l-[3-13C]Phenylalanine and l-[3-13C]tyrosine were synthesized. [α-13C]Benzyl bromides were prepared from [13C]carbon monoxide via the palladium-catalyzed carboalkoxylation of aryl halides. The asymmetric carbon corresponding to the 2-position in phenylalanine was introduced by the diastereosele...

Phenyl ring motion in β-form poly(l-phenylalanine) was studied using solid-state deuterium NMR spectroscopy as a function of temperature and echo delay time. The spectra show strong temperature dependence from 173 to 417 K. The line shape is a superposition of two contributions from phenyl grou...

The in vivo rate of conversion of phenylalanine to tyrosine (PheOH) can be estimated using combinations of stable isotope-labeled phenylalanine and tyrosine. We have compared in four healthy adult men the rates of phenylalanine conversion to tyrosine based on the following pairs of primed, conti...

Rubrivivax benzoatilyticus JA2 is a metabolically versatile bacterium, thrives on a wide array of organic compounds under different growth modes. Though genomic insights revealed the aromatic compound catabolic potential of strain JA2 under anaerobic/aerobic conditions, the studies are largely r...

In this work, it was theoretically speculated that enhancing NO adsorption will simultaneously improve SCR performance and Hg0 oxidation on a V-based SCR catalyst. As a result, CeO2 was selected as the modification component. The results indicated that CeO2 modification not only significantly im...

This study investigated the homogeneous formation and reduction of NO from the oxidation of CH4/NH3 to understand the effect of the high concentrations of H2O on NO emissions. The experimental results about the effects of excess oxygen ratio, gas compositions including H2O, CO2, NH3 and recycled...

To achieve high-performance nitric oxide (NO) gas sensing, expanded graphite (EG) was modified with SnO2 and fluorine functional groups. SnO2 was introduced into EG with an aqueous solution of SnCl2, whereas the fluorine functional groups were introduced via fluorine gas. The properties of the s...

Three new ergosterols, ganocalidophins A–C (1‒3), along with four known ones, were isolated from the fruiting bodies of Ganoderma sinense. Their structures were established on the basis of extensive NMR and MS technologies, as well as the single crystal X-ray diffraction. Compounds 1‒3 and 6 ex...

In present study, the NO oxidation on Ni-carbon nanocage and Ni-boron nitride nanocage surfaces was investigated. The Ni–C60 and Ni–B30N30 catalysts can oxidize the NO molecule by Langmuir-Hinshelwood (LH) and Eley-Rideal (ER) mechanisms. In this study, the NO molecule was joined to Ni atom of...

Los linfomas malignos se dividen en dos grupos: los linfomas de Hodgkin (10% de los linfomas) y los linfomas no Hodgkin (LNH). Los LNH consisten en una proliferación tumoral de células procedentes de las estirpes linfoides B o T. Pueden aparecer a cualquier edad de la vida, pero son más frecu...

BackgroundIn 2016, Australia introduced the “No Jab, No Pay” legislation, which removed the option of non-medical exemptions from the vaccination requirements to receive certain family and child care tax benefits. We aimed to gauge parental support for “No Jab, No Pay” and explore how it has...

Herein, we describe an expedient synthesis of the hexaoxygenated guaianolide thapsigargin (1), a potent inhibitor of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA), from the natural product nortrilobolide (2). This protocol involves three key steps: the one-pot substitution-oxidation reacti...

We investigated the protective effects of lentinan against damages to chronic and low-dose radiation (CL-radiation) by using mouse models. The mice were randomized divided into four groups: normal control mice (Ctr), mice exposed to radiation (Rad), irradiated mice treated with low-dose lentinan...

Lentinan (LNT) is a highly functional biomacromolecule, and its sulfated derivatives (sLNT) exhibit improved pharmacological properties compared to LNT. In the present study, LNT extracted from the fermentation broth of Lentinus edodes was sulfated using two methods, conventional heating and nov...

It has been shown that chemotherapy has limited antitumor activity against advanced urothelial bladder cancer (UBC). Consequently, there is an urgent need to develop effective therapeutic methods for patients with advanced UBC. In the present study, the inhibitory effects of lentinan alone, gemc...

The purpose of this research is to study the effect of sulfated lentinan (sLNT) on immune effect of Newcastle disease (ND) vaccine. In immune response test, 14-day-old chickens were vaccinated with ND vaccine then grouped respectively to inject three sLNTs at two doses, once a day for three succ...

In order to investigate the possibility of sulfating modification in improving the anti-viral activity of lentinan (LNT), three kinds of sulfated LNTs (sLNT), sLNT1, sLNT2 and sLNT3 with the degree of substitution of 0.69, 0.98 and 1.37 were prepared by chlorosulfonic acid–pyridine method with ...

Five fractions of lentinan, a β-(1→3)-d-glucan bearing β-(1→6)-d-glucopyranosyl branches, were treated with chlorosulfonic acid for 90 min at 60 °C in pyridine medium to synthesize water-soluble sulfated derivatives having the substitution degree of 1.44–1.76. The 13C NMR spectra of the su...

Sulphated lentinan (sLTN) is known to act as a resistance inducer by causing programmed cell death (PCD) in tobacco suspension cells. However, the underlying mechanism of this effect is largely unknown. Using tobacco BY-2 cell model, morphological and biochemical studies revealed that mitochondr...

The antiviral activities of sulfated lentinan (sLNT) and lentinan (LNT) against tobacco mosaic virus (TMV) in tobacco seedlings and the underlying mechanism were investigated. Compared with LNT, sLNT showed significantly higher inhibitory effects on viral infection and TMV multiplication in a do...