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Wuhan Zenuo Biological Medicine Technology Co Ltd

Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detect

Bifonazole Manufactuered in China

Cas:60628-96-8

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Bifonazole Cas 60628-96-8 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white crystalline powder Storage:Store at RT Package:25

Factory supply Bifonazole Cas 60628-96-8 with high quality and favorable price

Cas:60628-96-8

Min.Order:1 Kilogram

FOB Price: $100.0 / 114.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Bifonazole

Cas:60628-96-8

Min.Order:1

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Bifonazole manufacturer with low price

Cas:60628-96-8

Min.Order:1 Gram

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Bifonazole 60628-96-8 GMP Manufacturer

Cas:60628-96-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

Bifonazole TOP1 supplier in China

Cas:60628-96-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Bifonazole

Cas:60628-96-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:bifonazole CAS NO: 60628-96-8 Grade:Medical scientific research and export Molecular formula:C22H18N2 Molecular weight:310.3917 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data

bifonazole/cas:60628-96-8/Raw material spot

Cas:60628-96-8

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM -Bifonazole

Cas:60628-96-8

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Bifonazole

Cas:60628-96-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top CAS 60628-96-8 with high-quality service

Cas:60628-96-8

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Bifonazole

Cas:60628-96-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Bifonazole CAS60628-96-8

Cas:60628-96-8

Min.Order:1 Kilogram

FOB Price: $5.0 / 9.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: Bifonazole Synonyms: mycospor;bifonazol CAS: 60628-96-8 MF: C22H18N2 MW: 310.39 EINECS: 262-336-6 Purity:99% Appearance:White crystalline powder Appearance: white powder Storage:Store in cool and dry place, away from sun ligh

Bifonazole CAS: 60628-96-8

Cas:60628-96-8

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Powder Storage:Store in sealed containers at cool & dry pla

High Purity Pharmaceutical Raw Powder Bifonazole CAS 60628-96-8

Cas:60628-96-8

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermed

Supplier Bifonazole99% with lower price

Cas:60628-96-8

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

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Hefei TNJ chemical industry co.,ltd

1. One of the domestic largest manufacturers of API; 2. High quality,competitive price and delivery in time; 3. Supplier of safe and ecofriendly products ; 4. Stable supply and efficient service; 5. Cooperate with scientific

Manufacturer of Bifonazole at Factory Price

Cas:60628-96-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Antibacterial drugs Bifonazole with CAS:60628-96-8

Cas:60628-96-8

Min.Order:500 Gram

FOB Price: $41.0 / 55.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Bifonazole CAS:60628-96-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Bifonazole CAS:60628-96-8

Cas:60628-96-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Bifonazole CAS NO.60628-96-8

Cas:60628-96-8

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Wuhan Kemi-Works Chemical Co., Ltd

1.Product name: Bifonazole 2.CAS No. 60628-96-8 3.Standard: CP2005, BP2000 4.Assay: 98% min. 1.We have been specializing in special fine chemical for long, with strong R&D strength. 2.ISO9001. 3.We have been cooperating with oversea fr

Bifonazole

Cas:60628-96-8

Min.Order:10 Kilogram

Negotiable

Type:Other

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Hebei Mojin Biotechnology Co.,Ltd

Company information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in carbomer,carbopol,lead acetate,meglumine diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterpr

CAS 60628-96-8 powder Bifonazole

Cas:60628-96-8

Min.Order:1 Kilogram

FOB Price: $138.0 / 150.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:60628-96-8

Cas:60628-96-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Lonwin Chemical Group Limited

Lonwin Industry Group Limited. Lonwin Industry group limited as a professional manufactor & exporter of chemical materials ,we totally have more than 270 stuffs, we have been on this line for more than 9 years. Our chemical materials are expo

Factory Supply High Quality Bifonazole Powder CAS 60628-96-8

Cas:60628-96-8

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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DB BIOTECH CO., LTD

Q1: Are you a manufacturer?Answer: Yes, we are factory founded on 2002. Q2: How to contact with us?Click "contact supplier" And then send us message the product you interest in, you will get reply within 12 hours. Q3:Which kind of payment terms do yo

Bifonazole

Cas:60628-96-8

Min.Order:0

Negotiable

Type:Trading Company

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Bifonazole

Cas:60628-96-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Bifonazole

Cas:60628-96-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Bifonazole

Cas:60628-96-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Bifonazole CAS NO.60628-96-8

