Product Name

  • Name

    Vinyl chloride

  • EINECS 200-831-0
  • CAS No. 75-01-4
  • Article Data372
  • CAS DataBase
  • Density 0.918 g/cm3
  • Solubility acetone/carbon disulfide, MEK, THF: soluble
  • Melting Point -153.8 °C(lit.)
  • Formula C2H3Cl
  • Boiling Point -13.4 °C(lit.)
  • Molecular Weight 62.4988
  • Flash Point -78 °F
  • Transport Information
  • Appearance colourless gas
  • Safety 53-45-36/37
  • Risk Codes 45-12-39/23/24/25-23/24/25-11
  • Molecular Structure Molecular Structure of 75-01-4 (Vinyl chloride)
  • Hazard Symbols HighlyF+; ToxicT
  • Synonyms Vinyl chloride;Vinylchloride monomer;Ethylene,chloro- (8CI);1-Chloroethene;1-Chloroethylene;Chloroethene;Chloroethylene;F 1140;Monochloroethylene;VCM;Vinyl C monomer;
  • PSA 0.00000
  • LogP 1.36870

Synthetic route

acetylene
74-86-2

acetylene

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With hydrogenchloride; oxygen at 199.84℃; under 750.075 Torr; for 12h; Reagent/catalyst; Flow reactor; Inert atmosphere;100%
With hydrogenchloride at 180℃; Reagent/catalyst;99.9%
With hydrogenchloride In water at 250℃; under 825.083 - 900.09 Torr; Temperature; Reagent/catalyst;68%
1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

A

hydrogenchloride
7647-01-0

hydrogenchloride

B

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
at 450 - 550℃; under 10501.1 - 26252.6 Torr; for 0.00416667 - 0.00833333h;A n/a
B 99.52%
at 362 - 485℃; eine nahezu homogene Reaktion erster Ordnung, die wahrscheinlich von Chloratomen und 1.2-Dichlor-aethyl-Radikalen unterhalten wird.Thermolysis;
at 600℃; Conversion of starting material;
at 615℃; Rate constant;
at 650℃; Rate constant;
1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With triethylbenzylammonium ethanolate at -20 - 20℃;99%
75%
With polyacrylonitrile-based active carbon fiber at 350℃; under 760 Torr; for 2h; other catalyst, var. reaction time;57%
-butyl vinyl ether
111-34-2

-butyl vinyl ether

Phenyltrichlorosilane
98-13-5

Phenyltrichlorosilane

A

chloroethylene
75-01-4

chloroethylene

B

dichloro(butoxy)phenylsilane
17887-35-3

dichloro(butoxy)phenylsilane

Conditions
ConditionsYield
at 20℃; for 24h;A n/a
B 96%
methylchlorodiazirine
4222-21-3

methylchlorodiazirine

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
In n-heptane Quantum yield; Irradiation;90%
β-chlorovinyl(methyl)dichlorosilane
13852-29-4

β-chlorovinyl(methyl)dichlorosilane

A

Methyltrichlorosilane
75-79-6

Methyltrichlorosilane

B

1,1-dichloroethane
75-34-3

1,1-dichloroethane

C

chloroethylene
75-01-4

chloroethylene

D

dichloro-(2,2-dichloro-ethyl)-methyl-silane

dichloro-(2,2-dichloro-ethyl)-methyl-silane

Conditions
ConditionsYield
With hydrogenchloride; iron(III) chloride at 25 - 31℃; for 4h; Product distribution; Further Variations:; Temperatures; reaction time, reagent concentration; Addition; elimination;A n/a
B n/a
C n/a
D 89%
1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

A

ethene
74-85-1

ethene

B

chloroethane
75-00-3

chloroethane

C

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With hydrogen; Ni on pumice at 350℃; Product distribution; other temperature;A 83.7%
B 0.6%
C 0.7%
Trichloroethylene
79-01-6

