Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to off-white powder Storage:cool dry place Package:25kg/drum Application:medicine raw material Transportatio
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryDayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product specifica
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inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryTolterodine CAS:124937-51-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
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Cas:124937-51-5
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inquiry1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of hig
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Product name: Tolterodine CAS No.:124937-51-5 Molecule Formula:C22H31NO Molecule Weight:325.48 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING ITEMS
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1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in
Appearance: White or almost white crystalline powder Total impurity: ≤0.2% Assay :≥ 99.0% Appearance:White or almost white crystalline powder or crystals Storage:cool and dry Package:25kg/drum Application:A toadstool alkali receptor antagonis
1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.
(R)-3-(2-(benzyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylpropan-1-amine
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In methanol at 20℃; for 24h; | 100% |
With palladium on activated charcoal; hydrogen In methanol at 20℃; for 24h; | 100% |
With hydrogen; palladium on activated charcoal In methanol at 20℃; under 760 Torr; for 12h; | 97% |
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 1125.11 Torr; for 24h; | 94% |
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With hydrogenchloride In isopropyl alcohol at 50℃; for 22h; | 98% |
(4R)-6-methyl-4-phenylchroman-2-ol
diisopropylamine
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid In methanol at 20℃; for 72h; Inert atmosphere; | 93% |
With palladium 10% on activated carbon; hydrogen In methanol at 50℃; under 2585.81 Torr; for 12h; Autoclave; | 93% |
With hydrogen; palladium on activated charcoal In methanol under 2585.74 Torr; for 12h; Heating; | 91% |
(Z)-2-(3-(diisopropylamino)-1-phenylprop-1-enyl)-4-methylphenol
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With 1,2-bis [(2S,5S)-2,5-diphenylphospholano]ethane 1,5-cyclooctadiene rhodium(I) tetrafluoroborate; hydrogen; lithium tert-butoxide In toluene at 20℃; under 2585.81 Torr; for 2h; Inert atmosphere; optical yield given as %ee; enantioselective reaction; | 89% |
(R)-N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With hydrogen bromide; acetic acid | 87% |
Stage #1: (R)-N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine With boron tribromide In dichloromethane at -78 - 0℃; Stage #2: With methanol In dichloromethane at -78 - 20℃; optical yield given as %ee; |
diisopropyl-(3-phenyl-3-p-toluyloxypropyl)amine
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Stage #1: diisopropyl-(3-phenyl-3-p-toluyloxypropyl)amine With sulfuric acid In water at 20℃; for 3h; Stage #2: With sodium hydroxide In water for 0.5h; pH=9 - 10; Product distribution / selectivity; | 82% |
Stage #1: diisopropyl-(3-phenyl-3-p-toluyloxypropyl)amine at 20℃; for 3h; Stage #2: With sodium hydroxide In water for 0.5h; pH=9 - 10; Product distribution / selectivity; |
C29H37NO3S
