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Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualified

Factory Supply 2,3-Dichloropyrazine Supplier Manufacturer With Competitive Price

Cas:4858-85-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2,3-Dichloropyrazine Manufacturer/High quality/Best price/In stock

Cas:4858-85-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

Xi'an Kono Chem Co., Ltd., founded in 2014, is a holding enterprise of Hongkong Pioneer Biotech Group. It is an export-oriented manufacturing enterprise supported by the Ministry of Commerce. Kono Chem is located in Xi'an, Shaanxi Province,

2,3-Dichloropyrazine(2,3-DCP)CAS 4858-85-9

Cas:4858-85-9

Min.Order:100 Kilogram

FOB Price: $80.0 / 100.0

Type:Other

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,3-Dichloropyrazine supplier in China

Cas:4858-85-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Manufacturer supply 2,3-Dichloropyrazine CAS 4858-85-9 with good quality Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/F

Manufacturer supply 2,3-Dichloropyrazine CAS 4858-85-9 with good quality

Cas:4858-85-9

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production Cyromazine、lead diacetate trihydrate /Lead acetate trihydrateC、 2-phenylacetamide 、 4-Aminophenyl-1-phenethylpiperidine 、Citric acid monohydrate 、 Citric acid/c

High quality 2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,3-dichloropyrazine

Cas:4858-85-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 4858-85-9 2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

2,3-Dichloropyrazine -- CHemwill

Cas:4858-85-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2,3-Dichloropyrazine 4858-85-9

Cas:4858-85-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 4858-85-9 with fast shipping

Cas:4858-85-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFUCHEM--4858-85-9--2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,3-Dichloropyrazine 4858-85-9

Cas:4858-85-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

About us Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad.

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:1 Kilogram

FOB Price: $200.0 / 230.0

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:white powder/crystal Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/A

2,3-dichloropyrazine

Cas:4858-85-9

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2,3-DICHLOROPYRAZINE

Cas:4858-85-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:clear colorless to light yellow liquid Storage:Well-sealed and put in dry and cool conditions. Protected from direct sunlight or high temperature. Package:as per your request A

2,3-Dichloropyrazine.

Cas:4858-85-9

Min.Order:500 Kilogram

Negotiable

Type:Trading Company

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2,3-Dichloropyrazine

Cas:4858-85-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2,3-Dichloropyrazine CAS No.:4858-85-9 Molecule Formula:C4H2Cl2N2 Molecule Weight:148.97 Purity: 96% Package: 25kg/drum Description:Light yellow transparent liquid Manufacture Standards:Enterprise Standard TESTING I

High Quality 2,3-Dichloropyrazine in stock

Cas:4858-85-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

DichloropyrazineCAS NO.: 4858-85-9

Cas:4858-85-9

Min.Order:1 Gram

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

Synthetic route

2-chloropyrazin
14508-49-7

2-chloropyrazin

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

Conditions
ConditionsYield
Stage #1: 2-chloropyrazin With 2,2,6,6-tetramethyl-piperidine; n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h;
Stage #2: With hexachloroethane In tetrahydrofuran; hexane at -78℃; for 1h;
90%
With sulfuryl dichloride In N,N-dimethyl-formamide81%
2,3-dihydroxypirazine
931-18-0

2,3-dihydroxypirazine

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

Conditions
ConditionsYield
With trichlorophosphate84%
3-chloropyrazine 1-oxide
6863-76-9

3-chloropyrazine 1-oxide

A

2,5-dichloropyrazine
19745-07-4

2,5-dichloropyrazine

B

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

C

2,6-dichloropyrazine
4774-14-5

2,6-dichloropyrazine

Conditions
ConditionsYield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given;
With 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given;
Pyrazin-N.N'-dioxyd
2423-84-9

Pyrazin-N.N'-dioxyd

A

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

B

2,6-dichloropyrazine
4774-14-5

2,6-dichloropyrazine

Conditions
ConditionsYield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
3-chloropyrazine 1-oxide
6863-76-9

3-chloropyrazine 1-oxide

A

2-chloropyrazin
14508-49-7

2-chloropyrazin

B

2,5-dichloropyrazine
19745-07-4

2,5-dichloropyrazine

C

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

D

2,6-dichloropyrazine
4774-14-5

2,6-dichloropyrazine

Conditions
ConditionsYield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
2-chloropyrazine 1-oxide
16025-16-4

