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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(S)-(+)-Epichlorohydrin Manufacturer/High quality/Best price/In stock

Cas:67843-74-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality (S)-Epichlorohydrin supplier in China

Cas:67843-74-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 67843-74-7 (S)-(+)-epichlorohydrin

Cas:67843-74-7

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

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Wuhan Fortuna Chemical Co.,Ltd

High quality (S)-(+)-Epichlorohydrin Cas 67843-74-7 with good price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed a

High quality (S)-(+)-Epichlorohydrin Cas 67843-74-7 with good price

Cas:67843-74-7

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

(S)-(+)-Epichlorohydrin

Cas:67843-74-7

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (S)-1-chloro-2,3-epoxypropane

Cas:67843-74-7

Min.Order:1

Negotiable

Type:Other

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

(S)-(+)-Epichlorohydrin

Cas:67843-74-7

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

(S)-(+)-Epichlorohydrin CAS 67843-74-7 In stock 2-(Chloromethyl)oxirane

Cas:67843-74-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc. We are specialized in chemical synthesis, process development of pharm

(S)-(+)-Epichlorohydrin

Cas:67843-74-7

Min.Order:1 Kilogram

FOB Price: $25.0 / 30.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

(S)-(+)-Epichlorohydrin Basic information Product Name: (S)-(+)-Epichlorohydrin Synonyms: G-CHLOROPROPYLENE OXIDE;EPICHLORHYDRIN;EPICHLOROHYDRINE;CHLOROMETHYLOXIRANE;2,3-EPOXYPROPYL CHLO

(S)-(+)-Epichlorohydrin 67843-74-7

Cas:67843-74-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturing

(S)-(+)-Epichlorohydrin CAS:67843-74-7

Cas:67843-74-7

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 67843-74-7 with best quality

Cas:67843-74-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

S(+)-Epichlorohydrin

Cas:67843-74-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

(S)-(+)-Epichlorohydrin CAS67843-74-7

Cas:67843-74-7

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

Oxirane,2-(chloromethyl)-, (2S)-CAS NO.: 67843-74-7

Cas:67843-74-7

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white or off-white powder Storage:Store in sealed containers

High quality (S)-(+)-epichlorohydrin 67843-74-7 with best price

Cas:67843-74-7

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

ProName: (S)-(+)-Epichlorohydrin 67843-74-7 CasNo: 67843-74-7 Molecular Formula: C3H5ClO Appearance: white powder Application: Usd for medical intermediate DeliveryTime: PROMPT PackAge: IN 25kg drums Port: Shanghai po

(S)-(+)-Epichlorohydrin 67843-74-7

Cas:67843-74-7

Min.Order:100 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

(S)-(+)-Epichlorohydrin with CAS:67843-74-7

Cas:67843-74-7

Min.Order:1 Kilogram

FOB Price: $234.0 / 255.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

(S)-(+)-Epichlorohydrin CAS:67843-74-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

(S)-(+)-Epichlorohydrin CAS:67843-74-7

Cas:67843-74-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Oxirane,2-(chloromethyl)-, (2S)-

Cas:67843-74-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanxi Ankesi Biotechnology Co., Ltd

Our Advantage 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good qual

High purity 67843-74-7 (S)-(+)-epichlorohydrin with good price AKS

Cas:67843-74-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

(S)-(+)-Epichlorhydrin cas:67843-74-7

Cas:67843-74-7

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

(S)-(+)-Epichlorohydrin CAS:67843-74-7 Specification Item Specification Appearance Clear Colorless to Very Pale Yellow Liquid Assay 98%min Density 1.183 g/mL at 25 °C(lit.) Boiling Poi

Factory supply (S)-(+)-Epichlorohydrin

Cas:67843-74-7

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: (S)-(+)-Epichlorohydrin Synonyms: (S)-(+)-Epichlorohydrin 67843-74-7;(S)-epichlorohydrin 67843-74-7 (S)-(+)-Epichlorohydrin;(S)-(+)-2-(Chloromethyl)oxirane (S)-Epichlorohydrin (S) 1-Chloro-2,3-epoxypropane (S)-3-Chloropropylene Oxi

(S)-(+)-Epichlorohydrin big supplier with lower price

Cas:67843-74-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

(S)-(+)-epichlorohydrin

Cas:67843-74-7

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

S(+)-Epichlorohydrin

Cas:67843-74-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Tianjin Kind Pharma Co., Ltd.

