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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

3-Methylanthranilic acid Manufacturer/High quality/Best price/In stock

Cas:4389-45-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Amino-3-Methylbenzoic Acid supplier in China

Cas:4389-45-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 4389-45-1 3-methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Almost white crystalline powder Storage:cool dry place Package:1kg/foil bag;25kg/drum Application:pharmaceutical i

Manufacturer high quality 3-Methylanthranilic acid Cas 4389-45-1 with good price

Cas:4389-45-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Amino-3-Methylbenzoic Acid

Cas:4389-45-1

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

3-Methylanthranilic Acid

Cas:4389-45-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:0

Negotiable

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Amino-m-toluic acid (COOH=1)

Cas:4389-45-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1522.html Product Name 3-Methylanthranilic acid CAS No. 4389-45-1

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2-Amino-3-methylbenzoic acid

Cas:4389-45-1

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

CAS No.4389-45-1 / 3-Methylanthranilic acid Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business r

CAS No.4389-45-1 3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 4389-45-1 with fast shipping

Cas:4389-45-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

3-Methylanthranilic acid/ LIDE PHARMA- Factory supply / Best price

Cas:4389-45-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

CAS Number 4389-45-1 Product Name 2-amino-3-methylbenzoic Acid Synonyms 3-methyl-2-amino Benzoic Acid; 3-methylanthranilic Acid;

2-Amino-3-methylbenzoic acid CAS: 4389-45-1

Cas:4389-45-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Win-Win chemical Co.Ltd

Stock products, own laboratory Appearance:Pink to gray-brown Crystalline Powder Storage:Room Temperature Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

cas no. 4389-45-1 98% 2-Amino-3-methylbenzoic acid

Cas:4389-45-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3-Methylanthranilic acid 4389-45-1

Cas:4389-45-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

3-Methylanthranilic acid CAS:4389-45-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

3-Methylanthranilic acid CAS:4389-45-1

Cas:4389-45-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 4389-45-1 3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Company information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big custo

Low Price 2-Amino-3-Methylbenzoic Acid CAS 4389-45-1

Cas:4389-45-1

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

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Lonwin Chemical Group Limited

3-Methylanthranilic Acid CAS: 4389-45-1 Specification product name 3-methylanthranilic acid cas no. 4389-45-1 appearance white powder assay ≥99% capacity 50mt/year min.

Factory supply 3-Methylanthranilic Acid

Cas:4389-45-1

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Amino-3-Methylbenzoic Acid

Cas:4389-45-1

Min.Order:0

Negotiable

Type:Manufacturers

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

2-Amino-3-methylbenzoic acid 4389-45-1 low price manufacturer

Cas:4389-45-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-Amino-2-methylbenzoic acid

Cas:4389-45-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity 3-Methylanthranilic acid

Cas:4389-45-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Synthetic route

3-methyl-2-nitrobenzoic acid
5437-38-7

3-methyl-2-nitrobenzoic acid

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol at 20℃; under 760 Torr;99%
With hydrogen; palladium on activated charcoal In ethanol at 20℃; under 25857.4 Torr;99%
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; under 760.051 Torr;99%
2-chloro-3-methylbenzoic acid
15068-35-6

2-chloro-3-methylbenzoic acid

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
With ammonia; sodium carbonate; copper(l) chloride In dimethyl sulfoxide at 130 - 150℃; for 5h;93.1%
7-methyl-1H-indole-2,3-dione
1127-59-9

7-methyl-1H-indole-2,3-dione

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide90%
With potassium chloride; dihydrogen peroxide; sodium hydroxide In water at 0 - 20℃; for 2.25h;80%
60%
3-methyl-2-nitrobenzoyl chloride
50424-93-6

3-methyl-2-nitrobenzoyl chloride

methyl 3-methyl-N-methyl-N-(3-methyl-2-aminobenzoyl)anthranilate
83325-79-5

methyl 3-methyl-N-methyl-N-(3-methyl-2-aminobenzoyl)anthranilate

A

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

B

methyl 3-methyl-N-methyl-N-<3-methyl-N-(3-methyl-2-nitrobenzoyl)anthraniloyl>anthranilate
83334-85-4

methyl 3-methyl-N-methyl-N-<3-methyl-N-(3-methyl-2-nitrobenzoyl)anthraniloyl>anthranilate

