3-Methylanthranilic acid supplier

Name
3-Methylanthranilic acid
EINECS 224-505-2
CAS No. 4389-45-1
Article Data51
CAS DataBase
Density 1.254 g/cm³
Solubility
Melting Point 174-177 °C(lit.)
Formula C₈H₉NO₂
Boiling Point 315.1 °C at 760 mmHg
Molecular Weight 151.165
Flash Point 144.4 °C
Transport Information
Appearance pink to grey-brown crystalline powder
Safety 24/25-36-26
Risk Codes 22-36/37/38
Molecular Structure
Hazard Symbols Xn, Xi
Synonyms m-Toluicacid, 2-amino- (6CI,7CI,8CI);2-Amino-3-methylbenzoic acid;2-Amino-m-toluicacid;3-Methyl-2-aminobenzoic acid;
PSA 63.32000
LogP 1.85660

Synthetic route

: 5437-38-7
3-methyl-2-nitrobenzoic acid

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol at 20℃; under 760 Torr;	99%
With hydrogen; palladium on activated charcoal In ethanol at 20℃; under 25857.4 Torr;	99%
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; under 760.051 Torr;	99%

: 15068-35-6
2-chloro-3-methylbenzoic acid

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
With ammonia; sodium carbonate; copper(l) chloride In dimethyl sulfoxide at 130 - 150℃; for 5h;	93.1%

: 1127-59-9
7-methyl-1H-indole-2,3-dione

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
With sodium hydroxide; dihydrogen peroxide	90%
With potassium chloride; dihydrogen peroxide; sodium hydroxide In water at 0 - 20℃; for 2.25h;	80%
	60%

: 50424-93-6
3-methyl-2-nitrobenzoyl chloride

: 83325-79-5
methyl 3-methyl-N-methyl-N-(3-methyl-2-aminobenzoyl)anthranilate

A: 4389-45-1
3-methylantranilic acid

B: 83334-85-4
methyl 3-methyl-N-methyl-N-<3-methyl-N-(3-methyl-2-nitrobenzoyl)anthraniloyl>anthranilate

Conditions

Conditions	Yield
With lithium hydroxide In water; benzene	A n/a B 61%

...Expand

: 857203-66-8
8-methyl-3-o-tolyl-1H-quinazoline-2,4-dione

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
With potassium hydroxide

: 67-56-1
methanol

: 1127-59-9
7-methyl-1H-indole-2,3-dione

A: 22223-49-0
methyl 2-amino-3-methylbenzoate

B: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; sodium methylate 1.) 0-10 deg C 2.) room temperature, 30 min; Yield given. Multistep reaction;

...Expand

: 1127-59-9
7-methyl-1H-indole-2,3-dione

: 71-36-3
butan-1-ol

A: 4389-45-1
3-methylantranilic acid

B: 79101-84-1
3-Methylanthranilsaeure-n-butylester

Conditions

Conditions	Yield
With dihydrogen peroxide; sodium hydride 1.) 0-10 deg C 2.) room temperature, 30 min; Yield given. Multistep reaction;

...Expand

: 1885-77-4
3-methyl-2-nitrobenzonitrile

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
(i) H2, Pd-C, (ii) aq. NaOH; Multistep reaction;

: 50424-93-6
3-methyl-2-nitrobenzoyl chloride

: 78877-00-6
3-methyl-N-methyl-N-(3-methyl-2-aminobenzoyl)anthranilic acid

A: 4389-45-1
3-methylantranilic acid

B: 83325-80-8
3-methyl-N-methyl-N-<3-methyl-N-(3-methyl-2-nitrobenzoyl)anthraniloyl>anthranilic acid

Conditions

Conditions	Yield
With lithium hydroxide In water; benzene Title compound not separated from byproducts;

