Product Name

  • Name

    (R)-(-)-2-Pentanol

  • EINECS 256-810-1
  • CAS No. 31087-44-2
  • Article Data73
  • CAS DataBase
  • Density 0.809 g/cm3
  • Solubility
  • Melting Point -51.44°C (estimate)
  • Formula C5H12O
  • Boiling Point 118.8 °C at 760 mmHg
  • Molecular Weight 88.1497
  • Flash Point 33.9 °C
  • Transport Information UN 1105 3/PG 3
  • Appearance Colorless to light yellow liquid
  • Safety 24/25
  • Risk Codes 10-20
  • Molecular Structure Molecular Structure of 31087-44-2 ((R)-(-)-2-Pentanol)
  • Hazard Symbols HarmfulXn
  • Synonyms (R)-2-Pentanol;
  • PSA 20.23000
  • LogP 1.16730

Synthetic route

2-Pentanone
107-87-9

2-Pentanone

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With hydrogen; C19H29B10ClNORh In ethanol at 80℃; under 760.051 Torr; for 1h;92%
With glucose dehydrogenase; ketoreductase Kred-107; glucose; NADPH for 24h; Enzymatic reaction; optical yield given as %ee; stereoselective reaction;89%
With Leifsonia sp. S749 cells alcohol dehydrogenase; nicotinamide adenine dinucleotide; isopropyl alcohol In phosphate buffer at 25℃; for 24h; pH=7.0;17%
2-Pentanone
107-87-9

2-Pentanone

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
SADH from Thermoanaerobacter ethanolicus at 37℃; Product distribution; enantiospecificity in enzymatic reaction; var. temp.;
With secondary alcohol dehydrogenase of Thermoanaerobacter ethanolicus,Tris buffer; NADP In isopropyl alcohol at 37℃; for 10h; Rate constant; Product distribution; different coenzymes: effect of the coenzyme on the enantioselectivity of alcohol dehydrogenase; other temp.;
With mercaptoethyl alcohol; Tris-HCl buffer; alcohol dehydrogenase from Thermoanaerobium brockii; NADP; isopropyl alcohol In water at 22℃; for 5h; Mechanism; various buffers; effect of pH, reaction time, temperature, concentration of substrate and of 2-propanol; also with growing cells; also with enzyme immobilized on different supports: effect of contact time and of concentration of NADP;
C20H37N2O2(1+)*F6P(1-)

C20H37N2O2(1+)*F6P(1-)

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With potassium hydroxide In methanol at 50℃; for 0.5h;
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

A

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

B

2-Pentanone
107-87-9

2-Pentanone

Conditions
ConditionsYield
With lyophilized cells of Rhodococcus ruber DSM 44541; acetone In phosphate buffer at 24℃; for 24h; pH=8.0; Enzyme kinetics;
With lyophilized cells of Rhodococcus ruber DSM 44541; acetone In phosphate buffer at 24℃; for 24h; pH=8.0; Title compound not separated from byproducts.;
Stage #1: (+/-)-2-pentanol With potassium bromide In water at 25℃; for 0.166667h; Resolution of racemate;
Stage #2: With [bis(acetoxy)iodo]benzene In water at 25℃; for 2h; enantioselective reaction;
A n/a
B n/a
With wild type flavoprotein alcohol oxidase from Phanerochaete chrysosporium In aq. phosphate buffer at 35℃; for 24h; pH=7.5; Kinetics; enantioselective reaction;A n/a
B n/a
vinyl acetate
108-05-4

vinyl acetate

(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-pentan-2-yl acetate
54638-10-7

(R)-pentan-2-yl acetate

D

(S)-pentan-2-yl acetate

(S)-pentan-2-yl acetate

Conditions
ConditionsYield
With Escherichia coli BioH In hexane at 35℃; for 28h; Resolution of racemate; optical yield given as %ee; enantioselective reaction;
With immobilized LipG9 In hexane at 35℃; for 24h; Solvent; Temperature; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
C n/a
D n/a
(R)-benzoic acid 1-methylbutyl ester
39180-02-4, 102245-25-0, 102339-78-6

(R)-benzoic acid 1-methylbutyl ester

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With potassium hydroxide In tetrahydrofuran; methanol; water at 25℃; for 2h;93.5%
(R)-1-methylbutyl n-octanoate

