Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:111974-72-2
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryItems Standard Result Assay 98%min -----------------------------------------------------------------------------------------------
Cas:111974-72-2
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Trading Company
inquiryUnique advantages for Quetiapine fumarate Cas 111974-72-2 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White Powder Storage:-20°C Freezer Package:1kg/foil bag, 25
Cas:111974-72-2
Min.Order:1 Kilogram
FOB Price: $140.0
Type:Trading Company
inquiry1. Quality Our products meet MSDS safe standard and we have ISO and other certificate so yan can get high quality products from our company. 2. Price We are the company which is the joint of trade and industry so we cao provide the competiti
Cas:111974-72-2
Min.Order:25 Kilogram
Negotiable
Type:Trading Company
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:111974-72-2
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:111974-72-2
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryTIANFUCHEM-- 111974-72-2 -- Quetiapine fumarate in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business re
Cas:111974-72-2
Min.Order:1 Metric Ton
FOB Price: $2000.0
Type:Lab/Research institutions
inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be
Cas:111974-72-2
Min.Order:1 Gram
FOB Price: $1.0 / 2.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:111974-72-2
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:111974-72-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryName: Quetiapine fumarate CAS: 111974-72-2 Molecular Formula:C46H54N6O8S2 Property: white powder Assay: 99% Appearance:White powder Storage:RT. Package:drum Application
Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car
Appearance:White or off- white crystalline powder Storage:R.T Package:25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in China
Cas:111974-72-2
Min.Order:1 Kilogram
FOB Price: $150.0 / 200.0
Type:Lab/Research institutions
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:off-white to brownish crystalline powder Storage:Store in se
Cas:111974-72-2
Min.Order:100 Gram
Negotiable
Type:Other
inquiryHanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
Cas:111974-72-2
Min.Order:1 Kilogram
FOB Price: $200.0 / 400.0
Type:Trading Company
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:111974-72-2
Min.Order:10 Gram
FOB Price: $3.5
Type:Trading Company
inquiryProduct Name: Quetiapine fumarate CAS: 111974-72-2 MF: C46H54N6O8S2 MW: 883.09 EINECS: 1308068-626-2 Mol File: 111974-72-2.mol Quetiapine fumarate Structure Quetiapine fumarate Chemical Properties Melting point 174-176°C F
Cas:111974-72-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:111974-72-2
Min.Order:1 Kilogram
FOB Price: $172.0 / 189.0
Type:Trading Company
inquiryQuetiapine fumarate CAS:111974-72-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte
Cas:111974-72-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:111974-72-2
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryProduct Detail Minimum Order Qty. 10 Gram
Cas:111974-72-2
Min.Order:10 Gram
Negotiable
Type:Trading Company
inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:111974-72-2
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiryQuetiapine fumarate CAS: 111974-72-2 Specification items of test as per company standard ws1-(x-133)-2003z & zlbz-e023-3 result characters appearance: white or pale yellow
Cas:111974-72-2
Min.Order:1 Kilogram
Negotiable
Type:Other
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
We have overseas warehouses in California, Nuevo Laredo, Mexico, Vancouver, Canada, Amsterdam, The Netherlands and Melbourne, Australia. Overseas warehouses can provide some of the best selling products. We look forward to cooperating with strong loc
Cas:111974-72-2
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:111974-72-2
Min.Order:1 Kilogram
FOB Price: $1.0 / 100000.0
Type:Lab/Research institutions
inquiryEUGMP/FDA 98.5%min Appearance:Off-white or yellowish-white crystalline powder Storage:Room temperature Package:as required Application:used in medicine Transportation:by sea by air express Port:China main port
Cas:111974-72-2
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryOur company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-
Cas:111974-72-2
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
In ethyl acetate; toluene at 20℃; for 1.08333h; Product distribution / selectivity; Heating / reflux; | 99% |
Stage #1: Quetiapine With pyrographite In methanol for 0.5h; Reflux; Stage #2: (2E)-but-2-enedioic acid at 40℃; pH=4 - 5; | 98% |
In methanol at 10 - 25℃; for 1.58333h; Heating / reflux; | 94% |
1-[2-(2-hydroxyethoxy)ethyl]piperazine
dibenzo[b,f][1,4]thiazepin-11-ylamine hydrochloride
(2E)-but-2-enedioic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Stage #1: 1-[2-(2-hydroxyethoxy)ethyl]piperazine; dibenzo[b,f][1,4]thiazepin-11-ylamine hydrochloride at 172 - 176℃; for 5h; Stage #2: In water at 20 - 65℃; Stage #3: (2E)-but-2-enedioic acid In isopropyl alcohol at 4 - 20℃; Product distribution / selectivity; | 83% |
Stage #1: 1-[2-(2-hydroxyethoxy)ethyl]piperazine; dibenzo[b,f][1,4]thiazepin-11-ylamine hydrochloride at 173 - 175℃; for 5h; Stage #2: With potassium carbonate In water at 20 - 75℃; Stage #3: (2E)-but-2-enedioic acid In isopropyl alcohol at 4 - 20℃; Product distribution / selectivity; | 79% |