...Expand

: 1127-59-9
7-methyl-1H-indole-2,3-dione

: 7722-84-1
dihydrogen peroxide

alkali: alkali

: 4389-45-1
3-methylantranilic acid

...Expand

: 857203-66-8
8-methyl-3-o-tolyl-1H-quinazoline-2,4-dione

aqueous NaOH: aqueous NaOH

A: 4389-45-1
3-methylantranilic acid

B: 95-53-4
o-toluidine

...Expand

: 5437-38-7
3-methyl-2-nitrobenzoic acid

: 7664-41-7
ammonia

: iron(II) sulfate

: 4389-45-1
3-methylantranilic acid

...Expand

: 7647-01-0
hydrogenchloride

: 5437-38-7
3-methyl-2-nitrobenzoic acid

tin: tin

: 4389-45-1
3-methylantranilic acid

...Expand

: 64-17-5
ethanol

: 5437-38-7
3-methyl-2-nitrobenzoic acid

zinc dust: zinc dust

alkali: alkali

: 4389-45-1
3-methylantranilic acid

...Expand

: 7647-01-0
hydrogenchloride

: 5437-38-7
3-methyl-2-nitrobenzoic acid

tin: tin

A: 4389-45-1
3-methylantranilic acid

B: 95-53-4
o-toluidine

...Expand

: 1885-77-4
3-methyl-2-nitrobenzonitrile

alcoholic ammonium sulfide: alcoholic ammonium sulfide

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
at 100℃; im Rohr;

: 859770-30-2
(2-amino-3-methyl-phenyl)-glyoxylic acid

: 7722-84-1
dihydrogen peroxide

diluted NaOH-solution: diluted NaOH-solution

: 4389-45-1
3-methylantranilic acid

...Expand

: 859770-30-2
(2-amino-3-methyl-phenyl)-glyoxylic acid

sodium perborate: sodium perborate

diluted NaOH-solution: diluted NaOH-solution

: 4389-45-1
3-methylantranilic acid

...Expand

: 99-04-7
m-Toluic acid

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 46 percent / HNO3 / 1 h / -10 °C 2: 99 percent / H2 / Pd/C / ethanol / 20 °C / 760 Torr View Scheme
Multi-step reaction with 2 steps 1: fuming nitric acid 2: tin; hydrochloric acid View Scheme
Multi-step reaction with 2 steps 1: fuming nitric acid 2: tin; hydrochloric acid View Scheme
Multi-step reaction with 2 steps 1: nitric acid / -10 - -5 °C 2: palladium 10% on activated carbon; hydrogen / methanol View Scheme
Multi-step reaction with 2 steps 1: nitric acid / 1 h / -10 °C 2: palladium 10% on activated carbon; hydrogen / ethanol / 2 h / 50 °C View Scheme

: 99-04-7
m-Toluic acid

aqueous ammonium polysulfide: aqueous ammonium polysulfide

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 49 percent / fuming nitric acid / 1 h / -10 °C 2: 89 percent / tin, hydrochloric acid / ethanol / 1.5 h / 70 °C View Scheme

: 1132-03-2
2-(hydroxyimino)-N-(2-methylphenyl)acetamide

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 86percent H2SO4 / 1) 55 deg C, 10 min, 2) 75 deg C, 30 min 2: H2O2, NaOH View Scheme
Multi-step reaction with 2 steps 1: sulfuric acid / 0.33 h / 80 °C 2: dihydrogen peroxide; sodium hydroxide / water / 0 - 50 °C View Scheme
Multi-step reaction with 2 steps 1.1: sulfuric acid / 60 - 80 °C 2.1: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 0 - 50 °C 2.2: pH 4 View Scheme

: 620-22-4
3-Methylbenzonitrile

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: concentrated hydrochloric acid / im Druckrohr 2: fuming nitric acid 3: tin; hydrochloric acid View Scheme

: 60310-07-8
3-Methyl-2-nitrobenzenecarboxamide

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: POCl3 2: (i) H2, Pd-C, (ii) aq. NaOH View Scheme