(R)-1-methylbutyl n-octanoate

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With water; sodium hydroxide at 41 - 75℃; for 17.5h; Temperature;
(R)-1-methylbutyl n-octanoate

(R)-1-methylbutyl n-octanoate

A

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

B

Octanoic acid
124-07-2

Octanoic acid

Conditions
ConditionsYield
With water; sodium hydroxide at 41 - 75℃; for 17.5h;
2-Pentyl acetate
626-38-0

2-Pentyl acetate

A

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

B

(S)-pentan-2-yl acetate

(S)-pentan-2-yl acetate

Conditions
ConditionsYield
With Candida antarctica lipase B wild-type (WT); water In aq. phosphate buffer; acetonitrile at 37℃; for 5h; pH=7.5; Reagent/catalyst; Resolution of racemate; enantioselective reaction;A 40%
B n/a
With phosphate buffer; immobilized lipase PS In methanol at 30℃; pH=7.0;
With Candida antarctica lipase B immobilized on acrylic resin catalyst at 20 - 25℃; for 8h; pH=7.4; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;
Octanoic acid
124-07-2

Octanoic acid

(R)-1-methylbutyl n-octanoate

(R)-1-methylbutyl n-octanoate

A

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

B

sodium caprylate
1984-06-1

sodium caprylate

Conditions
ConditionsYield
With water; sodium hydrogencarbonate at 37℃; pH=8 - 8.5; Reagent/catalyst; Time; Green chemistry; Enzymatic reaction;
pentane
109-66-0

pentane

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

pentan-1-ol
71-41-0

pentan-1-ol

Conditions
ConditionsYield
With 1,4-dihydronicotinamide adenine dinucleotide; PIPES buffer; particulate methane monooxygenase In water at 45℃; pH=7.3; Kinetics; Oxidation;
With Durohydroquinone; ammonia monooxygenase of nitrosomonas europaea In aq. phosphate buffer at 30℃; under 760.051 Torr; for 0.166667h; Reagent/catalyst; regioselective reaction;A n/a
B n/a
C n/a
With Durohydroquinone; methylosinus trichosporium OB3b In aq. phosphate buffer at 30℃; under 760.051 Torr; for 0.166667h; Reagent/catalyst; enantioselective reaction;A n/a
B n/a
C n/a
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

2-Pentanone
107-87-9

2-Pentanone

Conditions
ConditionsYield
With whole lyophilised cells of Rhodococcus ruber DSM; acetone In phosphate buffer at 30℃; for 38h; pH=8.0;
With [bis(acetoxy)iodo]benzene; potassium bromide; (S,S)-chloro[2,2'-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis-[4,6-bis(1,1-dimethylethyl)phenolato]](2-)-N,N',O,O'-manganese In dichloromethane at 20℃; for 1h; Product distribution; Kinetics; Further Variations:; Solvents;
With [bis(acetoxy)iodo]benzene; potassium bromide In dichloromethane; water at 20℃; for 1h; Title compound not separated from byproducts.;
With NADP In acetone at 50℃; for 22h; pH=8; Resolution of racemate;
Stage #1: (+/-)-2-pentanol With 36Zn(2+)*6O(2-)*12C40H44O12S4(4-)*12Mn(3+)*12C30H34N2O6(4-)*21H2O*38C3H7NO In dichloromethane; water for 0.0833333h; Resolution of racemate;
Stage #2: With [bis(acetoxy)iodo]benzene; tetraethylammonium bromide In dichloromethane; water at 0℃; for 0.5h; Reagent/catalyst; Optical yield = 86 %ee; enantioselective reaction;
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With diphenic acid; (R,R)-1,2-diphenylethylenediamine In ethanol Title compound not separated from byproducts;
With C13H14N2*C18H14O8 In water; acetonitrile at 20℃; Resolution of racemate; optical yield given as %ee; enantioselective reaction;
With homochiral metal-organic cage [Zn3(deprotonated [3+3] macrocyclic Schiff base of trans-1,2-diaminocyclohexane and 4-tert-butyl-2,6-diformylphenol)2] coated capillary column In dichloromethane at 75℃; Reagent/catalyst; Temperature; Resolution of racemate; enantioselective reaction;
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With sulfuric acid; (3R,4R)-1-phenyl-3,4-dihydroxy-2,5-dioxopyrrolidine und Verseifen des durch Umkrystallisieren aus Isopropylalkohol erhaltenen (+)-Tartranilsaeureesters;
With phthalic anhydride Veresterung, Spaltung des sauren Phthalats mit Brucin und Verseifung;
ueber N2-<(R)-1-Methyl-butoxycarbonyl>-L-asparagin;
(1R)-1-Methylbutyl dodecanoate
140390-73-4