Factory direct sales, accept customization. Kind Pharma has its own laboratory, we can do analytical testing for API (Active Pharmaceutical Ingredient), pharmaceutical intermediate, pesticide intermediate, additive and other chemical products, so it

(S)-(+)-Epichlorohydrin

Cas:67843-74-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(S)-(+)-EPICHLOROHYDRIN 67843-74-7

Cas:67843-74-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(S)-epichlorohydrin

Cas:67843-74-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(2S)-2-(chloromethyl)oxirane

Cas:67843-74-7

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1,3-Dichloro-2-propanol
96-23-1

1,3-Dichloro-2-propanol

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

Conditions
ConditionsYield
With halohydrin dehalogenase from Agrobacterium radiobacter AD1 (HheC mutant P175S/W249P) In aq. phosphate buffer pH=8; Concentration; Reagent/catalyst; Temperature; pH-value; Solvent; Enzymatic reaction; enantioselective reaction;93.7%
With halohydrin dehalogenase mutant HheCPS F86N In aq. phosphate buffer at 37℃; pH=8; Catalytic behavior; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;79.12%
1,2-Epoxy-3-bromopropane
3132-64-7

1,2-Epoxy-3-bromopropane

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(2R)-3-bromo-1,2-propanediol
14437-88-8

(2R)-3-bromo-1,2-propanediol

Conditions
ConditionsYield
With (R,R)-Jacobsen catalyst; water In tetrahydrofuran at 4℃; for 24h;A n/a
B 93%
O-benzyl carbamate
621-84-1

O-benzyl carbamate

epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

[(R)-3-chloro-2-hydroxypropyl]carbamic acid benzyl ester
641617-19-8

[(R)-3-chloro-2-hydroxypropyl]carbamic acid benzyl ester

Conditions
ConditionsYield
With air; 4-nitro-benzoic acid; (R,R)-((t-Bu)4-salen)Co(II) In various solvent(s) at 0℃; for 24h;A n/a
B 87%
(S)-3-chloro-2-hydroxypropyl-1-(toluene-4-sulfonate)
67800-61-7

(S)-3-chloro-2-hydroxypropyl-1-(toluene-4-sulfonate)

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

Conditions
ConditionsYield
With sodium ethane-1,2-diolate In ethylene glycol for 0.25h; Ambient temperature;85%
epichlorohydrin
106-89-8

epichlorohydrin

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

Conditions
ConditionsYield
With water; [(1-RR)-(Dibenzoyl-LTA)] at 5 - 20℃; for 7h; Product distribution / selectivity; Industry scale; Resolution of racemate;82%
With water; [(1-RR)-(Dibenzoyl-LTA)] at 5 - 20℃; for 3h; Product distribution / selectivity; Resolution of racemate;80%
With oligomeric (salen)Co(OSO2CF3); water at 20℃; for 15h;44%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

Conditions
ConditionsYield
With sodium hydroxide74%
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With C72H102Co2F12N4O12P2; water at 0 - 20℃; for 3h; optical yield given as %ee;A 45%
B 53%
With water; (S,S)-(salen)cobalt(III)(OAc) at 0℃; for 19h;A 46%
B 45%
With C114H155Co3N8O14Pol; water; acetic acid at 20℃; for 3h; Resolution of racemate; optical yield given as %ee; enantioselective reaction;A 46%
B n/a
(S)-1,3-dichloro-1-propanol

(S)-1,3-dichloro-1-propanol

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

Conditions
ConditionsYield
With potassium hydroxide In methanol Ambient temperature;51%
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

C

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With water; dimeric chiral (salen)Co complex linked with Al at 20℃; for 5h; Product distribution; Further Variations:; Catalysts;A 46%
B n/a
C n/a
With water; Cr(III)-endo,endo-2,5-diaminonorbornane-salen In tetrahydrofuran at 20℃; for 42h;A 46%
B n/a
C n/a
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate; water In dichloromethane; acetonitrile at 20℃; for 11h;A 45%
B n/a
C n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

