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Hefei TNJ chemical industry co.,ltd

Introduction 2,2,4-Trimethyl-1,3-pentanediol TMPD CAS (144-19-4) is a kind of white crystal, can soluble in alcohol, ketone, aromatic hydrocarbon solvents, soluble in water and fat hydrocarbon. It mainly used in the manufacture of polyester resin,

2,2,4-Trimethyl-1,3-pentanediol TMPD CAS (144-19-4)

Cas:144-19-4

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,2,4-trimethylpentane-1,3-diol

Cas:144-19-4

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory price Cosmetic TRIMETHYL-1,3-PENTANEDIOL 144-19-4 Manufacturer

Cas:144-19-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM----2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 144-19-4 with best price

Cas:144-19-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Specifications 2 2 4 - trimethyl-1 3-pentanediol/144-19-4 Molecular Formula C8H18O2 Molecular Weight 146.23 CAS Registry Number 144-19-4 2,2,4 - trimethyl-1,3-pentanediol/144-19-4 Application: 2,2,4-Trimethylpentane

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,3-Pentanediol,2,2,4-trimethyl- 144-19-4

Cas:144-19-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2,2,4-Trimethyl-1,3-pentanediol CAS:144-19-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality org

2,2,4-Trimethyl-1,3-pentanediol CAS:144-19-4

Cas:144-19-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,3-Pentanediol,2,2,4-trimethyl-

Cas:144-19-4

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS

China Largest Manufacturer factory sales 2,2,4-Trimethyl-1,3-pentanediol CAS 144-19-4

Cas:144-19-4

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,3-Pentanediol,2,2,4-trimethyl-

Cas:144-19-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,3-Pentanediol,2,2,4-trimethyl-

Cas:144-19-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2,2,4-Trimethyl-1,3-pentanediol TMPD

Cas:144-19-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Factory Sells2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:0

Negotiable

Type:Trading Company

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,2,4-Trimethylpentane-1,3-diol

Cas:144-19-4

Min.Order:0

Negotiable

Type:Manufacturers

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:1 Kilogram

Negotiable

Type:Other

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Hebei Mojin Biotechnology Co.,Ltd

We produce carbomer by our own factory,carbomer 940 is our best seller.It is used for cosmetic and medical.And we also become agent for lubrizol.Our carbomer 940 get high viscosity and good transparency.The price will depond on the market,surely supp

1,3-Pentanediol,2,2,4-trimethyl-

Cas:144-19-4

Min.Order:0

Negotiable

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2,2,4-trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

tris(2-ethylhexyl) 2-(acetyloxy)propane-1,2,3-tricarboxylate

Cas:144-19-4

Min.Order:0

Negotiable

Type:Other

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JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

2,2,4-Trimethylpentane-1,3-Diol

Cas:144-19-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 2,2,4-Trimethyl-1,3-pentanediol (TMPD) T32430 250g

Cas:144-19-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2,2,4-TriMethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:0

Negotiable

Type:Manufacturers

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Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

2,2,4-Trimethyl-1,3-pentanediol

Cas:144-19-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

texanol
77-68-9

texanol

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

2,2,4-trimethyl-1,3-pentanediol diisobutyrate
6846-50-0

2,2,4-trimethyl-1,3-pentanediol diisobutyrate

Conditions
ConditionsYield
With Cr2O3/SO42 solid acid catalyst at 160℃; for 6h; Reagent/catalyst; Temperature;A n/a
B 93%
isobutyraldehyde
78-84-2

isobutyraldehyde

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
With nickel In sodium hydroxide at 20℃; Electrochemical reaction;92%
With sodium hydroxide
With calcium hydroxide
ethene
74-85-1

ethene

isobutyraldehyde
78-84-2

isobutyraldehyde

2,4-dimethyl-1,3-pentane diol

2,4-dimethyl-1,3-pentane diol

B

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
Stage #1: ethene; isobutyraldehyde With carbon monoxide; hydrogen; triphenylphosphine; acetylacetonatodicarbonylrhodium(l); L-proline In N,N-dimethyl-formamide at 5℃; under 22502.3 Torr; for 48h;
Stage #2: With sodium tetrahydroborate In methanol; N,N-dimethyl-formamide at 0℃; for 0.666667h; Further stages.;
A n/a
B n/a
C 76%
7-Isopropyl-8,8-dimethyl-8,9-dihydro-7H-6,10-dioxabenzocyclononene-5,11-dione
221319-52-4