(1R)-1-Methylbutyl dodecanoate

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In diethyl ether for 2h; Heating;20%
2-Pentanol 3,5-dinitrobenzoate ester
10574-10-4

2-Pentanol 3,5-dinitrobenzoate ester

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran at 20℃; for 5h; Hydrolysis;
Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. NaOH
2: aq. NaOH / ethanol
3: H2 / PtO2
View Scheme
phthalic acid mono-((R)-1-methyl-but-2-ynyl) ester
57984-71-1

phthalic acid mono-((R)-1-methyl-but-2-ynyl) ester

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. NaOH / ethanol
2: H2 / PtO2
View Scheme
(R)-pent-4-en-2-ol
64584-92-5

(R)-pent-4-en-2-ol

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With hydrogen; platinum on activated charcoal
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

(S)-threonyl-(S)-phenylglycine
844641-16-3

(S)-threonyl-(S)-phenylglycine

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

C5H12O*C12H16N2O4

C5H12O*C12H16N2O4

D

C5H12O*C12H16N2O4
1296868-06-8

C5H12O*C12H16N2O4

Conditions
ConditionsYield
for 0.5h; Resolution of racemate; optical yield given as %ee;
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

Octanoic acid
124-07-2

Octanoic acid

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-1-methylbutyl n-octanoate

(R)-1-methylbutyl n-octanoate

Conditions
ConditionsYield
With Candida antarctica lipase B immobilized on acrylic resin catalyst In pentane at 20 - 25℃; for 24h; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 1.4 g
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

acetic acid
64-19-7

acetic acid

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-pentan-2-yl acetate
54638-10-7

(R)-pentan-2-yl acetate

Conditions
ConditionsYield
With Candida antarctica lipase B immobilized on acrylic resin catalyst In pentane at 20 - 25℃; for 24h; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 0.81 g
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

hexanoic acid
142-62-1

hexanoic acid

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-2-pentyl hexanoate
117636-54-1

(R)-2-pentyl hexanoate

Conditions
ConditionsYield
With Candida antarctica lipase B immobilized on acrylic resin catalyst In pentane at 20 - 25℃; for 24h; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 1.21 g
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

butyric acid
107-92-6

butyric acid

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-2-pentyl butanoate
117636-44-9

(R)-2-pentyl butanoate

Conditions
ConditionsYield
With Candida antarctica lipase B immobilized on acrylic resin catalyst In pentane at 20 - 25℃; for 24h; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 1.02 g
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

acetic acid
64-19-7

acetic acid

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-pentan-2-yl acetate
54638-10-7

(R)-pentan-2-yl acetate

D

(S)-pentan-2-yl acetate

(S)-pentan-2-yl acetate

Conditions
ConditionsYield
With Candida antarctica lipase B catalyst In n-heptane at 20 - 25℃; for 24h; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

hexanoic acid
142-62-1

hexanoic acid

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-2-pentyl hexanoate
117636-54-1

(R)-2-pentyl hexanoate

D

(S)-2-pentyl hexanoate
117636-48-3

(S)-2-pentyl hexanoate

Conditions
ConditionsYield
With Candida antarctica lipase B catalyst In n-heptane at 20 - 25℃; for 24h; Enzymatic reaction; optical yield given as %ee; enantioselective reaction;
Isopropenyl acetate
108-22-5

Isopropenyl acetate

(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-pentan-2-yl acetate
54638-10-7

(R)-pentan-2-yl acetate

D

(S)-pentan-2-yl acetate

(S)-pentan-2-yl acetate

Conditions
ConditionsYield
With immobilized LipG9 In hexane at 35℃; for 24h; Resolution of racemate; Enzymatic reaction;
(+/-)-2-pentanol
6032-29-7