Conditions
ConditionsYield
With lithium hydroxide In water; benzeneA n/a
B 61%
8-methyl-3-o-tolyl-1H-quinazoline-2,4-dione
857203-66-8

8-methyl-3-o-tolyl-1H-quinazoline-2,4-dione

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
With potassium hydroxide
methanol
67-56-1

methanol

7-methyl-1H-indole-2,3-dione
1127-59-9

7-methyl-1H-indole-2,3-dione

A

methyl 2-amino-3-methylbenzoate
22223-49-0

methyl 2-amino-3-methylbenzoate

B

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
With dihydrogen peroxide; sodium methylate 1.) 0-10 deg C 2.) room temperature, 30 min; Yield given. Multistep reaction;
7-methyl-1H-indole-2,3-dione
1127-59-9

7-methyl-1H-indole-2,3-dione

butan-1-ol
71-36-3

butan-1-ol

A

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

B

3-Methylanthranilsaeure-n-butylester
79101-84-1

3-Methylanthranilsaeure-n-butylester

Conditions
ConditionsYield
With dihydrogen peroxide; sodium hydride 1.) 0-10 deg C 2.) room temperature, 30 min; Yield given. Multistep reaction;
3-methyl-2-nitrobenzonitrile
1885-77-4

3-methyl-2-nitrobenzonitrile

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
(i) H2, Pd-C, (ii) aq. NaOH; Multistep reaction;
3-methyl-2-nitrobenzoyl chloride
50424-93-6

3-methyl-2-nitrobenzoyl chloride

3-methyl-N-methyl-N-(3-methyl-2-aminobenzoyl)anthranilic acid
78877-00-6

3-methyl-N-methyl-N-(3-methyl-2-aminobenzoyl)anthranilic acid

A

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

B

3-methyl-N-methyl-N-<3-methyl-N-(3-methyl-2-nitrobenzoyl)anthraniloyl>anthranilic acid
83325-80-8

3-methyl-N-methyl-N-<3-methyl-N-(3-methyl-2-nitrobenzoyl)anthraniloyl>anthranilic acid

Conditions
ConditionsYield
With lithium hydroxide In water; benzene Title compound not separated from byproducts;
7-methyl-1H-indole-2,3-dione
1127-59-9

7-methyl-1H-indole-2,3-dione

dihydrogen peroxide
7722-84-1

dihydrogen peroxide

alkali

alkali

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

8-methyl-3-o-tolyl-1H-quinazoline-2,4-dione
857203-66-8

8-methyl-3-o-tolyl-1H-quinazoline-2,4-dione

aqueous NaOH

aqueous NaOH

A

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

B

o-toluidine
95-53-4

o-toluidine

3-methyl-2-nitrobenzoic acid
5437-38-7

3-methyl-2-nitrobenzoic acid

ammonia
7664-41-7

ammonia

iron(II) sulfate

iron(II) sulfate

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

hydrogenchloride
7647-01-0

hydrogenchloride

3-methyl-2-nitrobenzoic acid
5437-38-7

3-methyl-2-nitrobenzoic acid

tin

tin

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

ethanol
64-17-5

ethanol

3-methyl-2-nitrobenzoic acid
5437-38-7

3-methyl-2-nitrobenzoic acid

zinc dust

zinc dust

alkali

alkali

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

hydrogenchloride
7647-01-0

hydrogenchloride

3-methyl-2-nitrobenzoic acid
5437-38-7

3-methyl-2-nitrobenzoic acid

tin

tin

A

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

B

o-toluidine
95-53-4

o-toluidine

3-methyl-2-nitrobenzonitrile
1885-77-4

3-methyl-2-nitrobenzonitrile

alcoholic ammonium sulfide

alcoholic ammonium sulfide

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
at 100℃; im Rohr;
(2-amino-3-methyl-phenyl)-glyoxylic acid
859770-30-2

