The reaction of ZnCl2 with the non-steroidal anti-inflammatory drug niflumic acid (Hnif) resulted in the formation of complex [Zn(nif-O)2(MeOH)4], 1. When this reaction was performed in the presence of a N,N′-donor heterocyclic ligand such as 2,2′-bipyridine (bipy), 2,2′-bipyridylamine (bipya...

A new strategy for the simultaneous carrying of zinc and yerba mate antioxidants into starch-alginate matrices was developed. Firstly, the use of native corn starch as vehicle of zinc was evaluated and then the starch-zinc carriers were incorporated into calcium alginate beads containing antioxi...

The reaction of ZnCl2 with the non-steroidal anti-inflammatory drug flufenamic acid (Hfluf) led to the formation of complex [Zn(fluf-O)2(MeOH)4], 1. When the reaction takes places in the presence of a N,N′-donor heterocyclic ligand such as 2.2′-bipyridylamine (bipyam), 2.2′-bipyridine (bipy),...

This work is focused on the esterification of fatty acids (commercial oleic mix) with zinc carboxylates (layered metal soap). About 25 experiments were performed, with and without catalyst, yielding a kinetic model based on the Eley–Rideal approach, able to predict fatty acid conversions under ...

Linoleates are required for normal mammalian health and development, but they are also prone to oxidation, resulting in biologically active metabolites such as hydroxyoctadecadienoic acids (HODEs). To investigate the biological activity of 9-EZ-HODE, 10-EZ-HODE, 12-ZE-HODE, and 13-ZE-HODE, the m...

We designed and synthesized a novel linoleate hydroxamic acid (LHA) which demonstrated high selectivity and strong collecting capacity for the beneficiation of manganese ore by selective flotation. The performance of this LHA and oleic acid (OA) used for anionic froth flotation was compared, and...

The antifungal activity of oxine and copper oxinate was investigated using standardized methods to compare efficacy, discriminate activity patterns, elucidate mechanisms of action and establish attributes of relevance to field use. Both agents were shown to be active against a broad range of phy...

Oxine and copper oxinate have a long history of use as fungicides. Ability to chelate and lipophilicity have been regarded as essential to the action of oxine. The most widely held hypothesis on the mechanism of action of oxine holds that oxine is only active when it can form saturated chelates ...

Publisher SummaryThis chapter provides the basic synthesis paths routes for the manufacture of oxine–copper, with a listing of the main raw materials and intermediates used in the synthesis of oxine–copper. Oxine–copper is commercially known as Quinolate and it belongs to the quinoline as wel...

Oxine-copper (OxCu) is generally used as an agricultural pesticide and induces harmful effects on ecosystems. In this study, zebrafish was used to assess the aquatic toxicity of OxCu. To detect the effects on development, embryos of 6 h post-fertilization (hpf) were exposed to 10 μg/L, 20 μg/L...

Relaxin is a peptide hormone, and is secreted during pregnancy in mammalian species. The relaxin family peptides consist of seven peptides: relaxin-1, relaxin-2 (relaxin identified only in human and apes), relaxin-3, and four insulin-like peptides (INSLs) – INSL3, INSL4, INSL5, and INSL6. All p...

The present work demonstrates the experimental and theoretical study of equilibrium CO2 solubility in a potential absorbent, aqueous 1-(2-aminoethyl) piperazine (AEP) and its blend with 2-amino-2-methyl-2-propanol (AMP). The measurements have been conducted at 303.2 to 323.2 K and within the CO2...

In this study, we successfully determined spatiotemporal distribution of curcumin in mice via simple and fast fluorescence detection of native curcumin and stabilized curcumin. We used 2-aminoethyl diphenyl borate (DPBA) as a stabilizer of curcumin, which binds to curcumin and enhances its aqueo...

Total chemical synthesis of the linear tetrasaccharide repeating unit β-D-Glc-(1 → 2)-α-L-Rha-(1 → 3)-α-L-Rha-(1 → 2)-α-L-Rha-CH2CH2NH2 of the O-antigen from Azospirillum brasilense Jm125A2 is accomplished through rational protecting group manipulations of commercially available monosacch...

BackgroundCerebral vasospasm remains a serious problem affecting morbidity and mortality in patients with subarachnoid hemorrhage (SAH) during neurosurgery. We aimed to demonstrate the role of the transient receptor potential channel and other channels for Ca2+ in the etiology of cerebral vasosp...

Quantum chemical techniques such as density functional theory (DFT) have become a powerful tool in the investigation of the molecular structure and vibrational spectrum and are finding increasing use in application related to biological systems. The Fourier transform infrared (FT-IR) and Fourier...

4-(3-Phenylpropyl)pyridine N-Oxide (P3NO) has provided a more active and stable catalytic media for manganese-salen complex 1 in the asymmetric epoxidation of indene.

Several N-(3-phenylpropyl)-substituted spermidine and spermine derivatives were prepared and found to be potent competitive inhibitors of Trypanosoma cruzi trypanothione reductase (seven compounds with Ki values

The control of polymorphs and crystal habit in the cooling crystallization from an acetonitrile/water mixed solvent for the purification of N2-(1(S)-ethoxycarbonyl-3-phenylpropyl)-N6-trifluoroacetyl-L-lysine was investigated. The obtained crystals had three polymorphs (I form, II form and III fo...

Ten N-(3-phenylpropyl)-N′-benzylpiperazines having different substituents on the benzyl moiety were synthesized and evaluated for σ1 and σ2 receptor binding. The σ1 affinities were 0.37–2.80 nM, σ2 affinities were 1.03–34.3 nM, and selectivities, as σ2/σ1 affinity ratios, ranged from 1....