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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

(R)-(-)-3-Chloro-1,2-propanediol Manufacturer/High quality/Best price/In stock

Cas:57090-45-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product Description

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:1 Kilogram

FOB Price: $5.0 / 30.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (R)-3-chloropropane-1,2-diol

Cas:57090-45-6

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

(R)-(-)-3-Chloro-1,2-propanediol Basic information Product Name: (R)-(-)-3-Chloro-1,2-propanediol Synonyms: (2R)-3-CHLOROPROPANE-1,2-DIOL;GLYCEROL (R)-(-)-ALPHA-MONOCHLOROHYDRIN;(R)-GLYC

(R)-(-)-3-Chloro-1,2-propanediol 57090-45-6

Cas:57090-45-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

(R)-(-)-3-Chloro-1,2-propanediol CAS :57090-45-6

Cas:57090-45-6

Min.Order:1 Kilogram

FOB Price: $7800.0 / 8000.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 57090-45-6 with best quality

Cas:57090-45-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

R(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

(R)-(-)-3-Chloro-1,2-propanediol CAS57090-45-6

Cas:57090-45-6

Min.Order:1 Kilogram

FOB Price: $5.0 / 9.0

Type:Trading Company

inquiry

Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best serv

99% (R)-(-)-3-Chloro-1,2-propanediol Manufacturer 57090-45-6

Cas:57090-45-6

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,2-Propanediol,3-chloro-, (2R)- 57090-45-6

Cas:57090-45-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

(R)-(-)-3-Chloro-1,2-propanediol Basic information Product Name: (R)-(-)-3-Chloro-1,2-propanediol Synonyms: (R)-3-Chloro-1,2-propanediol, 95+%;R - 3 - chloro - 1, 2 - propylene glycol;(R)-(-)-3-Chloro-1,2-propanediol;(2R)-3-chloro-1,2-propanedi

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Chemical Intermediate, (R)-(-)-3-Chloro-1,2-propanediol CAS:57090-45-6

Cas:57090-45-6

Min.Order:1 Kilogram

FOB Price: $20.0 / 24.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

(R)-(-)-3-Chloro-1,2-propanediol CAS:57090-45-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

(R)-(-)-3-Chloro-1,2-propanediol CAS:57090-45-6

Cas:57090-45-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,2-Propanediol,3-chloro-, (2R)-

Cas:57090-45-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

(R)-3-Chloro-1,2-propanediol cas:57090-45-6

Cas:57090-45-6

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

(R)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:1 Kilogram

FOB Price: $10.0 / 30.0

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white crystalline powder and Yellowish to yellow liquid Storage: keep in dry and cool place Package:As customer request Application:Used for research and industrial manufacture.Food/Medicine/Industria grade Transporta

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

(R)-(-)-3-Chloro-1,2-propanediol CAS 57090-45-6

Cas:57090-45-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

R(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

(R)-(-)-3-CHLORO-1,2-PROPANEDIOL 57090-45-6

Cas:57090-45-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

(R)-(-)-3-Chloro-1,2-propanediol/High quality/Best price

Cas:57090-45-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality (R)-(-)-3-Chloro-1,2-Propanediol

Cas:57090-45-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

(R)-(-)-3-Chloro-1,2-propanediol

Cas:57090-45-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: (R)-3-Chloro-1,2-Propanediol CAS No.: 57090-45-6 Molecule Formula:C3H7ClO2 Molecule Weight:110.54 Purity: 98.0% Package: 200kg/drum Description:Light yellow to colorless liquid Manufacture Standards:Enterprise Standard

Lower Price (R)-3-Chloro-1,2-Propanediol on stock

Cas:57090-45-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(R)-(-)-3-Chloro-1,2-propanediol Manufacturer/High quality/Best price/In stock

