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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

Methyl 2-hydroxyisobutyrate TOP1 supplier in China

Cas:2110-78-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Methyl 2-hydroxy-2-methylpropionate

Cas:2110-78-3

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA. Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients

Hot Sale Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Methyl 2-hydroxyisobutyrate Basic information Product Name: Methyl 2-hydroxyisobutyrate Synonyms: 2-hydroxy-2-methyl-propanoicacimethylester;2-hydroxyisobutyricacidmethylester(alpha-);La

Methyl 2-hydroxyisobutyrate 2110-78-3

Cas:2110-78-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 2110-78-3 with best price

Cas:2110-78-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Propanoic acid,2-hydroxy-2-methyl-, methyl ester 2110-78-3

Cas:2110-78-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Ocean Chemical Co., Ltd.

1.High purity, like 99%, 99.9%, 99.95%, 99.99%, 99.999% 2.Quality control, test sample before shipping and keep sample for 3 years after shipping; 3. Prompt shipment with professional documents; 4. Packing as your request, with photo before s

Methyl 2-Hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1)

Methyl 2-Hydroxyisobutyrate (CAS#: 2110-78-3).

Cas:2110-78-3

Min.Order:1 Gram

FOB Price: $1.0 / 5.0

Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad.

Methyl 2-hydroxyisobutyrate Ingredients

Cas:2110-78-3

Min.Order:1 Kilogram

FOB Price: $60.0 / 70.0

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Propanoic acid,2-hydroxy-2-methyl-, methyl ester

Cas:2110-78-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2110-78-3

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

HBM(Hydroxyisobutyric Acid Methyl Ester)

Cas:2110-78-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Specif

Methyl 2-hydroxyisobutyrate CAS 2110-78-3

Cas:2110-78-3

Min.Order:1 Kilogram

FOB Price: $75.0 / 150.0

Type:Trading Company

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Hangzhou Lingrui Chemical Co.,Ltd.

methyl 2-hydroxy-2-methylpropanoateAppearance:white powder Storage:In Shade Package:according to customers' requirements Application:pharmaceutical intermediate Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect.

methyl 2-hydroxy-2-methylpropanoate

Cas:2110-78-3

Min.Order:1 Gram

Negotiable

Type:Other

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Methyl 2-hydroxyisobutyrate CAS 2110-78-3 In stock HBM 2-Hydroxy Isobutyric acid Methyl Ester

Cas:2110-78-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Product Name:Methyl 2-hydroxyisobutyrate CAS No:211

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Methyl2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: Methyl 2-hydroxyisobutyrate Synonyms: Methyl 2-methyllactate CAS: 2110-78-3 MF: C5H10O3 Appearance: Colorless liquid Storage:Preserve in well-closed, light-resistant and airtight containers. Package:25kg/drum Application:Pharmaceutical Inter

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-Hydroxyisobutyric acid methyl ester

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Manufacturers

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Methyl 2-hydroxyisobutyrate

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

High quality Methyl 2-hydroxyisobutyrate cas NO.: 2110-78-3

Cas:2110-78-3

Min.Order:0

Negotiable

Type:Other

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Synthetic route

methanol
67-56-1

methanol

2-hydroxyisobutyramide
13027-88-8

2-hydroxyisobutyramide

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
zirconium(IV) oxide at 190℃; under 759.826 Torr; for 24h; Product distribution / selectivity;95%
With yttria-stabilized zirconia at 220℃; under 45004.5 Torr; Catalytic behavior; Concentration; Reagent/catalyst; Temperature;34.9%
With lead(IV) tetraacetate at 200℃; for 1h; in a sealed ampul;31%
methanol
67-56-1

methanol

2-methyllactic acid
594-61-6

2-methyllactic acid

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
With 4-(dihydroxyboranyl)-1-methylpyridin-1-ium iodide for 15h; Heating;92%
With zinc(II) chloride at 60℃; for 6h; sealed tube;83%
With thionyl chloride81%
methanol
67-56-1

methanol

2-methyl-2-sulphatopropionamide
49562-37-0

2-methyl-2-sulphatopropionamide

2-hydroxyisobutyramide
13027-88-8

2-hydroxyisobutyramide

A

2-methyllactic acid
594-61-6

2-methyllactic acid

B

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
With water; acetic acid at 115℃; under 1875.19 Torr; for 1h; Product distribution / selectivity;A 19.2%
B 81.5%
1-methoxy-2-methyl-1-trimethylsiloxy-1-propene
31469-15-5