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With sodium hydroxide In methanol for 4h; Heating; | 82% |
p-cresol
3-(N,N-diisopropylamino)-1-phenylpropan-1-ol
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Stage #1: p-cresol; 3-(N,N-diisopropylamino)-1-phenylpropan-1-ol With sulfuric acid In water at 40℃; for 3h; Stage #2: With sodium hydroxide In water for 0.5h; pH=9 - 10; Product distribution / selectivity; | 80% |
(4R)-6-methyl-4-phenylchroman-2-ol
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid; diisopropylamine In methanol at 20℃; for 72h; | 48% |
(R)-3-(2-Benzyloxy-5-methyl-phenyl)-N,N-diisopropyl-3-phenyl-propionamide
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal 1) ether, rt, overnight; 2) MeOH, 1 atm, rt, overnight; Yield given. Multistep reaction; | |
Multi-step reaction with 2 steps 1: dimethylsulfide borane complex / tetrahydrofuran / 20 h / Inert atmosphere; Reflux 2: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 20 °C / 1125.11 Torr View Scheme |
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Stage #1: 2-[3-[bis-(1-methylethyl)-amino]-1-phenylpropyl]-4-methylphenol tartrate In water; toluene pH=9.5; Stage #2: With formic acid; tartaric acid In isopropyl alcohol Purification / work up; |
6-methyl-4-phenylchromen-2-one
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: R,R-chiraphos; NaOH; H2 / [Rh(COD)Cl]2 / methanol / 24 h / 50 °C / 9000.9 Torr 1.2: pTsOH / toluene / 4 h / Heating 1.3: DIBALH / toluene / -25 °C 2.1: H2 / Pd/C / methanol / 12 h / 48 °C / 3800.26 Torr View Scheme | |
Multi-step reaction with 2 steps 1: copper diacetate; diethoxymethylsilane; (R,R(Fc))-1-diphenylphosphino-2-(1-dicyclohexylphosphinoethyl)ferrocene / tetrahydrofuran; toluene; tert-butyl alcohol / 3 h / 20 °C / Inert atmosphere 2: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 72 h / 20 °C / Inert atmosphere View Scheme |
(R)-6-methyl-4-phenyl-3,4-dihydrochromen-2-one
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 95 percent / diisobutylaluminum hydride / toluene; hexane / 2.5 h / -25 - -20 °C 2: 91 percent / H2 / Pd/C / methanol / 12 h / 2585.74 Torr / Heating View Scheme | |
Multi-step reaction with 4 steps 1.1: K2CO3 / 1 h / Heating 1.2: NaI / acetone / 36 h / 40 °C 1.3: 87 percent / LiAlH4 / tetrahydrofuran / 4 h / 0 °C 2.1: 83 percent / Et3N; DMAP / CH2Cl2 / 0 - 20 °C 3.1: 81 percent / K2CO3 / acetonitrile / 48 h / 60 °C 4.1: 97 percent / H2 / 10 percent Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme | |
Multi-step reaction with 2 steps 1: diisobutylaluminium hydride / toluene; hexane / -20 - 25 °C / Schlenk technique; Inert atmosphere 2: hydrogen; palladium 10% on activated carbon / methanol / 12 h / 50 °C / 2585.81 Torr / Autoclave View Scheme |
6-methylcoumarin
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 88 percent / Rh(acac)(C2H4)2; (R)-Segphos / dioxane; H2O / 8 h / 60 °C 2: 95 percent / diisobutylaluminum hydride / toluene; hexane / 2.5 h / -25 - -20 °C 3: 91 percent / H2 / Pd/C / methanol / 12 h / 2585.74 Torr / Heating View Scheme |
phenylboronic acid
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 88 percent / Rh(acac)(C2H4)2; (R)-Segphos / dioxane; H2O / 8 h / 60 °C 2: 95 percent / diisobutylaluminum hydride / toluene; hexane / 2.5 h / -25 - -20 °C 3: 91 percent / H2 / Pd/C / methanol / 12 h / 2585.74 Torr / Heating View Scheme |
(R)-3-(2-(benzyloxy)-5-methylphenyl)-3-phenylpropan-1-ol