7-Isopropyl-8,8-dimethyl-8,9-dihydro-7H-6,10-dioxabenzocyclononene-5,11-dione

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
48%
5,5-dimethyl-2,6-bis(propan-2-yl)-1,3-dioxan-4-ol
16889-18-2

5,5-dimethyl-2,6-bis(propan-2-yl)-1,3-dioxan-4-ol

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
With water; nickel at 50 - 85℃; Hydrogenation;
With hydrogen; chromium nickel
Multi-step reaction with 2 steps
1: aqueous acetic acid / Abdestillieren des entstehenden Isobutyraldehyds
2: Raney nickel; water / 125 - 165 °C / Hydrogenation
View Scheme
3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
With sodium amalgam; ethanol; sulfuric acid
With water; nickel at 125 - 165℃; Hydrogenation;
3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

isobutyric Acid
79-31-2

isobutyric Acid

Conditions
ConditionsYield
With potassium hydroxide zuletzt bei Siedetemperatur;
isobutyraldehyde
78-84-2

isobutyraldehyde

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

Conditions
ConditionsYield
With potassium hydroxide
3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
With sodium hydroxide at 200℃;
With water; calcium carbonate at 150℃; under 40452.9 Torr;
ethyl 2,2,4-trimethyl-3-hydroxyvalerate
7403-65-8

ethyl 2,2,4-trimethyl-3-hydroxyvalerate

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride
2,2,4-trimethyl-1,3-pentanediol diisobutyrate
6846-50-0

2,2,4-trimethyl-1,3-pentanediol diisobutyrate

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
With sodium hydroxide In methanol
sodium amide

sodium amide

isobutyraldehyde
78-84-2

isobutyraldehyde

acetylene
74-86-2

acetylene

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

4-methylpent-1-yn-3-ol
565-68-4

4-methylpent-1-yn-3-ol

C

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

Conditions
ConditionsYield
at 20 - 25℃;
diethyl ether
60-29-7

diethyl ether

sodium amide

sodium amide

isobutyraldehyde
78-84-2

isobutyraldehyde

acetylene
74-86-2

acetylene

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

4-methylpent-1-yn-3-ol
565-68-4

4-methylpent-1-yn-3-ol

C

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

D

isobutyl alcohol(?)

isobutyl alcohol(?)

Conditions
ConditionsYield
at 20 - 25℃;
2.2.4-trimethyl-pentanediol-(1.3)-isobutyrate-(1)

2.2.4-trimethyl-pentanediol-(1.3)-isobutyrate-(1)

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

Conditions
ConditionsYield
durch Verseifen;
With alkaline solution
3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

KOH-solution

KOH-solution

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

ethanol
64-17-5

ethanol

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

sulfuric acid
7664-93-9

sulfuric acid

sodium amalgam

sodium amalgam

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

2,2,4-trimethyl-3-hydroxyvaleric acid
35763-45-2

2,2,4-trimethyl-3-hydroxyvaleric acid

alcoholic KOH-solution

alcoholic KOH-solution

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

isobutyric Acid
79-31-2

isobutyric Acid

texanol
77-68-9

texanol

alcoholic potash

alcoholic potash

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

isobutyric Acid
79-31-2

isobutyric Acid

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

aqueous methanolic KOH

aqueous methanolic KOH

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

isobutyric Acid
79-31-2

isobutyric Acid

Conditions
ConditionsYield
at 25℃;
3-(α-hydroxy-isobutoxy)-2,2,4-trimethyl-valeraldehyde
43079-80-7

