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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Now we would like to update our product list for you, kindly check the below information: 1. Catalyst series ( such as Noble Metal Catalyst, Phosphorous ligand, etc ) 2. Pharmaceutical Intermediate ( such as diabtes series, Anti

1826-12-6

Cas:1826-12-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 1826-12-6 with competitive price

Cas:1826-12-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Thiazole, 4-phenyl-

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Other

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-phenyl-1,3-thiazole Cas no.1826-12-6 98%

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-Phenylthiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

4-Phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

4-phenyl-1,3-thiazole cas 1826-12-6Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

4-phenyl-1,3-thiazole cas 1826-12-6

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Other

inquiry

SAGECHEM LIMITED

1826-12-6 Application:intermediate

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Phenyl-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Other

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

4-phenylthiazole

Cas:1826-12-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

Best price/ 4-Phenyl-1,3-thiazole CAS NO.1826-12-6

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Nanjing Norris Pharm Technology Co., Ltd.

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

4-Phenyl-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Run-Biotech Co., Ltd.

Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 4-phenyl-1,3-thiazole, CAS:1826-12-6 with the most competitive price and the best qua

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Haiqiang Chemical Co.,Ltd.

ProName: 4-phenyl-1,3-thiazole CasNo: 1826-12-6 Application: It is an important raw material and in... DeliveryTime: prompt PackAge: according to the clients requirement Port: Shanghai Purity: 98%

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Jinan Great Chemical Co.,Ltd.

Application:Pharmaceutical intermediates

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beyond Pharmaceutical Co., Ltd

Used in medicine Application:Used in medicine

4-phenylthiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

4-phenyl-1,3-thiazole

Cas:1826-12-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-bromo-4-phenyl-1,3-thiazole
57516-16-2

2-bromo-4-phenyl-1,3-thiazole

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine In tetrahydrofuran at 20℃; for 3h; Reagent/catalyst; Time; Inert atmosphere;95%
With sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine In tetrahydrofuran at 25℃; for 3h; Inert atmosphere;95%
Multi-step reaction with 3 steps
1: N-chloro-succinimide / acetonitrile / 31 h / 20 °C / Inert atmosphere; Reflux
2: palladium diacetate; triphenylphosphine; N,N,N,N,-tetramethylethylenediamine; sodium tetrahydroborate / tetrahydrofuran / 9 h / 20 °C / Inert atmosphere
3: N,N,N,N,-tetramethylethylenediamine; sodium tetrahydroborate; PdCl2(1,1′-bis(di-tertbutylphosphino)ferrocene) / tetrahydrofuran / 20 h / 65 °C / Inert atmosphere
View Scheme
5-chloro-4-phenylthiazole
1403935-14-7

5-chloro-4-phenylthiazole

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; PdCl2(1,1′-bis(di-tertbutylphosphino)ferrocene) In tetrahydrofuran at 65℃; for 20h; Reagent/catalyst; Time; Temperature; Inert atmosphere;95%
With sodium tetrahydroborate; dichloro[1,1′-bis[bis(1,1-dimethylethyl)phosphino]ferrocene-P,P′]palladium; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 65℃; for 20h; Reagent/catalyst; Temperature; Inert atmosphere;95%
C22H17NOS

C22H17NOS

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With caesium carbonate In m-xylene at 150℃; for 40h; regioselective reaction;95%
2-chloro-4-phenylthiazole
1826-23-9

2-chloro-4-phenylthiazole

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 25℃; for 20h; Reagent/catalyst; Temperature; Inert atmosphere;93%
With sodium tetrahydroborate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 20℃; for 22h; Reagent/catalyst; Time; Inert atmosphere;92%
2,5-dibromo-4-phenylthiazole
188585-15-1

2,5-dibromo-4-phenylthiazole

A

5-bromo-4-phenylthiazole
59278-68-1

5-bromo-4-phenylthiazole

B

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine In tetrahydrofuran at 0℃; for 14h; Reagent/catalyst; Time; Inert atmosphere; regioselective reaction;A 84%
B 6%
With sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine In tetrahydrofuran for 14h; Reagent/catalyst; Temperature; Inert atmosphere; Overall yield = 90 %; regioselective reaction;
4-bromo-1,3-thiazole
34259-99-9

