Why Choose Us 1. Quality Price We are the manufacturer, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. Packing Products could be packaged according to customer's specializ
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inquiry300-08-3 - Physico-chemical Properties Molecular Formula C8H14BrNO2 Molar Mass 236.11 Melting Point 171-175°C Boling Point 209°C at 760 mmHg Flash Point 81.1°C Solubili
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inquiryProduct Name: Arecoline hydrobromide Synonyms: methyl-1,2,5,6-tetrahydro-1-methyl;nicotinicacid,1,2,5,6-tetrahydro-1-methyl-,methylester,hydrobromide;n-methyltetrahydronicotinicacidmethylesterhydrobromide;1-METHYL-1,2,5,6-TETRAHYDRO-3-PYRIDINECARB
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inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
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inquiryAppearance:White like crystalline powder Storage:ln stock Package:25kg/Barrel Application:It is an M and N receptor agonist, has anticholinergic effect on the central nervous system, and can also be used as a raw material for the synthesis of other
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inquiryArecoline hydrobromide CAS: 300-08-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryName Arecoline hydrobromide Synonyms Methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide Molecular Structure
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inquiryArecoline hydrobromide CAS 300-08-3 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality con
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inquiryConditions | Yield |
---|---|
With potassium carbonate In dichloromethane; water at 20℃; for 0.5h; | 100% |
With sodium carbonate pH=10 - 11; deprotonation; | |
With water; sodium carbonate for 0.5h; | |
With sodium hydroxide; water In ethyl acetate | |
With sodium carbonate In water pH=13 - 14; |
Conditions | Yield |
---|---|
In diethyl ether | 96% |
arecoline hydrobromide
benzenesulfonyl chloride
methyl 1-benzenesulfonyl-1,2,5,6-tetrahydropyridine-3-carboxylate
Conditions | Yield |
---|---|
Multistep reaction; | 90% |
Conditions | Yield |
---|---|
Stage #1: arecoline hydrobromide With sodium carbonate In water pH=10 - 11; Stage #2: With water Reflux; | 89% |
With barium dihydroxide at 40℃; for 0.5h; | |
Multi-step reaction with 2 steps 1: aq. Na2CO3 / pH 10 - 11 2: 8.2 g / water / 24 h / Heating View Scheme | |
With hydrogenchloride; water Heating / reflux; |
arecoline hydrobromide
phenylmagnesium bromide
1-Methyl-4-phenyl-piperidine-3-carboxylic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: arecoline hydrobromide With sodium hydride In toluene at -10℃; for 0.25h; Stage #2: phenylmagnesium bromide In diethyl ether; toluene at -10℃; for 1h; | 83% |
Conditions | Yield |
---|---|
In nitromethane | 77% |
arecoline hydrobromide
phenyl chloroformate
3-methoxycarbonyl-1-phenoxycarbonyl-1,2,5,6-tetrahydropyridine
Conditions | Yield |
---|---|
Stage #1: arecoline hydrobromide With sodium hydrogencarbonate Stage #2: phenyl chloroformate In dichloromethane at 0 - 20℃; for 24h; | 76% |
With sodium hydrogencarbonate In dichloromethane at 0 - 20℃; for 24h; |
Conditions | Yield |
---|---|
In nitromethane | 47% |
Conditions | Yield |
---|---|
Stage #1: arecoline hydrobromide With sodium carbonate In water Stage #2: (S,S)-hydrobenzoin With potassium tert-butylate In toluene for 16h; Reflux; Molecular sieve; stereoselective reaction; | 22% |
hydroxyguanidine hemisulfate hemihydrate
arecoline hydrobromide
3-(3-amino-1,2,4-oxadiazol-5-yl)-1-methyl-1,2,5,6-tetrahydropyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium In ethanol 1.) 20 deg C, 0.5 h, 2.) reflux, 0.5 h; | 17% |
Conditions | Yield |
---|---|
Stage #1: arecoline hydrobromide With sodium carbonate In water Stage #2: (1S,2R)-1,2-diphenylethane-1,2-diol With potassium tert-butylate In toluene for 16h; Reflux; Molecular sieve; stereoselective reaction; | 16% |
phosgene
arecoline hydrobromide
(N-chlorocarbonyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid methyl ester)
Conditions | Yield |
---|---|
In toluene |
N'-hydroxypivalimidamide
arecoline hydrobromide
5-(3-tert-Butyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
3-methoxypropionamide oxime
arecoline hydrobromide
5-[3-(2-Methoxy-ethyl)-[1,2,4]oxadiazol-5-yl]-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
hexanamide oxime
arecoline hydrobromide
1-Methyl-5-(3-pentyl-[1,2,4]oxadiazol-5-yl)-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
N'-hydroxypentanimidamide
arecoline hydrobromide
1-methyl-3-(3-butyl-1,2,4-oxadiazol-5-yl)-1,2,5,6-tetrahydropyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
isobutyramide oxime
arecoline hydrobromide
5-(3-Isopropyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
cyclopropanecarboxamide oxime
arecoline hydrobromide
5-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
N'-hydroxy-2-methoxyethanimidamide
5-(3-Methoxymethyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
5-[3-(2-Ethoxy-ethyl)-[1,2,4]oxadiazol-5-yl]-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
2-cyclopropyl-N'-hydroxyethanimidamide
5-(3-Cyclopropylmethyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
octanamide oxime
5-(3-Heptyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
n-nonanamidoxime
1-Methyl-5-(3-octyl-[1,2,4]oxadiazol-5-yl)-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
N-hydroxycyclobutanecarboxamidine
5-(3-Cyclobutyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
N-hydroxycyclopentanecarboxamidine
5-(3-Cyclopentyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
5-(3-Cycloheptyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
acetamide oxime
3-methyl-5-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,4-oxadiazole
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
N-hydroxypropanimidamide
5-(3-Ethyl-[1,2,4]oxadiazol-5-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
arecoline hydrobromide
butyramide oxime
1-Methyl-5-(3-propyl-[1,2,4]oxadiazol-5-yl)-1,2,3,6-tetrahydro-pyridine
Conditions | Yield |
---|---|
With 4 A molecular sieve; sodium 1.) ethanol, RT, 10 min, 2.) ethanol, 80 deg C, 12 h; Multistep reaction; |
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