1. We integrate research and development, production, and sales. A 1800 square meter research and development center,The company has conducted over 50 research and development and technical service projects annually, applied for more than 10 patents,
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Trading Company
inquiry1. made in GMP plant, commerially 2. usually have it in stock 3. can supply at large quantity 4. audit accepted. related documents are available to offer and audited by many clients, such as lupin, msn, dr reddy etc 5. chromatographic p
Cas:181289-15-6
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:181289-15-6
Min.Order:1 Metric Ton
Negotiable
Type:Manufacturers
inquiry3-(Carbamoylmethyl)-5-methyl-hexanoic acid 181289-15-6 M f:C9H17NO3 3-(Carbamoylmethyl)-5-methyl-hexanoic acid 3-(Carbamoylmethyl)-5-methyl-hexanoic acid Molecular formula:C9H17NO3 CAS No181289-15-6 Appe
Cas:181289-15-6
Min.Order:1 Kilogram
Negotiable
Type:Other
inquiryProduct Description Product website: http://www.finerchem.com Product Name 3-Carbamoymethyl-5-methylhexanoic acid CAS No.
Cas:181289-15-6
Min.Order:1 Gram
FOB Price: $8.0
Type:Lab/Research institutions
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:181289-15-6
Min.Order:1
Negotiable
Type:Other
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:181289-15-6
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:181289-15-6
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryTIANFUCHEM--181289-15-6--3-Carbamoymethyl-5-methylhexanoic acid factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established
Cas:181289-15-6
Min.Order:1 Metric Ton
FOB Price: $2000.0
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryName: 3-Carbamoymethyl-5-methylhexanoic acid Synonyms: 3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid CAS: 181289-15-6 MF: C9H17NO3 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Organ
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;
Cas:181289-15-6
Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White crystalline granules or powder. Storage:Store in seale
Cas:181289-15-6
Min.Order:100 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:181289-15-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the
Cas:181289-15-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $45.0
Type:Trading Company
inquiryAmisulpride CAS: 71675-85-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
Cas:181289-15-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:181289-15-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryProduct Detail Minimum Order Qty. 10 Gram
Cas:181289-15-6
Min.Order:10 Gram
Negotiable
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:181289-15-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:181289-15-6
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Cas:181289-15-6
Min.Order:0
Negotiable
Type:Manufacturers
inquiryAppearance:off-white crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common product
Cas:181289-15-6
Min.Order:100 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:181289-15-6
Min.Order:1 Kilogram
FOB Price: $1.0 / 100000.0
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:181289-15-6
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:181289-15-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:181289-15-6
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry3-isobutylglutaric anhydride
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
With ammonia In water at -10 - 40℃; for 1.5h; | 100% |
With ammonium hydroxide at 10℃; for 2h; Temperature; | 95% |
Stage #1: 3-isobutylglutaric anhydride With ammonia In tert-butyl methyl ether; water at 0 - 20℃; Stage #2: With hydrogenchloride In tert-butyl methyl ether; water pH=2; | 80.4% |
