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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Methoxycarbonylmethylbenzoic acid methyl ester Manufacturer/High quality/Best price/In stock

Cas:52787-14-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Methoxy Carbonyl Methyl-Benzoicacid Methyl Ester supplier in China

Cas:52787-14-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Methoxy Carbonyl Methyl-Benzoicacid Methyl Ester

Cas:52787-14-1

Min.Order:1

Negotiable

Type:Other

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-Methoxycarbonylmethylbenzoic Acid Methyl Ester

Cas:52787-14-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(Methoxycarbonyl)-phenylacetic acid methyl ester

Cas:52787-14-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 52787-14-1 with competitive price

Cas:52787-14-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzeneacetic acid, 4-(methoxycarbonyl)-,methyl ester 52787-14-1

Cas:52787-14-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

methyl 4-(2-methoxy-2-oxoethyl)benzoate CAS52787-14-1

Cas:52787-14-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzeneacetic acid, 4-(methoxycarbonyl)-,methyl ester

Cas:52787-14-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzeneacetic acid, 4-(methoxycarbonyl)-,methyl ester

Cas:52787-14-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Methyl 4-(2-methoxy-2-oxoethyl)benzoateAppearance:None Storage:None Package:according to customers' requirements Application:Pharmaceutical intermediates Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)or a

Methyl 4-(2-methoxy-2-oxoethyl)benzoate

Cas:52787-14-1

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:CLEAR COLOURLESS TO LIGHT YELLOW LIQUID Storage:Well-sealed and put in dry and cool conditions. Protected from direct sunlight or high temperature. Package:as per your request

4-METHOXYCARBONYLMETHYL-BENZOIC ACID METHYL ESTER

Cas:52787-14-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

TIANFU 4-METHOXYCARBONYLMETHYL-BENZOIC ACID METHYL ESTER

Cas:52787-14-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

Pralatrexate 4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

Methyl 4-(2-methoxy-2-oxoethyl)benzoate

Cas:52787-14-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Siwei Development Group Ltd.

Product name: 4-Methoxycarbonylmethylbenzoic Acid Methyl Ester CAS No.:52787-14-1 Molecule Formula:C11H12O4 Molecule Weight:208.21 Purity: 99.0% Package: 25kg/drum Description: White or off-white powder Manufacture Standards:Enterpris

High Quality 4-Methoxycarbonylmethylbenzoic Acid Methyl Ester

Cas:52787-14-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-METHOXYCARBONYLMETHYL-BENZOIC ACID METHYL ESTER

Cas:52787-14-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Benzeneacetic acid, 4-(methoxycarbonyl)-,methyl ester

Cas:52787-14-1

Min.Order:0

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Cas no.52787-14-1 98% Methyl 4-methoxycarbonylphenylacetate

Cas:52787-14-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

4-METHOXYCARBONYLMETHYL-BENZOIC ACID METHYL ESTER

Cas:52787-14-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

4-Methoxycarbonylmethylbenzoic acid methyl ester

Cas:52787-14-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Cas:52787-14-1

Min.Order:0

Negotiable

Type:Other

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

4-Methoxycarbonylmethyl-Benzoic Acid Methyl Ester

Cas:52787-14-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec methyl 4-(2-methoxy-2-oxoethyl)benzoate 100g

Cas:52787-14-1

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methanol
67-56-1

methanol

4-(carboxymethyl)benzoic acid
501-89-3

4-(carboxymethyl)benzoic acid

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide at 50℃; for 4h;95%
With sulfuric acid at 90℃; for 19h;93%
With sulfuric acid a) from 20 deg C to 25 deg C, 3 d, b) reflux, 4.5 h;91%
methanol
67-56-1

methanol

1,1-dibromo-2-(4-methoxycarbonylphenyl)ethene
253684-21-8

1,1-dibromo-2-(4-methoxycarbonylphenyl)ethene

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
With triethylsilane; cyclohexa-1,4-diene; oxygen; cobalt acetylacetonate In nonane at 24℃; under 760.051 Torr; Reagent/catalyst;92%
methanol
67-56-1

methanol

4-(carboxymethyl)benzoic acid
501-89-3

4-(carboxymethyl)benzoic acid

A

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

B

4-(methoxycarbonylmethyl)benzoic acid
87524-66-1

4-(methoxycarbonylmethyl)benzoic acid

Conditions
ConditionsYield
With thionyl chloride at 25 - 27℃; for 7h; Esterification;A 5%
B 90%
With nickel dichloride for 10h; Heating;A 6%
B 85%
With phosphorus pentoxide; copper(II) sulfate; sodium sulfate for 4h; Heating;A 20%
B 70%
methanol
67-56-1

methanol

4-ethynylbenzoic acid methyl ester
3034-86-4

4-ethynylbenzoic acid methyl ester

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
With 4-methylpyridine-1-oxide; chloro(1,5-cyclooctadiene)rhodium(I) dimer; P(p-C6H4F)3 In acetonitrile at 60℃; for 2h; chemoselective reaction;83%
methanol
67-56-1

methanol

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
With hydrogenchloride for 2h; Reflux;81%
With hydrogenchloride at 20℃; for 32h; Heating / reflux;
4-methoxycarbonylphenyl bromide
619-42-1

