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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2,5-Dibromo-3-picoline Manufacturer/High quality/Best price/In stock

Cas:3430-18-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,5-Dibromo-3-Methylpyridine supplier in China

Cas:3430-18-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 2,5-DIBROMO-3-METHYLPYRIDINE CAS No. 3430-18-0 Appearanc

2,5-Dibromo-3-picoline

Cas:3430-18-0

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

High quality 2,5-Dibromo-3-methylpyridine CAS 3430-18-0 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food

High quality 2,5-Dibromo-3-methylpyridine CAS 3430-18-0 with factory price

Cas:3430-18-0

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:

2,5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,5-Dibromo-3-Methylpyridine

Cas:3430-18-0

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% 2,5-Dibromo-3-picoline 3430-18-0 Producer

Cas:3430-18-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

2,5-Dibromo-3-methylpyridine Basic information Product Name: 2,5-Dibromo-3-methylpyridine Synonyms: 2,5-DIBROMO-3-METHYLPYRIDINE;2,5-DIBROMO-3-PICOLINE;TIMTEC-BB SB

2,5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 3430-18-0 with best quality

Cas:3430-18-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,5-Dibromo-3-picoline 3430-18-0

Cas:3430-18-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: 2,5-Dibromo-3-methylpyridine CAS: 3430-18-0 MF: C6H5Br2N MW: 250.92 EINECS: 608-965-5 Mol File: 3430-18-0.mol 2,5-Dibromo-3-methylpyridine Structure 2,5-Dibromo-3-methylpyridine Chemical Properties Melting point

2.5-dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2,5-Dibromo-3-methylpyridine CAS:3430-18-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

2,5-Dibromo-3-methylpyridine CAS:3430-18-0

Cas:3430-18-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,5-Dibromo-3-picoline

Cas:3430-18-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2,5-Dibromo-3-picoline/ LIDE PHARMA- Factory supply / Best price

Cas:3430-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Organic intermediate, 2,5-Dibromo-3-methylpyridine CAS:3430-18-0

Cas:3430-18-0

Min.Order:1 Gram

FOB Price: $7.2 / 8.4

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3430-18-0

Cas:3430-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,5-Dibromo-3-Methylpyridine

Cas:3430-18-0

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and quality c

2,5-Dibromo-3-picoline

Cas:3430-18-0

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2£?5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,5-Dibromo-3-picoline

Cas:3430-18-0

Min.Order:0

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Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2,5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

2,5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:1 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2,5-Dibromo-3-methylpyridine/High quality/Best price

Cas:3430-18-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,5-Dibromo-3-Methylpyridine

Cas:3430-18-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2£ 5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2,5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:0

Negotiable

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2£ 5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2£ 5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,5-Dibromo-3-methylpyridine

Cas:3430-18-0

Min.Order:0

Negotiable

Type:Manufacturers

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Synthetic route

5-bromo-3-methyl-pyridin-2-ylamine
3430-21-5

5-bromo-3-methyl-pyridin-2-ylamine

2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

Conditions
ConditionsYield
With hydrogen bromide; bromine; sodium nitrite In water at -15℃; for 3h;94%
With hydrogen bromide; bromine; sodium nitrite In water at -15 - 23℃; for 3h;94%
Stage #1: 5-bromo-3-methyl-pyridin-2-ylamine With hydrogen bromide; bromine at -15 - -10℃;
Stage #2: With sodium nitrite at 15 - 20℃; Temperature;
91.8%
3-methylpyridin-2-ylamine
1603-40-3

3-methylpyridin-2-ylamine

2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

Conditions
ConditionsYield
With hydrogen bromide; bromine; sodium nitrite 1.) bromination; 2.) water, -10 deg C, 1.5 h, 0 deg C, 0.5 h; Multistep reaction;
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; ammonium acetate / acetonitrile / 0.42 h / 20 °C / Cooling with ice
2: hydrogen bromide; bromine; sodium nitrite / water / 3 h / -15 °C
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; ammonium acetate / acetonitrile / 0.42 h / 0 - 23 °C
2: hydrogen bromide; bromine; sodium nitrite / water / 3 h / -15 - 23 °C
View Scheme
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

(R)-(+)-3-(dimethylamino)pyrrolidine

(R)-(+)-3-(dimethylamino)pyrrolidine

[(R)-1-(5-bromo-3-methyl-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine

[(R)-1-(5-bromo-3-methyl-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 100℃;99%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

dimethyl amine
124-40-3

dimethyl amine

N-(5-bromo-3-methyl-2-pyridyl)-N,N-dimethylamine

N-(5-bromo-3-methyl-2-pyridyl)-N,N-dimethylamine

Conditions
ConditionsYield
In water at 150℃; for 1h; Microwave irradiation;98%
In water at 150℃; for 1h; Microwave irradiation;98%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