1-methoxy-2-methyl-1-trimethylsiloxy-1-propene

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
Stage #1: 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene With pyridine; methyltrioxorhenium(VII) In acetic acid; acetonitrile at 0 - 20℃; Oxidation;
Stage #2: With potassium fluoride In methanol for 1h; Substitution; Further stages.;
71%
With 3-chloro-benzenecarboperoxoic acid 1.) hexane, RT, 30 min, 2.) Et3NF, 30 min; Yield given. Multistep reaction;
Methyl isobutyrate
547-63-7

Methyl isobutyrate

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
With oxygen In N,N-dimethyl-formamide at 20℃; electrolysis;40%
With tert.-butylhydroperoxide at 150℃;
Multi-step reaction with 2 steps
1: 83 percent / 1.) LDA / 1.) THF, -78 deg C, 10 min, 2.) -> RT, 3 h
2: MCPBA / 1.) hexane, RT, 30 min, 2.) Et3NF, 30 min
View Scheme
methanol
67-56-1

methanol

5,5-dimethyl-2-oxo-2λ4-[1,3,2]dioxathiolan-4-one
2852-00-8

5,5-dimethyl-2-oxo-2λ4-[1,3,2]dioxathiolan-4-one

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methanol
67-56-1

methanol

2-hydroxy-2-methylpropanenitrile
75-86-5

2-hydroxy-2-methylpropanenitrile

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
With sulfuric acid; hydroquinone Zugeben von trocknem Na2SO4 und Destillieren bis auf 225-240grad;
With sulfuric acid; hydroquinone Zugeben von trocknem Na2SO4 und Destillieren bis auf 225-240grad;
2,2,6,6-tetramethyl-4-oxo-3,5-dioxa-heptanedioic acid dimethyl ester

2,2,6,6-tetramethyl-4-oxo-3,5-dioxa-heptanedioic acid dimethyl ester

acetone
67-64-1

acetone

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

Conditions
ConditionsYield
at 445 - 455℃; durch ein mit Quarzstuecken gefuelltes erhitztes Eisenrohr;
at 445 - 455℃; durch ein mit Quarzstuecken gefuelltes erhitztes Eisenrohr;
methanol
67-56-1

methanol

Isopropenyl acetate
108-22-5

Isopropenyl acetate

carbon monoxide
201230-82-2

carbon monoxide

A

2-methoxy-2,5,5-trimethyl-1,3-dioxolan-4-one
57865-41-5

2-methoxy-2,5,5-trimethyl-1,3-dioxolan-4-one

B

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

C

methyl 3-acetoxybutyrate
89422-42-4

methyl 3-acetoxybutyrate

D

methyl 2-acetoxy-2-methylpropionate
57865-37-9

methyl 2-acetoxy-2-methylpropionate

Conditions
ConditionsYield
With 2,6-dimethylpyridine; PdCl2(PPh)3 In benzene at 100℃; under 152000 Torr; for 5.5h; Product distribution; Mechanism; other reagents, var. educts ratio, temp., pressure and time;
With bis-triphenylphosphine-palladium(II) chloride In benzene at 100℃; under 114000 Torr; for 5h; Product distribution; Mechanism; other acetates, var. Pd and pyridine derivs. as reagents, concns. of reagents, temp. ans reaction time;A 13 % Chromat.
B 5.7 % Chromat.
C 1.3 % Chromat.
D 1.2 % Chromat.
methanol
67-56-1

methanol

2-hydroxyisobutyramide
13027-88-8

2-hydroxyisobutyramide

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

α-methoxyisobutyramide
82473-56-1

α-methoxyisobutyramide

Conditions
ConditionsYield
With lead(IV) tetraacetate at 200℃; under 22501.8 - 30002.4 Torr; Product distribution; Rate constant; molar ratio of lead acetate; time;;
methanol
67-56-1

methanol

2-hydroxy-2-methylpropanenitrile
75-86-5

2-hydroxy-2-methylpropanenitrile

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

2-Hydroxy-2-methyl-thiopropionic acid O-methyl ester
99668-31-2

2-Hydroxy-2-methyl-thiopropionic acid O-methyl ester

Conditions
ConditionsYield
With hydrogenchloride; hydrogen sulfide 1.) ether, RT, 16 h, 2.) ether, RT, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
methanol
67-56-1

