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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE

Cas:3453-00-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality diethyl (2-oxo-2-phenylethyl)phosphonate supplier in China

Cas:3453-00-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 3453-00-7 with best quality

Cas:3453-00-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE CAS3453-00-7

Cas:3453-00-7

Min.Order:1 Kilogram

FOB Price: $7.0 / 10.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester 3453-00-7

Cas:3453-00-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE CAS:3453-00-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high q

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE CAS:3453-00-7

Cas:3453-00-7

Min.Order:1 Gram

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Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality diethyl (2-oxo-2-phenylethyl)phosphonate

Cas:3453-00-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Diethyl(2-oxo-2-phenylethyl)phosphonate

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Other

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Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

4-(5-Formyl-furan-2-yl)-benzoic acid methyl ester

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

Diethyl (2-oxo-2-phenylethyl)phosphonate

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Amadis Chemical offer CAS#3453-00-7;CAT#A850200

Cas:3453-00-7

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

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Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE CAS NO.3453-00-7

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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Xiamen BaiFuchem Co.,Ltd

BaiFuChem is a Professional chemical raw material supplier in China, our main products include Biochemical , Pharma Intermediate and Organic chemical etc. BaiFuChem have wealth of products,experience , expertise and state-of-the-art

High purity diethyl (2-oxo-2-phenylethyl)phosphonate

Cas:3453-00-7

Min.Order:1 Kilogram

Negotiable

Type:Other

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Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Other

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Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Yierdechem Co. Ltd

With about ten years experiences in the field of pharmaceutical chemicals, Yierdechem has established solid business cooperation relationships with many large companys worldwide.As a leading supplier of API and pharmaceutical intermediates, holds its

Diethyl(2-oxo-2-phenylethyl)phosphonate

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Other

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Wuhan MoonZY Biological Technology Co.,Ltd

instock with good quality and wholesale price Storage:Keep in a cool & dry place Package:Packing material and QTY as your request Application:Pharma;Industry;other application Transportation:Express or as your request Port:Any port of China

DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE,3453-00-7

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Nanjing Raymon Biotech Co., Ltd.

Diethyl (2-oxo-2-phenylethyl)phosphonate Storage:Store in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/Pharmaceutical intermediates Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:S

Diethyl (2-oxo-2-phenylethyl)phosphonate

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

3453-00-7

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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pharmason ltd

99% Appearance:white Storage:BE KEPT IN TIGHT CONTAINER, PROTECT FROM LIGHT AND STORED AT A TEMPERATURE NOT EXCEEDING 20° CEL Package:5kg 10kg 20kg 25kg and more

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Chemical Co.Ltd

Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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Chemiplus Corporation

want to know more details? Please contact us

Phosphonic acid,P-(2-oxo-2-phenylethyl)-, diethyl ester

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

Diethyl (2-oxo-2-phenylethyl)phosphonate

Cas:3453-00-7

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

diethyl phenylethynylphosphonate
3450-67-7

diethyl phenylethynylphosphonate

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With 2-dicyclohexylphosphino-2’,4’,6’-triisopropylbiphenyl gold(I) bis(trifluoromethanesulfonyl)imide; water In 1,2-dichloro-ethane at 20℃; for 12h; Reagent/catalyst; Solvent; regioselective reaction;96%
With water; palladium dichloride In 1,4-dioxane at 80℃; for 2h;95%
Stage #1: diethyl phenylethynylphosphonate With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I); 2-iodophenylamine In 1,2-dichloro-ethane; toluene at 60℃; for 24h;
Stage #2: With hydrogenchloride; water In 1,2-dichloro-ethane; toluene at 20℃; for 0.25h;
94%
benzoic acid methyl ester
93-58-3