Cas:60628-96-8

Min.Order:10 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:antibacterial Transportation:BY SEA Port:Sha

Bifonazole

Cas:60628-96-8

Min.Order:1 Metric Ton

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Synthetic route

(R,S)-1-<α-(4-Biphenylyl)benzyl>imidazole-4,5-dicarboxylic acid
162824-42-2

(R,S)-1-<α-(4-Biphenylyl)benzyl>imidazole-4,5-dicarboxylic acid

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
In diphenylether for 0.5h; Heating;98%
1H-imidazole
288-32-4

1H-imidazole

4-benzylbiphenyl
613-42-3

4-benzylbiphenyl

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Stage #1: 4-benzylbiphenyl With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane for 0.833333h; Inert atmosphere; Reflux;
Stage #2: 1H-imidazole With potassium carbonate In acetonitrile for 1h; Reflux;
77%
Stage #1: 4-benzylbiphenyl With pyridine; tert.-butylhydroperoxide; iodine In decane; water at 80℃; for 12h; Schlenk technique; Inert atmosphere;
Stage #2: 1H-imidazole With formic acid; toluene-4-sulfonic acid In water at 180 - 200℃; for 10h; Schlenk technique; Inert atmosphere;
66%
1H-imidazole
288-32-4

1H-imidazole

C26H21N2O2S(1-)*Na(1+)

C26H21N2O2S(1-)*Na(1+)

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
With copper acetylacetonate; tetrabutylammomium bromide In toluene at 85℃; for 36h;52%
4-phenylbenzhydrol
7598-80-3

4-phenylbenzhydrol

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
In 1-methyl-pyrrolidin-2-one Heating;12%
phenylmagnesium bromide

phenylmagnesium bromide

1-[(4-methoxy-phenyl)-phenyl-methyl]-1H-imidazole

1-[(4-methoxy-phenyl)-phenyl-methyl]-1H-imidazole

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
With bis(dicyclohexylphenylphosphine)nickel(II) chloride In diethyl ether at 80℃; for 15h;
4-phenylbenzhydrol
7598-80-3

4-phenylbenzhydrol

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 96 percent / DEAD, Ph3P / tetrahydrofuran / 24 h / Ambient temperature
2: 85 percent / NaOH / ethanol / 24 h / Heating
3: 98 percent / diphenyl ether / 0.5 h / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 °C / Inert atmosphere
2.2: 0 - 100 °C / Inert atmosphere
View Scheme
1-<α-(4-Biphenylyl)benzyl>imidazole-4,5-dicarbonitrile
162824-36-4

1-<α-(4-Biphenylyl)benzyl>imidazole-4,5-dicarbonitrile

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / NaOH / ethanol / 24 h / Heating
2: 98 percent / diphenyl ether / 0.5 h / Heating
View Scheme
4-(chlorophenylmethyl)-1,1'-biphenyl
7515-73-3

4-(chlorophenylmethyl)-1,1'-biphenyl

1-(Trimethylsilyl)imidazole
18156-74-6

1-(Trimethylsilyl)imidazole

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
In acetonitrile
1H-imidazole
288-32-4

1H-imidazole

4-phenylbenzhydrol
7598-80-3

4-phenylbenzhydrol

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Stage #1: 1H-imidazole; 4-phenylbenzhydrol With ammonium bromide In water at 125 - 130℃; for 2h; Industrial scale;
Stage #2: With ammonium bromide In water at 190 - 195℃; for 2h; Temperature; Industrial scale;
trimethylphenylsilane
768-32-1

trimethylphenylsilane

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: silver(I) 4-methylbenzenesulfonate; dichloro(N-(diphenylphosphino)-N-isopropyl-1,1-diphenylphosphinamine) digold(I); [bis(acetoxy)iodo]benzene / 1,1,1-trichloroethane / 2 h / 110 °C / Inert atmosphere; Schlenk technique
2.1: aluminum oxide; sodium tetrahydroborate / ethanol / 0.67 h / 20 °C / Inert atmosphere
3.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 °C / Inert atmosphere
4.2: 0 - 100 °C / Inert atmosphere
View Scheme
(4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)(phenyl)methanone
1063965-82-1

