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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2(5H)-Furanone Manufacturer/High quality/Best price/In stock

Cas:497-23-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2(5H)-Furanone supplier in China

Cas:497-23-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% gamma-crotonolactone 497-23-4 Producer

Cas:497-23-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2(5H)-Furanone

Cas:497-23-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

2(5H)-Furanone Basic information Product Name: 2(5H)-Furanone Synonyms: .alpha.,.beta.-Crotonolactone;.delta.,.alpha.,.beta.-Butenolide;.gamma.-Crotolactone;.gamma.-Hydroxycrotonicacidla

2(5H)-Furanone 497-23-4

Cas:497-23-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

gamma-crotonolactone

Cas:497-23-4

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Hot CAS 497-23-4 with best quality

Cas:497-23-4

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

2(5H)-Furanone 99%

Cas:497-23-4

Min.Order:1 Kilogram

FOB Price: $42.0 / 56.0

Type:Trading Company

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Hubei Jiutian Bio-medical Technology Co., Ltd

Name: 2(5H)-Furanone Synonyms: 2-b4o; c4h4o2; C17601; 4285AE; AN-650; K-9234; 497f234; RP08216; ST092353; S14-1197; AC1L1UZZ; LS-70308; BC201413; ACT09335; CJ-27710; SC-50260; CJ-06322; nsc51296; AK163254; NSC 51296; nsc197009; nsc-51296; KSC235S1R;

furan-2(5H)-one 497-23-4

Cas:497-23-4

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

High quality 2(5H)-Furanone supplier in China CAS NO.497-23-4

Cas:497-23-4

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2(5H)-Furanone

Cas:497-23-4

Min.Order:0

Negotiable

Type:Manufacturers

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HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:Light brown liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:2-Furanone is a heterocyclic organic compound that

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply gamma-crotonolactone

Cas:497-23-4

Min.Order:0 Metric Ton

Negotiable

Type:Other

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JINING XINHE CHEMICAL CO., LTD

Advantage 1: The product passed the professional production process and quality inspection, the purity is 99% +. 2: Highly qualified engineers to provide technical documents and service. 3: We could provide sample for your test. 4: High qualit

2(5H)-Furanone 497-23-4

Cas:497-23-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2(5H)-Furanone/High quality/Best price

Cas:497-23-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

2(5H)-Furanone Basic information Product Name: 2(5H)-Furanone CAS: 497-23-4 MF: C4H4O2 MW: 84.07 EINECS: 207-839-3 Mol File: 497-23-4.mol Appearance:Colorless Clea

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

2(5H)-Furanone 497-23-4CAS NO.: 497-23-4

Cas:497-23-4

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

2(5H)-Furanone Chemical Properties Melting point 4-5 °C (lit.) Boiling point 86-87 °C/12 mmHg (lit.) density 1.185 g/mL at 25 °C (lit.) FEMA 4138 | 4-HYDROXY-2-BUTENOIC ACID GAMMA-LACTONE refractive index n20/D 1.469(l

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

DescriptionFeedback 2-Furanone, also known as γ-crotonolactone (GCL), is a heterocyclic organic compound. Classified as a lactone, this colourless liquid is colloquially called "butenolide." As a class

2(5H)-Furanone

Cas:497-23-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

γ-Crotonolactone

Cas:497-23-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

High quality 2(5H)-Furanone supplier in China CAS NO.497-23-4 CAS NO.497-23-4

Cas:497-23-4

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

2(5H)-Furanone

Cas:497-23-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2(5H)-Furanone

Cas:497-23-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

gamma-crotonolactoneAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

gamma-crotonolactone

Cas:497-23-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2(5H)-Furanone

Cas:497-23-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

gamma-crotonolactone

Cas:497-23-4

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

1,4-butenediol
6117-80-2

1,4-butenediol

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With 5 wt% Pd nanoparticles loaded on phosphate anion exchanged [Mg6Al2(OH)16]CO3*xH2O; air at 50℃; under 760.051 Torr; for 6h; Reagent/catalyst; Irradiation;100%
With Celite; silver carbonate In benzene for 2h; Heating;78%
With allyl methyl carbonate; dihydridotetrakis(triphenylphosphine)ruthenium In toluene for 6h; Heating;77%
at 30℃; for 24h; Nocardia corallina B-276;50%
With sodium hydrogencarbonate; sodium carbonate at 20℃; for 3h; anodic oxidation on PbO2;
(E/Z)-trimethylsilyl 4-bromo-2-butenoate