(+/-)-2-pentanol

ethyl acetate
141-78-6

ethyl acetate

A

(S)-2-pentanol
26184-62-3

(S)-2-pentanol

B

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

C

(R)-pentan-2-yl acetate
54638-10-7

(R)-pentan-2-yl acetate

D

(S)-pentan-2-yl acetate

(S)-pentan-2-yl acetate

Conditions
ConditionsYield
With immobilized LipG9 In hexane at 35℃; for 24h; Resolution of racemate; Enzymatic reaction;
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide
levorotatory penten-(1)-ol-(4)

levorotatory penten-(1)-ol-(4)

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

Conditions
ConditionsYield
With diethyl ether; colloid; palladium Hydrogenation;
5-bromo-2-chloropyridine
53939-30-3

5-bromo-2-chloropyridine

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

5-bromo-2-((R)-1-methylbutoxy)pyridine

5-bromo-2-((R)-1-methylbutoxy)pyridine

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran; mineral oil at 80℃; for 1h; Solvent; Temperature; Inert atmosphere;100%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

4,7-dibromo-5,6-bis(bromomethyl)benzo[c][1,2,5]thiadiazole

4,7-dibromo-5,6-bis(bromomethyl)benzo[c][1,2,5]thiadiazole

C18H26Br2N2O2S

C18H26Br2N2O2S

Conditions
ConditionsYield
Stage #1: (R)-2-pentanol With ethylmagnesium bromide In tetrahydrofuran at 0 - 20℃; for 1.5h; Inert atmosphere;
Stage #2: 4,7-dibromo-5,6-bis(bromomethyl)benzo[c][1,2,5]thiadiazole In tetrahydrofuran at 20 - 80℃; for 12.5h; Inert atmosphere;
92%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

4-acetyloxy-benzoic acid
2345-34-8

4-acetyloxy-benzoic acid

benzylamine
100-46-9

benzylamine

4-hydroxy-1-(1-methylbutyloxycarbonyl)benzene

4-hydroxy-1-(1-methylbutyloxycarbonyl)benzene

Conditions
ConditionsYield
With pyridine; thionyl chloride In toluene86%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(R)-pentan-2-yl-4-methylbenzenesulfonate

(R)-pentan-2-yl-4-methylbenzenesulfonate

Conditions
ConditionsYield
With pyridine at 0℃; for 3h;84%
(E)-2-methyl-2-pentenoyl chloride
83841-91-2, 55764-37-9

(E)-2-methyl-2-pentenoyl chloride

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(E)-(R)-(1)-1-methylbutyl 2-methyl-2-pentenoate
140461-21-8

(E)-(R)-(1)-1-methylbutyl 2-methyl-2-pentenoate

Conditions
ConditionsYield
With pyridine In diethyl ether at 25℃; for 2h;77%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(R)-1-fluoroindan-1-carboxylic acid methyl ester
1467076-67-0

(R)-1-fluoroindan-1-carboxylic acid methyl ester

(R)-2-pentyl (R)-1-fluoroindan-1-carboxylate
1467076-72-7

(R)-2-pentyl (R)-1-fluoroindan-1-carboxylate

Conditions
ConditionsYield
Stage #1: (R)-2-pentanol With n-butyllithium In tetrahydrofuran; hexane at -5℃; for 0.5h; Inert atmosphere;
Stage #2: (R)-1-fluoroindan-1-carboxylic acid methyl ester In tetrahydrofuran; hexane for 0.25h; Inert atmosphere;
76%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(E)-2,4-Dimethyl-2-pentenoic acid chloride
89609-13-2

(E)-2,4-Dimethyl-2-pentenoic acid chloride

(R)-(-)-2'-pentyl (E)-2,4-dimethyl-2-pentenoate
140461-22-9

(R)-(-)-2'-pentyl (E)-2,4-dimethyl-2-pentenoate

Conditions
ConditionsYield
With pyridine In diethyl ether at 25℃; for 2h;73%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(S)-1-fluoroindan-1-carboxylic acid methyl ester
1467076-68-1

