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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

(R)-4-(OXIRAN-2-YLMETHYL)ISOINDOLINE-1,3-DIONE

Cas:181140-34-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

(R)-N-(2,3-Epoxypropan-1-yl)phthalimide

Cas:181140-34-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(2R)-N-(Oxiranylmethyl)-phthalimide

Cas:181140-34-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Discount price CAS 181140-34-1 with competitive price

Cas:181140-34-1

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

(R)-N-Glycidylphthalimide CAS:181140-34-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organi

(R)-N-Glycidylphthalimide CAS:181140-34-1

Cas:181140-34-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-oxiranylmethyl]-

Cas:181140-34-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-oxiranylmethyl]-

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

(R)-(-)-GLYCIDYL PHTHALIMIDE CAS:181140-34-1

Cas:181140-34-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(R)-(-)-GLYCIDYL PHTHALIMIDE/High quality/Best price

Cas:181140-34-1

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(R)-4-(OXIRAN-2-YLMETHYL)ISOINDOLINE-1,3-DIONE

Cas:181140-34-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(R)-(-)-glycidylphthalimide

Cas:181140-34-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

(R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

(R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-oxiranylmethyl]-

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

(R)-(-)-GLYCIDYL PHTHALIMIDE cas no. 181140-34-1 98%

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(R)-2-(oxiran-2-ylMethyl)isoindoline-1,3-dione

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

(R)-(-)-N-(2,3-Epoxypropyl)phthalimide

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

(R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

(R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

(R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-oxiranylMethyl]-

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

(R)-(-)-Glycidyl phthalimide

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE Application:181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

181140-34-1 (R)-(-)-GLYCIDYL PHTHALIMIDE

Cas:181140-34-1

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

2-[(2R)-3-bromo-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
641617-21-2

2-[(2R)-3-bromo-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 18h; Product distribution / selectivity;90.6%
With sodium methylate In methanol; toluene at 20℃; for 1.5h; Product distribution / selectivity;56.7%
phthalimide
136918-14-4

phthalimide

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Stage #1: phthalimide; (R)-(-)-epichlorohydrin With benzyltrimethylammonium chloride In isopropyl alcohol at 40℃; for 24h;
Stage #2: With potassium tert-butylate In isopropyl alcohol at 20℃; for 3h;
89%
phthalimide
136918-14-4

phthalimide

(R)-oxiranemethanol
57044-25-4

(R)-oxiranemethanol

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20 - 25℃; for 18h;86%
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Mitsunobu reaction;75%
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran Mitsunobu reaction;
With di-tert-butyl-diazodicarboxylate; triphenylphosphine In dichloromethane at 20℃; Mitsunobu reaction;
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0 - 20℃; Molecular sieve;
phthalimide
136918-14-4

phthalimide

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

A

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

B

(R)-1-chloro-3-phtalimido-propan-2-ol

(R)-1-chloro-3-phtalimido-propan-2-ol

Conditions
ConditionsYield
With potassium fluoride on basic alumina In 2-methyltetrahydrofuran for 3h; Inert atmosphere; Reflux; stereospecific reaction;A 11%
B 85%
phthalimide
136918-14-4

phthalimide

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With benzyltrimethylammonium chloride; sodium carbonate In tert-butyl alcohol at 20℃; for 23h;84%
With benzyltrimethylammonium chloride In Isopropyl acetate at 20℃; for 72h;1.1 g
2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione
19667-37-9, 34839-11-7, 148857-42-5, 148857-44-7

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With potassium tert-butylate In isopropyl alcohol at 15℃; for 4h;75%
With potassium carbonate In toluene Reflux;n/a
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

potassium phtalimide
1074-82-4

potassium phtalimide

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With benzyltrimethylammonium chloride In tert-butyl alcohol at 20℃; for 24h;72%
(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

potassium phtalimide
1074-82-4

potassium phtalimide

A

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

B

(S)-N-glycidylphthalimide
161596-47-0

(S)-N-glycidylphthalimide

Conditions
ConditionsYield
With benzyltrimethylammonium chloride In DMF (N,N-dimethyl-formamide) at 20℃; for 16h;
phthalimide
136918-14-4

phthalimide

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: aluminum oxide / 1-methyl-pyrrolidin-2-one / 64 - 68 °C
1.2: 0.5 h
2.1: potassium carbonate / toluene / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum oxide / 1-methyl-pyrrolidin-2-one / 64 - 68 °C
1.2: 0.5 h
2.1: potassium carbonate / toluene / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum oxide / 1-methyl-pyrrolidin-2-one / 64 - 68 °C
1.2: 0.5 h
2.1: potassium carbonate / toluene / Reflux
View Scheme
phthalimide
136918-14-4

phthalimide

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

A

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione
19667-37-9, 34839-11-7, 148857-42-5, 148857-44-7

2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione

B

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With aluminum oxide In 1-methyl-pyrrolidin-2-one at 64 - 68℃;
2-oxiranylmethylisoindole-1,3-dione
5455-98-1