(2-amino-3-methyl-phenyl)-glyoxylic acid

dihydrogen peroxide
7722-84-1

dihydrogen peroxide

diluted NaOH-solution

diluted NaOH-solution

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

(2-amino-3-methyl-phenyl)-glyoxylic acid
859770-30-2

(2-amino-3-methyl-phenyl)-glyoxylic acid

sodium perborate

sodium perborate

diluted NaOH-solution

diluted NaOH-solution

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

m-Toluic acid
99-04-7

m-Toluic acid

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 46 percent / HNO3 / 1 h / -10 °C
2: 99 percent / H2 / Pd/C / ethanol / 20 °C / 760 Torr
View Scheme
Multi-step reaction with 2 steps
1: fuming nitric acid
2: tin; hydrochloric acid
View Scheme
Multi-step reaction with 2 steps
1: fuming nitric acid
2: tin; hydrochloric acid
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / -10 - -5 °C
2: palladium 10% on activated carbon; hydrogen / methanol
View Scheme
Multi-step reaction with 2 steps
1: nitric acid / 1 h / -10 °C
2: palladium 10% on activated carbon; hydrogen / ethanol / 2 h / 50 °C
View Scheme
m-Toluic acid
99-04-7

m-Toluic acid

aqueous ammonium polysulfide

aqueous ammonium polysulfide

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 49 percent / fuming nitric acid / 1 h / -10 °C
2: 89 percent / tin, hydrochloric acid / ethanol / 1.5 h / 70 °C
View Scheme
2-(hydroxyimino)-N-(2-methylphenyl)acetamide
1132-03-2

2-(hydroxyimino)-N-(2-methylphenyl)acetamide

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 86percent H2SO4 / 1) 55 deg C, 10 min, 2) 75 deg C, 30 min
2: H2O2, NaOH
View Scheme
Multi-step reaction with 2 steps
1: sulfuric acid / 0.33 h / 80 °C
2: dihydrogen peroxide; sodium hydroxide / water / 0 - 50 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sulfuric acid / 60 - 80 °C
2.1: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 0 - 50 °C
2.2: pH 4
View Scheme
3-Methylbenzonitrile
620-22-4

3-Methylbenzonitrile

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: concentrated hydrochloric acid / im Druckrohr
2: fuming nitric acid
3: tin; hydrochloric acid
View Scheme
3-Methyl-2-nitrobenzenecarboxamide
60310-07-8

3-Methyl-2-nitrobenzenecarboxamide

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: POCl3
2: (i) H2, Pd-C, (ii) aq. NaOH
View Scheme
o-toluidine
95-53-4

o-toluidine

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium sulfate / water / 40 °C
1.2: Reflux
2.1: sulfuric acid / 0.33 h / 80 °C
3.1: dihydrogen peroxide; sodium hydroxide / water / 0 - 50 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sodium sulfate / water / 40 °C
1.2: 0.17 h / Reflux
2.1: sulfuric acid / 60 - 80 °C
3.1: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 0 - 50 °C
3.2: pH 4
View Scheme
Multi-step reaction with 3 steps
1: hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate / water / 55 °C
2: sulfuric acid / neat (no solvent) / 55 - 80 °C
3: sodium hydroxide; dihydrogen peroxide; potassium chloride / water / 2.25 h / 0 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium sulfate; hydrogenchloride; hydroxylamine hydrochloride / water / 0.17 h / Reflux
2: sulfuric acid / 0.83 h / 70 - 80 °C
3: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 0 - 50 °C
View Scheme
Multi-step reaction with 3 steps
1: hydroxylamine hydrochloride; sodium sulfate; hydrogenchloride / water / 12 h / 55 °C / Inert atmosphere
2: sulfuric acid / 0.67 h / Heating; Inert atmosphere
3: dihydrogen peroxide; sodium hydroxide / water / 5.5 h / 80 °C / Inert atmosphere
View Scheme
3-methyl-DL-kynurenine
1446522-57-1