(S)-1-fluoroindan-1-carboxylic acid methyl ester

(R)-2-pentyl (S)-1-fluoroindan-1-carboxylate
1467076-73-8

(R)-2-pentyl (S)-1-fluoroindan-1-carboxylate

Conditions
ConditionsYield
Stage #1: (R)-2-pentanol With n-butyllithium In tetrahydrofuran; hexane at -5℃; for 0.5h; Inert atmosphere;
Stage #2: (S)-1-fluoroindan-1-carboxylic acid methyl ester In tetrahydrofuran; hexane for 0.25h; Inert atmosphere;
71%
2-chloropyrazin
14508-49-7

2-chloropyrazin

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

2-((R)-1-Methyl-butoxy)-pyrazine

2-((R)-1-Methyl-butoxy)-pyrazine

Conditions
ConditionsYield
With sodium hydride In 1,2-dimethoxyethane at 45℃; for 0.666667h;70%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

Methanesulfonic acid (R)-1-methyl-butyl ester
118106-70-0

Methanesulfonic acid (R)-1-methyl-butyl ester

Conditions
ConditionsYield
With pyridine at 0 - 20℃;69%
With pyridine69%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

p-trifluoromethylphenyl bromide
402-43-7

p-trifluoromethylphenyl bromide

(R)-1-(pentan-2-yloxy)-4-(trifluoromethyl)benzene

(R)-1-(pentan-2-yloxy)-4-(trifluoromethyl)benzene

Conditions
ConditionsYield
Stage #1: (R)-2-pentanol With tris[2-phenylpyridinato-C2,N]iridium(III); nickel(II) bromide dimethoxyethane; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.0833333h;
Stage #2: p-trifluoromethylphenyl bromide In N,N-dimethyl-formamide at 35℃; for 18h; Sealed tube; Irradiation;
69%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

triphenylene-2,3,6,7,10,11-hexacarboxylic acid hexaethyl ester
1402556-57-3

triphenylene-2,3,6,7,10,11-hexacarboxylic acid hexaethyl ester

C54H72O12

C54H72O12

Conditions
ConditionsYield
With 1-chloro-3-hydroxy-1,1,3,3-tetrabutyldistannoxane In toluene for 216h; Reflux; Inert atmosphere; Dean-Stark;65%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
53-86-1

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

indomethacin pentan‐2‐yl ester

indomethacin pentan‐2‐yl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 24h; Inert atmosphere;65%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

methyl 4-hydroxy-3-methylbenzoate
42113-13-3

methyl 4-hydroxy-3-methylbenzoate

methyl (S)-3-methyl-4-(pentan-2-yloxy)benzoate

methyl (S)-3-methyl-4-(pentan-2-yloxy)benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-hydroxy-3-methylbenzoate With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0℃; for 0.166667h; Mitsunobu Displacement;
Stage #2: (R)-2-pentanol In tetrahydrofuran at 0 - 20℃; for 20h; Mitsunobu Displacement;
64%
(1R,2S,5R)-1-(chloromethoxy)-2-isopropyl-5-methylcyclohexane
26127-08-2

(1R,2S,5R)-1-(chloromethoxy)-2-isopropyl-5-methylcyclohexane

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(2R,1'R,2'S,5'R)-2-(2-Isopropyl-5-methylcyclohexyloxymethoxy)pentane
94100-71-7

(2R,1'R,2'S,5'R)-2-(2-Isopropyl-5-methylcyclohexyloxymethoxy)pentane

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane 1) 0 deg C, 2 h, 2) r.t., 2 h;61%
With N-ethyl-N,N-diisopropylamine 1) 0 deg C, 2 h, 2) 20 deg C, 2 h;
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

2-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine
77111-77-4

2-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

6-amino-2-[(1R)-1-methylbutoxy]-9-(tetrahydro-2H-pyran-2-yl)-9H-purin
1050497-00-1

6-amino-2-[(1R)-1-methylbutoxy]-9-(tetrahydro-2H-pyran-2-yl)-9H-purin

Conditions
ConditionsYield
Stage #1: (R)-2-pentanol With sodium t-butanolate at 20℃; for 0.333333h;
Stage #2: 2-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine at 70℃; for 120h;
59%
With sodium t-butanolate at 50℃; for 160h;
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride
39637-99-5, 20445-33-4