3-(α-hydroxy-isobutoxy)-2,2,4-trimethyl-valeraldehyde

ethanolic KOH-solution

ethanolic KOH-solution

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

isobutyric Acid
79-31-2

isobutyric Acid

2,4-dihydroxy-3,3,5-trimethyl-hexanenitrile
5333-89-1

2,4-dihydroxy-3,3,5-trimethyl-hexanenitrile

KOH-solution

KOH-solution

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

hydrogen cyanide
74-90-8

hydrogen cyanide

C

isobutyric Acid
79-31-2

isobutyric Acid

2,2,4,4-tetramethyl-1,3-cyclobutanedione
933-52-8

2,2,4,4-tetramethyl-1,3-cyclobutanedione

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

2,2,4-trimethyl-3-oxo-1-pentanol
15904-30-0

2,2,4-trimethyl-3-oxo-1-pentanol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

E

3-hydroxy-2,2,4,4-tetramethylcyclobutane-1-one
4916-59-0

3-hydroxy-2,2,4,4-tetramethylcyclobutane-1-one

Conditions
ConditionsYield
With hydrogen; A280 cobalt on alumina catalyst In isobutyl isobutanoate at 165℃; under 25877.6 - 75007.5 Torr; for 2h; Product distribution / selectivity;
With hydrogen; A280 cobalt on alumina catalyst promoted with Ir(OAc)x In isobutyl isobutanoate at 135 - 165℃; under 25877.6 - 75007.5 Torr; for 2h; Product distribution / selectivity;
With hydrogen; G-96B-RS 62percent nickel on kieselguhr catalyst In isobutyl isobutanoate at 160℃; under 46504.7 Torr; for 3h; Product distribution / selectivity;
2,2,4,4-tetramethyl-1,3-cyclobutanedione
933-52-8

2,2,4,4-tetramethyl-1,3-cyclobutanedione

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

D

3-hydroxy-2,2,4,4-tetramethylcyclobutane-1-one
4916-59-0

3-hydroxy-2,2,4,4-tetramethylcyclobutane-1-one

Conditions
ConditionsYield
With hydrogen; G-67A 20percent cobalt on silica catalyst In isobutyl isobutanoate at 135℃; under 25877.6 Torr; for 2h; Product distribution / selectivity;
With hydrogen; cesium-promoted copper on silica catalyst In isobutyl isobutanoate at 135℃; under 75007.5 Torr; for 2h; Product distribution / selectivity;
2,2,4,4-tetramethyl-1,3-cyclobutanedione
933-52-8

2,2,4,4-tetramethyl-1,3-cyclobutanedione

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

2,2,4-trimethyl-3-oxo-1-pentanol
15904-30-0

2,2,4-trimethyl-3-oxo-1-pentanol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

Conditions
ConditionsYield
With hydrogen; chromium-promoted KL2015-T5 copper on zinc oxide catalyst In isobutyl isobutanoate at 135℃; under 25877.6 - 75007.5 Torr; for 2h; Product distribution / selectivity;
2,2,4,4-tetramethyl-1,3-cyclobutanedione
933-52-8

2,2,4,4-tetramethyl-1,3-cyclobutanedione

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

Conditions
ConditionsYield
With hydrogen; cesium-promoted copper on silica catalyst In isobutyl isobutanoate at 165℃; under 25877.6 - 75007.5 Torr; for 2h; Product distribution / selectivity;
With hydrogen; chromium-promoted KL2015-T5 copper on zinc oxide catalyst In isobutyl isobutanoate at 135 - 165℃; under 75007.5 Torr; for 2h; Product distribution / selectivity;
trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

