) with the same aglycone moiety but consisting of different substitute groups. The...

The pradimicins are a new class of antifungal agents with activity against the majority of human fungal pathogens. In this study, the in vitro activity of pradimicin BMS-181184 was investigated against a range of the most common species of Aspergillus. The results were compared with itraconazole...

Publisher SummaryIn 1990, Anke, Steglich, and coworkers reported the isolation and structure elucidation of three compounds from the fungus, Xerula melanotricha—xerulin, dihydroxerulin, and xerulinic acid. These are structurally closely related substances; Xerulin and dihydroxerulin were charac...