2-chloropyrazine 1-oxide

A

2-chloropyrazin
14508-49-7

2-chloropyrazin

B

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

C

2,6-dichloropyrazine
4774-14-5

2,6-dichloropyrazine

Conditions
ConditionsYield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
2-chloropyrazin
14508-49-7

2-chloropyrazin

A

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

B

2,6-dichloro-pyrazine and 2,5-dichloro-pyrazine

2,6-dichloro-pyrazine and 2,5-dichloro-pyrazine

Conditions
ConditionsYield
With chlorine at 475℃;
1,4-pyrazine
290-37-9

1,4-pyrazine

water
7732-18-5

water

chlorine
7782-50-5

chlorine

A

2-chloropyrazin
14508-49-7

2-chloropyrazin

B

2,5-dichloropyrazine
19745-07-4

2,5-dichloropyrazine

C

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

D

2,6-dichloropyrazine
4774-14-5

2,6-dichloropyrazine

Conditions
ConditionsYield
at 350℃; Product distribution;
1,4-pyrazine
290-37-9

1,4-pyrazine

A

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

B

chloropyrazine, 2,6-dichloro-pyrazine, 2,5-dichloro-pyrazine

chloropyrazine, 2,6-dichloro-pyrazine, 2,5-dichloro-pyrazine

Conditions
ConditionsYield
With water; chlorine at 350℃;
With water; chlorine at 400 - 500℃;
With water; chlorine at 400 - 500℃;
3-chloropyrazine 1-oxide
6863-76-9

3-chloropyrazine 1-oxide

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

Conditions
ConditionsYield
With trichlorophosphate at 60℃; for 1h; Heating / reflux;
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

3-chloropyrazin-2-amine
6863-73-6

3-chloropyrazin-2-amine

Conditions
ConditionsYield
With ammonia In water at 100℃; for 18h; sealed tube;100%
With ammonium hydroxide In water at 100℃; for 24h;90%
With ammonium hydroxide In tetrahydrofuran at 100℃; for 18h;90%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

(3R)-3-Methyl-1-Tritylpiperazine
313657-75-9

(3R)-3-Methyl-1-Tritylpiperazine

(R)-1-(3-chloro-2-pyrazinyl)-2-methyl-4-tritylpiperazine
531503-76-1

(R)-1-(3-chloro-2-pyrazinyl)-2-methyl-4-tritylpiperazine

Conditions
ConditionsYield
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 127 - 133℃; for 41.5h;100%
With potassium carbonate In N,N-dimethyl-formamide at 100 - 110℃; for 20h;70.8%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

2-chloro-3-hydrazinopyrazine
63286-28-2

2-chloro-3-hydrazinopyrazine

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine With hydrazine hydrate In ethanol for 6h; Reflux;
Stage #2: With hydrazine hydrate In ethanol for 1h; Reflux;
100%
With hydrazine hydrate In ethanol; water Reflux;96%
With hydrazine In ethanol at 80℃; for 1h;93%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

2-phenoxyethanamine
1758-46-9

2-phenoxyethanamine

2-Chloro-3-(2-phenoxyethylamino)pyrazine
313654-73-8

2-Chloro-3-(2-phenoxyethylamino)pyrazine

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 180℃; for 0.333333h; microwave irradiation;100%
With potassium carbonate In hexane; ethyl acetate; acetonitrile2.36 g (49%)
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

2,4-Dimethoxybenzylamine
20781-20-8

2,4-Dimethoxybenzylamine

3-chloro-N-[(2,4-dimethoxyphenyl)methyl]pyrazin-2-amine
1190969-75-5

3-chloro-N-[(2,4-dimethoxyphenyl)methyl]pyrazin-2-amine

Conditions
ConditionsYield
100%
at 20℃; for 16h;
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

pinacol benzylboronate
87100-28-5

pinacol benzylboronate

2-benzyl-3-chloropyrazine
57693-15-9

2-benzyl-3-chloropyrazine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In water; acetonitrile at 150℃; for 0.166667h; Inert atmosphere; Microwave irradiation;100%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

4-chloro-phenol
106-48-9

4-chloro-phenol

C9H5Cl2N3O

C9H5Cl2N3O

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 15h;100%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

