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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Bromo-6-Methylpyridine supplier in China

Cas:5315-25-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for 2-Bromo-6-methylpyridine Cas 5315-25-3 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Light yellow liquid Storage:N/A Package:25kg/drum,200kg/drum

Factory high quality 2-Bromo-6-methylpyridine Cas 5315-25-3 with reasonable price

Cas:5315-25-3

Min.Order:1 Kilogram

FOB Price: $164.0 / 194.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Bromo-6-Methylpyridine

Cas:5315-25-3

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

6-Bromo-α-picoline

Cas:5315-25-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 2-bromo-6-methylpyridine CAS No. 5315-25-3

2-Br-6-Me-pyridine

Cas:5315-25-3

Min.Order:1 Metric Ton

FOB Price: $12.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Best qualityCAS 5315-25-3 with high-quality service

Cas:5315-25-3

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 2-Bromo-6-methylpyridine Synonyms: Bromomethylpyridine CAS: 5315-25-3 MF: C6H6BrN Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Agrochemical Intermediates, Dyestuff Inter

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1.Good capacity; 2.Safe deliver 3. High quality with best price Appearance:White Powder Storage:Dry and cool place Package:100g/ bag, 2 kg/ bag, 25kg/ carton or as required Application:For Pharmaceutical Intermediates Transportation:By DHL, TNT

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pyridine,2-bromo-6-methyl- 5315-25-3

Cas:5315-25-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2-Bromo-6-methylpyridine CAS:5315-25-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

2-Bromo-6-methylpyridine CAS:5315-25-3

Cas:5315-25-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pyridine,2-bromo-6-methyl-

Cas:5315-25-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biological Technology Co., Ltd. is specialize in the production of chemical raw materials and reagents,located in Shijiazhuang, Hebei Province. In recent decades, under the efforts of all staff, in Shandong, Henan, Guangdong and many othe

2-Bromo-6-methylpyridine CAS 5315-25-3

Cas:5315-25-3

Min.Order:1 Kilogram

FOB Price: $20.0 / 40.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pyridine,2-bromo-6-methyl-

Cas:5315-25-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 5315-25-3 ,2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Bromo-6-Methylpyridine

Cas:5315-25-3

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2-bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

cas:5315-25-3

Cas:5315-25-3

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:light yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pesticide int

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on

good 2-Bromo-6-methyl-pyridine

Cas:5315-25-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

2-Bromo-6-methylpyridine Chemical Properties Boiling point 102-103 °C/20 mmHg (lit.) density 1.512 g/mL at 25 °C (lit.) refractive index n20/D 1.562(lit.) Fp 207 °F pka 1.51±0.10(Predicted) form Liquid color

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Bromo-6-methylpyridine

Cas:5315-25-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Synthetic route

2-Amino-6-methylpyridine
1824-81-3

2-Amino-6-methylpyridine

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
Stage #1: 2-Amino-6-methylpyridine With hydrogen bromide; bromine at -10 - -5℃; for 1.5h;
Stage #2: With sodium nitrite In water at -10 - -5℃; for 1.5h;
Stage #3: With sodium hydroxide In water at -10℃;
95%
Stage #1: 2-Amino-6-methylpyridine With hydrogen bromide at 60 - 62℃; for 1h;
Stage #2: With bromine at -5 - -3℃; for 3h;
Stage #3: With sodium nitrite In water for 3h; Temperature;
93.1%
Stage #1: 2-Amino-6-methylpyridine With bromine at -20℃; for 1.5h;
Stage #2: With sodium nitrite at -20 - 15℃;
Stage #3: With sodium hydroxide at -10 - 20℃; Further stages.;
90%
2,6-Dibromopyridine
626-05-1

2,6-Dibromopyridine

methyllithium
917-54-4

methyllithium

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
In diethyl ether at -25 - 0℃; for 4h;59%
6-chloro-2-picoline
18368-63-3

6-chloro-2-picoline

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
With trimethylsilyl bromide In various solvent(s) for 100h; Heating;47%
6-hydroxy-2-methylpyridine
3279-76-3

6-hydroxy-2-methylpyridine

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
With phosphorus(V) oxybromide
6-hydroxy-2-methylpyridine
3279-76-3