Cas:57090-45-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

(R)-(-)-3-Chloro-1,2-propanediol 57090-45-6CAS NO.: 57090-45-6

Cas:57090-45-6

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Synthetic route

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With (R)-2-chloropropionic acid In water at 80 - 90℃; for 15h; Reagent/catalyst; Temperature;95.57%
With (R,R)-Jacobsen catalyst; water In tetrahydrofuran at 4℃; for 24h;41%
Stage #1: With N,N'-bis(3,5-di-tert-butylsalicylidene)ethylenediaminocobalt(II); camphor-10-sulfonic acid; oxygen In tetrahydrofuran for 1h;
Stage #2: (R)-(-)-epichlorohydrin With water In tetrahydrofuran at 20℃; for 20h;
93.7 %Chromat.
(R)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane
57044-24-3

(R)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With hydrogenchloride86%
[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methanamine
82954-65-2

[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methanamine

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With hydrogenchloride; sodium chloride; sodium nitrite In water at 10 - 20℃; for 24h; Substitution;82%
(1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one
95589-30-3

(1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanolA 55%
B n/a
C n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With C72H102Co2F12N4O12P2; water at 0 - 20℃; for 3h; optical yield given as %ee;A 45%
B 53%
With water; (S,S)-(salen)cobalt(III)(OAc) at 0℃; for 19h;A 46%
B 45%
With C114H155Co3N8O14Pol; water; acetic acid at 20℃; for 3h; Resolution of racemate; optical yield given as %ee; enantioselective reaction;A 46%
B n/a
epichlorohydrin
106-89-8

epichlorohydrin

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With water In tetrahydrofuran at 4℃; for 24h;50%
In tetrahydrofuran; water
In tetrahydrofuran; water
With Co(salen) macrocycles 1(OTs) at 20℃; for 0.333333h; optical yield given as %ee; enantioselective reaction;
2,3-Dichloro-1-propanol
616-23-9

2,3-Dichloro-1-propanol

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

C

(S)-1,3-dichloro-1-propanol

(S)-1,3-dichloro-1-propanol

D

epichlorohydrin
106-89-8

epichlorohydrin

Conditions
ConditionsYield
With epoxide hydrolase from Agrobacterium radiobacter AD1; halohydrin dehalogenase from Agrobacterium radiobacter AD1; Tris-SO4 buffer In water at 30℃; for 20h; pH=7.5; kinetic resolution; Further byproducts given;A n/a
B n/a
C 49.5%
D n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

C

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With water; dimeric chiral (salen)Co complex linked with Al at 20℃; for 5h; Product distribution; Further Variations:; Catalysts;A 46%
B n/a
C n/a
With water; Cr(III)-endo,endo-2,5-diaminonorbornane-salen In tetrahydrofuran at 20℃; for 42h;A 46%
B n/a
C n/a
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate; water In dichloromethane; acetonitrile at 20℃; for 11h;A 45%
B n/a
C n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With water at 20℃; for 8h; optical yield given as %ee;A 45%
B n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

C

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With (S,S)-[N,N-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane-diamino]cobalt(III) acetate; water In tetrahydrofuran at 0 - 20℃;A 43%
B n/a
C n/a
With (S,S)-(salen)Co(III)-OTs; water at 0 - 4℃; for 16h;A 42.3%
B n/a
C n/a
With poly-salen-Co(III); water In tetrahydrofuran at 10℃; for 12h;
With (S,S)-[N,N-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane-diamino]cobalt(III) acetate; water In tetrahydrofuran at 0 - 20℃; Title compound not separated from byproducts;
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

C

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With (S,S)-[N,N-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane-diamino]cobalt(III) acetate; (salen)Co(III)-AlCl3; water In tetrahydrofuran at 19.84℃; for 3h; Kinetics; Reagent/catalyst; Solvent; optical yield given as %ee; enantioselective reaction;A n/a
B n/a
C 41%
With C8F17COOH; water; (R,R)-Co(III)(salen) In toluene at 20℃; for 15h;A n/a
B n/a
C 40%
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate; water In dichloromethane; acetonitrile at 0 - 20℃; for 1.5h;A n/a
B n/a
C 40%
(1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one
95589-30-3

(1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With hydrogenchloride; sodium tetrahydroborate 2) MeOH, reflux, 3h; Yield given. Multistep reaction;
1-O-β-D-glucosyl-(2R)-3-chloropropylene glycol

