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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Ethyl (R)-3-Hydroxybutyrate supplier in China

Cas:24915-95-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Sinoway Industrial Co., Ltd.

Assay: 98% up by GC; Stable supply with over 50Mt annually; Appearance:Colorless to light yellow liquid Storage:room temprature Package:25kg/drum Application:Intermediate in organic synthesis Port:Beijing/Shanghai/Shenzhen/Hangzhou

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Kilogram

FOB Price: $100.0

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit

Ethyl (R)-(-)-3-Hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply ethyl (3R)-3-hydroxybutanoate

Cas:24915-95-5

Min.Order:1

Negotiable

Type:Other

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product specifica

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(R)-(-)-3-Hydroxybutyric acid ethyl ester

Cas:24915-95-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Ethyl (R) -3-Hydroxybutyrate; CAS No. 24915-95-5

Cas:24915-95-5

Min.Order:1 Kilogram

FOB Price: $60.0 / 100.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Ethyl (R)-3-hydroxybutyrate Basic information Product Name: Ethyl (R)-3-hydroxybutyrate Synonyms: (R)-(-)-ETHYL 3-HYDROXYBUTANOATE;(R)-(-)-ETHYL 3-HYDROXYBUTYRATE;(R)-(-)-3-HYDROXYBUTYRI

(R)-(-)-ETHYL 3-HYDROXYBUTANOATE

Cas:24915-95-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 24915-95-5 with best quality

Cas:24915-95-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:clear colorless liquid Storage:2-8°C Package:25kg/Barrel Application:Pharmaceutical intermediates Transportation:Express/Sea/Air Port:Any port in China

High qualityEthyl (R)-3-hydroxybutyrate Factory supply

Cas:24915-95-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Butanoic acid,3-hydroxy-, ethyl ester, (3R)- 24915-95-5

Cas:24915-95-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Ethyl (R)-3-hydroxybutyrate CAS:24915-95-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

Ethyl (R)-3-hydroxybutyrate CAS:24915-95-5

Cas:24915-95-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Butanoic acid,3-hydroxy-, ethyl ester, (3R)-

Cas:24915-95-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:24915-95-5

Cas:24915-95-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFUCHEM--24915-95-5--High purity 6-Methylpyridine-3-carboxylic acid factory price

Cas:24915-95-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl (R)-(-)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

lower price and high quality Appearance:White Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical Intermediate Transportation:shipping,land,a

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Ethyl (R)-3-Hydroxybutyrate

Cas:24915-95-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

24915-95-5 on hot sale24915-95-5 Ethyl (R)-3-hydroxybutyrateEthyl (R)-3-hydroxybutyrate manufacturer

Cas:24915-95-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Ethyl(R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Ethyl (R)-3-hydroxybutyrate Basic information Product Name: Ethyl (R)-3-hydroxybutyrate Synonyms: (R)-(-)-ETHYL 3-HYDROXYBUTANOATE;(R)-(-)-ETHYL 3-HYDROXYBUTYRATE;(R)-(-)-3-HYDROXYBUTYRIC ACID ETHYL ESTER;(R)-3-HYDROXYBUTYRIC ACID ETHYL ESTER;

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFUCHEM--24915-95-5--High purity 6-Methylpyridine-3-carboxylic acid factory price

Cas:24915-95-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

TIANFUCHEM--24915-95-5--High purity 6-Methylpyridine-3-carboxylic acid factory price

Cas:24915-95-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

TIANFUCHEM--24915-95-5--High purity 6-Methylpyridine-3-carboxylic acid factory price

Cas:24915-95-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Product name Ethyl (R)-3-hydroxybutyrate Content ≥98% CAS NO. 24915-95-5 Package Structure Formula Appearance:Detai

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Butanoic acid,3-hydroxy-, ethyl ester, (3R)-

Cas:24915-95-5

Min.Order:0

Negotiable

Type:Other

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Ethyl (R)-3-hydroxybutyrate

Cas:24915-95-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

TIANFUCHEM--24915-95-5--High purity 6-Methylpyridine-3-carboxylic acid factory price