benzoic acid methyl ester

Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
Stage #1: benzoic acid methyl ester; Diethyl methylphosphonate In tetrahydrofuran at 0℃; for 0.5h; Inert atmosphere;
Stage #2: With lithium diisopropyl amide In tetrahydrofuran at 0℃; for 0.5h; Inert atmosphere;
96%
With lithium hexamethyldisilazane In tetrahydrofuran Barbier reaction; Cooling with ice; Inert atmosphere;91%
With n-butyllithium In tetrahydrofuran at -78 - 20℃;80%
Stage #1: Diethyl methylphosphonate With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: benzoic acid methyl ester In tetrahydrofuran at -78℃; for 5h;
50%
With lithium diisopropyl amide In tetrahydrofuran at -5℃; for 0.5h; Inert atmosphere;
Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

isopropyl benzoate
939-48-0

isopropyl benzoate

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran Barbier reaction; Cooling with ice; Inert atmosphere;93%
phenylacetylene
536-74-3

phenylacetylene

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

diethyl phenylethynylphosphonate
3450-67-7

diethyl phenylethynylphosphonate

B

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With tributyl-amine In dimethyl sulfoxide at 60℃; for 12h;A n/a
B 93%
(E)-3-phenylacrylic acid
140-10-3

(E)-3-phenylacrylic acid

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; oxygen In acetonitrile at 60℃; for 6h; Reagent/catalyst; Solvent; Temperature;92%
With iron(III) chloride; copper(II) bis(trifluoromethanesulfonate); triethylamine In dimethyl sulfoxide at 70℃; for 8h; Schlenk technique;78%
1-azidostyrene
16717-64-9

1-azidostyrene

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 6h; Sealed tube;92%
styrene
292638-84-7

styrene

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; oxygen In acetonitrile at 60℃; for 3h; Reagent/catalyst; Temperature; Solvent;91%
With copper(ll) sulfate pentahydrate In acetonitrile at 60℃; for 2h;91%
With di-tert-butyl peroxide; copper(II) ferrite; triethylamine In acetonitrile at 85℃; for 6h; Reagent/catalyst; Temperature; Solvent;80%
[2-(Methoxycarbonyl-hydrazono)-2-phenyl-ethyl]-phosphonic acid diethyl ester
103517-92-6

[2-(Methoxycarbonyl-hydrazono)-2-phenyl-ethyl]-phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With hydrogenchloride; acetone for 3h; Ambient temperature;90%
phenylacetylene
536-74-3

phenylacetylene

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With dipotassium peroxodisulfate; copper(ll) sulfate pentahydrate; silver nitrate In dichloromethane; water at 20℃; for 3h; Catalytic behavior; Reagent/catalyst; Solvent;89%
With iron(III) chloride; oxygen; copper(I) triflate; triethylamine In dimethyl sulfoxide at 70℃; for 24h; Reagent/catalyst; Solvent; Temperature; Concentration; Sealed tube;70%
With iron(III) chloride; copper acetylacetonate; oxygen; triethylamine In dimethyl sulfoxide at 80℃; for 24h; Reagent/catalyst; Solvent; Temperature; Concentration;63%
Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

benzoyl chloride
98-88-4

benzoyl chloride

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
Stage #1: Diethyl methylphosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h;
Stage #2: With copper(I) bromide In tetrahydrofuran; hexane at -60 - -30℃; for 1.5h;
Stage #3: benzoyl chloride In tetrahydrofuran; hexane at -40 - -30℃; Further stages.;
86%
(i) nBuLi, hexane, THF, (ii) Cu2I2, (iii) /BRN= 471389/, Et2O; Multistep reaction;
2-thiophenemethanol
636-72-6

2-thiophenemethanol

benzalacetophenone
94-41-7

benzalacetophenone

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

thiophen-2-yl-methyl benzoate
85455-66-9

thiophen-2-yl-methyl benzoate

B

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With iron(III) chloride; copper acetylacetonate; oxygen; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 90℃; for 24h; Sealed tube; chemoselective reaction;A 43%
B 86%
Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

XC(O)C6H5

XC(O)C6H5

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With n-butyllithium; lithium diisopropyl amide In tetrahydrofuran; hexane at -60℃;85%
benzalacetophenone
94-41-7

benzalacetophenone

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

benzyl alcohol
100-51-6

benzyl alcohol

A

benzoic acid benzyl ester
120-51-4

benzoic acid benzyl ester

B

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With iron(III) chloride; copper acetylacetonate; oxygen; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 90℃; for 24h; Sealed tube; chemoselective reaction;A 41%
B 85%
1-phenyl-3-dimethylaminoprop-2-enone
1201-93-0