4-methoxycarbonylphenyl bromide

methyl chloroacetate
96-34-4

methyl chloroacetate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
With manganese; (2,2'-bipyridine)nickel(II) dibromide; trifluoroacetic acid In N,N-dimethyl-formamide at 50℃; for 1h;72%
methanol
67-56-1

methanol

4-Trifluoromethylphenylacetic acid
32857-62-8

4-Trifluoromethylphenylacetic acid

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Stage #1: 4-Trifluoromethylphenylacetic acid With sodium hydride In acetonitrile for 20h; Heating;
Stage #2: methanol; sulfuric acid for 2h; Heating;
51%
nickel (II) chloride hexahydrate

nickel (II) chloride hexahydrate

4-(carboxymethyl)benzoic acid
501-89-3

4-(carboxymethyl)benzoic acid

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
In methanol28.8%
In methanol28.8%
4-Bromophenylacetonitrile
16532-79-9

4-Bromophenylacetonitrile

carbon monoxide
201230-82-2

carbon monoxide

sodium methylate
124-41-4

sodium methylate

A

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

B

(4-bromo-phenyl)-acetic acid methyl ester
41841-16-1

(4-bromo-phenyl)-acetic acid methyl ester

C

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With dicobalt octacarbonyl In methanol at 50℃; Product distribution; Mechanism; Irradiation; other p-halogenobenzyl cyanides, var. time and initial concn.;
triptycene
477-75-8

triptycene

acetyl chloride
75-36-5

acetyl chloride

A

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

B

2,6-diacetyltriptycene
140245-70-1

2,6-diacetyltriptycene

C

2,7-diacetyltriptycene
140245-69-8

2,7-diacetyltriptycene

D

C26H20O3

C26H20O3

Conditions
ConditionsYield
With hydrogenchloride; aluminium trichloride In nitromethane; dichloromethane for 1.66667h; Further byproducts given. Title compound not separated from byproducts;
4-methoxycarbonimidoylmethyl-benzoic acid methyl ester; hydrochloride

4-methoxycarbonimidoylmethyl-benzoic acid methyl ester; hydrochloride

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
With sodium hydrogencarbonate In diethyl ether Yield given;
4-methyl-benzoic acid methyl ester
99-75-2

4-methyl-benzoic acid methyl ester

CO2 anion radical

CO2 anion radical

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 80 percent / N-bromosuccinimide, dibenzoyl-peroxide / CCl4 / 2.5 h / Heating
2: 54 percent / dimethylsulfoxide / 2 h / 40 °C
3: HCl / 8 h / Heating
4: aq. NaHCO3 / diethyl ether
View Scheme
Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 54 percent / dimethylsulfoxide / 2 h / 40 °C
2: HCl / 8 h / Heating
3: aq. NaHCO3 / diethyl ether
View Scheme
Multi-step reaction with 3 steps
1: water; methanol / 5 h / Reflux
2: sodium hydroxide / methanol / 90 °C
3: sulfuric acid / 90 °C
View Scheme
Multi-step reaction with 3 steps
1: tetrabutyl ammonium fluoride / acetonitrile / 12 h / 25 °C
2: sodium hydroxide; water / methanol / 12 h / 90 °C
3: sulfuric acid / 18 h / 90 °C
View Scheme
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HCl / 8 h / Heating
2: aq. NaHCO3 / diethyl ether
View Scheme
With hydrogenchloride In methanol at 20℃; for 32h; Heating / reflux;
Multi-step reaction with 2 steps
1: sodium hydroxide / methanol / 90 °C
2: sulfuric acid / 90 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydroxide; water / methanol / 12 h / 90 °C
2: sulfuric acid / 18 h / 90 °C
View Scheme
p-(chloromethyl)benzoic acid
1642-81-5

p-(chloromethyl)benzoic acid

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 100 percent / aq. NaHCO3 / tetrahydrofuran / 48 h / 20 - 25 °C
2: 90 percent / aq. H2SO4 / 6 h / Heating
3: 91 percent / H2SO4 / a) from 20 deg C to 25 deg C, 3 d, b) reflux, 4.5 h
View Scheme
4-(cyanomethyl)benzoic acid
50685-26-2

