Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:443-69-6
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inquiryItems Standard Result Assay 98%min ----------------------------------------------------------------------------------------------
Cas:443-69-6
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inquiry1, Full experience of large numbers containers loading in main Chinese seaports 2, Packing with pallet as buyer's special request 3, Best service after shipment with e-mail 4, Cargoes together with container sales service ava
Cas:443-69-6
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inquiryGood quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai
High quality. Factory supply. In stock. Best price. 1.Quick response within 24 hours; 2.Best quality in your requirement; 3.We pay more attention on delivery time, and usually ship on time; 4.Under the premise of safety and effectiveness, we can pr
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inquiryColorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Product Description Product website: http://www.finerchem.com/pro01en/id/788.html Product Name
Cas:443-69-6
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inquiry5-Fluoroisatin Basic information Product Name: 5-Fluoroisatin Synonyms: BUTTPARK 24\07-36;AKOS BBS-00006537;5-FLUOROINDOLINE-2,3-DIONE;5-FLUOROISATIN;5-FLUOROISATINE;5-FLUOROINDOLE-2
With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:443-69-6
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:443-69-6
Min.Order:10 Kilogram
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiry5-Fluoroisatin Chemical Properties Melting point 224-227 °C (lit.) density 1.477±0.06 g/cm3(Predicted) storage temp. Refrigerator pka 8.51±0.20(Predicted) form Powder color Red BRN 131241 InChIKey GKODD
Cas:443-69-6
Min.Order:1 Gram
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:443-69-6
Min.Order:25 Gram
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inquiry5-Fluoroisatin CAS:443-69-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
Cas:443-69-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
Cas:443-69-6
Min.Order:1 Kilogram
FOB Price: $160.0 / 200.0
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
product name 5-fluoroisatin synonyms 5-fluoroindoline-2,3-dione cas no. 443-69-6 molecular weight 165.12 molecular formula c8h4fno2 melting point 224-227 ºc appeara
Cas:443-69-6
Min.Order:1 Kilogram
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inquiryAppearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:443-69-6
Min.Order:0 Metric Ton
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:443-69-6
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:443-69-6
Min.Order:100 Gram
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inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Conditions | Yield |
---|---|
With sulfuric acid In water at 80℃; for 0.333333h; | 88.6% |
With sulfuric acid In water at 50 - 75℃; Temperature; | 88.2% |
With sulfuric acid at 20℃; | 85% |
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With sulfuric acid at 50 - 75℃; for 0.333333h; | 88.2% |
Conditions | Yield |
---|---|
With iodine pentoxide In dimethyl sulfoxide at 80℃; | 87% |
With o-iodosobenzoic acid; oxygen In dimethyl sulfoxide at 80℃; for 12h; Green chemistry; | 72% |
3-(4-fluorophenylimino)-5-fluoro-N-(4-fluorophenyl)-3H-indole-2-amine
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With hydrogenchloride; acetic acid In water for 0.333333h; Reflux; | 85% |
5-fluoroindol-2(3H)-one
A
