DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:4291-63-8
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inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cladribine CAS 4291-63-8 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing th
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inquirygood quality Appearance:white powder Storage:cold storage Package:meet the demand of customer Application:diagnostic reagent Transportation:by sea or by air Port:shanghai
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
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Cas:4291-63-8
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inquiryName:Cladribine CAS NO:4291-63-8 Grade:Medical scientific research and export Molecular formula:C10H12ClN5O3 Molecular weight:285.68698 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability D
Cas:4291-63-8
Min.Order:25 Kilogram
FOB Price: $2.0 / 3.0
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inquiryProduct Name: Cladribine Synonyms: CDA;CLADRIBINE;CLADRIBINE CDA;LABOTEST-BB LT01147851;2-CHLORO-2'-DEOXYADENOSINE;2CDA;2-CL-DADO;2-chloro-2’-deoxy-adenosin CAS: 4291-63-8 MF: C10H12ClN5O3 MW: 285.69 EINECS: 636-978-6 Product Catego
Cas:4291-63-8
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:4291-63-8
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inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:4291-63-8
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inquiry1.4291-63-8 2.Cladribine 3.Good quality 4.Competitive price 5.Stock available 1.4291-63-8 2.Cladribine 3.Good quality 4.Competitive price 5.Stock available Appearance:powder Storage: Stored in a cool and dry well-closed c
Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
Cas:4291-63-8
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:4291-63-8
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inquiryProduct Name: Cladribine Synonyms: 2-CHLORO-2'-DEOXYADENOSINE;2CDA;2-CL-DADO;CDA;CLADRIBINE;CLADRIBINE CDA;LABOTEST-BB LT01147851;2-Chloro-6-amino-9-(2-deoxy-b-D-erythro-pentofuranosyl)purine CAS: 4291-63-8 MF: C10H12ClN5O3 MW: 285
Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cladribine CAS:4291-63-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,
Cas:4291-63-8
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inquiryProduct Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,
Cas:4291-63-8
Min.Order:20 Metric Ton
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inquiry1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
Cas:4291-63-8
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h
Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-
Cas:4291-63-8
Min.Order:100 Milligram
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Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
Cas:4291-63-8
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol at 60℃; for 11h; | 100% |
With ammonia In methanol at 60℃; | 59% |
2-chloro-N6,N6-dibenzoyl-3′,5′-O-dibenzoyl-2′-deoxyadenosine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol at 0 - 20℃; for 12h; | 95% |
9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-2,6-dichloropurine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol; dichloromethane at 80℃; for 7h; | 94% |
6-amino-2-chloro-9-(2'deoxy-3',5'-di-O-acetyl-β-D-erythro-pentofuranosyl)-9H-purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With sodium carbonate In methanol at 20℃; for 2h; pH=8 - 9; | 93% |
With ammonia In methanol at 0 - 20℃; | 0.62 g |
2-chloro-6-amino-9-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-β-D-ribofuranosyl]-purine
2-chloro-6-trimethylsilylamino-9-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-β-D-ribofuranosyl]-purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With sodium methylate In methanol at 20 - 30℃; for 6h; | 90% |
Conditions | Yield |
---|---|
With magnesium hydroxide; purine nucleoside phosphorylase In water at 45℃; | 88% |
9-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-2,6-dichloropurine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol; dichloromethane at 80℃; for 7h; | 87% |
2,6-Dichloro-9-(2-deoxy-3,5-di-O-p-toluoyl-β-D-erythro-pentofuranosyl)-purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol at 110℃; for 5h; Sealed tube; | 86% |
