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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Methyl 4-(cyanomethyl)benzoate Manufacturer/High quality/Best price/In stock

Cas:76469-88-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 76469-88-0 with fast shipping

Cas:76469-88-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid,4-(cyanomethyl)-, methyl ester

Cas:76469-88-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:76469-88-0

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Send Pharmaceutical Technology Co., Ltd.

stock,low price,high quality,high purity,good sevice Appearance:76469-88-0 Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,50g,100g,1kg...more Application:R&D Transportation:by land,by

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Methyl4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Cyanomethylbenzoic acid methyl ester

Cas:76469-88-0

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:1 Metric Ton

FOB Price: $28.0

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: Methyl 4-(cyanomethyl)benzoate Synonyms: 4-CYANOMETHYLBENZOIC ACID METHYL ESTER;[p-(Methoxycarbonyl)phenyl]acetonitrile;Methyl p-(CyanoMethyl)benzoate;Methyl α-Cyano-p-toluate;α-Cyano-p-toluic Acid Methyl Ester;95.0%,(

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

76469-88-0 CAS NO.76469-88-0

Cas:76469-88-0

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Manufacturers

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Methyl 4-(cyanomethyl)benzoate cas no. 76469-88-0 98%

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Cyanomethylbenzoic acid methyl ester

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Other

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-(Cyanomethyl)benzoic acid methyl ester

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Methyl 4-(cyanomethyl)benzoate 25g

Cas:76469-88-0

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

high purity Storage:normal temperature Package:DRUM Application:mainly for medical use for R&Dpurpose use only Transportation:AIR,SEA Port:BEIJING,SHANGHAI,TIANJIN,SHENZHEN

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzoic acid,4-(cyanomethyl)-, methyl ester

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Methyl 4-(cyanomethyl)benzoate CAS No.76469-88-0

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Trading Company

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Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

76469-88-0

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Methyl 4-(cyanomethyl)benzoate cas 76469-88-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Methyl 4-(cyanomethyl)benzoate cas 76469-88-0

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:1g Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Methyl 4-(cyanomethyl)benzoate

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Methyl 4-(cyanomethyl)benzoate 76469-88-0

Cas:76469-88-0

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

2-aminoacetonitrile hydrochloride
6011-14-9

2-aminoacetonitrile hydrochloride

4-methoxycarbonylphenylboronic acid
99768-12-4

4-methoxycarbonylphenylboronic acid

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With sodium nitrite In water; 1,2-dichloro-ethane at 100℃; for 24h; Schlenk technique;90%
chloroacetonitrile
107-14-2

chloroacetonitrile

4-methoxycarbonylphenylboronic acid
99768-12-4

4-methoxycarbonylphenylboronic acid

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium carbonate In 1,4-dioxane; water at 60℃; for 12h; Inert atmosphere; Sealed tube;87%
With nickel(II) nitrate hexahydrate; potassium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine; sodium iodide In 1,4-dioxane at 80℃; for 12h; Suzuki Coupling; Inert atmosphere; Sealed tube;80%
4-(methoxycarbonyl)benzyl alcohol
6908-41-4

4-(methoxycarbonyl)benzyl alcohol

potassium cyanide
151-50-8

potassium cyanide

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Stage #1: 4-(methoxycarbonyl)benzyl alcohol With methanesulfonyl chloride; triethylamine In dichloromethane at 0 - 20℃; for 15h;
Stage #2: potassium cyanide With 18-crown-6 ether In acetonitrile at 20℃; for 40h;
86%
Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

potassium cyanide
151-50-8

potassium cyanide

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
In ethanol Substitution; Heating;81%
In ethanol for 24h; Heating;76%
In ethanol; water for 3h; Heating;74%
In ethanol; water for 3.25h; Heating / reflux;
diethyl ether
60-29-7

diethyl ether

p-methyloxycarbonylbenzyl chloride
34040-64-7

p-methyloxycarbonylbenzyl chloride

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
In ethanol; water80%
p-methyloxycarbonylbenzyl chloride
34040-64-7