(E/Z)-trimethylsilyl 4-bromo-2-butenoate

A

trimethylsilyl bromide
2857-97-8

trimethylsilyl bromide

B

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
at 140 - 170℃; for 1h;A 98%
B 80%
η-allylcarboxylatoruthenium(II) complex RuC3H4CO2(P(C6H4-p-Cl)3)2(CO)

η-allylcarboxylatoruthenium(II) complex RuC3H4CO2(P(C6H4-p-Cl)3)2(CO)

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With bromine In dichloromethane Ambient temperature;93%
but-3-enoic acid
625-38-7

but-3-enoic acid

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
Stage #1: but-3-enoic acid With Oxalyl bromide; dimethyl sulfoxide In dichloromethane at -10 - 20℃; Inert atmosphere;
Stage #2: With potassium carbonate In dichloromethane; water for 6h;
92%
With ammonium iodide; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid In 2,2,2-trifluoroethanol; acetonitrile at 20℃; for 24h;63%
With [bis(acetoxy)iodo]benzene; lithium bromide In methanol at 20℃; for 1h;60%
2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With oxygen In toluene at 80℃; for 2.5h;91%
With 1-methyl-1H-imidazole; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate In acetonitrile at 22℃; for 6h; Reagent/catalyst;80%
With [{Cu2(5-phenyl-2,8-bis(6′-bipyridinyl)-1,9,10-anthyridine)-(μ-ClO4)2}(PF6)2]; dihydrogen peroxide; sodium acetate In water at 70℃; for 12h;63%
3-hydroxyoxolan-2-one
19444-84-9

3-hydroxyoxolan-2-one

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With sulfuric acid; acetic anhydride at 0℃; for 0.25h;90%
Stage #1: 3-hydroxyoxolan-2-one With sulfuric acid; acetic anhydride at 0℃; for 0.25h;
Stage #2: With dmap at 100℃; for 3h;
90%
η-allylcarboxylatoruthenium(II) complex RuC3H4CO2(PPh3)2(CO)

η-allylcarboxylatoruthenium(II) complex RuC3H4CO2(PPh3)2(CO)

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With bromine In dichloromethane Ambient temperature;86%
2,5-diacetoxy-2,5-dihydrofuran
7093-88-1

2,5-diacetoxy-2,5-dihydrofuran

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With hydrogenchloride In water; acetone at 20℃; for 12h;86%
2,5-dihydro-2,5-dimethoxyfuran
332-77-4

2,5-dihydro-2,5-dimethoxyfuran

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With hydrogenchloride In water; acetone at 20℃; for 16h;84%
With trimethylsilyl bromide In dichloromethane at 20℃;
2-ethoxy-2,5-dimethyl-2,5-dihydrofuran
20295-21-0

2-ethoxy-2,5-dimethyl-2,5-dihydrofuran

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With sulfuric acid In water; acetone at 20℃; for 12h;82%
2,5-diisopropyl-2,5-dihydrofuran
20295-22-1

2,5-diisopropyl-2,5-dihydrofuran

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With nitric acid In water; acetone at 20℃; for 12h;81%
2,5-n-butoxy-2,5-dihydrofuran
20295-23-2

2,5-n-butoxy-2,5-dihydrofuran

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With phosphoric acid In water; acetone at 20℃; for 12h;79%
Acetyl-L-carnitine
3040-38-8

