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Nanjing Fred Technology Co.,Ltd.

Taizhou FremChem Co. Ltd. is a high-tech enterprise located in China Medical City specializing in R&D, manufacturing, sales of new APIS, pharmaceutical intermediates and fine chemicals. All of our company is committed to provide high quality chemical

7-Azaindole

Cas:271-63-6

Min.Order:10 Kilogram

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for t

High quality 7-Azaindole supplier in China

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 7-Azaindole supplier in China

Cas:271-63-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality 7-Azaindole CAS 271-63-6 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, F

High quality 7-Azaindole CAS 271-63-6 with factory price

Cas:271-63-6

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Jinan Finer Chemical Co., Ltd

Product description: Product name 7-Azaindole CAS number 271-63-6 Assay ≥98% Appearance Off-white powder Capacity 200mt/year Application Organic synthesis More info

7-Azaindole

Cas:271-63-6

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

7-Azaindole

Cas:271-63-6

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 7-Azaindole

Cas:271-63-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 271-63-6 7-Azaindole

Cas:271-63-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

7-Azaindole

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

7-Azaindole

Cas:271-63-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: 7-Azaindole Synonyms: 1,7-Diaza-1H-indene;7-Aza-7H-indole;7-Dideazapurine;7-Azaindole, 98% 5GR;NSC 67063;NSC 77951;7-AZAINDOLE FOR SYNTHESIS 1 G;7-Azaindole SynonyMs 1H-Pyrrolo[2,3-b]pyridine CAS: 271-63-6 MF:

271-63-6 7-Azaindole

Cas:271-63-6

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

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Leader Biochemical Group

About Product Details 7-Azaindole Basic information Product Name: 7-Azaindole Synonyms: 1,7-Diaza-1H-indene;7-Aza-7H-indole;7-Aza-1-pyrindine;7H-Pyrrolo[2,3-b]pyridine;Pyrrolo(2,3

Highest Purity Quality Supply 99% 7-Azaindole CAS 271-63-6

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

7-Azaindole CAS 271-63-6

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 271-63-6 with fast shipping

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powder 2. Fact

7-AzaindoleCAS271-63-6

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 1H-Pyrrolo[2,3-b]pyridine Molecular Formula:C7H6N2 Molecular Weight:118.14 CAS No.:271-63-6 Appearance:Similar White Or Slight Yellow Solid Appearance:Similar White Or Slight Yellow Solid Storage:Store in cool and dry place, away from su

1H-Pyrrolo[2,3-b]pyridine

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

7-Azaindole 271-63-6 Pharmaceutical Raw materials

Cas:271-63-6

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

7-Azaindole 271-63-6

Cas:271-63-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

7-Azaindole

Cas:271-63-6

Min.Order:1 Kilogram

FOB Price: $85.0 / 100.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

7-Azaindole CAS:271-63-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

7-Azaindole CAS:271-63-6

Cas:271-63-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

7-Azaindole

Cas:271-63-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

High quality 7-Azaindole supplier in China CAS NO.271-63-6

Cas:271-63-6

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:271-63-6

Cas:271-63-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

7-Azaindole

Cas:271-63-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

7-Azaindole

Cas:271-63-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

7-Azaindole CAS NO.271-63-6

Cas:271-63-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

7-Azaindole

Cas:271-63-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

7-Azaindole

Cas:271-63-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

7-Azaindole

Cas:271-63-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1H-pyrrolo[2,3-b]pyridine

Cas:271-63-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1-(tert-butoxycarbonyl)-1H-pyrrolo<2,3-b>pyridine
138343-77-8