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 83 percent / Et3N; DMAP / CH2Cl2 / 0 - 20 °C 2: 81 percent / K2CO3 / acetonitrile / 48 h / 60 °C 3: 97 percent / H2 / 10 percent Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme | |
Multi-step reaction with 3 steps 1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / Reflux 2: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 16 h / 20 °C 3: palladium on activated charcoal; hydrogen / methanol / 24 h / 20 °C View Scheme |
(R)-3-[2-(benzyloxy)-5-methylphenyl]-3-phenylpropyl 4-nitrobenzenesulfonate
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 81 percent / K2CO3 / acetonitrile / 48 h / 60 °C 2: 97 percent / H2 / 10 percent Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme |
1-(benzyloxy)-2-bromo-4-methylbenzene
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 1.) Mg, 2.) CuBr*Me2S, Me2S / 1) THF, reflux, 15 min; 2) THF, -50 deg C, 3 min; 3) THF, 10 deg C, 2 h 2: 90 percent / LiOH, H2O2 / tetrahydrofuran; H2O 3: 1.) SOCl2 / 1) benzene, 50 deg C, 50 min; 2) ether, rt, 1.5 h 4: 1.) LiAlH4, 2.) H2 / 2.) Pd/C / 1) ether, rt, overnight; 2) MeOH, 1 atm, rt, overnight View Scheme |
(4R)-3-(3-phenyl-2-(E)-propenoyl)-4-phenyl-2-oxazolidinone
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 1.) Mg, 2.) CuBr*Me2S, Me2S / 1) THF, reflux, 15 min; 2) THF, -50 deg C, 3 min; 3) THF, 10 deg C, 2 h 2: 90 percent / LiOH, H2O2 / tetrahydrofuran; H2O 3: 1.) SOCl2 / 1) benzene, 50 deg C, 50 min; 2) ether, rt, 1.5 h 4: 1.) LiAlH4, 2.) H2 / 2.) Pd/C / 1) ether, rt, overnight; 2) MeOH, 1 atm, rt, overnight View Scheme |
(R)-3-(2-(benzyloxy)-5-methylphenyl)-3-phenylpropanoic acid
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.) SOCl2 / 1) benzene, 50 deg C, 50 min; 2) ether, rt, 1.5 h 2: 1.) LiAlH4, 2.) H2 / 2.) Pd/C / 1) ether, rt, overnight; 2) MeOH, 1 atm, rt, overnight View Scheme | |
Multi-step reaction with 3 steps 1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 24 h / 20 °C / Inert atmosphere 2: dimethylsulfide borane complex / tetrahydrofuran / 20 h / Inert atmosphere; Reflux 3: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 20 °C / 1125.11 Torr View Scheme |
(R)-3-[(R)-3-(2-benzyloxy-5-methylphenyl)-3-phenylpropionyl]-4-phenyloxazolidin-2-one
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 90 percent / LiOH, H2O2 / tetrahydrofuran; H2O 2: 1.) SOCl2 / 1) benzene, 50 deg C, 50 min; 2) ether, rt, 1.5 h 3: 1.) LiAlH4, 2.) H2 / 2.) Pd/C / 1) ether, rt, overnight; 2) MeOH, 1 atm, rt, overnight View Scheme |
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With sodium hydroxide; sodium carbonate In water; toluene |
N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
With boron tribromide In dichloromethane at 0 - 5℃; |
(+/-)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propanamide
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Stage #1: (+/-)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propanamide With lithium aluminium tetrahydride In diethyl ether for 96h; Heating / reflux; Stage #2: With acetic acid In diethyl ether pH=5; Product distribution / selectivity; |
6-methyl-4-phenyl-3,4-dihydrocoumarin
diisopropylamine
A
3-phenyl-3-(2'-hydroxy-5'-methyl)phenylpropanol-1
B
(R)-(+)-tolterodine
C
2-hydroxy-6-methyl-4-phenyldihydrobenzopyran
Conditions | Yield |
---|---|
