DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:181269-69-2
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryProduct Name: 1-BOC-3-METHYL-PIPERIDIN-4-ONE Synonyms: N-TERT-BUTOXYCARBONYL-3-METHYL-4-PIPERIDONE;1-BOC-3-METHYL-PIPERIDIN-4-ONE;tert-Butyl 3-methyl-4-oxopiperidine-1-carboxylate;N-Boc-3-methyl-4-piperidone;3-Methyl-4-oxo-piperidine-1
Cas:181269-69-2
Min.Order:1 Gram
FOB Price: $8900.0
Type:Lab/Research institutions
inquiry1-BOC-3-METHYL-PIPERIDIN-4-ONE Basic information Product Name: 1-BOC-3-METHYL-PIPERIDIN-4-ONE Synonyms: N-TERT-BUTOXYCARBONYL-3-METHYL-4-PIPERIDONE;1-BOC-3-METHYL-PIPERIDIN-4-ONE;tert-Butyl 3-methyl-4-oxopiperidine-1-carboxylate;N-Boc-3-methyl-
Cas:181269-69-2
Min.Order:1 Gram
Negotiable
Type:Other
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:181269-69-2
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:181269-69-2
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1-BOC-3-METHYL-PIPERIDIN-4-ONE CAS:181269-69-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality o
Cas:181269-69-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:181269-69-2
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:181269-69-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:181269-69-2
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:181269-69-2
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product
Cas:181269-69-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:181269-69-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryChemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:181269-69-2
Min.Order:100 Gram
Negotiable
Type:Other
inquiryEstablished in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site
Cas:181269-69-2
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:181269-69-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Cas:181269-69-2
Min.Order:1 Milligram
Negotiable
Type:Trading Company
inquiryProduct Name: 1-BOC-3-METHYL-PIPERIDIN-4-ONE Synonyms: N-TERT-BUTOXYCARBONYL-3-METHYL-4-PIPERIDONE;1-BOC-3-METHYL-PIPERIDIN-4-ONE;tert-Butyl 3-methyl-4-oxopiperidine-1-carboxylate;N-Boc-3-methyl-4-piperidone;3-Methyl-4-oxo-piperidine-1-carboxyl
Cas:181269-69-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:181269-69-2
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryHunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
Cas:181269-69-2
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:181269-69-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:181269-69-2
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryProductName:tert-Butyl 3-methyl-4-oxopiperidine-1-carboxylate Synonyms:N-Boc-3-methyl-4-piperidone;1-BOC-3-METHYL-PIPERIDIN-4-ONE; CAS:181269-69-2 Molecular Formula: C11H19NO3 Molecular Weight:213.27300 Purity:≥98% Appearance: light
Cas:181269-69-2
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryShanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We specialize in manufacturing high quality of Advanced Intermediates, Sp
Cas:181269-69-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:181269-69-2
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiryShanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service
Cas:181269-69-2
Min.Order:0
Negotiable
Type:Trading Company
inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:181269-69-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryThe process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai
Cas:181269-69-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:181269-69-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAcmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
Cas:181269-69-2
Min.Order:1 bottle
Negotiable
Type:Lab/Research institutions
inquiry1-Benzyl-3-methyl-4-piperidon
di-tert-butyl dicarbonate
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
With hydrogen; palladium dihydroxide In ethyl acetate under 2068.65 Torr; for 24h; | 100% |
With hydrogen; palladium 10% on activated carbon In ethanol at 20℃; under 2585.81 Torr; for 4h; | 97% |
With hydrogen; palladium(II) hydroxide In methanol at 20℃; under 2844.39 Torr; | 95% |
N-tert-butyloxycarbonylpiperidin-4-one
methyl iodide
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: methyl iodide In tetrahydrofuran at -78 - 20℃; for 3h; | 45% |
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere; Stage #2: methyl iodide In tetrahydrofuran at 20℃; for 3h; | 28% |
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With potassium hexamethylsilazane In tetrahydrofuran; toluene at 20℃; for 2h; Stage #2: methyl iodide In tetrahydrofuran; toluene at 20℃; | 22.5% |
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With sodium hydride In tetrahydrofuran; mineral oil at 20℃; Stage #2: methyl iodide In tetrahydrofuran; mineral oil | 16% |
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With sodium hydride In tetrahydrofuran at 20℃; for 0.5h; Stage #2: methyl iodide In tetrahydrofuran at 20℃; for 18h; | 10% |
3-methyl-4-piperidone
di-tert-butyl dicarbonate
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
With N,N-dimethylethylenediamine In dichloromethane at 20℃; for 2.5h; | |
