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Kono Chem Co.,Ltd

Xi'an Kono Chem Co., Ltd., founded in 2014, is a holding enterprise of Hongkong Pioneer Biotech Group. It is an export-oriented manufacturing enterprise supported by the Ministry of Commerce. Kono Chem is located in Xi'an, Shaanxi Provin

Genistein

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $800.0 / 1000.0

Type:Other

inquiry

Cartoon Ingredients Co., Ltd

Cartoon Ingredients Co.,Ltd.is located in NanJing, the capital of Jiangsu Province.with Convenient traffic As a manufacturer, the company mainly engaged in providing Food ingredients, Herbal extracts, Vitamins, APIs and Fine chemicals &a

Genistein

Cas:446-72-0

Min.Order:0

Negotiable

Type:Trading Company

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Greenutra Resource Inc

Genistein Product name: Genistein Specification: 98% Appearance: White powder Part Used: Flower Extract Solution: Grain alcohol CAS No: 446-72-0 Introduction Genista is a genus of flowering plants in the legume family Fabac

98% Genistein CAS:446-72-0

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 100.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Genistein Manufacturer/High quality/Best price/In stock

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Pale yellow fine powder Complies Odor Odorless

High quality Genistein with best price cas:446-72-0

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $250.0 / 350.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Genistein supplier in China

Cas:446-72-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

Genistein

Cas:446-72-0

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Best service,high quality and cheap price. Appearance: White Powder Storage:Store in cool & dry place ,do not freeze.keep away from strong light and heat Package:25kg/drum,1kg/bag Application:Mainly used in medicine, health food, tobacco, cosmetics

Genistein

Cas:446-72-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Xi'an Quanao Biotech Co., Ltd.

Come From Nature / Building Healthy Life Beauty In Your Face / Nourishment Your Taste Bud. Professional Factory: We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of con

Natural Thermopsis lanceolate Extract 98% Genistein Powder Cas:446-72-0

Cas:446-72-0

Min.Order:100 Gram

FOB Price: $0.54 / 0.66

Type:Manufacturers

inquiry

Hefei TNJ chemical industry co.,ltd

Functions 1.Be used as antioxidant . 2.Inhibition of angiogenesis, and tyrosine kinases, 3.Antioxidant and anti-estrogen action . 4.Genistein powder is also used to ease menopause symptoms, such as hot flushes. Certifications H

GMP factory supply high quality Genistein

Cas:446-72-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Think Chemical Co. Ltd

Product name Genistein CAS NO. 446-72-0 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on t

Genistein in China

Cas:446-72-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Genistein

Cas:446-72-0

Min.Order:1

Negotiable

Type:Other

inquiry

shanghai Tauto Biotech Co., Ltd

More than 20 years experience in Phytochemical Each product has passed very strict tests (NMR; MS; HPLC) Agents in 13 countries Certified by ISO 9001:2015 quality management system Leader Supplier of Botanical Reference Materials in China M

Genistein

Cas:446-72-0

Min.Order:10 Milligram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Genistein 446-72-0 ISO Producer

Cas:446-72-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

Genistein CAS: 446-72-0 Molecular Formula: C15H10O5 Home Product Category Biomedicine Chinese herbal extracts 446-72-0 446-72-0 - Names and Identifiers Name Genistein Synonyms prunetol Genistein C.I. 75610

Top Quality Natural Genistein 98%

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $35.0 / 49.0

Type:Lab/Research institutions

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Genistein

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Genistein

Cas:446-72-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Shanxi Zorui Biotechnology Co.Ltd.

Zorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ

Natural Gorse Genista Root Extract/ Genistein Powder 99% CAS 446-72-0

Cas:446-72-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Genistein (C.I. 75610)

Cas:446-72-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Genistein CAS NO:446-72-0 Grade:Medical scientific research and export Molecular formula:C15H10O5 Molecular weight:270.2369 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data sto

Genistein/ CAS:446-72-0/raw material/ high-quality

Cas:446-72-0

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scient

TIANFU-CHEM Genistein

Cas:446-72-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Genistein CAS 446-72-0

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $48.0 / 58.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 446-72-0 with fast shipping

Cas:446-72-0

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Lower price USP 99% Genistein CAS:446-72-0 Light yellow powder for sale, manufacturer of China

Cas:446-72-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Genistein/ LIDE PHARMA- Factory supply / Best price

Cas:446-72-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Genistein CAS446-72-0

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $289.0 / 499.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: Genistein Appearance: Light Yellow Powder Cas. No.: 446-72-0 EINECS No.: 207-174-9 Molecular Formula: C15H10O5 Molecular Weight: 270.24 Specification: 99% Appearance:Yellow Crystalline Solid Storage:Store in cool and dry place,

Genistein CAS: 446-72-0

Cas:446-72-0

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

High Quality Natural Gorse/Genista Root Extract Powder Genistein 99% CAS 446-72-0

Cas:446-72-0

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less ten years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermedi

High purity Genistein 99%

Cas:446-72-0

Min.Order:100 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Synthetic route

genistin
529-59-9

genistin

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
β-glucosidase, derived from Aspergillus niger In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;100%
In hydrogenchloride99%
β-glucosidase, derived from almond In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;11.8%
genistein-7-O-β-D-(6''-O-acetylglucopyranoside)
73566-30-0

genistein-7-O-β-D-(6''-O-acetylglucopyranoside)

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
diglycosidase, produced by Penicillium multicolor IAM7153 In methanol at 55℃; for 3h; pH=4; Enzyme kinetics; Aqueous acetate buffer;99.9%
diglycosidase, produced by Aspergillus fumigatus IAM2046 In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;35.2%
β-glucosidase, derived from Aspergillus niger In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;6.2%
β-xylosidase, derived from pectinase G In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;0.5%
sulfur trioxide N,N-dimethylformamide complex

sulfur trioxide N,N-dimethylformamide complex

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin With sodium carbonate In N,N-dimethyl-formamide at 25℃; for 3h;
Stage #2: sulfur trioxide N,N-dimethylformamide complex In N,N-dimethyl-formamide at 0 - 80℃; for 18.5h;
Stage #3: With sulfuric acid; water In N,N-dimethyl-formamide for 0.666667h; Product distribution / selectivity;
95%
2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

sodium formate
141-53-7

sodium formate

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin; sodium formate With propionyl chloride In acetone at 21 - 32℃; for 1h;
Stage #2: With triethylamine In acetone at 20 - 32℃; for 2.5h;
Stage #3: With sulfuric acid; water In acetone at 20℃; for 16h; Product distribution / selectivity;
94.8%
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin; sodium formate With acetyl chloride In acetone at 12 - 25℃; for 2h;
Stage #2: With triethylamine In acetone at 18 - 32℃; for 3h;
Stage #3: With sulfuric acid; water In acetone at 20℃; for 16h; Product distribution / selectivity;
91.7%
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin; sodium formate With isobutyryl chloride In acetone at 21 - 32℃; for 2h;
Stage #2: With triethylamine In acetone at 18 - 32℃; for 2.5h;
Stage #3: With sulfuric acid; water In acetone at 20℃; for 16h; Product distribution / selectivity;
90.2%
2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

sodium formate
141-53-7

sodium formate

propionyl chloride
79-03-8

propionyl chloride

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: sodium formate; propionyl chloride In acetone at 21 - 35℃; for 3h;
Stage #2: 2,4,4',6-tetrahydroxydeoxybenzoin With triethylamine In acetone at 20 - 22℃; for 2h;
Stage #3: With sulfuric acid; water In acetone at 20℃; for 16h;
93%
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin; sodium formate; propionyl chloride In acetone at 21 - 35℃; for 2h;
Stage #2: With triethylamine In acetone at 18 - 35℃; for 3h;
Stage #3: With sulfuric acid; water In acetone at 60 - 70℃; for 1.5h;
92.2%
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin; sodium formate; propionyl chloride In formic acid ethyl ester at 23 - 35℃; for 3h;
Stage #2: With triethylamine In formic acid ethyl ester at 18 - 22℃; for 16h;
Stage #3: With sulfuric acid; water In formic acid ethyl ester at 80℃;
92.7%
3-(4-hydroxyphenyl)-5,7-bis(methoxymethoxy)-4H-1-benzopyran-4-one
1236208-91-5