2-oxiranylmethylisoindole-1,3-dione

A

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

B

(S)-N-glycidylphthalimide
161596-47-0

(S)-N-glycidylphthalimide

Conditions
ConditionsYield
With Cu metal organic framework based on (R)-3,3′-bis(6-carboxy-2-naphthyl)-2,2′-dihydroxy-1,1′-binaphthyl*silica packed stainless steel column (10 cm long × 4.0 mm i.d.) In ethanol; hexane at 25℃; Resolution of racemate;
(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2R)-3-bromo-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
641617-21-2

2-[(2R)-3-bromo-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With hydrogen bromide In chloroform; water at 0℃; for 0.5h;96%
Stage #1: (-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione With iodobromomethane In 2-methyltetrahydrofuran at -78℃; for 0.0333333h;
Stage #2: With methyllithium In 2-methyltetrahydrofuran; diethyl ether at -78℃; for 1h; enantioselective reaction;
87%
(1R,2S)-1-Amino-2-indanol
136030-00-7

(1R,2S)-1-Amino-2-indanol

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2R)-2-hydroxy-3-[[(1R,2S)-2-hydroxyindan-1-yl]amino]propyl] isoindoline-1,3-dione
1309774-74-0

2-[(2R)-2-hydroxy-3-[[(1R,2S)-2-hydroxyindan-1-yl]amino]propyl] isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol at 0℃; for 9h; Reflux;93%
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2R)-2-hydroxy-3-[[(1S)-1-phenylethyl]amino]propyl]isoindoline-1,3-dione
1309774-76-2

2-[(2R)-2-hydroxy-3-[[(1S)-1-phenylethyl]amino]propyl]isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol at 0℃; for 9h; Reflux;91%
4-di[(2-hydroxyethyl)amino]-aniline
19298-14-7

4-di[(2-hydroxyethyl)amino]-aniline

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

C19H21N3O4

C19H21N3O4

Conditions
ConditionsYield
In ethanol at 75 - 85℃; for 24h;90%
(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

(R)-1-chloro-3-phtalimido-propan-2-ol

(R)-1-chloro-3-phtalimido-propan-2-ol

Conditions
ConditionsYield
Stage #1: (-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione With Chloroiodomethane In 2-methyltetrahydrofuran at -78℃; for 0.0333333h;
Stage #2: With methyllithium In 2-methyltetrahydrofuran; diethyl ether at -78℃; for 1h; enantioselective reaction;
90%
(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

C11H10INO3

C11H10INO3

Conditions
ConditionsYield
Stage #1: (-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione With diiodomethane In 2-methyltetrahydrofuran at -78℃; for 0.0333333h;
Stage #2: With methyllithium In 2-methyltetrahydrofuran; diethyl ether at -78℃; for 1h; enantioselective reaction;
89%
4-Chloroguaiacol
16766-30-6

4-Chloroguaiacol

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

(R)-1-(4-chloro-2-methoxyphenoxy)-3-phthalimido-2-propanol
874113-26-5

(R)-1-(4-chloro-2-methoxyphenoxy)-3-phthalimido-2-propanol

Conditions
ConditionsYield
With cesium fluoride In DMF (N,N-dimethyl-formamide) at 80℃; for 38h;87%
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 80℃; for 46h;59%
7-fluoro-1-(piperazin-1-yl)isoquinoline

7-fluoro-1-(piperazin-1-yl)isoquinoline

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2S)-3-[4-(7-fluoroisoquinolin-1-yl)piperazin-1-yl]-2-hydroxypropyl]-2,3-dihydro-1H-isoindole-1,3-dione

2-[(2S)-3-[4-(7-fluoroisoquinolin-1-yl)piperazin-1-yl]-2-hydroxypropyl]-2,3-dihydro-1H-isoindole-1,3-dione

Conditions
ConditionsYield
In acetonitrile at 70℃; for 6h;84%
1-(2-Methoxyphenyl)piperazine
35386-24-4

1-(2-Methoxyphenyl)piperazine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

(S)-(-)-1-phthaloylamino-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan-2-ol
180959-07-3

(S)-(-)-1-phthaloylamino-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan-2-ol

Conditions
ConditionsYield
In tetrahydrofuran for 72h; Heating;83%
(R)-Phenylglycinol
56613-80-0

(R)-Phenylglycinol

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2R)-2-hydroxy-3-[[(1R)-2-hydroxy-1-phenyl-ethyl]amino]propyl] isoindoline-1,3-dione
1309774-73-9

2-[(2R)-2-hydroxy-3-[[(1R)-2-hydroxy-1-phenyl-ethyl]amino]propyl] isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol at 0℃; for 9h; Reflux;83%
2-(2-(4-aminophenylamino)ethoxy)acetic acid

2-(2-(4-aminophenylamino)ethoxy)acetic acid

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

C21H23N3O6

C21H23N3O6

Conditions
ConditionsYield
In ethanol at 75 - 85℃; for 24h;80%
(S)-N-benzyl-α-cyclohexylethylamine
141396-54-5

(S)-N-benzyl-α-cyclohexylethylamine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2S)-2-hydroxy-3-[N-benzyl-[(1S)-α-cyclohexylethyl]amino]propyl]isoindoline-1,3-dione

