4-Chlorobenzhydrylchloride supplier

Name
4-Chlorobenzhydrylchloride
EINECS 205-158-6
CAS No. 134-83-8
Article Data23
CAS DataBase
Density 1.23 g/cm³
Solubility immiscible with water
Melting Point
Formula C₁₃H₁₀Cl₂
Boiling Point 352.7 °C at 760 mmHg
Molecular Weight 237.128
Flash Point 146.9 °C
Transport Information UN 3265 8/PG 2
Appearance colorless or Off-yellow liquid
Safety 26-27-36/37/39-45
Risk Codes 34-36/37-36
Molecular Structure
Hazard Symbols C
Synonyms Methane,chloro(p-chlorophenyl)phenyl- (6CI,7CI,8CI);4-Chlorobenzhydryl chloride;Chloro(p-chlorophenyl)phenylmethane;NSC 49126;p-Chlorobenzhydryl chloride;Chloro(4-chlorophenyl)phenylmethane;
PSA 0.00000
LogP 4.66820

Synthetic route

: 119-56-2
(4-chlorophenyl)phenylmethanol

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

Conditions

Conditions	Yield
With hydrogenchloride In ethanol Heating;	95%
With hydrogenchloride; diethyl ether
With hydrogenchloride; benzene

: 134-85-0
4-chlorobenzophenone

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 90 percent / sodium borohydride 2: 95 percent / hydrochloric acid / ethanol / Heating View Scheme
Multi-step reaction with 2 steps 1: NaBH4 / tetrahydrofuran 2: HCl, CaCl2 / benzene View Scheme
Multi-step reaction with 2 steps 1: NaBH4 / propan-2-ol 2: HCl, Drierite / CH2Cl2 View Scheme

: 831-81-2
4-chlorophenyl(phenyl)methane

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

Conditions

Conditions	Yield
With N-chloro-succinimide; 9-(2-mesityl)-10-methylacridinium perchlorate In dichloromethane at 20℃; for 1h; Sealed tube; Inert atmosphere; Irradiation;

: 104-88-1
4-chlorobenzaldehyde

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrahydrofuran / 1 h / 20 °C 2: SOCl2 / CH2Cl2 / 1 h / 0 °C View Scheme

: phenylmagnesium bromide

isopropyl magnesium halide: isopropyl magnesium halide

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrahydrofuran / 1 h / 20 °C 2: SOCl2 / CH2Cl2 / 1 h / 0 °C View Scheme

: 7647-01-0
hydrogenchloride

: 119-56-2
(4-chlorophenyl)phenylmethanol

: 71-43-2
benzene

A: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

B: 7732-18-5
water

Conditions

Conditions	Yield
at 60℃; Equilibrium constant;

...Expand

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 134-85-0
4-chlorobenzophenone

Conditions

Conditions	Yield
With N-Bromosuccinimide; water In chloroform for 3h; Time; Reflux;	97%

: 120-43-4
4-ethoxycarbonylpiperazine

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 80476-89-7
ethyl {4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl}carboxylate

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 24h;	96%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: (R)-5-Oxo-1-trimethylsilanyl-pyrrolidine-2-carboxylic acid methyl ester

A: 75-77-4
chloro-trimethyl-silane

B: (R)-1-[(4-Chloro-phenyl)-phenyl-methyl]-5-oxo-pyrrolidine-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid at 130℃; for 1.5h;	A n/a B 91%

...Expand

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 603-35-0
triphenylphosphine

: 25361-60-8
<(4-chlorophenyl)phenylmethyl>triphenylphosphonium chloride

Conditions

Conditions	Yield
at 160℃; for 6h;	88%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 795281-42-4
bis[p-chlorophenyl(phenyl)methyl] diselenide

Conditions

Conditions	Yield
With sodium hydroxide; selenium; hydrazine hydrate In N,N-dimethyl-formamide at 20℃; for 6h;	86%

: 201230-82-2
carbon monoxide

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 21771-88-0
α-(4-chlorophenyl)phenylacetic acid

Conditions

Conditions	Yield
With sodium hydroxide; sodium tetracarbonyl cobaltate In ethanol at 16℃;	62.8%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 150583-22-5
RTI 100

: 2β-[(4-chlorophenyl)phenylmethoxymethyl]-3β-(4-fluorophenyl)tropane

Conditions

Conditions	Yield
at 180℃; for 1h;	60%

: 110-85-0
piperazine

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 303-26-4
N-(4-chlorobenzhydryl)piperazine

Conditions

Conditions	Yield
With K2CO3; Ki In dichloromethane; butanone	57%
With Ki; potassium carbonate In dichloromethane; butanone	57%
With Ki; potassium carbonate In dichloromethane; butanone	57%

: 51-17-2
benzoimidazole

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 1326231-74-6
1-((4-chlorophenyl)(phenyl)methyl)-1H-benzo[d]imidazole

Conditions

Conditions	Yield
With tetraethylammonium iodide; potassium carbonate; sodium hydroxide In acetonitrile for 36h; Reflux;	56.6%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 307519-45-5
3β-(4-methylphenyl)-2β-hydroxymethyltropane

: 2β-[(4-chlorophenyl)phenylmethoxymethyl]-3β-tolyltropane

Conditions

Conditions	Yield
at 180℃; for 1h;	50%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 173830-08-5
2α-hydroxymethyl-3β-(4-chlorophenyl)tropane

