Products

Refine

Country

Business Type

Certificate

Display

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Specification : N-Benzylpiperidine-4-carboxaldehy

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name N-Benzylpiperidine-4-carboxaldehyde

1-Benzylpiperidine-4-carbaldehyde

Cas:22065-85-6

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-Benzyl-4-Piperidine Carboxaldehyde

Cas:22065-85-6

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-Benzyl-4-piperidinecarboxaldehyde

Cas:22065-85-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

N-Benzylpiperidine-4-carboxaldehyde Basic information Product Name: N-Benzylpiperidine-4-carboxaldehyde Synonyms: N-BENZYLPIPERIDINE-4-CARBOXALDEHYDE;1-BENZYL-PIPERIDINE-4-CARBALDEHYDE;1

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 22065-85-6 with best quality

Cas:22065-85-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-Piperidinecarboxaldehyde,1-(phenylmethyl)- 22065-85-6

Cas:22065-85-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: N-Benzylpiperidine-4-carboxaldehyde CAS: 22065-85-6 MF: C13H17NO MW: 203.28 EINECS: 244-757-7 Mol File: 22065-85-6.mol N-Benzylpiperidine-4-carboxaldehyde Structure N-Benzylpiperidine-4-carboxaldehyde Chemical Proper

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Piperidinecarboxaldehyde,1-(phenylmethyl)-

Cas:22065-85-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

4-Piperidinecarboxaldehyde,1-(phenylmethyl)-/ LIDE PHARMA- Factory supply / Best price

Cas:22065-85-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:22065-85-6

Cas:22065-85-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Specification:USP/EP Month production ablity:50kg/Month Low price& High quality Manufacturer Appearance:white powder Storage:Room Temperature Application:22065-85-6

1-Benzyl-4-Piperidine carboxaldehyde

Cas:22065-85-6

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

N-Benzy-4-Piperidine Carboxaldehyde

Cas:22065-85-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-Benzyl-4-piperidinecarboxaldehyde

Cas:22065-85-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

High quality 22065-85-6 low price N-Benzylpiperidine-4-carboxaldehyde in China Molecular Formula C13H17NO Molar Mass 203.28 Density 1.026 g/mL at 25 °C Melting Point 145-149 °C Boling

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colourless or light yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceu

4-Piperidinecarboxaldehyde,1-(phenylmethyl)-

Cas:22065-85-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top Purity N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

N-Benzy-4-Piperidine Carboxaldehyde

Cas:22065-85-6

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

C13H17NO N-Benzylpiperidine-4-carboxaldehyde 22065-85-6

Cas:22065-85-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

N-Benzy-4-Piperidine Carboxaldehyde

Cas:22065-85-6

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

4-Piperidinecarboxaldehyde,1-(phenylmethyl)-

Cas:22065-85-6

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

1-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

N-Benzylpiperidine-4-carboxaldehyde

Cas:22065-85-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Synthetic route

1-benzylpiperidine-4-carbonitrile
62718-31-4

1-benzylpiperidine-4-carbonitrile

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Stage #1: 1-benzylpiperidine-4-carbonitrile With diisobutylaluminium hydride In toluene at 0℃; for 1h;
Stage #2: With water; sodium hydroxide In methanol; toluene for 0.5h; pH=8; Temperature;
97.5%
1-benzyl-4-piperidinecarboxylic acid methyl ester
10315-06-7

1-benzyl-4-piperidinecarboxylic acid methyl ester

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
With red-aluminum/morpholine complex In toluene at -5 - 0℃; for 0.5h; Reagent/catalyst; Solvent; Inert atmosphere; Large scale;96.5%
Multi-step reaction with 2 steps
1: 69.5 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 50 °C
2: 94.3 percent / oxalyl chloride; dimethyl sulfoxide; Et3N / CH2Cl2 / 0.25 h / -55 °C
View Scheme
Multi-step reaction with 4 steps
1.1: water; methanol; sodium hydroxide / 2 h / Reflux
2.1: thionyl chloride / 2 h / Reflux
2.2: 0.5 h / Cooling with ice
3.1: thionyl chloride / 5 h / Reflux
4.1: diisobutylaluminium hydride / toluene / 1 h / 0 °C
4.2: 0.5 h / pH 8
View Scheme
1-benzyl-4-piperidinemethanol
67686-01-5