5-methyl-3-carboxymethylhexanoic acid
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
With urea In 5,5-dimethyl-1,3-cyclohexadiene at 130℃; for 3h; Temperature; Solvent; | 93.5% |
With pyridine; di-tert-butyl dicarbonate; ammonium bicarbonate In acetonitrile at 5 - 20℃; for 0.5h; Solvent; | 72.4% |
With hydrogenchloride; ammonium hydroxide; acetic anhydride In tert-butyl methyl ether; water; ethyl acetate |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
With potassium carbonate In 5,5-dimethyl-1,3-cyclohexadiene; water at 30℃; for 1h; Reagent/catalyst; Temperature; | 86.6% |
Stage #1: 3-isobutylglutarimide With water; sodium hydroxide at 60℃; for 1h; Stage #2: With hydrogenchloride; water | 31 g |
With sodium hydroxide at 50 - 90℃; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
With water; sodium hydroxide at 65℃; for 0.583333h; Temperature; | 79% |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
With water; lithium hydroxide In tetrahydrofuran; methanol at 20℃; for 3h; | 76% |
(1'SR,3 SR)-1-(1'-napthyl)ethyl-3-(carboxylomethyl)-5-methylhexanoate
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Stage #1: (1'SR,3 SR)-1-(1'-napthyl)ethyl-3-(carboxylomethyl)-5-methylhexanoate With chloroformic acid ethyl ester; triethylamine In acetone at -20℃; Inert atmosphere; Stage #2: With ammonia In water; acetone at -20℃; for 2h; Stage #3: With sodium hydroxide In water at 0℃; | 58% |
tert-butyl methyl ether
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
With ammonium hydroxide In water |
(S)‑3‑carbamoylmethyl‑5‑methylhexanoic acid
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Stage #1: (S)‑3‑carbamoylmethyl‑5‑methylhexanoic acid With toluene-4-sulfonic acid In toluene Reflux; Stage #2: With sodium hydroxide In water; toluene at 25 - 65℃; Stage #3: With hydrogenchloride In water at 10 - 15℃; for 1.5h; Product distribution / selectivity; |
isovaleraldehyde
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: di-n-propylamine; ethyl 2-cyanoacetate / cyclohexane / 2 h / 25 - 30 °C / Reflux 1.2: 5.17 h / 25 - 50 °C 1.3: 48 h / Reflux 2.1: urea / 12 h / 130 - 135 °C 2.2: 60 - 90 °C View Scheme | |
Multi-step reaction with 5 steps 1.1: piperidine; pyridine; acetic acid / hexane / 48 h / Reflux; Inert atmosphere 2.1: di-n-propylamine / 16 h / 15 - 55 °C 3.1: hydrogen bromide / water / 72 h / 100 °C 4.1: acetyl chloride / 3.08 h / 20 - 55 °C / Inert atmosphere 5.1: ammonia / water; tert-butyl methyl ether / 0 - 20 °C 5.2: pH 2 View Scheme | |
Multi-step reaction with 6 steps 1.1: piperidine; pyridine; acetic acid / hexane / 48 h / Reflux; Inert atmosphere 2.1: di-n-propylamine / 16 h / 15 - 55 °C 3.1: hydrogen bromide / water / 72 h / 100 °C 4.1: acetyl chloride / 3.08 h / 20 - 55 °C / Inert atmosphere 5.1: 1,4-diaza-bicyclo[2.2.2]octane / tert-butyl methyl ether / 2 h / -78 °C / Inert atmosphere 6.1: chloroformic acid ethyl ester; triethylamine / acetone / -20 °C / Inert atmosphere 6.2: 2 h / -20 °C 6.3: 0 °C View Scheme | |
Multi-step reaction with 4 steps 1: tetramethyl ammoniumhydroxide; trimethyldodecylammonium chloride / ethanol / 6 h / 25 °C 2: water; hydrogenchloride / 30 h / 140 °C / pH 1 - 2 3: acetic anhydride / 2 h / 120 °C 4: ammonium hydroxide / 2 h / 10 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: piperidine / hexane / 100 °C / Dean-Stark 2.1: piperidine / 2 h / 55 °C 2.2: 72 h / 100 - 120 °C 3.1: 5 h / 160 °C 4.1: sodium hydroxide; water / 0.58 h / 65 °C View Scheme |
diethyl 2-(3-methylbutylidene)malonate
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: di-n-propylamine / 16 h / 15 - 55 °C 2.1: hydrogen bromide / water / 72 h / 100 °C 3.1: acetyl chloride / 3.08 h / 20 - 55 °C / Inert atmosphere 4.1: ammonia / water; tert-butyl methyl ether / 0 - 20 °C 4.2: pH 2 View Scheme | |