: 95-53-4
o-toluidine

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: sodium sulfate / water / 40 °C 1.2: Reflux 2.1: sulfuric acid / 0.33 h / 80 °C 3.1: dihydrogen peroxide; sodium hydroxide / water / 0 - 50 °C View Scheme
Multi-step reaction with 3 steps 1.1: sodium sulfate / water / 40 °C 1.2: 0.17 h / Reflux 2.1: sulfuric acid / 60 - 80 °C 3.1: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 0 - 50 °C 3.2: pH 4 View Scheme
Multi-step reaction with 3 steps 1: hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate / water / 55 °C 2: sulfuric acid / neat (no solvent) / 55 - 80 °C 3: sodium hydroxide; dihydrogen peroxide; potassium chloride / water / 2.25 h / 0 - 20 °C View Scheme
Multi-step reaction with 3 steps 1: sodium sulfate; hydrogenchloride; hydroxylamine hydrochloride / water / 0.17 h / Reflux 2: sulfuric acid / 0.83 h / 70 - 80 °C 3: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 0 - 50 °C View Scheme
Multi-step reaction with 3 steps 1: hydroxylamine hydrochloride; sodium sulfate; hydrogenchloride / water / 12 h / 55 °C / Inert atmosphere 2: sulfuric acid / 0.67 h / Heating; Inert atmosphere 3: dihydrogen peroxide; sodium hydroxide / water / 5.5 h / 80 °C / Inert atmosphere View Scheme

: 1446522-57-1
3-methyl-DL-kynurenine

A: 56-41-7
L-alanin

B: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
With Pseudomonas fluorescens kynureninase In aq. phosphate buffer at 37℃; pH=8; Kinetics; Enzymatic reaction;

: 582319-05-9
ethyl 7-chloroindole-3-(3-acetamido-3-carboethoxy)butanoate

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: sulfuric acid / water / 2 h / 55 - 60 °C 2: ozone / methanol / 1.5 h / 785.91 Torr / Cooling with acetone-dry ice 3: hydrogenchloride / water / 4 h / Reflux 4: Pseudomonas fluorescens kynureninase / aq. phosphate buffer / 37 °C / pH 8 / Enzymatic reaction View Scheme

: ethyl 7-methylindole-3-(3-acetamido-3-carboethoxy)butanoate

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: ozone / methanol / 1.5 h / 785.91 Torr / Cooling with acetone-dry ice 2: hydrogenchloride / water / 4 h / Reflux 3: Pseudomonas fluorescens kynureninase / aq. phosphate buffer / 37 °C / pH 8 / Enzymatic reaction View Scheme

: 1446522-63-9
ethyl 2-acetamido-2-carboethoxy-5-oxo-5-(2-formamido-3-methylphenyl)pentanoate

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride / water / 4 h / Reflux 2: Pseudomonas fluorescens kynureninase / aq. phosphate buffer / 37 °C / pH 8 / Enzymatic reaction View Scheme

: 22223-49-0
methyl 2-amino-3-methylbenzoate

: 4389-45-1
3-methylantranilic acid

Conditions

Conditions	Yield
With sodium hydroxide In tetrahydrofuran; ethanol; water at 50℃; for 3h; Inert atmosphere;

: 4389-45-1
3-methylantranilic acid

: 57772-50-6
2-amino-3-methylbenzyl alcohol

Conditions

Conditions	Yield
Stage #1: 3-methylantranilic acid With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 2h; Stage #2: With water; sodium hydroxide In tetrahydrofuran	100%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 2h;	100%
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; for 3.5h;	97%

: 4389-45-1
3-methylantranilic acid

: 206548-13-2
2-amino-5-bromo-3-methylbenzoic acid

Conditions

Conditions	Yield
With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 1h;	100%
With bromine; acetic acid at 20 - 25℃;	97%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 70 - 80℃; for 0.5h;	95.6%