(4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)(phenyl)methanone

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: silver(I) 4-methylbenzenesulfonate; dichloro(N-(diphenylphosphino)-N-isopropyl-1,1-diphenylphosphinamine) digold(I); [bis(acetoxy)iodo]benzene / 1,1,1-trichloroethane / 2 h / 110 °C / Inert atmosphere; Schlenk technique
2.1: aluminum oxide; sodium tetrahydroborate / ethanol / 0.67 h / 20 °C / Inert atmosphere
3.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 °C / Inert atmosphere
4.2: 0 - 100 °C / Inert atmosphere
View Scheme
biphenyl-4-yl-phenyl-methanone
2128-93-0

biphenyl-4-yl-phenyl-methanone

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aluminum oxide; sodium tetrahydroborate / ethanol / 0.67 h / 20 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 °C / Inert atmosphere
3.2: 0 - 100 °C / Inert atmosphere
View Scheme
1H-imidazole
288-32-4

1H-imidazole

[1,1'-biphenyl]-4-yl(phenyl)methyl methanesulfonate

[1,1'-biphenyl]-4-yl(phenyl)methyl methanesulfonate

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Stage #1: 1H-imidazole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 2h; Inert atmosphere;
Stage #2: [1,1'-biphenyl]-4-yl(phenyl)methyl methanesulfonate In N,N-dimethyl-formamide; mineral oil at 0 - 100℃; Inert atmosphere;
61.9 mg
Diphenylmethane
101-81-5

Diphenylmethane

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dichloromethane / -40 - 20 °C / Schlenk technique; Inert atmosphere
2: bis(tri-t-butylphosphine)palladium(0); sodium hydrogencarbonate / dichloromethane; N,N-dimethyl-formamide / 12 h / 50 °C / Inert atmosphere; Schlenk technique
3: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / 0.83 h / Inert atmosphere; Reflux
4: potassium carbonate / acetonitrile / 1 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: dichloromethane / -40 - 20 °C / Inert atmosphere; Schlenk technique
2.1: sodium hydrogencarbonate; bis(tri-t-butylphosphine)palladium(0) / dichloromethane; N,N-dimethyl-formamide / 12 h / 50 °C / Inert atmosphere; Schlenk technique; Sealed tube
3.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 0.83 h / Inert atmosphere; Reflux
3.2: 1 h / Reflux
View Scheme
C25H19S2(1+)*CF3O3S(1-)

C25H19S2(1+)*CF3O3S(1-)

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: bis(tri-t-butylphosphine)palladium(0); sodium hydrogencarbonate / dichloromethane; N,N-dimethyl-formamide / 12 h / 50 °C / Inert atmosphere; Schlenk technique
2: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / 0.83 h / Inert atmosphere; Reflux
3: potassium carbonate / acetonitrile / 1 h / Reflux
View Scheme
1H-imidazole
288-32-4

1H-imidazole

4-phenyl-benzhydryl bromide
60047-92-9

4-phenyl-benzhydryl bromide

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 1h; Reflux;47.9 mg
4-benzylbiphenyl
613-42-3

4-benzylbiphenyl

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / 0.83 h / Inert atmosphere; Reflux
2: potassium carbonate / acetonitrile / 1 h / Reflux
View Scheme
2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole
24388-23-6

2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole

C25H19S2(1+)*CF3O3S(1-)

C25H19S2(1+)*CF3O3S(1-)

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydrogencarbonate; bis(tri-t-butylphosphine)palladium(0) / dichloromethane; N,N-dimethyl-formamide / 12 h / 50 °C / Inert atmosphere; Schlenk technique; Sealed tube
2.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 0.83 h / Inert atmosphere; Reflux
2.2: 1 h / Reflux
View Scheme
N-trifluoromethanesulfony-4-benzylaniline

N-trifluoromethanesulfony-4-benzylaniline

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tetrahydrofuran / 0.08 h / 20 °C / Schlenk technique; Inert atmosphere
1.2: 12.03 h / 70 °C / Schlenk technique; Inert atmosphere; Glovebox
2.1: iodine; pyridine; tert.-butylhydroperoxide / water; decane / 12 h / 80 °C / Schlenk technique; Inert atmosphere
2.2: 10 h / 180 - 200 °C / Schlenk technique; Inert atmosphere
View Scheme
p-benzylaniline
1135-12-2