3-methyl-DL-kynurenine

A

L-alanin
56-41-7

L-alanin

B

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
With Pseudomonas fluorescens kynureninase In aq. phosphate buffer at 37℃; pH=8; Kinetics; Enzymatic reaction;
ethyl 7-chloroindole-3-(3-acetamido-3-carboethoxy)butanoate
582319-05-9

ethyl 7-chloroindole-3-(3-acetamido-3-carboethoxy)butanoate

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sulfuric acid / water / 2 h / 55 - 60 °C
2: ozone / methanol / 1.5 h / 785.91 Torr / Cooling with acetone-dry ice
3: hydrogenchloride / water / 4 h / Reflux
4: Pseudomonas fluorescens kynureninase / aq. phosphate buffer / 37 °C / pH 8 / Enzymatic reaction
View Scheme
ethyl 7-methylindole-3-(3-acetamido-3-carboethoxy)butanoate

ethyl 7-methylindole-3-(3-acetamido-3-carboethoxy)butanoate

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ozone / methanol / 1.5 h / 785.91 Torr / Cooling with acetone-dry ice
2: hydrogenchloride / water / 4 h / Reflux
3: Pseudomonas fluorescens kynureninase / aq. phosphate buffer / 37 °C / pH 8 / Enzymatic reaction
View Scheme
ethyl 2-acetamido-2-carboethoxy-5-oxo-5-(2-formamido-3-methylphenyl)pentanoate
1446522-63-9

ethyl 2-acetamido-2-carboethoxy-5-oxo-5-(2-formamido-3-methylphenyl)pentanoate

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride / water / 4 h / Reflux
2: Pseudomonas fluorescens kynureninase / aq. phosphate buffer / 37 °C / pH 8 / Enzymatic reaction
View Scheme
methyl 2-amino-3-methylbenzoate
22223-49-0

methyl 2-amino-3-methylbenzoate

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; ethanol; water at 50℃; for 3h; Inert atmosphere;
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-amino-3-methylbenzyl alcohol
57772-50-6

2-amino-3-methylbenzyl alcohol

Conditions
ConditionsYield
Stage #1: 3-methylantranilic acid With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 2h;
Stage #2: With water; sodium hydroxide In tetrahydrofuran
100%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 2h;100%
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; for 3.5h;97%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-amino-5-bromo-3-methylbenzoic acid
206548-13-2

2-amino-5-bromo-3-methylbenzoic acid

Conditions
ConditionsYield
With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 1h;100%
With bromine; acetic acid at 20 - 25℃;97%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 70 - 80℃; for 0.5h;95.6%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

methyl iodide
74-88-4

methyl iodide

methyl 2-amino-3-methylbenzoate
22223-49-0

methyl 2-amino-3-methylbenzoate

Conditions
ConditionsYield
Stage #1: 3-methylantranilic acid With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.666667h;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃;
100%
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 18.5h;92%
Stage #1: 3-methylantranilic acid With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: methyl iodide In N,N-dimethyl-formamide for 24h;
77%
Stage #1: 3-methylantranilic acid With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃; for 24h;
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 18h;
3-carboxyphthalic anhydride
3786-39-8

3-carboxyphthalic anhydride

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

Conditions
ConditionsYield
at 150℃; for 12h;100%
6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one
1221280-89-2

6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-amino-4-methyl-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide

2-amino-4-methyl-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide

Conditions
ConditionsYield
100%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-amino-5-chloro-3-methylbenzoic acid
20776-67-4

2-amino-5-chloro-3-methylbenzoic acid

Conditions
ConditionsYield
With chlorine In 1,2-dichloro-ethane at 50℃; for 3h; Solvent;98.1%
With N-chloro-succinimide In N,N-dimethyl-formamide at 70 - 80℃; for 0.5h;97.8%
With N-chloro-succinimide In N,N-dimethyl-formamide at 75℃;91%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

ortho-chlorobenzoic acid
118-91-2

ortho-chlorobenzoic acid

2-<(2-carboxyphenyl)amino>-3-methylbenzoic acid
80841-45-8

2-<(2-carboxyphenyl)amino>-3-methylbenzoic acid

Conditions
ConditionsYield
With copper; potassium carbonate; copper(I) bromide In various solvent(s) at 160℃; for 0.5h;98%
piperidine
110-89-4

piperidine

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

(2-amino-3-methylphenyl)(piperidin-1-yl)methanone

(2-amino-3-methylphenyl)(piperidin-1-yl)methanone

Conditions
ConditionsYield
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In N,N-dimethyl-formamide; acetonitrile at 20℃; for 16h;98%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

