1,4-Benzodioxane-6-carboxaldehyde supplier

Name
1,4-BENZODIOXAN-6-CARBOXALDEHYDE
EINECS 249-763-3
CAS No. 29668-44-8
Article Data47
CAS DataBase
Density 1.262 g/cm³
Solubility
Melting Point 50-52 °C(lit.)
Formula C₉H₈O₃
Boiling Point 221.2 °C at 760 mmHg
Molecular Weight 164.161
Flash Point 116 °C
Transport Information
Appearance Yellowish-beige powder and chunks
Safety 24/25
Risk Codes
Molecular Structure
Hazard Symbols Xi
Synonyms 1,4-Benzodioxan-6-carboxaldehyde(6CI,7CI,8CI);1,4-Benzodioxane-6-aldehyde;2,3-Dihydro-1,4-benzodioxan-6-carboxaldehyde;2,3-Dihydro-1,4-benzodioxin-6-aldehyde;2,3-Dihydro-1,4-benzodioxin-6-carboxaldehyde;2,3-Dihydrobenzo[1,4]dioxine-6-carboxaldehyde;2,3-Dihydrobenzo[b][1,4]dioxine-6-carboxaldehyde;3,4-Ethylenedioxybenzaldehyde;
PSA 35.53000
LogP 1.27030

Synthetic route

: 106-93-4
ethylene dibromide

: 139-85-5
3,4-dihydroxybenzaldehyde

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 70℃; for 16h;	97%
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 70℃; for 16h;	97%
With sodium hydroxide; tetrabutylammomium bromide In water	90%

: 107-06-2
1,2-dichloro-ethane

: 139-85-5
3,4-dihydroxybenzaldehyde

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 105℃; for 4h;	90%
With potassium carbonate In acetone at 50 - 60℃; for 29h;

: 82102-37-2
9-methyl-9H-fluorene-9-carbonyl chloride

: 52287-51-1
6-bromo-1,4-benzodioxane

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With dichloro(1,5-cyclooctadiene)palladium(II); N-Methyldicyclohexylamine; potassium formate; tetra-(n-butyl)ammonium iodide; tricyclohexylphosphine tetrafluoroborate; bis(dibenzylideneacetone)-palladium(0); tri tert-butylphosphoniumtetrafluoroborate at 100℃; for 18h; Reagent/catalyst; Solvent; Sealed tube; Glovebox; Inert atmosphere;	81%

: 493-09-4
benzo-1,4-dioxane

: 100-97-0
hexamethylenetetramine

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
In trifluoroacetic acid at 90 - 95℃; for 24h;	72%

: 493-09-4
benzo-1,4-dioxane

: 74-90-8
hydrogen cyanide

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With hydrogenchloride; aluminium trichloride Zersetzung des Reaktionsprodukts durch Erhitzen mit verd. Salzsaeure;

: 493-09-4
benzo-1,4-dioxane

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With N-Bromosuccinimide; n-butyllithium 1) MeOH, 2) THF, -78 deg C; Multistep reaction;

2,3-dihydro-benzo<1,4>dioxin in benzene: 2,3-dihydro-benzo<1,4>dioxin in benzene

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With zinc(II) cyanide; hydrogenchloride; aluminium trichloride anschliessendes Behandeln mit wss. Salzsaeure;

: 106-93-4
ethylene dibromide

disodium compound of protocatechualdehyde: disodium compound of protocatechualdehyde

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With ethanol

: 139-85-5
3,4-dihydroxybenzaldehyde

ethylene dihalide: ethylene dihalide

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide

: 78490-09-2
1-benzoyl-1-<2-(hydroxy)phenoxy>ethane

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 1) AlCl3, 2) 10percent HCl / 1) benzene, temp ,40 deg C, 2) benzene, 1 h, 50 deg C 2: 48percent HBr / 15 h / Ambient temperature 3: 48 percent / NaOMe / methanol / 24 h / Heating View Scheme