1-(tert-butoxycarbonyl)-1H-pyrrolo<2,3-b>pyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With sodium carbonate In 1,2-dimethoxyethane; water for 20h; Heating;100%
With water at 100℃; for 1h;99%
With potassium phosphate In methanol at 120℃; under 5171.62 Torr; for 0.0333333h; Microwave irradiation;98%
tert-butyl (3-methylpyridin-2-yl)carbamate
138343-75-6

tert-butyl (3-methylpyridin-2-yl)carbamate

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
Stage #1: tert-butyl (3-methylpyridin-2-yl)carbamate With n-butyllithium; N,N-dimethyl-formamide In tetrahydrofuran at 0℃;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 50℃;
100%
With n-butyllithium In tetrahydrofuran; hexane; N,N-dimethyl-formamide at -15 - 25℃; for 17.5h;3.8 g
Stage #1: tert-butyl (3-methylpyridin-2-yl)carbamate With trimethylsilyl bromide In tetrahydrofuran; N,N-dimethyl-formamide at -30℃; for 1.75h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water; N,N-dimethyl-formamide at 0 - 40℃; for 3h;
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran / 4 h / 0 °C
1.2: 0 °C
2.1: hydrogenchloride / water / 8 h / Reflux
View Scheme
methyl bromide
74-83-9

methyl bromide

tert-butyl (3-methylpyridin-2-yl)carbamate
138343-75-6

tert-butyl (3-methylpyridin-2-yl)carbamate

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
Stage #1: methyl bromide; tert-butyl (3-methylpyridin-2-yl)carbamate In diethyl ether at 0℃; for 4h;
Stage #2: With N,N-dimethyl-formamide In diethyl ether at 0℃; for 0.5h; Concentration;
99.1%
7-azaindoline
10592-27-5

7-azaindoline

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With carbon dioxide; DBN; Eosin Y In dimethyl sulfoxide at 25 - 30℃; for 48h; Irradiation;97%
With potassium tert-butylate In decane at 150℃; for 36h; Inert atmosphere; Schlenk technique;90%
With 4-tert-Butylcatechol; oxygen In water at 20℃; for 20h; Green chemistry;90%
(Z)-2-amino-3-(2-ethoxyethenyl)pyridine
146336-83-6

(Z)-2-amino-3-(2-ethoxyethenyl)pyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With hydrogenchloride In methanol for 2h; Heating;94%
1-(2-amino-3-pyridinyl)-1-ethanone
65326-33-2

1-(2-amino-3-pyridinyl)-1-ethanone

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water at 90℃; pH=3; Temperature; pH-value; Microwave irradiation;93.2%
1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine
143141-23-5

1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With sodium t-butanolate In 1,4-dioxane at 80℃; for 3h; Inert atmosphere;93%
7-azaindole-2-carboxylic acid
136818-50-3

7-azaindole-2-carboxylic acid

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With zinc(II) oxide In toluene at 90℃; for 2h; Temperature;91.8%
1H-Pyrrolo[2,3-b]pyridine-7-oxide
55052-24-9

1H-Pyrrolo[2,3-b]pyridine-7-oxide

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With (4,4′-di-tert-butyl-2,2′-bipyridine)bis[(2-pyridinyl)phenyl]iridium(III) hexafluorophosphate; di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate In acetonitrile at 20℃; for 2h; Inert atmosphere; Irradiation; chemoselective reaction;91%
With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate In dichloromethane at 31℃; for 16h; Sealed tube; Irradiation;83%
With styrene; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; hydrazine hydrate In dimethyl sulfoxide at 20℃; for 13h; Inert atmosphere; Irradiation; chemoselective reaction;74%
1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine
348640-02-8

1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With cetyltrimethylammonim bromide; potassium hydroxide In tetrahydrofuran; water for 10h; Reagent/catalyst; Temperature; Time; Reflux; Green chemistry;90%
With potassium tert-butylate In dimethyl sulfoxide at 20℃; for 1h; Inert atmosphere; Darkness; Schlenk technique;87%
With formic acid; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 24h; Inert atmosphere; Sealed tube; Irradiation;70%
With caesium carbonate In tetrahydrofuran; methanol at 22℃; for 2h;
C7H6N4

C7H6N4

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With silver hexafluoroantimonate; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)] In benzene at 130℃; for 24h; Sealed tube; Glovebox; Inert atmosphere;86%
1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
4414-89-5

1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With hydrogenchloride; water for 48h; Reflux; Large scale;72.9%
5-fluoro-1H-pyrrolo[2,3‐b]pyridine
866319-00-8