p-methyloxycarbonylbenzyl chloride

sodium cyanide
143-33-9

sodium cyanide

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 3h;79%
trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Stage #1: trimethylsilyl cyanide With tetrabutyl ammonium fluoride for 1h;
Stage #2: Methyl 4-(bromomethyl)benzoate In acetonitrile at 80℃; for 1h;
68.7%
With tetrabutyl ammonium fluoride In acetonitrile at 25℃; for 12h;
sodium cyanide
773837-37-9

sodium cyanide

Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide In acetonitrile Inert atmosphere; Reflux;65%
In methanol; water for 1.25h; Kolbe nitrile synthesis; Reflux;60%
With N-benzyl-N,N,N-triethylammonium chloride In dichloromethane; water
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

lithium methanolate
865-34-9

lithium methanolate

p-chlorobenzyl cyanide
140-53-4

p-chlorobenzyl cyanide

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With 1,1'-bis-(diphenylphosphino)ferrocene; 5 mol% Pd/C; sodium fluoride In 1,4-dioxane at 150℃; Inert atmosphere;64%
potassium cyanide

potassium cyanide

Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
In methanol; water for 5h; Reflux;58.6%
In methanol; water for 5h; Reflux; Inert atmosphere;
In methanol; water for 5h; Inert atmosphere; Reflux;
Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

sodium cyanide
143-33-9

sodium cyanide

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
In dimethyl sulfoxide at 40℃; for 1.5h;55%
In dimethyl sulfoxide at 40℃; for 1.5h;55%
In dimethyl sulfoxide at 40℃; for 2h;54%
In dimethyl sulfoxide
Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With sodium cyanide
In tetrahydrofuran; water; N,N-dimethyl-formamide6.7 g (76%)
In tetrahydrofuran; water; N,N-dimethyl-formamide6.7 g (76%)
4-(cyanomethyl)benzoic acid
50685-26-2

4-(cyanomethyl)benzoic acid

sodium methylate
124-41-4

sodium methylate

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
In dimethyl sulfoxide
4-Bromophenylacetonitrile
16532-79-9

4-Bromophenylacetonitrile

carbon monoxide
201230-82-2

carbon monoxide

sodium methylate
124-41-4

sodium methylate

A

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

B

(4-bromo-phenyl)-acetic acid methyl ester
41841-16-1

(4-bromo-phenyl)-acetic acid methyl ester

C

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With dicobalt octacarbonyl In methanol at 50℃; Product distribution; Mechanism; Irradiation; other p-halogenobenzyl cyanides, var. time and initial concn.;
4-methyl-benzoic acid methyl ester
99-75-2

4-methyl-benzoic acid methyl ester

Cp2Ti(Cl)CH2Al(CH3)2

Cp2Ti(Cl)CH2Al(CH3)2

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NBS / CCl4
2: dimethylsulfoxide
View Scheme
Multi-step reaction with 2 steps
1: 86 percent / Br2 / benzene / 2 h / Irradiation
2: 74 percent / ethanol; H2O / 3 h / Heating
View Scheme
4-methyl-benzoic acid methyl ester
99-75-2

4-methyl-benzoic acid methyl ester

CO2 anion radical

CO2 anion radical

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent / N-bromosuccinimide, dibenzoyl-peroxide / CCl4 / 2.5 h / Heating
2: 54 percent / dimethylsulfoxide / 2 h / 40 °C
View Scheme
4-bromomethylbenzoic Acid
6232-88-8

4-bromomethylbenzoic Acid

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol. H2SO4
2: NaCN
View Scheme
para-bromotoluene
106-38-7

para-bromotoluene

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: pyridine / 195 °C / Erhitzen des Reaktionsgemisches mit wss. H2SO4 auf 150grad
2: nitrobenzene; bromine
3: methanol. H2SO4
4: NaCN
View Scheme
p-Toluic acid
99-94-5

p-Toluic acid

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: nitrobenzene; bromine
2: methanol. H2SO4
3: NaCN
View Scheme
4-(methoxycarbonyl)benzyl alcohol
6908-41-4