3-monochloro-1,2-propanediol
96-24-2

3-monochloro-1,2-propanediol

Conditions
ConditionsYield
Stage #1: epichlorohydrin With C57H54CoN3O8 In dichloromethane at 20℃; for 0.25h;
Stage #2: With water In dichloromethane at 20℃; for 12h; Cooling with ice; enantioselective reaction;
A 46%
B n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

C

1,3-Dichloro-2-propanol
96-23-1

1,3-Dichloro-2-propanol

Conditions
ConditionsYield
With hydrogenchloride; tert-butyl methyl ether; dimeric chiral (salen)Co complex linked with Al In diethyl ether at 0 - 5℃; for 2h; Product distribution; Further Variations:; Catalysts;A n/a
B n/a
C 45%
Methyl 4-hydroxyphenylacetate
14199-15-6

Methyl 4-hydroxyphenylacetate

epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

methyl (R)-2-(4-(3-chloro-2-hydroxypropoxy)phenyl)acetate
724776-52-7

methyl (R)-2-(4-(3-chloro-2-hydroxypropoxy)phenyl)acetate

Conditions
ConditionsYield
With (R,R)-Jacobsen(III)- catalyst immobilized by sulfonic acid functionalized SBA-16 mesoporous silica In tetrahydrofuran at 20℃; for 12h; optical yield given as %ee; enantioselective reaction;A 44%
B n/a
epichlorohydrin
106-89-8

epichlorohydrin

phenol
108-95-2

phenol

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-1-chloro-3-phenoxy-2-propanol
140630-45-1

(R)-1-chloro-3-phenoxy-2-propanol

Conditions
ConditionsYield
With (R,R)-Jacobsen(III)- catalyst immobilized by sulfonic acid functionalized SBA-16 mesoporous silica In tetrahydrofuran at 20℃; for 12h; optical yield given as %ee; enantioselective reaction;A 43%
B n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

C

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With (S,S)-[N,N-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane-diamino]cobalt(III) acetate; (salen)Co(III)-AlCl3; water In tetrahydrofuran at 19.84℃; for 3h; Kinetics; Reagent/catalyst; Solvent; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 41%
With C8F17COOH; water; (R,R)-Co(III)(salen) In toluene at 20℃; for 15h;A n/a
B n/a
C 40%
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate; water In dichloromethane; acetonitrile at 0 - 20℃; for 1.5h;A n/a
B n/a
C 40%
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

Conditions
ConditionsYield
With Agromyces mediolanus ZJB120203 epoxide hydrolase Resolution of racemate; enantioselective reaction;A 21.5%
B n/a
enantiomeric resolution by complexation gas chromatography on nickel(II)bis<(1R)-3-(heptafluorobutyryl)camphorate>;
With water; C6H15N*C44H61CoN2O10 at 5 - 20℃; for 3 - 9h; Product distribution / selectivity; Resolution of racemate;
1,3-Dichloro-2-propanol
96-23-1

1,3-Dichloro-2-propanol

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

Conditions
ConditionsYield
With potassium carbonate; Co(II)(3,5-Cl,Cl-sal)2(S-CHXDA) (e.e. 1.) 130-150 deg C, 3 hr in vacuo; 2.) CH2Cl2, 25 deg C, 6 days; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
With potassium carbonate In dichloromethane at 25℃; Product distribution; Mechanism; study of asymmetric cyclization using different optically active cobalt (salen) or nickel (salen) type complexes;
With potassium phosphate; [(R,R)-(salen)Co(II)]2*Al(NO3)3 In tetrahydrofuran at 20℃; for 3h;
(S)-3-chloro-2-hydroxypropyl-1-(toluene-4-sulfonate)
67800-61-7

(S)-3-chloro-2-hydroxypropyl-1-(toluene-4-sulfonate)

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

Conditions
ConditionsYield
With sodium 2-hydroxyethoxide In ethylene glycol for 0.0833333h; Title compound not separated from byproducts;
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

C

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

D

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With water; poly(Co(III)(OTs)-salen-norbornene) In chlorobenzene at 20℃; for 0.5h; Product distribution; Further Variations:; Catalysts; reaction times;
Co(Salen)/SBA-16-C8 In tetrahydrofuran; water at 24.84℃; for 20h;
With C118H146Co2N4O14S2; water In acetonitrile at 20℃; optical yield given as %ee; enantioselective reaction;
(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

