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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

1-ETHOXY-2,2-DIFLUOROETHANOL

Cas:148992-43-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-ethoxy-2,2-difluoroethanol

Cas:148992-43-2

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Difluoroacetaldehyde ethyl hemiacetal

Cas:148992-43-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

DIFLUOROACETALDEHYDE ETHYL HEMIACETAL

Cas:148992-43-2

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 148992-43-2 with best price

Cas:148992-43-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

Hangzhou Fanda Chemical Co.,Ltd (FandaChem) , a China-based chemical company, specialize in exporting Difluoroacetaldehyde Ethyl Hemiacetal CAS:148992-43-2 ;Please contact us by email freely. We are leading exporter in China. If yo

Difluoroacetaldehyde Ethyl Hemiacetal CAS:148992-43-2 from Fandachem

Cas:148992-43-2

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

1-Ethoxy-2,2-difluoroethanol

Cas:148992-43-2

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Difluoroacetaldehyde Ethyl Hemiacetal

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Difluoroacetaldehyde Ethyl HeMiacetal

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

DIFLUOROACETALDEHYDE ETHYL HEMIACETAL

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Difluoroacetaldehyde Ethyl HeMiacetal

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

1-Ethoxy-2,2-difluoroethanol

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

DIFLUOROACETALDEHYDE ETHYL HEMIACETAL

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

1-Ethoxy-2,2-difluoroethanol

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

1-Ethoxy-2,2-difluoroethanol

Cas:148992-43-2

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

DIFLUOROACETALDEHYDE ETHYL HEMIACETAL

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Fine Chemicals Co., Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & CommercialHenan Fine Chemicals Co., LTD. is a diversified technology - oriented integrated company, which mainly concentrates on fine chemicals. Our company is committed to becom

1-ETHOXY-2,2-DIFLUOROETHANOL

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 1-Ethoxy-2,2-difluoroethanol, CAS:148992-43-2 with the most competitive price and the

1-Ethoxy-2,2-difluoroethanol

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Weihai Moochun Bio-Tech Co., Ltd.

high quality;competitive price Storage:keep sealed and keep from direct light Package:Sample: 50g/ bottle 100g/ bottle 1000g/ bottle bulk: 25kg/drum 50kg/drum 539kg/drum Application:Scientific research Transportation:For small batches, they will

DIFLUOROACETALDEHYDE ETHYL HEMIACETAL

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

SUZHOU AUSUN CHEMICAL CO., LTD。

Factory price in stock Package:25kg/drum Application:Chemical raw materials, pharmaceutical intermediates etc. Transportation:sea transportation Port:SHANGHAI

Difluoroacetaldehyde Ethyl Hemiacetal

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

1-Ethoxy-2,2-difluoroethanol

Cas:148992-43-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

ethyl difluoroacetate
454-31-9

ethyl difluoroacetate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at -78℃; for 2.75h;100%
With lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at -78℃; for 3h;60%
With lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at -78℃; for 3h; Reagent/catalyst; Solvent;60%
ethanol
64-17-5

ethanol

ethyl difluoroacetate
454-31-9

ethyl difluoroacetate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride 1.) Et2O, THF, -78 deg C, 3 h, 2.) Et2O, THF, rt, 2 h;
ethyl difluoroacetate
454-31-9

ethyl difluoroacetate

A

difluoroethanol
359-13-7

difluoroethanol

B

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

Conditions
ConditionsYield
With sodium tetrahydroborate; cerium(III) chloride In methanol; water at -15℃; for 1h; Title compound not separated from byproducts;
With ruthenium(bis[2‐(ethylsulfanyl)ethyl]amine)(dichloro)(triphenylphosphine); hydrogen; sodium ethanolate In ethanol at 25℃; under 22502.3 Torr; for 4h; Reagent/catalyst; Solvent; Temperature; Pressure;
difluoroacetic acid methyl ester
433-53-4

difluoroacetic acid methyl ester

acetic acid
64-19-7

acetic acid

A

difluoroacetaldehyde methyl hemiacetal
129660-32-8

difluoroacetaldehyde methyl hemiacetal

B

C4H6F4O2

C4H6F4O2

C

C6H10F4O3

C6H10F4O3

D

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

Conditions
ConditionsYield
Stage #1: difluoroacetic acid methyl ester With [carbonylchlorohydrido{bis[2-(diphenylphosphinomethyl)ethyl]amino}ethylamino] ruthenium(II); hydrogen; sodium methylate In methanol at 15℃; under 7500.75 Torr; for 8h; Large scale;
Stage #2: acetic acid In methanol at 66℃; under 15.7516 Torr; Reagent/catalyst; Solvent; Pressure; Temperature; Large scale;
ethyl difluoroacetate
454-31-9