1-O-β-D-glucosyl-(2R)-3-chloropropylene glycol

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With β-galactosidase In various solvent(s) at 35℃;
barium D-3-chloropropane-1,2-diol-1-phosphate

barium D-3-chloropropane-1,2-diol-1-phosphate

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With ethanol Yield given. Yields of byproduct given;
3-monochloro-1,2-propanediol
96-24-2

3-monochloro-1,2-propanediol

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

C

D-3-chloropropane-1,2-diol-1-phosphate

D-3-chloropropane-1,2-diol-1-phosphate

Conditions
ConditionsYield
With sodium hydroxide; phospho(enol)pyruvic acid mono potassium salt; ATP; 2-hydroxyethanethiol; magnesium chloride In water at 27℃; for 120h; pH=7.5; Yield given. Yields of byproduct given;
C13H21ClO3

C13H21ClO3

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With hydrogenchloride In methanol for 3h; Heating; Yield given;
1,2-diacetoxy-3-chloro-propane
869-50-1

1,2-diacetoxy-3-chloro-propane

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With porcine pancreatic lipase; sodium methylate 1) H2O (pH:7), r.t., 2) MeOH, r.t., 4h; Multistep reaction;
(S)-1,2-Diacetoxy-3-chloropropane
78692-88-3

(S)-1,2-Diacetoxy-3-chloropropane

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With sulfuric acid for 1h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With potassium dioxotetrahydroxoosmate(VI); potassium carbonate; potassium hexacyanoferrate(III); 1,4-bis(dihydroquinidinyl)anthraquinone In water; tert-butyl alcohol at 0℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With dihydrogen peroxide In acetonitrile at 25℃; for 0.416667h; Title compound not separated from byproducts.;
3-monochloro-1,2-propanediol
96-24-2

3-monochloro-1,2-propanediol

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With sodium hydroxide; sodium azide; acid phosphatase; pyruvate kinase; phosphoenolpyruvic acid; glycerol kinase from Streptomyces canus; potassium chloride; ATP; 2-hydroxyethanethiol; magnesium chloride 1.) H2O, 25 deg C; Yield given. Multistep reaction. Yields of byproduct given;
epichlorohydrin
106-89-8

epichlorohydrin

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With polistyrene-bound (R,R)-N-(3,5-di-t-butyl-6-hydroxy)benzylidene-N'-(3-t-butyl-2,5-dihydroxy)benzylidene-1,2-cyclohexanediamine; water In dichloromethane for 3h; Ambient temperature; Yield given; Yields of byproduct given. Title compound not separated from byproducts;
With water Jacobsen kinetic hydrolytic resolution;
Stage #1: epichlorohydrin With phthalic anhydride; C64H74Al2Cl2N4O4; bis(triphenylphosphine)iminium chloride In toluene at 25℃; for 3h; Inert atmosphere;
Stage #2: With sodium hydroxide In tetrahydrofuran; methanol at 20℃; for 24h; Reagent/catalyst; Temperature; Inert atmosphere; enantioselective reaction;
A n/a
B n/a
epichlorohydrin
106-89-8

epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

C

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

D

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With water; poly(Co(III)(OTs)-salen-norbornene) In chlorobenzene at 20℃; for 0.5h; Product distribution; Further Variations:; Catalysts; reaction times;
Co(Salen)/SBA-16-C8 In tetrahydrofuran; water at 24.84℃; for 20h;
With C118H146Co2N4O14S2; water In acetonitrile at 20℃; optical yield given as %ee; enantioselective reaction;
3-chloro-1-hydroxypropan-2-one
24423-98-1

3-chloro-1-hydroxypropan-2-one

A

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

B

(S)-3-chloropropan-1,2-diol
60827-45-4

(S)-3-chloropropan-1,2-diol

Conditions
ConditionsYield
With potassium dihydrogenphosphate; D-glucose In water at 30℃; for 24h; pH=5.5; Aqueous phophate buffer; Microbiological reaction;A n/a
B n/a
With potassium dihydrogenphosphate; D-glucose In water at 30℃; for 24h; pH=5.5; Aqueous phophate buffer; Microbiological reaction;A n/a
B n/a
With potassium dihydrogenphosphate; D-glucose In water at 30℃; for 24h; pH=5.5; Aqueous phophate buffer; Microbiological reaction;A n/a
B n/a
3-chloro-1-hydroxypropan-2-one
24423-98-1