1-benzyl-4-piperidinemethanol

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
With oxalyl dichloride; dimethyl sulfoxide; triethylamine In dichloromethane at -70 - 20℃; Swern Oxidation;96%
With oxalyl dichloride; dimethyl sulfoxide; triethylamine In dichloromethane at -55℃; for 0.25h; Swern oxidation;94.3%
Stage #1: 1-benzyl-4-piperidinemethanol With dimethylsulfide; triethylamine In toluene at -15 - -10℃; Inert atmosphere;
Stage #2: With N-chloro-succinimide In toluene
85%
N-benzyl isonipecotic acid ethyl ester
24228-40-8

N-benzyl isonipecotic acid ethyl ester

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
With diisobutylaluminium hydride In hexane; toluene at -78℃; for 2.5h; Flow reactor;96%
With Red-ALP-KTB In various solvent(s) at 10℃;95%
Stage #1: N-benzyl isonipecotic acid ethyl ester With morpholine; diisobutylaluminium hydride In tetrahydrofuran; hexane at 0℃; for 3.16667h; Inert atmosphere;
Stage #2: With lithium diisobutylmethoxy aluminum hydride In tetrahydrofuran; hexane at 0℃; for 0.166667h; Inert atmosphere;
94%
pyrrolidine
123-75-1

pyrrolidine

N-benzyl isonipecotic acid ethyl ester
24228-40-8

N-benzyl isonipecotic acid ethyl ester

A

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

B

1-benzyl-4-piperidinemethanol
67686-01-5

1-benzyl-4-piperidinemethanol

C

N-benzyl-4-(pyrrolidin-1-ylmethyl)piperidine

N-benzyl-4-(pyrrolidin-1-ylmethyl)piperidine

D

N-benzyl-4-(pyrrolidin-1-ylcarbonyl)piperidine

N-benzyl-4-(pyrrolidin-1-ylcarbonyl)piperidine

Conditions
ConditionsYield
With Red-ALP In various solvent(s) at 20℃; for 2h;A 95%
B n/a
C n/a
D n/a
1-benzyl-1,2,3,6-tetrahydropyridine-4-carbaldehyde
503544-95-4

1-benzyl-1,2,3,6-tetrahydropyridine-4-carbaldehyde

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 20℃; for 3h;90%
1-benzyl-N,N-dimethylpiperidine-4-carboxamide

1-benzyl-N,N-dimethylpiperidine-4-carboxamide

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
With sodium hydride; sodium iodide In tetrahydrofuran at 60℃; chemoselective reaction;75%
1-benzyl-4-vinyl-piperidine
42790-44-3

1-benzyl-4-vinyl-piperidine

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
With PYRIMIDINE; sodium periodate; osmium(VIII) oxide In 1,4-dioxane; 2-methyl-propan-1-ol; water at 20℃; for 7h;74%
C14H16NO3(1-)*Na(1+)

C14H16NO3(1-)*Na(1+)

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Stage #1: C14H16NO3(1-)*Na(1+) With hydrogenchloride; water at 90℃; for 1.5 - 2h; Heating / reflux;
Stage #2: With ammonia In water at 15℃; pH=8.5 - 9.0; Product distribution / selectivity;
68%
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Stage #1: diazomethyl-trimethyl-silane With n-butyllithium; diisopropylamine In tetrahydrofuran at -78℃; for 1.25h;
Stage #2: 1-phenylmethyl-4-piperidone In tetrahydrofuran at -78 - 20℃; for 4h; Heating / reflux;
55%
With N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide
1-benzyl-4-methoxymethyl-piperidine
101775-64-8

1-benzyl-4-methoxymethyl-piperidine

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Stage #1: 1-benzyl-4-methoxymethyl-piperidine With hydrogenchloride; methanol; water for 3h; Heating / reflux;
Stage #2: With sodium hydroxide In water pH=12;
54%
1-Benzyl-4-(methoxymethylidene)-piperidine
120014-33-7