(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

(R)-α-methoxy-α-(trifluoromethyl)phenylacetic acid (R)-2-pentyl ester

(R)-α-methoxy-α-(trifluoromethyl)phenylacetic acid (R)-2-pentyl ester

Conditions
ConditionsYield
With pyridine In dichloromethane52%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

2,4-dinitrobenzenesulfenyl chloride
528-76-7

2,4-dinitrobenzenesulfenyl chloride

(R)-2-pentyl 2,4-dinitrobenzenesulfenate

(R)-2-pentyl 2,4-dinitrobenzenesulfenate

Conditions
ConditionsYield
With pyridine In 1,2-dichloro-ethane for 0.5h; Ambient temperature;41.3%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(R)-methoxytrifluoromethylphenylacetyl chloride
20445-33-4, 39637-99-5

(R)-methoxytrifluoromethylphenylacetyl chloride

(S)-α-methoxy-α-(trifluoromethyl)phenylacetic acid (R)-2-pentyl ester

(S)-α-methoxy-α-(trifluoromethyl)phenylacetic acid (R)-2-pentyl ester

Conditions
ConditionsYield
With pyridine In dichloromethane41%
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(+)(S)-2-chloro-pentane
29882-57-3

(+)(S)-2-chloro-pentane

Conditions
ConditionsYield
With phosphorus trichloride
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(S)-2-bromopentane
29882-58-4

(S)-2-bromopentane

Conditions
ConditionsYield
With phosphorus tribromide at 0℃;
(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(S)-2-iodo-pentane
29882-59-5

(S)-2-iodo-pentane

Conditions
ConditionsYield
With carbon disulfide; phosphorous triiodide at 0℃;
With hydrogen iodide at 0℃; Erwaermen auf 55grad;
Methyl fluorosulfonate
421-20-5

Methyl fluorosulfonate

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(-)-(R)-2-methoxypentane
66585-43-1

(-)-(R)-2-methoxypentane

Conditions
ConditionsYield
In n-heptane
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

(R)-2-pentanol
31087-44-2

(R)-2-pentanol

(R)(-)(Pentyl-2-oxy)trimethylsilan
66585-29-3

(R)(-)(Pentyl-2-oxy)trimethylsilan

Conditions
ConditionsYield
With pyridine; 1,1,1,3,3,3-hexamethyl-disilazane

(R)-(-)-2-Pentanol Chemical Properties

Molecular Formula: C5H12O
Molar mass: 88.1482 g/mol
Density: 0.809 g/cm3
Flash Point: 33.9 °C
Index of Refraction: 1.405
Boiling Point: 118.8 °C at 760 mmHg
Vapour Pressure: 8.05 mmHg at 25 °C
Appearance: Colorless to light yellow liqui
Product categories of (R)-(-)-1-Phenyl-1,2-ethanediol (CAS NO.31087-44-2): Chiral Compounds;Alcohols, Hydroxy Esters and Derivatives;chiral;API intermediates;Chiral Building Blocks;Chiral Compounds;Functional Materials;Synthetic Organic Chemistry;Simple Alcohols (Chiral);Alcohols;Organic Building Blocks
Structure of (R)-(-)-1-Phenyl-1,2-ethanediol (CAS NO.31087-44-2):
            
XLogP3-AA: 1.2
H-Bond Donor: 1
H-Bond Acceptor: 1
IUPAC Name: Pentan-2-ol
Canonical SMILES: CCCC(C)O
InChI: InChI=1S/C5H12O/c1-3-4-5(2)6/h5-6H,3-4H2,1-2H3 
InChIKey: JYVLIDXNZAXMDK-UHFFFAOYSA-N

(R)-(-)-2-Pentanol Safety Profile

Hazard Codes of (R)-(-)-1-Phenyl-1,2-ethanediol (CAS NO.31087-44-2): HarmfulXn
Risk Statements: 10-20
R10:Flammable. 
R20:Harmful by inhalation.
Safety Statements: 24/25
S24/25:Avoid contact with skin and eyes.

(R)-(-)-2-Pentanol Specification

 (R)-(-)-2-Pentanol ,its cas register number is 31087-44-2. It also can be called Methyl propyl carbinol ; 2-Hydroxypentane ; sec-Pentyl alcohol and sec-Amyl alcohol .

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