Trichloroethylene

A

cis-1,2-Dichloroethylene
156-59-2

cis-1,2-Dichloroethylene

B

chloroethylene
75-01-4

chloroethylene

C

acetylene
74-86-2

acetylene

Conditions
ConditionsYield
With iron sulfide In water for 2922h; pH=8.3; Kinetics; Product distribution; Dehydrochlorination;A 6%
B 1%
C 65%
-butyl vinyl ether
111-34-2

-butyl vinyl ether

(chloromethyl)trichlorosilane
1558-25-4

(chloromethyl)trichlorosilane

A

chloroethylene
75-01-4

chloroethylene

B

dichloro(chloromethyl)butoxysilane

dichloro(chloromethyl)butoxysilane

Conditions
ConditionsYield
at 20℃; for 24h;A n/a
B 57%
Methyltrichlorosilane
75-79-6

Methyltrichlorosilane

-butyl vinyl ether
111-34-2

-butyl vinyl ether

A

chloroethylene
75-01-4

chloroethylene

B

dichloro(butoxy)methylsilane
1825-78-1

dichloro(butoxy)methylsilane

Conditions
ConditionsYield
at 20℃; for 24h;A n/a
B 45%
(tris(3,5-dimethylpyrazolyl)borate)Rh(PMe3)(CH3)H

(tris(3,5-dimethylpyrazolyl)borate)Rh(PMe3)(CH3)H

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

A

ethene
74-85-1

ethene

B

chloroethylene
75-01-4

chloroethylene

C

(η(3)-tris(3,5-dimethylpyrazolyl)borato)Rh(PMe3)(Cl)2

(η(3)-tris(3,5-dimethylpyrazolyl)borato)Rh(PMe3)(Cl)2

D

[(HB(N2C3H(CH3)2)3)RhH(P(CH3)3)Cl]

[(HB(N2C3H(CH3)2)3)RhH(P(CH3)3)Cl]

Tp’RhCl(PMe3)(η1-CH=CH2)

Tp’RhCl(PMe3)(η1-CH=CH2)

Conditions
ConditionsYield
at 22℃; for 72h; Sealed tube; Inert atmosphere;A Ca. 10 %Spectr.
B Ca. 15 %Spectr.
C 41%
D 44%
E 15%
methylene chloride
74-87-3

methylene chloride

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With oxygen at 600℃; Reagent/catalyst;42%
-butyl vinyl ether
111-34-2

-butyl vinyl ether

A

chloroethylene
75-01-4

chloroethylene

B

n-butoxytrichlorosilane
1825-85-0

n-butoxytrichlorosilane

Conditions
ConditionsYield
With tetrachlorosilane at 20℃; for 24h;A n/a
B 37%
-butyl vinyl ether
111-34-2

-butyl vinyl ether

dichloromethylphenylsilane
149-74-6

dichloromethylphenylsilane

A

chloroethylene
75-01-4

chloroethylene

B

chloro(butoxy)(methyl)phenylsilane
18001-27-9

chloro(butoxy)(methyl)phenylsilane

Conditions
ConditionsYield
at 20℃; for 24h;A n/a
B 32%
dichloromethane
75-09-2

dichloromethane

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With hydrogen at 500℃; under 1520.1 Torr; Reagent/catalyst; Temperature; Pressure;23.2%
1,1-dichloroethane
75-34-3

1,1-dichloroethane

ethene
74-85-1

ethene

A

chloroethane
75-00-3

chloroethane

B

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With calcium sulfate at 260℃; under 14710.2 Torr;
1,1-dichloroethane
75-34-3