3-(4-hydroxyphenyl)-5,7-bis(methoxymethoxy)-4H-1-benzopyran-4-one

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With hydrogenchloride; water In methanol; chloroform for 1h; Reflux;92%
2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

sodium formate
141-53-7

sodium formate

isobutyryl chloride
79-30-1

isobutyryl chloride

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin; sodium formate; isobutyryl chloride In acetone at 21 - 32℃; for 3h;
Stage #2: With triethylamine In acetone at 18 - 32℃; for 2h;
Stage #3: With sulfuric acid; water In acetone at 60 - 70℃; for 3h;
90.3%
2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With boron trifluoride diethyl etherate; methanesulfonyl chloride In N,N-dimethyl-formamide at 50℃; for 12h; Molecular sieve;90%
With methanesulfonyl chloride In N,N-dimethyl-formamide at 60 - 70℃; for 1h;53%
Multi-step reaction with 2 steps
1: pyridine / Behandeln des Reaktionsprodukts mit wss. Natronlauge
2: 325 °C
View Scheme
2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: N,N-dimethyl-formamide With phosphorus pentachloride at 55℃; for 0.333333h; Chlorination;
Stage #2: 2,4,4',6-tetrahydroxydeoxybenzoin With boron trifluoride diethyl etherate In N,N-dimethyl-formamide at 20℃; for 1h; Cycloaddition;
90%
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin With boron trifluoride diethyl etherate In N,N-dimethyl-formamide at 50 - 60℃; Cooling with ice;
Stage #2: N,N-dimethyl-formamide With methanesulfonyl chloride at 50 - 70℃;
84%
With boron trifluoride diethyl etherate; methanesulfonyl chloride 1.) irradiation, reflux, 15 s, 2.) irradiation, reflux, 1 min; Yield given. Multistep reaction;
With phosphorus pentachloride; boron trifluoride diethyl etherate at 20℃; for 1h; Cyclization;
With boron trifluoride diethyl etherate; methanesulfonyl chloride at 50 - 100℃;
[5-hydroxy-3-(4-hydroxyphenyl)-4-oxochromen-7-yl]dihydrogen phosphate

[5-hydroxy-3-(4-hydroxyphenyl)-4-oxochromen-7-yl]dihydrogen phosphate

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With sulfatase VIII In water at 37℃; for 0.5h; pH=5.2;89%
formic acid
64-18-6

formic acid

2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

propionic acid anhydride
123-62-6

propionic acid anhydride

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: formic acid; propionic acid anhydride at 25 - 45℃; for 2h;
Stage #2: 2,4,4',6-tetrahydroxydeoxybenzoin With triethylamine In acetone at 20 - 40℃; for 19h;
Stage #3: With sulfuric acid; water In acetone at 60℃;
86.5%
Stage #1: formic acid; 2,4,4',6-tetrahydroxydeoxybenzoin; propionic acid anhydride at 25 - 45℃; for 2h;
Stage #2: With triethylamine at 20 - 40℃; for 19h;
Stage #3: With sulfuric acid; water at 75℃; for 2.5h;
82.5%
5,7-Dihydroxy-3-(4-methoxy-phenyl)-chromen-4-on
491-80-5

5,7-Dihydroxy-3-(4-methoxy-phenyl)-chromen-4-on

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With aluminum (III) chloride In toluene at 140℃; for 6h;84%
With aluminium trichloride In benzene for 18h; Heating;47%
With hydrogen iodide
2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