Multi-step reaction with 5 steps 1.1: di-n-propylamine / 16 h / 15 - 55 °C 2.1: hydrogen bromide / water / 72 h / 100 °C 3.1: acetyl chloride / 3.08 h / 20 - 55 °C / Inert atmosphere 4.1: 1,4-diaza-bicyclo[2.2.2]octane / tert-butyl methyl ether / 2 h / -78 °C / Inert atmosphere 5.1: chloroformic acid ethyl ester; triethylamine / acetone / -20 °C / Inert atmosphere 5.2: 2 h / -20 °C 5.3: 0 °C View Scheme |
2-isobutyl-propane-1,1,3,3-tetracarboxylic acid tetraethyl ester
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydrogen bromide / water / 72 h / 100 °C 2.1: acetyl chloride / 3.08 h / 20 - 55 °C / Inert atmosphere 3.1: ammonia / water; tert-butyl methyl ether / 0 - 20 °C 3.2: pH 2 View Scheme | |
Multi-step reaction with 4 steps 1.1: hydrogen bromide / water / 72 h / 100 °C 2.1: acetyl chloride / 3.08 h / 20 - 55 °C / Inert atmosphere 3.1: 1,4-diaza-bicyclo[2.2.2]octane / tert-butyl methyl ether / 2 h / -78 °C / Inert atmosphere 4.1: chloroformic acid ethyl ester; triethylamine / acetone / -20 °C / Inert atmosphere 4.2: 2 h / -20 °C 4.3: 0 °C View Scheme |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: water; hydrogenchloride / 30 h / 140 °C / pH 1 - 2 2: acetic anhydride / 2 h / 120 °C 3: ammonium hydroxide / 2 h / 10 °C View Scheme |
2‑cyano‑5‑methylhex‑2‑enoic acid methyl ester
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: piperidine / 2 h / 55 °C 1.2: 72 h / 100 - 120 °C 2.1: 5 h / 160 °C 3.1: sodium hydroxide; water / 0.58 h / 65 °C View Scheme |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(3R)‐3‐(carbamoylmethyl)‐5‐methylhexanoic acid
Conditions | Yield |
---|---|
With D-phenylglycine butyl ester In isopropyl alcohol Heating; | 90.39% |
With (R)-1-phenyl-ethyl-amine In methanol; chloroform at 25 - 40℃; for 3.16h; Solvent; Temperature; | 41% |
Stage #1: (±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid With (R)-1-phenyl-ethyl-amine In ethanol; chloroform for 0.75h; Reflux; Stage #2: With hydrogenchloride In ethanol; chloroform; water for 0.75h; Cooling; | 40% |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(R,S)-3-iso-butyl-4-aminobutyric acid
Conditions | Yield |
---|---|
With bromine; sodium hydroxide In water at 0 - 85℃; for 3h; Temperature; Large scale; | 89% |
With bromine; sodium hydroxide In water at 5 - 60℃; for 2h; | 81% |
Stage #1: (±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid With sodium hydroxide; water; bromine at 5 - 60℃; for 0.5h; Hofmann Rearrangement; Stage #2: With sulfuric acid In 2-methyl-propan-1-ol; water Stage #3: With tributyl-amine In 2-methyl-propan-1-ol at 2 - 10℃; for 1.5 - 2h; Product distribution / selectivity; | 80.4% |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(R)-1-phenyl-ethyl-amine
A
(R)-3-(carbamoylmethyl)-5-methylhexanoic acid (R)-(+)-α-phenylethylamine
Conditions | Yield |
---|---|
In chloroform at 55℃; for 1.5h; | A 79.2% B n/a |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
Quinine
Conditions | Yield |
---|---|
With acetone In water at 80℃; | 67.9% |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(R)-1-(1-Naphthyl)ethylamine
(R)-(+)-1-(1-naphthyl)ethylamine salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid
Conditions | Yield |
---|---|
In methanol; ethyl acetate at 25 - 68℃; Heating / reflux; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(2S)-2-phenylglycinol
(S)-(+)-phenylglycinol salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid
Conditions | Yield |
---|---|
In methanol; ethyl acetate at 25 - 68℃; Heating / reflux; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(R)-Phenylglycinol
(R)-(-)-phenylglycinol salt of (R)-(-)-3-(carbamoylmethyl)-5-methylhexanoic acid
Conditions | Yield |
---|---|