5-bromo-2-iodo-3-methylpyridine
376587-52-9

5-bromo-2-iodo-3-methylpyridine

Conditions
ConditionsYield
With sodium iodide In acetyl chloride; acetonitrile for 24h; Reflux;97%
With acetyl chloride; sodium iodide In acetonitrile for 24h; Reflux;97%
With acetyl chloride; sodium iodide In acetonitrile for 16h; Reflux;94.78%
morpholine
110-91-8

morpholine

2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

4-(5-bromo-3-methylpyridin-2-yl)morpholine
566158-47-2

4-(5-bromo-3-methylpyridin-2-yl)morpholine

Conditions
ConditionsYield
at 210℃; for 0.166667h; Sealed tube; Microwave irradiation;97%
at 140℃; for 6h;
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

acetonitrile
75-05-8

acetonitrile

5-bromo-3-methyl-2-pyridineacetonitrile

5-bromo-3-methyl-2-pyridineacetonitrile

Conditions
ConditionsYield
Stage #1: acetonitrile With n-butyllithium In tetrahydrofuran at -78℃; for 0.916667h;
Stage #2: 2,5-dibromo-3-methylpyridine In tetrahydrofuran at -78 - 20℃; for 2h;
97%
Stage #1: acetonitrile With n-butyllithium In tetrahydrofuran at -78℃; for 1.5h; Inert atmosphere;
Stage #2: 2,5-dibromo-3-methylpyridine In tetrahydrofuran at 33℃; for 3h; Temperature;
86%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

benzyl alcohol
100-51-6

benzyl alcohol

2-benzyloxy-5-bromo-3-methylpyridine

2-benzyloxy-5-bromo-3-methylpyridine

Conditions
ConditionsYield
Stage #1: benzyl alcohol With sodium hydride In tetrahydrofuran for 1.5h; Reflux;
Stage #2: 2,5-dibromo-3-methylpyridine In tetrahydrofuran at 20℃; for 12h; Reflux;
95%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

sodium methylate
124-41-4

sodium methylate

2,5-dibromo-3-(methoxymethyl)pyridine

2,5-dibromo-3-(methoxymethyl)pyridine

Conditions
ConditionsYield
In methanol at 20℃; for 18h;93%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

5-bromo-2-(2-methoxy-ethoxy)-3-methyl-pyridine
1288996-83-7

5-bromo-2-(2-methoxy-ethoxy)-3-methyl-pyridine

Conditions
ConditionsYield
Stage #1: 2-methoxy-ethanol With sodium hydride In dimethyl sulfoxide; mineral oil at 20℃; for 0.5h;
Stage #2: 2,5-dibromo-3-methylpyridine In dimethyl sulfoxide; mineral oil at 60℃; for 1h;
91%
Stage #1: 2-methoxy-ethanol With sodium hydride In dimethyl sulfoxide; mineral oils at 20℃; for 0.5h;
Stage #2: 2,5-dibromo-3-methylpyridine In dimethyl sulfoxide; mineral oils at 60℃; for 1h;
91%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

2-{9H-pyrido[2,3-b]indol-9-yl}-9H-carbazole

2-{9H-pyrido[2,3-b]indol-9-yl}-9H-carbazole

9-(5-bromo-3-methylpyridin-2-yl)-2-{9H-pyrido[2,3-b]indol-9-yl}-9H-carbazole

9-(5-bromo-3-methylpyridin-2-yl)-2-{9H-pyrido[2,3-b]indol-9-yl}-9H-carbazole

Conditions
ConditionsYield
With 1-methyl-1H-imidazole; copper(l) iodide; potassium carbonate In toluene at 120℃; for 16h; Sealed tube; Inert atmosphere;90%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

sodium methylate
124-41-4

sodium methylate

5-bromo-2-methoxy-3-methylpyridine
760207-87-2

5-bromo-2-methoxy-3-methylpyridine

Conditions
ConditionsYield
In methanol at 120℃; for 0.666667h;89%
Stage #1: 2,5-dibromo-3-methylpyridine; sodium methylate In methanol at 120℃; for 0.666667h;
Stage #2: With hydrogenchloride In methanol; water at 0℃;
89%
In methanol at 100℃; for 2h; Inert atmosphere;77.8%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