methanol

2-hydroxy-2-methylpropanenitrile
75-86-5

2-hydroxy-2-methylpropanenitrile

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

2-Hydroxy-2-methyl-propionimidic acid methyl ester
99668-30-1

2-Hydroxy-2-methyl-propionimidic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether for 16h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
methyl 2-methyl-2-((methanesulfonyl)oxy)propanoate
91190-29-3

methyl 2-methyl-2-((methanesulfonyl)oxy)propanoate

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

Conditions
ConditionsYield
With 1,1,1,3',3',3'-hexafluoro-propanol; lutidine In water Yield given. Yields of byproduct given;
With 2,6-dimethylpyridine; 1,1,1,3',3',3'-hexafluoro-propanol In water at 90℃; Rate constant; Kinetics; Thermodynamic data; ΔH++, ΔS++;
hydrogenchloride
7647-01-0

hydrogenchloride

methyl 2-aminoisobutyrate hydrochloride
15028-41-8

methyl 2-aminoisobutyrate hydrochloride

sodium nitrite

sodium nitrite

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

2-methoxy-2-methylpropanoic acid
13836-62-9

2-methoxy-2-methylpropanoic acid

C

methacrylic acid methyl ester
80-62-6

methacrylic acid methyl ester

Conditions
ConditionsYield
at 0℃; nachfolgendem Aufbewahren;
C7H9(2)H6O3S(1+)*CF3O3S(1-)

C7H9(2)H6O3S(1+)*CF3O3S(1-)

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
In dimethylsulfoxide-d6 at 80℃;
2-hydroxyisobutyramide
13027-88-8

2-hydroxyisobutyramide

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
titanium(IV) isopropylate; methanol
titanium(IV) isopropylate; methanol
titanium tetraisopropoxide (Ti(O-isoPr)4)

titanium tetraisopropoxide (Ti(O-isoPr)4)

2-hydroxyisobutyramide
13027-88-8

2-hydroxyisobutyramide

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
In methanol
2-hydroxy-2-methylpropanenitrile
75-86-5

2-hydroxy-2-methylpropanenitrile

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

natrium(1+)*cobalt(III)((NCOC(CH3)2O)26H4)(1-)*(CH3)2CO

natrium(1+)*cobalt(III)((NCOC(CH3)2O)26H4)(1-)*(CH3)2CO

A

1,3-dihydro-2H-benzimidazol-2-one
615-16-7

1,3-dihydro-2H-benzimidazol-2-one

B

(C6H4)(NHCOC(CH3)2OH)2

(C6H4)(NHCOC(CH3)2OH)2

C

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

D

cobalt(II)

cobalt(II)

E

acetone
67-64-1

acetone

Conditions
ConditionsYield
With methanol In methanol Irradiation (UV/VIS); irradiation of Co-complex (450-W medium-pressure Hg lamp, 366 nm); analyzing of Co(2+) by adding of KSCN (UV), other products are detected by HPLC or GC-Ms;
methanol
67-56-1

methanol

Methyl formate
107-31-3

Methyl formate

2-hydroxyisobutyramide
13027-88-8

2-hydroxyisobutyramide

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

Conditions
ConditionsYield
sodium amide; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 120℃; Product distribution / selectivity;
methanol
67-56-1

methanol

2-methyllactic acid
594-61-6

2-methyllactic acid

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

2-amino-2-cyanopropane
19355-69-2

2-amino-2-cyanopropane

Conditions
ConditionsYield
With zirconium dioxide yttrium-doped at 220℃; under 300.03 Torr; Catalytic behavior; Temperature; Reagent/catalyst; Gas phase; Autoclave;
methanol
67-56-1

methanol

2-methyllactic acid
594-61-6

2-methyllactic acid

A

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

B

acetone
67-64-1

acetone

C

2-amino-2-cyanopropane
19355-69-2

2-amino-2-cyanopropane

Conditions
ConditionsYield
With zirconium dioxide yttrium-doped at 220℃; under 300.03 Torr; Gas phase; Autoclave;
N-[4-(3-hydroxy-3-methylbut-1-ynl)-2-isopropylphenyl]acetamide