4-(cyanomethyl)benzoic acid

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / aq. H2SO4 / 6 h / Heating
2: 91 percent / H2SO4 / a) from 20 deg C to 25 deg C, 3 d, b) reflux, 4.5 h
View Scheme
(4-isopropylphenyl)acetonitrile
4395-87-3

(4-isopropylphenyl)acetonitrile

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous nitric acid
2: sulfuric acid
View Scheme
4-(cyanomethyl)benzonitrile
876-31-3

4-(cyanomethyl)benzonitrile

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous sulfuric acid
2: sulfuric acid
View Scheme
1,3-bis-(diphenylphosphino)propane
6737-42-4

1,3-bis-(diphenylphosphino)propane

(4-Trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester
147283-85-0

(4-Trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
bis(triphenylphosphine)palladium(II)-chloride In methanol; dimethyl sulfoxide
Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: aluminum (III) chloride / carbon disulfide / 12 h / 50 °C
2.1: sodium hydroxide / tetrahydrofuran; water / 1.5 h / 20 °C
3.1: potassium hydroxide / water; 1,4-dioxane / 0.17 h / 0 °C / Cooling with ice
3.2: 3 h / 0 °C / Cooling with ice
4.1: thionyl chloride / N,N-dimethyl-formamide / 4 h / 50 °C
View Scheme
ethyl 4-acetylphenylacetate
1528-42-3

ethyl 4-acetylphenylacetate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium hydroxide / tetrahydrofuran; water / 1.5 h / 20 °C
2.1: potassium hydroxide / water; 1,4-dioxane / 0.17 h / 0 °C / Cooling with ice
2.2: 3 h / 0 °C / Cooling with ice
3.1: thionyl chloride / N,N-dimethyl-formamide / 4 h / 50 °C
View Scheme
sodium 4-acetyl-phenylacetate

sodium 4-acetyl-phenylacetate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: potassium hydroxide / water; 1,4-dioxane / 0.17 h / 0 °C / Cooling with ice
1.2: 3 h / 0 °C / Cooling with ice
2.1: thionyl chloride / N,N-dimethyl-formamide / 4 h / 50 °C
View Scheme
methyl coumalate
6018-41-3

methyl coumalate

Methyl 3,3-dimethoxy-2-methylbutanoate

Methyl 3,3-dimethoxy-2-methylbutanoate

A

dimethyl 4-methylbenzene-1,3-dicarboxylate
23038-61-1

dimethyl 4-methylbenzene-1,3-dicarboxylate

B

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
In toluene at 200℃; for 16h; Overall yield = 76 %; regioselective reaction;
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

[4-(methoxycarbonyl)phenyl]acetic acid
22744-12-3

[4-(methoxycarbonyl)phenyl]acetic acid

Conditions
ConditionsYield
With lithium hydroxide monohydrate; water In tetrahydrofuran; ethanol at 25℃; for 10h;94.4%
With water; potassium carbonate In methanol at 20℃; for 24h;93%
With potassium carbonate In water 100 deg C, 5 min; 35 deg C, 1 h;85%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

1-(hydroxymethyl)-4-(2-hydroxyethyl)benzene
4866-85-7

1-(hydroxymethyl)-4-(2-hydroxyethyl)benzene

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 20 - 30℃; Cooling with ice;90%
With lithium aluminium tetrahydride In diethyl ether Reflux;89%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 2h;
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

allyl bromide
106-95-6

allyl bromide

4-(1-Methoxycarbonyl-but-3-enyl)-benzoic acid methyl ester
153802-44-9

4-(1-Methoxycarbonyl-but-3-enyl)-benzoic acid methyl ester

Conditions
ConditionsYield
With potassium hydride89%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

propargyl bromide
106-96-7

propargyl bromide

α-propargylhomoterephthalic acid dimethyl ester
146464-90-6

α-propargylhomoterephthalic acid dimethyl ester

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate; propargyl bromide In tetrahydrofuran at -10℃; Inert atmosphere;
Stage #2: With lithium hexamethyldisilazane In tetrahydrofuran at -10℃; Temperature; Solvent; Reagent/catalyst;
87%
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With sodium hydride In tetrahydrofuran at 0 - 15℃; Autoclave;
Stage #2: propargyl bromide In tetrahydrofuran at -20 - 10℃; for 5h;
64.5%
With potassium hydride 1.) THF, 0 deg C, 1 h, 2.) THF, a0) o deg C, 30 min, b) RT, 16 h; Yield given. Multistep reaction;
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