Acetyl-L-carnitine

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
In acetonitrile for 24h; Heating;77%
1-iodo-butane
542-69-8

1-iodo-butane

(furan-2-yloxy)-trimethylsilane
61550-02-5

(furan-2-yloxy)-trimethylsilane

silver trifluoroacetate
2966-50-9

silver trifluoroacetate

A

5-butylfuran-2(5H)-one
30336-14-2

5-butylfuran-2(5H)-one

B

n-butyl trifluoroacetate
367-64-6

n-butyl trifluoroacetate

C

4-oxo-octanoic acid butyl ester
18688-70-5

4-oxo-octanoic acid butyl ester

D

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
In dichloromethane 1.) -78 deg C, 2.) to 10 deg C, 4 h; Further byproducts given. Title compound not separated from byproducts;A 76%
B n/a
C 3%
D n/a
(furan-2-yloxy)-trimethylsilane
61550-02-5

(furan-2-yloxy)-trimethylsilane

silver trifluoroacetate
2966-50-9

silver trifluoroacetate

A

5-butylfuran-2(5H)-one
30336-14-2

5-butylfuran-2(5H)-one

B

n-butyl trifluoroacetate
367-64-6

n-butyl trifluoroacetate

C

2-buten-4-olide
497-23-4

2-buten-4-olide

D

3-butylfuran-2(3H)-one
124083-30-3

3-butylfuran-2(3H)-one

Conditions
ConditionsYield
With 1-iodo-butane In dichloromethane 1.) -78 deg C, 2.) to 10 deg C, 4 h; Further byproducts given. Title compound not separated from byproducts;A 76%
B n/a
C n/a
D n/a
carbon monoxide
201230-82-2

carbon monoxide

(Z)-3-iodoprop-2-en-1-ol
37428-57-2, 71065-45-7, 37428-50-5

(Z)-3-iodoprop-2-en-1-ol

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With potassium carbonate; hydrazine; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran at 25℃; under 760 Torr; for 72h;76%
2,5-bis(2-hydroxyethoxy)-2,5-dihydrofuran

2,5-bis(2-hydroxyethoxy)-2,5-dihydrofuran

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With acetic acid In water; acetone at 20℃; for 12h;73%
α-phenylsulfinyl-γ-butyrolactone
54144-98-8

α-phenylsulfinyl-γ-butyrolactone

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
In neat (no solvent) at 120℃; under 0.05 - 0.1 Torr; for 2h;72%
carbon monoxide
201230-82-2

carbon monoxide

acetylene
74-86-2

acetylene

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With hexarhodium hexadecacarbonyl; water; triethylamine In 1,4-dioxane at 50℃; under 76000 Torr; for 5h;71%
furfural
98-01-1

furfural

A

2-buten-4-olide
497-23-4

2-buten-4-olide

B

maleic acid
110-16-7

maleic acid

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid In water at 60℃; for 24h; Green chemistry;A 71%
B 11%
With dihydrogen peroxide; potassium bromide; potassium hydroxide In water at 100℃; for 3h; Concentration;A 7.1%
B 51.9%
furfural
98-01-1

furfural

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With niobium(V) acetate tetrahydrate; dihydrogen peroxide In water at 60℃; for 84h;64%
With formic acid; water; dihydrogen peroxide; sodium sulfate In ethyl acetate at 260℃; under 760.051 Torr; for 2.5h; Solvent; Reagent/catalyst;62%
With 2-(N,N-dimethylamino)ethanol; formic acid; dihydrogen peroxide; sodium sulfate In dichloromethane; water at 20℃; for 15h; Inert atmosphere;58%
2,2'-ethane-1,2-diylbissulfanyl-bis-ethanol
5244-34-8