Stage #1: 6-methyl-4-phenyl-3,4-dihydrocoumarin With diisobutylaluminium hydride In toluene at -25℃; for 5h; Stage #2: With citric acid In water; ethyl acetate; toluene at 20℃; Stage #3: diisopropylamine With hydrogen; 5%-palladium/activated carbon In methanol at 48℃; under 3800.26 Torr; for 12h; |
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: thionyl chloride / tetrahydrofuran / 12 h / 22 °C 2: acetonitrile / 8 h / 60 °C 3: hydrogen bromide / water; acetic acid / 4 h / 112 °C 4: 1,2-bis [(2S,5S)-2,5-diphenylphospholano]ethane 1,5-cyclooctadiene rhodium(I) tetrafluoroborate; hydrogen; lithium tert-butoxide / toluene / 2 h / 20 °C / 2585.81 Torr / Inert atmosphere View Scheme |
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: acetonitrile / 8 h / 60 °C 2: hydrogen bromide / water; acetic acid / 4 h / 112 °C 3: 1,2-bis [(2S,5S)-2,5-diphenylphospholano]ethane 1,5-cyclooctadiene rhodium(I) tetrafluoroborate; hydrogen; lithium tert-butoxide / toluene / 2 h / 20 °C / 2585.81 Torr / Inert atmosphere View Scheme |
(2-methoxy-5-methylphenyl)phenylmethanone
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: tetrahydrofuran / 0 - 22 °C 2: thionyl chloride / tetrahydrofuran / 12 h / 22 °C 3: acetonitrile / 8 h / 60 °C 4: hydrogen bromide / water; acetic acid / 4 h / 112 °C 5: 1,2-bis [(2S,5S)-2,5-diphenylphospholano]ethane 1,5-cyclooctadiene rhodium(I) tetrafluoroborate; hydrogen; lithium tert-butoxide / toluene / 2 h / 20 °C / 2585.81 Torr / Inert atmosphere View Scheme |
2-hydroxy-5-methylbenzaldehyde
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1.1: potassium carbonate 2.1: Inert atmosphere; Schlenk technique 3.1: triethylamine / toluene / 2 h / 150 °C / Inert atmosphere 4.1: sec.-butyllithium / diethyl ether; cyclohexane; hexane / 1 h / -78 °C / Inert atmosphere; Schlenk technique 4.2: 2 h / -78 °C / Inert atmosphere; Schlenk technique 4.3: 16.08 h / -78 - 20 °C / Inert atmosphere; Schlenk technique 5.1: tetrabutyl ammonium fluoride; water / toluene / 1.5 h / 20 °C 6.1: osmium(VIII) oxide; sodium periodate 7.1: sodium tris(acetoxy)borohydride / tetrahydrofuran / 18 h / 20 °C / Inert atmosphere 8.1: hydrogen bromide; acetic acid View Scheme | |
Multi-step reaction with 4 steps 1.1: triphenylphosphine; lithium hydroxide monohydrate; lithium chloride / water / Reflux 2.1: calcium carbonate; palladium diacetate / methanol / 4 h / 60 °C 2.2: 20 °C 3.1: copper diacetate; diethoxymethylsilane; (R,R(Fc))-1-diphenylphosphino-2-(1-dicyclohexylphosphinoethyl)ferrocene / tetrahydrofuran; toluene; tert-butyl alcohol / 3 h / 20 °C / Inert atmosphere 4.1: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 72 h / 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 4 steps 1: triphenylphosphine; lithium hydroxide monohydrate; lithium chloride / water / Reflux 2: calcium carbonate; palladium diacetate / methanol / 60 °C 3: copper diacetate; diethoxymethylsilane; (R,R(Fc))-1-diphenylphosphino-2-(1-dicyclohexylphosphinoethyl)ferrocene / tetrahydrofuran; toluene; tert-butyl alcohol / 3 h / 20 °C / Inert atmosphere 4: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 72 h / 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 9 steps 1.1: toluene / 1.5 h / 80 °C 2.1: potassium carbonate / acetone / 20 °C 2.2: 3 h / Reflux 3.1: oxalyl dichloride; N,N-dimethyl-formamide / tetrahydrofuran / 0.5 h 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C 4.2: 0.75 h / -78 - 0 °C 5.1: palladium diacetate; [2,2]bipyridinyl / methanol; water / 16 h / 80 °C / Schlenk technique; Sealed tube 6.1: lithium borohydride / diethyl ether / 3 h / 0 - 20 °C / Inert atmosphere 7.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / Reflux 8.1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 16 h / 20 °C 9.1: palladium on activated charcoal; hydrogen / methanol / 24 h / 20 °C View Scheme | |