Conditions
ConditionsYield
With sodium citrate buffer; Agrobacterium radiobacter AD1 haloalcohol dehalogenase; sodium chloride at 22℃; pH=5.5; Product distribution; Further Variations:; pH-values;
With Agrobacterium radiobacter halohydrin dehalogenase; sodium chloride for 1h; pH=7.5; Tris-SO4 buffer; Enzymatic reaction;
tert-butyl carbamate
4248-19-5

tert-butyl carbamate

epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-3-chloro-2-hydroxypropylcarbamic acid tert-butyl ester
1072792-33-6

(R)-3-chloro-2-hydroxypropylcarbamic acid tert-butyl ester

Conditions
ConditionsYield
With (1R,2R)-(-)-N,N'-bis(3,5-di-tert-butylsalicydene)-1,2-cyclohexanediaminocobalt(II); 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; 4-nitro-benzoic acid at 20℃; for 8h; optical yield given as %ee; enantioselective reaction;
Stage #1: tert-butyl carbazate With chiral Co(III) polymeric salen complex In dichloromethane for 0.166667h;
Stage #2: epichlorohydrin In dichloromethane for 20h; enantioselective reaction;
A n/a
B n/a
(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With (R,R)-Jacobsen catalyst; waterA n/a
B n/a
aniline
62-53-3

aniline

epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

C

(S)-(+)-1-chloro-3-(phenylamino)-propan-2-ol
195455-97-1

(S)-(+)-1-chloro-3-(phenylamino)-propan-2-ol

D

(R)-(+)-N-(3-chloro-2-hydroxypropyl)aniline
195455-98-2

(R)-(+)-N-(3-chloro-2-hydroxypropyl)aniline

Conditions
ConditionsYield
Stage #1: epichlorohydrin With C65H56CoN3O8 In dichloromethane at 27 - 28℃; for 0.166667h;
Stage #2: aniline In dichloromethane at 27 - 28℃; enantioselective reaction;
A n/a
B n/a
C n/a
D n/a
potassium cyanate
590-28-3

potassium cyanate

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

(5S)-5-(chloromethyl)-1,3-oxazolidin-2-one
169048-83-3

(5S)-5-(chloromethyl)-1,3-oxazolidin-2-one

Conditions
ConditionsYield
In water for 15h; Heating;100%
With water for 15h; Reflux;60%
With magnesium sulfate In water at 100℃; for 5h;41%
In water Reflux;
In water for 19h; Reflux;
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

2-benzylamino-N-(4-benzyloxyphenyl)acetamide
777934-39-1

2-benzylamino-N-(4-benzyloxyphenyl)acetamide

2-{benzyl[(2S)-3-chloro-2-hydroxypropyl]amino}-N-(4-benzyloxyphenyl)acetamide
777934-41-5

2-{benzyl[(2S)-3-chloro-2-hydroxypropyl]amino}-N-(4-benzyloxyphenyl)acetamide

Conditions
ConditionsYield
With magnesium sulfate In methanol; dichloromethane at 35℃; for 72h;100%
With magnesium sulfate In methanol; dichloromethane at 35℃; for 72h;
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

2-chloro-ethanol
107-07-3

2-chloro-ethanol

(S)-1-(2-chloroethoxy)-3-chloropropan-2-ol
861852-07-5

(S)-1-(2-chloroethoxy)-3-chloropropan-2-ol

Conditions
ConditionsYield
With boron trifluoride diethyl etherate at 45℃; for 1.5h;100%
With boron trifluoride diethyl etherate at 45℃; for 1.5h;96%
With boron trifluoride diethyl etherate In toluene at 36 - 38℃; Large scale reaction;
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

bromopentene
1119-51-3

bromopentene

(2S)-1-chlorooct-7-en-2-ol
850715-25-2

(2S)-1-chlorooct-7-en-2-ol

Conditions
ConditionsYield
Stage #1: bromopentene With magnesium In tetrahydrofuran for 0.5h; Heating;
Stage #2: (S)-epichlorohydrin In tetrahydrofuran at -50 - 20℃; for 2h;
100%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

