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Greenutra Resource Inc

Mango Powder Specification: Name: Mango Powder Identification Standardization Aspect brown fine powder

Mango Powder

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $24.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Hangzhou DaAppearance:yellow powder Storage:Store in dry, dark and ventilated place. Package:according to the clients requirement Application:MAO inhibitor Transportation:by air or by sea Port:Shanghai

Mangiferin TOP suppler in China

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Physicochemical Appearance Off-white to yellowish powder Conform

High purity Mangiferin with high quality and best price cas:4773-96-0

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $400.0 / 500.0

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Superiority KONO is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality

Mango extract Mangiferin 98% with best price

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $450.0 / 480.0

Type:Other

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Mangiferin supplier in China

Cas:4773-96-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Xi'an Quanao Biotech Co., Ltd.

QA Factory Supply Manggo Leaf Extract 95% Mangiferin for liver health Xi'an Quanao Biotech Co., Ltd. is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed ad

QA Factory Supply Manggo Leaf Extract 95% Mangiferin for liver health

Cas:4773-96-0

Min.Order:100 Kilogram

FOB Price: $0.48 / 0.56

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Mangiferin

Cas:4773-96-0

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Mango Powder

Cas:4773-96-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Mangiferin

Cas:4773-96-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Mangiferin Alias: Mango glycoside 、 Damuning English Name:Mangiferin CSA:4773-96-0 Molecular formula:C19H18O11 Molecular weight:422.35 Packaging Specification: 25kg/drum high purity 99%min stock Hubei DiBo Chemical Co., Ltd. was foun

Mangiferin/powder /CAS:4773-96-0/Manufacturer provides straightly

Cas:4773-96-0

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Density: 1.843 ± 0.06 g/cm3 (Predicted) Melting point: 269-270 ° C Boiling point: 842.7 ± 65.0 ° C (Predicted) Specific rotation:+43.3 ° (c=0.9, pyridine) Flash point: 303.6 ° C Steam pressure: 3.67E-30mmHg at 25 ° C

Mangiferin 4773-96-0

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Mangiferin 4773-96-0

Cas:4773-96-0

Min.Order:1 Metric Ton

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 4773-96-0 with competitive price

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: Xanthone-c-glucoside Synonyms: mangiferin CAS:4773-96-0 MF: C19H18O11 Appearance: Light yellow power Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Health Food Transportation:By sea or by air

Xanthone-c-glucoside CAS:4773-96-0

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

9H-Xanthen-9-one, 2-b-D-glucopyranosyl-1,3,6,7-tetrahydroxy- 4773-96-0

Cas:4773-96-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

9H-Xanthen-9-one, 2-b-D-glucopyranosyl-1,3,6,7-tetrahydroxy-/ LIDE PHARMA- Factory supply / Best price

Cas:4773-96-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Mangiferin Oxychlorophenone

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $100.0 / 120.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

mangiferin CAS:4773-96-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

mangiferin CAS:4773-96-0

Cas:4773-96-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

9H-Xanthen-9-one, 2-b-D-glucopyranosyl-1,3,6,7-tetrahydroxy-

Cas:4773-96-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 4773-96-0 Mangiferin

Cas:4773-96-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

Mangiferin

Cas:4773-96-0

Min.Order:1 Kilogram

FOB Price: $10.0 / 30.0

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

PRODUCT DETAILS

China Biggest Manufacturer factory sales Mangiferin CAS 4773-96-0

Cas:4773-96-0

Min.Order:100 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

ShangHai Soyoung Biotechnology Inc

Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye

Mango extract 98% Mangiferin

Cas:4773-96-0

Min.Order:25 Kilogram

FOB Price: $310.0

Type:Lab/Research institutions

inquiry

Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered

Mangiferin

Cas:4773-96-0

Min.Order:25 Kilogram

FOB Price: $357.74

Type:Trading Company

inquiry

Chengdu Biopurify Phytochemicals Ltd.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic

Mangiferin

Cas:4773-96-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

Mangiferin

Cas:4773-96-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

9H-XANTHEN-9-ONE

Cas:4773-96-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

mangiferin

Cas:4773-96-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6-methoxy-1,3,7-trihydroxyxanthone
1239694-50-8

2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6-methoxy-1,3,7-trihydroxyxanthone

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
With boron tribromide In dichloromethane at 0 - 20℃;94%
1,6,7-trihydroxy-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-3-O-benzylxanthone

1,6,7-trihydroxy-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-3-O-benzylxanthone