: 4389-45-1
3-methylantranilic acid

: 74-88-4
methyl iodide

: 22223-49-0
methyl 2-amino-3-methylbenzoate

Conditions

Conditions	Yield
Stage #1: 3-methylantranilic acid With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.666667h; Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃;	100%
With caesium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 18.5h;	92%
Stage #1: 3-methylantranilic acid With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: methyl iodide In N,N-dimethyl-formamide for 24h;	77%
Stage #1: 3-methylantranilic acid With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃; for 24h;
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 18h;

: 3786-39-8
3-carboxyphthalic anhydride

: 4389-45-1
3-methylantranilic acid

: 1158834-44-6, 1159266-95-1, 1159266-96-2
C17H11NO6

Conditions

Conditions	Yield
at 150℃; for 12h;	100%

: 1221280-89-2
6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one

: 4389-45-1
3-methylantranilic acid

: 2-amino-4-methyl-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide

Conditions

Conditions	Yield
	100%

: 4389-45-1
3-methylantranilic acid

: 20776-67-4
2-amino-5-chloro-3-methylbenzoic acid

Conditions

Conditions	Yield
With chlorine In 1,2-dichloro-ethane at 50℃; for 3h; Solvent;	98.1%
With N-chloro-succinimide In N,N-dimethyl-formamide at 70 - 80℃; for 0.5h;	97.8%
With N-chloro-succinimide In N,N-dimethyl-formamide at 75℃;	91%

: 4389-45-1
3-methylantranilic acid

: 118-91-2
ortho-chlorobenzoic acid

: 80841-45-8
2-<(2-carboxyphenyl)amino>-3-methylbenzoic acid

Conditions

Conditions	Yield
With copper; potassium carbonate; copper(I) bromide In various solvent(s) at 160℃; for 0.5h;	98%

: 110-89-4
piperidine

: 4389-45-1
3-methylantranilic acid

: (2-amino-3-methylphenyl)(piperidin-1-yl)methanone

Conditions

Conditions	Yield
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In N,N-dimethyl-formamide; acetonitrile at 20℃; for 16h;	98%

: 4389-45-1
3-methylantranilic acid

: 5769-15-3
4-Chlorophenylsulfonyl isocyanate

: 3-(4-chlorobenzenesulfonyl)-8-methyl-2,4(1H,3H)-quinazolinedione

Conditions

Conditions	Yield
	98%

: 4389-45-1
3-methylantranilic acid

: 129-64-6
3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride

: 698393-13-4
C17H15NO4

Conditions

Conditions	Yield
at 110℃; for 16h; Inert atmosphere; neat (no solvent);	98%

: 4389-45-1
3-methylantranilic acid

: 1885-32-1
2-amino-3-methylbenzamide

Conditions

Conditions	Yield
Stage #1: 3-methylantranilic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 70℃; for 1h; Inert atmosphere; Stage #2: With ammonium hydroxide In N,N-dimethyl-formamide	98%
Stage #1: 3-methylantranilic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 70℃; for 1h; Inert atmosphere; Stage #2: With ammonium hydroxide In N,N-dimethyl-formamide for 16h; Inert atmosphere;	98%
Stage #1: 3-methylantranilic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 70℃; for 1h; Inert atmosphere; Stage #2: With ammonium hydroxide In N,N-dimethyl-formamide for 16h; Inert atmosphere;	98%

: 14223-48-4
p-chlorophenyl isoselenocyanate

: 4389-45-1
3-methylantranilic acid

: 2-(4-chlorophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 40℃; for 4.5h;	98%

: 4389-45-1
3-methylantranilic acid

: 108857-24-5
2-amino-5-iodo-3-methylbenzoic acid

Conditions

Conditions	Yield
With dipotassium peroxodisulfate; iodine In tetrachloromethane at 77℃; for 6h;	97.7%
With N-iodo-succinimide In N,N-dimethyl-formamide at 20 - 80℃; for 2h;	97%
With N-iodo-succinimide In N,N-dimethyl-formamide at 75℃; for 1h; Inert atmosphere;	96%