Cas:24915-95-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Synthetic route

ethyl acetoacetate
141-97-9

ethyl acetoacetate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With (S)-4,12-bis(diphenylphosphino)-<2.2>paracyclophane-Ru(II)bis(trifluoroacetate); hydrogen; tetra-(n-butyl)ammonium iodide In methanol; water at -5℃; under 2585.7 Torr; for 18h;100%
With hydrogen; Ru(R-Xyl-P-Phos)(C6H6)Cl2 In ethanol; dichloromethane at 70℃; under 10343 Torr; for 1h;100%
With [(+)-N,N'-Me2-3,3'-(Ph2P)2-1,1'-biindole]RuCl2; hydrogen In methanol; water at 45℃; under 79805.4 Torr; for 0.5h;100%
ethyl 3-hydroxybutyrate
5405-41-4

ethyl 3-hydroxybutyrate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With alcohol dehydrogenase from Thermoanaerobium brockii; NADH-specific (R)-selective-ADH; YcnD-oxidoreductase at 30℃; for 24h; pH=7.5; aq. buffer; Resolution of racemate; Enzymatic reaction; optical yield given as %ee; enantiospecific reaction;99%
(R)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate
1006696-12-3

(R)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butanoate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sodium perborate In tetrahydrofuran; water at 20℃;94%
With sodium peroxoborate tetrahydrate In tetrahydrofuran; water at 20℃; for 3h;84%
With sodium perborate tetrahydrate In tetrahydrofuran; water Inert atmosphere;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

Conditions
ConditionsYield
With citrate-phosphate-borate buffer for 24h; Ambient temperature; baker's yeast immobilized in calcium alginate; Title compound not separated from byproducts;A n/a
B 85%
With Convolvulus sepium for 120h; pH=5.8; aq. phosphate buffer; optical yield given as %ee;A n/a
B 70%
yeast Conversion of starting material; Enzymatic reaction;A n/a
B 26%
ethanol
64-17-5

ethanol

PHB/PHV biopolymer

PHB/PHV biopolymer

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid In 1,2-dichloro-ethane for 48h; Heating;A 84%
B 59%
poly-(3(R)-hydroxy butyric acid

poly-(3(R)-hydroxy butyric acid

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid In ethanol Heating;83%
ethanol
64-17-5

ethanol

poly((R)-hydroxybutanoate)

poly((R)-hydroxybutanoate)

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid In 1,2-dichloro-ethane Heating;82%
ethanol
64-17-5

ethanol

poly-(R)-3-hydroxybutyrate

poly-(R)-3-hydroxybutyrate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid In 1,2-dichloro-ethane for 75h; Reflux;81%
poly-β-hydroxybutyrate (PHB)

poly-β-hydroxybutyrate (PHB)

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid In ethanol; 1,2-dichloro-ethane for 37h; Heating; Irradiation;80%
ethanol
64-17-5

ethanol

poly-3(R)-hydroxybutyrate

poly-3(R)-hydroxybutyrate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid In 1,2-dichloro-ethane for 96h; Heating;71%
ethanol
64-17-5

ethanol

(R)-4-methyloxetan-2-one
32082-74-9

(R)-4-methyloxetan-2-one

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid at 20℃;66%
With sulfuric acid
ethyl 4,4,4-trifluoroacetoacetate
372-31-6

ethyl 4,4,4-trifluoroacetoacetate

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

ethyl (3S)-4,4,4-trifluoro-3-hydroxybutanoate
372-30-5, 85571-85-3, 88968-78-9, 99437-70-4

ethyl (3S)-4,4,4-trifluoro-3-hydroxybutanoate

C

ethyl (3R)-4,4,4-trifluoro-3-hydroxybutanoate
85571-85-3

ethyl (3R)-4,4,4-trifluoro-3-hydroxybutanoate

Conditions
ConditionsYield
With Fala baker' yeast; allyl alcohol Microbiological reaction;A 62%
B n/a
C n/a
ethanol
64-17-5