With ammonia In methanol at 100℃; for 5h; | 71% |
2-chloro-9-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-6-(2-pentylimidazol-1-yl)purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol at 60℃; for 13h; | 85% |
2-chloro-9-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-6-(2-propylimidazol-1-yl)purine
methanol
A
2-chloro-9-(2'deoxy-β-D-erythro-pentofuranosyl)-6-methoxy-9H-purine
B
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia at 40℃; for 15h; | A 85% B n/a |
9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-2-chloro-6-O-(2,4,6-triisopropylbenzenesulfonyl)purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol; dichloromethane at 80℃; for 7h; | 83% |
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol at 50℃; for 10h; | 82% |
Conditions | Yield |
---|---|
With 1A cells; E. coli BMT 4D In phosphate buffer at 65℃; for 4h; pH=7.5; | 81% |
With purine nucleoside 2’-deoxyribosyltransferase from Trypanosoma brucei immobilized on glutaraldehyde-activated MagReSynAmine microspheres In aq. phosphate buffer at 50℃; for 0.333333h; pH=6; Enzymatic reaction; |
2,6-dichloro 2’-deoxyriboside
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonium hydroxide In acetonitrile at 20℃; for 24h; | 79% |
2,6-di-chloro-9-(3',5'-di-O-p-methoxybenzoyl-2'-deoxy-D-ribofuranosyl)purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With methanol; ammonia In dichloromethane at 80℃; | 79% |
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With sodium methylate In methanol at 10 - 50℃; for 1.33333h; Heating / reflux; | 72% |
With sodium methylate In methanol at 20 - 50℃; for 0.333333h; | 72% |
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With potassium fluoride In methanol at 80℃; for 24h; | 72% |
α-D-2′-deoxyribofuranose-1-O-phosphate bis(cyclohexylammonium) salt
2-chloroadenine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With purine nucleoside phosphorylase; calcium hydroxide at 45℃; for 48h; pH=9.3; Enzymatic reaction; | 72% |
2-chloro-9-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-6-(2-pentylimidazol-1-yl)purine
A
6-amino-2-chloro-9-(2-deoxy-α-D-erythro-pentofuranosyl)purine
B
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol at 80℃; for 13h; | A n/a B 70% |
Conditions | Yield |
---|---|
With potassium dihydrogenphosphate; Escherichia coli purine nucleoside phosphorylase In aq. buffer at 20℃; for 144h; pH=7.5; Enzymatic reaction; | 70% |
Conditions | Yield |
---|---|
Stage #1: thymidine With magnesium(II) chloride hexahydrate; E. coli thymidine phosphorylase In aq. phosphate buffer at 40℃; for 120h; pH=7.20; QAE Sephadex-nPi; Stage #2: 2-chloroadenine With recombinant E. coli purine nucleoside phosphorylase In aq. phosphate buffer at 40℃; for 96h; pH=8.0; QAE Sephadex-nPi; | 59% |
With immobilized recombinant Geobacillus stearothermophilus BKM-2194 purine nucleoside phosphorylase II/pyrimidine nucleoside phosphorylase In dimethyl sulfoxide at 75℃; for 4h; pH=7.5; aq. phosphate buffer; Enzymatic reaction; | 86 %Chromat. |
With potassium phosphate; Geobacillus thermoglucosidasius purine nucleoside phosphorylase; Thermus thermophilus pyrimidine nucleoside phosphorylase In water at 70℃; for 1h; pH=7; Enzymatic reaction; |
9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-2-chloro-6-O-(6-methylbenzenesulfonyl)purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol; dichloromethane at 80℃; for 7h; | 43% |
Conditions | Yield |
---|---|
With ammonium hydroxide 1.) EtOH, DMSO, alginate gel-entrapped cells of auxotropHic thymine-dependent strain of E. coli, acetate buffer pH 5.8, 37 deg C, 16 h, 2.) room temperature, overnight; Yield given. Multistep reaction; |
2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride
2,6-dichloro-7H-purine
A
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia; sodium hydride Yield given. Multistep reaction. Yields of byproduct given; | |
Stage #1: 2,6-dichloro-7H-purine With sodium hydride In acetonitrile at 20℃; for 1.5h; Inert atmosphere; Stage #2: 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride In acetonitrile for 24.5h; Inert atmosphere; Stage #3: With ammonia In methanol at 100℃; for 6h; | A 0.4 g B 0.1 g |