Cyclopropylmethanol
2516-33-8

Cyclopropylmethanol

5-bromo-2-(cyclopropylmethoxy)-3-methylpyridine
1566224-20-1

5-bromo-2-(cyclopropylmethoxy)-3-methylpyridine

Conditions
ConditionsYield
Stage #1: Cyclopropylmethanol With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 0.333333h;
Stage #2: 2,5-dibromo-3-methylpyridine In N,N-dimethyl-formamide at 60℃;
89%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

(2R)-methylpiperazine
75336-86-6

(2R)-methylpiperazine

(R)-1-(5-bromo-3-methylpyridin-2-yl)-3-methylpiperazine
878809-59-7

(R)-1-(5-bromo-3-methylpyridin-2-yl)-3-methylpiperazine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl acetamide at 130℃; for 24h; Large scale;88%
In N,N-dimethyl acetamide at 130℃; for 16h;
In N,N-dimethyl acetamide at 130℃; for 16h; Product distribution / selectivity;
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

phenylboronic acid
98-80-6

phenylboronic acid

5-bromo-3-methyl-2-phenylpyridine
1469759-14-5

5-bromo-3-methyl-2-phenylpyridine

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; triphenylphosphine In methanol; acetonitrile at 50℃; for 24h; Suzuki Coupling; Inert atmosphere; regioselective reaction;88%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

phenylmethanethiol
100-53-8

phenylmethanethiol

2-(benzylthio)-5-bromo-3-methylpyridine

2-(benzylthio)-5-bromo-3-methylpyridine

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 20℃; for 4h;86.9%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

potassium 6-bromo-5-methylpyridin-3-yltrifluoroborate

potassium 6-bromo-5-methylpyridin-3-yltrifluoroborate

Conditions
ConditionsYield
Stage #1: 2,5-dibromo-3-methylpyridine With n-butyllithium; Triisopropyl borate In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Inert atmosphere;
Stage #2: With potassium hydrogen difluoride In tetrahydrofuran; hexane at 20℃;
85%
N-Methylformamide
123-39-7

N-Methylformamide

2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

(5-bromo-3-methylpyridin-2-yl)methylamine
245765-66-6

(5-bromo-3-methylpyridin-2-yl)methylamine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 100℃; for 3h; Temperature; Reagent/catalyst;84.2%
Stage #1: N-Methylformamide With potassium tert-butylate In N,N-dimethyl-formamide at 20 - 80℃; for 1.5h;
Stage #2: 2,5-dibromo-3-methylpyridine In N,N-dimethyl-formamide for 2h;
70.4%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

phenylacetylene
536-74-3

phenylacetylene

5-bromo-3-methyl-2-(phenylethynyl)pyridine

5-bromo-3-methyl-2-(phenylethynyl)pyridine

Conditions
ConditionsYield
With copper(l) iodide; palladium(II) trifluoroacetate; palladium diacetate; diisopropylamine In methanol; acetonitrile for 24h; Reflux; Inert atmosphere; regioselective reaction;84%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

2,3-dichlorobenzeneboronic acid
151169-74-3

2,3-dichlorobenzeneboronic acid

5-bromo-2-(2,3-dichlorophenyl)-3-methylpyridine

5-bromo-2-(2,3-dichlorophenyl)-3-methylpyridine

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; triphenylphosphine In methanol; acetonitrile at 50℃; for 24h; Inert atmosphere;81%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

carbon monoxide
201230-82-2

carbon monoxide

aniline
62-53-3

aniline

3-methyl-5-bromopyridine-2-N-phenylamide
213771-38-1

3-methyl-5-bromopyridine-2-N-phenylamide

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium diacetate In toluene; acetonitrile at 65℃; under 4137.29 Torr; for 48h; Product distribution / selectivity;76%
With triethylamine; bis-triphenylphosphine-palladium(II) chloride In acetonitrile at 60℃; under 4137.29 Torr; for 72h; Product distribution / selectivity;59%
4-morpholinecarboxaldehyde
4394-85-8

4-morpholinecarboxaldehyde

2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

6-bromo-5-methylpyridine-3-carbaldehyde
885167-81-7

6-bromo-5-methylpyridine-3-carbaldehyde

Conditions
ConditionsYield
Stage #1: 2,5-dibromo-3-methylpyridine With isopropylmagnesium chloride In tetrahydrofuran at 0 - 25℃; for 3h;
Stage #2: 4-morpholinecarboxaldehyde In tetrahydrofuran at 17 - 25℃; for 1h;
74%
Stage #1: 2,5-dibromo-3-methylpyridine With isopropylmagnesium chloride In tetrahydrofuran at 0 - 20℃; for 3h;
Stage #2: 4-morpholinecarboxaldehyde In tetrahydrofuran at 20℃; for 1h;
74%
Stage #1: 2,5-dibromo-3-methylpyridine With isopropylmagnesium chloride In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: 4-morpholinecarboxaldehyde In tetrahydrofuran at 0℃; for 2.5h;
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