With dmap; triethylamine In tetrahydrofuran; water at 20℃; for 18h; |
di-tert-butyl dicarbonate
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: 1-Benzyl-3-methyl-4-piperidon With hydrogenchloride; hydrogen; palladium dihydroxide In 1,4-dioxane; methanol under 2585.81 Torr; Stage #2: di-tert-butyl dicarbonate With triethylamine In tetrahydrofuran for 2h; |
di-tert-butyl dicarbonate
C14H23NO5
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: C14H23NO5 With hydrogenchloride In water for 48h; Reflux; Stage #2: di-tert-butyl dicarbonate With sodium carbonate In tetrahydrofuran; water |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
tert-Butyl 4-hydroxy-3-methylpiperidine-1-carboxylate
Conditions | Yield |
---|---|
With sodium tetrahydroborate In methanol at 0 - 20℃; for 3.5h; | 100% |
With methanol; sodium tetrahydroborate at 0 - 25℃; for 3.5h; | 100% |
With sodium tetrahydroborate In ethanol at 0℃; for 0.5h; | 88% |
N,N-phenylbistrifluoromethane-sulfonimide
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
3-methyl-4-trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1.5h; Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -78 - 25℃; for 2.5h; | 97% |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With sodium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1.5h; Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at 20℃; for 16h; | 78% |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -78 - 0℃; for 1h; | 61% |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.666667h; Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -78 - 25℃; for 3h; | 198 mg |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With lithium hexamethyldisilazane In tetrahydrofuran at -70℃; for 1h; Inert atmosphere; Stage #2: N,N-phenylbistrifluoromethane-sulfonimide In tetrahydrofuran at -70 - 0℃; for 4h; |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; (S)-2-(2-(methylsulfonyl)ethyl)pyrrolidine hydrochloride With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 6h; Stage #2: With hydrogenchloride In 1,4-dioxane; dichloromethane at 20℃; for 4h; | 96% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
diethyl {3-[(5-chloropyridin-2-yl)oxy]benzyl}phosphonate
Conditions | Yield |
---|---|
With potassium tert-butylate In tetrahydrofuran at 20℃; for 2h; | 90% |
With potassium tert-butylate In tetrahydrofuran at 20℃; for 2h; |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
2-(5-methoxy-2-nitrophenyl)-ethylamine
tert-butyl 4-[2-(5-methoxy-2-nitro-phenyl)-ethylamino]-3-methyl-piperidine-1-carboxylate
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃; for 3h; | 90% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
trimethylsulfoxonium iodide
Conditions | Yield |
---|---|
With potassium tert-butylate In 1,2-dimethoxyethane; dimethyl sulfoxide at 0 - 5℃; for 1h; | 90% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
phenylmagnesium bromide
Conditions | Yield |
---|---|
In tetrahydrofuran at 0 - 20℃; for 24h; | 84% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Methyltriphenylphosphonium bromide
tert-butyl 3-methyl-4-methylidenepiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: Methyltriphenylphosphonium bromide With n-butyllithium In tetrahydrofuran at 0℃; Stage #2: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate In tetrahydrofuran at 20℃; for 1h; | 83% |
Stage #1: Methyltriphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere; Stage #2: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate In tetrahydrofuran at 20℃; for 18h; Inert atmosphere; | 60% |
With potassium tert-butylate In dimethyl sulfoxide at 20℃; for 16h; |
bromochlorobenzene
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: bromochlorobenzene With n-butyllithium In tetrahydrofuran; hexane at -78℃; Stage #2: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate In tetrahydrofuran; hexane at -78 - -20℃; Stage #3: With ammonium chloride In tetrahydrofuran; hexane; water | 83% |
Stage #1: bromochlorobenzene With n-butyllithium In tetrahydrofuran; hexanes at -78℃; for 0.75h; Stage #2: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate In tetrahydrofuran; hexanes at -78℃; for 2h; | 79% |
diethoxyphosphoryl-acetic acid ethyl ester
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
sodium methylate
4-methoxycarbonylmethylene-3-methylpiperidine-1-carboxylic acid t-butyl ester
Conditions | Yield |
---|---|
In tetrahydrofuran; methanol at 20℃; for 4h; | 82.5% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
tert-butyl 4-amino-3-methylpiperidine-1-carboxylate
Conditions | Yield |
---|---|
With ammonium formate; sodium cyanoborohydride In methanol at 30℃; for 16h; Temperature; Molecular sieve; | 80% |
With ammonium formate; sodium cyanoborohydride In methanol at 20℃; for 3h; Molecular sieve; | 60% |
With formic acid; ammonium formate; sodium cyanoborohydride In methanol at 20℃; for 2h; |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
2-[3-(diethoxyphosphorylmethyl)phenoxy]-5-(trifluoromethyl)pyridine
2-{3-[(3-methylpiperidin-4-ylidene)methyl]phenoxy}-5-(trifluoromethyl)pyridine