Propionic formic anhydride
10500-31-9

Propionic formic anhydride

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: 2,4,4',6-tetrahydroxydeoxybenzoin; Propionic formic anhydride With triethylamine In acetone at 25 - 40℃; for 3h;
Stage #2: With sulfuric acid; water In acetone at 20 - 60℃;
84%
6''-O-malonylgenistin
51011-05-3

6''-O-malonylgenistin

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
diglycosidase, produced by Penicillium multicolor IAM7153 In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;82.3%
β-glucosidase, derived from Aspergillus niger In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;12.1%
diglycosidase, produced by Aspergillus fumigatus IAM2046 In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;8.2%
β-xylosidase, derived from pectinase G In methanol at 55℃; for 6h; pH=4; Enzyme kinetics; Aqueous acetate buffer;2%
With Dalbergia nigrescens β-glucosidase In acetate buffer; dimethyl sulfoxide at 37℃; for 0.166667h; pH=5.5; Enzyme kinetics; Further Variations:; Reagents;
formic acid
64-18-6

formic acid

2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: formic acid; 2,4,4',6-tetrahydroxydeoxybenzoin With acetic anhydride; triethylamine at 20℃; for 24h; Industrial scale;
Stage #2: With hydrogenchloride; water In methanol at 20℃; for 22h; Industrial scale;
79.5%
1,3,5-Triazine
290-87-9

1,3,5-Triazine

2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With boron trifluoride diethyl etherate; acetic anhydride In diethyl ether; acetic acid Heating;78%
2-bromo-1-(4'-hydroxyphenyl)-1-ethanone
2491-38-5

2-bromo-1-(4'-hydroxyphenyl)-1-ethanone

2,4,6-trihydroxybenzaldehyde
487-70-7

2,4,6-trihydroxybenzaldehyde

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: 2-bromo-1-(4'-hydroxyphenyl)-1-ethanone With thiamine hydrochloride In ethanol at 20℃; for 0.25h; Green chemistry;
Stage #2: 2,4,6-trihydroxybenzaldehyde In ethanol at 20℃; for 1.58333h; Green chemistry;
75%
2,4,4',6-tetrahydroxydeoxybenzoin
15485-65-1

2,4,4',6-tetrahydroxydeoxybenzoin

sodium formate
141-53-7

sodium formate

benzoyl chloride
98-88-4

benzoyl chloride

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
Stage #1: sodium formate; benzoyl chloride In acetone at 21 - 40℃; for 3h;
Stage #2: 2,4,4',6-tetrahydroxydeoxybenzoin With triethylamine In acetone at 21 - 35℃; for 3h;
Stage #3: With sulfuric acid; water In acetone at 20℃; for 16h;
52.7%
5,7-dihydroxy-3-(4-hydroxy-phenyl)-4-oxo-4H-chromene-2-carboxylic acid
22151-32-2

5,7-dihydroxy-3-(4-hydroxy-phenyl)-4-oxo-4H-chromene-2-carboxylic acid

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
at 325℃;
7-((2S,3R,4R)-3,4-Dihydroxy-4-hydroxymethyl-tetrahydro-furan-2-yloxy)-3-[4-((2R,3S,4S)-3,4-dihydroxy-4-hydroxymethyl-tetrahydro-furan-2-yloxy)-phenyl]-5-hydroxy-chromen-4-one
78694-77-6

7-((2S,3R,4R)-3,4-Dihydroxy-4-hydroxymethyl-tetrahydro-furan-2-yloxy)-3-[4-((2R,3S,4S)-3,4-dihydroxy-4-hydroxymethyl-tetrahydro-furan-2-yloxy)-phenyl]-5-hydroxy-chromen-4-one

B

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With sulfuric acid Heating;
5-O-β-D-glucopyranosylgenistein
128508-06-5

5-O-β-D-glucopyranosylgenistein

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With malic acid at 60℃; other object of study: half-lives; other reagent : acetic acid, oxalic acid, HCl; other temperature;
4′,7-dihydroxy-8β-D-glucose isoflavone
66026-80-0