1,1-dichloroethane

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With sodium ethanolate
With pumice stone
With Y-type zeolite In chloroform at 125℃; under 760.051 Torr; Temperature;
With aluminum oxide at 300℃;
cis-dichloro(2-chlorovinyl) arsine
34461-56-8

cis-dichloro(2-chlorovinyl) arsine

1-methyl-4-nitrosobenzene
623-11-0

1-methyl-4-nitrosobenzene

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
at 40℃;
ethane
74-84-0

ethane

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With aluminum oxide; chlorine at 400℃;
at 380℃; bei der thermischen Chlorieren;
bei der photochemischen Chlorierung;
With chlorine at 500℃;
With hydrogenchloride In neat (no solvent, gas phase) at 400℃; Kinetics; Catalytic behavior; Temperature; Reagent/catalyst;
ethene
74-85-1

ethene

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With chlorine at 400℃;
With chlorine anschl. HCl-Abspaltung ueber Aktivkohle bei 400grad-450grad;
With chlorine
1-chloro-1-fluoroethane
1615-75-4

1-chloro-1-fluoroethane

A

1-fluoroethylene
75-02-5

1-fluoroethylene

B

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
at 600℃;
1,1,2-trichloroethane
79-00-5

1,1,2-trichloroethane

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With sodium amalgam; nickel(I)octaethylisobacteriochlorin In N,N-dimethyl-formamide at 23℃; Rate constant;
With water; iron at 100 - 120℃; unter Druck;
With water; zinc at 50 - 60℃;
2-chloro-1-acetoxyethane
542-58-5

2-chloro-1-acetoxyethane

A

chloroethylene
75-01-4

chloroethylene

B

acetic acid
64-19-7

acetic acid

Conditions
ConditionsYield
Erhitzen;
2-chloroethyl benzenesulfonate
16670-48-7

2-chloroethyl benzenesulfonate

A

chloroethylene
75-01-4

chloroethylene

B

acetaldehyde
75-07-0

acetaldehyde

C

benzenesulfonic acid
98-11-3

benzenesulfonic acid

Conditions
ConditionsYield
at 285 - 290℃;
1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

acetylene
74-86-2

acetylene

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With mercury(I) chloride; potassium chloride at 375℃;
With mercury dichloride; barium(II) chloride at 350 - 450℃;
ethylene dibromide
106-93-4

ethylene dibromide

A

2-fluoroethyl bromide
762-49-2

2-fluoroethyl bromide

B

chloroethylene
75-01-4

chloroethylene

Conditions
ConditionsYield
With potassium fluoride; ethylene glycol at 150℃;
With potassium fluoride at 200℃;
3-oxa-1,5-dichloropentane
111-44-4

3-oxa-1,5-dichloropentane

A

chloroethylene
75-01-4

chloroethylene

B

2-chloroetyl vinyl ether
110-75-8

2-chloroetyl vinyl ether

Conditions
ConditionsYield
at 450℃;
chlorobenzene
108-90-7

chlorobenzene

chloroethylene
75-01-4

chloroethylene

chloroethylene
75-01-4

chloroethylene

bis-trifluoromethyl-aminooxyl
2154-71-4

bis-trifluoromethyl-aminooxyl

1,2-bischloroethane
67329-57-1

1,2-bischloroethane

Conditions
ConditionsYield
for 0.833333h; Ambient temperature;99%
chloroethylene
75-01-4

chloroethylene

perfluoro(2,4-dimethyl-3-oxa-2,4-diazapentane)
6141-72-6

perfluoro(2,4-dimethyl-3-oxa-2,4-diazapentane)

O-[2-(Bis-trifluoromethyl-amino)-1-chloro-ethyl]-N,N-bis-trifluoromethyl-hydroxylamine

O-[2-(Bis-trifluoromethyl-amino)-1-chloro-ethyl]-N,N-bis-trifluoromethyl-hydroxylamine

Conditions
ConditionsYield
for 120h; Ambient temperature; in vacuo;98%
chloroethylene
75-01-4

chloroethylene

1-chloro-1,3-bis(2,4,6-trichlorophenyl)triazene
187464-05-7

1-chloro-1,3-bis(2,4,6-trichlorophenyl)triazene

1,3-bis(2,4,6-trichlorophenyl)-1,2,3-triazolium hexachloroantimonate

1,3-bis(2,4,6-trichlorophenyl)-1,2,3-triazolium hexachloroantimonate

Conditions
ConditionsYield
With antimonypentachloride In dichloromethane at -60 - 23℃; for 1.75h;98%
3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde
115104-40-0