p-benzylaniline

bifonazole
60628-96-8

bifonazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 12.5 h / -78 - 20 °C / Schlenk technique; Inert atmosphere
2.1: tetrahydrofuran / 0.08 h / 20 °C / Schlenk technique; Inert atmosphere
2.2: 12.03 h / 70 °C / Schlenk technique; Inert atmosphere; Glovebox
3.1: iodine; pyridine; tert.-butylhydroperoxide / water; decane / 12 h / 80 °C / Schlenk technique; Inert atmosphere
3.2: 10 h / 180 - 200 °C / Schlenk technique; Inert atmosphere
View Scheme
tetrafluoroboric acid diethyl ether
67969-82-8

tetrafluoroboric acid diethyl ether

sodium tetrafluoroborate
13755-29-8

sodium tetrafluoroborate

thianthrene-5-oxide
2362-50-7

thianthrene-5-oxide

bifonazole
60628-96-8

bifonazole

C34H25N2S2(1+)*BF4(1-)

C34H25N2S2(1+)*BF4(1-)

Conditions
ConditionsYield
Stage #1: tetrafluoroboric acid diethyl ether; thianthrene-5-oxide; bifonazole With trifluoroacetic anhydride In acetonitrile at 0 - 25℃; for 18h; Schlenk technique;
Stage #2: sodium tetrafluoroborate In dichloromethane; water
95%
Ethyl 4-bromobenzoate
5798-75-4

Ethyl 4-bromobenzoate

bifonazole
60628-96-8

bifonazole

ethyl 4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzoate

ethyl 4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzoate

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;90%
2,3,7,8-tetrafluorothianthrene-S-oxide

2,3,7,8-tetrafluorothianthrene-S-oxide

bifonazole
60628-96-8

bifonazole

C34H21F4N2S2(1+)

C34H21F4N2S2(1+)

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; 2,3,7,8-tetrafluorothianthrene; trifluoroacetic anhydride In acetonitrile at 0 - 25℃; regioselective reaction;87%
trifluorormethanesulfonic acid
1493-13-6

trifluorormethanesulfonic acid

2,3,7,8-tetrafluorothianthrene-S-oxide

2,3,7,8-tetrafluorothianthrene-S-oxide

sodium triflate
2926-30-9

sodium triflate

bifonazole
60628-96-8

bifonazole

C34H21F4N2S2(1+)*CF3O3S(1-)

C34H21F4N2S2(1+)*CF3O3S(1-)

Conditions
ConditionsYield
Stage #1: trifluorormethanesulfonic acid; 2,3,7,8-tetrafluorothianthrene-S-oxide; bifonazole With trifluoroacetic anhydride In acetonitrile at 0 - 25℃; for 3h; Sealed tube;
Stage #2: sodium triflate In ethanol; dichloromethane; water
87%
4'-Bromopropiophenone
10342-83-3

4'-Bromopropiophenone

bifonazole
60628-96-8

bifonazole

1-(4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)phenyl)propan-1-one

1-(4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)phenyl)propan-1-one

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;77%
4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

bifonazole
60628-96-8

bifonazole

4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzaldehyde

4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzaldehyde

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;77%
3-bromo-1-trifluoromethylbenzene
401-78-5

3-bromo-1-trifluoromethylbenzene

bifonazole
60628-96-8

bifonazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(3-(trifluoromethyl)phenyl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(3-(trifluoromethyl)phenyl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;71%
p-trifluoromethylphenyl bromide
402-43-7

p-trifluoromethylphenyl bromide

bifonazole
60628-96-8

bifonazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-(trifluoromethyl)phenyl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-(trifluoromethyl)phenyl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;66%
Dibenzothiophene sulfoxide
1013-23-6

Dibenzothiophene sulfoxide

trifluorormethanesulfonic acid
1493-13-6

trifluorormethanesulfonic acid

bifonazole
60628-96-8

bifonazole

C34H25N2S(1+)*CF3O3S(1-)

C34H25N2S(1+)*CF3O3S(1-)

Conditions
ConditionsYield
With trifluoroacetic anhydride In acetonitrile at -40 - 25℃; for 2h; Schlenk technique; Glovebox; Inert atmosphere;65%
4-bromoisoquinoline
1532-97-4

4-bromoisoquinoline

bifonazole
60628-96-8

bifonazole

4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)isoquinoline

4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)isoquinoline

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;63%
4-bromobenzenecarbonitrile
623-00-7

4-bromobenzenecarbonitrile

bifonazole
60628-96-8

bifonazole

4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)-benzonitrile

4-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)-benzonitrile

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;61%
3-cyanobromobenzene
6952-59-6

