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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

1-Hydroxy-2-naphthoic acid, 98+ %

Cas:86-48-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-Hydroxy-2-Naphthoic Acid 97%

Cas:86-48-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 86-48-6 1-Hydroxy-2-naphthoic Acid Manufacturer

Cas:86-48-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality 1-Hydroxy-2-naphthoic acid CAS 86-48-6

Cas:86-48-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

1-Hydroxy-2-naphthoic acid Basic information Product Name: 1-Hydroxy-2-naphthoic acid Synonyms: 1-hydroxy-2-naphthalenecarboxylicaci;1-hydroxy-2-Naphthalenecarboxylicacid;RARECHEM AL BE

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

1-Hydroxy-2-naphthoic acid 86-48-6

Cas:86-48-6

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

HPLC 98% CAS 86-48-6 with competitive price

Cas:86-48-6

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Hydroxy-2-naphthoic acid 86-48-6

Cas:86-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

FOB Price: $52.0 / 65.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

1-Hydroxy-2-naphthoic acid CAS:86-48-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

1-Hydroxy-2-naphthoic acid CAS:86-48-6

Cas:86-48-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:86-48-6

Cas:86-48-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1-hydroxy-2-naphthoic acid 98%

Cas:86-48-6

Min.Order:0

Negotiable

Type:Manufacturers

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

86-48-6 1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

1-HYDROXY-2-NAPHTHOIC ACID

Cas:86-48-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

86-48-6 1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:white to slight red crystaline Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application: Metabolite from phenanthrene degradati

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Siwei Development Group Ltd.

Product name: 1-Hydroxy-2-Naphthoic Acid CAS No.:86-48-6 Molecule Formula:C11H7O3 Molecule Weight:187.17 Purity: 97.0% Package: 25kg/drum Description:White and pale grey powder Manufacture Standards:Enterprise Standard

High Quality 1-Hydroxy-2-Naphthoic Acid

Cas:86-48-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Metric Ton

FOB Price: $5.0 / 8.0

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 1-Hydroxy-2-naphthoic acid CAS: 86-48-6 MF: C11H8O3 MW: 188.18 EINECS: 201-674-0 Mol File: 86-48-6.mol 1-Hydroxy-2-naphthoic acid Structure 1-Hydroxy-2-naphthoic acid Chemical Properties Melting point 195-200 &de

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

86-48-6 1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

1-Hydroxy-2-naphthoic acid

Cas:86-48-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Synthetic route

α-naphthol
90-15-3

α-naphthol

magnesium methyl carbonate
4861-79-4

magnesium methyl carbonate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 180℃; under 25857.4 Torr; for 6h;96%
α-naphthol
90-15-3

α-naphthol

sodium ethyl carbonate
17201-44-4

sodium ethyl carbonate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
at 140 - 190℃; under 7600 Torr; for 5h;93.4%
α-naphthol
90-15-3

α-naphthol

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With potassium hydrogencarbonate at 200℃; for 5h;60%
With salicylic acid decarboxylase from Trichosporon moniliiforme; potassium hydrogencarbonate In acetonitrile at 30℃; for 24h; pH=8.5; aq. phosphate buffer; Enzymatic reaction; regioselective reaction;
Multi-step reaction with 4 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: water; sodium hydrogencarbonate / N,N-dimethyl-formamide; diethyl ether / 0.5 h / 20 °C / Inert atmosphere
3.1: palladium diacetate; silver(I) acetate; N-tert-butoxycarbonyl-L-leucine; 2,2,2-trifluoroethanol / 1,2-dichloro-ethane / 0.08 h / 95 °C / Inert atmosphere
3.2: 18 h / 95 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / Inert atmosphere
View Scheme
1-methyl-4-nitrosobenzene
623-11-0

1-methyl-4-nitrosobenzene

4-isopropyl-benzo[h]chromen-2-one
858438-04-7

4-isopropyl-benzo[h]chromen-2-one

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-nitro-naphthalene-2-carbonitrile
1885-78-5

1-nitro-naphthalene-2-carbonitrile

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With barium dihydroxide
3-acetyl-2-methyl-benzo[h]chromen-4-one
69796-59-4

3-acetyl-2-methyl-benzo[h]chromen-4-one

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-hydroxynaphthalene-2-carbonitrile
67176-26-5