ethyl difluoroacetate

A

difluoroethanol
359-13-7

difluoroethanol

B

difluoroacetaldehyde methyl hemiacetal
129660-32-8

difluoroacetaldehyde methyl hemiacetal

C

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

Conditions
ConditionsYield
With [carbonylchlorohydrido{bis[2-(diphenylphosphinomethyl)ethyl]amino}ethylamino] ruthenium(II); hydrogen; sodium methylate In methanol at 15℃; under 7500.75 Torr; for 8.16667h; Pressure;
para-xylene
106-42-3

para-xylene

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

1,1-difluoro-2,2-bis(2',5'-dimethylphenyl)ethane
1314534-86-5

1,1-difluoro-2,2-bis(2',5'-dimethylphenyl)ethane

Conditions
ConditionsYield
With boron trifluoride monohydrate In water at 0℃; for 0.5h; Friedel Crafts hydroxyalkylation;98%
2-nitropropane
79-46-9

2-nitropropane

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

1,1-difluoro-3-methyl-3-nitro-2-butanol

1,1-difluoro-3-methyl-3-nitro-2-butanol

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran96%
With potassium carbonate In tetrahydrofuran Ambient temperature;82%
3-(tertbutyldimethylsiloxyl)propylamine
115306-75-7

3-(tertbutyldimethylsiloxyl)propylamine

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(E)-N-(3-((tert-butyldimethylsilyl)oxy)propyl)-2,2-difluoroethan-1-imine

(E)-N-(3-((tert-butyldimethylsilyl)oxy)propyl)-2,2-difluoroethan-1-imine

Conditions
ConditionsYield
In benzene for 18h; Dean-Stark; Reflux;94%
Glycine tert-butyl ester
6456-74-2

Glycine tert-butyl ester

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

tert-butyl (E)-2-((2,2-difluoroethylidene)amino)acetate

tert-butyl (E)-2-((2,2-difluoroethylidene)amino)acetate

Conditions
ConditionsYield
In benzene for 18h; Dean-Stark; Reflux;93%
p-nitrophenoxyamine
33543-55-4

p-nitrophenoxyamine

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

C8H6F2N2O3

C8H6F2N2O3

Conditions
ConditionsYield
at 50℃; for 24h; Sealed tube; Acidic conditions;93%
nitroacetic acid ethyl ester
626-35-7

nitroacetic acid ethyl ester

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

ethyl 4,4-difluoro-3-hydroxy-2-nitro-2-butanoate

ethyl 4,4-difluoro-3-hydroxy-2-nitro-2-butanoate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran Ambient temperature;92%
With 2,8,9-(i-Pr)3-2,5,8,9-tetraza-1-phosphabicyclo[3,3,3]undecen In tetrahydrofuran
4-methoxy-aniline
104-94-9

4-methoxy-aniline

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

N-(2,2-difluoroethylidene)-4-methoxyaniline

N-(2,2-difluoroethylidene)-4-methoxyaniline

Conditions
ConditionsYield
In toluene at 100℃; for 3h;91%
methyl 2-acetylamino-2-(dimethoxyphosphinyl)acetate
89524-99-2

methyl 2-acetylamino-2-(dimethoxyphosphinyl)acetate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(Z)-2-Acetylamino-4,4-difluoro-but-2-enoic acid methyl ester

(Z)-2-Acetylamino-4,4-difluoro-but-2-enoic acid methyl ester

Conditions
ConditionsYield
With potassium tert-butylate In dichloromethane91%
methyl 4-nitrobutyrate
13013-02-0

methyl 4-nitrobutyrate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

methyl 6,6-difluoro-5-hydroxy-4-nitrohexanoate

methyl 6,6-difluoro-5-hydroxy-4-nitrohexanoate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran Ambient temperature;90%
para-difluorobenzene
540-36-3

para-difluorobenzene

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

1,1-difluoro-2,2-bis(2',5'-difluorophenyl)ethane
1314534-92-3

1,1-difluoro-2,2-bis(2',5'-difluorophenyl)ethane

Conditions
ConditionsYield
With boron trifluoride monohydrate In water at 20℃; for 5h; Friedel Crafts hydroxyalkylation;90%
O-(2-nitrophenyl)hydroxylamine
38100-30-0