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 78 percent / NaOEt / dimethylformamide / 0.5 h / Ambient temperature 2: 1) AlCl3, 2) 10percent HCl / 1) benzene, temp ,40 deg C, 2) benzene, 1 h, 50 deg C 3: 48percent HBr / 15 h / Ambient temperature 4: 48 percent / NaOMe / methanol / 24 h / Heating View Scheme

1-benzoil-1-<(2-idrossi-5-formil)fenossi>etano: 1-benzoil-1-<(2-idrossi-5-formil)fenossi>etano

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 48percent HBr / 15 h / Ambient temperature 2: 48 percent / NaOMe / methanol / 24 h / Heating View Scheme

: 120-80-9
benzene-1,2-diol

1,2-bis<2-(-p-toluenesulfonyloxy)ethoxy>amine: 1,2-bis<2-(-p-toluenesulfonyloxy)ethoxy>amine

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: potassium hydroxide; water / 100 °C 2: hydrogen chloride; aluminium chloride / Zersetzung des Reaktionsprodukts durch Erhitzen mit verd. Salzsaeure View Scheme

: 57744-67-9
6-iodo-1,4-benzodioxane

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium formate; palladium diacetate; 1,2-bis-(diphenylphosphino)ethane / dimethyl sulfoxide / Inert atmosphere; Sealed tube 2: water View Scheme

: C13H17NO2

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With water

: 74003-55-7
3,4-dibromobenzaldehyde

: 107-21-1
ethylene glycol

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
With potassium carbonate; triethylamine In N,N-dimethyl-formamide at 80℃; Inert atmosphere;

: 121-33-5
vanillin

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aluminum (III) chloride; pyridine / dichloromethane / 24 h / Reflux 2: potassium carbonate / N,N-dimethyl-formamide / 100 - 110 °C View Scheme

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 141-97-9
ethyl acetoacetate

: α-acetyl-(2,3-dihydro-1,4-benzodioxin-6-yl)propenoic acid ethyl ester

Conditions

Conditions	Yield
With piperidine; acetic acid In benzene for 15h; Heating;	100%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 312298-12-7
1-phenyl-3-trimethylsilylmethyl-3,4-pentadien-1-ol

: 6-((2S,6S)-3,4-Dimethylene-6-phenyl-tetrahydro-pyran-2-yl)-2,3-dihydro-benzo[1,4]dioxine

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate In diethyl ether at -78℃; for 4h;	100%

: 2181-42-2
trimethylsulphonium iodide

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 389124-25-8
6-Oxiranyl-2,3-dihydro-benzo[1,4]dioxine

Conditions

Conditions	Yield
With potassium hydroxide; water In acetonitrile at 60℃; for 1.5h;	100%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 84959-25-1
(E)-ethyl 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylate

Conditions

Conditions	Yield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With lithium chloride In tetrahydrofuran at 20℃; for 0.25h; Horner-Wadsworth-Emmons Olefination; Inert atmosphere; Stage #2: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran Horner-Wadsworth-Emmons Olefination; Inert atmosphere;	100%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 0℃; for 1h; Inert atmosphere; Stage #2: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde In tetrahydrofuran at 20℃; for 17h; Inert atmosphere;	93%

: 75-52-5
nitromethane

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 10554-65-1
(E)-6-(2-nitrovinyl)-2,3-dihydro[1,4]benzodioxine

Conditions

Conditions	Yield
With ammonium acetate at 100℃; Inert atmosphere;	99%
With ethanol; methylamine hydrochloride; sodium carbonate
With sodium hydroxide at 15℃;
Henry reaction;

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 4442-54-0
2,3-dihydro-1,4-benzodioxin-6-carboxylic acid

Conditions

Conditions	Yield
With sodium chlorite; sodium dihydrogen phosphate; 2-methyl-but-2-ene In water; tert-butyl alcohol at 20℃; for 45h;	99%
With urea hydrogen peroxide adduct; sodium hydroxide In methanol; water for 1.5h; Reflux;	81%
With potassium permanganate at 70 - 80℃; for 0.666667h;	76%