: 4389-45-1
3-methylantranilic acid

: 57024-47-2, 108146-85-6, 19634-85-6
6,6'-dimethyl-1,1'-biphenyl-2,2'-dicarboxylic acid

Conditions

Conditions	Yield
Stage #1: 3-methylantranilic acid With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.5h; Stage #2: With copper(I) In water	97%
With Cu(I)-salt; sodium nitrite	78%
Stage #1: 3-methylantranilic acid With sodium hydroxide; sodium nitrite at 0℃; for 0.5h; Stage #2: With hydroxyammonium sulfate; copper(II) sulfate In water	72%

: 4389-45-1
3-methylantranilic acid

: 189999-35-7
[1,1'-biphenyl]-2,2'-iodonium trifluoromethanesulfonate

: 2′-iodo-[1,1′-biphenyl]-2-yl benzoate

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline; sodium carbonate In 1,4-dioxane at 95℃; for 17h; Molecular sieve; Green chemistry;	97%

: 75-44-5
phosgene

: 4389-45-1
3-methylantranilic acid

: 66176-17-8
6-methylisatoic anhydride

Conditions

Conditions	Yield
In 1,4-dioxane; benzene Ambient temperature;	96%
With sodium hydrogencarbonate In toluene at 0 - 20℃; for 0.25h;	86%

: 4389-45-1
3-methylantranilic acid

: 14702-32-0
α,α-diphenylsuccinic acid anhydride

: 297757-12-1, 297757-33-6, 297757-34-7
2-(2,5-dioxo-3,3-diphenylpyrrolidin-1-yl)-3-methylbenzoic acid

Conditions

Conditions	Yield
at 150℃; for 12h; Condensation;	96%
at 150℃; neat (no solvent, solid phase);

: 4389-45-1
3-methylantranilic acid

: 3473-63-0
formamidine acetic acid

: 8-methyl-4-quinazolinone

Conditions

Conditions	Yield
In formamide at 160℃; for 12h;	96%
With formamide at 160℃;	96%

: 4389-45-1
3-methylantranilic acid

: 154592-60-6
1-fluoro-4-isoselenocyanatobenzene

: 2-(4-fluorophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 40℃; for 4.5h;	96%

: 4389-45-1
3-methylantranilic acid

: 2043-61-0
cyclohexanecarbaldehyde

: 2-cyclohexyl-8-methyl-1,2-dihydro-4H-benzo[d][1,3]oxazin-4-one

Conditions

Conditions	Yield
With acetic acid In ethanol for 6h; Reflux;	96%

: 32315-10-9
bis(trichloromethyl) carbonate

: 4389-45-1
3-methylantranilic acid

: 66176-17-8
6-methylisatoic anhydride

Conditions

Conditions	Yield
In 1,4-dioxane for 6.5h; Reflux;	95%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; dichloromethane	94%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; dichloromethane	94%

: 4389-45-1
3-methylantranilic acid

: 13149-00-3
1,2-cis-cyclohexanedicarboxylic anhydride

: 1185155-84-3
C16H17NO4

Conditions

Conditions	Yield
at 110℃; for 10h; Inert atmosphere; neat (no solvent);	95%

: 4389-45-1
3-methylantranilic acid

: 147695-56-5
4-bromophenyl isoselenocyanate

: 2-(4-bromophenylamino)-8-methyl-4H-benzo[d][1,3]oxazin-4-one

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 40℃; for 4.5h;	95%

: 4389-45-1
3-methylantranilic acid

: 2-amino-5-bromo-3-methylbenzoic acid hydrobromide

Conditions

Conditions	Yield
With bromine; acetic acid In dichloromethane at 20℃; for 1h;	95%