3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde

chloroethylene
75-01-4

chloroethylene

1‐[3‐(2‐(7-chloro‐2‐quinolinyl)vinyl)phenyl]‐2-propen-1-ol

1‐[3‐(2‐(7-chloro‐2‐quinolinyl)vinyl)phenyl]‐2-propen-1-ol

Conditions
ConditionsYield
With ammonium acetate In toluene at -2 - 5℃; Reagent/catalyst; Inert atmosphere;97.2%
methanol
67-56-1

methanol

chloroethylene
75-01-4

chloroethylene

chloroacetaldehyde dimethyl acetal
97-97-2

chloroacetaldehyde dimethyl acetal

Conditions
ConditionsYield
With sodium methylate; chlorine at 25 - 27℃; for 5.5h; pH=3 - 7; Temperature; Large scale;97.2%
chloroethylene
75-01-4

chloroethylene

1,2-dibromo-1-chloroethane
598-20-9

1,2-dibromo-1-chloroethane

Conditions
ConditionsYield
With bromine at 20℃; for 17h; Cooling;97%
With bromine
With bromine In tetrachloromethane
With bromine; dinitrogen tetraoxide In chloroform
With bromine; Nitrogen dioxide at 325℃;
tetrachloromethane
56-23-5

tetrachloromethane

chloroethylene
75-01-4

chloroethylene

1,1,1,3,3-pentachloropropane
23153-23-3

1,1,1,3,3-pentachloropropane

Conditions
ConditionsYield
With iron; orthoformic acid triethyl ester at 130℃; under 2250.23 Torr; for 0.5h; Temperature; Pressure; Reagent/catalyst;96.6%
With iron(III) chloride; phosphoric acid tributyl ester under 1125.11 Torr; for 100h; Flow reactor; Large scale;95.6%
Stage #1: tetrachloromethane With N,N,N,N,N,N-hexamethylphosphoric triamide; chloroform; iron at 140℃; for 0.5h; Autoclave; Inert atmosphere;
Stage #2: chloroethylene at 140℃; for 3h; Reagent/catalyst; Autoclave; Inert atmosphere;
93.1%
benzophenone
119-61-9

benzophenone

chloroethylene
75-01-4

chloroethylene

1,1-diphenylprop-2-en-1-ol
3923-51-1

1,1-diphenylprop-2-en-1-ol

Conditions
ConditionsYield
Stage #1: chloroethylene; zinc(II) chloride In tetrahydrofuran at 20℃; for 1h;
Stage #2: benzophenone In tetrahydrofuran at 0℃; for 2h;
96%
chloroethylene
75-01-4

chloroethylene

[Li(Et2O)2.8][B(C6F5)4]

[Li(Et2O)2.8][B(C6F5)4]

chloro(4,4'-di-tert-butyl-2,2'-bipyridine)methylpalladium(II)
524936-75-2

chloro(4,4'-di-tert-butyl-2,2'-bipyridine)methylpalladium(II)

carbon monoxide
201230-82-2

carbon monoxide

[(4,4'-di-tert-butyl-2,2'-bipyridine)Pd(CHClCH2COMe)][B(C6F5)4]
524936-99-0

[(4,4'-di-tert-butyl-2,2'-bipyridine)Pd(CHClCH2COMe)][B(C6F5)4]

Conditions
ConditionsYield
In dichloromethane-d2 byproducts: LiCl, Et2O; stirring of ((t-Bu)2bipy)PdMeCl, (Li(Et2O)2.8)B(C6F5)4 (1 eqiuv.) and CH2Cl2 in Schlenk flask at -78°C for 10 min, exposure to CO (1 atm)at -78°C for 30 min, freezing to -196°C, evacuating, addn . of CH2CHCl, stirring at 23°C; filtration, drying of filtrate under vac., elem. anal.;96%
chloroethylene
75-01-4