trans-2,2,4,4-tetramethylcyclobutane-1,3-diol

A

2,2,4-trimethyl-1-pentanol
123-44-4

2,2,4-trimethyl-1-pentanol

B

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

C

2,2,4-trimethyl-3-pentanol
5162-48-1

2,2,4-trimethyl-3-pentanol

D

2,4-dimethyl-3-pentanol
600-36-2

2,4-dimethyl-3-pentanol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

cis-2,2,4,4-tetramethylcyclobutane-1,3-diol

Conditions
ConditionsYield
With isobutyl isobutanoate; 5 % platinum on carbon at 50 - 200℃; under 5250.53 - 21002.1 Torr; Product distribution / selectivity; Inert atmosphere;
isobutyraldehyde
78-84-2

isobutyraldehyde

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

texanol
77-68-9

texanol

C

2,2,4-trimethyl-1,3-pentanediol diisobutyrate
6846-50-0

2,2,4-trimethyl-1,3-pentanediol diisobutyrate

D

2-methylpropionic acid 3-hydroxy-2,2-dimethyl-1-(1-methylethyl)propyl ester
18491-15-1

2-methylpropionic acid 3-hydroxy-2,2-dimethyl-1-(1-methylethyl)propyl ester

E

isobutyric Acid
79-31-2

isobutyric Acid

Conditions
ConditionsYield
With sodium hydroxide In water at 60℃; for 4h; Concentration; Overall yield = 63.6 %Chromat.;
isobutyraldehyde
78-84-2

isobutyraldehyde

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

C

texanol
77-68-9

texanol

D

2-methylpropionic acid 3-hydroxy-2,2-dimethyl-1-(1-methylethyl)propyl ester
18491-15-1

2-methylpropionic acid 3-hydroxy-2,2-dimethyl-1-(1-methylethyl)propyl ester

E

isobutyric Acid
79-31-2

isobutyric Acid

Conditions
ConditionsYield
Stage #1: isobutyraldehyde With sodium hydroxide at 60℃; for 4h;
Stage #2: With hydrogenchloride Concentration; Overall yield = 59.3 %Chromat.;
isobutyraldehyde
78-84-2

isobutyraldehyde

A

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

B

texanol
77-68-9

texanol

C

2-methylpropionic acid 3-hydroxy-2,2-dimethyl-1-(1-methylethyl)propyl ester
18491-15-1

2-methylpropionic acid 3-hydroxy-2,2-dimethyl-1-(1-methylethyl)propyl ester

D

isobutyric Acid
79-31-2

isobutyric Acid

Conditions
ConditionsYield
Stage #1: isobutyraldehyde With sodium hydroxide at 60℃; for 4h;
Stage #2: With hydrogenchloride Concentration; Overall yield = 85.4 %Chromat.;
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

2,2,4-trimethyl-3-oxo-1-pentanol
15904-30-0

2,2,4-trimethyl-3-oxo-1-pentanol

Conditions
ConditionsYield
With tert.-butylhydroperoxide; [π-C5H5N(+)(CH2)15CH3]3(PMo12O40)(3-) In benzene for 24h; Heating;100%
With dihydrogen peroxide In water; tert-butyl alcohol at 80℃; for 12h; chemoselective reaction;99%
With iron(III) chloride; 1,1,1,3',3',3'-hexafluoro-propanol; oxygen; nitric acid at 20℃; for 5h; Catalytic behavior;96%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

benzoyl chloride
98-88-4

benzoyl chloride

2,2,4-trimethyl-1,3-pentanediol monobenzoate

2,2,4-trimethyl-1,3-pentanediol monobenzoate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0℃; for 2h; Inert atmosphere;100%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

Conditions
ConditionsYield
With 1-methyl-1H-imidazole; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; 4,4'-Dimethoxy-2,2'-bipyridin; 9-azabicyclo[3.3.1]nonane N-oxyl; oxygen In acetonitrile at 20℃; for 0.5h;98%
With 1‐methyl‐2‐azaadamantane‐N‐oxyl; sodium hypochlorite; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h;96%
With sodium hypochlorite; 1,5-dimethyl-9-azanoradamantane N-oxyl; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h; Reagent/catalyst; Inert atmosphere;96%
4-(4-t-butylphenylsulphinyl)acetophenone

