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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

1,4-Benzodioxane-6-carboxaldehyde Manufacturer/High quality/Best price/In stock

Cas:29668-44-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:Whit

3,4-Ethylenedioxybenzaldehyde

Cas:29668-44-8

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

1,4-Benzodioxane-6-carboxaldehyde

Cas:29668-44-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1,4-Benzodioxan-6-carboxaldehyde

Cas:29668-44-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

1,4-BENZODIOXAN-6-CARBOXALDEHYDE CAS:29668-44-8

Cas:29668-44-8

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

High qualityCAS 29668-44-8 with fast shipping

Cas:29668-44-8

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

1,4-BENZODIOXAN-6-CARBOXALDEHYDE CAS 29668-44-8

Cas:29668-44-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,4-Benzodioxane-6-carboxaldehyde 29668-44-8

Cas:29668-44-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Hanways Chempharm Co., Limited, the former is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We specialize in sourcing and supplying APIs, pharmaceutical intermediates, and fine chemicals for worldwide markets. The founder has d

For Eliglustat 1,4-Benzodioxan-6-carboxaldehyde

Cas:29668-44-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

1,4-BENZODIOXAN-6-CARBOXALDEHYDE CAS:29668-44-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

1,4-BENZODIOXAN-6-CARBOXALDEHYDE CAS:29668-44-8

Cas:29668-44-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,4-Benzodioxane-6-carboxaldehyde

Cas:29668-44-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:29668-44-8

Cas:29668-44-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

1,4-Benzodioxane-6-carboxaldehyde

Cas:29668-44-8

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1,4-Benzodioxan-6-carboxaldehyde

Cas:29668-44-8

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

2,3-Dihydrobenzo[b][1,4]dioxine-6-carbaldehyde

Cas:29668-44-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,4-Benzodioxane-6-carboxaldehyde

Cas:29668-44-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1,4-Benzodioxin-6-carboxaldehyde/High quality/Best price

Cas:29668-44-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1,4-Benzodioxan-6-carboxaldehyde

Cas:29668-44-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 1,4-BENZODIOXAN-6-CARBOXALDEHYDE Synonyms: 2,3-DIHYDRO-BENZO[1,4]DIOXINE-6-CARBALDEHYDE;2,3-DIHYDRO-1,4-BENZODIOXINE-6-CARBOXALDEHYDE;2,3-DIHYDRO-1,4-BENZODIOXINE-6-CARBALDEHYDE;2,3-DIHYDRO-1,4-BENZODIOXIN-6-CARBALDEHYDE;3,4-ETHYL

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

1,4-Benzodioxan-6-carbaldehyde

Cas:29668-44-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Cas:29668-44-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Synthetic route

ethylene dibromide
106-93-4

ethylene dibromide

3,4-dihydroxybenzaldehyde
139-85-5

3,4-dihydroxybenzaldehyde

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 70℃; for 16h;97%
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 70℃; for 16h;97%
With sodium hydroxide; tetrabutylammomium bromide In water90%
1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

3,4-dihydroxybenzaldehyde
139-85-5

3,4-dihydroxybenzaldehyde

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 105℃; for 4h;90%
With potassium carbonate In acetone at 50 - 60℃; for 29h;
9-methyl-9H-fluorene-9-carbonyl chloride
82102-37-2

9-methyl-9H-fluorene-9-carbonyl chloride

6-bromo-1,4-benzodioxane
52287-51-1

6-bromo-1,4-benzodioxane

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With dichloro(1,5-cyclooctadiene)palladium(II); N-Methyldicyclohexylamine; potassium formate; tetra-(n-butyl)ammonium iodide; tricyclohexylphosphine tetrafluoroborate; bis(dibenzylideneacetone)-palladium(0); tri tert-butylphosphoniumtetrafluoroborate at 100℃; for 18h; Reagent/catalyst; Solvent; Sealed tube; Glovebox; Inert atmosphere;81%
benzo-1,4-dioxane
493-09-4

benzo-1,4-dioxane

hexamethylenetetramine
100-97-0

hexamethylenetetramine

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
In trifluoroacetic acid at 90 - 95℃; for 24h;72%
benzo-1,4-dioxane
493-09-4

benzo-1,4-dioxane

hydrogen cyanide
74-90-8

hydrogen cyanide

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With hydrogenchloride; aluminium trichloride Zersetzung des Reaktionsprodukts durch Erhitzen mit verd. Salzsaeure;
benzo-1,4-dioxane
493-09-4

benzo-1,4-dioxane

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With N-Bromosuccinimide; n-butyllithium 1) MeOH, 2) THF, -78 deg C; Multistep reaction;
2,3-dihydro-benzo<1,4>dioxin in benzene