5-fluoro-1H-pyrrolo[2,3‐b]pyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With 2-methyl-propan-1-ol; methanesulfonato(2-dicyclohexylphosphino -2’,6’-di-i-propoxy-1,1‘-biphenyl)(2’-amino-1,1’-biphenyl-2-yl)palladium(II); sodium tert-pentoxide In toluene at 80℃; for 48h; Sealed tube; Inert atmosphere;68%
tert-butyl (3-methylpyridin-2-yl)carbamate
138343-75-6

tert-butyl (3-methylpyridin-2-yl)carbamate

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
Stage #1: tert-butyl (3-methylpyridin-2-yl)carbamate With n-butyllithium In tetrahydrofuran at -10 - 0℃;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at 0 - 15℃;
Stage #3: With hydrogenchloride; water at -5 - 5℃;
67%
N-methyl-N-phenyl-N'-(2-(3-methylpyridine))formamidine
3189-06-8

N-methyl-N-phenyl-N'-(2-(3-methylpyridine))formamidine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran at -20℃; for 5h; Reagent/catalyst; Inert atmosphere;65%
2-phenyloxepino[2,3-b]pyridine
933768-06-0

2-phenyloxepino[2,3-b]pyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With acetamide; potassium tert-butylate In dimethyl sulfoxide at 80℃; for 48h; Inert atmosphere;52%
1-(phenylsulfonyl)-2-(trimethylsilyl)-1H-pyrrolo[2,3-b]pyridnie

1-(phenylsulfonyl)-2-(trimethylsilyl)-1H-pyrrolo[2,3-b]pyridnie

A

7-Azaindole
271-63-6

7-Azaindole

B

C10H14N2Si
1239864-85-7

C10H14N2Si

Conditions
ConditionsYield
With sodium t-butanolate In 1,4-dioxane at 80℃; for 3h; Inert atmosphere;A 44%
B 42%
3-ethenyl-2-nitropyridine
844503-09-9

3-ethenyl-2-nitropyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 1,10-Phenanthroline; carbon monoxide In acetonitrile at 120℃; under 4560.31 Torr; for 180h;41%
1-acetyl-2,3-dihydropyrrolo<2,3-b>pyridine
111097-45-1

1-acetyl-2,3-dihydropyrrolo<2,3-b>pyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With n-Dodecylamine In 1,2-dichloro-ethane for 1h; Irradiation;25%
(2-formylamino-pyridin-3-ylmethyl)-phosphonic acid diethyl ester

(2-formylamino-pyridin-3-ylmethyl)-phosphonic acid diethyl ester

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran; toluene at 90℃; for 0.5h;25%
1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde
4649-09-6

1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With perchloric acid adsorbed on silica gel; anthranilic acid amide In acetonitrile at 80℃; for 12h;25%
2-Amino-3-bromopyridine
13534-99-1

2-Amino-3-bromopyridine

Vinyl bromide
593-60-2

Vinyl bromide

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate; XPhos In tert-butyl alcohol at 110℃; for 24h; Sealed tube; Inert atmosphere;9%
N-(3-methyl-2-pyridinyl)formamide
4931-46-8

N-(3-methyl-2-pyridinyl)formamide

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With sodium ethanolate at 350℃;
With sodium formate; sodium anilide at 290 - 310℃;
With hydrogenchloride In diethyl ether; water; pentane at -20℃; Inert atmosphere; Reflux;
1H-pyrrolo[2,3-b]pyridine-3,6-dicarboxylic acid
99066-81-6

1H-pyrrolo[2,3-b]pyridine-3,6-dicarboxylic acid

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
at 320 - 330℃;
oxirane
75-21-8

oxirane

3-bromo-1H-pyrrolo[2,3-b]pyridine
74420-15-8

3-bromo-1H-pyrrolo[2,3-b]pyridine

A

7-Azaindole
271-63-6

7-Azaindole

B

1-(2-hydroxyethyl)-7-azaindole
90929-77-4

1-(2-hydroxyethyl)-7-azaindole

C

3-(2-hydroxyethyl)-7-azaindole
90929-76-3

3-(2-hydroxyethyl)-7-azaindole

Conditions
ConditionsYield
With n-butyllithium 1.) ether, 1,2-dimethoxyethane, -5 deg C, 1 h; 2.) 0 deg C, 5 h; Yield given. Multistep reaction. Yields of byproduct given;
2,2-Dimethyl-N-[3-(2-oxo-ethyl)-pyridin-2-yl]-propionamide