2-[(2S)-2-hydroxy-3-[N-benzyl-[(1S)-α-cyclohexylethyl]amino]propyl]isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol for 13h; Cooling with ice; Reflux; regioselective reaction;77.66%
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2S)-2-hydroxy-3-[[(1S)-α-phenylethyl]amino]propyl]isoindoline-1,3-dione

2-[(2S)-2-hydroxy-3-[[(1S)-α-phenylethyl]amino]propyl]isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol for 13h; Cooling with ice; Reflux; regioselective reaction;76.69%
(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

(S)-2-(thiiran-2-ylmethyl)isoindoline-1,3-dione

(S)-2-(thiiran-2-ylmethyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With thiourea In methanol at 20℃; for 22h;74%
[(1S)-1-cyclohexylethyl]amine
17430-98-7

[(1S)-1-cyclohexylethyl]amine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2S)-2-hydroxy-3-[[(1S)-α-cyclohexylethyl]amino]propyl]isoindoline-1,3-dione

2-[(2S)-2-hydroxy-3-[[(1S)-α-cyclohexylethyl]amino]propyl]isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol for 13h; Cooling with ice; Reflux; regioselective reaction;73.07%
(2R)-2-aminobutan-1-ol
5856-63-3

(2R)-2-aminobutan-1-ol

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2R)-2-hydroxy-3-[[(1R)-1-(hydroxymethyl)propyl]amino]propyl] isoindoline-1,3-dione
1309774-75-1

2-[(2R)-2-hydroxy-3-[[(1R)-1-(hydroxymethyl)propyl]amino]propyl] isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol at 0℃; for 9h; Reflux;73%
carbon dioxide
124-38-9

carbon dioxide

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

C12H9NO5

C12H9NO5

Conditions
ConditionsYield
With C25H22OP(1+)*Br(1-) In chlorobenzene at 120℃; under 760.051 Torr; for 12h;73%
3,6-dibromo-9H-carbazole
6825-20-3

3,6-dibromo-9H-carbazole

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(S)-3-(3,6-dibromocarbazol-9-yl)-2-hydroxypropyl]isoindole-1,3-dione

2-[(S)-3-(3,6-dibromocarbazol-9-yl)-2-hydroxypropyl]isoindole-1,3-dione

Conditions
ConditionsYield
Stage #1: 3,6-dibromo-9H-carbazole With caesium carbonate In N,N-dimethyl-formamide at 30℃; for 1h;
Stage #2: (-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione In N,N-dimethyl-formamide at 30℃; for 15h;
72%
(S)-1-(1-Naphthyl)ethylamine
10420-89-0

(S)-1-(1-Naphthyl)ethylamine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2S)-2-hydroxy-3-[[(1S)-1-naphthylethyl]amino]propyl]isoindoline-1,3-dione

2-[(2S)-2-hydroxy-3-[[(1S)-1-naphthylethyl]amino]propyl]isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol for 13h; Cooling with ice; Reflux; regioselective reaction;72%
(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

(R)2-(oxiran-2-ylmethyl)isoindolin-1-one
1344708-81-1

(R)2-(oxiran-2-ylmethyl)isoindolin-1-one

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 25℃; Inert atmosphere;70%
(1R,2R)-N,N'-dibenzylcyclohexane-1,2-diamine
65838-10-0, 135613-88-6, 143443-23-6

(1R,2R)-N,N'-dibenzylcyclohexane-1,2-diamine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

N,N'-dibenzyl-N,N'-bis[(S)-2-hydroxy-3-phtalimido]-(1R,2R)-1,2-diaminocyclohexane

N,N'-dibenzyl-N,N'-bis[(S)-2-hydroxy-3-phtalimido]-(1R,2R)-1,2-diaminocyclohexane

Conditions
ConditionsYield
In isopropyl alcohol for 13h; Cooling with ice; Reflux; regioselective reaction;70%
[(1R)-1-cyclohexylethyl]amine
5913-13-3

[(1R)-1-cyclohexylethyl]amine

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

2-[(2S)-2-hydroxy-3-[[(1R)-α-cyclohexylethyl]amino]propyl]isoindoline-1,3-dione

2-[(2S)-2-hydroxy-3-[[(1R)-α-cyclohexylethyl]amino]propyl]isoindoline-1,3-dione

Conditions
ConditionsYield
In isopropyl alcohol for 13h; Cooling with ice; Reflux; regioselective reaction;68%
(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione
181140-34-1

(-)-2-[(2R)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione

4-(4-aminophenyl)morpholin-3-one
438056-69-0

4-(4-aminophenyl)morpholin-3-one

2,2'-((2R,2'R)-((4-(3-oxomorpholino)phenyl)azadiyl)bis(2-hydroxypropane-3,1-diyl))bis(isoindoline-1,3-dione)

2,2'-((2R,2'R)-((4-(3-oxomorpholino)phenyl)azadiyl)bis(2-hydroxypropane-3,1-diyl))bis(isoindoline-1,3-dione)

Conditions
ConditionsYield
In ethanol for 24h; Reflux;60%

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