1-phenyl-3-dimethylaminoprop-2-enone

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With manganese triacetate; acetic acid In 1,4-dioxane at 80℃; for 12h; Reagent/catalyst; Solvent; Temperature; chemoselective reaction;85%
3-(diethylamino)-1-phenylprop-2-en-1-one
3506-54-5

3-(diethylamino)-1-phenylprop-2-en-1-one

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With manganese triacetate; acetic acid In 1,4-dioxane at 80℃; for 12h; chemoselective reaction;85%
diethyl (E)-(1-(dimethylamino)-3-oxo-3-phenylprop-1-en-2-yl)-phosphonate

diethyl (E)-(1-(dimethylamino)-3-oxo-3-phenylprop-1-en-2-yl)-phosphonate

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With manganese triacetate; acetic acid In 1,4-dioxane at 80℃; for 12h; Inert atmosphere; chemoselective reaction;85%
phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

1-phenylbutan-1,3-dione
93-91-4

1-phenylbutan-1,3-dione

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With dipotassium peroxodisulfate; silver(I) acetate In water; N,N-dimethyl-formamide at 85℃; for 24h; Inert atmosphere; Schlenk technique; chemoselective reaction;84%
With manganese triacetate; acetic acid In 1,4-dioxane at 80℃; for 12h; chemoselective reaction;9%
1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With N-hydroxyphthalimide; oxygen; cobalt(II) acetate In toluene at 80℃; under 760.051 Torr; for 12h; Reagent/catalyst; Concentration; Solvent; Temperature; Schlenk technique; Sealed tube;84%
diethylphosphonoacetic acid
3095-95-2

diethylphosphonoacetic acid

benzoyl chloride
98-88-4

benzoyl chloride

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With triethylamine; magnesium chloride In acetonitrile at 20℃; for 15h; Acylation;83%
Stage #1: diethylphosphonoacetic acid With triethylamine; magnesium chloride In acetonitrile at 18℃;
Stage #2: benzoyl chloride In acetonitrile at 0 - 18℃;
55%
Yield given; Multistep reaction;
α-bromoacetophenone
70-11-1

α-bromoacetophenone

triethyl phosphite
122-52-1

triethyl phosphite

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
at 180℃; for 48h; Inert atmosphere;82%
for 4h; Reflux;68%
at 110℃; for 24h;65%
2-phenylethanol
60-12-8

2-phenylethanol

benzalacetophenone
94-41-7

benzalacetophenone

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

2-Phenylethyl benzoate
94-47-3

2-Phenylethyl benzoate

B

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With iron(III) chloride; copper acetylacetonate; oxygen; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 90℃; for 24h; Sealed tube; chemoselective reaction;A 37%
B 82%
diethyl chloromethylphosphonate
3167-63-3

diethyl chloromethylphosphonate

N-methoxy-N-methylbenzamide
6919-61-5

N-methoxy-N-methylbenzamide

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
Stage #1: diethyl chloromethylphosphonate With naphthalene; lithium In tetrahydrofuran at -78℃; Inert atmosphere;
Stage #2: N-methoxy-N-methylbenzamide In tetrahydrofuran at -78℃; for 2h; Inert atmosphere;
81%
diethyl (2-chloro-2-phenyl)vinylphosphonate
1475-83-8

diethyl (2-chloro-2-phenyl)vinylphosphonate

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With sulfuric acid80%
Multi-step reaction with 2 steps
1: H2O
View Scheme
benzy cinnamate
103-41-3

benzy cinnamate

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With iron(III) chloride; copper(I) triflate; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 90℃; for 24h; Sealed tube;80%
ethyl 3-phenyl-2-propenoate
103-36-6

ethyl 3-phenyl-2-propenoate

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With iron(III) chloride; oxygen; copper(I) triflate; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 90℃; for 24h; Reagent/catalyst; Sealed tube; Green chemistry;79%
1-naphthalene methanol
4780-79-4