1-Benzyl-4-(methoxymethylidene)-piperidine

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Stage #1: 1-Benzyl-4-(methoxymethylidene)-piperidine With hydrogenchloride In methanol; water for 3h; Heating / reflux;
Stage #2: With sodium hydroxide In water pH=12;
54%
With hydrogenchloride; potassium carbonate In tetrahydrofuran
With formic acid In water at 35℃; for 3h; Inert atmosphere; Large scale;57.7 kg
N-benzyl-1-oxa-6-azaspiro[2,5]-octane
19867-34-6

N-benzyl-1-oxa-6-azaspiro[2,5]-octane

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
With magnesium bromide ethyl etherate In benzene at 40℃; for 0.333333h;17.5 g
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrabutylammonium bromide; NaOH / toluene; H2O / 4 h / 80 °C
2: 17.5 g / magnesium bromide etherate / benzene / 0.33 h / 40 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sodium t-butanolate / tetrahydrofuran / 1.5 h / 0 - 5 °C / Inert atmosphere; Large scale
1.2: 1 h / 5 °C / Large scale
2.1: formic acid / water / 3 h / 35 °C / Inert atmosphere; Large scale
View Scheme
N-benzyl-2-(4-methylphenylsulfonyl)acetamide
330173-08-5

N-benzyl-2-(4-methylphenylsulfonyl)acetamide

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: NaH / tetrahydrofuran / 0.25 h / 20 °C
1.2: 95 percent / tetrahydrofuran / 5 h / Heating
2.1: 90 percent / AlCl3; LiAlH4 / tetrahydrofuran / 3 h / 20 °C
3.1: 90 percent / HCl / acetone; H2O / 24 h / Heating
4.1: 90 percent / H2 / Pd/C / methanol / 3 h / 20 °C
View Scheme
1-benzyl-3-(4-methylphenylsulfonyl)-4-dimethoxymethylpiperidine-2,6-dione

1-benzyl-3-(4-methylphenylsulfonyl)-4-dimethoxymethylpiperidine-2,6-dione

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / AlCl3; LiAlH4 / tetrahydrofuran / 3 h / 20 °C
2: 90 percent / HCl / acetone; H2O / 24 h / Heating
3: 90 percent / H2 / Pd/C / methanol / 3 h / 20 °C
View Scheme
1-benzyl-4-(dimethoxymethyl)-3-(p-tolylsulfonyl)piperidine

1-benzyl-4-(dimethoxymethyl)-3-(p-tolylsulfonyl)piperidine

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / HCl / acetone; H2O / 24 h / Heating
2: 90 percent / H2 / Pd/C / methanol / 3 h / 20 °C
View Scheme
4-carbethoxypiperidine
1126-09-6

4-carbethoxypiperidine

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 93 percent / NaHCO3 / ethanol; H2O / 2 h / 80 °C
2: 95 percent / Red-ALP-KTB / various solvent(s) / 10 °C
View Scheme
Multi-step reaction with 3 steps
1: 76 percent / K2CO3 / ethanol / 72 h / Ambient temperature
2: 61 percent / LiAlH4 / tetrahydrofuran / 18 h / Heating
3: 1.) DMSO, (COCl)2, 2.) Et3N / 1.) CH2Cl2, from -65 deg C to -60 deg C, 15 min, 2.) CH2Cl2, from -78 deg C to RT, 6 h
View Scheme
Multi-step reaction with 3 steps
1.1: triethylamine / toluene / 10 - 75 °C / Large scale
2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 15 - 30 °C / Large scale
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -65 - -45 °C / Large scale
3.2: 0.5 h / -50 - -45 °C / Large scale
View Scheme
benzyl chloride
100-44-7

benzyl chloride

Fmoc-(S)-leucine bound to Wang resin

Fmoc-(S)-leucine bound to Wang resin

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 93 percent / NaHCO3 / ethanol; H2O / 2 h / 80 °C
2: 95 percent / Red-ALP-KTB / various solvent(s) / 10 °C
View Scheme
isonipecotic acid
498-94-2

isonipecotic acid

paraformaldehyde

paraformaldehyde

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 84 percent / SOCl2 / 20 h / 20 °C
2: 79.7 percent / Et3N / CH2Cl2 / 20 °C
3: 69.5 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 50 °C
4: 94.3 percent / oxalyl chloride; dimethyl sulfoxide; Et3N / CH2Cl2 / 0.25 h / -55 °C
View Scheme
methyl piperidine-4-carboxylate hydrochloride
7462-86-4