6-hydroxy-2-methylpyridine

A

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

B

2,3,5-tribromo-6-methyl-pyridine
3430-15-7

2,3,5-tribromo-6-methyl-pyridine

Conditions
ConditionsYield
With phosphorus pentabromide at 160℃;
6-hydroxy-2-methylpyridine
3279-76-3

6-hydroxy-2-methylpyridine

phosphorus yl bromide

phosphorus yl bromide

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
at 160℃;
2-Amino-6-methylpyridine
1824-81-3

2-Amino-6-methylpyridine

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

aqueous NaNO2

aqueous NaNO2

A

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

B

3,5-dibromo-2-hydroxy-6-methylpyridine
500587-45-1

3,5-dibromo-2-hydroxy-6-methylpyridine

6-hydroxy-2-methylpyridine
3279-76-3

6-hydroxy-2-methylpyridine

phosphorus pentabromide
7789-69-7

phosphorus pentabromide

A

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

B

2,3(?),5(?)-tribromo-6-methyl-pyridine(mp: 75-76 degree )

2,3(?),5(?)-tribromo-6-methyl-pyridine(mp: 75-76 degree )

Conditions
ConditionsYield
at 160℃;
α-picoline
109-06-8

α-picoline

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaNH2; xylene
2: aqueous hydrobromic acid / Behandeln mit Brom und mit wss. Natriumnitrit-Loesung
View Scheme
2,6-Dibromopyridine
626-05-1

2,6-Dibromopyridine

methyl iodide
74-88-4

methyl iodide

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
Stage #1: 2,6-Dibromopyridine With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 1.52778E-05h;
Stage #2: methyl iodide In tetrahydrofuran; hexane at 0℃; for 0.0025h;
94 %Chromat.
Stage #1: 2,6-Dibromopyridine With n-butyllithium In hexane at 0℃; for 1.52778E-05h;
Stage #2: methyl iodide In tetrahydrofuran; hexane at 0℃; for 0.0025h;
94 %Chromat.
2,6-Dibromopyridine
626-05-1

2,6-Dibromopyridine

dimethyl sulfate
77-78-1

dimethyl sulfate

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
Stage #1: 2,6-Dibromopyridine With n-butyllithium In diethyl ether
Stage #2: dimethyl sulfate at -78 - 20℃; for 16h;
6-methyl-2-pyridinecarboxylic acid
934-60-1

6-methyl-2-pyridinecarboxylic acid

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Conditions
ConditionsYield
With tert-butylhypochlorite; dichloromethane; oxygen; sodium hydrogencarbonate at 70℃; for 30h; Green chemistry;35 %Spectr.
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

1-Heptyne
628-71-7

1-Heptyne

2-(hept-1-yn-1-yl)-6-methylpyridine
334026-55-0

2-(hept-1-yn-1-yl)-6-methylpyridine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride at 60℃; for 1.5h;100%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 60℃; Inert atmosphere;100%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

phenylboronic acid
98-80-6

phenylboronic acid

6-methyl-2-phenylpyridine
46181-30-0

6-methyl-2-phenylpyridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In ethanol; water; toluene for 18h; Inert atmosphere; Reflux;100%
With potassium phosphate; palladium diacetate In ethylene glycol at 80℃; Inert atmosphere;99%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol at 100℃; for 15h; Inert atmosphere;99%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

tributyltin chloride
1461-22-9

tributyltin chloride

2-methyl-6-(tributylstannyl)pyridine
259807-95-9

2-methyl-6-(tributylstannyl)pyridine

Conditions
ConditionsYield
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 3h; Schlenk technique; Inert atmosphere;
Stage #2: tributyltin chloride In tetrahydrofuran; hexane at 20℃; Schlenk technique; Inert atmosphere;
100%
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1.5h; Inert atmosphere;
Stage #2: tributyltin chloride In tetrahydrofuran; hexane at 20℃; Inert atmosphere;
100%
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium In tetrahydrofuran at -78℃; for 3h;
Stage #2: tributyltin chloride In tetrahydrofuran at 20℃;
96.75%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

bis[(2-bromo-6-methylpyridinium)hexafluorosilicate] monohydrate

bis[(2-bromo-6-methylpyridinium)hexafluorosilicate] monohydrate

Conditions
ConditionsYield
With fluorosilicic acid; water In methanol at 20℃;100%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