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With oxygen; sodium iodide In tetrahydrofuran at 60℃; for 12h; Schlenk technique; chemoselective reaction; | A 80% B 8% |
carbon monoxide
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
Stage #1: N'-(2-bromo-4-fluorophenyl)-N,N-dimethylurea With methyllithium In tetrahydrofuran; diethyl ether at 0℃; Stage #2: With tert.-butyl lithium In tetrahydrofuran; diethyl ether; n-heptane at 0℃; for 1h; Stage #3: carbon monoxide In tetrahydrofuran; diethyl ether; n-heptane at 0℃; for 0.5h; | 79% |
Yield given; Multistep reaction; |
Conditions | Yield |
---|---|
In acetonitrile at 60℃; for 16h; | 78.7% |
Conditions | Yield |
---|---|
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; oxygen In acetonitrile at 20℃; for 18h; | 68% |
Conditions | Yield |
---|---|
Stage #1: chloral hydrate; 4-fluoroaniline With hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate In water Stage #2: With sulfuric acid at 60 - 80℃; | 63% |
Stage #1: chloral hydrate; 4-fluoroaniline With hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate for 0.166667h; Heating; Stage #2: With sulfuric acid for 1h; Heating; | |
Stage #1: chloral hydrate; 4-fluoroaniline With hydroxylamine hydrochloride; sodium sulfate In water Sandmeyer reaction; Stage #2: With sulfuric acid In methanol Sandmeyer reaction; |
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With sulfuric acid 1) 50 deg C, 30 min; 2) 80 deg C, 10 min; | 62% |
Conditions | Yield |
---|---|
Stage #1: chloral ethyl hemiacetal; 4-fluoroaniline With hydrogenchloride; sodium sulfate In water for 1h; Stage #2: With hydroxylamine hydrochloride In water at 10 - 80℃; for 1.5h; Stage #3: With sulfuric acid at 60℃; for 6h; | 61% |
(E)-N-(4-fluorophenyl)-2-(hydroxyimino)acetamide
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With sulfuric acid In water at 50 - 90℃; | 52% |
With sulfuric acid In water at 50 - 90℃; | 52% |
5-fluoroindol-2(3H)-one
A
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With oxygen; sodium iodide In dimethyl sulfoxide at 100℃; for 12h; Schlenk technique; chemoselective reaction; | A 29% B 52% |
Conditions | Yield |
---|---|
With H-β zeolite In 1,2-dichloro-ethane at 80℃; for 36h; Inert atmosphere; | 51% |
3,3-dibromo-5-fluoro-2-oxindole
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With water In methanol for 2h; Heating; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydroxylamine sulfate; sodium sulfate; HCl / ethanol; H2O 2: H2SO4 View Scheme | |
Multi-step reaction with 2 steps 1: 91 percent / NH2OH*HCl; sodium sulfate / H2O / 0.05 h / microwave irradiation 2: 61 percent / H2SO4 (86 percent) / 0.01 h / microwave irradiation View Scheme | |
Multi-step reaction with 2 steps 1: NH2OH 2: conc. H2SO4 / Heating View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: Et3N / tetrahydrofuran / 2 h / 0 °C 1.2: 71 percent / tetrahydrofuran / 1 h / 0 °C 2.1: MeLi / tetrahydrofuran; diethyl ether / 0 °C 2.2: t-BuLi / tetrahydrofuran; diethyl ether; heptane / 1 h / 0 °C 2.3: 79 percent / tetrahydrofuran; diethyl ether; heptane / 0.5 h / 0 °C View Scheme |
5-fluoroindol-2(3H)-one
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: CuBr2 / ethyl acetate / 80 °C 2: water / methanol / 2 h / Heating View Scheme | |
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; oxygen In acetonitrile at 20℃; for 24h; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NH2OH*HCl, Na2SO4 2: H2SO4 View Scheme |
5-iodoisatin
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