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
With 10% palladium hydroxide on charcoal; hydrogen In methanol at 20℃; under 760.051 Torr; for 48h;90%
3-glucosyl-2,3′,4,4′,6-pentahydroxybenzophenone
92631-83-9

3-glucosyl-2,3′,4,4′,6-pentahydroxybenzophenone

A

4-β-D-glucopyranosyl-1,3-6,7-tetrahydroxy-9H-xanthen-9-one
24699-16-9

4-β-D-glucopyranosyl-1,3-6,7-tetrahydroxy-9H-xanthen-9-one

B

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
With sodium carbonate; potassium hexacyanoferrate(III) In water for 1.5h; Ambient temperature;A 12 mg
B 7 mg
With sodium carbonate; potassium hexacyanoferrate(III) In water for 1.5h; Product distribution; Ambient temperature;A 12 mg
B 7 mg
6′-O-galloyl-mangiferin
92631-82-8

6′-O-galloyl-mangiferin

A

3,4,5-trihydroxybenzoic acid
149-91-7

3,4,5-trihydroxybenzoic acid

B

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
In water at 37℃; tannase;
6′-O-acetyl mangiferin

6′-O-acetyl mangiferin

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
With hydrogenchloride In water at 100℃; for 1h; Product distribution; other reagent (2N NaOH); other temp.;
maclurin 3-C-(6''-O-p-hydroxybenzoyl)-β-D-glucoside
92665-82-2

maclurin 3-C-(6''-O-p-hydroxybenzoyl)-β-D-glucoside

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 20 mg / H2O / 35 °C / hesperidinase
2: 7 mg / K3, Na2CO3 / H2O / 1.5 h / Ambient temperature
View Scheme
maclurin 3-C-(2''-O-p-hydroxybenzoyl-6''-O-galloyl)-β-D-glucoside
92631-85-1

maclurin 3-C-(2''-O-p-hydroxybenzoyl-6''-O-galloyl)-β-D-glucoside

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 40 mg / H2O / 37 °C / hesperidinase
2: 7 mg / K3, Na2CO3 / H2O / 1.5 h / Ambient temperature
View Scheme
maclurin 3-C-(2''-O-galloyl-6''-O-p-hydroxybenzoyl)-β-D-glucoside
92631-84-0

maclurin 3-C-(2''-O-galloyl-6''-O-p-hydroxybenzoyl)-β-D-glucoside

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: H2O / 0.5 h / 37 °C / tannase
2: 20 mg / H2O / 35 °C / hesperidinase
3: 7 mg / K3, Na2CO3 / H2O / 1.5 h / Ambient temperature
View Scheme
C19H18O11*C42H70O35

C19H18O11*C42H70O35

A

mangiferin
4773-96-0

mangiferin

B

β‐cyclodextrin
7585-39-9

β‐cyclodextrin

Conditions
ConditionsYield
In ethanol at 25℃; for 2h; Kinetics; Wavelength;
3-glucosyl-2,3′,4,4′,6-pentahydroxybenzophenone
92631-83-9

3-glucosyl-2,3′,4,4′,6-pentahydroxybenzophenone

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
With ethylenediaminetetraacetic acid; NADPH at 30℃; for 2h; Enzymatic reaction;
maclurin
519-34-6

maclurin

4-nitrophenyl-β-D-glucoside
2492-87-7

4-nitrophenyl-β-D-glucoside

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: UDP; Mangifera indica C-glycosyltransferase / 12 h / Enzymatic reaction
2: NADPH; ethylenediaminetetraacetic acid / 2 h / 30 °C / Enzymatic reaction
View Scheme
UDP-glucose
133-89-1

UDP-glucose

maclurin
519-34-6

maclurin

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Mangifera indica C-glycosyltransferase / 12 h / Enzymatic reaction
2: NADPH; ethylenediaminetetraacetic acid / 2 h / 30 °C / Enzymatic reaction
View Scheme
Conditions
ConditionsYield
Multi-step reaction with 10 steps
1.1: pyridine / 12 h / 20 °C
2.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
3.1: trichlorophosphate / 16 h / 20 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
4.2: 1 h / -40 °C / Inert atmosphere
5.1: manganese(IV) oxide / dichloromethane / 36 h
6.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
7.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
8.1: caesium carbonate / methanol / 12 h / 80 °C
9.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
10.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
β-D-glucose pentaacetate
604-69-3