4-(4-t-butylphenylsulphinyl)acetophenone

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

C26H36O3S

C26H36O3S

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 105℃; for 7h; Inert atmosphere;98%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

butyric acid
107-92-6

butyric acid

C17H32O4

C17H32O4

Conditions
ConditionsYield
With potassium dihydrogenphosphate; sodium hydrogensulfate monohydrate at 160℃; for 8h; Reagent/catalyst; Inert atmosphere;97%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

chlorodimethyl(1,1,2-trimethylpropyl)silane
67373-56-2

chlorodimethyl(1,1,2-trimethylpropyl)silane

dimethyl(3-hydroxy-2,2,4-trimethylpentyloxy)(1,1,2-trimethylpropyl)silane
1061244-98-1

dimethyl(3-hydroxy-2,2,4-trimethylpentyloxy)(1,1,2-trimethylpropyl)silane

Conditions
ConditionsYield
With 1-methyl-1H-imidazole; iodine In dichloromethane at 20℃; for 0.0833333h;96%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

1-(2-methyl-2-propenyloxy)-2,2,4-trimethylpentan-3-ol
526218-21-3

1-(2-methyl-2-propenyloxy)-2,2,4-trimethylpentan-3-ol

Conditions
ConditionsYield
Stage #1: 2,2,4-trimethylpentan-1,3-diol With sodium hydroxide; tetrabutylammomium bromide In water at 50℃;
Stage #2: 3-Chloro-2-methylpropene In water at 100℃; for 3.83333h;
94.1%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

(1S,2R)-1,2-diphenylethane-1,2-diol
579-43-1

(1S,2R)-1,2-diphenylethane-1,2-diol

4-isopropyl-5,5-dimethyl-2-phenyl-1,3-dioxane
24571-18-4

4-isopropyl-5,5-dimethyl-2-phenyl-1,3-dioxane

Conditions
ConditionsYield
With PTAB; N-benzyl-N,N,N-triethylammonium chloride; antimony(III) bromide In dimethyl sulfoxide at 20℃; for 61h;94%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

allyl bromide
106-95-6

allyl bromide

1,3-bis(allyloxy)-2,2,4-trimethylpentane
5511-07-9

1,3-bis(allyloxy)-2,2,4-trimethylpentane

Conditions
ConditionsYield
Stage #1: 2,2,4-trimethylpentan-1,3-diol With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: allyl bromide In tetrahydrofuran at 20℃; Inert atmosphere; Reflux;
93%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

2,2,4-trimethyl-3-hydroxyvaleric acid
35763-45-2

2,2,4-trimethyl-3-hydroxyvaleric acid

Conditions
ConditionsYield
With sodium hypochlorite; sodium chlorite; 1,5-dimethyl-9-azanoradamantane N-oxyl In aq. phosphate buffer; acetonitrile at 25℃; for 7h; pH=6.8; Catalytic behavior; Reagent/catalyst;92%
With potassium permanganate; water
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

A

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

B

3-oxo-2,2,4-trimetheyl-1-pentanal
1482-01-5

3-oxo-2,2,4-trimetheyl-1-pentanal

Conditions
ConditionsYield
With sodium hypochlorite; C9H14NO; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h; Inert atmosphere;A 92%
B 6%
With sodium hypochlorite; 1,5-dimethyl-9-azanoradamantane N-oxyl; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h;A 69%
B 17%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

methyl 3-hydroxy-2,2,4-trimethylpentanoate
67498-08-2

methyl 3-hydroxy-2,2,4-trimethylpentanoate

Conditions
ConditionsYield
Stage #1: 2,2,4-trimethylpentan-1,3-diol With sodium hypochlorite; sodium chlorite; 1,5-dimethyl-9-azanoradamantane N-oxyl In aq. phosphate buffer; water; acetonitrile for 7h; pH=6.8; Inert atmosphere;
Stage #2: diazomethane In diethyl ether Reagent/catalyst; Inert atmosphere;
92%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