2,2'-ethane-1,2-diylbissulfanyl-bis-ethanol

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With pyridine; toluene-4-sulfonic acid In methanol63%
furfural
98-01-1

furfural

A

succinic acid
110-15-6

succinic acid

B

2-buten-4-olide
497-23-4

2-buten-4-olide

C

maleic acid
110-16-7

maleic acid

Conditions
ConditionsYield
With formic acid; dihydrogen peroxide; sodium sulfate In water; ethyl acetate at 59.84℃; for 3h; Kinetics; Solvent; Reagent/catalyst; Temperature; Concentration;A 8.5%
B 61.5%
C 6.7%
With potassium chloride; dihydrogen peroxide; potassium hydroxide In water at 100℃; for 3h; Reagent/catalyst;A 24.2%
B 10.4%
C 41.2%
With formic acid; dihydrogen peroxide; sodium sulfate In water at 59.84℃; for 3h; Kinetics; Solvent; Reagent/catalyst;A 38.3%
B 12.8%
C 17.3%
2-pentanol
584-02-1

2-pentanol

D-erythronolactone
15667-21-7

D-erythronolactone

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With methyltrioxorhenium(VII) at 155℃; for 2.5h; Inert atmosphere;57%
methacryloyl anhydride
760-93-0

methacryloyl anhydride

(3S)-hydroxy-γ-butyrolactone
5469-16-9, 58081-05-3, 131432-37-6, 7331-52-4

(3S)-hydroxy-γ-butyrolactone

A

γ-butyrolactone-3-yl methacrylate

γ-butyrolactone-3-yl methacrylate

B

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With 2,6-di-tert-butyl-4-methyl-phenol; sodium carbonate In toluene at 50℃; for 4h; Reagent/catalyst;A 55%
B 21%
4-bromomethyl-β-lactone
33282-42-7

4-bromomethyl-β-lactone

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With silver nitrate In acetic acid Heating;53%
With silver nitrate In acetic acid Heating; other γ-bromo β-lactones;53%
carbon monoxide
201230-82-2

carbon monoxide

acetylene
74-86-2

acetylene

A

4-butanolide
96-48-0

4-butanolide

B

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With water; triethylamine; (acetylacetonato)dicarbonylrhodium (l) In 1,4-dioxane at 20 - 120℃; under 2700.27 - 186019 Torr; for 2h;A 22%
B 52%
With water; triethylamine; (acetylacetonato)dicarbonylrhodium (l) In 1,4-dioxane at 20 - 120℃; under 2700.27 - 186019 Torr; for 2h;
5-hydroxydihydrofuran-2(3H)-one
50768-69-9

5-hydroxydihydrofuran-2(3H)-one

A

2-buten-4-olide
497-23-4

2-buten-4-olide

B

acrolein
107-02-8

acrolein

Conditions
ConditionsYield
at 300℃; under 760.051 Torr; for 3h; Reagent/catalyst; Temperature; Inert atmosphere;A 51.4%
B n/a
3(S)-amino-γ-butyrolactone·hydrobromide
104323-16-2

3(S)-amino-γ-butyrolactone·hydrobromide

A

4-Hydroxy-dihydro-furan-2-on
5469-16-9, 7331-52-4, 58081-05-3, 131432-37-6

4-Hydroxy-dihydro-furan-2-on

B

2-buten-4-olide
497-23-4

2-buten-4-olide

Conditions
ConditionsYield
With sodium nitroprusside; potassium carbonateA 50%
B 17%
pyrrolidine
123-75-1

pyrrolidine

2-buten-4-olide
497-23-4

2-buten-4-olide

4-pyrrolidin-1-yl-dihydrofurran-2-one

4-pyrrolidin-1-yl-dihydrofurran-2-one

Conditions
ConditionsYield
In dichloromethane for 1h; Ambient temperature;100%
In chloroform-d1 at 26.9℃; addition of bicyclic chiral guanidinium salts; reaction half life; other solvent;
With complex receptor In chloroform
piperonal
120-57-0

piperonal

2-buten-4-olide
497-23-4

2-buten-4-olide

(3,4-dimethoxybenzyl)(phenyl)sulfane
83318-94-9

(3,4-dimethoxybenzyl)(phenyl)sulfane

3-(3'',4''-dimethoxy-α-phenylthiobenzyl)-2-(α-hydroxy-3',4'-methylenedioxybenzyl)-γ-butyrolactone
118535-07-2, 118626-85-0, 118711-47-0