titanium(IV) isopropylate
1-[2-(2-hydroxyethoxy)ethyl]piperazine
dibenzo[b,f][1,4]thiazepin-11-one
A
isopropyl alcohol
B
quetiapine fumarate
Conditions | Yield |
---|---|
With pentan-1-ol at 160℃; for 32h; Product distribution / selectivity; Heating / reflux; | A n/a B 75% |
11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride
2-(2-Chloroethoxy)ethanol
quetiapine fumarate
Conditions | Yield |
---|---|
Stage #1: 11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride; 2-(2-Chloroethoxy)ethanol With sodium carbonate; sodium iodide; tetrabutylammomium bromide In toluene at 105℃; for 24h; Heating / reflux; Stage #2: With (2E)-but-2-enedioic acid In toluene Heating / reflux; | 72% |
Stage #1: 11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride; 2-(2-Chloroethoxy)ethanol With sodium carbonate; sodium iodide; tetrabutylammomium bromide In toluene at 107℃; for 40h; Heating / reflux; Stage #2: With (2E)-but-2-enedioic acid In toluene at 100℃; | 72% |
Stage #1: 11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride; 2-(2-Chloroethoxy)ethanol With sodium carbonate; sodium iodide; tetrabutylammomium bromide In butan-1-ol at 115 - 120℃; for 24h; Heating / reflux; Stage #2: With (2E)-but-2-enedioic acid In butan-1-ol Heating / reflux; | 70.8% |
(2E)-but-2-enedioic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Stage #1: 11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)dibenzo[b,f]-1,4-thiazepine hydrochloride With sodium hydroxide In methanol; water; toluene at 40 - 50℃; for 0.166667h; pH=13 - 14; Stage #2: (2E)-but-2-enedioic acid In ethanol for 0.166667h; Heating / reflux; |
1-[2-(2-hydroxyethoxy)ethyl]piperazine
11-chloro-dibenzo[b,f][1,4]thiazepine
(2E)-but-2-enedioic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Stage #1: 1-[2-(2-hydroxyethoxy)ethyl]piperazine; 11-chloro-dibenzo[b,f][1,4]thiazepine In toluene at 25 - 112℃; Large scale reaction; Stage #2: (2E)-but-2-enedioic acid In ethanol at 55 - 60℃; for 0.5h; Large scale reaction; | 15.4 kg |
11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride
2-(2-Chloroethoxy)ethanol
(2E)-but-2-enedioic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Stage #1: 11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride; 2-(2-Chloroethoxy)ethanol With 1-methyl-pyrrolidin-2-one; sodium carbonate; sodium iodide In propan-1-ol Stage #2: (2E)-but-2-enedioic acid In ethanol |
2-(2-Chloroethoxy)ethanol
(2E)-but-2-enedioic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Stage #1: With sodium hydrogencarbonate In water; dimethyl sulfoxide at 20℃; for 0.166667h; Stage #2: 2-(2-Chloroethoxy)ethanol; sodium iodide In water; dimethyl sulfoxide; toluene at 95 - 100℃; Stage #3: (2E)-but-2-enedioic acid In ethanol at 45 - 80℃; |
dibenzo[b,f][1,4]thiazepin-11-one
quetiapine fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: trichlorophosphate; N,N-dimethyl-aniline / 6 h / 20 - 100 °C / Industry scale; Inert atmosphere 2.1: toluene; dimethyl sulfoxide / 3 h / 25 - 30 °C / Industry scale; Inert atmosphere 3.1: sodium hydrogencarbonate / water; dimethyl sulfoxide / 0.17 h / 20 °C / Industry scale 3.2: 95 - 100 °C / Industry scale 3.3: 4 h / 5 - 80 °C / Industry scale View Scheme | |
Multi-step reaction with 3 steps 1.1: pyrophosphoryl chloride; N,N-dimethyl-aniline / toluene / 4.5 h / 110 - 112 °C / Green chemistry 2.1: toluene / 105 - 107 °C 3.1: pyrographite / methanol / 0.5 h / Reflux 3.2: 40 °C / pH 4 - 5 View Scheme |
2-(2-Chloroethoxy)ethanol
(2E)-but-2-enedioic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Stage #1: N-Dealkyl Quetiapine dihydrochloride With sodium hydrogencarbonate In water; dimethyl sulfoxide at 20℃; for 0.166667h; Industry scale; Stage #2: 2-(2-Chloroethoxy)ethanol With sodium iodide In water; dimethyl sulfoxide; toluene at 95 - 100℃; Industry scale; Stage #3: (2E)-but-2-enedioic acid In ethanol at 5 - 80℃; for 4h; Product distribution / selectivity; Industry scale; |
2‑(2‑nitrophenylsulfanyl)benzoic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: thionyl chloride / dichloromethane / 40 °C 1.2: 0 - 5 °C 2.1: formic acid; iron / 85 - 90 °C 3.1: methanol View Scheme |
Thiosalicylic acid
quetiapine fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium hydroxide / water; isopropyl alcohol / Inert atmosphere; Reflux 2.1: thionyl chloride / dichloromethane / 40 °C 2.2: 0 - 5 °C 3.1: formic acid; iron / 85 - 90 °C 4.1: methanol View Scheme |
2-Chloronitrobenzene
quetiapine fumarate
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium hydroxide / water; isopropyl alcohol / Inert atmosphere; Reflux 2.1: thionyl chloride / dichloromethane / 40 °C 2.2: 0 - 5 °C 3.1: formic acid; iron / 85 - 90 °C 4.1: methanol View Scheme |
quetiapine fumarate
11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)dibenzo[b,f]-1,4-thiazepine hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In ethanol at 0 - 60℃; for 7.5h; Product distribution / selectivity; | |
With hydrogenchloride In water; isopropyl alcohol at 0 - 70℃; for 8.5h; Product distribution / selectivity; |
ethyl bromide
quetiapine fumarate
2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-1-ethyl ethanol
Conditions | Yield |
---|---|
With sodium hydroxide In N,N-dimethyl-formamide at 15 - 20℃; for 8h; |
Conditions | Yield |
---|---|
In water |
Conditions | Yield |
---|---|
In water |
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