Diethyl carbonate
105-58-8

Diethyl carbonate

(6-bromo-pyridin-2-yl)-acetic acid ethyl ester
955369-63-8

(6-bromo-pyridin-2-yl)-acetic acid ethyl ester

Conditions
ConditionsYield
With n-butyllithium; diisopropylamine In tetrahydrofuran at -60 - -40℃; for 16h;100%
Stage #1: 2-bromo-6-methylpyridine With lithium diisopropyl amide In tetrahydrofuran at -70℃; for 0.5h;
Stage #2: Diethyl carbonate In tetrahydrofuran at -70 - 20℃; for 4h;
77%
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: Diethyl carbonate In tetrahydrofuran; hexane at -78 - 20℃;
55%
Stage #1: 2-bromo-6-methylpyridine With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: Diethyl carbonate In tetrahydrofuran at -78 - 20℃; Inert atmosphere;
53%
Stage #1: 2-bromo-6-methylpyridine With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: Diethyl carbonate In tetrahydrofuran at -78℃; Inert atmosphere;
35%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

3,3-dimethyl-butan-2-one
75-97-8

3,3-dimethyl-butan-2-one

1-(6-bromopyridin-2-yl)-2,3,3-trimethylbutan-2-ol

1-(6-bromopyridin-2-yl)-2,3,3-trimethylbutan-2-ol

Conditions
ConditionsYield
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78 - 0℃; for 0.5h;
Stage #2: 3,3-dimethyl-butan-2-one In tetrahydrofuran; hexane at -78 - 20℃; for 0.5h;
100%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

6,6'-dimethyl-2,2'-bipyridine
4411-80-7

6,6'-dimethyl-2,2'-bipyridine

Conditions
ConditionsYield
With Ni(acetylacetate)2; 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-diaza-2,5-cyclo-hexadiene In toluene at 80℃; for 18h;99%
nickel dibromide In N,N-dimethyl-formamide at 20℃; Electrochemical reaction; constant current intensity 200 mA;98%
Stage #1: 2-bromo-6-methylpyridine With lithium chloride; nickel dichloride; zinc In N,N-dimethyl-formamide at 50℃; for 0.0833333h;
Stage #2: With iodine; acetic acid In N,N-dimethyl-formamide at 50℃; for 0.333333h;
Stage #3: 2-bromo-6-methylpyridine In N,N-dimethyl-formamide at 80℃; for 24h;
98%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

4-(diphenylamino)phenyl boronic acid
201802-67-7

4-(diphenylamino)phenyl boronic acid

N,N-diphenyl-4-(6-methylpyridinyl-2-yl)aniline
144034-56-0

N,N-diphenyl-4-(6-methylpyridinyl-2-yl)aniline

Conditions
ConditionsYield
With potassium phosphate tribasic heptahydrate; palladium diacetate In water; isopropyl alcohol at 80℃; for 0.133333h; Suzuki reaction;99%
With palladium diacetate; potassium carbonate In ethanol; water at 80℃; for 0.0666667h; Suzuki Coupling;98%
With palladium diacetate; potassium carbonate In ethanol; water at 80℃; Suzuki Coupling;
With palladium diacetate; potassium carbonate In ethanol; water at 80℃; for 1h; Suzuki Coupling;
4-(carbazol-9-yl)phenylboronic acid
419536-33-7

4-(carbazol-9-yl)phenylboronic acid

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

9-(4-(6-methylpyridin-2-yl)phenyl)-9H-carbazole
1380225-68-2

9-(4-(6-methylpyridin-2-yl)phenyl)-9H-carbazole

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate In ethanol; water at 80℃; for 0.0833333h; Suzuki Coupling;99%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

4-Chlorophenylboronic acid
1679-18-1

4-Chlorophenylboronic acid

2-(4-chlorophenyl)-6-methylpyridine
61704-26-5

2-(4-chlorophenyl)-6-methylpyridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 70 - 90℃; for 18h; Inert atmosphere;99%
With potassium phosphate; palladium diacetate In ethylene glycol at 80℃; Inert atmosphere;87%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

3-phenylsydnone
508191-77-3

3-phenylsydnone

4-(6-methyl-2-pyridyl)-N-phenylsydnone

4-(6-methyl-2-pyridyl)-N-phenylsydnone

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; XPhos In N,N-dimethyl-formamide at 80 - 120℃; for 16h; Inert atmosphere;99%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