2,3-dihydro-benzo<1,4>dioxin in benzene

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With zinc(II) cyanide; hydrogenchloride; aluminium trichloride anschliessendes Behandeln mit wss. Salzsaeure;
ethylene dibromide
106-93-4

ethylene dibromide

disodium compound of protocatechualdehyde

disodium compound of protocatechualdehyde

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With ethanol
3,4-dihydroxybenzaldehyde
139-85-5

3,4-dihydroxybenzaldehyde

ethylene dihalide

ethylene dihalide

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide
1-benzoyl-1-<2-(hydroxy)phenoxy>ethane
78490-09-2

1-benzoyl-1-<2-(hydroxy)phenoxy>ethane

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1) AlCl3, 2) 10percent HCl / 1) benzene, temp ,40 deg C, 2) benzene, 1 h, 50 deg C
2: 48percent HBr / 15 h / Ambient temperature
3: 48 percent / NaOMe / methanol / 24 h / Heating
View Scheme

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 78 percent / NaOEt / dimethylformamide / 0.5 h / Ambient temperature
2: 1) AlCl3, 2) 10percent HCl / 1) benzene, temp ,40 deg C, 2) benzene, 1 h, 50 deg C
3: 48percent HBr / 15 h / Ambient temperature
4: 48 percent / NaOMe / methanol / 24 h / Heating
View Scheme
1-benzoil-1-<(2-idrossi-5-formil)fenossi>etano

1-benzoil-1-<(2-idrossi-5-formil)fenossi>etano

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 48percent HBr / 15 h / Ambient temperature
2: 48 percent / NaOMe / methanol / 24 h / Heating
View Scheme
benzene-1,2-diol
120-80-9

benzene-1,2-diol

1,2-bis<2-(-p-toluenesulfonyloxy)ethoxy>amine

1,2-bis<2-(-p-toluenesulfonyloxy)ethoxy>amine

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium hydroxide; water / 100 °C
2: hydrogen chloride; aluminium chloride / Zersetzung des Reaktionsprodukts durch Erhitzen mit verd. Salzsaeure
View Scheme
6-iodo-1,4-benzodioxane
57744-67-9

6-iodo-1,4-benzodioxane

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium formate; palladium diacetate; 1,2-bis-(diphenylphosphino)ethane / dimethyl sulfoxide / Inert atmosphere; Sealed tube
2: water
View Scheme
C13H17NO2

C13H17NO2

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With water
3,4-dibromobenzaldehyde
74003-55-7

3,4-dibromobenzaldehyde

ethylene glycol
107-21-1

ethylene glycol

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
With potassium carbonate; triethylamine In N,N-dimethyl-formamide at 80℃; Inert atmosphere;
vanillin
121-33-5

vanillin

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aluminum (III) chloride; pyridine / dichloromethane / 24 h / Reflux
2: potassium carbonate / N,N-dimethyl-formamide / 100 - 110 °C
View Scheme
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

ethyl acetoacetate
141-97-9

ethyl acetoacetate

α-acetyl-(2,3-dihydro-1,4-benzodioxin-6-yl)propenoic acid ethyl ester

α-acetyl-(2,3-dihydro-1,4-benzodioxin-6-yl)propenoic acid ethyl ester

Conditions
ConditionsYield
With piperidine; acetic acid In benzene for 15h; Heating;100%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

1-phenyl-3-trimethylsilylmethyl-3,4-pentadien-1-ol
312298-12-7

1-phenyl-3-trimethylsilylmethyl-3,4-pentadien-1-ol

6-((2S,6S)-3,4-Dimethylene-6-phenyl-tetrahydro-pyran-2-yl)-2,3-dihydro-benzo[1,4]dioxine

6-((2S,6S)-3,4-Dimethylene-6-phenyl-tetrahydro-pyran-2-yl)-2,3-dihydro-benzo[1,4]dioxine