3-chloro-1-hydroxypropan-2-one

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With Candida-derived reductase; NADH at 30℃; for 2h; pH=6.5; Aqueous phophate buffer; Enzymatic reaction;n/a
With potassium dihydrogenphosphate; D-glucose In water at 30℃; for 24h; pH=5.5; Aqueous phophate buffer; Microbiological reaction;n/a
With potassium dihydrogenphosphate; D-glucose In water at 30℃; for 24h; pH=5.5; Aqueous phophate buffer; Microbiological reaction;n/a
(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

A

(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

B

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With (R,R)-Jacobsen catalyst; waterA n/a
B n/a
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Conditions
ConditionsYield
With sulfuric acid In water at 108℃; for 6h;
With sulfuric acid In water at 108℃; for 6h;
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

phosphorylcholine chloride
107-73-3

phosphorylcholine chloride

L-glycero-3-phosphorylcholine
28319-77-9

L-glycero-3-phosphorylcholine

Conditions
ConditionsYield
Stage #1: phosphorylcholine chloride With potassium hydroxide In methanol for 1h;
Stage #2: (2R)-3-chloro-1,2-propanediol In methanol at 65℃; for 16h; Temperature;
99%
Stage #1: phosphorylcholine chloride With potassium hydroxide In ethanol for 0.5h;
Stage #2: (2R)-3-chloro-1,2-propanediol In ethanol at 75 - 85℃; for 6h;
79.6%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(R)-3-chloro-2-hydroxypropyl 4-methylbenzenesulfonate
83398-53-2

(R)-3-chloro-2-hydroxypropyl 4-methylbenzenesulfonate

Conditions
ConditionsYield
With pyridine for 1h; Ambient temperature;98.6%
With hydrogenchloride75%
With pyridine
With pyridine at 0 - 20℃; for 1h;
heptatriaconta-6,9,28,31-tetraen-19-one

heptatriaconta-6,9,28,31-tetraen-19-one

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

4-(R)-4-chloromethyl-2,2-di-octadeca-9,12-dienyl-[1,3]dioxolane

4-(R)-4-chloromethyl-2,2-di-octadeca-9,12-dienyl-[1,3]dioxolane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene for 72h; Reflux; Water removal;97%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(S)-(-)-1-(2,3-dihydroxypropyl)-4-(dimethylamino)pyridinium chloride
942209-57-6

(S)-(-)-1-(2,3-dihydroxypropyl)-4-(dimethylamino)pyridinium chloride

Conditions
ConditionsYield
In acetonitrile at 65℃; for 24h;96%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

trimethylamine
75-50-3

trimethylamine

(S)-2,3-dihydroxypropyltrimethylammonium chloride

(S)-2,3-dihydroxypropyltrimethylammonium chloride

Conditions
ConditionsYield
In water at 90℃; for 16h;95.7%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

2-benzyloxy-3-methylphenol
150710-99-9

2-benzyloxy-3-methylphenol

(R)-2-benzyloxy-3-(2,3-dihydroxypropoxy)toluene
335280-94-9

(R)-2-benzyloxy-3-(2,3-dihydroxypropoxy)toluene

Conditions
ConditionsYield
Stage #1: 2-benzyloxy-3-methylphenol; cesium fluoride In N,N-dimethyl-formamide for 1h;
Stage #2: (2R)-3-chloro-1,2-propanediol In N,N-dimethyl-formamide at 60℃; for 5h; Further stages.;
95%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

dimethylglyoxal
431-03-8

dimethylglyoxal

trimethyl orthoformate
149-73-5

trimethyl orthoformate

(2R,3R)-5-(chloromethyl)-2,3-dimethoxy-2,3-dimethyl-1,4-dioxane

(2R,3R)-5-(chloromethyl)-2,3-dimethoxy-2,3-dimethyl-1,4-dioxane

Conditions
ConditionsYield
With camphor-10-sulfonic acid In methanol at 90℃;95%
With camphor-10-sulfonic acid In methanol for 2h; Heating;
2,4-dichloro-α-oxo-benzeneacetic ethyl ester
34966-51-3