4-chloro-phenol
106-48-9

4-chloro-phenol

2-chloro-3-(4-chlorophenoxy)pyrazine

2-chloro-3-(4-chlorophenoxy)pyrazine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 15h;100%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

potassium tert-butylate
865-47-4

potassium tert-butylate

2-(tert-butoxy)-3-chloropyrazine

2-(tert-butoxy)-3-chloropyrazine

Conditions
ConditionsYield
In tetrahydrofuran for 1h; Inert atmosphere; Cooling with ice;100%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

m-tolylboronic acid
17933-03-8

m-tolylboronic acid

2,3-di-m-tolylpyrazine

2,3-di-m-tolylpyrazine

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine; m-tolylboronic acid With tetrakis(triphenylphosphine) palladium(0) In water; toluene at 95℃; for 0.166667h; Suzuki Coupling; Inert atmosphere;
Stage #2: With potassium fluoride dihydrate In water; toluene at 95℃; Suzuki Coupling; Inert atmosphere;
99%
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In water; acetonitrile for 3.66667h;80%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

ditetrazolo<1,5-a:5',1'c>pyrazine
126229-04-7

ditetrazolo<1,5-a:5',1'c>pyrazine

Conditions
ConditionsYield
With sodium azide In dimethyl sulfoxide at 20℃; for 48h;98%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

Isobutyronitrile
78-82-0

Isobutyronitrile

2-(3-chloropyrazin-2-yl)-2-methylpropanenitrile

2-(3-chloropyrazin-2-yl)-2-methylpropanenitrile

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine With lithium hexamethyldisilazane In toluene
Stage #2: Isobutyronitrile In toluene at 20℃; for 24h;
98%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

propyl cyanide
109-74-0

propyl cyanide

2-(3-chloropyrazin-2-yl)butanenitrile
914360-89-7

2-(3-chloropyrazin-2-yl)butanenitrile

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine With lithium hexamethyldisilazane In toluene
Stage #2: propyl cyanide In toluene at 20℃; for 24h;
98%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

4-trifluoromethylphenylboronic acid
128796-39-4

4-trifluoromethylphenylboronic acid

2,3-bis(4-(trifluoromethyl)phenyl)pyrazine

2,3-bis(4-(trifluoromethyl)phenyl)pyrazine

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine; 4-trifluoromethylphenylboronic acid With tetrakis(triphenylphosphine) palladium(0) In water; toluene at 95℃; for 0.166667h; Suzuki Coupling; Inert atmosphere;
Stage #2: With potassium fluoride dihydrate In water; toluene at 95℃; Suzuki Coupling; Inert atmosphere;
98%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

phenylboronic acid
98-80-6

phenylboronic acid

2,3-diphenylpyrazine
1588-89-2

2,3-diphenylpyrazine

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine; phenylboronic acid With tetrakis(triphenylphosphine) palladium(0) In water; toluene at 95℃; for 0.166667h; Suzuki Coupling; Inert atmosphere;
Stage #2: With potassium fluoride dihydrate In water; toluene at 95℃; Suzuki Coupling; Inert atmosphere;
97%
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In water; acetonitrile Suzuki coupling;74%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

2,3-bis(p-methylphenyl)pyrazine
92405-82-8

2,3-bis(p-methylphenyl)pyrazine

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine; 4-methylphenylboronic acid With tetrakis(triphenylphosphine) palladium(0) In water; toluene at 95℃; for 0.166667h; Suzuki Coupling; Inert atmosphere;
Stage #2: With potassium fluoride dihydrate In water; toluene at 95℃; Suzuki Coupling; Inert atmosphere;
97%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

tert-butyl (1,3-cis)-N-(3-hydroxycyclobutyl)carbamate
389890-43-1

tert-butyl (1,3-cis)-N-(3-hydroxycyclobutyl)carbamate

tert-butyl ((1S,3S)-3-((3-chloropyrazin-2-yl)oxy)cyclobutyl)carbamate
1349184-47-9

tert-butyl ((1S,3S)-3-((3-chloropyrazin-2-yl)oxy)cyclobutyl)carbamate

Conditions
ConditionsYield
With caesium carbonate In dimethyl sulfoxide at 80℃;96.6%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

1-thiopropane
107-03-9

1-thiopropane

2-chloro-3-(propylthio)pyrazine
685872-18-8

2-chloro-3-(propylthio)pyrazine

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; for 2h;96%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

butyrophenone
495-40-9

butyrophenone

2-(3-chloropyrazin-2-yl)-1-phenylbutan-1-one
914360-74-0

2-(3-chloropyrazin-2-yl)-1-phenylbutan-1-one

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine With lithium hexamethyldisilazane In toluene
Stage #2: propiophenone In toluene at 60℃; for 24h;
96%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

sulfanilamide
63-74-1

sulfanilamide

4-amino-N-(3-chloro-pyrazin-2-yl)-benzenesulfonamide
14423-79-1

4-amino-N-(3-chloro-pyrazin-2-yl)-benzenesulfonamide

Conditions
ConditionsYield
With potassium carbonate In N-methyl-acetamide; water; toluene95%
With potassium carbonate
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

acetonitrile
75-05-8

acetonitrile

(3-chloropyrazin-2-yl)acetonitrile

(3-chloropyrazin-2-yl)acetonitrile

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine With lithium hexamethyldisilazane In toluene
Stage #2: acetonitrile In toluene at 20℃; for 24h;
95%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