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In diethyl ether at -78℃; for 4h;100%
trimethylsulphonium iodide
2181-42-2

trimethylsulphonium iodide

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

6-Oxiranyl-2,3-dihydro-benzo[1,4]dioxine
389124-25-8

6-Oxiranyl-2,3-dihydro-benzo[1,4]dioxine

Conditions
ConditionsYield
With potassium hydroxide; water In acetonitrile at 60℃; for 1.5h;100%
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

(E)-ethyl 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylate
84959-25-1

(E)-ethyl 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With lithium chloride In tetrahydrofuran at 20℃; for 0.25h; Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
Stage #2: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
Stage #2: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde In tetrahydrofuran at 20℃; for 17h; Inert atmosphere;
93%
nitromethane
75-52-5

nitromethane

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

(E)-6-(2-nitrovinyl)-2,3-dihydro[1,4]benzodioxine
10554-65-1

(E)-6-(2-nitrovinyl)-2,3-dihydro[1,4]benzodioxine

Conditions
ConditionsYield
With ammonium acetate at 100℃; Inert atmosphere;99%
With ethanol; methylamine hydrochloride; sodium carbonate
With sodium hydroxide at 15℃;
Henry reaction;
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

2,3-dihydro-1,4-benzodioxin-6-carboxylic acid
4442-54-0

2,3-dihydro-1,4-benzodioxin-6-carboxylic acid

Conditions
ConditionsYield
With sodium chlorite; sodium dihydrogen phosphate; 2-methyl-but-2-ene In water; tert-butyl alcohol at 20℃; for 45h;99%
With urea hydrogen peroxide adduct; sodium hydroxide In methanol; water for 1.5h; Reflux;81%
With potassium permanganate at 70 - 80℃; for 0.666667h;76%
1-(4-fluorophenyl)-1H-indazole-5-amine
934601-20-4

1-(4-fluorophenyl)-1H-indazole-5-amine

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(1-(4-fluorophenyl)-1H-indazol-5-yl)methanimine

1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(1-(4-fluorophenyl)-1H-indazol-5-yl)methanimine

Conditions
ConditionsYield
With magnesium sulfate In dichloromethane at 20℃; for 48h;99%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

2,3-dihydro-1,4-benzodioxin-6-carboxaldehyde-α-d1

2,3-dihydro-1,4-benzodioxin-6-carboxaldehyde-α-d1

Conditions
ConditionsYield
With 1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydro-1H-imidazolium bromide; water-d2; potassium carbonate In toluene at 40℃; for 12h;99%
With 1,3,5-triscyano-2,4,6-tris(N-carbazolyl)benzene; water-d2; sodium carbonate; triisopropylsilanethiol In ethyl acetate at 20℃; for 36h; Inert atmosphere; Sealed tube; Irradiation;91%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

malononitrile
109-77-3

malononitrile

2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methylene)malononitrile

2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methylene)malononitrile

Conditions
ConditionsYield
With nickel(II) ferrite In ethanol at 20℃; for 32h; Knoevenagel Condensation; Green chemistry;98.9%
With triethylamine In methanol Reflux;
With piperidine In ethanol at 20℃; for 2h;
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

dihydrobenzo[1,4]dioxin-6-ol
10288-72-9

dihydrobenzo[1,4]dioxin-6-ol

Conditions
ConditionsYield
With potassium fluoride; 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; Cooling with ice;98%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 50℃; for 16h;94%
Stage #1: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 50℃; for 16h;
Stage #2: With sodium hydroxide In methanol; water for 2h;
94%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

2,3-dihydrobenzo[b][1,4]dioxin-6-carbaldoxime
31127-39-6

2,3-dihydrobenzo[b][1,4]dioxin-6-carbaldoxime

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium hydroxide In ethanol at 80℃; for 4h; Inert atmosphere;98%
With hydroxylamine hydrochloride; sodium acetate In ethanol for 12h;
With hydroxylamine hydrochloride; sodium carbonate In ethanol; water at 60℃; for 1h;
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

dimethyl 2-((tertbutyldiphenylsilyl)methyl)cyclopropane-1,1-dicarboxylate
362610-79-5

dimethyl 2-((tertbutyldiphenylsilyl)methyl)cyclopropane-1,1-dicarboxylate

5-[(tert-butyl-diphenyl-silanyl)-methyl]-2-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-dihydro-furan-3,3-dicarboxylic acid dimethyl ester