: 934601-20-4
1-(4-fluorophenyl)-1H-indazole-5-amine

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(1-(4-fluorophenyl)-1H-indazol-5-yl)methanimine

Conditions

Conditions	Yield
With magnesium sulfate In dichloromethane at 20℃; for 48h;	99%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 2,3-dihydro-1,4-benzodioxin-6-carboxaldehyde-α-d1

Conditions

Conditions	Yield
With 1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydro-1H-imidazolium bromide; water-d2; potassium carbonate In toluene at 40℃; for 12h;	99%
With 1,3,5-triscyano-2,4,6-tris(N-carbazolyl)benzene; water-d2; sodium carbonate; triisopropylsilanethiol In ethyl acetate at 20℃; for 36h; Inert atmosphere; Sealed tube; Irradiation;	91%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 109-77-3
malononitrile

: 2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methylene)malononitrile

Conditions

Conditions	Yield
With nickel(II) ferrite In ethanol at 20℃; for 32h; Knoevenagel Condensation; Green chemistry;	98.9%
With triethylamine In methanol Reflux;
With piperidine In ethanol at 20℃; for 2h;

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 10288-72-9
dihydrobenzo[1,4]dioxin-6-ol

Conditions

Conditions	Yield
With potassium fluoride; 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; Cooling with ice;	98%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 50℃; for 16h;	94%
Stage #1: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 50℃; for 16h; Stage #2: With sodium hydroxide In methanol; water for 2h;	94%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 31127-39-6
2,3-dihydrobenzo[b][1,4]dioxin-6-carbaldoxime

Conditions

Conditions	Yield
With hydroxylamine hydrochloride; sodium hydroxide In ethanol at 80℃; for 4h; Inert atmosphere;	98%
With hydroxylamine hydrochloride; sodium acetate In ethanol for 12h;
With hydroxylamine hydrochloride; sodium carbonate In ethanol; water at 60℃; for 1h;

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 362610-79-5
dimethyl 2-((tertbutyldiphenylsilyl)methyl)cyclopropane-1,1-dicarboxylate

: 5-[(tert-butyl-diphenyl-silanyl)-methyl]-2-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-dihydro-furan-3,3-dicarboxylic acid dimethyl ester

Conditions

Conditions	Yield
With scandium tris(trifluoromethanesulfonate) In dichloromethane at 30 - 32℃; for 6h;	98%

: 29181-65-5
1-methyl-2-thioxoimidazolidin-4-one

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 1334337-84-6
(5Z)-5-(2,3-dihydro-1,4-benzodioxan-6-ylmethylene)-1-methyl-2-thioxoimidazolidin-4-one

Conditions

Conditions	Yield
With propylamine at 80℃; for 1h; Knoevenagel condensation; Microwave irradiation;	98%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 19102-07-9
2,3-dihydrobenzo[b][1,4]dioxine-6-carbonitrile

Conditions

Conditions	Yield
With HCl·DMPU; hydroxylamine hydrochloride In acetonitrile at 60℃;	98%
With oxygen; acetonitrile; copper(l) chloride In N,N-dimethyl acetamide at 130℃; for 24h; Schlenk technique;	87%
With ammonia; oxygen In tert-Amyl alcohol at 40℃; under 750.075 Torr; for 24h; Green chemistry;	85%
With hydroxylamine hydrochloride; sodium sulfate In N,N-dimethyl-formamide at 170℃; for 4h;	81%
Multi-step reaction with 2 steps 1.1: hydroxylamine hydrochloride / methanol; water / 0.5 h / 20 °C 1.2: 20 °C 2.1: acetic anhydride / Reflux View Scheme

: 6921-66-0
4-chloro-2-hydroxy acetophenone

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 96755-02-1
(E)-1-(4-chloro-2-hydroxyphenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol for 40h; Ambient temperature;	97%
With potassium hydroxide In ethanol Ambient temperature;	97%
With sodium hydroxide In methanol at 20℃;	37.89%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 39270-39-8
(2,3-dihydro-benzo[1,4]dioxin-6-yl)-methanol