O-(2-nitrophenyl)hydroxylamine

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

C8H6F2N2O3

C8H6F2N2O3

Conditions
ConditionsYield
at 50℃; for 24h; Sealed tube; Acidic conditions;90%
1-(benzo[d][1,3]dioxol-5-yl)allyl acetate
34627-78-6

1-(benzo[d][1,3]dioxol-5-yl)allyl acetate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(2S,3R)-3-(benzo[d][1,3]dioxol-5-yl)-1,1-difluoropent-4-en-2-ol

(2S,3R)-3-(benzo[d][1,3]dioxol-5-yl)-1,1-difluoropent-4-en-2-ol

Conditions
ConditionsYield
With C49H36Cl2IrN2O6P2; potassium carbonate In tetrahydrofuran; ethanol; isopropyl alcohol at 100℃; for 24h; Inert atmosphere; Sealed tube; Molecular sieve; enantioselective reaction;89%
1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

O-(4-cyanophenyl)hydroxylamine
94831-79-5

O-(4-cyanophenyl)hydroxylamine

C9H6F2N2O

C9H6F2N2O

Conditions
ConditionsYield
at 50℃; for 24h; Sealed tube; Acidic conditions;89%
N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester
100945-15-1

N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

N-benzyloxycarbonyl-2-amino-4,4-difluoro-2-butenoic acid methyl ester

N-benzyloxycarbonyl-2-amino-4,4-difluoro-2-butenoic acid methyl ester

Conditions
ConditionsYield
Stage #1: N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester With potassium tert-butylate In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: 1-ethoxy-2,2-difluoroethanol In tetrahydrofuran at 20℃; for 18h; Inert atmosphere;
87%
(R)-1-phenyl-ethyl-amine
3886-69-9

(R)-1-phenyl-ethyl-amine

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(αR)-N-(2,2-difluoroethylidene)(α-methylbenzyl)amine

(αR)-N-(2,2-difluoroethylidene)(α-methylbenzyl)amine

Conditions
ConditionsYield
In toluene at 100℃; for 3h;86%
1-trifluoromethoxybenzene
456-55-3

1-trifluoromethoxybenzene

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

1,1-difluoro-2,2-bis[p-(trifluoromethoxy)benzene]ethane
1314534-88-7

1,1-difluoro-2,2-bis[p-(trifluoromethoxy)benzene]ethane

Conditions
ConditionsYield
With boron trifluoride monohydrate In water at 0℃; for 1h; Friedel Crafts hydroxyalkylation;86%
1-(quinolin-4-yl)allyl acetate

1-(quinolin-4-yl)allyl acetate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(2S,3R)-1,1-difluoro-3-(quinolin-4-yl)pent-4-en-2-ol

(2S,3R)-1,1-difluoro-3-(quinolin-4-yl)pent-4-en-2-ol

Conditions
ConditionsYield
With C49H36Cl2IrN2O6P2; potassium carbonate In tetrahydrofuran; ethanol; isopropyl alcohol at 100℃; for 24h; Inert atmosphere; Sealed tube; Molecular sieve; enantioselective reaction;86%
4-chlorobenzylamine
104-86-9

4-chlorobenzylamine

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

C9H8ClF2N
906559-43-1

C9H8ClF2N

Conditions
ConditionsYield
In toluene at 0 - 100℃; for 2h;85%
4'-Methoxy-acetophenon-cyclohexylimin
41801-73-4

4'-Methoxy-acetophenon-cyclohexylimin

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

4,4-difluoro-3-hydroxy-1-(4-methoxyphenyl)-1-butanone

4,4-difluoro-3-hydroxy-1-(4-methoxyphenyl)-1-butanone

Conditions
ConditionsYield
In hexane Heating;84%
N-benzyl hydroxylalmine
622-30-0

N-benzyl hydroxylalmine

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

N-benzyl C-(difluoromethyl)nitrone

N-benzyl C-(difluoromethyl)nitrone

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 0.1h; Dean-Stark; Reflux;84%
With toluene-4-sulfonic acid In toluene for 0.5h; Reflux; Dean-Stark;
1-acetoxy-1-(4-bromophenyl)-2-propylene
1337953-40-8

1-acetoxy-1-(4-bromophenyl)-2-propylene

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(2S,3R)-3-(4-bromophenyl)-1,1-difluoropent-4-en-2-ol