5-[(tert-butyl-diphenyl-silanyl)-methyl]-2-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-dihydro-furan-3,3-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With scandium tris(trifluoromethanesulfonate) In dichloromethane at 30 - 32℃; for 6h;98%
1-methyl-2-thioxoimidazolidin-4-one
29181-65-5

1-methyl-2-thioxoimidazolidin-4-one

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

(5Z)-5-(2,3-dihydro-1,4-benzodioxan-6-ylmethylene)-1-methyl-2-thioxoimidazolidin-4-one
1334337-84-6

(5Z)-5-(2,3-dihydro-1,4-benzodioxan-6-ylmethylene)-1-methyl-2-thioxoimidazolidin-4-one

Conditions
ConditionsYield
With propylamine at 80℃; for 1h; Knoevenagel condensation; Microwave irradiation;98%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

2,3-dihydrobenzo[b][1,4]dioxine-6-carbonitrile
19102-07-9

2,3-dihydrobenzo[b][1,4]dioxine-6-carbonitrile

Conditions
ConditionsYield
With HCl·DMPU; hydroxylamine hydrochloride In acetonitrile at 60℃;98%
With oxygen; acetonitrile; copper(l) chloride In N,N-dimethyl acetamide at 130℃; for 24h; Schlenk technique;87%
With ammonia; oxygen In tert-Amyl alcohol at 40℃; under 750.075 Torr; for 24h; Green chemistry;85%
With hydroxylamine hydrochloride; sodium sulfate In N,N-dimethyl-formamide at 170℃; for 4h;81%
Multi-step reaction with 2 steps
1.1: hydroxylamine hydrochloride / methanol; water / 0.5 h / 20 °C
1.2: 20 °C
2.1: acetic anhydride / Reflux
View Scheme
4-chloro-2-hydroxy acetophenone
6921-66-0

4-chloro-2-hydroxy acetophenone

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

(E)-1-(4-chloro-2-hydroxyphenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)prop-2-en-1-one
96755-02-1

(E)-1-(4-chloro-2-hydroxyphenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)prop-2-en-1-one

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 40h; Ambient temperature;97%
With potassium hydroxide In ethanol Ambient temperature;97%
With sodium hydroxide In methanol at 20℃;37.89%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

(2,3-dihydro-benzo[1,4]dioxin-6-yl)-methanol
39270-39-8

(2,3-dihydro-benzo[1,4]dioxin-6-yl)-methanol

Conditions
ConditionsYield
Stage #1: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde With sodium tetrahydroborate In ethanol at 0 - 20℃; for 1h;
Stage #2: With water In ethanol
97%
With methanol; sodium tetrahydroborate at 0℃; for 0.5h;95%
With sodium tetrahydroborate In methanol at 25℃; for 2h;93%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

(trifluoromethyl)trimethylsilane
81290-20-2

(trifluoromethyl)trimethylsilane

1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol
923170-94-9

1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Conditions
ConditionsYield
Stage #1: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde; (trifluoromethyl)trimethylsilane With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 4h;
Stage #2: With water In N,N-dimethyl-formamide for 4h; Acidic conditions;
97%
5-Bromo-2-hydroxyacetophenone
1450-75-5

5-Bromo-2-hydroxyacetophenone

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

(E)-1-(5-bromo-2-hydroxyphenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)prop-2-en-1-one
96755-06-5

(E)-1-(5-bromo-2-hydroxyphenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)prop-2-en-1-one

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 40h; Ambient temperature;96%
With potassium hydroxide In ethanol Ambient temperature;96%
With sodium hydroxide In methanol at 20℃;58.33%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

1-(2-benzyloxy-5-fluorophenyl)-ethanone
1799-18-4

1-(2-benzyloxy-5-fluorophenyl)-ethanone

1-(2-benzyloxy-5-fluorophenyl)-3-(6-benzodioxan-1,4-yl)propenone
96755-16-7

1-(2-benzyloxy-5-fluorophenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 40h; Ambient temperature;96%
With potassium hydroxide In ethanol Ambient temperature;96%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