Stage #1: 5-iodoisatin With tetrakis(triphenylphosphine) palladium(0); bis(tri-n-butyltin); lithium chloride In 1,4-dioxane at 23 - 100℃; Inert atmosphere; Stage #2: With silver trifluoromethanesulfonate; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(hexafluorophosphate) In acetone at 23℃; for 0.333333h; Inert atmosphere; regiospecific reaction; | 11.9 mg |
C8H5FN2O
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With sulfuric acid; water |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogenchloride; sulfuric acid; sodium sulfate; hydroxylamine hydrochloride / water / 100 °C 2: sulfuric acid / 85 °C View Scheme |
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 140℃; Microwave irradiation; | 100% |
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile at 20℃; | 100% |
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile at 20℃; | 100% |
5-fluoro-1H-indole-2,3-dione
5-fluoro-1-n-propylisatin
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile at 20℃; | 100% |
Conditions | Yield |
---|---|
With caesium carbonate In acetonitrile at 20℃; | 100% |
5-fluoro-1H-indole-2,3-dione
5-fluoroindol-2(3H)-one
Conditions | Yield |
---|---|
With hydrazine hydrate In water at 140℃; for 6h; Temperature; Wolff-Kishner-Huang Minlon Reduction; | 99.1% |
With titanium tetrachloride; zinc In tetrahydrofuran at 20℃; for 0.1h; Inert atmosphere; | 87% |
Stage #1: 5-fluoro-1H-indole-2,3-dione With potassium hydroxide; hydrazine In ethylene glycol at 80℃; for 3h; Stage #2: With hydrogenchloride; water In ethylene glycol at 0 - 20℃; for 12h; pH=1 - 2; | 81.9% |
5-fluoro-1H-indole-2,3-dione
3,3'-methylenedianiline
Conditions | Yield |
---|---|
In water at 20℃; for 22h; | 99% |
With acetic acid In ethanol for 5h; Heating; | 68% |
In ethanol Heating; |
indole
5-fluoro-1H-indole-2,3-dione
5'-fluoro-1H,1''H-[3,3':3',3''-terindol]-2'(1'H)-one
Conditions | Yield |
---|---|
With titanium(IV) oxide In water at 20℃; Green chemistry; | 99% |
With bromine In acetonitrile at 20℃; for 7h; | 92% |
With C14H32N2O6S2(2+)*2ClO4(1-) In neat (no solvent) at 110℃; for 0.166667h; Catalytic behavior; Reagent/catalyst; | 89% |
5-fluoro-1H-indole-2,3-dione
3-(trifluoromethyl)propiophenone
6-fluoro-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid
Conditions | Yield |
---|---|
Stage #1: 5-fluoro-1H-indole-2,3-dione; 3-(trifluoromethyl)propiophenone With potassium hydroxide In ethanol; water for 1h; Reflux; Stage #2: With hydrogenchloride In water pH=~ 3; Product distribution / selectivity; | 99% |
Stage #1: 5-fluoro-1H-indole-2,3-dione With potassium hydroxide In ethanol; water for 0.25h; Stage #2: 3-(trifluoromethyl)propiophenone In ethanol; water for 1h; Reflux; Stage #3: With hydrogenchloride In water pH=6; | 34% |
5-fluoro-1H-indole-2,3-dione
aminomalonic acid diethyl ester
dimethyl acetylenedicarboxylate
5',5'-diethyl 3',4'-dimethyl 5-fluoro-2-oxospiro[indoline-3,2'-pyrrole]-3',4',5',5'(1'H)-tetracarboxylate
Conditions | Yield |
---|---|
With trifluoroacetic acid In 1,2-dichloro-ethane at 60℃; for 36h; Time; Molecular sieve; | 99% |
Conditions | Yield |
---|---|
With water at 20℃; for 12h; | 99% |
Conditions | Yield |
---|---|
With water at 20℃; for 12h; | 99% |
Conditions | Yield |
---|---|
With water at 20℃; for 24h; | 99% |
Conditions | Yield |
---|---|
With water at 20℃; for 24h; | 99% |
Conditions | Yield |
---|---|
With water at 20℃; for 24h; | 99% |
Conditions | Yield |
---|---|
With water at 20℃; for 0.166667h; Green chemistry; | 99% |
5-fluoro-1H-indole-2,3-dione
5-propyl-2,4-dihydro-3H-pyrazol-3-one
Conditions | Yield |
---|---|