4′,7-dihydroxy-8β-D-glucose isoflavone

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With hydrogen iodide; phenol at 135℃; for 7h; Heating;25 mg
6,8-di-C-β-D-glucopyranosyl-4',5,7-trihydroxyisoflavone
32361-88-9

6,8-di-C-β-D-glucopyranosyl-4',5,7-trihydroxyisoflavone

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With hydrogen iodide; phenol Heating;20 mg
1-(2-acetoxy-4,6-dihydroxyphenyl)-3,3-dimethoxy-2-(4-hydroxyphenyl)propan-1-one
148356-61-0

1-(2-acetoxy-4,6-dihydroxyphenyl)-3,3-dimethoxy-2-(4-hydroxyphenyl)propan-1-one

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With hydrogenchloride In methanol for 2h; Heating; Yield given;
genistein 7-O-(2"-p-coumaroyl-β-D-glucopyranoside)

genistein 7-O-(2"-p-coumaroyl-β-D-glucopyranoside)

A

D-Glucose
2280-44-6

D-Glucose

B

p-Coumaric Acid
7400-08-0

p-Coumaric Acid

C

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With hydrogenchloride In methanol Heating;
sophoricoside
152-95-4

sophoricoside

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With water Hydrolysis; Acid hydrolysis;
5.7.4'-trimethoxy-isoflavone

5.7.4'-trimethoxy-isoflavone

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With hydrogen iodide; acetic anhydride; acetic acid
genisteine-7-methyl ether

genisteine-7-methyl ether

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Conditions
ConditionsYield
With hydrogen iodide at 130℃;
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

benzenesulfonyl chloride
98-09-9

benzenesulfonyl chloride

3-(4-benzenesulfonyloxyphenyl)-5,7-bis(benzenesulfonyloxy)-4H-chromen-4-one
1041727-57-4

3-(4-benzenesulfonyloxyphenyl)-5,7-bis(benzenesulfonyloxy)-4H-chromen-4-one

Conditions
ConditionsYield
With pyridine at -20℃; for 3h; Inert atmosphere;99%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

acryloyl chloride
814-68-6

acryloyl chloride

C21H14O7

C21H14O7

Conditions
ConditionsYield
With triethylamine In acetone at 20℃; for 24h;98.6%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

acetic anhydride
108-24-7

acetic anhydride

4',5,7-Triacetoxyisoflavone
5995-97-1

4',5,7-Triacetoxyisoflavone

Conditions
ConditionsYield
With pyridine Reflux;98%
With pyridine at 70℃; for 6h;96%
With pyridine In chloroform at 20℃; for 8h; Inert atmosphere;93%
for 6h; Heating;53%
Acetylation;
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Stearoyl chloride
112-76-5

Stearoyl chloride

genistein-4',7-distearate

genistein-4',7-distearate

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 30℃; for 2.5h; Etherification;96%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

7,5,4’-trihydroxy-3’-nitroisoflavone

7,5,4’-trihydroxy-3’-nitroisoflavone

Conditions
ConditionsYield
With ammonium nitrate; trifluoroacetic anhydride In acetonitrile at 20℃; for 1.5h;96%
(Z)-9-octadecenoyl chloride
112-77-6

(Z)-9-octadecenoyl chloride

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

genistein-4',7-dioleate

genistein-4',7-dioleate

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 30℃; for 2.5h; Etherification;95%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

methyl iodide
74-88-4

methyl iodide

4',5,7-trimethoxyisoflavone
1162-82-9

4',5,7-trimethoxyisoflavone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 4h;95%
With potassium carbonate In acetone at 60℃;95%
With potassium carbonate In acetone at 50℃; for 3h; sonication;85%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