trans-Stilbene oxide
1439-07-2

trans-Stilbene oxide

4-isopropyl-5,5-dimethyl-2-phenyl-1,3-dioxane
24571-18-4

4-isopropyl-5,5-dimethyl-2-phenyl-1,3-dioxane

Conditions
ConditionsYield
With PTAB; N-benzyl-N,N,N-triethylammonium chloride; antimony(III) bromide In dimethyl sulfoxide at 20℃; for 46h;91%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

benzoic acid
65-85-0

benzoic acid

2,2,4-Trimethyl-1,3-pentanediol Dibenzoate
68052-23-3

2,2,4-Trimethyl-1,3-pentanediol Dibenzoate

Conditions
ConditionsYield
With H2SO4/TiO2-La2O3-solid acid catalyst In dibutyl ether at 170 - 180℃; for 10h;90.5%
tert-butyl acetoacetate
1694-31-1

tert-butyl acetoacetate

2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

2,2,4-Trimethylpentane-1,3-diol bisacetoacetate
58213-74-4

2,2,4-Trimethylpentane-1,3-diol bisacetoacetate

Conditions
ConditionsYield
In xylene for 0.5h; Heating;87%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

acetic anhydride
108-24-7

acetic anhydride

1,3-diacetoxy-2,2,4-trimethyl-pentane
4100-09-8

1,3-diacetoxy-2,2,4-trimethyl-pentane

Conditions
ConditionsYield
bismuth(lll) trifluoromethanesulfonate In acetonitrile at 20℃; for 1h;87%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

3-oxo-2,2,4-trimetheyl-1-pentanal
1482-01-5

3-oxo-2,2,4-trimetheyl-1-pentanal

Conditions
ConditionsYield
With sodium hypochlorite; 1-methyl-2-azaadamantane-N-oxyl; tetrabutylammomium bromide; potassium bromide In dichloromethane; sodium hydrogencarbonate at 0℃; for 0.333333h;87%
With 1‐methyl‐2‐azaadamantane‐N‐oxyl; sodium hypochlorite; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h;87%
With sodium hypochlorite; 3-methyl-4-oxa-5-azahomoadamantane; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h; Inert atmosphere;84%
With polystyrene-supported oxorhenium catalyst activated by iPrOH; dimethyl sulfoxide In toluene for 15h; Heating; Dean-Stark apparatus;82%
With sodium hypochlorite; C8H12NO; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h; Inert atmosphere;72%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

3-hydroxy-2,2,4-trimethylpentanenitrile
59346-56-4

3-hydroxy-2,2,4-trimethylpentanenitrile

Conditions
ConditionsYield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; ammonium acetate In water; acetonitrile at 20℃; for 8h; chemoselective reaction;87%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

1,1,2-triphenyl-1,2-ethanediol
6296-95-3

1,1,2-triphenyl-1,2-ethanediol

A

benzophenone
119-61-9

benzophenone

B

4-isopropyl-5,5-dimethyl-2-phenyl-1,3-dioxane
24571-18-4

4-isopropyl-5,5-dimethyl-2-phenyl-1,3-dioxane

Conditions
ConditionsYield
With PTAB; N-benzyl-N,N,N-triethylammonium chloride; antimony(III) bromide In dimethyl sulfoxide at 20℃; for 42h;A 86%
B 84%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

diphenylsilanediol
947-42-2

diphenylsilanediol

boric acid
11113-50-1

boric acid

(C6H5)2Si(OBO2C3H3(CH3)2CH(CH3)2)2
255849-43-5

(C6H5)2Si(OBO2C3H3(CH3)2CH(CH3)2)2

Conditions
ConditionsYield
In toluene byproducts: H2O; inert atmosphere; refluxing (8 h); evapn., hexanes addn., filtering, pptn. on concg. (-22°C, severalh); elem. anal.;85.2%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

isobutyryl chloride
79-30-1

isobutyryl chloride

2,2,4-trimethyl-1,3-pentanediol diisobutyrate
6846-50-0

2,2,4-trimethyl-1,3-pentanediol diisobutyrate

Conditions
ConditionsYield
With zinc(II) chloride In dichloromethane at 0 - 40℃; Molecular sieve;85.2%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