1-hydroxynaphthalene-2-carbonitrile

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With alkaline solution
sodium naphtholate
3019-88-3

sodium naphtholate

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With 1,4-dioxane
With pyridine
2-cyano-naphthalene-1-sulfonic acid ; sodium-salt

2-cyano-naphthalene-1-sulfonic acid ; sodium-salt

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
at 200 - 220℃; In der Kalischmelze;
3-benzoyl-5-chloromethyl-dihydro-furan-2-one
104095-33-2

3-benzoyl-5-chloromethyl-dihydro-furan-2-one

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With aluminium trichloride
phosgene
75-44-5

phosgene

α-naphthol
90-15-3

α-naphthol

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
Yield given. Multistep reaction;
2-(diethylamino)-4H-naphtho[1,2-b]pyran-4-one
61035-03-8

2-(diethylamino)-4H-naphtho[1,2-b]pyran-4-one

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol Heating;
6-Diazo-benzocycloheptene-5,7-dione
28591-61-9

6-Diazo-benzocycloheptene-5,7-dione

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With water
1-hydroxy-2-naphthaldehyde
574-96-9

1-hydroxy-2-naphthaldehyde

A

2-(hydroxymethyl)-1-naphthol
59648-32-7

2-(hydroxymethyl)-1-naphthol

B

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With barium dihydroxide; formaldehyd at 100 - 110℃; for 4h;A 85 % Chromat.
B 9 % Chromat.
3-ethyl-2-methyl-benzo[h]chromen-4-one
875224-19-4

3-ethyl-2-methyl-benzo[h]chromen-4-one

aqueous alkaline solution

aqueous alkaline solution

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

3-acetyl-benzo[h]chromene-2,4-dione

3-acetyl-benzo[h]chromene-2,4-dione

KOH-solution

KOH-solution

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

2,4-dioxo-3,4-dihydro-2H-benzo[h]chromene-3-carboxylic acid ethyl ester

2,4-dioxo-3,4-dihydro-2H-benzo[h]chromene-3-carboxylic acid ethyl ester

KOH-solution

KOH-solution

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

3-benzyl-4-methyl-benzo[h]chromen-2-one
95703-28-9

3-benzyl-4-methyl-benzo[h]chromen-2-one

KOH-solution

KOH-solution

A

4-Phenyl-2-butanone
2550-26-7

4-Phenyl-2-butanone

B

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

4-methyl-3-phenyl-benzo[h]chromen-2-one
861353-04-0

4-methyl-3-phenyl-benzo[h]chromen-2-one

KOH-solution

KOH-solution

A

2-methyl-benzeneacetaldehyde
10166-08-2

2-methyl-benzeneacetaldehyde

B

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

aluminium trichloride
7446-70-0

aluminium trichloride

3-benzoyl-5-chloromethyl-dihydro-furan-2-one
104095-33-2

3-benzoyl-5-chloromethyl-dihydro-furan-2-one

benzene
71-43-2

benzene

A

phenyl(1,2,3,4-tetrahydronaphthalen-1-yl)methanone
94540-41-7

phenyl(1,2,3,4-tetrahydronaphthalen-1-yl)methanone

B

1,4,5-triphenyl-pentan-1-one
112863-69-1

1,4,5-triphenyl-pentan-1-one

C

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

α-naphthol
90-15-3

α-naphthol

carbon dioxide
124-38-9

carbon dioxide

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With sodium
With sodium; toluene
With potassium carbonate under 36775.4 Torr;
With potassium hydrogencarbonate; glycerol
1-oxy-3.4-dihydro-naphthoic acid-(2)-ethyl ester

1-oxy-3.4-dihydro-naphthoic acid-(2)-ethyl ester

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With sodium; sodium cyclohexanolate; cyclohexanol at 190 - 200℃;
carbon dioxide
124-38-9

carbon dioxide

sodium naphtholate
3019-88-3

sodium naphtholate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
at 135℃;
carbon dioxide
124-38-9

carbon dioxide

alkali-α-naphtholate

alkali-α-naphtholate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With alkali sulfite
methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

alkali salt of α-naphthol

alkali salt of α-naphthol

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
Erhitzen des entstandenen Salzes im Autoklaven auf 120-140grad;
Erhitzen des entstandenen Salzes im Autoklaven auf 120-140grad;
sodium salt of/the/ 2-cyano-naphthalene-sulfonic acid-(1)

sodium salt of/the/ 2-cyano-naphthalene-sulfonic acid-(1)