methyl piperidine-4-carboxylate hydrochloride

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 79.7 percent / Et3N / CH2Cl2 / 20 °C
2: 69.5 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 50 °C
3: 94.3 percent / oxalyl chloride; dimethyl sulfoxide; Et3N / CH2Cl2 / 0.25 h / -55 °C
View Scheme
Multi-step reaction with 5 steps
1.1: triethylamine / methanol / 6 h / Reflux
2.1: water; methanol; sodium hydroxide / 2 h / Reflux
3.1: thionyl chloride / 2 h / Reflux
3.2: 0.5 h / Cooling with ice
4.1: thionyl chloride / 5 h / Reflux
5.1: diisobutylaluminium hydride / toluene / 1 h / 0 °C
5.2: 0.5 h / pH 8
View Scheme
benzyl bromide
100-39-0

benzyl bromide

t-BuOCOCH2-X

t-BuOCOCH2-X

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 79.7 percent / Et3N / CH2Cl2 / 20 °C
2: 69.5 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 50 °C
3: 94.3 percent / oxalyl chloride; dimethyl sulfoxide; Et3N / CH2Cl2 / 0.25 h / -55 °C
View Scheme
benzyl chloride
100-44-7

benzyl chloride

metal

metal

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 76 percent / K2CO3 / ethanol / 72 h / Ambient temperature
2: 61 percent / LiAlH4 / tetrahydrofuran / 18 h / Heating
3: 1.) DMSO, (COCl)2, 2.) Et3N / 1.) CH2Cl2, from -65 deg C to -60 deg C, 15 min, 2.) CH2Cl2, from -78 deg C to RT, 6 h
View Scheme
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

(methoxymethyl)triphenylphosphonium chloride
4009-98-7

(methoxymethyl)triphenylphosphonium chloride

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Stage #1: (methoxymethyl)triphenylphosphonium chloride With n-butyllithium In diethyl ether; hexane at 0 - 20℃; for 0.5h;
Stage #2: 1-phenylmethyl-4-piperidone In diethyl ether; hexane at 20℃; for 3h;
Stage #3: With hydrogenchloride; sodium hydroxide more than 3 stages;
benzyl chloride
100-44-7

benzyl chloride

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / toluene / 10 - 75 °C / Large scale
2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 15 - 30 °C / Large scale
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -65 - -45 °C / Large scale
3.2: 0.5 h / -50 - -45 °C / Large scale
View Scheme
Multi-step reaction with 3 steps
1.1: toluene / 2 h / 10 - 15 °C
1.2: 6 h / 70 °C
2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 0.25 h / 15 - 30 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -55 - -48 °C
3.2: 1.08 h / -55 - -20 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / ethanol / 3 h / Reflux; Large scale
2: red-aluminum/morpholine complex / toluene / 0.5 h / -5 - 0 °C / Inert atmosphere; Large scale
View Scheme
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / ethanol / 3 h / Reflux
2: red-aluminum/morpholine complex / cyclohexane / 3 h / 0 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1.1: potassium carbonate / toluene / 0.25 h
1.2: 4 h / 100 °C
2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 2 h / 20 °C / Inert atmosphere
3.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / -70 - 20 °C
View Scheme
4-piperidinecarboxylic acid methyl ester hydrochloride

4-piperidinecarboxylic acid methyl ester hydrochloride

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / ethanol / 3 h / Reflux; Large scale
2: red-aluminum/morpholine complex / toluene / 0.5 h / -5 - 0 °C / Inert atmosphere; Large scale
View Scheme
benzaldehyde
100-52-7

benzaldehyde

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen; platinum on activated charcoal / toluene / 80 °C / Flow reactor
2: diisobutylaluminium hydride / toluene; hexane / 2.5 h / -78 °C / Flow reactor
View Scheme
1-benzyl-piperidine-4-carboxylic acid amide
62992-68-1