N-[4-(3-hydroxy-3-methylbut-1-ynl)-2-isopropylphenyl]acetamide

A

2-methyllactic acid
594-61-6

2-methyllactic acid

B

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

C

4-amino-3-isopropylbenzoic acid
51688-76-7

4-amino-3-isopropylbenzoic acid

D

methyl 4-acetamido-3-isopropylbenzoate

methyl 4-acetamido-3-isopropylbenzoate

E

N-(4-carboxy-2-isopropylphenyl)acetamide

N-(4-carboxy-2-isopropylphenyl)acetamide

F

methyl 4-amino-3-(propan-2-yl)benzoate

methyl 4-amino-3-(propan-2-yl)benzoate

Conditions
ConditionsYield
With ozone In methanol
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

allyl bromide
106-95-6

allyl bromide

methyl 2-(allyloxy)-2-methylpropanoate
17859-94-8

methyl 2-(allyloxy)-2-methylpropanoate

Conditions
ConditionsYield
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride In N,N-dimethyl-formamide; mineral oil Cooling with ice;
Stage #2: allyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; Cooling with ice;
100%
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h;
Stage #2: allyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 18h;
85.88%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 16h;30%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

2-methyl-2-[((dimethyl)-(1,1-dimethylethyl)silyl)oxy]-propanoate
128246-08-2

2-methyl-2-[((dimethyl)-(1,1-dimethylethyl)silyl)oxy]-propanoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;97%
2-mercapto-5-nitropyridine
2127-09-5

2-mercapto-5-nitropyridine

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl 2-methyl-2-[(5-nitropyridin-2-yl)sulfanyl]propionate

methyl 2-methyl-2-[(5-nitropyridin-2-yl)sulfanyl]propionate

Conditions
ConditionsYield
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h; Inert atmosphere;97%
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h;97%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

N-hydroxy-3-(hydroxyiminomethyl)benzamidine
1256486-34-6

N-hydroxy-3-(hydroxyiminomethyl)benzamidine

3-[5-(1-hydroxy-1-methylethyl)-[1,2,4]oxadiazol-3-yl]benzaldehyde oxime
1286182-73-7

3-[5-(1-hydroxy-1-methylethyl)-[1,2,4]oxadiazol-3-yl]benzaldehyde oxime

Conditions
ConditionsYield
Stage #1: methyl 2-hydroxy-2-methylpropionate; N-hydroxy-3-(hydroxyiminomethyl)benzamidine In 1-methyl-pyrrolidin-2-one at 22 - 27℃; Inert atmosphere;
Stage #2: With sodium methylate In 1-methyl-pyrrolidin-2-one; methanol at 25 - 30℃;
95.6%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

chloro-diphenylphosphine
1079-66-9

chloro-diphenylphosphine

methyl 2-[(diphenylphosphino)oxy]-2-methylpropionate
857665-53-3

methyl 2-[(diphenylphosphino)oxy]-2-methylpropionate

Conditions
ConditionsYield
With dmap; triethylamine In tetrahydrofuran at 20℃; for 2h;95%
With dmap; triethylamine In tetrahydrofuran at 20℃; for 2h;
With triethylamine In dichloromethane at 20℃; for 2h; Inert atmosphere;
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

methyl 2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-methylpropionate
70204-06-7

methyl 2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-methylpropionate

Conditions
ConditionsYield
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h; Inert atmosphere;94%
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h;94%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

p-methoxybenzyl chloride
824-94-2

p-methoxybenzyl chloride

methyl 2-((4-methoxybenzyl)oxy)-2-methylpropanoate
19811-25-7

methyl 2-((4-methoxybenzyl)oxy)-2-methylpropanoate

Conditions
ConditionsYield
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 25℃; for 0.166667h; Schlenk technique; Inert atmosphere;
Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide; mineral oil at 25℃; for 12h; Schlenk technique; Inert atmosphere;
93%
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide for 0.0833333h;
Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide at 20 - 40℃; for 22h;
35%
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride In N,N-dimethyl-formamide Cooling with ice;
Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide at 20℃; for 2h;
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl iodide
74-88-4

methyl iodide

methyl 2-methoxy-2-methylpropanoate
17860-39-8

methyl 2-methoxy-2-methylpropanoate

Conditions
ConditionsYield
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 20℃;
93%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;93%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl iodide
74-88-4