3-(3'',4''-dimethoxy-α-phenylthiobenzyl)-2-(α-hydroxy-3',4'-methylenedioxybenzyl)-γ-butyrolactone

Conditions
ConditionsYield
100%
With n-butyllithium 1.) THF, -78 deg C, 3 h; 2.) THF, -78 deg C, 40 min; 3.) THF, -78 deg C, 90 min; Yield given. Multistep reaction;
2-buten-4-olide
497-23-4

2-buten-4-olide

benzylamine
100-46-9

benzylamine

(R,S)-4-benzylamino-4,5-dihydro-2(3H)-furanone
127560-92-3

(R,S)-4-benzylamino-4,5-dihydro-2(3H)-furanone

Conditions
ConditionsYield
In dichloromethane for 1h; Ambient temperature;100%
In methanol at 0℃; for 24h;60%
In methanol at 0℃; for 24h;50%
2-buten-4-olide
497-23-4

2-buten-4-olide

isopropyl alcohol
67-63-0

isopropyl alcohol

4-(1-hydroxy-1-methylethyl)tetrahydrofuran-2-one
42867-48-1

4-(1-hydroxy-1-methylethyl)tetrahydrofuran-2-one

Conditions
ConditionsYield
for 13h; Inert atmosphere; Irradiation;100%
With bis(p-methoxyphenyl)methanone UV-irradiation;94%
With bis(p-methoxyphenyl)methanone for 0.166667h; UV-irradiation; Continuous-flow microreactor; Inert atmosphere; diastereoselective reaction;100 %Spectr.
2-buten-4-olide
497-23-4

2-buten-4-olide

4-butanolide
96-48-0

4-butanolide

Conditions
ConditionsYield
With hydrogen In methanol under 26252.6 Torr; for 2h; Reagent/catalyst; Autoclave;99%
With 0.5% palladium on silica gel; hydrogen In methanol at 80℃; under 26252.6 Torr; Catalytic behavior; Kinetics; Reagent/catalyst; Autoclave;92.6%
With Ni#NiO; hydrogen In ethanol at 80℃; under 22502.3 Torr; for 1h; Reagent/catalyst; Autoclave;86.6%
(E)-3-(4-chlorophenyl)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one

(E)-3-(4-chlorophenyl)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one

2-buten-4-olide
497-23-4

2-buten-4-olide

(S)-5-((S)-1-(4-chlorophenyl)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-oxopropyl)furan-2(5H)-one

(S)-5-((S)-1-(4-chlorophenyl)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-oxopropyl)furan-2(5H)-one

Conditions
ConditionsYield
With (R)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(bis(3,5-di-t-butyl-4-methoxyphenyl))phosphine; tetrakis(actonitrile)copper(I) hexafluorophosphate; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine In tetrahydrofuran at -40℃; for 24h; enantioselective reaction;99%
(E)-3-(2-bromophenyl)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one

(E)-3-(2-bromophenyl)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one

2-buten-4-olide
497-23-4

2-buten-4-olide

(S)-5-((S)-1-(2-bromophenyl)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-oxopropyl)furan-2(5H)-one

(S)-5-((S)-1-(2-bromophenyl)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-oxopropyl)furan-2(5H)-one

Conditions
ConditionsYield
With (R)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(bis(3,5-di-t-butyl-4-methoxyphenyl))phosphine; tetrakis(actonitrile)copper(I) hexafluorophosphate; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine In tetrahydrofuran at -40℃; for 24h; enantioselective reaction;99%
(3-(2-methoxyethoxy)phenyl)boronic acid
227305-67-1