Conditions

Conditions	Yield
Stage #1: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde With sodium tetrahydroborate In ethanol at 0 - 20℃; for 1h; Stage #2: With water In ethanol	97%
With methanol; sodium tetrahydroborate at 0℃; for 0.5h;	95%
With sodium tetrahydroborate In methanol at 25℃; for 2h;	93%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 923170-94-9
1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Conditions

Conditions	Yield
Stage #1: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde; (trifluoromethyl)trimethylsilane With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 4h; Stage #2: With water In N,N-dimethyl-formamide for 4h; Acidic conditions;	97%

: 1450-75-5
5-Bromo-2-hydroxyacetophenone

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 96755-06-5
(E)-1-(5-bromo-2-hydroxyphenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol for 40h; Ambient temperature;	96%
With potassium hydroxide In ethanol Ambient temperature;	96%
With sodium hydroxide In methanol at 20℃;	58.33%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 1799-18-4
1-(2-benzyloxy-5-fluorophenyl)-ethanone

: 96755-16-7
1-(2-benzyloxy-5-fluorophenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions

Conditions	Yield
With sodium hydroxide In ethanol for 40h; Ambient temperature;	96%
With potassium hydroxide In ethanol Ambient temperature;	96%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 69822-20-4
1-(2-(benzyloxy)-5-bromophenyl)ethanone

: 96755-14-5
1-(2-benzyloxy-5-bromophenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions

Conditions	Yield
With sodium hydroxide In ethanol for 40h; Ambient temperature;	96%
With potassium hydroxide In ethanol Ambient temperature;	96%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 104-94-9
4-methoxy-aniline

: 868-85-9
Dimethyl phosphite

: 1582309-56-5
dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(4-methoxyphenylamino)methylphosphonate

Conditions

Conditions	Yield
With titanium(IV) oxide In neat (no solvent) at 50℃; for 0.166667h; Green chemistry;	96%

...Expand

: 74-90-8
hydrogen cyanide

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-hydroxyacetonitrile

Conditions

Conditions	Yield
With Prunus communis hydroxynitrile lyase 5 L331A mutant In tert-butyl methyl ether at 10℃; for 12h; pH=3.5; Catalytic behavior; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;	96%
With hydroxynitrile lyase isozyme 5 from Prunus communis In tert-butyl methyl ether at 25℃; for 7h; pH=5; Enzymatic reaction;	84%
With (R)-oxynitrilase In di-isopropyl ether Enzymatic reaction;

: 42972-62-3
1-<5-chloro-2-(phenylmethoxy)phenyl>ethanone

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 96755-15-6
1-(2-benzyloxy-5-chlorophenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water for 40h; Ambient temperature;	95%
With potassium hydroxide In ethanol Ambient temperature;	95%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 69822-19-1
2-benzyloxy-4,5-dimethylacetophenone

: 96755-18-9
1-(2-benzyloxy-4,5-dimethylphenyl)-3-(6-benzodioxan-1,4-yl)propenone

Conditions

Conditions	Yield
With sodium hydroxide In ethanol for 40h; Ambient temperature;	95%
With potassium hydroxide In ethanol Ambient temperature;	95%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 108-59-8
malonic acid dimethyl ester

: 1267658-51-4
C14H14O6

Conditions

Conditions	Yield
With piperidine; acetic acid In benzene Knoevenagel condensation;	95%
With piperidine; acetic acid In benzene Dean-Stark; Reflux;

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 106-49-0
p-toluidine

: 868-85-9
Dimethyl phosphite

: 1582309-57-6
dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(p-tolylamino)methylphosphonate

Conditions

Conditions	Yield
With titanium(IV) oxide In neat (no solvent) at 50℃; for 0.2h; Green chemistry;	95%