4-Chlorophenylsulfonyl isocyanate
5769-15-3

4-Chlorophenylsulfonyl isocyanate

3-(4-chlorobenzenesulfonyl)-8-methyl-2,4(1H,3H)-quinazolinedione

3-(4-chlorobenzenesulfonyl)-8-methyl-2,4(1H,3H)-quinazolinedione

Conditions
ConditionsYield
98%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride
129-64-6

3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride

C17H15NO4
698393-13-4

C17H15NO4

Conditions
ConditionsYield
at 110℃; for 16h; Inert atmosphere; neat (no solvent);98%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-amino-3-methylbenzamide
1885-32-1

2-amino-3-methylbenzamide

Conditions
ConditionsYield
Stage #1: 3-methylantranilic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 70℃; for 1h; Inert atmosphere;
Stage #2: With ammonium hydroxide In N,N-dimethyl-formamide
98%
Stage #1: 3-methylantranilic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 70℃; for 1h; Inert atmosphere;
Stage #2: With ammonium hydroxide In N,N-dimethyl-formamide for 16h; Inert atmosphere;
98%
Stage #1: 3-methylantranilic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 70℃; for 1h; Inert atmosphere;
Stage #2: With ammonium hydroxide In N,N-dimethyl-formamide for 16h; Inert atmosphere;
98%
p-chlorophenyl isoselenocyanate
14223-48-4

p-chlorophenyl isoselenocyanate

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-(4-chlorophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

2-(4-chlorophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 40℃; for 4.5h;98%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-amino-5-iodo-3-methylbenzoic acid
108857-24-5

2-amino-5-iodo-3-methylbenzoic acid

Conditions
ConditionsYield
With dipotassium peroxodisulfate; iodine In tetrachloromethane at 77℃; for 6h;97.7%
With N-iodo-succinimide In N,N-dimethyl-formamide at 20 - 80℃; for 2h;97%
With N-iodo-succinimide In N,N-dimethyl-formamide at 75℃; for 1h; Inert atmosphere;96%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

6,6'-dimethyl-1,1'-biphenyl-2,2'-dicarboxylic acid
57024-47-2, 108146-85-6, 19634-85-6

6,6'-dimethyl-1,1'-biphenyl-2,2'-dicarboxylic acid

Conditions
ConditionsYield
Stage #1: 3-methylantranilic acid With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.5h;
Stage #2: With copper(I) In water
97%
With Cu(I)-salt; sodium nitrite78%
Stage #1: 3-methylantranilic acid With sodium hydroxide; sodium nitrite at 0℃; for 0.5h;
Stage #2: With hydroxyammonium sulfate; copper(II) sulfate In water
72%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

[1,1'-biphenyl]-2,2'-iodonium trifluoromethanesulfonate
189999-35-7

[1,1'-biphenyl]-2,2'-iodonium trifluoromethanesulfonate

2′-iodo-[1,1′-biphenyl]-2-yl benzoate

2′-iodo-[1,1′-biphenyl]-2-yl benzoate

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; sodium carbonate In 1,4-dioxane at 95℃; for 17h; Molecular sieve; Green chemistry;97%
phosgene
75-44-5

phosgene

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

6-methylisatoic anhydride
66176-17-8

6-methylisatoic anhydride

Conditions
ConditionsYield
In 1,4-dioxane; benzene Ambient temperature;96%
With sodium hydrogencarbonate In toluene at 0 - 20℃; for 0.25h;86%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