2,4-dichloro-α-oxo-benzeneacetic ethyl ester

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(1S,5S)-5-(2,4-dichlorophenyl)-3,6,8-trioxabicyclo[3.2.1]octan-4-one

(1S,5S)-5-(2,4-dichlorophenyl)-3,6,8-trioxabicyclo[3.2.1]octan-4-one

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃;95%
phthalimide
136918-14-4

phthalimide

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

1H-isoindole-1,3(2H)-dione, 2-[(2S)-2,3-dihydroxypropyl]
119835-88-0

1H-isoindole-1,3(2H)-dione, 2-[(2S)-2,3-dihydroxypropyl]

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 110℃; for 5h; Reagent/catalyst; Temperature; Time; Gabriel Amine Synthesis;94.9%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(R)-4-chloromethyl-[1,3,2]dioxathiolane 2-oxide
146864-18-8

(R)-4-chloromethyl-[1,3,2]dioxathiolane 2-oxide

Conditions
ConditionsYield
With thionyl chloride In dichloromethane94%
With thionyl chloride In tetrachloromethane for 2h; Reflux; Inert atmosphere;94%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

2-allyloxyphenol
1126-20-1

2-allyloxyphenol

(R)-2-allyloxy-1-(2,3-dihydroxypropoxy)benzene
66901-82-4

(R)-2-allyloxy-1-(2,3-dihydroxypropoxy)benzene

Conditions
ConditionsYield
Stage #1: 2-allyloxyphenol; cesium fluoride In N,N-dimethyl-formamide for 1h;
Stage #2: (2R)-3-chloro-1,2-propanediol In N,N-dimethyl-formamide at 60℃; for 5h; Further stages.;
93%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(R)-(-)-1-(tert-butylmethylsilanyloxy)-3-chloropropan-2-ol
136984-26-4

(R)-(-)-1-(tert-butylmethylsilanyloxy)-3-chloropropan-2-ol

Conditions
ConditionsYield
With 1H-imidazole In DMF (N,N-dimethyl-formamide) at 0 - 20℃;92.4%
2’2’2’-trifluoro-2,4-dichloroacetophenone
92736-81-7

2’2’2’-trifluoro-2,4-dichloroacetophenone

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

((4R)-2-(2,4-dichlorophenyl)-2-trifluoromethyl-1,3-dioxolan-4-yl)methanol

((4R)-2-(2,4-dichlorophenyl)-2-trifluoromethyl-1,3-dioxolan-4-yl)methanol

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;91%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

para-thiocresol
106-45-6

para-thiocresol

(R)-3-p-Tolylsulfanyl-propane-1,2-diol
127634-04-2

(R)-3-p-Tolylsulfanyl-propane-1,2-diol

Conditions
ConditionsYield
With sodium hydroxide at 100℃; for 2h;90%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

acetone
67-64-1

acetone

(R)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane
57044-24-3

(R)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 50℃; for 4h;90%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone
58905-16-1

1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone

C13H12Cl3N3O2

C13H12Cl3N3O2

Conditions
ConditionsYield
With methanesulfonic acid In toluene at 40℃; for 4h;90%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

N,N-dimethylammonium chloride
506-59-2

N,N-dimethylammonium chloride

(S)-3-(N,N-dimethylamino)propane-1,2-diol
666234-82-8

(S)-3-(N,N-dimethylamino)propane-1,2-diol

Conditions
ConditionsYield
With sodium hydroxide In water at 20℃; for 18h;89%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(R)-oxiranemethanol
57044-25-4

(R)-oxiranemethanol

Conditions
ConditionsYield
With potassium carbonate In dichloromethane for 18h; Ambient temperature;88%
With potassium carbonate In dichloromethane other reagent: Cs2CO3;
With potassium phosphate In dichloromethane for 3h; Product distribution / selectivity; Heating / reflux;
With potassium carbonate In dichloromethane at 20℃; for 24h;
With potassium carbonate In dichloromethane at 20℃; for 20h;
2-(4-methylamino-phenyl)-benzofuran-5-ol