copper(l) cyanide

copper(l) cyanide

5-bromo-3-methylpyridine-2-carbonitrile
156072-86-5

5-bromo-3-methylpyridine-2-carbonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 2h; Reflux;74%
In N,N-dimethyl-formamide for 2h; Reflux;74%
In water; N,N-dimethyl-formamide61.3%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

ethyl 3-[6-cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-yl]-propanoate
1415306-66-9

ethyl 3-[6-cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-yl]-propanoate

Ethyl 3-(5-bromo-2’-cyano-3-methyl-2,3’-bipyridine-5’-yl)-propanoate
1415306-74-9

Ethyl 3-(5-bromo-2’-cyano-3-methyl-2,3’-bipyridine-5’-yl)-propanoate

Conditions
ConditionsYield
With potassium phosphate; palladium diacetate; triphenylphosphine In 1,4-dioxane; water at 80℃; for 4h; Inert atmosphere;74%
Stage #1: 2,5-dibromo-3-methylpyridine With potassium phosphate; palladium diacetate; triphenylphosphine In 1,4-dioxane; water at 20℃; for 0.166667h; Suzuki Coupling; Inert atmosphere;
Stage #2: ethyl 3-[6-cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-yl]-propanoate In 1,4-dioxane; water at 80℃; for 2.5h; Suzuki Coupling; Inert atmosphere; regioselective reaction;
74%
With potassium phosphate; triphenylphosphine; palladium diacetate In 1,4-dioxane; water at 20 - 80℃; Inert atmosphere;
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

carbon monoxide
201230-82-2

carbon monoxide

N,N',N'-trimethylenediamine
142-25-6

N,N',N'-trimethylenediamine

A

5-bromo-3-methyl-pyridine-2-carboxylic acid (2-dimethylamino-ethyl)-methyl-amide

5-bromo-3-methyl-pyridine-2-carboxylic acid (2-dimethylamino-ethyl)-methyl-amide

B

C18H31N5O2

C18H31N5O2

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride In toluene; acetonitrile at 55℃; under 517.162 - 5171.62 Torr; for 6h;A 72%
B n/a
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

9-cyclopentyl-9H-pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidin-2-amine
1169698-48-9

9-cyclopentyl-9H-pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidin-2-amine

N-(5-bromo-3-methyl-2-pyridinyl)-9-cyclopentyl-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine
1169698-68-3

N-(5-bromo-3-methyl-2-pyridinyl)-9-cyclopentyl-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine

Conditions
ConditionsYield
With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 140℃; for 1h; Microwave irradiation;71%
4-phenyl-1-piperazine
92-54-6

4-phenyl-1-piperazine

2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

carbon monoxide
201230-82-2

carbon monoxide

A

C17H18BrN3O

C17H18BrN3O

B

C28H31N5O2

C28H31N5O2

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride In toluene; acetonitrile at 55℃; under 517.162 - 5171.62 Torr; for 6h;A 70%
B n/a
1-methyl-piperazine
109-01-3

1-methyl-piperazine

2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

carbon monoxide
201230-82-2

carbon monoxide

A

C12H16BrN3O

C12H16BrN3O

B

C18H27N5O2

C18H27N5O2

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride In toluene; acetonitrile at 55℃; under 517.162 - 5171.62 Torr; for 6h;A 69%
B n/a
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

5-bromo-3-picoline
3430-16-8

5-bromo-3-picoline

Conditions
ConditionsYield
With sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine In tetrahydrofuran at 25℃; for 0.5h; Inert atmosphere; regioselective reaction;68%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

carbon monoxide
201230-82-2

carbon monoxide

tert-butylamine
75-64-9

tert-butylamine

A

C16H25N3O2

C16H25N3O2

B

5-bromo-N-(tert-butyl)-3-methylpicolinamide
156072-91-2

5-bromo-N-(tert-butyl)-3-methylpicolinamide

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride In toluene; acetonitrile at 55℃; under 517.162 - 5171.62 Torr; for 6h;A n/a
B 67%
2,5-dibromo-3-methylpyridine
3430-18-0

2,5-dibromo-3-methylpyridine

2,3-dichlorobenzenethiol
17231-95-7

2,3-dichlorobenzenethiol

5-bromo-2-(2,3-dichlorophenyl)sulfanyl-3-methyl-pyridine

5-bromo-2-(2,3-dichlorophenyl)sulfanyl-3-methyl-pyridine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 25℃; Heating;67%
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