chloroethylene

1,8-diazabicyclo[5.4.0]undec-7-ene
6674-22-2

1,8-diazabicyclo[5.4.0]undec-7-ene

6-vinyl DBU
1268387-98-9

6-vinyl DBU

Conditions
ConditionsYield
Stage #1: 1,8-diazabicyclo[5.4.0]undec-7-ene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: chloroethylene In tetrahydrofuran; hexane at -78 - 20℃;
96%
chloroethylene
75-01-4

chloroethylene

4-(Methylthio)benzaldehyde
3446-89-7

4-(Methylthio)benzaldehyde

1-[4-(methylsulfanyl)phenyl]-2-propen-1-ol
701935-64-0

1-[4-(methylsulfanyl)phenyl]-2-propen-1-ol

Conditions
ConditionsYield
Stage #1: chloroethylene With magnesium In tetrahydrofuran at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: 4-(Methylthio)benzaldehyde In tetrahydrofuran at 0 - 20℃; Grignard reaction;
Stage #3: With water; ammonium chloride In tetrahydrofuran Grignard reaction;
96%
chloroethylene
75-01-4

chloroethylene

9H-carbazole
86-74-8

9H-carbazole

9-vinyl-9H-carbazole
1484-13-5

9-vinyl-9H-carbazole

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); sodium hydroxide; tri tert-butylphosphoniumtetrafluoroborate In toluene at 100℃; for 10h; Reagent/catalyst; Inert atmosphere;96%
tertiary butyl chloride
507-20-0

tertiary butyl chloride

chloroethylene
75-01-4

chloroethylene

1,1-dichloro-3,3-dimethylbutane
6130-96-7

1,1-dichloro-3,3-dimethylbutane

Conditions
ConditionsYield
With aluminium trichloride In dichloromethane at -40 - -10℃; for 0.5h;95%
With iron(III) chloride unter Stickstoffdruck;
With aluminium trichloride at -25℃;
With iron(III) chloride
With aluminium trichloride
chloroethylene
75-01-4

chloroethylene

rac-(EBI)Zr(Me)(μ-Me)B(C6F5)3

rac-(EBI)Zr(Me)(μ-Me)B(C6F5)3

oligopropylene, atactic, Mn = 500

oligopropylene, atactic, Mn = 500

Conditions
ConditionsYield
In dichloromethane-d2 at 25℃; for 24h; Polymerization; dechlorination; methylation;95%
chloroethylene
75-01-4

chloroethylene

carbon monoxide
201230-82-2

carbon monoxide

dimethyl amine
124-40-3

dimethyl amine

3-(dimthylamino)-N,Ndimethylpropanamide hydrochloride
110570-37-1

3-(dimthylamino)-N,Ndimethylpropanamide hydrochloride

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) at 100℃; Product distribution; Mechanism; other substituted vinyl chlorides, other amines and NH3, var. temp.;94%
chloroethylene
75-01-4

chloroethylene

bis-(3,5-dimethylphenyl)chlorophosphine
74289-57-9

bis-(3,5-dimethylphenyl)chlorophosphine

vinyl bis(3,5-dimethylphenyl)phosphine

vinyl bis(3,5-dimethylphenyl)phosphine

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; for 10h; Inert atmosphere;94%
chloroethylene
75-01-4

chloroethylene

N-phenylbenzohydrazonoyl chloride
15424-14-3

N-phenylbenzohydrazonoyl chloride

1,3-diphenyl-1H-pyrazole
4492-01-7

1,3-diphenyl-1H-pyrazole

Conditions
ConditionsYield
With triethylamine; hydroquinone In benzene for 48h; Ambient temperature;93%
chloroethylene
75-01-4

chloroethylene

1,1,2,2,3,3-Hexafluoro-cyclopropane
931-91-9

1,1,2,2,3,3-Hexafluoro-cyclopropane

A

polytetrafluoroethylene
116-14-3

polytetrafluoroethylene

B

Octafluorocyclobutane
115-25-3

Octafluorocyclobutane

C

1,1-difluoro-2-chlorocyclopropane
54944-21-7

1,1-difluoro-2-chlorocyclopropane

Conditions
ConditionsYield
at 294℃; for 1h; sealed tube in vacuo;A 91%
B 19%
C 55%
chloroethylene
75-01-4

chloroethylene

[Li(Et2O)2.8][B(C6F5)4]