(3-(2-methoxyethoxy)phenyl)boronic acid

2-buten-4-olide
497-23-4

2-buten-4-olide

4-(3-(2-methoxyethoxy)phenyl)dihydrofuran-2(3H)-one

4-(3-(2-methoxyethoxy)phenyl)dihydrofuran-2(3H)-one

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl In 1,4-dioxane at 100℃; for 1h; Reagent/catalyst; Microwave irradiation;99%
C24H23NOS

C24H23NOS

2-buten-4-olide
497-23-4

2-buten-4-olide

(R)-N,N-dibenzyl-3-(2-methoxyphenyl)-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)propanethioamide
1638616-36-0

(R)-N,N-dibenzyl-3-(2-methoxyphenyl)-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)propanethioamide

Conditions
ConditionsYield
With tetrakis(actonitrile)copper(I) hexafluorophosphate; N-Methyldicyclohexylamine; (R)-segphos In tetrahydrofuran at 20℃; for 12h; Inert atmosphere; stereoselective reaction;98%
C23H20FNS

C23H20FNS

2-buten-4-olide
497-23-4

2-buten-4-olide

(R)-N,N-dibenzyl-3-(4-fluorophenyl)-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)propanethioamide
1638616-38-2

(R)-N,N-dibenzyl-3-(4-fluorophenyl)-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)propanethioamide

Conditions
ConditionsYield
With tetrakis(actonitrile)copper(I) hexafluorophosphate; N-Methyldicyclohexylamine; (R)-segphos In tetrahydrofuran at 20℃; for 6h; Inert atmosphere; stereoselective reaction;98%
2-buten-4-olide
497-23-4

2-buten-4-olide

N,N-dimethylthiocrotonic amide

N,N-dimethylthiocrotonic amide

(S)-N,N-dimethyl-3-((R)-5-oxo-2,5-dihydrofuran-2-yl)butanethioamide
1638616-44-0

(S)-N,N-dimethyl-3-((R)-5-oxo-2,5-dihydrofuran-2-yl)butanethioamide

Conditions
ConditionsYield
With tetrakis(actonitrile)copper(I) hexafluorophosphate; N-Methyldicyclohexylamine; (R)-segphos In tetrahydrofuran at 20℃; for 24h; Inert atmosphere; stereoselective reaction;98%
(E)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-phenylprop-2-en-1-one

(E)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-phenylprop-2-en-1-one

2-buten-4-olide
497-23-4

2-buten-4-olide

(S)-5-((S)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-oxo-1-phenylpropyl)furan-2(5H)-one

(S)-5-((S)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-oxo-1-phenylpropyl)furan-2(5H)-one

Conditions
ConditionsYield
With (R)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(bis(3,5-di-t-butyl-4-methoxyphenyl))phosphine; tetrakis(actonitrile)copper(I) hexafluorophosphate; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine In tetrahydrofuran at -40℃; for 3h; enantioselective reaction;98%
1-aminodecane
2016-57-1

1-aminodecane

2-buten-4-olide
497-23-4

2-buten-4-olide

N-Decyl-3-decylamino-4-hydroxy-butyramide
104053-25-0

N-Decyl-3-decylamino-4-hydroxy-butyramide

Conditions
ConditionsYield
97%
In acetonitrile for 24h; Reflux;68%
1-Heptylamine
111-68-2

1-Heptylamine

2-buten-4-olide
497-23-4

2-buten-4-olide

N-heptyl-3-heptylamino-4-hydroxybutanamide
182740-75-6

N-heptyl-3-heptylamino-4-hydroxybutanamide

Conditions
ConditionsYield
In chloroform for 24h;97%
triisopropylsilyl trifluoromethanesulfonate
80522-42-5

triisopropylsilyl trifluoromethanesulfonate

2-buten-4-olide
497-23-4

2-buten-4-olide

(furan-2-yloxy)triisopropylsilane
171201-21-1

(furan-2-yloxy)triisopropylsilane

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 2.5h; Inert atmosphere;97%
With N-ethyl-N,N-diisopropylamine In dichloromethane 0 deg C to r.t.;95%
With triethylamine In dichloromethane at 0 - 20℃; for 5h; Inert atmosphere;94%
2-buten-4-olide
497-23-4