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
at 200 - 220℃; durch Kalischmelze;
α-naphthol
90-15-3

α-naphthol

carbon dioxide
124-38-9

carbon dioxide

sodium

sodium

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

α-naphthol
90-15-3

α-naphthol

carbon dioxide
124-38-9

carbon dioxide

toluene
108-88-3

toluene

sodium

sodium

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-nitro-naphthalene-2-carbonitrile
1885-78-5

1-nitro-naphthalene-2-carbonitrile

aq. barium hydroxide solution

aq. barium hydroxide solution

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-hydroxy-naphthalene-2-carboxylic acid methyl ester
948-03-8

1-hydroxy-naphthalene-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With lithium hydroxide In tetrahydrofuran for 1h; Methylation; esterification; Heating;100%
Stage #1: 1-hydroxy-2-naphthoic acid With lithium hydroxide In tetrahydrofuran for 0.5h;
Stage #2: dimethyl sulfate In tetrahydrofuran for 3h; Heating;
95.9%
Stage #1: 1-hydroxy-2-naphthoic acid With triethylamine In acetone for 0.25h; Inert atmosphere;
Stage #2: dimethyl sulfate In acetone at 55℃; for 12h; Inert atmosphere;
95%
methyl iodide
74-88-4

methyl iodide

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

methyl 1-methoxy-2-naphthoate
6039-59-4

methyl 1-methoxy-2-naphthoate

Conditions
ConditionsYield
With potassium carbonate In acetone Reflux;100%
With potassium carbonate In acetone Reflux;96%
With potassium carbonate In acetone for 18h; Reflux;95%
meloxicam
71125-38-7

meloxicam

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide 1-hydroxy-2-naphthoic acid (1:1)
1174325-92-8

4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide 1-hydroxy-2-naphthoic acid (1:1)

Conditions
ConditionsYield
In tetrahydrofuran for 0.5h;100%
In tetrahydrofuran Product distribution / selectivity;
In dimethylsulfoxide-d6; water at 25 - 90℃; Solvent;71 g
camostat
59721-28-7

camostat

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

N,N-dimethyl-carbamoylmethyl p-(p-guanidinobenzoyloxy)phenylacetate xinafoate

N,N-dimethyl-carbamoylmethyl p-(p-guanidinobenzoyloxy)phenylacetate xinafoate

Conditions
ConditionsYield
In water; isopropyl alcohol at 25 - 60℃;99.1%
1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

4-bromo-1-hydroxy-2-naphthoic acid
5813-37-6

4-bromo-1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With bromine In acetic acid at 20℃;99%
With bromine; acetic acid at 20℃;99%
With bromine In acetic acid at 20℃; Inert atmosphere;92%
propan-1-ol
71-23-8

propan-1-ol

zirconium tetrapropoxide
23519-77-9

zirconium tetrapropoxide

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

Zr6O2(OC3H7)16(O2CC10H6O)2(C3H7OH)2

Zr6O2(OC3H7)16(O2CC10H6O)2(C3H7OH)2

Conditions
ConditionsYield
In propan-1-ol (argon); storing in a Schlenk tube (ambient temp., 14 d);99%
2-aminonaphthalenesulfonic acid
81-16-3

2-aminonaphthalenesulfonic acid

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

A

2-[(1-hydroxy-2-naphthalenyl)azo]-1-naphthalenesulfonic acid sodium salt
1402066-96-9

2-[(1-hydroxy-2-naphthalenyl)azo]-1-naphthalenesulfonic acid sodium salt

B

1-hydroxy-4-[(1-sulfo-2-naphthalenyl)azo]-2-naphthalenecarboxylic acid disodium salt

1-hydroxy-4-[(1-sulfo-2-naphthalenyl)azo]-2-naphthalenecarboxylic acid disodium salt

Conditions
ConditionsYield
Stage #1: 2-aminonaphthalenesulfonic acid With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 0℃; for 0.5h;
Stage #2: 1-hydroxy-2-naphthoic acid With sodium carbonate In ethanol; water at 0℃;
A 12%
B 97%
1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-acetoxy-2-naphthoic acid
6301-40-2