1-bromo-2,4,5-trifluorobenzene
327-52-6

1-bromo-2,4,5-trifluorobenzene

(S)-1-chloro-3-(2,4,5-trifluorophenyl)propan-2-ol
1246960-15-5

(S)-1-chloro-3-(2,4,5-trifluorophenyl)propan-2-ol

Conditions
ConditionsYield
Stage #1: 1-bromo-2,4,5-trifluorobenzene With isopropylmagnesium chloride In tetrahydrofuran at -20 - 3℃; for 1.16667h; Inert atmosphere;
Stage #2: With copper(l) iodide In tetrahydrofuran at -10℃; for 0.5h; Inert atmosphere;
Stage #3: (S)-epichlorohydrin In tetrahydrofuran at -10 - 0℃; for 2.5h; Inert atmosphere;
100%
Stage #1: 1-bromo-2,4,5-trifluorobenzene With magnesium; 1,2-dibromomethane In tetrahydrofuran at 20℃;
Stage #2: (S)-epichlorohydrin With copper(l) iodide In tetrahydrofuran at 0 - 20℃; for 2.5h; Product distribution / selectivity;
Stage #1: 1-bromo-2,4,5-trifluorobenzene With magnesium; ethylene dibromide In tetrahydrofuran at 20℃;
Stage #2: (S)-epichlorohydrin; copper(l) iodide In tetrahydrofuran at 0 - 20℃; for 2.5h; Product distribution / selectivity;
Stage #1: 1-bromo-2,4,5-trifluorobenzene With isopropylmagnesium chloride In tetrahydrofuran at 0 - 22℃; for 4h;
Stage #2: (S)-epichlorohydrin With copper(l) chloride In tetrahydrofuran at 25 - 40℃; for 5h;
Stage #3: With acetic acid In tetrahydrofuran; tert-butyl methyl ether
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

3,4-dichloro-benzeneacetonitrile
3218-49-3

3,4-dichloro-benzeneacetonitrile

((1S,2R)-2-(aminomethyl)-2-(3,4-dichlorophenyl)cyclopropyl)methanol
910028-19-2

((1S,2R)-2-(aminomethyl)-2-(3,4-dichlorophenyl)cyclopropyl)methanol

Conditions
ConditionsYield
Stage #1: (S)-epichlorohydrin; 3,4-dichloro-benzeneacetonitrile With sodium hexamethyldisilazane In tetrahydrofuran at -15 - 4℃; Inert atmosphere;
Stage #2: With dimethylsulfide borane complex at -5 - 40℃; for 6.5h;
100%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

isopropenylmagnesium bromide
13291-18-4

isopropenylmagnesium bromide

(S)-(2-methylallyl)oxirane

(S)-(2-methylallyl)oxirane

Conditions
ConditionsYield
Stage #1: isopropenylmagnesium bromide With copper(l) iodide; boron trifluoride diethyl etherate In tetrahydrofuran at -78 - -30℃; for 0.5h; Inert atmosphere;
Stage #2: (S)-epichlorohydrin In tetrahydrofuran at -30℃; for 0.5h; Inert atmosphere;
Stage #3: With sodium hydroxide In dichloromethane at 35℃; for 30h; Inert atmosphere;
99%
Stage #1: isopropenylmagnesium bromide With copper(l) iodide In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: (S)-epichlorohydrin In tetrahydrofuran at -30℃; for 0.5h; Inert atmosphere;
Stage #3: With sodium hydroxide In dichloromethane at 35℃; for 30h; Inert atmosphere;
10.29 g
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

dibenzylamine
103-49-1

dibenzylamine

(S)-N,N-dibenzylamino-1-(oxiran-2-ylmethyl)methylamine
565176-84-3

(S)-N,N-dibenzylamino-1-(oxiran-2-ylmethyl)methylamine

Conditions
ConditionsYield
Stage #1: (S)-epichlorohydrin; dibenzylamine In isopropyl alcohol at 0 - 20℃;
Stage #2: With potassium hydroxide In isopropyl alcohol at 0℃;
98.5%
With sodium hydroxide at 65 - 70℃; for 24h;95%
In isopropyl alcohol at 0℃; for 24h;91.5%
Stage #1: (S)-epichlorohydrin; dibenzylamine In methanol at 20℃; for 48h;
Stage #2: With potassium hydroxide In water; tert-butyl alcohol at 20℃; for 48h;
45.8%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