Triisopropyl borate
5419-55-6

Triisopropyl borate

C15H27BNO3(1-)*Li(1+)

C15H27BNO3(1-)*Li(1+)

Conditions
ConditionsYield
at -78℃;99%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

6,6'-dimethyl-2,2'-thiodipyridine
85060-42-0

6,6'-dimethyl-2,2'-thiodipyridine

Conditions
ConditionsYield
With thiourea In ethanol at 78℃; for 36h; Inert atmosphere;99%
With thiourea In ethanol for 36h; Inert atmosphere; Schlenk technique; Reflux;93%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

tributyl(thien-2-yl)stannane
54663-78-4

tributyl(thien-2-yl)stannane

2-(thiophen-2'-yl)-6-methylpyridine
56421-69-3

2-(thiophen-2'-yl)-6-methylpyridine

Conditions
ConditionsYield
With copper(l) iodide; tri-tert-butyl phosphine; cesium fluoride; palladium dichloride In N,N-dimethyl-formamide at 45℃; for 15h; Stille reaction;98%
With cesium fluoride; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane at 100℃; for 36h; Stille coupling;96%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

trimethyltin(IV)chloride
1066-45-1

trimethyltin(IV)chloride

2-methyl-6-(trimethylstannyl)pyridine
126225-57-8

2-methyl-6-(trimethylstannyl)pyridine

Conditions
ConditionsYield
With n-BuLi In tetrahydrofuran under N2 atm. soln. 2-bromo-6-methylpyridine in THF was cooled to -78°C, treated dropwise with soln. n-BuLi in hexane, stirred for 30 min, soln. Me3SnCl in THF was added and stirred for 1 h, warmed to room temp.; react. mixt. was quenched with aq. NH4Cl, extd. with Et2O, dried over Na2SO4, solvent was removed in vacuo; elem. anal.;97%
With BuLi In tetrahydrofuran dropwise addn. of pyridine in THF to BuLi in THF at -78°C, stirred for 1 h, addn. of Me3SnCl in THF at -78°C, allowed to warm to room temp.; removal of solvent under reduced pressure, addn. of methylcyclohexane, filtered off, removal of solvent, distn.;58%
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium In diethyl ether; hexane at -78℃; for 1.16667h; Inert atmosphere;
Stage #2: trimethyltin(IV)chloride In tetrahydrofuran; diethyl ether; hexane at -78 - 20℃; for 3h;
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium In diethyl ether; hexane at -78℃; for 1.16667h; Inert atmosphere;
Stage #2: trimethyltin(IV)chloride In tetrahydrofuran; diethyl ether; hexane at -78 - 20℃; for 3h; Inert atmosphere;
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium In tetrahydrofuran; hexane at -65℃; for 3.5h; Irradiation; Inert atmosphere; Schlenk technique;
Stage #2: trimethyltin(IV)chloride In tetrahydrofuran at -65 - 20℃; for 1h; Inert atmosphere; Schlenk technique;
NH-pyrazole
288-13-1

NH-pyrazole

2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

2-methyl-6-(1H-pyrazole-1-yl)pyridine
76211-97-7

2-methyl-6-(1H-pyrazole-1-yl)pyridine

Conditions
ConditionsYield
With copper(l) iodide; caesium carbonate In dimethyl sulfoxide at 120℃; for 24h; Inert atmosphere;97%
With potassium tert-butylate In dimethyl sulfoxide at 120℃; Inert atmosphere; Schlenk technique;90%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

methyl 2-[(tert-butoxycarbonyl)amino]acrylate
55477-80-0

methyl 2-[(tert-butoxycarbonyl)amino]acrylate

C15H22N2O4

C15H22N2O4

Conditions
ConditionsYield
With (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate In water; dimethyl sulfoxide at 23℃; for 16h; Irradiation;97%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

N-Benzylidenemethylamine
622-29-7

N-Benzylidenemethylamine

2-(6-bromopyridin-2-yl)-N-methyl-1-phenylethan-1-amine

2-(6-bromopyridin-2-yl)-N-methyl-1-phenylethan-1-amine

Conditions
ConditionsYield
Stage #1: 2-bromo-6-methylpyridine With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78 - 0℃; for 0.5h;
Stage #2: N-Benzylidenemethylamine In tetrahydrofuran; hexane at -78 - 20℃; for 0.5h;
97%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