β-D-glucose pentaacetate

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 14 steps
1.1: boron trifluoride diethyl etherate / dichloromethane / 12 h / 20 °C / Inert atmosphere
2.1: sodium methylate / methanol / 1 h / 20 °C / pH 11 - 12
3.1: sodium hydride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C
4.1: N-Bromosuccinimide; water / acetone / 3 h / 20 °C / Darkness
5.1: pyridine / 12 h / 20 °C
6.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
7.1: trichlorophosphate / 16 h / 20 °C / Inert atmosphere
8.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
8.2: 1 h / -40 °C / Inert atmosphere
9.1: manganese(IV) oxide / dichloromethane / 36 h
10.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
11.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
12.1: caesium carbonate / methanol / 12 h / 80 °C
13.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
14.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
1-O-acetyl-2,3,4,6-tetra-O-benzyl-D-glucopyranose
80300-30-7

1-O-acetyl-2,3,4,6-tetra-O-benzyl-D-glucopyranose

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
2.1: trichlorophosphate / 16 h / 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
3.2: 1 h / -40 °C / Inert atmosphere
4.1: manganese(IV) oxide / dichloromethane / 36 h
5.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
6.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
7.1: caesium carbonate / methanol / 12 h / 80 °C
8.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
9.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
1,2,4-Trihydroxybenzene
533-73-3

1,2,4-Trihydroxybenzene

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12.5 h / 0 - 20 °C
2.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 12 h / 20 °C
3.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
3.2: 1 h / -40 °C / Inert atmosphere
4.1: manganese(IV) oxide / dichloromethane / 36 h
5.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
6.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
7.1: caesium carbonate / methanol / 12 h / 80 °C
8.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
9.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
1,2,4-tris(methoxymethoxy)benzene
156862-15-6

1,2,4-tris(methoxymethoxy)benzene

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 12 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
2.2: 1 h / -40 °C / Inert atmosphere
3.1: manganese(IV) oxide / dichloromethane / 36 h
4.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
5.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
6.1: caesium carbonate / methanol / 12 h / 80 °C
7.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
8.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
1-bromo-2,4,5-tris(methoxymethoxy)benzene

1-bromo-2,4,5-tris(methoxymethoxy)benzene

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
1.2: 1 h / -40 °C / Inert atmosphere
2.1: manganese(IV) oxide / dichloromethane / 36 h
3.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
4.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
5.1: caesium carbonate / methanol / 12 h / 80 °C
6.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
7.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
1,3,5-tri-O-benzyl-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)benzene
115130-39-7

1,3,5-tri-O-benzyl-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)benzene

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: trichlorophosphate / 16 h / 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
2.2: 1 h / -40 °C / Inert atmosphere
3.1: manganese(IV) oxide / dichloromethane / 36 h
4.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
5.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
6.1: caesium carbonate / methanol / 12 h / 80 °C
7.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
8.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
p-tolyl-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside
28244-94-2, 28244-99-7, 86782-41-4, 131488-65-8

p-tolyl-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 13 steps
1.1: sodium methylate / methanol / 1 h / 20 °C / pH 11 - 12
2.1: sodium hydride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C
3.1: N-Bromosuccinimide; water / acetone / 3 h / 20 °C / Darkness
4.1: pyridine / 12 h / 20 °C
5.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
6.1: trichlorophosphate / 16 h / 20 °C / Inert atmosphere
7.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
7.2: 1 h / -40 °C / Inert atmosphere
8.1: manganese(IV) oxide / dichloromethane / 36 h
9.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
10.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
11.1: caesium carbonate / methanol / 12 h / 80 °C
12.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
13.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
2,4,6-tri-O-benzyl-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)benzaldehyde

2,4,6-tri-O-benzyl-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)benzaldehyde

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
1.2: 1 h / -40 °C / Inert atmosphere
2.1: manganese(IV) oxide / dichloromethane / 36 h
3.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
4.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
5.1: caesium carbonate / methanol / 12 h / 80 °C
6.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
7.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
C74H76O15

C74H76O15

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: manganese(IV) oxide / dichloromethane / 36 h
2: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
3: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
4: caesium carbonate / methanol / 12 h / 80 °C
5: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
6: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
2,4,6-tribenzyloxy-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-2′,4′,5′-tris(methoxymethoxy)benzophenone

2,4,6-tribenzyloxy-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-2′,4′,5′-tris(methoxymethoxy)benzophenone

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
2: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
3: caesium carbonate / methanol / 12 h / 80 °C
4: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
5: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
2,4,6-tribenzyloxy-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-2′,4′,5′-trihydroxybenzophenone

2,4,6-tribenzyloxy-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-2′,4′,5′-trihydroxybenzophenone