4-(methoxycarbonyl)benzyl alcohol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With triethylamine In dichloromethane; acetonitrile
With triethylamine In dichloromethane; acetonitrile
4-methyl-benzoic acid methyl ester
99-75-2

4-methyl-benzoic acid methyl ester

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Inert atmosphere; Reflux; Irradiation
2: methanol; water / 5 h / Inert atmosphere; Reflux
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 1 h
2: N-benzyl-N,N,N-triethylammonium chloride / dichloromethane; water
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / Inert atmosphere; Reflux
2: tetra-(n-butyl)ammonium iodide / acetonitrile / Inert atmosphere; Reflux
View Scheme
4-Bromophenylacetonitrile
16532-79-9

4-Bromophenylacetonitrile

methyl chloroformate
79-22-1

methyl chloroformate

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Conditions
ConditionsYield
With 2,6-dimethylpyridine; (1,2-dimethoxyethane)dichloronickel(II); tris(triethylsilyl)silane; [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; 4,4'-di-tert-butyl-2,2'-bipyridine In 1,2-dimethoxyethane at 25℃; for 8h; Inert atmosphere; Sealed tube; Irradiation;24 %Spectr.
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

benzaldehyde
100-52-7

benzaldehyde

4-(1-cyano-2-phenylvinyl)benzoic acid methyl ester

4-(1-cyano-2-phenylvinyl)benzoic acid methyl ester

Conditions
ConditionsYield
With L-proline In dimethyl sulfoxide at 25℃; for 71h;99%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

methyl 4-(2-oxo-2H-chromen-3-yl)benzoate

methyl 4-(2-oxo-2H-chromen-3-yl)benzoate

Conditions
ConditionsYield
With potassium fluoride at 80℃; for 5.5h; Inert atmosphere;99%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl 4-(2-amino-2-(hydroxyimino)ethyl)benzoate

methyl 4-(2-amino-2-(hydroxyimino)ethyl)benzoate

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium hydrogencarbonate In ethanol at 65℃; for 18h;99%
With hydroxylamine hydrochloride; sodium hydrogencarbonate In ethanol at 65℃; for 18h;99%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

dimethyl sulfate
77-78-1

dimethyl sulfate

methyl 4-(1-cyano-1-methylethyl)-benzoate

methyl 4-(1-cyano-1-methylethyl)-benzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(cyanomethyl)benzoate With tetrabutylammomium bromide; sodium hydroxide In water at 20℃; Large scale reaction;
Stage #2: dimethyl sulfate In water at 0 - 3℃; for 4h;
96%
C-phenyl-N-methylnitrone
3376-23-6, 7372-59-0, 59862-60-1

C-phenyl-N-methylnitrone

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

Triethylsilyl trifluoromethanesulfonate
79271-56-0

Triethylsilyl trifluoromethanesulfonate

methyl 4-(1-cyano-2-(methyl((triethylsilyl)oxy)amino)-2-phenylethyl)benzoate

methyl 4-(1-cyano-2-(methyl((triethylsilyl)oxy)amino)-2-phenylethyl)benzoate

Conditions
ConditionsYield
With triethylamine In 1,2-dichloro-ethane at -30℃; for 0.5h; Inert atmosphere;96%
2-formyl-5,10,15,20-tetrakis-(3,5-dimethylphenyl)porphyrin

2-formyl-5,10,15,20-tetrakis-(3,5-dimethylphenyl)porphyrin

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

C63H53N5O2

C63H53N5O2

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 23℃; for 1h; Knoevenagel Condensation; Inert atmosphere;93%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