3-cyanobromobenzene

bifonazole
60628-96-8

bifonazole

3-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzonitrile

3-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzonitrile

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;61%
2-Acetyl-5-bromothiophene
5370-25-2

2-Acetyl-5-bromothiophene

bifonazole
60628-96-8

bifonazole

1-(5-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)thiophen-2-yl)ethan-1-one

1-(5-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)thiophen-2-yl)ethan-1-one

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;59%
o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

bifonazole
60628-96-8

bifonazole

2-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzonitrile

2-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)benzonitrile

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;58%
para-bromotoluene
106-38-7

para-bromotoluene

bifonazole
60628-96-8

bifonazole

A

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-2,5-di-p-tolyl-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-2,5-di-p-tolyl-1H-imidazole

B

C29H24N2

C29H24N2

Conditions
ConditionsYield
With cesium acetate; palladium diacetate at 150℃; for 48h; Inert atmosphere; Schlenk technique;A 58%
B n/a
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

bifonazole
60628-96-8

bifonazole

A

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-2,5-bis(4-methoxyphenyl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-2,5-bis(4-methoxyphenyl)-1H-imidazole

B

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-methoxyphenyl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-methoxyphenyl)-1H-imidazole

Conditions
ConditionsYield
With cesium acetate; palladium diacetate at 150℃; for 48h; Inert atmosphere; Schlenk technique;A 57%
B n/a
bromobenzene
108-86-1

bromobenzene

bifonazole
60628-96-8

bifonazole

A

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-2,5-diphenyl-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-2,5-diphenyl-1H-imidazole

B

C28H22N2

C28H22N2

Conditions
ConditionsYield
With cesium acetate; palladium diacetate at 150℃; for 48h; Inert atmosphere; Schlenk technique;A 55%
B n/a
[(Co(C20H8N4(C6H5)3(C6H4CONH2)))2]

[(Co(C20H8N4(C6H5)3(C6H4CONH2)))2]

bifonazole
60628-96-8

bifonazole

Co(O(C4NH2C(C6H5))3H(OH)C4NH2C6H4C2NO)(bifonazole)

Co(O(C4NH2C(C6H5))3H(OH)C4NH2C6H4C2NO)(bifonazole)

Conditions
ConditionsYield
With air In chloroform treatment of Co-complex with rac-bifonazole; XRD, UV-Vis;46%
o-trifluoromethylphenyl bromide
392-83-6

o-trifluoromethylphenyl bromide

bifonazole
60628-96-8

bifonazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(2-(trifluoromethyl)phenyl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(2-(trifluoromethyl)phenyl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;45%
3-Chloropyridine
626-60-8

3-Chloropyridine

bifonazole
60628-96-8

bifonazole

3-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)pyridine

3-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)pyridine

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;45%
bifonazole
60628-96-8

bifonazole

para-nitrophenyl bromide
586-78-7

para-nitrophenyl bromide

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-nitrophenyl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-nitrophenyl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;43%
1-Bromonaphthalene
90-11-9

1-Bromonaphthalene

bifonazole
60628-96-8

bifonazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(naphthalen-1-yl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(naphthalen-1-yl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;42%
5-bromopyrimidine
4595-59-9

5-bromopyrimidine

bifonazole
60628-96-8

bifonazole

5-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)pyrimidine

5-(1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-1H-imidazol-5-yl)pyrimidine

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;41%
2-bromonaphthalene
580-13-2

2-bromonaphthalene

bifonazole
60628-96-8

bifonazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(naphthalen-2-yl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(naphthalen-2-yl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;39%
1-bromo-4-tert-butylbenzene
3972-65-4

1-bromo-4-tert-butylbenzene

bifonazole
60628-96-8

bifonazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-(tert-butyl)-phenyl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(4-(tert-butyl)-phenyl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;34%
1,2-(methylenedioxy)-4-bromobenzene
2635-13-4

1,2-(methylenedioxy)-4-bromobenzene

bifonazole
60628-96-8

bifonazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(benzo[d][1,3]-dioxol-5-yl)-1H-imidazole

1-([1,1′-biphenyl]-4-yl(phenyl)methyl)-5-(benzo[d][1,3]-dioxol-5-yl)-1H-imidazole

Conditions
ConditionsYield
With potassium acetate; palladium diacetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;28%
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