1-benzyl-piperidine-4-carboxylic acid amide

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: thionyl chloride / 5 h / Reflux
2.1: diisobutylaluminium hydride / toluene / 1 h / 0 °C
2.2: 0.5 h / pH 8
View Scheme
isonipecotic acid
498-94-2

isonipecotic acid

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: thionyl chloride / 2 h / Reflux
2.1: triethylamine / methanol / 6 h / Reflux
3.1: water; methanol; sodium hydroxide / 2 h / Reflux
4.1: thionyl chloride / 2 h / Reflux
4.2: 0.5 h / Cooling with ice
5.1: thionyl chloride / 5 h / Reflux
6.1: diisobutylaluminium hydride / toluene / 1 h / 0 °C
6.2: 0.5 h / pH 8
View Scheme
5,6-dimethoxy-1-indanone
2107-69-9

5,6-dimethoxy-1-indanone

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

1-benzyl-4-<(5,6-dimethoxy-1-oxoindan-2-ylidenyl)methyl>piperidine
120014-07-5

1-benzyl-4-<(5,6-dimethoxy-1-oxoindan-2-ylidenyl)methyl>piperidine

Conditions
ConditionsYield
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In water; toluene at 20℃; Product distribution / selectivity; Inert atmosphere; Reflux;100%
With sodium methylate In methanol; ethanol at 79℃; for 1.58333h; Product distribution / selectivity; Heating / reflux;93.4%
With sodium methylate In methanol at 66℃; for 1h; Product distribution / selectivity; Heating / reflux;93.9%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

tris-iso-propylsilyl acetylene
89343-06-6

tris-iso-propylsilyl acetylene

(R)-(-)-1-(N-benzyl-4-piperidinyl)-3-triisopropylsilyl-2-propyn-1-ol

(R)-(-)-1-(N-benzyl-4-piperidinyl)-3-triisopropylsilyl-2-propyn-1-ol

Conditions
ConditionsYield
With (αR,2S)-(-)-1-(2-diphenylphosphinobenzyl)-α-(2,2-dimethylpropynyl)-2-pyrrolidinemethanol; copper (I) tert-butoxide In tert-butyl alcohol at 25℃; for 72h; Inert atmosphere; enantioselective reaction;99%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

nitromethane
75-52-5

nitromethane

C14H20N2O3

C14H20N2O3

Conditions
ConditionsYield
With potassium fluoride In isopropyl alcohol at 20℃;96%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

3-methoxyphenyl bromide
2398-37-0

3-methoxyphenyl bromide

N-benzyl-4-[hydroxy(3-methoxyphenyl)methyl]piperidine
255723-94-5

N-benzyl-4-[hydroxy(3-methoxyphenyl)methyl]piperidine

Conditions
ConditionsYield
Stage #1: 3-methoxyphenyl bromide With magnesium In tetrahydrofuran for 0.5h; Grignard reaction; Heating;
Stage #2: N-benzyl-4-formylpiperidine In tetrahydrofuran at 20℃; for 2h; Addition;
94.3%
5,6-dimethoxy-1-indanone
2107-69-9

5,6-dimethoxy-1-indanone

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

(E)-2-((1-benzylpiperidine-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

(E)-2-((1-benzylpiperidine-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With potassium tert-butylate In tert-butyl alcohol at 0 - 25℃; for 1.25h; Product distribution / selectivity;92.2%
With sodium methylate In isopropyl alcohol at 0 - 25℃; for 3.25h; Product distribution / selectivity;92.5%
With tetrabutylammomium bromide; potassium hydroxide In dichloromethane; water at 38℃; for 1.5h;90%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

diethyl cyanophosphonate
2942-58-7

diethyl cyanophosphonate

lithium cyanide
2408-36-8

lithium cyanide

(1-benzylpiperidin-4-yl)cyanomethyl diethylphosphate

(1-benzylpiperidin-4-yl)cyanomethyl diethylphosphate

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 0.5h;92%
5,6-dimethoxy-1-indanone
2107-69-9

5,6-dimethoxy-1-indanone

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

1-benzyl-4-<(5,6-dimethoxy-1-oxoindan-2-ylidenyl)methyl>piperidine hydrochloride

1-benzyl-4-<(5,6-dimethoxy-1-oxoindan-2-ylidenyl)methyl>piperidine hydrochloride

Conditions
ConditionsYield
Stage #1: 5,6-dimethoxy-1-indanone; N-benzyl-4-formylpiperidine In dichloromethane at 25 - 30℃;
Stage #2: With potassium hydroxide In methanol; dichloromethane at 0 - 30℃;
91.3%
2-methylbenzothiazol-5-yl methyl ketone
20077-92-3