4-bromo-1,3-thiazole

phenylboronic acid
98-80-6

phenylboronic acid

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 100℃; for 18h; Suzuki Coupling; Inert atmosphere; Sealed tube;62%
2-Amino-4-phenylthiazole
2010-06-2

2-Amino-4-phenylthiazole

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With tetrahydrofuran; oxygen; nitrogen(II) oxide for 8h; Ambient temperature;40%
With copper(I) oxide; sulfuric acid; hypophosphorous acid; sodium nitrite 1.) 0 deg C, 2.) H2O, from -5 deg C to RT; Yield given. Multistep reaction;
Stage #1: 2-Amino-4-phenylthiazole With sulfuric acid; trifluoroacetic acid; sodium nitrite In water at -15℃; Sandmeyer Reaction;
Stage #2: With phosphoric acid In water at -15 - 20℃;
1,3-thiazole
288-47-1

1,3-thiazole

2-methylmercapto-4-phenylthiazole
2103-86-8

2-methylmercapto-4-phenylthiazole

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

2-methylthio-1,3-thiazole
5053-24-7

2-methylthio-1,3-thiazole

Conditions
ConditionsYield
With carbonylhydridetris(triphenylphosphine)rhodium(I); 1,3-bis(dicyclohexylphosphine)propane In 1,2-dichloro-benzene for 3h; Reflux; Inert atmosphere;A 31%
B 12%
ethyl acrylate
140-88-5

ethyl acrylate

2-bromo-4-phenyl-1,3-thiazole
57516-16-2

2-bromo-4-phenyl-1,3-thiazole

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

4,4'-diphenyl-2,2'-bithiazole
4072-63-3

4,4'-diphenyl-2,2'-bithiazole

C

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylic acid ethyl ester
111600-96-5

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine; palladium diacetate In N,N-dimethyl-formamide at 130℃; for 24h; sealed tube;A 22%
B 6%
C 19%
2-bromo-4-phenyl-1,3-thiazole
57516-16-2

2-bromo-4-phenyl-1,3-thiazole

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

4,4'-diphenyl-2,2'-bithiazole
4072-63-3

4,4'-diphenyl-2,2'-bithiazole

C

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylic acid ethyl ester
111600-96-5

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine; ethyl acrylate; palladium diacetate In N,N-dimethyl-formamide at 130℃; for 24h; sealed tube;A 22%
B 6%
C 19%
4-deuterio-5-phenylisothiazole
284680-73-5

4-deuterio-5-phenylisothiazole

A

5-phenylthiazole
1826-13-7

5-phenylthiazole

B

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

C

3-phenylisothiazole
10514-34-8

3-phenylisothiazole

Conditions
ConditionsYield
In benzene for 0.5h; phototransposition; Irradiation;A 19%
B 8%
C 9%
3-phenylisothiazole
10514-34-8

3-phenylisothiazole

A

2-phenylthiazole
1826-11-5

2-phenylthiazole

B

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
In methanol for 3h; phototransposition; Irradiation;A 4.9%
B 16.8%
acrylonitrile
107-13-1

acrylonitrile

2-bromo-4-phenyl-1,3-thiazole
57516-16-2

2-bromo-4-phenyl-1,3-thiazole

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

4,4'-diphenyl-2,2'-bithiazole
4072-63-3

4,4'-diphenyl-2,2'-bithiazole

C

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylonitrile
111600-97-6, 111600-98-7

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylonitrile

Conditions
ConditionsYield
With triethylamine; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 48h; sealed tube;A 12%
B 15%
C 15%
2-bromo-4-phenyl-1,3-thiazole
57516-16-2

2-bromo-4-phenyl-1,3-thiazole

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

4,4'-diphenyl-2,2'-bithiazole
4072-63-3

4,4'-diphenyl-2,2'-bithiazole

C

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylonitrile
111600-97-6, 111600-98-7

(E)-3-(4-Phenyl-thiazol-2-yl)-acrylonitrile

Conditions
ConditionsYield
With triethylamine; acrylonitrile; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 48h; sealed tube;A 12%
B 15%
C 15%
5-phenylisothiazole
1075-21-4