: 4389-45-1
3-methylantranilic acid

: 108-24-7
acetic anhydride

: 67081-69-0
2-acetylamino-3-methylbenzoic acid

Conditions

Conditions	Yield
for 2h; Reflux;	94%
for 2h; Heating;	87%
for 1h; Acetylation; Heating;	85%
at 60℃; Reflux;

: 4389-45-1
3-methylantranilic acid

: 66176-17-8
6-methylisatoic anhydride

Conditions

Conditions	Yield
With bis(trichloromethyl) carbonate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; dichloromethane at 20℃; for 16.5h;	94%
Multi-step reaction with 2 steps 1: triethylamine; dmap / acetonitrile / 2 h / 20 °C 2: 2-chloro-1-methyl-pyridinium iodide / acetonitrile / 0.17 h / 20 °C View Scheme

: 4389-45-1
3-methylantranilic acid

: 3473-63-0
formamidine acetic acid

: 77287-34-4, 77287-35-5, 60100-09-6
formamide

: 19181-54-5
8-methylquinazolin-4(3H)-one

Conditions

Conditions	Yield
at 180℃; for 3h;	94%

...Expand

: 6089-09-4
4-pentynoic acid

: 4389-45-1
3-methylantranilic acid

: 1227624-59-0
3a,9-dimethyl-3,3a-dihydro-1H-benzo[d]pyrrolo[2,1-b][1,3]-oxazine-1,5(2H)-dione

Conditions

Conditions	Yield
With Echavarren's catalyst In 1,1-dichloroethane at 120℃; for 12h; Sealed vial;	93%

3-Methylanthranilic acid Chemical Properties

IUPAC Name: 2-Amino-3-methylbenzoic acid
Synonyms of 3-Methylanthranilic acid (CAS NO.4389-45-1): 2-Amino-3-methylbenzoic acid ; 3-Methyl-2-aminobenzoic acid ; Benzoic acid, 2-amino-3-methyl- (9CI) ; m-Toluic acid, 2-amino- (8CI)
CAS NO: 4389-45-1
Molecular Formula: C₈H₉NO₂
Molecular Weight: 151.16
Molecular Structure:

H bond acceptors: 3
H bond donors: 3
Freely Rotating Bonds: 2
Polar Surface Area: 29.54 Å²
Index of Refraction: 1.618
Molar Refractivity: 42.24 cm³
Molar Volume: 120.5 cm³
Surface Tension: 58.2 dyne/cm
Density: 1.254 g/cm³
Flash Point: 144.4 °C
Enthalpy of Vaporization: 58.74 kJ/mol
Boiling Point: 315.1 °C at 760 mmHg
Vapour Pressure: 0.000188 mmHg at 25°C
Melting Point: 174-177 °C(lit.)
Appearance: pink to grey-brown crystalline powder
Product Categories of 3-Methylanthranilic acid (CAS NO.4389-45-1): CARBOXYLICACID;FINE Chemical & INTERMEDIATES;Amines;blocks;Carboxes;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid;Organic acids;Carboxylic Acids;Phenyls & Phenyl-Het

3-Methylanthranilic acid Uses

3-Methylanthranilic acid (CAS NO.4389-45-1) is used as intermediates in organic synthesis.

3-Methylanthranilic acid Safety Profile

Safety Information about 3-Methylanthranilic acid (CAS NO.4389-45-1):
Hazard Codes: Harmful Xn,Xi
Risk Statements: 22-36/37/38
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26
S24/25: Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
WGK Germany: 3
F: 10
Hazard Note: Irritant
HazardClass: IRRITANT

3-Methylanthranilic acid Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Keep container closed when not in use.

Product Name

3-Methylanthranilic acid

Synthetic route

3-Methylanthranilic acid Chemical Properties

3-Methylanthranilic acid Uses

3-Methylanthranilic acid Safety Profile

3-Methylanthranilic acid Specification

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