1-butynyllithium
1119-18-2

1-butynyllithium

(S)-1-chlorohept-4-yn-2-ol
1026660-51-4

(S)-1-chlorohept-4-yn-2-ol

Conditions
ConditionsYield
With boron trifluoride diethyl etherate98%
ortho-mercaptophenol
1121-24-0

ortho-mercaptophenol

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

(R)-3-[(2-hydroxyphenyl)thio]-1,2-epoxypropane
1588421-61-7

(R)-3-[(2-hydroxyphenyl)thio]-1,2-epoxypropane

Conditions
ConditionsYield
With pyridine In water at 20℃; for 24h; enantiospecific reaction;98%
Stage #1: ortho-mercaptophenol With pyridine In N,N-dimethyl-formamide at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: (S)-epichlorohydrin In N,N-dimethyl-formamide at 140℃; for 0.166667h; Inert atmosphere; Microwave irradiation;
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

N-[4-(3-morpholinon-4-yl)phenyl]-2-thiophene chloride

N-[4-(3-morpholinon-4-yl)phenyl]-2-thiophene chloride

(S)-N-(2,3-epoxy-1-propyl)-N-[4-(3-morpholinon-4-yl)phenyl]-2-thiophenecarboxamide

(S)-N-(2,3-epoxy-1-propyl)-N-[4-(3-morpholinon-4-yl)phenyl]-2-thiophenecarboxamide

Conditions
ConditionsYield
Stage #1: N-[4-(3-morpholinon-4-yl)phenyl]-2-thiophene chloride With lithium tert-butoxide In tetrahydrofuran at 20℃; for 0.333333h;
Stage #2: (S)-epichlorohydrin at 50 - 60℃; for 3h;
98%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

dibenzylamine
103-49-1

dibenzylamine

(S)-3-chloro-2-hydroxypropyl dibenzylamine
1236384-02-3

(S)-3-chloro-2-hydroxypropyl dibenzylamine

Conditions
ConditionsYield
With calcium chloride at 33℃; under 608.041 - 912.061 Torr; for 8h; Product distribution / selectivity;97%
With calcium chloride In dichloromethane at 33℃; for 8h; Product distribution / selectivity;97%
In dichloromethane at 25℃; for 20h; Solvent; Temperature;95.16%
In ethanol for 6h; Reflux;28.3 g
at 25 - 30℃; for 18h;
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

(S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne
148516-13-6

(S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne

Conditions
ConditionsYield
Stage #1: trimethylsilylacetylene With n-butyllithium In tetrahydrofuran; hexane at -60℃; for 0.5h;
Stage #2: (S)-epichlorohydrin With boron trifluoride diethyl etherate In tetrahydrofuran; hexane at -60℃; for 2h;
96%
With n-butyllithium; boron trifluoride diethyl etherate In tetrahydrofuran; hexane at -60℃; for 2h;96%
With n-butyllithium; boron trifluoride diethyl etherate 1.) THF, -78 deg C, 25 min, 2.) THF, -30 deg C, 18 h; Multistep reaction;
methanol
67-56-1

methanol

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

carbon monoxide
201230-82-2

carbon monoxide

methyl (S)-4-chloro-3-hydroxybutanoate
86728-93-0

methyl (S)-4-chloro-3-hydroxybutanoate

Conditions
ConditionsYield
With 3-HYDROXYPYRIDINE; dicobalt octacarbonyl In tetrahydrofuran at 55℃; under 31028.9 Torr; for 9h;96%
4-aminopyridine; dicobalt octacarbonyl In tert-butyl alcohol at 40℃; under 7500.75 Torr; for 5h; Product distribution / selectivity;92%
4-aminopyridine; dicobalt octacarbonyl at 33℃; under 7500.75 Torr; for 25h; Product distribution / selectivity;85%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

N-(2,6-dimethylphenyl)-2-(piperazin-1-yl)acetamide
5294-61-1

N-(2,6-dimethylphenyl)-2-(piperazin-1-yl)acetamide

(S)-2-(4-(3-chloro-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
1427177-25-0

(S)-2-(4-(3-chloro-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide

Conditions
ConditionsYield
In water at 15℃; for 1h;96%
(R)-2-hydroxy-2'-(methoxymethoxy)-1,1'-binaphthalene