α,α-diphenylsuccinic acid anhydride
14702-32-0

α,α-diphenylsuccinic acid anhydride

2-(2,5-dioxo-3,3-diphenylpyrrolidin-1-yl)-3-methylbenzoic acid
297757-12-1, 297757-33-6, 297757-34-7

2-(2,5-dioxo-3,3-diphenylpyrrolidin-1-yl)-3-methylbenzoic acid

Conditions
ConditionsYield
at 150℃; for 12h; Condensation;96%
at 150℃; neat (no solvent, solid phase);
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

formamidine acetic acid
3473-63-0

formamidine acetic acid

8-methyl-4-quinazolinone

8-methyl-4-quinazolinone

Conditions
ConditionsYield
In formamide at 160℃; for 12h;96%
With formamide at 160℃;96%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

1-fluoro-4-isoselenocyanatobenzene
154592-60-6

1-fluoro-4-isoselenocyanatobenzene

2-(4-fluorophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

2-(4-fluorophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 40℃; for 4.5h;96%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

cyclohexanecarbaldehyde
2043-61-0

cyclohexanecarbaldehyde

2-cyclohexyl-8-methyl-1,2-dihydro-4H-benzo[d][1,3]oxazin-4-one

2-cyclohexyl-8-methyl-1,2-dihydro-4H-benzo[d][1,3]oxazin-4-one

Conditions
ConditionsYield
With acetic acid In ethanol for 6h; Reflux;96%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

6-methylisatoic anhydride
66176-17-8

6-methylisatoic anhydride

Conditions
ConditionsYield
In 1,4-dioxane for 6.5h; Reflux;95%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; dichloromethane94%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; dichloromethane94%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

1,2-cis-cyclohexanedicarboxylic anhydride
13149-00-3

1,2-cis-cyclohexanedicarboxylic anhydride

C16H17NO4
1185155-84-3

C16H17NO4

Conditions
ConditionsYield
at 110℃; for 10h; Inert atmosphere; neat (no solvent);95%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

4-bromophenyl isoselenocyanate
147695-56-5

4-bromophenyl isoselenocyanate

2-(4-bromophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

2-(4-bromophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 40℃; for 4.5h;95%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

2-amino-5-bromo-3-methylbenzoic acid hydrobromide

2-amino-5-bromo-3-methylbenzoic acid hydrobromide

Conditions
ConditionsYield
With bromine; acetic acid In dichloromethane at 20℃; for 1h;95%
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

acetic anhydride
108-24-7

acetic anhydride

2-acetylamino-3-methylbenzoic acid
67081-69-0

2-acetylamino-3-methylbenzoic acid

Conditions
ConditionsYield
for 2h; Reflux;94%
for 2h; Heating;87%
for 1h; Acetylation; Heating;85%
at 60℃; Reflux;
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

6-methylisatoic anhydride
66176-17-8

6-methylisatoic anhydride

Conditions
ConditionsYield
With bis(trichloromethyl) carbonate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; dichloromethane at 20℃; for 16.5h;94%
Multi-step reaction with 2 steps
1: triethylamine; dmap / acetonitrile / 2 h / 20 °C
2: 2-chloro-1-methyl-pyridinium iodide / acetonitrile / 0.17 h / 20 °C
View Scheme
3-methylantranilic acid
4389-45-1

3-methylantranilic acid

formamidine acetic acid
3473-63-0

formamidine acetic acid

8-methylquinazolin-4(3H)-one
19181-54-5

8-methylquinazolin-4(3H)-one

Conditions
ConditionsYield
at 180℃; for 3h;94%
4-pentynoic acid
6089-09-4

4-pentynoic acid

3-methylantranilic acid
4389-45-1

3-methylantranilic acid

3a,9-dimethyl-3,3a-dihydro-1H-benzo[d]pyrrolo[2,1-b][1,3]-oxazine-1,5(2H)-dione
1227624-59-0

3a,9-dimethyl-3,3a-dihydro-1H-benzo[d]pyrrolo[2,1-b][1,3]-oxazine-1,5(2H)-dione

Conditions
ConditionsYield
With Echavarren's catalyst In 1,1-dichloroethane at 120℃; for 12h; Sealed vial;93%
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