5-phenylisothiazole

A

5-phenylthiazole
1826-13-7

5-phenylthiazole

B

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

C

3-phenylisothiazole
10514-34-8

3-phenylisothiazole

Conditions
ConditionsYield
With TEA In benzene for 0.5h; Product distribution; Further Variations:; Reagents; Solvents; phototransposition; Irradiation;A 14%
B 2%
C 5%
styrene
292638-84-7

styrene

2-bromo-4-phenyl-1,3-thiazole
57516-16-2

2-bromo-4-phenyl-1,3-thiazole

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

4-phenyl-2-styrylthiazole
111600-99-8

4-phenyl-2-styrylthiazole

Conditions
ConditionsYield
With triethylamine; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 48h; sealed tube;A 7%
B 5%
4-phenylthiazole-2-carboxylic acid
59020-44-9

4-phenylthiazole-2-carboxylic acid

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

(4-phenyl-thiazol-2-yl)hydrazine hydrochloride
17574-10-6

(4-phenyl-thiazol-2-yl)hydrazine hydrochloride

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With ethanol; mercury(II) oxide
1-chloroacetophenone
532-27-4

1-chloroacetophenone

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With piperidine; tetraphosphorus decasulfide
1,3-thiazole
288-47-1

1,3-thiazole

A

5-phenylthiazole
1826-13-7

5-phenylthiazole

B

2-phenylthiazole
1826-11-5

2-phenylthiazole

C

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With dibenzoyl peroxide Further byproducts given;
2-phenylthiazole
1826-11-5

2-phenylthiazole

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

3-phenylisothiazole
10514-34-8

3-phenylisothiazole

Conditions
ConditionsYield
In ethanol Heating;
In ethanol Irradiation;
5-phenyl-2,3-dihydro-thiazolo[2,3-b]thiazolylium; bromide
6094-68-4

5-phenyl-2,3-dihydro-thiazolo[2,3-b]thiazolylium; bromide

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With sodium thiophenolate In methanol for 1h; Heating;
formaldehyd
50-00-0

formaldehyd

α-bromoacetophenone
70-11-1

α-bromoacetophenone

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
(i) P2S5, dioxane, (ii) /BRN= 606474/; Multistep reaction;
2-phenylthiazole
1826-11-5

2-phenylthiazole

A

5-phenylisothiazole
1075-21-4

5-phenylisothiazole

B

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

C

3-phenylisothiazole
10514-34-8

3-phenylisothiazole

Conditions
ConditionsYield
In benzene for 7h; Product distribution; Mechanism; Irradiation; other phenylthiazoles and phenylisothiazoles; phototransposition and photodeuteration;A n/a
B 26 % Chromat.
C 7 % Chromat.
N-(1-phenylethylidene)methanamine
6907-71-7

N-(1-phenylethylidene)methanamine

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With sulfur dioxide; soda-lime; zirconium(IV) oxide at 450℃;26 % Spectr.
4-Phenyl-isothiazole
936-46-9

4-Phenyl-isothiazole

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With TEA In methanol for 0.5h; Irradiation;82 % Chromat.
With TEA In cyclohexane Product distribution; Quantum yield; Irradiation; other solvents, bases; photochemistry of 4-substituted isothiazoles; effect of reaction conditions; trapping of intermediate species; mechanism; sensitized irradiation;
2-nitrosoimino-4-phenyl-thiazoline

2-nitrosoimino-4-phenyl-thiazoline

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
With ethanol
4-phenylthiazole-2(3H)-thione
2103-88-0

4-phenylthiazole-2(3H)-thione

ammonia
7664-41-7

ammonia

Raney nickel

Raney nickel

A

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

B

acetophenone
98-86-2

acetophenone

2-bromo-5-chloro-4-phenylthiazole
1403935-16-9

2-bromo-5-chloro-4-phenylthiazole

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: palladium diacetate; triphenylphosphine; N,N,N,N,-tetramethylethylenediamine; sodium tetrahydroborate / tetrahydrofuran / 9 h / 20 °C / Inert atmosphere
2: N,N,N,N,-tetramethylethylenediamine; sodium tetrahydroborate; PdCl2(1,1′-bis(di-tertbutylphosphino)ferrocene) / tetrahydrofuran / 20 h / 65 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine / tetrahydrofuran / 9 h / 25 °C / Inert atmosphere
2: sodium tetrahydroborate; dichloro[1,1′-bis[bis(1,1-dimethylethyl)phosphino]ferrocene-P,P′]palladium; N,N,N,N,-tetramethylethylenediamine / tetrahydrofuran / 20 h / 65 °C / Inert atmosphere
View Scheme
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