2-methylbenzothiazol-5-yl methyl ketone

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

3-(1-benzylpiperidin-4-yl)-3-hydroxy-1-(2-methylbenzothiazol-6-yl)propan-1-one

3-(1-benzylpiperidin-4-yl)-3-hydroxy-1-(2-methylbenzothiazol-6-yl)propan-1-one

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.75h;90%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

(4-chlorphenyl)magnesium bromide
873-77-8

(4-chlorphenyl)magnesium bromide

(1-benzylpiperidin-4-yl)(4-chlorophenyl)methanol
1226878-35-8

(1-benzylpiperidin-4-yl)(4-chlorophenyl)methanol

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 0.55h; Grignard reaction; Inert atmosphere;90%
Diethyl (2-oxopropyl)phosphonate
1067-71-6

Diethyl (2-oxopropyl)phosphonate

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

(E)-4-(1-benzylpiperidin-4-yl)but-3-en-2-one
1335032-58-0

(E)-4-(1-benzylpiperidin-4-yl)but-3-en-2-one

Conditions
ConditionsYield
Stage #1: Diethyl (2-oxopropyl)phosphonate With potassium carbonate In tetrahydrofuran at 20℃; for 0.583333h; Reflux;
Stage #2: N-benzyl-4-formylpiperidine In tetrahydrofuran for 3h; Wittig reaction; Reflux;
90%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

5,6-Diethoxy-1-indanone
137013-02-6

5,6-Diethoxy-1-indanone

1-benzyl-4-[(5,6-diethoxy-1-indanon)-2-ylidene]methylpiperidine

1-benzyl-4-[(5,6-diethoxy-1-indanon)-2-ylidene]methylpiperidine

Conditions
ConditionsYield
With sodium methylate In tetrahydrofuran; methanol; water for 2h;89%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

3-chloro-1-(3,4-dimethoxyphenyl)propan-1-one
4693-38-3

3-chloro-1-(3,4-dimethoxyphenyl)propan-1-one

1-benzyl-4-<(5,6-dimethoxy-1-oxoindan-2-ylidenyl)methyl>piperidine
120014-07-5

1-benzyl-4-<(5,6-dimethoxy-1-oxoindan-2-ylidenyl)methyl>piperidine

Conditions
ConditionsYield
With triethylammonium tetrachloroaluminate at 55 - 175℃; for 11h; Temperature; Reagent/catalyst; Concentration; Inert atmosphere;89%
5,6-dimethoxy-1-indanone
2107-69-9

5,6-dimethoxy-1-indanone

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

donepezil
120014-06-4

donepezil

Conditions
ConditionsYield
With aluminum oxide; Pt/Al2O3 In tetrahydrofuran; ethanol; water; isopropyl alcohol at 45 - 55℃; for 7h; Temperature; Solvent; Reagent/catalyst; Aldol Condensation;88%
Multi-step reaction with 2 steps
1: sodium methylate / tetrahydrofuran
2: palladium 10% on activated carbon; hydrogenchloride / ethanol; water
View Scheme
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

(4-iodo-5-methoxypyrrolo[2,3-b]pyridin-1-yl)triisopropylsilane

(4-iodo-5-methoxypyrrolo[2,3-b]pyridin-1-yl)triisopropylsilane

(1-benzyl-4-piperidyl)-(5-methoxy-1-triisopropylsilylpyrrolo[2,3-b]pyridin-4-yl)methanol

(1-benzyl-4-piperidyl)-(5-methoxy-1-triisopropylsilylpyrrolo[2,3-b]pyridin-4-yl)methanol

Conditions
ConditionsYield
Stage #1: (4-iodo-5-methoxypyrrolo[2,3-b]pyridin-1-yl)triisopropylsilane With isopropylmagnesium chloride In tetrahydrofuran at 0℃; for 0.666667h;
Stage #2: N-benzyl-4-formylpiperidine In tetrahydrofuran at 0℃; for 1h;
84.8%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

diethyl ((6-((2-methyl-1-oxo-1-(phenylamino)propan-2-yl)oxy)quinolin-2-yl)methyl)phosphonate

diethyl ((6-((2-methyl-1-oxo-1-(phenylamino)propan-2-yl)oxy)quinolin-2-yl)methyl)phosphonate