methyl iodide

3-methoxy-2-methylpropenoic acid sodium

3-methoxy-2-methylpropenoic acid sodium

Conditions
ConditionsYield
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 20℃;
93%
Stage #1: methyl 2-hydroxy-2-methylpropionate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;
93%
triethylsilyl chloride
994-30-9

triethylsilyl chloride

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl 2-methyl-2-(triethylsiloxy)propanoate
102307-27-7

methyl 2-methyl-2-(triethylsiloxy)propanoate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; for 24h; Inert atmosphere;92%
With pyridine at 60℃;91%
With dmap; triethylamine In dichloromethane at 25℃; for 24h;
With dmap; triethylamine In dichloromethane at 20℃; for 24h; Inert atmosphere;
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

methyl 2-methyl-2-((methanesulfonyl)oxy)propanoate
91190-29-3

methyl 2-methyl-2-((methanesulfonyl)oxy)propanoate

Conditions
ConditionsYield
With triethylamine In dichloromethane -50 - -40 deg C -> 0 deg C;92%
With triethylamine In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; tert-butyl methyl ether
With triethylamine In tert-butyl methyl ether at -5 - 20℃; for 5h; Inert atmosphere;
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl 2-(trimethylsilyloxy)-2-methyl-propionate
162012-24-0

methyl 2-(trimethylsilyloxy)-2-methyl-propionate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; for 24h; Inert atmosphere;92%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

2-mercapto-6-nitrobenzothiazole
4845-58-3

2-mercapto-6-nitrobenzothiazole

methyl 2-methyl-2-[(6-nitro-1,3-benzothiazol-2-yl)sulfanyl]-propionate
1152091-97-8

methyl 2-methyl-2-[(6-nitro-1,3-benzothiazol-2-yl)sulfanyl]-propionate

Conditions
ConditionsYield
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h; Inert atmosphere;91%
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h;91%
diethyl phosphorylchloridite
589-57-1

diethyl phosphorylchloridite

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl 2-<(diethoxyphosphino)oxy>-2-methylpropanoate
118459-01-1

methyl 2-<(diethoxyphosphino)oxy>-2-methylpropanoate

Conditions
ConditionsYield
With pyridine In tetrahydrofuran at 0 - 20℃; for 1h;90%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2-methyl-2-[((dimethyl)-(1,1-dimethylethyl)silyl)oxy]-propanoate
128246-08-2

2-methyl-2-[((dimethyl)-(1,1-dimethylethyl)silyl)oxy]-propanoate

Conditions
ConditionsYield
With 1H-imidazole; dmap In N,N-dimethyl-formamide at 100℃; for 16h; Etherification;90%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 72h;90%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 48h; Inert atmosphere;70%
With 1H-imidazole In dichloromethane at 0 - 20℃; Inert atmosphere;
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

2-hydroxy-N-methoxy-N,2-dimethylpropanamide
1124273-99-9

2-hydroxy-N-methoxy-N,2-dimethylpropanamide

Conditions
ConditionsYield
With isopropylmagnesium chloride In tetrahydrofuran at -20 - 20℃; for 1.5h;90%
With isopropylmagnesium chloride In tetrahydrofuran at -20 - 0℃; for 1.5h; Inert atmosphere;80%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

carbonochloridic acid, chloromethyl ester
22128-62-7

carbonochloridic acid, chloromethyl ester

methyl 2-(((chloromethoxy)carbonyl)oxy)-2-methylpropanoate

methyl 2-(((chloromethoxy)carbonyl)oxy)-2-methylpropanoate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃; for 1.5h;90%
With pyridine In dichloromethane at 0 - 20℃; for 1.5h; Inert atmosphere;90%
With pyridine; hydrogenchloride In dichloromethane at 0 - 20℃; for 1.5h; Inert atmosphere;90%
With pyridine In dichloromethane at 0 - 20℃; for 2h;
diethyl phosphorylchloridite
589-57-1

diethyl phosphorylchloridite

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl 2-<(ethoxyphosphinyl)oxy>-2-methylpropanoate

methyl 2-<(ethoxyphosphinyl)oxy>-2-methylpropanoate

Conditions
ConditionsYield
With iron(III) chloride In hexane at 0 - 20℃;89%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