(R)-2-hydroxy-2'-(methoxymethoxy)-1,1'-binaphthalene

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

2-[(S)-glycidyloxy]-2'-(methoxymethyloxy)-1,1'-binaphthalene

2-[(S)-glycidyloxy]-2'-(methoxymethyloxy)-1,1'-binaphthalene

Conditions
ConditionsYield
Stage #1: (R)-2-hydroxy-2'-(methoxymethoxy)-1,1'-binaphthalene With tetrabutylammomium bromide; potassium hydroxide In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: (S)-epichlorohydrin In tetrahydrofuran at 20℃; for 20h;
96%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

N-[4-(3-morpholinon-4-yl)phenyl]-5-chloro-2-thiophenecarboxamide

N-[4-(3-morpholinon-4-yl)phenyl]-5-chloro-2-thiophenecarboxamide

(S)-N-(2,3-epoxy-1-propyl)-N-[4-(3-morpholinon-4-yl)phenyl]-5-chloro-2-thiophenecarboxamide

(S)-N-(2,3-epoxy-1-propyl)-N-[4-(3-morpholinon-4-yl)phenyl]-5-chloro-2-thiophenecarboxamide

Conditions
ConditionsYield
Stage #1: N-[4-(3-morpholinon-4-yl)phenyl]-5-chloro-2-thiophenecarboxamide With lithium tert-butoxide In tetrahydrofuran at 20℃; for 0.333333h;
Stage #2: (S)-epichlorohydrin at 50 - 60℃; for 3h;
96%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

(S)-(-)-1-bromo-3-chloro-2-propanol

(S)-(-)-1-bromo-3-chloro-2-propanol

Conditions
ConditionsYield
With dilithium tetrabromonickelate(II) In tetrahydrofuran 1) 0 degC, 2 h, 2) r.t., 1 h;95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

tert-butyldimethylsilyl cyanide
56522-24-8

tert-butyldimethylsilyl cyanide

(3S)-3-[(tert-butyldimethylsilyl)oxy]-4-chlorobutanenitrile
884902-55-0

(3S)-3-[(tert-butyldimethylsilyl)oxy]-4-chlorobutanenitrile

Conditions
ConditionsYield
With potassium cyanide; 18-crown-6 ether95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

6-(4-bromophenyl)-1,2,3,4-tetrahydro-1,5-naphthyridine
791856-68-3

6-(4-bromophenyl)-1,2,3,4-tetrahydro-1,5-naphthyridine

(+)-(S)-6-(4-bromophenyl)-1-(3-chloro-2-hydroxypropyl)-1,2,3,4-tetrahydro-1,5-naphthyridine
944152-87-8

(+)-(S)-6-(4-bromophenyl)-1-(3-chloro-2-hydroxypropyl)-1,2,3,4-tetrahydro-1,5-naphthyridine

Conditions
ConditionsYield
With ytterbium(III) triflate In dichloromethane at 60℃; for 5h;95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

butyric acid
107-92-6

butyric acid

butyric acid-3-chloro-(S)-2-hydroxy-propyl ester
890051-54-4

butyric acid-3-chloro-(S)-2-hydroxy-propyl ester

Conditions
ConditionsYield
With chromium chloride at 60℃; for 24h;95%
Stage #1: butyric acid With N,N'-bis(3,5-di-tert-butylsalicylidene)ethylenediaminocobalt(II); oxygen at 50℃; for 1h;
Stage #2: (S)-epichlorohydrin With diisopropylamine at 20℃; for 24h;
82.0 %Chromat.
n-butyl magnesium bromide
693-03-8

n-butyl magnesium bromide

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

(S)-1-chlorohept-6-en-2-ol
1224174-07-5

(S)-1-chlorohept-6-en-2-ol

Conditions
ConditionsYield
With copper(l) iodide In tetrahydrofuran at -78℃;95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

tert-butyl 4-[[(2S)-oxiran-2-yl]methyl]piperazine-1-carboxylate
335165-58-7

tert-butyl 4-[[(2S)-oxiran-2-yl]methyl]piperazine-1-carboxylate

Conditions
ConditionsYield
In ethanol for 12h;95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

benzyl alcohol
100-51-6

benzyl alcohol

Conditions
ConditionsYield
Stage #1: (S)-epichlorohydrin With tetrabutylammomium bromide; sodium hydroxide In water at 20℃;
Stage #2: benzyl alcohol In water at 20℃; regioselective reaction;
95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