1-(2-hydroxyethyl)-4-(3-hydroxypropyl)benzene
143260-83-7

1-(2-hydroxyethyl)-4-(3-hydroxypropyl)benzene

Conditions
ConditionsYield
With lithium aluminium tetrahydride In diethyl ether Reflux;85%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

trimethyl((1-phenylcyclopentyl)peroxy)silane

trimethyl((1-phenylcyclopentyl)peroxy)silane

methyl 4-(1-methoxy-1,7-dioxo-7-phenylheptan-2-yl)benzoate

methyl 4-(1-methoxy-1,7-dioxo-7-phenylheptan-2-yl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With dmap; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: trimethyl((1-phenylcyclopentyl)peroxy)silane In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
80%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

4-(Diethylamino)salicylaldehyde
17754-90-4

4-(Diethylamino)salicylaldehyde

4-(7-Diethylamino-2-oxo-2H-chromen-3-yl)-benzoic acid methyl ester
177093-56-0

4-(7-Diethylamino-2-oxo-2H-chromen-3-yl)-benzoic acid methyl ester

Conditions
ConditionsYield
With piperidine; pyridine at 100℃; for 15h;76%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

aniline
62-53-3

aniline

methyl 4-(2-oxo-2-(phenylamino)ethyl)benzoate
1276030-38-6

methyl 4-(2-oxo-2-(phenylamino)ethyl)benzoate

Conditions
ConditionsYield
With C18H15IMnN3O3; sodium t-butanolate In toluene at 90℃; for 18h; Inert atmosphere; Schlenk technique;76%
With bis(1,5-cyclooctadiene)nickel (0); C45H61N2(1+)*Cl(1-); potassium tert-butylate In toluene at 140℃; for 16h; Reagent/catalyst;65%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

trimethyl((1-phenylcycloheptyl)peroxy)silane

trimethyl((1-phenylcycloheptyl)peroxy)silane

methyl 4-(1-methoxy-1,9-dioxo-9-phenylnonan-2-yl)benzoate

methyl 4-(1-methoxy-1,9-dioxo-9-phenylnonan-2-yl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With dmap; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: trimethyl((1-phenylcycloheptyl)peroxy)silane In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
75%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

trimethyl((1-(p-tolyl)cyclopentyl)peroxy)silane

trimethyl((1-(p-tolyl)cyclopentyl)peroxy)silane

methyl 4-(1-methoxy-1,7-dioxo-7-(4-tolyl)heptan-2-yl)benzoate

methyl 4-(1-methoxy-1,7-dioxo-7-(4-tolyl)heptan-2-yl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With dmap; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: trimethyl((1-(p-tolyl)cyclopentyl)peroxy)silane In N,N-dimethyl-formamide at 50℃; for 1h; Inert atmosphere;
73%
(2-nitroethenyl)benzene
102-96-5

(2-nitroethenyl)benzene

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

C19H19NO6

C19H19NO6

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With 1-((1R,2R)-2-aminocyclohexyl)-3-(3,5-bis(trifluoromethyl)phenyl)thiourea In N,N-dimethyl-formamide at 20℃; for 0.0833333h; Michael Addition;
Stage #2: (2-nitroethenyl)benzene In N,N-dimethyl-formamide at 20℃; for 48h; Michael Addition; diastereoselective reaction;
70%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

aniline
62-53-3

aniline

A

methyl 4-(2-oxo-2-(phenylamino)ethyl)benzoate
1276030-38-6

methyl 4-(2-oxo-2-(phenylamino)ethyl)benzoate

B

4-(2-oxo-2-(phenylamino)ethyl)-N-phenylbenzamide

4-(2-oxo-2-(phenylamino)ethyl)-N-phenylbenzamide

Conditions
ConditionsYield
With C18H15IMnN3O3; sodium t-butanolate In toluene at 120℃; for 18h; Catalytic behavior; Temperature; Inert atmosphere; Schlenk technique;A 66%
B 28%
cyclopentylmethyl Iodide
27935-87-1

cyclopentylmethyl Iodide

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

ammonium chloride

ammonium chloride

4-(2-cyclopentyl-1-methoxycarbonyl-ethyl)-benzoic acid methyl ester

4-(2-cyclopentyl-1-methoxycarbonyl-ethyl)-benzoic acid methyl ester

Conditions
ConditionsYield
In tetrahydrofuran; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone65.7%
In tetrahydrofuran; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone65.7%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