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
2: caesium carbonate / methanol / 12 h / 80 °C
3: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
4: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
2,4,6-tribenzyloxy-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-2′-hydroxy-4′,5′-bis(methoxymethoxy)benzophenone

2,4,6-tribenzyloxy-3-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-2′-hydroxy-4′,5′-bis(methoxymethoxy)benzophenone

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: caesium carbonate / methanol / 12 h / 80 °C
2: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
3: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
1,3-di-O-benzyl-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6,7-di-O-methoxymethylxanthone

1,3-di-O-benzyl-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6,7-di-O-methoxymethylxanthone

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
2: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
p-methylphenyl 1-thio-β-D-glucopyranoside
1152-39-2

p-methylphenyl 1-thio-β-D-glucopyranoside

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C
2.1: N-Bromosuccinimide; water / acetone / 3 h / 20 °C / Darkness
3.1: pyridine / 12 h / 20 °C
4.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
5.1: trichlorophosphate / 16 h / 20 °C / Inert atmosphere
6.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
6.2: 1 h / -40 °C / Inert atmosphere
7.1: manganese(IV) oxide / dichloromethane / 36 h
8.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
9.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
10.1: caesium carbonate / methanol / 12 h / 80 °C
11.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
12.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
p-methylphenyl 2,3,4,6-tetra-O-benzyl-thio-β-D-glucopyranoside
131531-76-5

p-methylphenyl 2,3,4,6-tetra-O-benzyl-thio-β-D-glucopyranoside

mangiferin
4773-96-0

mangiferin

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1.1: N-Bromosuccinimide; water / acetone / 3 h / 20 °C / Darkness
2.1: pyridine / 12 h / 20 °C
3.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
4.1: trichlorophosphate / 16 h / 20 °C / Inert atmosphere
5.1: n-butyllithium / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
5.2: 1 h / -40 °C / Inert atmosphere
6.1: manganese(IV) oxide / dichloromethane / 36 h
7.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
8.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
9.1: caesium carbonate / methanol / 12 h / 80 °C
10.1: toluene-4-sulfonic acid / methanol / 0.5 h / 80 °C
11.1: 10% palladium hydroxide on charcoal; hydrogen / methanol / 48 h / 20 °C / 760.05 Torr
View Scheme
acetic anhydride
108-24-7

acetic anhydride

mangiferin
4773-96-0

mangiferin

2-β-D-tetraacetoxyglucopyranosyl-1,6,7-triacetoxy-3-hydroxy-9H-xanthen-9-one

2-β-D-tetraacetoxyglucopyranosyl-1,6,7-triacetoxy-3-hydroxy-9H-xanthen-9-one

Conditions
ConditionsYield
With sodium acetate; acetic acid at 120℃; for 3.5h;93.6%
mangiferin
4773-96-0

mangiferin

mangiferin calcium

mangiferin calcium

Conditions
ConditionsYield
With calcium hydroxide In dimethyl sulfoxide; glycerol Product distribution / selectivity;90.4%
With potassium hydrogencarbonate In ethanol; water Product distribution / selectivity;82.1%
mangiferin
4773-96-0

mangiferin

mangiferin-3-monosodium
929635-04-1

mangiferin-3-monosodium

Conditions
ConditionsYield
With sodium carbonate In ethanol; water Product distribution / selectivity;81.7%
mangiferin
4773-96-0

mangiferin

mangiferin-3-monopotassium
1158716-92-7

mangiferin-3-monopotassium

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethanol; water Product distribution / selectivity;78.1%
acetic anhydride
108-24-7

acetic anhydride

mangiferin
4773-96-0

mangiferin

1,3,6,7-tetra-O-acetyl-2-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)xanthone
4706-56-3

1,3,6,7-tetra-O-acetyl-2-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)xanthone

Conditions
ConditionsYield
With iodine at 130℃; for 0.25h; Microwave irradiation;78%
With pyridine at 20℃; for 36h;
mangiferin
4773-96-0

mangiferin

mangiferin-6-O-calcium salt

mangiferin-6-O-calcium salt

Conditions
ConditionsYield
Stage #1: mangiferin With sodium hydrogencarbonate In water; dimethyl sulfoxide at 85℃;
Stage #2: With calcium chloride In water; dimethyl sulfoxide at 20℃; Reagent/catalyst;
74.5%
mangiferin
4773-96-0

mangiferin

mangiferin-6-O-potassium salt

mangiferin-6-O-potassium salt

Conditions
ConditionsYield
With potassium carbonate In water; dimethyl sulfoxide at 60℃; Temperature;60.2%
mangiferin
4773-96-0