...Expand

: 153-78-6
2-aminofluorene

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 868-85-9
Dimethyl phosphite

: 1618086-78-4
dimethyl (((9H-fluoren-2-yl)amino)(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)phosphonate

Conditions

Conditions	Yield
With polystyrene-supported p-toluenesulfonic acid In neat (no solvent) at 70℃; for 0.0833333h; Kabachnik-Fields Reaction; Microwave irradiation; Green chemistry;	95%

...Expand

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 14340-32-0
4-amino-1-phenylpiperazine

: (E)-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methylene)-4-phenylpiperazin-1-amine

Conditions

Conditions	Yield
In toluene at 100℃;	95%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 292638-85-8
acrylic acid methyl ester

: methyl 2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(hydroxy)methyl)acrylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane at 30 - 40℃; Morita-Baylis-Hillman Alkylation; Sonication;	95%
With 1,4-diaza-bicyclo[2.2.2]octane In methanol at 20℃; Morita-Baylis-Hillman Alkylation;

1,4-Benzodioxane-6-carboxaldehyde Specification

The 1,4-Benzodioxin-6-carboxaldehyde,2,3-dihydro- is an organic compound with the formula C₉H₈O₃. It belongs to the product categories of Aromatic Aldehydes & Derivatives (substituted); Aldehydes; Benzodioxanes Carbonyl Compounds; Building Blocks; C9; Heterocyclic Building Blocks. Its EINECS registry number is 249-763-3. With the CAS registry number 29668-44-8, its IUPAC name is 2,3-dihydro-1,4-benzodioxine-6-carbaldehyde. When you are using this chemical, please be cautious about it. This chemical may cause inflammation to the skin or other mucous membranes. It is yellowish-beige powder and chunks. The product should be sealed and stored in cool, dry and well-ventilated place. What's more, it should be protected from strong oxides.

Physical properties of 1,4-Benzodioxin-6-carboxaldehyde,2,3-dihydro-: (1)ACD/LogP: 1.54; (2)#H bond acceptors: 3; (3)#Freely Rotating Bonds: 1; (4)Index of Refraction: 1.588; (5)Molar Refractivity: 43.77 cm³; (6)Molar Volume: 130 cm³; (7)Surface Tension: 51.1 dyne/cm; (8)Density: 1.262 g/cm³; (9)Flash Point: 116 °C; (10)Enthalpy of Vaporization: 45.76 kJ/mol; (11)Boiling Point: 221.2 °C at 760 mmHg; (12)Vapour Pressure: 0.109 mmHg at 25°C.

Preparation of 1,4-Benzodioxin-6-carboxaldehyde,2,3-dihydro-: this chemical can be prepared by 3,4-dihydroxy-benzaldehyde and 1,2-dibromo-ethane. This reaction will need reagent sodium hydroxide and solvent H₂O. The reaction time is 1 hour. The yield is about 50%.

1,4-Benzodioxin-6-carboxaldehyde,2,3-dihydro- can be prepared by 3,4-dihydroxy-benzaldehyde and 1,2-dibromo-ethane

Uses of 1,4-Benzodioxin-6-carboxaldehyde,2,3-dihydro-: it can be used to produce 5,10,15,20-tetrakis-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-porphyrine by heating. This reaction will need solvent propionic acid with reaction time of 1 hour. The yield is about 16.4%.

1,4-Benzodioxin-6-carboxaldehyde,2,3-dihydro- can be used to produce 5,10,15,20-tetrakis-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-porphyrine by heating

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1COC2=C(O1)C=CC(=C2)C=O
(2)InChI: InChI=1S/C9H8O3/c10-6-7-1-2-8-9(5-7)12-4-3-11-8/h1-2,5-6H,3-4H2
(3)InChIKey: CWKXDPPQCVWXAG-UHFFFAOYSA-N

Product Name

1,4-BENZODIOXAN-6-CARBOXALDEHYDE

Synthetic route

1,4-Benzodioxane-6-carboxaldehyde Specification

Related Products

Hot Products