2-sulfanyl-1,3-benzoxazole
2382-96-9

2-sulfanyl-1,3-benzoxazole

methyl 2-[(1,3-benzoxazol-2-yl)sulfanyl]-2-methylpropionate

methyl 2-[(1,3-benzoxazol-2-yl)sulfanyl]-2-methylpropionate

Conditions
ConditionsYield
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h; Inert atmosphere;89%
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h;89%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

1-bromomethyl-4-iodobenzene
16004-15-2

1-bromomethyl-4-iodobenzene

2-[(4-iodobenzyl)oxy]-2-methylpropionic acid methyl ester
840503-21-1

2-[(4-iodobenzyl)oxy]-2-methylpropionic acid methyl ester

Conditions
ConditionsYield
With ammonium chloride In tetrahydrofuran; ethyl acetate; paraffin86%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

para-nitrobenzenethiol
1849-36-1

para-nitrobenzenethiol

methyl 2-methyl-2-[(4-nitrophenyl)sulfanyl]propionate

methyl 2-methyl-2-[(4-nitrophenyl)sulfanyl]propionate

Conditions
ConditionsYield
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h; Inert atmosphere;85%
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h;85%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

methyl 2-methyl-2-(tetrahydropyranyloxy)propanoate
131489-99-1

methyl 2-methyl-2-(tetrahydropyranyloxy)propanoate

Conditions
ConditionsYield
pyridin-2-yl tosylate In dichloromethane for 1.5h;85%
propanoic acid methyl ester
554-12-1

propanoic acid methyl ester

methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

4-hydroxy-3,5,5-trimethylfuran-2(5H)-one
81608-85-7

4-hydroxy-3,5,5-trimethylfuran-2(5H)-one

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 20℃; Dieckmann cyclization;85%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

thiophenol
108-98-5

thiophenol

methyl 2-methyl-2-(phenylsulfanyl)propionate
68734-79-2

methyl 2-methyl-2-(phenylsulfanyl)propionate

Conditions
ConditionsYield
With 2,6-Di-tert-butyl-1,4-benzoquinone; phenyl diphenylphosphinite In toluene at 40℃; for 24h; Inert atmosphere;83%
With 2,6-Di-tert-butyl-1,4-benzoquinone; phenyl diphenylphosphinite In toluene at 40℃; for 24h;83%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

1-methyl-5-mercaptotetrazole
13183-79-4

1-methyl-5-mercaptotetrazole

methyl 2-methyl-2-[(1-methyl-1H-tetrazol-5-yl)sulfanyl]-propionate
1152091-95-6

methyl 2-methyl-2-[(1-methyl-1H-tetrazol-5-yl)sulfanyl]-propionate

Conditions
ConditionsYield
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h; Inert atmosphere;83%
With ethyl-2-azidoacetate; phenyl diphenylphosphinite In toluene at 40℃; for 24h;83%
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

2-Methyl-1,2-propanediol
558-43-0

2-Methyl-1,2-propanediol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 1h;82.6%
Stage #1: methyl 2-hydroxy-2-methylpropionate With lithium aluminium tetrahydride In tetrahydrofuran at 20℃;
Stage #2: With water; sodium hydroxide In tetrahydrofuran
68%
With potassium tert-butylate; hydrogen; [tris(μ-chloro)bis((triphos)ruthenium(II))] chloride In methanol at 100℃; under 30003 Torr; for 13h; Inert atmosphere; Autoclave;90.4 %Chromat.
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 12.3333h;
methyl 2-hydroxy-2-methylpropionate
2110-78-3

methyl 2-hydroxy-2-methylpropionate

(2,4-dichlorophenyl)methanesulfonyl chloride
88691-50-3

(2,4-dichlorophenyl)methanesulfonyl chloride

methyl 2-{[(2,4-dichlorobenzyl)sulphonyl]oxy}-2-methylpropanoate
308851-22-1

methyl 2-{[(2,4-dichlorobenzyl)sulphonyl]oxy}-2-methylpropanoate

Conditions
ConditionsYield
Stage #1: methyl 2-hydroxy-2-methylpropionate With pyridine at 0℃;
Stage #2: (2,4-dichlorophenyl)methanesulfonyl chloride at 5℃; for 120h;
81.6%
With pyridine at 5℃; for 120h;81.6%

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