2,2-Dimethyl-N-[3-(2-oxo-ethyl)-pyridin-2-yl]-propionamide

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
With hydrogenchloride for 8h; Heating; Yield given;
1-(1H-pyrrolo[2,3-b]pyridin-1-yl)ethanone
53277-42-2

1-(1H-pyrrolo[2,3-b]pyridin-1-yl)ethanone

A

7-Azaindole
271-63-6

7-Azaindole

B

n-pentyl halide

n-pentyl halide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 89 percent / H2 / Pd-C / ethanol; 1,2-dimethoxy-ethane / 5 h / 20 °C
2: 25 percent / dodecylamine / 1,2-dichloro-ethane / 1 h / Irradiation
View Scheme
2,2-dimethyl-N-(3-methylpyridin-2-yl)propionamide
86847-66-7

2,2-dimethyl-N-(3-methylpyridin-2-yl)propionamide

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) n-BuLi / 1.) THF, -5 to 0 deg C, 4 h, 2.) THF, 0 deg C, 40 min
2: 5.5 M HCl / 8 h / Heating
View Scheme
3-hydroxy-2-nitropyridine
15128-82-2

3-hydroxy-2-nitropyridine

7-Azaindole
271-63-6

7-Azaindole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 52 percent / 60percent NaH / benzene / 60 h / Heating
2: 74 percent / Pd(PPh3)2Cl2, Et4NCl / acetonitrile / 1 h / Heating
3: 78 percent / H2 / W-2 Raney Ni / methanol
4: 94 percent / conc. HCl / methanol / 2 h / Heating
View Scheme
7-Azaindole
271-63-6

7-Azaindole

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one
83393-47-9

2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one

Conditions
ConditionsYield
Stage #1: 7-Azaindole With aluminum (III) chloride In dichloromethane at 20℃; for 1.5h; Inert atmosphere;
Stage #2: chloroacetyl chloride In dichloromethane at 0 - 20℃; for 18h; Inert atmosphere;
100%
With aluminium trichloride In carbon disulfide at 50℃; for 2h;82%
With aluminium trichloride In carbon disulfide at 50℃; for 2h; Product distribution;81%
7-Azaindole
271-63-6

7-Azaindole

methyl iodide
74-88-4

methyl iodide

1-methyl-1H-pyrrolo[2,3-b]pyridine
27257-15-4

1-methyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In N,N-dimethyl-formamide for 1h; Inert atmosphere;
100%
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In N,N-dimethyl-formamide for 1h; Inert atmosphere;
100%
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;
98%
7-Azaindole
271-63-6

7-Azaindole

(2-trimethylethylsilylethoxy)methyl chloride
76513-69-4

(2-trimethylethylsilylethoxy)methyl chloride

1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine
879132-46-4

1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 1.25h;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide; mineral oil for 1.25h;
100%
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 1.25h;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide; mineral oil for 1.25h;
100%
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 1h;
Stage #2: (2-trimethylethylsilylethoxy)methyl chloride In N,N-dimethyl-formamide; mineral oil for 1h;
100%
7-Azaindole
271-63-6

7-Azaindole

7-nitroquinoxaline-2(1H)-one
89898-96-4

7-nitroquinoxaline-2(1H)-one

7-nitro-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)-3,4-dihydro-1H-quinoxalin-2-one

7-nitro-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)-3,4-dihydro-1H-quinoxalin-2-one

Conditions
ConditionsYield
With trifluoroacetic acid In N,N-dimethyl-formamide at 80℃; for 1h;100%
7-Azaindole
271-63-6

7-Azaindole

n-pentyl halide

n-pentyl halide

1-pentyl-1H-pyrrolo[2,3-b]pyridine
912562-57-3

1-pentyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: n-pentyl halide In N,N-dimethyl-formamide at 20℃; for 15h;
100%
7-Azaindole
271-63-6