N-aminopyridin-1-ium iodide
6295-87-0

N-aminopyridin-1-ium iodide

N-(3'-chloropyrazin-2'-yl)pyridinium aminide

N-(3'-chloropyrazin-2'-yl)pyridinium aminide

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 20h; Heating;95%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate
124443-68-1

1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate

1-tert-butyl 4-methyl 4-(3-chloropyrazin-2-yl)piperidine-1,4-dicarboxylate
1227068-50-9

1-tert-butyl 4-methyl 4-(3-chloropyrazin-2-yl)piperidine-1,4-dicarboxylate

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at 20℃; for 16h; Inert atmosphere;95%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

10H-benzo[b]pyrazino[2,3-e][1,4]thiazine
37693-82-6

10H-benzo[b]pyrazino[2,3-e][1,4]thiazine

Conditions
ConditionsYield
With potassium hydroxide In water; N,N-dimethyl-formamide for 4h; Heating;94%
With sodium carbonate In 1,2-dichloro-benzene Heating;
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

1,1'-bis[4-(dimethylamino)(pyrazine-2,3-diyl)pyridinium]dichloride

1,1'-bis[4-(dimethylamino)(pyrazine-2,3-diyl)pyridinium]dichloride

Conditions
ConditionsYield
In 1,2-dichloro-benzene at 140℃; for 1h;94%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

4-aminomethyl-piperidine-1-carboxylic acid benzyl ester
157023-34-2

4-aminomethyl-piperidine-1-carboxylic acid benzyl ester

benzyl 4-{[(3-chloropyrazin-2-yl)amino]methyl}piperidine-1-carboxylate
455265-59-5

benzyl 4-{[(3-chloropyrazin-2-yl)amino]methyl}piperidine-1-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 72h; Heating;94%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

2,3-bis(4-fluorophenyl)pyrazine
909567-96-0

2,3-bis(4-fluorophenyl)pyrazine

Conditions
ConditionsYield
Stage #1: 2,3-dichloropyrazine; 4-fluoroboronic acid With tetrakis(triphenylphosphine) palladium(0) In water; toluene at 95℃; for 0.166667h; Suzuki Coupling; Inert atmosphere;
Stage #2: With potassium fluoride dihydrate In water; toluene at 95℃; Suzuki Coupling; Inert atmosphere;
94%
1,3 dithiane
505-23-7

1,3 dithiane

2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

methyl iodide
74-88-4

methyl iodide

2-chloro-3-(2-methyl-1,3-dithian-2-yl)pyrazine
1131041-56-9

2-chloro-3-(2-methyl-1,3-dithian-2-yl)pyrazine

Conditions
ConditionsYield
Stage #1: 1,3 dithiane With n-butyllithium In tetrahydrofuran at -20℃; for 1h;
Stage #2: methyl iodide In tetrahydrofuran at -50 - 20℃;
Stage #3: 2,3-dichloropyrazine With n-butyllithium In tetrahydrofuran at -50 - 20℃;
93%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

diphenylamine
122-39-4

diphenylamine

5-phenyl-5H-pyrazino[2,3-b]indole
1202362-87-5

5-phenyl-5H-pyrazino[2,3-b]indole

Conditions
ConditionsYield
With palladium diacetate; sodium t-butanolate; tricyclohexylphosphine In toluene at 105℃; for 18h; Inert atmosphere; regioselective reaction;93%
2,3-dichloropyrazine
4858-85-9

2,3-dichloropyrazine

methylamine
74-89-5

methylamine

3-chloro-N-methylpyrazin-2-amine

3-chloro-N-methylpyrazin-2-amine

Conditions
ConditionsYield
In ethanol at 80℃; for 0.5h; Inert atmosphere; Sealed tube;93%
In tetrahydrofuran; dichloromethane43.6%
In tetrahydrofuran at 20℃; for 24h;43.6%
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