Multi-step reaction with 6 steps 1.1: 18-crown-6 ether; potassium carbonate / acetone / 0.5 h / 20 °C 1.2: 3 h / Reflux 2.1: sodium hydride / mineral oil; tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere 2.2: 2 h / 0 - 20 °C / Inert atmosphere 3.1: potassium hydroxide; C47H55O7P; chlorobis(ethylene)rhodium(I) dimer / water; 1,4-dioxane / 24 h / 20 °C / Inert atmosphere 3.2: 3 h / Reflux 4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 24 h / 20 °C / Inert atmosphere 5.1: dimethylsulfide borane complex / tetrahydrofuran / 20 h / Inert atmosphere; Reflux 6.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 20 °C / 1125.11 Torr View Scheme |
isobutyryl chloride
(R)-(+)-tolterodine
2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-methylphenyl 2-methylpropanoate
Conditions | Yield |
---|---|
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 1h; Inert atmosphere; | 96% |
With sodium hydroxide In tetrahydrofuran; water at 20℃; Inert atmosphere; | 96% |
Stage #1: isobutyryl chloride; (R)-(+)-tolterodine In dichloromethane at -10 - 0℃; Stage #2: With sodium hydrogencarbonate In dichloromethane; water for 0.25h; |
Conditions | Yield |
---|---|
In acetone at 25℃; Inert atmosphere; | 92.3% |
In acetone at 25℃; | 92.3% |
benzenesulfonic acid
(R)-(+)-tolterodine
tolterodine benzene sulfonate
Conditions | Yield |
---|---|
In acetone at 25℃; Inert atmosphere; | 89.9% |
In acetone at 25℃; | 89.9% |
Conditions | Yield |
---|---|
In water at 20℃; for 4h; Temperature; | 87.27% |
(R)-(+)-tolterodine
1-hydroxy-2-naphthoic acid
tolterodine 1-hydroxy-2-naphthate
Conditions | Yield |
---|---|
In acetone at 25℃; Inert atmosphere; | 84.1% |
In acetone at 25℃; | 84.1% |
toluene-4-sulfonic acid
(R)-(+)-tolterodine
tolterodine p-toluene sulfonate
Conditions | Yield |
---|---|
In acetone at 25℃; Inert atmosphere; | 83% |
In acetone at 25℃; | 83% |
(R)-(+)-tolterodine
L-Pyroglutamic acid
tolterodine L-pyroglutamate
Conditions | Yield |
---|---|
In acetone at 25℃; | 82.3% |
In acetone at 25℃; for 1.16667h; | 82.3% |
naphthalene-1,5-disulfonate
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
In acetone at 25℃; for 1.16667h; | 78.4% |
In acetone at 25℃; for 1.16667h; | 78.4% |
Conditions | Yield |
---|---|
In acetone at 25℃; for 1.16667h; | 74.3% |
Conditions | Yield |
---|---|
In acetone at 25℃; for 1.16667h; | 74.3% |
Conditions | Yield |
---|---|
In acetone at 25℃; for 1.16667h; | 73.1% |
In acetone at 25℃; for 1.16667h; | 73.1% |
glycolic Acid
(R)-(+)-tolterodine
(R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-methylphenol 2-hydroxyacetate
Conditions | Yield |
---|---|
In acetone at 25℃; for 1.16667h; | 69.2% |
In acetone at 25℃; for 1.16667h; | 69.2% |
2,5-dihydroxybenzoic acid.
(R)-(+)-tolterodine
tolterodine gentisate
Conditions | Yield |
---|---|
In acetone at 25℃; Inert atmosphere; | 42.5% |
In acetone at 25℃; | 42.5% |
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
(R)-(+)-tolterodine
Conditions | Yield |
---|---|
In acetone at 25℃; | 22.4% |
Conditions | Yield |
---|---|
In ethanol; acetone at 25℃; | 22.4% |
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