ethanol

poly-[(R)-3-hydroxybutyric] acid

poly-[(R)-3-hydroxybutyric] acid

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid In 1,2-dichloro-ethane for 48h;60%
ethyl (R)-3-(((2,2,2-trichloroethoxy)carbonyl)oxy)butanoate

ethyl (R)-3-(((2,2,2-trichloroethoxy)carbonyl)oxy)butanoate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With trimethyltin(IV) hydroxide In 1,2-dichloro-ethane at 60℃; for 10h; Inert atmosphere; chemoselective reaction;58%
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

3,3-bismethoxybutyric acid methyl ester
29267-46-7

3,3-bismethoxybutyric acid methyl ester

Conditions
ConditionsYield
With <(+)-2,2'-bis(diphenylphosphino)-4,4',6,6'-tetramethyl-3,3'-bibenzothiophene>RuCl2; hydrogen In methanol at 70℃; under 73550.8 Torr; for 2h; Yield given;A n/a
B 5%
ethanol
64-17-5

ethanol

(R)-3-hydroxybutyric acid
625-72-9

(R)-3-hydroxybutyric acid

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid
ethyl 3-hydroxybutyrate
5405-41-4

ethyl 3-hydroxybutyrate

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

Conditions
ConditionsYield
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With pentyl cage-coated capillary column Resolution of racemate;
With homochiral metal-organic cage [Zn3(deprotonated [3+3] macrocyclic Schiff base of trans-1,2-diaminocyclohexane and 4-tert-butyl-2,6-diformylphenol)2] coated capillary column In dichloromethane at 118℃; Resolution of racemate; enantioselective reaction;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

(S)-3-Hydroxybutanoic Acid
6168-83-8

(S)-3-Hydroxybutanoic Acid

B

(R)-3-hydroxybutyric acid
625-72-9

(R)-3-hydroxybutyric acid

C

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

D

ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

Conditions
ConditionsYield
With Halobacterium halobium; pepton; potassium chloride; water; sodium citrate; magnesium sulfate; sodium chloride at 40℃; for 120h; Irradiation; Yields of byproduct given. Title compound not separated from byproducts;
With Halobacterium halobium; pepton; potassium chloride; sodium citrate; magnesium sulfate; sodium chloride In water at 40℃; for 120h; Irradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
ethyl 3-nitro-oxy-butanoate
100009-46-9

ethyl 3-nitro-oxy-butanoate

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol Yield given. Yields of byproduct given. Title compound not separated from byproducts;
ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With toluene-4-sulfonic acid 2.) MeOH, 1 h, room temperature; Yield given;
2-((R)-1-Hydroxy-ethyl)-[1,3]dithiolane-2-carboxylic acid ethyl ester

2-((R)-1-Hydroxy-ethyl)-[1,3]dithiolane-2-carboxylic acid ethyl ester

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sodium tetrahydroborate; hydrogen; nickel dichloride for 16h; Ambient temperature; Yield given;
ethanol
64-17-5

ethanol

poly(R)-3-hydroxybutanoic acid (PHB)

poly(R)-3-hydroxybutanoic acid (PHB)

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid
ethanol
64-17-5

ethanol

poly-(R)-3-hydroxybuttersaeure

poly-(R)-3-hydroxybuttersaeure

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With sulfuric acid 1.) 1,2-dichloroethane, reflux, 2 h; 2.) reflux, 48 h; Yield given. Multistep reaction;
ethyl 4,4,4-trifluoroacetoacetate
372-31-6

ethyl 4,4,4-trifluoroacetoacetate

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

ethyl (3S)-4,4,4-trifluoro-3-hydroxybutanoate
372-30-5, 85571-85-3, 88968-78-9, 99437-70-4