4-bromo-1,1'-biphenyl
92-66-0

4-bromo-1,1'-biphenyl

(S)-1-([1,1’-biphenyl]-4-yl)-3-chloropropan-2-ol
1573000-28-8

(S)-1-([1,1’-biphenyl]-4-yl)-3-chloropropan-2-ol

Conditions
ConditionsYield
Stage #1: 4-bromo-1,1'-biphenyl With iodine; magnesium In tetrahydrofuran at 40 - 50℃; for 2h;
Stage #2: (S)-epichlorohydrin With copper(l) iodide In tetrahydrofuran at -15 - 5℃; for 2h;
95%
Stage #1: 4-bromo-1,1'-biphenyl With iodine; magnesium In tetrahydrofuran at 45 - 50℃; for 0.166667h;
Stage #2: With copper(l) iodide In tetrahydrofuran at -10 - 5℃; for 0.5h;
Stage #3: (S)-epichlorohydrin In tetrahydrofuran for 4h;
92%
Stage #1: 4-bromo-1,1'-biphenyl With n-butyllithium In tetrahydrofuran; hexane at -78 - -10℃; for 2.5h; Inert atmosphere;
Stage #2: (S)-epichlorohydrin In tetrahydrofuran; hexane at 20℃; for 5h;
85%
Stage #1: 4-bromo-1,1'-biphenyl With iodine; magnesium In tetrahydrofuran at 45 - 50℃; Inert atmosphere; Industrial scale;
Stage #2: With copper(l) iodide In tetrahydrofuran at -20 - -15℃; for 0.5h; Industrial scale;
Stage #3: (S)-epichlorohydrin Reagent/catalyst; Temperature; Industrial scale; Further stages;
48.7 kg
Stage #1: 4-bromo-1,1'-biphenyl With iodine; magnesium In tetrahydrofuran at 35 - 45℃; Inert atmosphere;
Stage #2: (S)-epichlorohydrin With copper(l) iodide In tetrahydrofuran at -20 - -15℃; Inert atmosphere;
45.4 g
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

triphenylmethanethiol
3695-77-0

triphenylmethanethiol

(S)-1-chloro-3-(tritylthio)propan-2-ol

(S)-1-chloro-3-(tritylthio)propan-2-ol

Conditions
ConditionsYield
With potassium fluoride In methanol at 20℃; for 72h;95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

n-Butyl chloride
109-69-3

n-Butyl chloride

(S)-1-chloroheptane-2-ol
81007-64-9

(S)-1-chloroheptane-2-ol

Conditions
ConditionsYield
Stage #1: n-Butyl chloride With iodine; magnesium In tetrahydrofuran at 80℃; for 1h; Inert atmosphere;
Stage #2: (S)-epichlorohydrin With copper(l) cyanide In tetrahydrofuran at -78 - -20℃; for 3h; Inert atmosphere;
95%
4-phenyl-1-piperazine
92-54-6

4-phenyl-1-piperazine

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

C13H18N2O

C13H18N2O

Conditions
ConditionsYield
With sodium hydroxide In water at 75℃; for 0.25h;95%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

tris-iso-propylsilyl acetylene
89343-06-6

tris-iso-propylsilyl acetylene

(2S)-1-chloro-5-(triisopropylsilanyl)pent-4-yn-2-ol
638222-25-0

(2S)-1-chloro-5-(triisopropylsilanyl)pent-4-yn-2-ol

Conditions
ConditionsYield
Stage #1: tris-iso-propylsilyl acetylene With n-butyllithium; boron trifluoride-tetrahydrofuran complex In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: (S)-epichlorohydrin In tetrahydrofuran; hexane at -78℃; for 2h; Hiroa reaction;
94%
ethyl bromide
74-96-4

ethyl bromide

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

S-1-chloromethyl-1-butanol
141339-40-4

S-1-chloromethyl-1-butanol

Conditions
ConditionsYield
Stage #1: ethyl bromide With iodine; magnesium In diethyl ether for 1.5h; Reflux;
Stage #2: (S)-epichlorohydrin With copper(l) cyanide In tetrahydrofuran; diethyl ether at -78 - -20℃; for 3h;
Stage #3: With ammonium chloride In tetrahydrofuran; diethyl ether; water
94%
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