[Li(Et2O)2.8][B(C6F5)4]

[(4,4'-dimethyl-2,2'-bipyridine)Pd(Me)Cl]
524936-74-1

[(4,4'-dimethyl-2,2'-bipyridine)Pd(Me)Cl]

carbon monoxide
201230-82-2

carbon monoxide

[(4,4'-dimethyl-2,2'-bipyridine)Pd(CHClCH2COMe)][B(C6F5)4]
524936-97-8

[(4,4'-dimethyl-2,2'-bipyridine)Pd(CHClCH2COMe)][B(C6F5)4]

Conditions
ConditionsYield
In dichloromethane-d2 byproducts: LiCl, Et2O; stirring of (Me2bipy)PdMeCl, (Li(Et2O)2.8)(B(C6F5)4) (1 equiv.) and CH2Cl2 in Schlenk flask at -78°C for 10 min, exposure to CO (1 atm) at -78°C for 30 min, freezing to -196°C, evacuating, addn. of CH2CHCl, stirring at 23°C; filtration, drying of filtrate under vac., elem. anal.;91%
chloroethylene
75-01-4

chloroethylene

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane
16801-24-4

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane - vinyl chloride copolymer, vinyl chloride 74.24 mol percent; monomer(s): 1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane; vinyl chloride

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane - vinyl chloride copolymer, vinyl chloride 74.24 mol percent; monomer(s): 1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane; vinyl chloride

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile) In dimethyl sulfoxide at 70℃;88.9%
chloroethylene
75-01-4

chloroethylene

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane
16801-24-4

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane - vinyl chloride copolymer, vinyl chloride 77.78 mol percent; monomer(s): 1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane; vinyl chloride

1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane - vinyl chloride copolymer, vinyl chloride 77.78 mol percent; monomer(s): 1-{2-[2-(2-vinyloxyethoxy)ethoxy]ethoxy}-2,3-epoxypropane; vinyl chloride

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile) In acetone at 70℃;88.6%
[PdCl(CH3)(bis(diphenylphosphino)propane)]
139168-06-2

[PdCl(CH3)(bis(diphenylphosphino)propane)]

chloroethylene
75-01-4

chloroethylene

[Li(Et2O)2.8][B(C6F5)4]

[Li(Et2O)2.8][B(C6F5)4]

carbon monoxide
201230-82-2

carbon monoxide

[(1,3-bis(diphenylphosphino)propane)Pd(CHClCH2COMe)][B(C6F5)4]
524937-01-7

[(1,3-bis(diphenylphosphino)propane)Pd(CHClCH2COMe)][B(C6F5)4]

Conditions
ConditionsYield
In dichloromethane-d2 byproducts: LiCl, Et2O; stirring of (dppp)PdMeCl, (Li(Et2O)2.8)B(C6F5)4 (1 eqiuv.) and CH2Cl2 inSchlenk flask at -78°C for 10 min, exposure to CO (1 atm) at -78 °C for 30 min, freezing to -196°C, evacuating, addn. of CH2CHCl, stirring at 23°C; filtration, drying of filtrate under vac., elem. anal.;88%

Vinyl chloride History

In 1835, Vinyl chloride (CAS NO.75-01-4) was first produced by Justus von Liebig and his student Henri Victor Regnault. They obtained it by treating ethylene dichloride with a solution of potassium hydroxide in ethanol.
In 1912, Frans, a German chemist working for Griesheim-Elektron, patented a means to produce vinyl chloride from acetylene and hydrogen chloride using mercuric chloride as a catalyst. Whereas this method was widely used during the 1930s and 1940s, it has since been superseded by more economical processes, at least in the West.