2-buten-4-olide

benzylamine
100-46-9

benzylamine

3-benzylamino-4-hydroxy-N-benzylbutanamide
169677-08-1

3-benzylamino-4-hydroxy-N-benzylbutanamide

Conditions
ConditionsYield
In chloroform for 24h;97%
C9H11NS2

C9H11NS2

2-buten-4-olide
497-23-4

2-buten-4-olide

(S)-N,N-dimethyl-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)-3-(thiophen-2-yl)propanethioamide
1638616-41-7

(S)-N,N-dimethyl-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)-3-(thiophen-2-yl)propanethioamide

Conditions
ConditionsYield
With tetrakis(actonitrile)copper(I) hexafluorophosphate; N-Methyldicyclohexylamine; (R)-segphos In tetrahydrofuran at 20℃; for 12h; Inert atmosphere; stereoselective reaction;97%
(E)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-(4-fluorophenyl)prop-2-en-1-one

(E)-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-3-(4-fluorophenyl)prop-2-en-1-one

2-buten-4-olide
497-23-4

2-buten-4-olide

(S)-5-((S)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-1-(4-fluorophenyl)-3-oxopropyl)furan-2(5H)-one

(S)-5-((S)-3-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)-1-(4-fluorophenyl)-3-oxopropyl)furan-2(5H)-one

Conditions
ConditionsYield
With (R)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(bis(3,5-di-t-butyl-4-methoxyphenyl))phosphine; tetrakis(actonitrile)copper(I) hexafluorophosphate; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine In tetrahydrofuran at -40℃; for 24h; enantioselective reaction;97%
2-buten-4-olide
497-23-4

2-buten-4-olide

ethylamine
75-04-7

ethylamine

N-Ethyl-3-ethylamino-4-hydroxy-butyramide
104053-23-8

N-Ethyl-3-ethylamino-4-hydroxy-butyramide

Conditions
ConditionsYield
Heating;96%
2-buten-4-olide
497-23-4

2-buten-4-olide

N-butylamine
109-73-9

N-butylamine

N-butyl-3-butylamino-4-hydroxybutanamide
104053-24-9

N-butyl-3-butylamino-4-hydroxybutanamide

Conditions
ConditionsYield
In chloroform for 24h;96%
Heating;94%
2-buten-4-olide
497-23-4

2-buten-4-olide

N,N-dimethylthiocinnamic amide

N,N-dimethylthiocinnamic amide

(R)-N,N-dimethyl-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)-3-phenylpropanethioamide
1638616-31-5

(R)-N,N-dimethyl-3-((S)-5-oxo-2,5-dihydrofuran-2-yl)-3-phenylpropanethioamide

Conditions
ConditionsYield
With tetrakis(actonitrile)copper(I) hexafluorophosphate; N-Methyldicyclohexylamine; (R)-segphos In tetrahydrofuran at 20℃; for 12h; Catalytic behavior; Reagent/catalyst; Time; Inert atmosphere; stereoselective reaction;96%
2-buten-4-olide
497-23-4

2-buten-4-olide

(4S,5S)-2-[N-(2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl)(methyl)amino]-2-(4-methoxyphenyl)acetonitrile
204439-58-7

(4S,5S)-2-[N-(2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl)(methyl)amino]-2-(4-methoxyphenyl)acetonitrile

prenyl bromide
870-63-3

prenyl bromide

(S)-[((4S,5S)-2,2-Dimethyl-4-phenyl-[1,3]dioxan-5-yl)-methyl-amino]-(4-methoxy-phenyl)-[(3R,4S)-4-(3-methyl-but-2-enyl)-5-oxo-tetrahydro-furan-3-yl]-acetonitrile