2-(4-methylamino-phenyl)-benzofuran-5-ol

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(R)-3-((2-(4-(methylamino)phenyl)benzofuran-5-yl)oxy)propane-1,2-diol

(R)-3-((2-(4-(methylamino)phenyl)benzofuran-5-yl)oxy)propane-1,2-diol

Conditions
ConditionsYield
Stage #1: 2-(4-methylamino-phenyl)-benzofuran-5-ol With sodium hydroxide In ethanol; water at 80℃; for 1h;
Stage #2: (2R)-3-chloro-1,2-propanediol In ethanol; water at 80℃; for 3h;
87.7%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

phosphorylcholine chloride, calcium salt
4826-71-5

phosphorylcholine chloride, calcium salt

glycerolcholine phosphate
34688-34-1

glycerolcholine phosphate

Conditions
ConditionsYield
Stage #1: phosphorylcholine chloride, calcium salt With potassium oxalate In water at 20℃; for 2h;
Stage #2: (2R)-3-chloro-1,2-propanediol With potassium hydroxide In ethanol for 6h;
86%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(R)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane
57044-24-3

(R)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetone85%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

(R)-1-[(tert-butyldiphenylsilyl)oxy]-3-chloropropan-2-ol

(R)-1-[(tert-butyldiphenylsilyl)oxy]-3-chloropropan-2-ol

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 0 - 20℃; for 4h;85%
(2Z,5Z)-5-[(3-chloro-4-hydroxyphenyl)methylene]-3-(o-tolyl)-2-propyliminothiazolidin-4-one
1029435-58-2

(2Z,5Z)-5-[(3-chloro-4-hydroxyphenyl)methylene]-3-(o-tolyl)-2-propyliminothiazolidin-4-one

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

Ponesimod

Ponesimod

Conditions
ConditionsYield
With potassium tert-butylate In ethanol at 20 - 88℃; for 24.5h;84%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(R)-5-(chloromethyl)-2,2,3,3,8,8,9,9-octamethyl-4,7-dioxa-3,8-disiladecane

(R)-5-(chloromethyl)-2,2,3,3,8,8,9,9-octamethyl-4,7-dioxa-3,8-disiladecane

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃;84%
With 1H-imidazole In dichloromethane
benzophenone
119-61-9

benzophenone

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(4R)-4-(chloromethyl)-2,2-diphenyl-1,3-dioxolane
139892-51-6

(4R)-4-(chloromethyl)-2,2-diphenyl-1,3-dioxolane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Reflux;82%
With toluene-4-sulfonic acid In toluene Heating;
With toluene-4-sulfonic acid In toluene for 18h; Reflux; Dean-Stark;
1H-indol-4-ol
2380-94-1

1H-indol-4-ol

(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

(R)-3-(4-indolyloxy)-propane-1,2-diol
74784-71-7

(R)-3-(4-indolyloxy)-propane-1,2-diol

Conditions
ConditionsYield
Stage #1: 1H-indol-4-ol With potassium carbonate In acetonitrile for 2h; Reflux;
Stage #2: (2R)-3-chloro-1,2-propanediol In acetonitrile for 16h; Reflux;
82%
(2R)-3-chloro-1,2-propanediol
57090-45-6

(2R)-3-chloro-1,2-propanediol

7-(4-chlorophenylthio)-6,7-dihydro-1-(phenylsulfonyl)-1H-indol-4(5H)-one
157396-11-7

7-(4-chlorophenylthio)-6,7-dihydro-1-(phenylsulfonyl)-1H-indol-4(5H)-one

A

(R)-(-)-1-chloro-3-<(1-phenylsulfonyl)-1H-indol-4-yloxy>-2-propanol

(R)-(-)-1-chloro-3-<(1-phenylsulfonyl)-1H-indol-4-yloxy>-2-propanol

B

4-(4-chlorophenylthio)-1-(phenylsulfonyl)-1H-indole

4-(4-chlorophenylthio)-1-(phenylsulfonyl)-1H-indole

Conditions
ConditionsYield
With toluene-4-sulfonic acid; copper dichloride In benzene for 1h; Heating;A 81%
B 6%
With toluene-4-sulfonic acid In benzene for 1.5h; Heating;A 77%
B 4%
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