2-ethynylpyridine
1945-84-2

2-ethynylpyridine

2-Methyl-6-pyridin-2-ylethynyl-pyridine
824389-35-7

2-Methyl-6-pyridin-2-ylethynyl-pyridine

Conditions
ConditionsYield
With copper(l) iodide; diisopropylamine; tetrakis(triphenylphosphine) palladium(0) In toluene at 20℃; for 12h; Sonogashira coupling;96%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

o-fluorophenylboronic acid
1993-03-9

o-fluorophenylboronic acid

2-(2-fluorophenyl)-6-methylpyridine

2-(2-fluorophenyl)-6-methylpyridine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In 1,2-dimethoxyethane; water at 80℃; Suzuki-Miyaura coupling; Inert atmosphere;96%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

7-Azaindole
271-63-6

7-Azaindole

1-(6-methylpyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine

1-(6-methylpyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With copper(I) oxide; potassium phosphate; N1,N2-bis(furan-2-ylmethyl)oxalamide In dimethyl sulfoxide at 120℃; for 36h;96%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

butan-1-ol
71-36-3

butan-1-ol

6-butoxy-α-picoline
134319-26-9

6-butoxy-α-picoline

Conditions
ConditionsYield
With copper(l) iodide; N1, N2-diphenethyloxalamide; sodium t-butanolate In 1,4-dioxane for 24h; Schlenk technique; Inert atmosphere; Molecular sieve; Heating;96%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

tert-butyl-4-(6-methylpyridin-2-yl)piperazine-1-carboxylate
127188-33-4

tert-butyl-4-(6-methylpyridin-2-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 70℃; for 1.5h;95%
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 70℃; for 1.5h;95%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

N-(2,4,6-trimethylphenyl)imidazole
25364-44-7

N-(2,4,6-trimethylphenyl)imidazole

1-mesityl-3-(6-methyl-2-pyridyl)imidazolium bromide
1297842-16-0

1-mesityl-3-(6-methyl-2-pyridyl)imidazolium bromide

Conditions
ConditionsYield
at 150℃; Inert atmosphere;95%
at 150℃; for 72h;45%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

2-Methoxyphenylboronic acid
5720-06-9

2-Methoxyphenylboronic acid

2-(2-methoxyphenyl)-6-methylpyridine
113577-68-7

2-(2-methoxyphenyl)-6-methylpyridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In ethanol; water at 80℃; Suzuki-Miyaura Coupling;95%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate In 1,4-dioxane; water at 90℃; Inert atmosphere;71%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

diphenyl (prop-2-yn-1-yl)phosphine oxide
104856-81-7

diphenyl (prop-2-yn-1-yl)phosphine oxide

((1-(6-methylpyridin-2-yl)-1H-1,2,3-triazol-4-yl)methyl)diphenylphosphine oxide

((1-(6-methylpyridin-2-yl)-1H-1,2,3-triazol-4-yl)methyl)diphenylphosphine oxide

Conditions
ConditionsYield
With sodium azide; bromotris(triphenylphosphine)copper(I) In water; dimethyl sulfoxide at 110℃; under 760.051 Torr; for 0.183333h; Huisgen Cycloaddition; Microwave irradiation; Green chemistry; regioselective reaction;95%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

(E)-2-(4-methoxyphenyl)vinylboronic acid
72316-18-8

(E)-2-(4-methoxyphenyl)vinylboronic acid

C15H15NO
858803-73-3

C15H15NO

Conditions
ConditionsYield
With potassium phosphate In ethanol; water at 80℃; for 6h; Suzuki-Miyaura Coupling; Inert atmosphere;95%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

2-bromo-6-methylpyridine N-oxide
91668-84-7

2-bromo-6-methylpyridine N-oxide

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid at 90℃; for 24h;94%
With dihydrogen peroxide; acetic acid at 90℃; for 24h;94%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane90%
2-bromo-6-methylpyridine
5315-25-3

2-bromo-6-methylpyridine

tris(6-methylpyridin-2-yl)amine
623900-59-4

tris(6-methylpyridin-2-yl)amine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; lithium amide In N,N-dimethyl-formamide at 130℃; for 24h; Inert atmosphere; chemoselective reaction;94%

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