ethyl (3S)-4,4,4-trifluoro-3-hydroxybutanoate

C

ethyl acetoacetate
141-97-9

ethyl acetoacetate

D

ethyl (3R)-4,4,4-trifluoro-3-hydroxybutanoate
85571-85-3

ethyl (3R)-4,4,4-trifluoro-3-hydroxybutanoate

Conditions
ConditionsYield
With Fala baker' yeast; allyl alcohol
poly-(R)-(-)-3-hydroxybutyrate

poly-(R)-(-)-3-hydroxybutyrate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With hydrogenchloride; ethanol In 1,2-dichloro-ethane for 12h; Heating;0.93 g
ethanol
64-17-5

ethanol

poly[(R)-hydroxybutyrate] BIOPOL D300G

poly[(R)-hydroxybutyrate] BIOPOL D300G

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
Stage #1: poly[(R)-hydroxybutyrate] BIOPOL D300G In dichloromethane at 83℃; for 2h;
Stage #2: ethanol With sulfuric acid In dichloromethane for 71h; Heating; Title compound not separated from byproducts;
trans-Crotonaldehyde
123-73-9

trans-Crotonaldehyde

ethanol
64-17-5

ethanol

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

Conditions
ConditionsYield
Stage #1: trans-Crotonaldehyde; ethanol With dihydrogen peroxide In chloroform at -20℃; for 16h;
Stage #2: With N-ethyl-N,N-diisopropylamine In chloroform at 30℃; for 15h; Further stages. Title compound not separated from byproducts.;
ethyl (S)-3-tosyloxy-butanoate
100009-40-3

ethyl (S)-3-tosyloxy-butanoate

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / (n-Bu4)N(1+)*NO3(1-) / benzene / 6 h / Heating
2: H2 / Pd/C / methanol
View Scheme
acetylacetone
123-54-6

acetylacetone

A

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

B

ethyl (S)-3-hydroxybutyrate
56816-01-4

ethyl (S)-3-hydroxybutyrate

Conditions
ConditionsYield
With D-glucose In phosphate buffer at 30℃; for 12h; pH=7; Title compound not separated from byproducts.;
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

ethyl (R)-3-[(tert-butyldimethylsilyl)oxy]butanoate
109715-46-0

ethyl (R)-3-[(tert-butyldimethylsilyl)oxy]butanoate

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 0℃;100%
With 1H-imidazole In dichloromethane100%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;100%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

ethyl vinyl ether
109-92-2

ethyl vinyl ether

(R)-3-(2-Ethoxy-ethoxy)-butyric acid ethyl ester

(R)-3-(2-Ethoxy-ethoxy)-butyric acid ethyl ester

Conditions
ConditionsYield
trifluoroacetic acid100%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

(3R,2'RS)-3-<(Tetrahydropyran-2'-yl)oxy>buttersaeure-ethylester
90410-58-5

(3R,2'RS)-3-<(Tetrahydropyran-2'-yl)oxy>buttersaeure-ethylester

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane at 0℃; for 0.25h;100%
With toluene-4-sulfonic acid In diethyl ether100%
With pyridinium p-toluenesulfonate In dichloromethane at 0 - 20℃; for 24h; Inert atmosphere; Schlenk technique;91%
With toluene-4-sulfonic acid
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

(R)-3-(tert-butyl-diphenyl-silanyloxy)-butyraldehyde
183310-90-9

(R)-3-(tert-butyl-diphenyl-silanyloxy)-butyraldehyde

Conditions
ConditionsYield
Stage #1: Ethyl (R)-3-hydroxybutanoate; tert-butylchlorodiphenylsilane With 1H-imidazole; dmap In dichloromethane
Stage #2: With diisobutylaluminium hydride In dichloromethane at -78℃; Further stages.;
100%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

ethyl vinyl ether
109-92-2

ethyl vinyl ether

ethyl-3-(1-ethoxyethoxy)-butanoate
79414-11-2, 79414-12-3, 82614-86-6

ethyl-3-(1-ethoxyethoxy)-butanoate

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In dichloromethane for 1h; Ambient temperature;99%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

ethyl (R)-3-(tert-butyldiphenylsilyloxy)butyrate
147963-63-1

ethyl (R)-3-(tert-butyldiphenylsilyloxy)butyrate

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide99%
With 1H-imidazole; dmap In dichloromethane at 0 - 20℃;99%
With 1H-imidazole In N,N-dimethyl-formamide for 72h; Ambient temperature;96%
With 1H-imidazole In N,N-dimethyl-formamide for 3h; Ambient temperature;95%
With 1H-imidazole In dichloromethane at 0 - 20℃; for 6h;80%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