(S)-[((4S,5S)-2,2-Dimethyl-4-phenyl-[1,3]dioxan-5-yl)-methyl-amino]-(4-methoxy-phenyl)-[(3R,4S)-4-(3-methyl-but-2-enyl)-5-oxo-tetrahydro-furan-3-yl]-acetonitrile

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane at -30℃; for 4h;95%
2-buten-4-olide
497-23-4

2-buten-4-olide

1-amino-2-propene
107-11-9

1-amino-2-propene

N-Allyl-3-allylamino-4-hydroxy-butyramide

N-Allyl-3-allylamino-4-hydroxy-butyramide

Conditions
ConditionsYield
In chloroform for 24h;95%
2-buten-4-olide
497-23-4

2-buten-4-olide

triisopropylsilyl trifluoromethanesulfonate

triisopropylsilyl trifluoromethanesulfonate

(furan-2-yloxy)triisopropylsilane
171201-21-1

(furan-2-yloxy)triisopropylsilane

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 16h; Etherification; Aromatization;95%
(1S,4aS,8aS)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthaleneacetaldehyde
3243-36-5

(1S,4aS,8aS)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthaleneacetaldehyde

2-buten-4-olide
497-23-4

2-buten-4-olide

C20H30O3

C20H30O3

Conditions
ConditionsYield
Stage #1: 2-buten-4-olide With di-n-butylboryl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine In dichloromethane at -78℃;
Stage #2: (1S,4aS,8aS)-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthaleneacetaldehyde In dichloromethane at -78℃; for 2h; Further stages.;
95%
2-buten-4-olide
497-23-4

2-buten-4-olide

phenylboronic acid
98-80-6

phenylboronic acid

(R)-4-phenyl-4,5-dihydrofuran-2(3H)-one
1008-73-7, 68844-05-3, 93601-84-4, 68844-04-2

(R)-4-phenyl-4,5-dihydrofuran-2(3H)-one

Conditions
ConditionsYield
With chlorobis(ethylene)rhodium(I) dimer; (R,R)-(+)-1,4-dimethyl-2,5-diphenylbicyclo[2.2.2]octa-2,5-diene; potassium hydroxide In methanol; dichloromethane at 20℃; for 1h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;95%
With chlorobis(ethylene)rhodium(I) dimer; (1R,4R,7R)-N-(tert-butyl)-7-isopropyl-5-methylbicyclo[2.2.2]octa-2,5-diene-2-carboxamide In water; toluene at 100℃; for 16h; Reagent/catalyst; Inert atmosphere; enantioselective reaction;85%
With chlorobis(ethylene)rhodium(I) dimer; (R)-[6,6'-bis(bis(4-(trifluoromethyl)phenyl)phosphino)-2,2',3,3'-tetrahydro-5,5'-bibenzo[b][1,4]dioxine]; potassium hydroxide In water; toluene at 20℃; for 18h; Hayashi-Miyaura reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;77%
2-buten-4-olide
497-23-4

2-buten-4-olide

1-isoquinolone
491-30-5

1-isoquinolone

(6aR,6bR,9aR,9bS)-6,6a,6b,7-tetrahydrofuro[3',4':3,4]cyclobuta[1,2-c]isoquinoline-5,9(9aH,9bH)-dione

(6aR,6bR,9aR,9bS)-6,6a,6b,7-tetrahydrofuro[3',4':3,4]cyclobuta[1,2-c]isoquinoline-5,9(9aH,9bH)-dione

Conditions
ConditionsYield
With (-)-(1S,5S,7R)-1,5,7-Trimethyl-7-(5',6',7',8'-tetrahydro-1'-oxa-3'-azacyclopenta[b]naphthalene-2'-yl)-3-azabicyclo[3.3.1]nonan-2-one In toluene at -75℃; for 2h; Inert atmosphere; Schlenk technique; Irradiation; enantioselective reaction;95%
With C22H28N2O2 In toluene at -75℃; Inert atmosphere; Irradiation; enantioselective reaction;

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