1-naphthalene methanol

benzalacetophenone
94-41-7

benzalacetophenone

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

(1-naphthalenyl)methyl benzoate
17238-11-8

(1-naphthalenyl)methyl benzoate

B

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With iron(III) chloride; copper acetylacetonate; oxygen; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 90℃; for 24h; Sealed tube; chemoselective reaction;A 30%
B 78%
phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

A

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

B

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

Conditions
ConditionsYield
With iron(III) chloride; copper acetylacetonate; oxygen; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 90℃; for 24h; Sealed tube; chemoselective reaction;A 77%
B n/a
1-styrenyloxytrimethylsilane
13735-81-4

1-styrenyloxytrimethylsilane

triethyl phosphite
122-52-1

triethyl phosphite

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With iodosylbenzene; boron trifluoride diethyl etherate In dichloromethane at -40 - 20℃; for 2.5h;76%
Diethyl methylphosphonate
683-08-9

Diethyl methylphosphonate

benzoic acid ethyl ester
93-89-0

benzoic acid ethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

Conditions
ConditionsYield
With n-butyllithium at -78℃; for 2h; Inert atmosphere;75%
Stage #1: Diethyl methylphosphonate With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.166667h; Inert atmosphere;
Stage #2: benzoic acid ethyl ester In tetrahydrofuran; hexane at -78 - 22℃; for 2h; Inert atmosphere;
70%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

diethyl (1,1-difluoro-2-oxo-2-phenylethyl)phosphonate
83567-95-7

diethyl (1,1-difluoro-2-oxo-2-phenylethyl)phosphonate

Conditions
ConditionsYield
Stage #1: diethyl benzoylmethylphosphonate With potassium tert-butylate In tert-butyl alcohol at 20℃; for 0.5h;
Stage #2: With acetyl hypofluorite In tert-butyl alcohol at 20℃;
100%
With Selectfluor In acetonitrile at 80℃; for 24h;45%
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / toluene / Reflux; Dean-Stark
2: Selectfluor / acetonitrile / -10 °C
View Scheme
diiodomethane
75-11-6

diiodomethane

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

diethyl (3-oxo-3-phenylpropyl)phosphonate
16324-15-5

diethyl (3-oxo-3-phenylpropyl)phosphonate

Conditions
ConditionsYield
With diethylzinc In hexane; dichloromethane at 20℃; for 2h; chain extension;98%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

2-bromoaniline
615-36-1

2-bromoaniline

diethyl (2-((2-bromophenyl)amino)-2-phenylvinyl)phosphonate

diethyl (2-((2-bromophenyl)amino)-2-phenylvinyl)phosphonate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Reflux; Dean-Stark; Inert atmosphere;98%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

diethyl (S)-(2-hydroxy-2-phenylethyl)phosphonate
450406-75-4

diethyl (S)-(2-hydroxy-2-phenylethyl)phosphonate

Conditions
ConditionsYield
With C48H44ClO4P2Ru(1+)*Cl(1-); hydrogen In methanol at 50℃; under 7500.75 Torr; for 19h; Inert atmosphere; enantioselective reaction;97%
With hydrogen; [(R)-SYNPHOS]RuBr2 In ethanol at 50℃; under 15001.5 Torr; for 24h;
With hydrogen; ruthenium trichloride; (+)-(R)-[2,3,2',3'-tetrahydro-5,5'-bi(1,4-benzodioxin)-6,6'-diyl]bis(diphenylphosphane) In ethanol at 50℃; under 15001.5 Torr; for 64h; Conversion of starting material;n/a
With hydrogen; ruthenium trichloride; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl Conversion of starting material;n/a
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); hydrogen bromide; hydrogen; (+)-(R)-[2,3,2',3'-tetrahydro-5,5'-bi(1,4-benzodioxin)-6,6'-diyl]bis(diphenylphosphane) In ethanol at 50℃; under 15001.5 Torr; for 24h; Inert atmosphere; Autoclave;n/a
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