: 2α-[(4-chlorophenyl)phenylmethoxymethyl]-3β-(4-chlorophenyl)tropane

Conditions

Conditions	Yield
at 180℃; for 1h;	48%

: 95-14-7
1,2,3-Benzotriazole

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 182057-17-6
1-[(4-chlorophenyl)(phenyl)methyl]-1H-1,2,3-benzotriazole

Conditions

Conditions	Yield
With tetraethylammonium iodide; potassium carbonate; sodium hydroxide In acetonitrile for 48h; Reflux;	48%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 409360-24-3
2α-hydroxymethyl-3β-p-tolyltropane

: 2α-[(4-chlorophenyl)phenylmethoxymethyl]-3β-tolyltropane

Conditions

Conditions	Yield
at 180℃; for 1h;	45%

: (+/-)-6β-methoxymethoxy-8-methyl-8-azabicyclo[3.2.1]octan-3α-ol

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: (+/-)-3α-[(4-chlorophenyl)phenylmethoxy]-6β-methoxymethoxy-8-methyl-8-azabicyclo[3.2.1]octan-3α-ol

Conditions

Conditions	Yield
With tributyl-amine In N,N-dimethyl-formamide at 160℃; for 8h;	44%

: 505-66-8
1,4-Diazacycloheptane

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 24342-60-7
1-<(4-chlorophenyl)phenylmethyl>homopiperazine

Conditions

Conditions	Yield
In chloroform for 72h; Reflux;	43%

: 1666-13-3
diphenyl diselenide

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: ((4-chlorophenyl)(phenyl)methyl) phenyl selenide

Conditions

Conditions	Yield
With sodium tetrahydroborate In tetrahydrofuran; ethanol at 20℃; for 36h; Inert atmosphere;	42%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 793684-90-9
1,4-bis(diphenylphosphino)-2,5-dibromo-3,6-difluorobenzene

: 1,2,4,5-Tetrakis-diphenylphosphanyl-3,6-difluoro-benzene

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane at -80℃; for 2h;	40%

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 1-[(4-chlorophenyl)phenylmethyl]piperazine-2,2,3,3,5,5,6,6-d8

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 85℃; Sealed tube;	32.1%

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 135-97-7
pseudotropine

: 3β-<(4'-chlorophenyl)phenylmethoxy>tropane hydrochloride

Conditions

Conditions	Yield
at 160℃;	31%

: 288-32-4
1H-imidazole

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 102993-83-9
1-[(4-chlorophenyl)(phenyl)methyl]-1H-imidazole

Conditions

Conditions	Yield
In acetonitrile for 2h; Heating;	13%
In 1,4-dioxane Reflux;
With tetraethylammonium iodide; potassium carbonate; sodium hydroxide In acetonitrile for 24h; Reflux;

4-Chlorobenzhydrylchloride Chemical Properties

Product Name: 4-Chlorobenzhydrylchloride (CAS NO.134-83-8)

Molecular Formula: C₁₃H₁₀Cl₂
Molecular Weight: 237.13g/mol
Mol File: 134-83-8.mol
EINECS: 205-158-6
Appearance: clear light yellow liquid
Boiling point: 319.6 °C at 760 mmHg
Flash Point: 139.8 °C
Density: 1.23 g/cm³
Refractive index: n20/D 1.603(lit.)
Water Solubility: IMMISCIBLE
Sensitive: Moisture Sensitive
Index of Refraction: 1.593
Molar Refractivity: 65.35 cm³
Molar Volume: 192.7 cm³
Surface Tension: 41.7 dyne/cm
Enthalpy of Vaporization: 53.89 kJ/mol
Vapour Pressure: 0.000626 mmHg at 25°C
XLogP3-AA: 5.1
H-Bond Donor: 0
H-Bond Acceptor: 0
Structure Descriptors of 4-Chlorobenzhydrylchloride (CAS NO.134-83-8):
IUPAC Name: 1-chloro-4-[chloro(phenyl)methyl]benzene
Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=C(C=C2)Cl)Cl
InChI: InChI=1S/C13H10Cl2/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13H
InChIKey: ALKWTKGPKKAZMN-UHFFFAOYSA-N

4-Chlorobenzhydrylchloride Safety Profile

Safety Information of 4-Chlorobenzhydrylchloride (CAS NO.134-83-8):
Hazard Codes: C Corrosive
Risk Statements: 34-36/37-36
R34:Causes burns.
R36/37:Irritating to eyes and respiratory system.
R36:Irritating to eyes.
Safety Statements: 26-27-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27:Take off immediately all contaminated clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
HazardClass: 8
PackingGroup: II
HS Code: 29036990

4-Chlorobenzhydrylchloride Specification

4-Chlorobenzhydrylchloride , its CAS NO. is 134-83-8, the synonyms are Chloro(p-chlorophenyl)phenylmethane ; Benzene, 1-chloro-4-(chlorophenylmethyl)- ; Methane, chloro(p-chlorophenyl)phenyl- (8CI) ; alpha,4-Dichloro-alpha-phenyltoluene .

Product Name

4-Chlorobenzhydrylchloride

Synthetic route

4-Chlorobenzhydrylchloride Chemical Properties

4-Chlorobenzhydrylchloride Safety Profile

4-Chlorobenzhydrylchloride Specification

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