With water at 20℃; for 0.166667h; Green chemistry; | 99% |
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With 1-[3,5-bis(trifluoromethyl)phenyl]-3-[(1S,2S)-2-(dimethylamino)cyclohexyl]thiourea In acetonitrile at 25℃; for 12h; enantioselective reaction; | 99% |
1-(pyridin-2-yl)-butan-2-one
5-fluoro-1H-indole-2,3-dione
2-ethyl-6-fluoro-3-(pyridin-2-yl)quinoline-4-carboxylic acid
Conditions | Yield |
---|---|
With potassium hydroxide In ethanol; water at 90℃; | 99% |
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With methanol; triethylamine at 20℃; for 24h; | 99% |
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
With hydrazine hydrate In methanol at 20℃; for 12.5h; Reflux; | 98.3% |
5-fluoro-1H-indole-2,3-dione
2-oxo-propionic acid
6-fluoroquinoline-2,4-dicarboxylic acid
Conditions | Yield |
---|---|
With sodium hydroxide at 110℃; for 6h; | 98.15% |
With sodium hydroxide at 110℃; for 4h; | 70% |
With potassium hydroxide In water at 40℃; for 16h; Pfitzinger Quinoline Synthesis; | 65% |
Conditions | Yield |
---|---|
With triethylamine In 1,4-dioxane at 20℃; | 98% |
With piperdinium acetate In water at 100℃; Knoevenagel Condensation; | 90% |
Conditions | Yield |
---|---|
for 0.0333333h; microwave irradiation; | 98% |
5-fluoro-1H-indole-2,3-dione
4R-4-hydroxyproline
5-fluoro-3-(1H-pyrrol-1-yl)-1,3-dihydroindol-2-one
Conditions | Yield |
---|---|
With cetyltrimethylammonim bromide In water at 80℃; for 0.5h; Green chemistry; | 98% |
With 1-butyl-3-methylimidazolium Tetrafluoroborate at 110℃; for 0.166667h; Microwave irradiation; | 96% |
With scandium tris(dodecyl sulfate) In water at 80℃; for 0.5h; Green chemistry; | 96% |
With β‐cyclodextrin In water at 60℃; for 1.5h; | 94% |
With iodine In water; acetonitrile at 20℃; for 4h; Irradiation; |
5-fluoro-1H-indole-2,3-dione
dimedone
malononitrile
2-amino-5'-fluoro-7,7-dimethyl-2',5-dioxo-5,6,7,8-tetrahydrospiro[chromene-4,3'-indoline]-3-carbonitrile
Conditions | Yield |
---|---|
With silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride In ethanol at 20℃; for 3.5h; | 98% |
With 1,1'-(butane-1,4-diyl)bis(1,4-diazabicyclo[2.2.2]octan-1-ium) hydroxide In water at 80℃; for 0.166667h; Green chemistry; | 96% |
In water at 80℃; for 0.133333h; Microwave irradiation; Green chemistry; | 95% |
1H-indene-1,3(2H)-dione
5-fluoro-1H-indole-2,3-dione
N,N-dimethyl-aniline
2-(3-(4-(dimethylamino)phenyl)-5-fluoro-2-oxoindolin-3-yl)-1H-indene-1,3(2H)-dione
Conditions | Yield |
---|---|
With lithium perchlorate In ethanol for 4h; Friedel-Crafts type reaction; Reflux; | 98% |
4-hydroxy[1]benzopyran-2-one
5-fluoro-1H-indole-2,3-dione
malononitrile
2'-amino-5-fluoro-2,5'-dioxo-5'H-spiro[indoline-3,4'-pyrano[2,3-b]chromene]-3'-carbonitrile
Conditions | Yield |
---|---|
With silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride In ethanol at 20℃; for 4.5h; | 98% |
With tetrabutylammonium acetate In melt at 100℃; | 93% |
5-fluoro-1H-indole-2,3-dione
3-acetylcoumarin
(R)-5-fluoro-3-hydroxy-3-[2-oxo-2-(2-oxo-2H-chromen-3-yl)ethyl]indolin-2-one
Conditions | Yield |
---|---|
Stage #1: 3-acetylcoumarin With 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R)-(6-methoxyquinolin-4-yl)(3-vinylquinuclidin-7-yl)methyl)urea In tetrahydrofuran at 5℃; for 0.333333h; Aldol Addition; Stage #2: 5-fluoro-1H-indole-2,3-dione In tetrahydrofuran at 5℃; for 24h; Aldol Addition; enantioselective reaction; | 98% |
5-fluoro-1H-indole-2,3-dione
Conditions | Yield |
---|---|
In chloroform at 61℃; for 15h; Inert atmosphere; | 98% |
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