4-(cyanomethyl)benzoic acid
50685-26-2

4-(cyanomethyl)benzoic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol at 80℃; for 3h;92.2%
With sodium hydroxide In methanol for 3h; Reflux;92.2%
Stage #1: methyl 4-(cyanomethyl)benzoate With water; lithium hydroxide In tetrahydrofuran at 20℃; for 16h;
Stage #2: With hydrogenchloride In water
86%
Stage #1: methyl 4-(cyanomethyl)benzoate With water; lithium hydroxide In tetrahydrofuran at 20℃; for 16h;
Stage #2: With hydrogenchloride In water
86%
With potassium hydroxide In water at 0 - 20℃; for 2h;26%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

4-(2-amino-ethyl)-benzoic acid methyl ester
77265-67-9

4-(2-amino-ethyl)-benzoic acid methyl ester

Conditions
ConditionsYield
90%
With ammonia; hydrogen In methanol at 55℃;66%
With hydrogen; palladium on activated charcoal
With borane-THF In tetrahydrofuran for 15h;
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl 4-[2-(tert-butoxycarbonylamino)ethyl]benzoate
177736-04-8

methyl 4-[2-(tert-butoxycarbonylamino)ethyl]benzoate

Conditions
ConditionsYield
With triethylamine; platinum (IV) oxide In methanol; dichloromethane; chloroform88%
With triethylamine; platinum (IV) oxide In methanol; dichloromethane; chloroform88%
Stage #1: methyl 4-(cyanomethyl)benzoate With hydrogen; platinum(IV) oxide In methanol; chloroform at 20℃; for 3h;
Stage #2: di-tert-butyl dicarbonate With triethylamine In dichloromethane at 0 - 20℃; for 13h;
88%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl 4-(1H-tetrazol-5-ylmethyl)benzoate
1246251-02-4

methyl 4-(1H-tetrazol-5-ylmethyl)benzoate

Conditions
ConditionsYield
With sodium azide; N,N-diethylethanamine hydrochloride In toluene at 100℃; for 24h; Inert atmosphere;88%
With sodium azide; triethylamine hydrochloride In toluene at 100℃; for 24h; Inert atmosphere;88%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

4-(carboxymethyl)benzoic acid
501-89-3

4-(carboxymethyl)benzoic acid

Conditions
ConditionsYield
With sulfuric acid In water at 5℃;87%
With sodium hydroxide In methanol at 90℃;70%
With sodium hydroxide
With sulfuric acid; water at 125℃;
With water; sodium hydroxide In methanol at 90℃; for 12h;
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

C41H43N3O3S2

C41H43N3O3S2

C51H50N4O4S2

C51H50N4O4S2

Conditions
ConditionsYield
With piperidine In tetrahydrofuran; acetonitrile Inert atmosphere; Reflux;87%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

4-(2-aminoethyl)-benzyl alcohol
64353-30-6

4-(2-aminoethyl)-benzyl alcohol

Conditions
ConditionsYield
With diborane In tetrahydrofuran for 10h; Heating;85%
Stage #1: methyl 4-(cyanomethyl)benzoate With aluminum (III) chloride; lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at 20℃; Inert atmosphere;
Stage #2: With sulfuric acid; water In tetrahydrofuran; diethyl ether
78%
With aluminum (III) chloride; lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at 20℃; Inert atmosphere;78%
triethylsilane
617-86-7

triethylsilane

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

2-(4’-methylcarboxylate)-N,N-bis(triethylsilyl)phenethylamine

2-(4’-methylcarboxylate)-N,N-bis(triethylsilyl)phenethylamine

Conditions
ConditionsYield
With tris(pentafluorophenyl)borate In dichloromethane at 20℃; for 8h;84%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

12-formyl-5,10,15,20-tetraphenyl-21H,23H-porphine

12-formyl-5,10,15,20-tetraphenyl-21H,23H-porphine

C55H37N5O2

C55H37N5O2

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 23℃; for 0.5h; Knoevenagel Condensation; Inert atmosphere;84%
10-ethyl-10H-phenothiazine-3-carbaldehyde
18413-61-1