1-acetoxy-2-naphthoic acid

Conditions
ConditionsYield
With sulfuric acid In acetic anhydride at 100℃; for 0.166667h;97%
dimethyl sulfate
77-78-1

dimethyl sulfate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

methyl 1-methoxy-2-naphthoate
6039-59-4

methyl 1-methoxy-2-naphthoate

Conditions
ConditionsYield
With potassium carbonate In acetone at 50℃; Temperature;96%
Stage #1: 1-hydroxy-2-naphthoic acid With potassium carbonate In acetone for 0.25h; Inert atmosphere;
Stage #2: dimethyl sulfate In acetone at 55℃; for 12h; Inert atmosphere;
95%
With potassium carbonate In acetone Heating;
With potassium carbonate In acetone for 8h; Reflux;
1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

A

9-methoxy-2-amino-1,2,3,4-tetrahydroanthracene
179041-74-8

9-methoxy-2-amino-1,2,3,4-tetrahydroanthracene

B

10-methoxy-2-amino-1,2,3,4-tetrahydrophenanthrene
179041-75-9

10-methoxy-2-amino-1,2,3,4-tetrahydrophenanthrene

Conditions
ConditionsYield
A 95%
B n/a
3,6-diazabicyclo[3.1.1]heptan-3-yl(cyclopropyl) methanone
1310717-02-2

3,6-diazabicyclo[3.1.1]heptan-3-yl(cyclopropyl) methanone

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

C9H14N2O*C11H8O3
1400593-10-3

C9H14N2O*C11H8O3

Conditions
ConditionsYield
In Isopropyl acetate; water at 60℃;95%
(R)-N-(3-(5-fluoro-2-(2-fluoro-3-(methylsulfonyl)phenylamino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide

(R)-N-(3-(5-fluoro-2-(2-fluoro-3-(methylsulfonyl)phenylamino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

(R)-N-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide xinafoic acid

(R)-N-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide xinafoic acid

Conditions
ConditionsYield
Stage #1: (R)-N-(3-(5-fluoro-2-(2-fluoro-3-(methylsulfonyl)phenylamino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide In methanol; ethyl acetate at 65℃; Inert atmosphere;
Stage #2: 1-hydroxy-2-naphthoic acid In methanol; ethyl acetate at 50℃; Inert atmosphere;
95%
salmeterol
89365-50-4

salmeterol

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

salmeterol xinafoate

salmeterol xinafoate

Conditions
ConditionsYield
In acetone at 30℃; for 0.666667h; Temperature; Solvent;94.1%
In acetone at 25 - 45℃; for 1.5h;69%
In diethyl ether at 20℃; for 16h;
In isopropyl alcohol
Stage #1: salmeterol With pyrographite In methanol at 25 - 30℃; for 0.5h;
Stage #2: 1-hydroxy-2-naphthoic acid In methanol at 18 - 30℃; for 3h;
20.75 g
formaldehyd
50-00-0

formaldehyd

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

4,4'-methylenebis(1-hydroxy-2-naphthoic acid)
1175-41-3

4,4'-methylenebis(1-hydroxy-2-naphthoic acid)

Conditions
ConditionsYield
With sulfuric acid 1.) 90 deg C, 6 h, 2.) RT, 12 h;94%
ethanol
64-17-5

ethanol

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

ethyl 1-hydroxy-2-naphthoate
33950-71-9

ethyl 1-hydroxy-2-naphthoate

Conditions
ConditionsYield
With pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In toluene at 20℃; for 7.5h; Inert atmosphere;93%
With sulfuric acid
Stage #1: 1-hydroxy-2-naphthoic acid With thionyl chloride
Stage #2: ethanol With triethylamine
With sulfuric acid Reflux;
dimethyl sulfate
77-78-1

dimethyl sulfate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-methoxy-2-naphthoic acid
883-21-6

1-methoxy-2-naphthoic acid

Conditions
ConditionsYield
Stage #1: dimethyl sulfate; 1-hydroxy-2-naphthoic acid With potassium carbonate
Stage #2: With lithium hydroxide In tetrahydrofuran; water
92%
With sodium hydroxide In water
5,5-dibenzyl-2,3,4,5-tetrahydropyridine
1416767-53-7