In 1,4-dioxane at 25 - 90℃; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
pregabilin
Conditions | Yield |
---|---|
Stage #1: (±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid With sodium hydroxide; water; bromine at 10 - 60℃; for 0.5 - 5.75h; Hofmann Rearrangement; Stage #2: With sulfuric acid In 2-methyl-propan-1-ol; water at 20℃; for 0.5 - 24h; Stage #3: With tributyl-amine In 2-methyl-propan-1-ol at 2℃; for 1.5 - 2h; Product distribution / selectivity; | |
Stage #1: (±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid With sodium hydroxide; water; bromine at 15 - 60℃; for 0.5h; Hofmann Rearrangement; Stage #2: With sulfuric acid In 2-methyl-propan-1-ol; water Stage #3: With tributyl-amine In 2-methyl-propan-1-ol; water at 2℃; for 2h; Product distribution / selectivity; | |
Multi-step reaction with 2 steps 1.1: chloroform / 0.5 h / 50 - 55 °C 2.1: sodium hydroxide; bromine / water / 1.25 h / -5 - 55 °C 2.2: 0 - 5 °C / pH 6.7 View Scheme | |
Multi-step reaction with 3 steps 1.1: chloroform / 0.92 h / 52.5 °C 2.1: hydrogenchloride / water / 22.5 - 42.5 °C 3.1: sodium hydroxide; sodium hypochlorite / water / 3.04 h / 7.5 - 42.5 °C 3.2: 0.29 h / 27.5 °C View Scheme |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
chloroformic acid ethyl ester
Conditions | Yield |
---|---|
Stage #1: (±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid; chloroformic acid ethyl ester With triethylamine In tetrahydrofuran at -10℃; for 0.5h; Stage #2: With sodium azide In tetrahydrofuran; water at -10℃; for 2h; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(R)-1-phenyl-ethyl-amine
(R)-3-(carbamoylmethyl)-5-methylhexanoic acid (R)-(+)-α-phenylethylamine
Conditions | Yield |
---|---|
In ethanol; chloroform at 30 - 55℃; for 1h; Product distribution / selectivity; | |
In chloroform; isopropyl alcohol at 30 - 60℃; for 3.75h; Product distribution / selectivity; | |
In acetone at 30 - 55℃; for 2.5h; Product distribution / selectivity; | |
In ethanol; chloroform at 55℃; | |
In chloroform at 50 - 55℃; for 0.5h; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
A
(3R)‐3‐(carbamoylmethyl)‐5‐methylhexanoic acid
B
(S)‑3‑carbamoylmethyl‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
With (R)-1-phenyl-ethyl-amine Resolution of racemate; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(S)‑3‑carbamoylmethyl‑5‑methylhexanoic acid
Conditions | Yield |
---|---|
Stage #1: (±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid With (S)-1-phenyl-ethylamine In ethanol; chloroform for 0.75h; Reflux; Stage #2: With hydrogenchloride In ethanol; chloroform; water for 0.75h; Cooling; | 16 g |
Multi-step reaction with 2 steps 1: chloroform / 1.5 h / 55 °C 2: hydrogenchloride / water / pH 1 - 2 View Scheme |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(S)-Mandelic acid
(S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (S)-mandelate
Conditions | Yield |
---|---|
Stage #1: (±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid With bromine; sodium hydroxide In water at 5 - 50℃; Hofmann Reaction; Stage #2: (S)-Mandelic acid With hydrogenchloride In water at 20 - 22℃; pH=4.5 - 5.5; Heating; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
1-phenylpropylamine
R-(-)-3-(carbamoylmethyl)-5-methylhexanoic acid 1-phenylpropylamine salt
Conditions | Yield |
---|---|
In ethanol; chloroform at 60 - 63℃; for 0.75h; |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(R)-1-phenyl-ethyl-amine
Conditions | Yield |
---|---|
In chloroform at 52.5℃; for 0.916667h; | 367 g |
(±)‑3‑(carbamoylmethyl)‑5‑methylhexanoic acid
(-)-menthol
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; Overall yield = 87.8 %; | A 1.436 g B 1.416 g |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View