10-ethyl-10H-phenothiazine-3-carbaldehyde

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl (Z)-4-(1-cyano-2-(10-ethyl-10H-phenothiazin-3-yl)vinyl)benzoate

methyl (Z)-4-(1-cyano-2-(10-ethyl-10H-phenothiazin-3-yl)vinyl)benzoate

Conditions
ConditionsYield
Stage #1: 10-ethyl-10H-phenothiazine-3-carbaldehyde; methyl 4-(cyanomethyl)benzoate In ethanol for 0.166667h; Reflux;
Stage #2: With pyrrolidine In ethanol for 2h; Reflux;
84%
4-methylphenyl isocyanide
7175-47-5

4-methylphenyl isocyanide

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl (Z)-4-(1-cyano-2-(p-tolylamino)vinyl)benzoate

methyl (Z)-4-(1-cyano-2-(p-tolylamino)vinyl)benzoate

Conditions
ConditionsYield
With copper(l) iodide; potassium tert-butylate In 1,2-dimethoxyethane at 55 - 60℃; for 16h; Inert atmosphere;83%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

C14H15ClN2O4

C14H15ClN2O4

methyl 4-((1-(benzyloxy)-3-(ethoxymethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)(cyano)methyl)benzoate

methyl 4-((1-(benzyloxy)-3-(ethoxymethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)(cyano)methyl)benzoate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;83%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl iodide
74-88-4

methyl iodide

4-(1-cyano-1-methylethyl)benzoic acid
129488-74-0

4-(1-cyano-1-methylethyl)benzoic acid

Conditions
ConditionsYield
Stage #1: methyl 4-(cyanomethyl)benzoate With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: methyl iodide In tetrahydrofuran at 0 - 25℃; for 12h;
Stage #3: With hydrogenchloride In water
83%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

4-(2-aminoethyl)-benzoic acid methyl ester-hydrochloride
56161-89-8

4-(2-aminoethyl)-benzoic acid methyl ester-hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; palladium on activated charcoal In ethanol at 20℃; for 48h; Catalytic hydrogenation;81%
With hydrogenchloride; hydrogen; 5%-palladium/activated carbon In tetrahydrofuran; methanol for 2h;57.87%
methanol
67-56-1

methanol

methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

methyl 4-(2-methoxy-2-oxoethyl)benzoate
52787-14-1

methyl 4-(2-methoxy-2-oxoethyl)benzoate

Conditions
ConditionsYield
With hydrogenchloride for 2h; Reflux;81%
With hydrogenchloride at 20℃; for 32h; Heating / reflux;
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

10-ethyl-10H-phenothiazine-3,7-dicarboxaldehyde
204977-17-3

10-ethyl-10H-phenothiazine-3,7-dicarboxaldehyde

dimethyl 4,4′-((1Z,1′Z)-(10-ethyl-10H-phenothiazine-3,7-diyl)bis1-cyanoethene-2,1-diyl)dibenzoate

dimethyl 4,4′-((1Z,1′Z)-(10-ethyl-10H-phenothiazine-3,7-diyl)bis1-cyanoethene-2,1-diyl)dibenzoate

Conditions
ConditionsYield
Stage #1: methyl 4-(cyanomethyl)benzoate; 10-ethyl-10H-phenothiazine-3,7-dicarboxaldehyde In ethanol for 0.166667h; Reflux;
Stage #2: With pyrrolidine In ethanol for 2h; Reflux;
81%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

(E)-benzalacetone
1896-62-4

(E)-benzalacetone

C20H19NO3
1300627-55-7

C20H19NO3

Conditions
ConditionsYield
With pyrrolidine In dichloromethane at 20℃; for 40h; Michael addition;77%
methyl 4-(cyanomethyl)benzoate
76469-88-0

methyl 4-(cyanomethyl)benzoate

C15H17NO3

C15H17NO3

C25H24N2O4

C25H24N2O4

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 60℃; for 6h; pH=Ca. 10;75%

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