(E)-2-((3-(2-(1-benzylpiperidin-4-yl)vinyl)isoquinolin-7-yl)oxy)-2-methyl-N-phenylpropanamide

(E)-2-((3-(2-(1-benzylpiperidin-4-yl)vinyl)isoquinolin-7-yl)oxy)-2-methyl-N-phenylpropanamide

Conditions
ConditionsYield
Stage #1: diethyl ((6-((2-methyl-1-oxo-1-(phenylamino)propan-2-yl)oxy)quinolin-2-yl)methyl)phosphonate With n-butyllithium In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: N-benzyl-4-formylpiperidine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
84%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

diethyl cyanomethyl phosphonate
50586-62-4

diethyl cyanomethyl phosphonate

(2E)-3-(1-benzylpiperidin-4-yl)prop-2-enenitrile
151097-69-7

(2E)-3-(1-benzylpiperidin-4-yl)prop-2-enenitrile

Conditions
ConditionsYield
Stage #1: diethyl cyanomethyl phosphonate With potassium carbonate In tetrahydrofuran at 20℃; for 0.5h; Reflux;
Stage #2: N-benzyl-4-formylpiperidine In tetrahydrofuran for 12h; Reflux;
83%
5,6-dimethoxy-1-indanone
2107-69-9

5,6-dimethoxy-1-indanone

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

2-((1-benzyl-piperidin-4-yl)-hydroxymethyl)-5,6-dimethoxyindan-1-one
197010-20-1

2-((1-benzyl-piperidin-4-yl)-hydroxymethyl)-5,6-dimethoxyindan-1-one

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In water; toluene for 4h; Reflux; Large scale;81.29%
picolinic acid hydrazide
1452-63-7

picolinic acid hydrazide

1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

(E)-N'-((1-benzylpiperidin-4-yl)methylene)picolinohydrazide

(E)-N'-((1-benzylpiperidin-4-yl)methylene)picolinohydrazide

Conditions
ConditionsYield
In methanol at 100℃; for 0.5h; Microwave irradiation;80%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

2,2,2-trifluorodiazoethane
371-67-5

2,2,2-trifluorodiazoethane

N-butylamine
109-73-9

N-butylamine

1-benzyl-4-(1-butyl-4-(trifluoromethyl)-4,5-dihydro-1H-1,2,3-triazol-5-yl)piperidine

1-benzyl-4-(1-butyl-4-(trifluoromethyl)-4,5-dihydro-1H-1,2,3-triazol-5-yl)piperidine

Conditions
ConditionsYield
With silver carbonate In toluene at 25℃; for 8h; diastereoselective reaction;79%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

(3-fluorobenzyl)(triphenyl)phosphonium bromide
89302-81-8

(3-fluorobenzyl)(triphenyl)phosphonium bromide

(E)-1-benzyl-4-(3-fluorostyryl)piperidine

(E)-1-benzyl-4-(3-fluorostyryl)piperidine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; Cooling with ice;78.1%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

2-bromo-5,6-dimethoxy-1-indanone
2747-08-2

2-bromo-5,6-dimethoxy-1-indanone

(E)-2-((1-benzylpiperidine-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

(E)-2-((1-benzylpiperidine-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With 1-phenylphospholane-1-oxide; diphenylsilane; N-ethyl-N,N-diisopropylamine In toluene at 100℃; for 24h; Wittig Olefination; Inert atmosphere;76%
1-benzyl-4-formylpiperidine
22065-85-6

1-benzyl-4-formylpiperidine

diethyl (1-tritylimidazol-4-yl)methylphosphonate
473659-21-1

diethyl (1-tritylimidazol-4-yl)methylphosphonate

(E)-1-benzyl-4-(1-triphenylmethylimidazol-4-ylethylene)piperidine

(E)-1-benzyl-4-(1-triphenylmethylimidazol-4-ylethylene)piperidine

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran for 2h; Horner-Wadsworth-Emmons reaction; Heating;74%
With potassium tert-butylate In tetrahydrofuran for 2h; Heating / reflux;74%
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View