Bis(trimethylsilyl)ethyne
14630-40-1

Bis(trimethylsilyl)ethyne

3,4-bis(trimethylsilyl)thiophene
156642-32-9

3,4-bis(trimethylsilyl)thiophene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 325℃; for 144h;92%
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 325℃; for 144h;92 % Turnov.
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

diphenyl acetylene
501-65-5

diphenyl acetylene

3,4-diphenylthiophene
16939-13-2

3,4-diphenylthiophene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 325 - 340℃;83%
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 340℃; for 60h;83 % Turnov.
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

1,2-(methylenedioxy)-4-bromobenzene
2635-13-4

1,2-(methylenedioxy)-4-bromobenzene

C16H11NO2S

C16H11NO2S

Conditions
ConditionsYield
With bis(tri-tert-butylphosphine)palladium(0); lithium tert-butoxide In 1,4-dioxane at 80℃; for 48h; regioselective reaction;78%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

bromobenzene
108-86-1

bromobenzene

2,4-diphenylthiazole
1826-14-8

2,4-diphenylthiazole

Conditions
ConditionsYield
With bis(tri-tert-butylphosphine)palladium(0); lithium tert-butoxide In 1,4-dioxane at 80℃; for 48h; regioselective reaction;77%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

iodobenzene
591-50-4

iodobenzene

4,5-diphenylthiazole
1826-15-9

4,5-diphenylthiazole

Conditions
ConditionsYield
With tert-Amyl alcohol; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate at 80℃; for 36h; regioselective reaction;77%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

para-iodoanisole
696-62-8

para-iodoanisole

5-(4-methoxyphenyl)-4-phenylthiazole
1384515-65-4

5-(4-methoxyphenyl)-4-phenylthiazole

Conditions
ConditionsYield
With tert-Amyl alcohol; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate at 80℃; for 36h; regioselective reaction;75%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

2-methylthio-1,3-thiazole
5053-24-7

2-methylthio-1,3-thiazole

A

2-methylmercapto-4-phenylthiazole
2103-86-8

2-methylmercapto-4-phenylthiazole

B

2,5-di(methylthio)thiazole

2,5-di(methylthio)thiazole

Conditions
ConditionsYield
With carbonylhydridetris(triphenylphosphine)rhodium(I); 1,3-bis(dicyclohexylphosphine)propane In 1,2-dichloro-benzene for 3h; Inert atmosphere; Reflux;A 74%
B 10%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

1-(trimethylsilyl)-1-hexyne
3844-94-8

1-(trimethylsilyl)-1-hexyne

3-n-butyl-4-(trimethylsilyl)thiophene

3-n-butyl-4-(trimethylsilyl)thiophene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 325 - 340℃;73%
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 330℃; for 168h;73 % Turnov.
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

1,12-diiodododecane
24772-65-4

1,12-diiodododecane

C30H38N2S2(2+)*2I(1-)

C30H38N2S2(2+)*2I(1-)

Conditions
ConditionsYield
In acetonitrile for 72h; Heating;72%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

5-bromo-1,3-xylene
556-96-7

5-bromo-1,3-xylene

C17H15NS

C17H15NS

Conditions
ConditionsYield
With bis(tri-tert-butylphosphine)palladium(0); lithium tert-butoxide In 1,4-dioxane at 100℃; for 48h; regioselective reaction;72%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

4-tolyl iodide
624-31-7

4-tolyl iodide

5-(4-methylphenyl)-4-phenylthiazole
1384515-66-5

5-(4-methylphenyl)-4-phenylthiazole

Conditions
ConditionsYield
With tert-Amyl alcohol; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate at 80℃; for 36h; regioselective reaction;69%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

2-Bromo-6-methoxynaphthalene
5111-65-9

2-Bromo-6-methoxynaphthalene

C20H15NOS

C20H15NOS

Conditions
ConditionsYield
With bis(tri-tert-butylphosphine)palladium(0); lithium tert-butoxide In 1,4-dioxane at 100℃; for 48h; regioselective reaction;68%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

1-Chloro-4-iodobenzene
637-87-6

1-Chloro-4-iodobenzene

C15H10ClNS

C15H10ClNS

Conditions
ConditionsYield
With tert-Amyl alcohol; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate at 80℃; for 36h; regioselective reaction;66%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