1-deoxy-1-fluoro-α-D-glucose
2106-10-7

1-deoxy-1-fluoro-α-D-glucose

genistein 7-α-O-glucoside

genistein 7-α-O-glucoside

Conditions
ConditionsYield
With α-glucosidase from sulfolobus solfataricus In dimethyl sulfoxide at 45℃; for 2h; pH=9; Enzymatic reaction;95%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

acetic anhydride
108-24-7

acetic anhydride

4-(7-acetoxy-5-hydroxy-4-oxo-4H-chromen-3-yl)phenyl acetate
65388-04-7

4-(7-acetoxy-5-hydroxy-4-oxo-4H-chromen-3-yl)phenyl acetate

Conditions
ConditionsYield
In pyridine at 20℃; for 24h;92%
In pyridine at 20℃; for 24h;92%
With pyridine at 20℃; for 24h;92%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

Hexanoyl chloride
142-61-0

Hexanoyl chloride

5,7,4'-tri-O-hexanoyl-genistein
918158-57-3

5,7,4'-tri-O-hexanoyl-genistein

Conditions
ConditionsYield
With pyridine; dmap91%
With pyridine; dmap In chloroform at 20℃; for 9h; Inert atmosphere;91%
With dmap; triethylamine In N,N-dimethyl-formamide at 20℃; for 4.5h; Cooling with ice;81%
With pyridine at 0 - 20℃; for 18h;
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

A

dihydrogenistein
21554-71-2

dihydrogenistein

(3S,4R)-3-(4-Hydroxy-phenyl)-chroman-4,5,7-triol
124093-22-7

(3S,4R)-3-(4-Hydroxy-phenyl)-chroman-4,5,7-triol

Conditions
ConditionsYield
With ammonium formate; palladium on activated charcoal In methanol Ambient temperature;A 90%
B n/a
With ammonium formate; palladium on activated charcoal In methanol for 2h; Heating;A 59%
B 21%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

4',5,7-tri(3-bromopropoxy)isoflavone
862255-04-7

4',5,7-tri(3-bromopropoxy)isoflavone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 1.5h; sonication;90%
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 4.75h;
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

benzenesulfonyl chloride
98-09-9

benzenesulfonyl chloride

3-(4-hydroxyphenyl)-7-benzenesulfonyloxy-5-hydroxy-4H-chromen-4-one
1041727-51-8

3-(4-hydroxyphenyl)-7-benzenesulfonyloxy-5-hydroxy-4H-chromen-4-one

Conditions
ConditionsYield
With pyridine In tetrahydrofuran at -20℃; for 0.333333h; Inert atmosphere;90%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

tetra(n-butyl)ammonium hydroxide
2052-49-5

tetra(n-butyl)ammonium hydroxide

tetra n-butylammonium salt of genistein

tetra n-butylammonium salt of genistein

Conditions
ConditionsYield
In methanol; water at 20℃;89%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

ethylene dibromide
106-93-4

ethylene dibromide

7-(2-bromoethoxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
862255-00-3

7-(2-bromoethoxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide sonication;88%
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 1.5h; sonication;86%
With sodium hydrogencarbonate In acetone at 65℃; for 24h;71%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

acetic anhydride
108-24-7

acetic anhydride

A

4-(7-acetoxy-5-hydroxy-4-oxo-4H-chromen-3-yl)phenyl acetate
65388-04-7

4-(7-acetoxy-5-hydroxy-4-oxo-4H-chromen-3-yl)phenyl acetate

B

7-acetoxy-4',5-dihydroxygenistein

7-acetoxy-4',5-dihydroxygenistein

Conditions
ConditionsYield
With pyridine for 7h; Reflux;A 87.2%
B 5.3%
(Z)-9-octadecenoyl chloride
112-77-6

(Z)-9-octadecenoyl chloride

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

genistein-7-monooleate

genistein-7-monooleate

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 30℃; for 2.5h; Etherification;87%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

7-(3-bromopropoxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
862255-02-5

7-(3-bromopropoxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide sonication;87%
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 1.5h; sonication;85%
With sodium hydrogencarbonate; potassium carbonate In acetone at 65℃; for 8h;78.47%
5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on
446-72-0

5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on

chloromethyl methyl ether
107-30-2

chloromethyl methyl ether

5,7,4'-trimethoxymethoxyisoflavone

5,7,4'-trimethoxymethoxyisoflavone

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 2h;87%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 2h;87%
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