N,N′-bis(salicylidene)-1,2-phenylenediamine, also known as Salophen, is a Schiff base which crystallizes in monoclinic structure and space group P21/c, with four molecules per unit cell. It has been intensely studied in last decades because of its excellent properties with many potential applic...

Indium(III) complex of N, N´-bis(salicylidene)ethylenediamine prepared was characterized, and employed as chemo-sensor for the recognition of HSO4− after studying the following ions (F−, Cl−, Br−, I−, CH3COO−, PO43-, SCN−, PF6−, HSO4−). The results show that the complex selectively detects HSO4...

Metal complexes of substituted N,N′-bis(salicylidene)ethylenediamine ligands are interesting metallo drugs for chemotherapy. Our lead [N,N′-bis(salicylidene)-1,2-phenylenediamine]chloridoiron(III) [Fe(III)salopheneCl] showed excellent in vitro activity against tumor cells sensitive but also re...

Schiff base N,N′-bis(salicylidene)-1,2-phenylenediamine, salophen, is a substance that presents synergism when combined with amikacin against Staphylococcus aureus and Escherichia coli. Measurements of temperature dependence of the Raman spectra of salophen combined with thermal analysis invest...

The Schiff base of N,N′-Bis(Salicylidene)-p-Phenylenediamine (BSP) has been synthesized and characterized. The molecular structure and spectroscopic properties of the compound were experimentally characterized by elemental analysis, 1H NMR, FT-IR, UV–Visible, fluorescent spectroscopic techniqu...

Direct transition metal-free arylation of benzene has been achieved using a combination of various aryl halides and N,N′-bis(salicylidene)ethylenediamine as a new ligand and catalyst. This facile one-pot reaction is reported as a new CH functionalization protocol for the synthesis of biaryls. I...

The herbicide 2,4-dichlorophenoxy acetic acid (2,4-D) induces a wide spectrum of toxic responses in living organisms. In this study, we analyzed the stress-induced responses of Corynebacterium glutamicum cells on protein level upon treatment with 2,4-D. For this, growing C. glutamicum cells were...

2-(2,4-Dichlorophenoxy)-N′-(2-hydroxybenzylidene)acetohydrazide (H2L) complexes were prepared by ball milling involving the reaction of ligand with Ni(II), Co(II), Cu(II) and VO(II) salts (mechanochemical syntheses). The compounds were elucidated by elemental analysis, spectroscopy (1H NMR, IR,...

2,4-Dichlorophenoxy acetic acid (2,4-D) is a well-known plant auxin which is widely used in plant tissue culture experiments as well as a weed killer and a herbicide. In this study, 2,4-D was rediscovered as a new anti-inflammatory agent through an in silico molecular modeling and docking studie...

The use of inexpensive semiconducting materials and abundant natural sunlight can deliver the sustainable as well as cost-effective cleaning of contaminated water. In the current effort, the low photocatalytic activity of ZnO in sunlight exposure has been addressed by the slow deposition and aft...

The synthesis and characterization of novel nitrile compound (3) and peripherally tetra 5-chloro-2-(2,4-dichlorophenoxy)phenol substituted nickel(II) (4), iron(II) (5) and copper(II) (6) phthalocyanines were accomplished for the first time in this study. Electrochemical characterizations of the ...

In this study, novel peripherally tetra-(5-chloro-2-(2,4-dichlorophenoxy)phenol) substituted metal-free (4), zinc(II) (5) and lead(II) (6) phthalocyanine derivatives were synthesised. The novel phthalocyanines (4–6) were characterised by general spectroscopic methods such as IR, 1H NMR, UV–vis...

Phenacetin, N-methylacetanilide and N-ethylacetanilide prevented N-2-fluorenylacetamide hepatocarcinogenesis in F344 strain rats. Phenacetin was most effective followed by N-ethylacetanilide. Phenacetin was not carcinogenic when fed at 0.8% level for 16 weeks followed by control diet for another...

Flash vacuum pyrolysis (FVP) of 3-oxo-2-arylhydrazonopropanals at 500°C and 0.02 Torr yielded the corresponding derivatives of anilines, N-formylanilines, N-benzoylanilines and benzoylnitriles. Similar FVP of phenylhydrazonomalononitrile, phenylhydrazonoacetylacetone and phenylhydrazono ethyl c...

The reaction of oligomerization ofphenylglycidyl ether on exposure to 2-dimethylaminomethylphenol at 120°C has been studied. Mass spectroscopy, GPC and GLC, IR spectroscopy and elemental analysis were used to identify the oligomerization products and evaluate their molecular mass characteristic...

Mouse, human, and E. coli methionine sulfoxide reductase A (MSRA) stereospecifically catalyze both the reduction of S-methionine sulfoxide to methionine and the oxidation of methionine to S-methionine sulfoxide. Calmodulin has 9 methionine residues, but only Met77 is oxidized by MSRA, and this i...

Dimethyl sulfoxide (DMSO) is widely used in industrial, medical, and other applications. However, it has been demonstrated that DMSO is toxic at low concentrations. Therefore, it is important to find a way to trap/reduce it. It has been shown that two dimensional materials can be used for enviro...

Dimethyl sulfoxide (DMSO) is an excellent organic solvent, and widely used in laboratories and industries. Therefore, plenty amount of wastewater containing DMSO have been discharged. As the DMSO is high resistant to biological process which is mostly used for wastewater treatments, other strong...

Chiral sulfoxides are widely used in organic synthesis as chiral auxiliaries. There are numerous strategies for the preparation of enantiomerically pure sulfoxides, based either on the enantioselective oxidation of sulphides or the enantiospecific reduction of sulfoxides. For both cases, bioconv...

Methionine sulfoxide reductase enzymes are a protective system against biological oxidative stress in aerobic organisms. Modifications to this antioxidant system have been shown to impact the lifespan of several model system organisms. In humans, methionine oxidation of critical proteins and def...