2-(4-bromomethyl-2-methoxyphenyl)benzothiazole
949913-33-1

2-(4-bromomethyl-2-methoxyphenyl)benzothiazole

1-[4-(benzothiazol-2-yl)-3-methoxybenzyloxyl]-2,2,4-trimethylpentan-3-ol
1225265-83-7

1-[4-(benzothiazol-2-yl)-3-methoxybenzyloxyl]-2,2,4-trimethylpentan-3-ol

Conditions
ConditionsYield
Stage #1: 2,2,4-trimethylpentan-1,3-diol With sodium hydride In tetrahydrofuran at 0 - 20℃; for 0.666667h; Inert atmosphere;
Stage #2: 2-(4-bromomethyl-2-methoxyphenyl)benzothiazole In tetrahydrofuran; N,N-dimethyl-formamide at 0 - 20℃; for 2h; Williamson synthesis; Inert atmosphere;
85%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

A

methanol
67-56-1

methanol

B

4-isopropyl-5,5-dimethyl-[1,3]dioxan-2-one
32368-14-2

4-isopropyl-5,5-dimethyl-[1,3]dioxan-2-one

Conditions
ConditionsYield
zinc(II) acetylacetonate at 20 - 155℃; for 10.5h; Product distribution / selectivity; Neat (no solvent); Reflux/azeotropic distillation;A n/a
B 84.9%
zinc diacetate at 20 - 155℃; for 12.5h; Product distribution / selectivity; Neat (no solvent); Reflux/azeotropic distillation;A n/a
B 81.3%
tin(II) octanoate at 20 - 155℃; for 18h; Product distribution / selectivity; Neat (no solvent); Reflux/azeotropic distillation;A n/a
B 78.2%
zinc stearate at 20 - 155℃; for 18h; Product distribution / selectivity; Neat (no solvent); Reflux/azeotropic distillation;A n/a
B 73.5%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

A

3-hydroxy-2,2,4-trimethyl-pentanal
918-79-6

3-hydroxy-2,2,4-trimethyl-pentanal

B

2,2,4-trimethyl-3-hydroxyvaleric acid
35763-45-2

2,2,4-trimethyl-3-hydroxyvaleric acid

Conditions
ConditionsYield
With sodium hypochlorite; 1,5-dimethyl-9-azanoradamantane N-oxyl; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at 0℃; for 0.333333h; Reagent/catalyst; Inert atmosphere;A 81%
B 6%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

1,1,3,3-tetraphenyldisiloxane-1,3-diol
1104-93-4

1,1,3,3-tetraphenyldisiloxane-1,3-diol

boric acid
11113-50-1

boric acid

O(Si(C6H5)2OBO2C3H3(CH3)2CH(CH3)2)2
255849-48-0

O(Si(C6H5)2OBO2C3H3(CH3)2CH(CH3)2)2

Conditions
ConditionsYield
In not given byproducts: H2O; inert atmosphere; elem. anal.;80%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

trans-2-chloro-4-isopropyl-5,5-dimethyl-1,3,2-dioxaphosphorinane
80812-98-2, 95115-80-3, 99835-52-6, 103228-82-6

trans-2-chloro-4-isopropyl-5,5-dimethyl-1,3,2-dioxaphosphorinane

Conditions
ConditionsYield
With triethylamine; phosphorus trichloride In benzene for 4h; Ambient temperature;76%
With triethylamine; phosphorus trichloride In diethyl ether for 2h; Ambient temperature;71%
2,2,4-trimethylpentan-1,3-diol
144-19-4

2,2,4-trimethylpentan-1,3-diol

C16H32O4Si

C16H32O4Si

Conditions
ConditionsYield
With silica gel; sodium hydroxide for 24h; Reagent/catalyst; Inert atmosphere;73%
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