1-(2-(benzyloxy)-5-bromophenyl)ethanone
69822-20-4

1-(2-(benzyloxy)-5-bromophenyl)ethanone

1-(2-benzyloxy-5-bromophenyl)-3-(6-benzodioxan-1,4-yl)propenone
96755-14-5

1-(2-benzyloxy-5-bromophenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 40h; Ambient temperature;96%
With potassium hydroxide In ethanol Ambient temperature;96%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

4-methoxy-aniline
104-94-9

4-methoxy-aniline

Dimethyl phosphite
868-85-9

Dimethyl phosphite

dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(4-methoxyphenylamino)methylphosphonate
1582309-56-5

dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(4-methoxyphenylamino)methylphosphonate

Conditions
ConditionsYield
With titanium(IV) oxide In neat (no solvent) at 50℃; for 0.166667h; Green chemistry;96%
hydrogen cyanide
74-90-8

hydrogen cyanide

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-hydroxyacetonitrile

2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-hydroxyacetonitrile

Conditions
ConditionsYield
With Prunus communis hydroxynitrile lyase 5 L331A mutant In tert-butyl methyl ether at 10℃; for 12h; pH=3.5; Catalytic behavior; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;96%
With hydroxynitrile lyase isozyme 5 from Prunus communis In tert-butyl methyl ether at 25℃; for 7h; pH=5; Enzymatic reaction;84%
With (R)-oxynitrilase In di-isopropyl ether Enzymatic reaction;
1-<5-chloro-2-(phenylmethoxy)phenyl>ethanone
42972-62-3

1-<5-chloro-2-(phenylmethoxy)phenyl>ethanone

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

1-(2-benzyloxy-5-chlorophenyl)-3-(6-benzodioxan-1,4-yl)propenone
96755-15-6

1-(2-benzyloxy-5-chlorophenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water for 40h; Ambient temperature;95%
With potassium hydroxide In ethanol Ambient temperature;95%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

2-benzyloxy-4,5-dimethylacetophenone
69822-19-1

2-benzyloxy-4,5-dimethylacetophenone

1-(2-benzyloxy-4,5-dimethylphenyl)-3-(6-benzodioxan-1,4-yl)propenone
96755-18-9

1-(2-benzyloxy-4,5-dimethylphenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 40h; Ambient temperature;95%
With potassium hydroxide In ethanol Ambient temperature;95%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

C14H14O6
1267658-51-4

C14H14O6

Conditions
ConditionsYield
With piperidine; acetic acid In benzene Knoevenagel condensation;95%
With piperidine; acetic acid In benzene Dean-Stark; Reflux;
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

p-toluidine
106-49-0

p-toluidine

Dimethyl phosphite
868-85-9

Dimethyl phosphite

dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(p-tolylamino)methylphosphonate
1582309-57-6

dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(p-tolylamino)methylphosphonate

Conditions
ConditionsYield
With titanium(IV) oxide In neat (no solvent) at 50℃; for 0.2h; Green chemistry;95%
2-aminofluorene
153-78-6

2-aminofluorene

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Dimethyl phosphite
868-85-9

Dimethyl phosphite

dimethyl (((9H-fluoren-2-yl)amino)(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)phosphonate
1618086-78-4

dimethyl (((9H-fluoren-2-yl)amino)(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)phosphonate

Conditions
ConditionsYield
With polystyrene-supported p-toluenesulfonic acid In neat (no solvent) at 70℃; for 0.0833333h; Kabachnik-Fields Reaction; Microwave irradiation; Green chemistry;95%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

4-amino-1-phenylpiperazine
14340-32-0

4-amino-1-phenylpiperazine

(E)-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methylene)-4-phenylpiperazin-1-amine

(E)-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methylene)-4-phenylpiperazin-1-amine

Conditions
ConditionsYield
In toluene at 100℃;95%
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde
29668-44-8

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl 2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(hydroxy)methyl)acrylate

methyl 2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(hydroxy)methyl)acrylate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane at 30 - 40℃; Morita-Baylis-Hillman Alkylation; Sonication;95%
With 1,4-diaza-bicyclo[2.2.2]octane In methanol at 20℃; Morita-Baylis-Hillman Alkylation;

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