9-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-2-chloro-6-O-(2,4,6-triisopropylbenzenesulfonyl)purine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonia In methanol; dichloromethane at 80℃; for 7h; |
2-Chloro-9-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-9H-purin-6-ylamine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With ammonium fluoride In methanol Heating; |
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 91 percent / purine nucleoside phosphorylase / H2O / 45 °C 2: 79 percent / aq. NH3 / acetonitrile / 24 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 95 percent / NH3 / methanol / 24 h / 160 °C 2: 88 percent / purine nucleoside phosphorylase; Mg(OH)2 / H2O / 45 °C View Scheme | |
Multi-step reaction with 6 steps 1: SnCl4 / acetonitrile / 20 °C 2: NH3 / methanol / 20 °C 3: pyridine / 20 °C 4: DMAP / acetonitrile / 20 °C 5: (Me3Si)3SiH; AIBN / dioxane / Heating 6: NH4F / methanol / Heating View Scheme | |
Multi-step reaction with 3 steps 1: 67 percent / NH3, MeOH / 12 h / 100 °C 2: 75 percent / dimethylformamide / Ambient temperature 3: 2.) aq. NH3 / 1.) EtOH, DMSO, alginate gel-entrapped cells of auxotropHic thymine-dependent strain of E. coli, acetate buffer pH 5.8, 37 deg C, 16 h, 2.) room temperature, overnight View Scheme | |
Multi-step reaction with 2 steps 1: 59 percent / 1.) NaH / acetonitrile / 1.) r.t., 30 min; 2.) 15 h 2: 71 percent / ammonia / methanol / 5 h / 100 °C View Scheme |
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 92 percent / NH3 / methanol / 24 h / 20 °C 2: 91 percent / purine nucleoside phosphorylase / H2O / 45 °C 3: 79 percent / aq. NH3 / acetonitrile / 24 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: 92 percent / NH3 / methanol / 24 h / 20 °C 2: 88 percent / purine nucleoside phosphorylase; Mg(OH)2 / H2O / 45 °C View Scheme |
acetic anhydride
2-chloro-2'-deoxyadenosine
6-amino-2-chloro-9-(2'deoxy-3',5'-di-O-acetyl-β-D-erythro-pentofuranosyl)-9H-purine
Conditions | Yield |
---|---|
With pyridine for 3h; | 92% |
With pyridine for 2h; Ambient temperature; | 81% |
2-chloro-2'-deoxyadenosine
2-azido-9-(2-deoxy-β-D-erythro-pentofuranosyl)adenine
Conditions | Yield |
---|---|
Stage #1: 2-chloro-2'-deoxyadenosine With hydrazine hydrate at 20℃; for 16h; Stage #2: With acetic acid; sodium nitrite In water for 1h; cooling; | 91% |
Multi-step reaction with 2 steps 1: H2NNH2*H2O / 20 °C 2: NaNO2; acetic acid / H2O / 0 °C View Scheme |
Conditions | Yield |
---|---|
In methanol at 130℃; for 24h; | 90% |
2-chloro-2'-deoxyadenosine
tert-butylchlorodiphenylsilane
2-chloro-9-<2-deoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-β-D-erythro-pentofuranosyl>-9H-purin-6-amine
Conditions | Yield |
---|---|
With pyridine for 14h; | 83% |
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
2-chloro-2'-deoxyadenosine
2-Chloro-9-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-9H-purin-6-ylamine
Conditions | Yield |
---|---|
With pyridine at 5 - 20℃; for 1.5h; | 83% |
2-chloro-2'-deoxyadenosine
N,N-dimethylformamide diethyl diacetal
2-chloro-9-(2'-deoxy-β-D-erythro-pentofuranosyl)-6-<<(dimethylamino)methylidene>amino>-9H-purine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide Ambient temperature; | 82% |
allyl alcohol
2-chloro-2'-deoxyadenosine
2-allyloxy-6-amino-9-[2-deoxy-β-D-erythro-pentofuranosyl]-9H-purine
Conditions | Yield |
---|---|
With sodium allyloxide at 60℃; for 2h; | 79% |
Stage #1: allyl alcohol With sodium In paraffin oil at 0℃; for 1h; Inert atmosphere; Stage #2: 2-chloro-2'-deoxyadenosine In paraffin oil at 88℃; for 12h; | 62% |
tert-butyldimethylsilyl chloride
2-chloro-2'-deoxyadenosine
5'-O-tert-butyldimethylsilylcladribine
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 20h; Inert atmosphere; | 75% |
With 1H-imidazole In pyridine at 20℃; |
Conditions | Yield |
---|---|
In methanol at 130℃; for 24h; | 75% |
Conditions | Yield |
---|---|
With pyridine; triethylamine at 0 - 20℃; for 24h; | 74% |
Conditions | Yield |
---|---|
Stage #1: benzyl alcohol With sodium In paraffin oil at 80℃; for 0.75h; Inert atmosphere; Stage #2: 2-chloro-2'-deoxyadenosine With silicon In acetonitrile; paraffin oil at 85℃; for 12h; | 71% |
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