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; 2-[3-(diethoxyphosphorylmethyl)phenoxy]-5-(trifluoromethyl)pyridine With potassium tert-butylate In tetrahydrofuran at 20℃; for 1h; Stage #2: With trifluoroacetic acid In dichloromethane at 20℃; for 1h; | 79% |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; 2-[3-(diethoxyphosphorylmethyl)phenoxy]-5-(trifluoromethyl)pyridine With potassium tert-butylate In tetrahydrofuran at 20℃; for 1h; Stage #2: With trifluoroacetic acid In dichloromethane at 20℃; for 1h; | 79% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
3-methyl-4-piperidone
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: With water In dichloromethane; water | 75% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
trimethylsulfoxonium iodide
1,1-dimethylethyl 4-methyl-1-oxa-6-azaspiro[2.5]octane-6-carboxylate
Conditions | Yield |
---|---|
Stage #1: trimethylsulfoxonium iodide With sodium hydride In dimethyl sulfoxide; mineral oil at 0 - 20℃; for 2h; Stage #2: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate In dimethyl sulfoxide; mineral oil at 0 - 20℃; for 2h; | 75% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
methyl (S)-3-(pyrrolidin-2-yl)propanoate
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃; for 16h; | 75% |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; methyl (S)-3-(pyrrolidin-2-yl)propanoate In 1,2-dichloro-ethane at 20℃; for 0.5h; Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; | 37% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Diethyl 3-(5-bromopyridin-2-yloxy)benzylphosphonate
5-bromo-2-{3-[(3-methylpiperidin-4-ylidene)methyl]phenoxy}pyridine
Conditions | Yield |
---|---|
With potassium tert-butylate In tetrahydrofuran at 20℃; for 2h; | 72% |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; Diethyl 3-(5-bromopyridin-2-yloxy)benzylphosphonate With potassium tert-butylate In tetrahydrofuran at 20℃; for 2h; Stage #2: With trifluoroacetic acid In dichloromethane at 20℃; for 1h; | 72% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
benzyltriphenylphosphonium bromide
Conditions | Yield |
---|---|
Stage #1: benzyltriphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 20℃; for 1h; Stage #2: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate In tetrahydrofuran at 20℃; for 3h; | 63% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
2-propynamide
tert-butyl 8-methyl-2-oxo-1,2,7,8-tetrahydro-1,6-naphthyridine-6(5H)-carboxylate
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With pyrrolidine In toluene for 5h; Reflux; Stage #2: 2-propynamide In toluene Reflux; | 55% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
p-tolylsulfonylmethyl isocyanide
Conditions | Yield |
---|---|
With potassium tert-butylate In 1,2-dimethoxyethane at 0 - 25℃; for 16h; Inert atmosphere; | 50.4% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide
3-methyl-4-trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With potassium hexamethylsilazane In tetrahydrofuran at -78 - 20℃; for 3.5h; Stage #2: N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide In tetrahydrofuran at -78 - 20℃; | 47% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
oxalic acid diethyl ester
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere; Stage #2: oxalic acid diethyl ester In tetrahydrofuran at 20℃; for 2h; | 45.6% |
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate With lithium hexamethyldisilazane In tetrahydrofuran at -60℃; for 0.5h; Stage #2: oxalic acid diethyl ester at -60 - 20℃; for 1h; |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; 2-iodo-1-(2,2,2-trifluoroethyl)-1H-indol-4-amine With chloro-trimethyl-silane In N,N-dimethyl-formamide at 0℃; for 2h; Stage #2: With borane-THF In N,N-dimethyl-formamide at 0 - 25℃; for 1h; Temperature; Reagent/catalyst; Inert atmosphere; | 45.28% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
(S)-1-Pyrrolidin-2-yl-methanol
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 16h; | 40% |
2-cyanomethylbenzothiazole
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
With morpholine; sulfur at 85℃; for 12h; | 39% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
N,N-dimethyl-formamide dimethyl acetal
tert-butyl 8-methyl-2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; N,N-dimethyl-formamide dimethyl acetal at 80℃; for 12h; Stage #2: 2-methyl-2-thiopseudouronium sulfate With sodium ethanolate In ethanol at 80℃; for 12.5h; | 36% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
CYANAMID
C12H19N3O2S
Conditions | Yield |
---|---|
With pyridine; sulfur at 100℃; for 3h; | 31.3% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate; (S)-2-(pyrrolidin-2-yl)ethane-1-sulfonamide With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 16h; Stage #2: With trifluoroacetic acid In dichloromethane at 20℃; for 1h; | 22% |
tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate
(S)-1-phenyl-ethylamine
(3R,4R)-3-methyl-4-(1-(S)-phenyl-ethylamino)-piperidine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With sodium triacetoxyborohydride In dichloromethane at 20℃; | 10% |
With sodium tris(acetoxy)borohydride In dichloromethane at 20℃; | 10% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View