(Z)-(S)-diethyl (2-phenyl-2-((1-phenylethyl)amino)vinyl)phosphonate

(Z)-(S)-diethyl (2-phenyl-2-((1-phenylethyl)amino)vinyl)phosphonate

Conditions
ConditionsYield
In toluene for 12h; Dean-Stark; Reflux;97%
C21H25NO3
1160948-06-0

C21H25NO3

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

C29H31NO3

C29H31NO3

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃; for 48h; Inert atmosphere;97%
(+/-)-3,3-dimethyl-2-phenylbutanal
86429-26-7

(+/-)-3,3-dimethyl-2-phenylbutanal

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

(E)-5,5-Dimethyl-1,4-diphenyl-hex-2-en-1-one

(E)-5,5-Dimethyl-1,4-diphenyl-hex-2-en-1-one

Conditions
ConditionsYield
barium dihydroxide In 1,4-dioxane at 70℃; for 0.25h;96%
ethyl 2-amino-4H,5H,6H-cyclopentenothiophene-3-carboxylate
4815-29-6

ethyl 2-amino-4H,5H,6H-cyclopentenothiophene-3-carboxylate

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

C20H22NO4PS

C20H22NO4PS

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Reflux; Dean-Stark;96%
1-Heptylamine
111-68-2

1-Heptylamine

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

(Z)-diethyl (2-(heptylamino)-2-phenylvinyl)phosphonate

(Z)-diethyl (2-(heptylamino)-2-phenylvinyl)phosphonate

Conditions
ConditionsYield
In toluene for 12h; Dean-Stark; Reflux;96%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

5-(benzyloxy)-2,3-dihydro-3,3-dimethyl-2-hydroxy-6-(3-phenoxypropyl)benzofuran
138854-59-8

5-(benzyloxy)-2,3-dihydro-3,3-dimethyl-2-hydroxy-6-(3-phenoxypropyl)benzofuran

5-(benzyloxy)-2-(2-oxo-2-phenylethyl)-2,3-dihydro-3,3-dimethyl-6-(3-phenoxypropyl)benzofuran
139201-42-6

5-(benzyloxy)-2-(2-oxo-2-phenylethyl)-2,3-dihydro-3,3-dimethyl-6-(3-phenoxypropyl)benzofuran

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 110 - 120℃; for 2h;95%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

((Z)-1-Benzoyl-2-dimethylamino-vinyl)-phosphonic acid diethyl ester
98934-33-9

((Z)-1-Benzoyl-2-dimethylamino-vinyl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
With calcium chloride for 2h; Heating;95%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

(2-hydroxy-2-phenyl-ethyl)-phosphonic acid diethyl ester
72019-14-8

(2-hydroxy-2-phenyl-ethyl)-phosphonic acid diethyl ester

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol at 0℃;95%
Stage #1: diethyl benzoylmethylphosphonate With polymethylhydrosiloxane; P(MeNCH2CH2)3N In tetrahydrofuran at 20℃; for 12h; Reduction; hydrosilylation;
Stage #2: In tetrahydrofuran at 20℃; for 1h; Hydrolysis;
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

ethyl (phenylhydrazono)chloroacetate
28663-68-5

ethyl (phenylhydrazono)chloroacetate

ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate
17355-75-8

ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
With lithium hydroxide In 1,2-dimethoxyethane at 20℃; for 10h; Reagent/catalyst; Solvent; regioselective reaction;95%
With lithium hydroxide In 1,2-dimethoxyethane at 20℃; for 10h; Reagent/catalyst; Solvent; regioselective reaction;95%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

ethoxycarbonylformyl chloride p-bromophenylhydrazone
27143-10-8

ethoxycarbonylformyl chloride p-bromophenylhydrazone

ethyl 1-(4-bromophenyl)-5-phenyl-1H-pyrazole-3-carboxylate
62160-91-2

ethyl 1-(4-bromophenyl)-5-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
With lithium hydroxide In 1,2-dimethoxyethane at 20℃; for 10h; regioselective reaction;95%
With lithium hydroxide In 1,2-dimethoxyethane at 20℃; for 10h; regioselective reaction;95%
pyrrolidine
123-75-1

pyrrolidine

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

diethyl (2-phenyl-2-(pyrrolidin-1-yl)vinyl)phosphonate

diethyl (2-phenyl-2-(pyrrolidin-1-yl)vinyl)phosphonate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Reflux; Dean-Stark;95%
2-amino-4-benzyl-5-phenyl-thiophene-3-carbonitrile
42225-09-2