mangiferin

mangiferin-6-O-sodium salt

mangiferin-6-O-sodium salt

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; dimethyl sulfoxide at 85℃; Temperature; Reagent/catalyst;50.5%
copper(II) nitrate trihydrate

copper(II) nitrate trihydrate

water
7732-18-5

water

mangiferin
4773-96-0

mangiferin

C19H20CuO13*5H2O

C19H20CuO13*5H2O

Conditions
ConditionsYield
With triethylamine In ethanol at 65℃; for 5h; pH=7.5;46%
mangiferin
4773-96-0

mangiferin

norathyriol
3542-72-1

norathyriol

Conditions
ConditionsYield
With hydrogen iodide; phenol for 7h; Heating;43%
With hydrogenchloride; recorcinol In water for 6h; Reagent/catalyst; Reflux;
With hydrogenchloride; recorcinol In water at 150℃; for 6h; Reagent/catalyst; Green chemistry;
zinc(II) nitrate hexahydrate

zinc(II) nitrate hexahydrate

water
7732-18-5

water

mangiferin
4773-96-0

mangiferin

C19H20O13Zn*4H2O

C19H20O13Zn*4H2O

Conditions
ConditionsYield
With triethylamine In methanol; ethanol at 65℃; for 6h; pH=7.5;40%
cinnamoyl chloride
102-92-1

cinnamoyl chloride

mangiferin
4773-96-0

mangiferin

2-β-D-glucopyranosyl-7-cinnamoyloxy-1,3,6-trihydroxy-9H-xanthen-9-one

2-β-D-glucopyranosyl-7-cinnamoyloxy-1,3,6-trihydroxy-9H-xanthen-9-one

Conditions
ConditionsYield
With pyridine at 20℃; for 20h;
dimethyl sulfate
77-78-1

dimethyl sulfate

mangiferin
4773-96-0

mangiferin

2-β-D-tetrahydroxyglucopyranosyl-3,6,7-trimethoxy-1-hydroxy-9H-xanthen-9-one

2-β-D-tetrahydroxyglucopyranosyl-3,6,7-trimethoxy-1-hydroxy-9H-xanthen-9-one

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 168h;
Cinnamoyl chloride
102-92-1

Cinnamoyl chloride

mangiferin
4773-96-0

mangiferin

2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one

2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one

Conditions
ConditionsYield
With pyridine at 20℃; for 20h;
Cinnamoyl chloride
102-92-1

Cinnamoyl chloride

mangiferin
4773-96-0

mangiferin

2-β-D-tetracinnamoylglucopyranosyl-7-cynnamoyloxy-1,3,6-trihydroxy-9H-xanthen-9-one

2-β-D-tetracinnamoylglucopyranosyl-7-cynnamoyloxy-1,3,6-trihydroxy-9H-xanthen-9-one

Conditions
ConditionsYield
With pyridine at 20℃; for 600h;
mangiferin
4773-96-0

mangiferin

1,3,6,7-tetrahydroxyxanthone acetate
2054-37-7

1,3,6,7-tetrahydroxyxanthone acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 43 percent / phenol, hydroiodic acid (d= 1.7) / 7 h / Heating
2: pyridine / 24 h
View Scheme
potassium carbonate
584-08-7

potassium carbonate

mangiferin
4773-96-0

mangiferin

A

mangiferin-3-monopotassium
1158716-92-7

mangiferin-3-monopotassium

B

mangiferin-7-monopotassium
1158716-92-7

mangiferin-7-monopotassium

Conditions
ConditionsYield
In methanol; water Product distribution / selectivity;
sodium hydrogencarbonate
144-55-8

sodium hydrogencarbonate

mangiferin
4773-96-0

mangiferin

A

mangiferin-3-monosodium
929635-04-1

mangiferin-3-monosodium

B

mangiferin-7-monosodium
929635-04-1

mangiferin-7-monosodium

Conditions
ConditionsYield
In ethanol; water Product distribution / selectivity;
sodium carbonate
497-19-8

sodium carbonate

mangiferin
4773-96-0

mangiferin

A

mangiferin-3-monosodium
929635-04-1

mangiferin-3-monosodium

B

mangiferin-7-monosodium
929635-04-1

mangiferin-7-monosodium

Conditions
ConditionsYield
In ethanol; water Product distribution / selectivity;
calcium hydroxide

calcium hydroxide

mangiferin
4773-96-0

mangiferin

mangiferin calcium

mangiferin calcium

Conditions
ConditionsYield
In dimethyl sulfoxide; glycerol Product distribution / selectivity;

Downstream Products

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