Vinyl chloride Consensus Reports

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 373.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 19 ,1979,p. 377.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1974,p. 291.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1974,p. 291.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 19 ,1979,p. 377.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Vinyl chloride Standards and Recommendations

OSHA PEL: Cancer Suspect Agent
ACGIH TLV: TWA 1 ppm; Confirmed Human Carcinogen
DFG MAK: DFG TRK: Confirmed Human Carcinogen
NIOSH REL: (Vinyl Chloride) Lowest Detectable Level
DOT Classification:  2.1; Label: Flammable Gas

Vinyl chloride Analytical Methods

For occupational chemical analysis use OSHA: #04 or NIOSH: Vinyl Chloride, 1007.

Vinyl chloride Specification

The Vinyl chloride, with the CAS registry number 75-01-4 and EINECS registry number 200-831-0, has the systematic name of chloroethene. And the molecular formula of this chemical is C2H3Cl. It is a kind of colourless gas with a sickly sweet odor, and also called VCM which is shourt for vinyl chloride monomer.

The physical properties of Vinyl chloride are as following: (1)ACD/LogP: 1.69; (2)ACD/LogD (pH 5.5): 1.69; (3)ACD/LogD (pH 7.4): 1.69; (4)ACD/BCF (pH 5.5): 11.33; (5)ACD/BCF (pH 7.4): 11.33; (6)ACD/KOC (pH 5.5): 197.82; (7)ACD/KOC (pH 7.4): 197.82; (8)Index of Refraction: 1.384; (9)Molar Refractivity: 15.889 cm3; (10)Molar Volume: 68.027 cm3; (11)Polarizability: 6.299 10-24cm3; (12)Surface Tension: 17.5160007476807 dyne/cm; (13)Density: 0.919 g/cm3; (14)Flash Point: -55.958 °C; (15)Enthalpy of Vaporization: 23.039 kJ/mol; (16)Boiling Point: -10.545 °C at 760 mmHg; (17)Vapour Pressure: 2579.74291992188 mmHg at 25°C

Preparation of Vinyl chloride: It mainly prepared by two methods, the hydrochlorination of acetylene and the dehydrochlorination of ethylene dichloride (1,2-dichloroethane). And the production of vinyl chloride from 1,2-dichloroethane (EDC) consists of a series of well-defined steps. EDC is prepared by reacting ethylene and chlorine. In the presence of iron(III) chloride as a catalyst, these compounds react exothermically: CH2=CH2 + Cl2→ ClCH2CH2Cl

Uses of Vinyl chloride: It is a chemical intermediate, and often used to produce polyvinyl chloride. And it is used as an inhalational anaesthetic, in a similar vein to ethyl chloride, though its toxicity forced this practice to be abandoned. In addition, it is also used as an aerosol propellant and is the starting material for polyvinyl resins.

You should be cautious while dealing with this chemical. It is a kind of extremely flammable chemical, and has danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed. What's more, it may also cause cancer. Therefore, you had better take the following instructions: Wear suitable protective clothing and gloves; Avoid exposure - obtain special instruction before use; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: Cl\C=C
(2)InChI: InChI=1/C2H3Cl/c1-2-3/h2H,1H2
(3)InChIKey: BZHJMEDXRYGGRV-UHFFFAOYAW

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LCLo inhalation 30pph/30M (300000ppm) BEHAVIORAL: GENERAL ANESTHETIC American Industrial Hygiene Association Journal. Vol. 21, Pg. 394, 1960.
mammal (species unspecified) LCLo inhalation 200ppm/18M (200ppm)   International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
mouse LCLo inhalation 20pph/30M (200000ppm) BEHAVIORAL: GENERAL ANESTHETIC American Industrial Hygiene Association Journal. Vol. 21, Pg. 394, 1960.
rat LC50 inhalation 18pph/15M (180000ppm) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Human Toxicology. Vol. 1, Pg. 239, 1982.
rat LD50 oral 500mg/kg (500mg/kg)   Dow Chemical Company Reports.

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