2-amino-4-benzyl-5-phenyl-thiophene-3-carbonitrile

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

C30H29N2O3PS
1443672-24-9

C30H29N2O3PS

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 72h; Reflux; Dean-Stark;94%
iodobenzene
591-50-4

iodobenzene

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

O,O-diethyl benzylphosphonate
1080-32-6

O,O-diethyl benzylphosphonate

Conditions
ConditionsYield
With [2,2]bipyridinyl; copper(II) acetate monohydrate; potassium carbonate In dimethyl sulfoxide at 110℃; for 24h; Inert atmosphere;93%
dimethyl 2-(but-2-yn-1-yl)-2-(2-oxoethyl)malonate
851388-92-6

dimethyl 2-(but-2-yn-1-yl)-2-(2-oxoethyl)malonate

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

dimethyl (E)-2-(but-2-yn-1-yl)-2-(4-oxo-4-phenylbut-2-en-1-yl)malonate

dimethyl (E)-2-(but-2-yn-1-yl)-2-(4-oxo-4-phenylbut-2-en-1-yl)malonate

Conditions
ConditionsYield
Stage #1: diethyl benzoylmethylphosphonate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: dimethyl 2-(but-2-ynyl)-2-(2-oxo-2-ethyl)malonate In tetrahydrofuran; mineral oil at 0 - 23℃; for 1h; Inert atmosphere;
93%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

C8H15IO2

C8H15IO2

C16H21O5P

C16H21O5P

Conditions
ConditionsYield
With potassium hydroxide In N,N-dimethyl-formamide at 20℃;93%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

diethyl chlorophosphate
814-49-3

diethyl chlorophosphate

[(Z)-2-(Diethoxy-phosphoryloxy)-2-phenyl-vinyl]-phosphonic acid diethyl ester
194666-43-8

[(Z)-2-(Diethoxy-phosphoryloxy)-2-phenyl-vinyl]-phosphonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: diethyl benzoylmethylphosphonate With lithium hexamethyldisilazane In tetrahydrofuran at -20℃; for 0.5h; Inert atmosphere;
Stage #2: diethyl chlorophosphate In tetrahydrofuran at -20 - 20℃; for 0.5h; Inert atmosphere;
92%
With sodium hydride 1.) THF, r.t., 2.) r.t.; Multistep reaction;
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

benzoyl chloride
98-88-4

benzoyl chloride

diethyl (1,3-dioxo-1,3-diphenylpropan-2-yl)phosphonate

diethyl (1,3-dioxo-1,3-diphenylpropan-2-yl)phosphonate

Conditions
ConditionsYield
Acylation;92%
2-chloro-2-(2-(2-methoxypyridin-5-yl)hydrazono)acetic acid ethyl ester

2-chloro-2-(2-(2-methoxypyridin-5-yl)hydrazono)acetic acid ethyl ester

diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

ethyl 1-(6-methoxypyridin-3-yl)-5-phenyl-1H-pyrazole-3-carboxylate
741286-83-9

ethyl 1-(6-methoxypyridin-3-yl)-5-phenyl-1H-pyrazole-3-carboxylate

Conditions
ConditionsYield
With lithium hydroxide In 1,2-dimethoxyethane at 20℃; for 10h; regioselective reaction;92%
With lithium hydroxide In 1,2-dimethoxyethane at 20℃; regioselective reaction;92%
diethyl benzoylmethylphosphonate
3453-00-7

diethyl benzoylmethylphosphonate

4-fluoroaniline
371-40-4

4-fluoroaniline

diethyl 2-(4-fluorophenylamino)-2-phenylvinylphosphonate

diethyl 2-(4-fluorophenylamino)-2-phenylvinylphosphonate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 24h; Reflux; Dean-Stark; Inert atmosphere;92%

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