propargyl bromide
106-96-7

propargyl bromide

A

dipropargyl homoterephthalic acid dimethyl ester
1026380-17-5

dipropargyl homoterephthalic acid dimethyl ester

B

α-propargylhomoterephthalic acid dimethyl ester
146464-90-6

α-propargylhomoterephthalic acid dimethyl ester

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; potassium carbonate In N,N-dimethyl acetamide at 25 - 30℃; for 26h; Concentration;A n/a
B 65.6%
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 1h;
Stage #2: propargyl bromide In tetrahydrofuran; mineral oil at 0 - 20℃; for 17h;
With tetra-(n-butyl)ammonium iodide; potassium carbonate In N,N-dimethyl acetamide at 25 - 30℃; Concentration;
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

methyl 4-(1-(dimethylamino)-3-methoxy-3-oxoprop-1-en-2-yl)benzoate

methyl 4-(1-(dimethylamino)-3-methoxy-3-oxoprop-1-en-2-yl)benzoate

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 60℃; for 4h;63%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

1,4-dibenzoyloxy-9,10-anthraquinone
33266-08-9

1,4-dibenzoyloxy-9,10-anthraquinone

C34H20O8

C34H20O8

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 100℃; for 1h; Inert atmosphere;58%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

methyl iodide
74-88-4

methyl iodide

4-(1-methoxycarbonyl-ethyl)-benzoic acid methyl ester
77959-48-9

4-(1-methoxycarbonyl-ethyl)-benzoic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With sodium hydride In tetrahydrofuran at 0℃; for 1h; Metallation;
Stage #2: methyl iodide In tetrahydrofuran at 0 - 20℃; for 16.5h; Methylation; Further stages.;
56%
With potassium hydride 1.) THF, 0 deg C, 30 min, 2.) THF, 0 deg C, 30 min; Yield given. Multistep reaction;
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

trimethyl((1-phenylcyclohexyl)peroxy)silane

trimethyl((1-phenylcyclohexyl)peroxy)silane

methyl 4-(1-methoxy-1,8-dioxo-8-phenyloctan-2-yl)benzoate

methyl 4-(1-methoxy-1,8-dioxo-8-phenyloctan-2-yl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With dmap; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: trimethyl((1-phenylcyclohexyl)peroxy)silane In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
56%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

C20H34O2Si

C20H34O2Si

methyl 4-(1-cyclohexyl-2-methoxy-2-oxoethyl)benzoate

methyl 4-(1-cyclohexyl-2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With dmap; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: C20H34O2Si In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
55%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

(E)-benzalacetone
1896-62-4

(E)-benzalacetone

C21H22O5
1300627-45-5

C21H22O5

Conditions
ConditionsYield
With pyrrolidine In dichloromethane at 20℃; for 48h; Michael addition;54%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

ethyl iodide
75-03-6

ethyl iodide

dimethyl α-ethylhomoterephthalate
88392-91-0

dimethyl α-ethylhomoterephthalate

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With sodium hydride In tetrahydrofuran at 0℃; for 1h; Metallation;
Stage #2: ethyl iodide In tetrahydrofuran at 0 - 20℃; for 17h; Alkylation; Further stages.;
51%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

((1-(4-fluorophenyl)cyclopentyl)peroxy)trimethylsilane

((1-(4-fluorophenyl)cyclopentyl)peroxy)trimethylsilane

methyl 4-(7-(4-fluorophenyl)-1-methoxy-1,7-dioxoheptan-2-yl)benzoate

methyl 4-(7-(4-fluorophenyl)-1-methoxy-1,7-dioxoheptan-2-yl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(2-methoxy-2-oxoethyl)benzoate With dmap; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: ((1-(4-fluorophenyl)cyclopentyl)peroxy)trimethylsilane In N,N-dimethyl-formamide at 50℃; for 1h; Inert atmosphere;
50%
methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

6-bromomethyl-2,4-diaminopteridine hydrobromide
52853-40-4

6-bromomethyl-2,4-diaminopteridine hydrobromide

propargyl bromide
106-96-7

propargyl bromide

A

methyl-4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoate
146464-91-7

methyl-4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoate

B

4-[2-(2,4-diamino-pteridin-6-yl)-1-methoxycarbonyl-ethyl]-benzoic acid methyl ester

4-[2-(2,4-diamino-pteridin-6-yl)-1-methoxycarbonyl-ethyl]-benzoic acid methyl ester

Conditions
ConditionsYield
Multistep reaction;A n/a
B 45%

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