(-)-(R)-Ethyl 3-(mesyloxy)butanoate
126434-58-0

(-)-(R)-Ethyl 3-(mesyloxy)butanoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere;99%
With triethylamine In dichloromethane at 0℃; for 1h;97%
With triethylamine In dichloromethane75%
methanol
67-56-1

methanol

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

Conditions
ConditionsYield
scandium tris(trifluoromethanesulfonate) at 64℃; for 10h;98%
(EtO)3TiO(CH2)2OTi(OEt)3 autoclave, 1.) 160 deg C, 17 bar, 2 h; 2.) 115 deg C, 3.5 bar, 27 h;82%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

triethylsilyl chloride
994-30-9

triethylsilyl chloride

ethyl (R)-3-((triethylsilyl)oxy)butanoate

ethyl (R)-3-((triethylsilyl)oxy)butanoate

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 18h;96%
With 1H-imidazole In dichloromethane
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

(-)-(R)-Ethyl 3-<(p-tolylsulfonyl)oxy>butanoate
121404-60-2

(-)-(R)-Ethyl 3-<(p-tolylsulfonyl)oxy>butanoate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 12h;95%
With pyridine In chloroform at 0℃; for 12h;71%
With pyridine at 0℃; for 24h;22.1 g
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

ethyl (R)-3-[(tert-butyldimethylsilyl)oxy]butanoate
109715-46-0

ethyl (R)-3-[(tert-butyldimethylsilyl)oxy]butanoate

Conditions
ConditionsYield
With 2,6-dimethylpyridine In dichloromethane at 0 - 20℃; for 2.5h;95%
With pyridine In dichloromethane at 0 - 20℃;62%
With pyridine Etherification;
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

chloromethyl methyl ether
107-30-2

chloromethyl methyl ether

(R)-ethyl 3-(methoxymethoxy)butanoate
272125-68-5

(R)-ethyl 3-(methoxymethoxy)butanoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;95%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Etherification;86%
With N-ethyl-N,N-diisopropylamine In dichloromethane75%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

methyl 3'-(cyanocarbonyl)-2,2'-binaphthalene-3-carboxylate
386707-15-9

methyl 3'-(cyanocarbonyl)-2,2'-binaphthalene-3-carboxylate

(R)-4-ethoxy-4-oxobutan-2-yl methyl 2,2'-binaphthalene-3,3'-dicarboxylate

(R)-4-ethoxy-4-oxobutan-2-yl methyl 2,2'-binaphthalene-3,3'-dicarboxylate

Conditions
ConditionsYield
With dmap In acetonitrile at 20℃; for 2h;95%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

methyl iodide
74-88-4

methyl iodide

Conditions
ConditionsYield
Stage #1: Ethyl (R)-3-hydroxybutanoate With n-butyllithium; diisopropylamine In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - -40℃; for 0.333333h; Frater-Seebach alkylation; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - 0℃; Frater-Seebach alkylation; Inert atmosphere; enantioselective reaction;
94%
Stage #1: Ethyl (R)-3-hydroxybutanoate With lithium diisopropyl amide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - -40℃; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -78 - 0℃; for 2h; Inert atmosphere;
92%
With lithium diisopropyl amide In tetrahydrofuran at -78℃;84%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

(R)-3-hydroxybutyric acid
625-72-9

(R)-3-hydroxybutyric acid

Conditions
ConditionsYield
With potassium hydroxide at 0℃; for 24h;93%
With sodium hydroxide In water at 10℃; for 6h;85%
With potassium hydroxide for 12h; Ambient temperature;
(η5-C5H4CH3)3Pr
78869-44-0