5,5-dibenzyl-2,3,4,5-tetrahydropyridine

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

12,12-dibenzyl-10,11,12,12a-tetrahydronaphtho[2,1-e]pyrido[2,1-b][1,3]oxazin-7(9H)-one
1416767-44-6

12,12-dibenzyl-10,11,12,12a-tetrahydronaphtho[2,1-e]pyrido[2,1-b][1,3]oxazin-7(9H)-one

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine In toluene at 90℃; for 20h; Inert atmosphere;92%
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine In toluene at 90℃; for 20h;92%
benzyl bromide
100-39-0

benzyl bromide

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-benzyloxynaphthalene-2-carboxylic acid

1-benzyloxynaphthalene-2-carboxylic acid

Conditions
ConditionsYield
With potassium carbonate; tetrabutylammomium bromide In tetrahydrofuran at 30℃; for 0.166667h;91%
methanol
67-56-1

methanol

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-hydroxy-naphthalene-2-carboxylic acid methyl ester
948-03-8

1-hydroxy-naphthalene-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid90%
With sulfuric acid90%
With sulfuric acid at 80℃; for 8h;80%
1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

ethyl 1-hydroxy-2-naphthoate
33950-71-9

ethyl 1-hydroxy-2-naphthoate

Conditions
ConditionsYield
With ethanol; sulfuric acid for 8h; Reflux;90%
Multi-step reaction with 2 steps
1: SOCl2 / tetrahydrofuran / 2 h / 20 °C
2: 88 percent / 0.17 h / 120 °C / microwave irradiation
View Scheme
Multi-step reaction with 2 steps
1: petroleum ether; thionyl chloride
View Scheme
1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

2-chloro-4H-naphtho[1,2-d][1,3,2]dioxaphosphinin-4-one
352662-32-9

2-chloro-4H-naphtho[1,2-d][1,3,2]dioxaphosphinin-4-one

Conditions
ConditionsYield
With triethylamine; phosphorus trichloride In toluene at 20℃;90%
With anhydrous phosphorus trichloride In toluene75%
With Lewatit MP-62; phosphorus trichloride In toluene at 20℃; Product distribution / selectivity;75%
With triethylamine; phosphorus trichloride In toluene at 0 - 20℃; Product distribution / selectivity;74.35%
ethyl bromoacetate
105-36-2

ethyl bromoacetate

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-ethoxycarbonylmethoxynaphthalene-2-carboxylic acid
1009813-72-2

1-ethoxycarbonylmethoxynaphthalene-2-carboxylic acid

Conditions
ConditionsYield
With potassium carbonate; tetrabutylammomium bromide In tetrahydrofuran at 30℃; for 0.166667h;90%
allyl bromide
106-95-6

allyl bromide

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-(2-propenoxy)-2-naphthoic acid
1009813-71-1

1-(2-propenoxy)-2-naphthoic acid

Conditions
ConditionsYield
With potassium carbonate; tetrabutylammomium bromide In tetrahydrofuran at 30℃; for 0.166667h;90%
manganese(II) hydroxide

manganese(II) hydroxide

water
7732-18-5

water

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

tetraaquabis(1-hydroxy-2-naphthoato-κO)manganese(II)
869582-71-8

tetraaquabis(1-hydroxy-2-naphthoato-κO)manganese(II)

Conditions
ConditionsYield
In water suspn. of Mn(OH)2 in H2O added to suspn. of acid in water; mixt. heated at 313 K for 6 wk; sepd. by decantation; dried at room temp.;90%
methyl iodide
74-88-4

methyl iodide

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

1-methoxy-2-naphthoic acid
883-21-6

1-methoxy-2-naphthoic acid

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 10h; Cooling with ice;90%
1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

C22H14N2O3

C22H14N2O3

Conditions
ConditionsYield
With Vilsmeier reagent; hydrazine hydrate; triethylamine In acetonitrile at 20℃; for 8h;90%
4-methyl-1,2-diaminobenzene
496-72-0

4-methyl-1,2-diaminobenzene

1-hydroxy-2-naphthoic acid
86-48-6

1-hydroxy-2-naphthoic acid

2-(5-methyl-1H-benzo[d]imidazol-2-yl)naphthalen-1-ol

2-(5-methyl-1H-benzo[d]imidazol-2-yl)naphthalen-1-ol

Conditions
ConditionsYield
With polyphosphoric acid for 0.166667h; Microwave irradiation;90%

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