(2S,3R)-3-(4-bromophenyl)-1,1-difluoropent-4-en-2-ol

Conditions
ConditionsYield
With C49H36Cl2IrN2O6P2; potassium carbonate In tetrahydrofuran; ethanol; isopropyl alcohol at 100℃; for 24h; Inert atmosphere; Sealed tube; Molecular sieve; enantioselective reaction;84%
1-Nitropropane
108-03-2

1-Nitropropane

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

1,1-difluoro-3-nitro-2-pentanol

1,1-difluoro-3-nitro-2-pentanol

Conditions
ConditionsYield
With 2,8,9-(i-Pr)3-2,5,8,9-tetraza-1-phosphabicyclo[3.3.3]undecen In tetrahydrofuran83%
With potassium carbonate In tetrahydrofuran Ambient temperature;68%
ethyl 3-nitropropanoate
3590-37-2

ethyl 3-nitropropanoate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

ethyl 5,5-difluoro-4-hydroxy-3-nitropentanoate

ethyl 5,5-difluoro-4-hydroxy-3-nitropentanoate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran Ambient temperature;82%
1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

3-acetoxy-3-(4-(trifluoromethyl)phenyl)-1-propene
169172-22-9

3-acetoxy-3-(4-(trifluoromethyl)phenyl)-1-propene

(2S,3R)-1,1-difluoro-3-(4-(trifluoromethyl)phenyl)pent-4-en-2-ol

(2S,3R)-1,1-difluoro-3-(4-(trifluoromethyl)phenyl)pent-4-en-2-ol

Conditions
ConditionsYield
With C49H36Cl2IrN2O6P2; potassium carbonate In tetrahydrofuran; ethanol; isopropyl alcohol at 100℃; for 24h; Inert atmosphere; Sealed tube; Molecular sieve; enantioselective reaction;82%
1'-acetoxyestragole
61691-82-5

1'-acetoxyestragole

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(2S,3R)-1,1-difluoro-3-(4-methoxyphenyl)pent-4-en-2-ol

(2S,3R)-1,1-difluoro-3-(4-methoxyphenyl)pent-4-en-2-ol

Conditions
ConditionsYield
With C49H36Cl2IrN2O6P2; potassium carbonate In tetrahydrofuran; ethanol; isopropyl alcohol at 100℃; for 24h; Inert atmosphere; Sealed tube; Molecular sieve; enantioselective reaction;82%
N-((1S)-1-phenylethyl)hydroxylamine
53933-47-4

N-((1S)-1-phenylethyl)hydroxylamine

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

N-(S)-(α-methylbenzyl)-C-(difluoromethyl)nitrone

N-(S)-(α-methylbenzyl)-C-(difluoromethyl)nitrone

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 0.5h; Reflux; Dean-Stark;80%
1-phenyl-2-propenyl acetate
7217-71-2

1-phenyl-2-propenyl acetate

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

(2S,3R)-1,1-difluoro-3-phenylpent-4-en-2-ol

(2S,3R)-1,1-difluoro-3-phenylpent-4-en-2-ol

Conditions
ConditionsYield
With C49H36Cl2IrN2O6P2; potassium carbonate In tetrahydrofuran; ethanol; isopropyl alcohol at 100℃; for 24h; Inert atmosphere; Sealed tube; Molecular sieve; enantioselective reaction;80%
nitromethane
75-52-5

nitromethane

1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

1,1-difluoro-3-nitro-2-propanol

1,1-difluoro-3-nitro-2-propanol

Conditions
ConditionsYield
With 2,8,9-(i-Pr)3-2,5,8,9-tetraza-1-phosphabicyclo[3,3,3]undecen In tetrahydrofuran79%
With potassium carbonate In tetrahydrofuran for 3h; Ambient temperature;65%
With sodium carbonate
With sodium carbonate at 20 - 60℃;
With sodium carbonate at 20 - 60℃;
1-ethoxy-2,2-difluoroethanol
148992-43-2

1-ethoxy-2,2-difluoroethanol

benzylamine
100-46-9

benzylamine

N-(2,2-difluoroethylidene)benzylamine
148628-63-1

N-(2,2-difluoroethylidene)benzylamine

Conditions
ConditionsYield
In toluene at 100℃; for 1h;78%
In toluene Reflux;
With toluene-4-sulfonic acid In toluene Reflux; Dean-Stark;

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