(η5-C5H4CH3)3Pr

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

2Pr(3+)*4C5H4CH3(1-)*2OCH(CH3)CH2COOC2H5(1-)=[(C5H4CH3)2Pr(OCH(CH3)CH2COOC2H5)]2

2Pr(3+)*4C5H4CH3(1-)*2OCH(CH3)CH2COOC2H5(1-)=[(C5H4CH3)2Pr(OCH(CH3)CH2COOC2H5)]2

Conditions
ConditionsYield
In toluene N2-atmosphere; equimolar amts., -70°C; elem. anal.;93%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

(2-trimethylethylsilylethoxy)methyl chloride
76513-69-4

(2-trimethylethylsilylethoxy)methyl chloride

Ethyl (3R)-3-{[2-(trimethylsilyl)ethoxy]methoxy}butanoate
1237525-17-5

Ethyl (3R)-3-{[2-(trimethylsilyl)ethoxy]methoxy}butanoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 18h;93%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In dichloromethane for 3h; Ambient temperature;92.5%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

(R)-3-hydroxy-butyric acid hydrazide

(R)-3-hydroxy-butyric acid hydrazide

Conditions
ConditionsYield
With hydrazine hydrate In ethanol at 90℃; for 16h; Inert atmosphere;92%
With hydrazine hydrate In ethanol at 90℃; for 16h;92%
With hydrazine hydrate In ethanol; water Reflux;1.95 g
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

potassium (R)-3-hydroxybutyrate
110972-51-5

potassium (R)-3-hydroxybutyrate

Conditions
ConditionsYield
With potassium hydroxide In water at 10℃; for 5h;88.2%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

benzylamine
100-46-9

benzylamine

(R)-N-benzyl-3-hydroxybutanamide
146679-25-6

(R)-N-benzyl-3-hydroxybutanamide

Conditions
ConditionsYield
Stage #1: benzylamine With trimethylaluminum In toluene at -5 - 20℃;
Stage #2: Ethyl (R)-3-hydroxybutanoate In toluene at -5 - 20℃; for 15.5h;
88%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

O-(4-methoxybenzyl)-trichloroacetimidate
89238-99-3

O-(4-methoxybenzyl)-trichloroacetimidate

(R)-3-(4-Methoxy-benzyloxy)-butyric acid ethyl ester
120400-77-3

(R)-3-(4-Methoxy-benzyloxy)-butyric acid ethyl ester

Conditions
ConditionsYield
With (1S)-10-camphorsulfonic acid In dichloromethane for 25h; Ambient temperature;86%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

(R)-butane-1,3-diol
6290-03-5

(R)-butane-1,3-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In diethyl ether for 1h; Ambient temperature;86%
With lithium aluminium tetrahydride In diethyl ether at 0℃; for 0.5h;85.6%
Stage #1: Ethyl (R)-3-hydroxybutanoate With lithium aluminium tetrahydride In diethyl ether at 0 - 20℃; for 3h; Inert atmosphere;
Stage #2: With water In diethyl ether
81%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

(2,6-dichloro-4-methoxyphenyl)-(2,4-dichlorophenyl)methyl trichloroacetimidate
1205121-89-6

(2,6-dichloro-4-methoxyphenyl)-(2,4-dichlorophenyl)methyl trichloroacetimidate

C20H20Cl4O4
1205122-14-0

C20H20Cl4O4

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 20℃; for 1h;85%
Ethyl (R)-3-hydroxybutanoate
24915-95-5

Ethyl (R)-3-hydroxybutanoate

magnesium (R)-3-hydroxybutyrate

magnesium (R)-3-hydroxybutyrate

Conditions
ConditionsYield
Stage #1: Ethyl (R)-3-hydroxybutanoate With sodium hydroxide In water at 10℃; for 5h;
Stage #2: With magnesium hydroxide In water for 10h;
85%

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