3-(trimethylsilyl)thiophene
18245-17-5

3-(trimethylsilyl)thiophene

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 325 - 340℃;65%
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 340℃; for 48h;65 % Turnov.
2-bromo-5-methyl thiophene
765-58-2

2-bromo-5-methyl thiophene

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

C14H11NS2

C14H11NS2

Conditions
ConditionsYield
With bis(tri-tert-butylphosphine)palladium(0); lithium tert-butoxide In 1,4-dioxane at 80℃; for 48h; regioselective reaction;62%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

diphenyl acetylene
501-65-5

diphenyl acetylene

(E)-5-(1,2-diphenylvinyl)-4-phenylthiazole

(E)-5-(1,2-diphenylvinyl)-4-phenylthiazole

Conditions
ConditionsYield
With acetic acid; bis(dibenzylideneacetone)-palladium(0); tricyclohexylphosphine In N,N-dimethyl acetamide at 130℃; for 14h; Inert atmosphere; Glovebox; stereoselective reaction;61%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

1-bromo-3,4,5-trimethoxybenzene
2675-79-8

1-bromo-3,4,5-trimethoxybenzene

4-phenyl-5-(3,4,5-trimethoxyphenyl)thiazole
1384515-68-7

4-phenyl-5-(3,4,5-trimethoxyphenyl)thiazole

Conditions
ConditionsYield
With tert-Amyl alcohol; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate at 100℃; for 18h; regioselective reaction;60%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

4-Iodobenzotrifluoride
455-13-0

4-Iodobenzotrifluoride

C16H10F3NS

C16H10F3NS

Conditions
ConditionsYield
With tert-Amyl alcohol; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate at 80℃; for 36h; regioselective reaction;59%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

acrylic acid n-butyl ester
141-32-2

acrylic acid n-butyl ester

(E)-butyl 3-(4-phenylthiazol-5-yl)acrylate

(E)-butyl 3-(4-phenylthiazol-5-yl)acrylate

Conditions
ConditionsYield
With 5-Nitro-1,10-phenanthroline; copper diacetate; palladium diacetate; caesium carbonate; dimethyl sulfoxide In tert-Amyl alcohol at 100℃; for 12h; Inert atmosphere; regioselective reaction;55%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

methyl 4-iodobenzoate
619-44-3

methyl 4-iodobenzoate

C17H13NO2S

C17H13NO2S

Conditions
ConditionsYield
With tert-Amyl alcohol; di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; caesium carbonate at 100℃; for 18h; regioselective reaction;49%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

iodobenzene
591-50-4

iodobenzene

4-phenyl-2-phenylselenothiazole

4-phenyl-2-phenylselenothiazole

Conditions
ConditionsYield
With selenium; potassium carbonate; copper dichloride In N,N-dimethyl-formamide at 150℃; for 24h; Schlenk technique; Inert atmosphere;40%
4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

2-methylmercaptobenzothiazole
615-22-5

2-methylmercaptobenzothiazole

2-methylmercapto-4-phenylthiazole
2103-86-8

2-methylmercapto-4-phenylthiazole

Conditions
ConditionsYield
With carbonylhydridetris(triphenylphosphine)rhodium(I); 1,3-bis(dicyclohexylphosphine)propane In chlorobenzene for 3h; Reflux; Inert atmosphere;36%
4-bromo-1-methyl-1H-pyrazole
15803-02-8

4-bromo-1-methyl-1H-pyrazole

4-phenyl-thiazole
1826-12-6

4-phenyl-thiazole

bicyclo[2.2.1]hepta-2,5-diene
121-46-0

bicyclo[2.2.1]hepta-2,5-diene

2-(cis-3-(1-methyl-1H-pyrazol-4-yl)bicyclo[2.2.1]hept-5-en-2-yl)-4-phenylthiazole

2-(cis-3-(1-methyl-1H-pyrazol-4-yl)bicyclo[2.2.1]hept-5-en-2-yl)-4-phenylthiazole

Conditions
ConditionsYield
With copper(l) iodide; palladium diacetate; caesium carbonate; bis[2-(diphenylphosphino)phenyl] ether In 1,4-dioxane at 130℃; for 16h; Glovebox; Inert atmosphere;36%

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