7-Azaindole

iodobenzene
591-50-4

iodobenzene

1-phenyl-1H-pyrrolo[2,3-b]pyridine

1-phenyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With potassium phosphate; trans-1,2-Diaminocyclohexane; copper(l) iodide In 1,4-dioxane at 110℃; for 24h;100%
With triethylamine In N,N-dimethyl-formamide at 110℃; for 3h;96%
With copper(l) iodide; manganese(II) fluoride; (1R,2R)-1,2-diaminocyclohexane; potassium hydroxide In water at 60℃; for 24h;93%
3-Bromopyridine
626-55-1

3-Bromopyridine

7-Azaindole
271-63-6

7-Azaindole

1-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine
847801-47-2

1-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With potassium phosphate; trans-1,2-Diaminocyclohexane; copper(l) iodide In 1,4-dioxane at 110℃; for 95h;100%
7-Azaindole
271-63-6

7-Azaindole

1-Bromopentane
110-53-2

1-Bromopentane

1-pentyl-1H-pyrrolo[2,3-b]pyridine
912562-57-3

1-pentyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 1-Bromopentane In N,N-dimethyl-formamide at 20℃; for 3.5h;
100%
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 1-Bromopentane In N,N-dimethyl-formamide at 20℃; for 3.5h;
100%
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 1-Bromopentane In N,N-dimethyl-formamide at 20℃; for 3.5h;
100%
7-Azaindole
271-63-6

7-Azaindole

1-bromo-hexane
111-25-1

1-bromo-hexane

C13H18N2
418795-22-9

C13H18N2

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃;100%
7-Azaindole
271-63-6

7-Azaindole

3-chloro-1H-pyrrolo[2,3-b]pyridine

3-chloro-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With N-chloro-succinimide In tetrachloromethane; chloroform for 4h; Ambient temperature;99%
With 1-aza-4,6,11-trioxa-5-boratricyclo[3.3.3.0(1,5)]undecane; nickel diacetate; chlorine at 90℃; for 3h; Reflux;99.3%
With 1,3-dichloro-5,5-dimethylhydantoin In 1,4-dioxane at 80℃; for 0.5h;92%
With sodium hypochlorite; sodium azide; acetic acid In water; toluene at 20℃; for 0.5h;91%
With 1-chloro-1λ3-benzo[d][1,2]iodaoxol-3(1H)-one In N,N-dimethyl-formamide at 20℃; for 12h; regioselective reaction;77%
7-Azaindole
271-63-6

7-Azaindole

lithium formate
556-63-8

lithium formate

1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde
4649-09-6

1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde

Conditions
ConditionsYield
With zinc diacetate In trifluoroacetic acid at 120℃; for 6h; Solvent; Concentration;99.1%
7-Azaindole
271-63-6

7-Azaindole

3-bromo-1H-pyrrolo[2,3-b]pyridine
74420-15-8

3-bromo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With 1-aza-4,6,11-trioxa-5-boratricyclo[3.3.3.0(1,5)]undecane; bromine; nickel diacetate at 100℃; for 3h; Temperature; Reflux;99%
With N-Bromosuccinimide In dichloromethane at 20℃; for 16h;96%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 4h; Cooling with ice;96%
7-Azaindole
271-63-6

7-Azaindole

benzenesulfonyl chloride
98-09-9

benzenesulfonyl chloride

1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine
143141-23-5

1-benzenesulfonyl-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 7-Azaindole With tetrabutylammomium bromide; sodium hydroxide In dichloromethane
Stage #2: benzenesulfonyl chloride In dichloromethane at 0 - 20℃;
99%
With dmap; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;98%
With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide In dichloromethane at 20℃; for 2h; Cooling with ice;95%
7-Azaindole
271-63-6

7-Azaindole

Z-ΔAla(N-Boc)-OMe
219851-84-0

Z-ΔAla(N-Boc)-OMe

Z-Ala[N-Boc-β-(7-azaindol-1-yl)]-OMe

Z-Ala[N-Boc-β-(7-azaindol-1-yl)]-OMe

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃; Addition; Michael addition;99%
7-Azaindole
271-63-6

7-Azaindole

3,5-dimethylphenyl iodide
22445-41-6

3,5-dimethylphenyl iodide

1-(3,5-dimethylphenyl)-1H-pyrrolo[2,3-b]pyridine

1-(3,5-dimethylphenyl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; (S,S)-1,2-diaminocyclohexane In 1,4-dioxane; dodecane at 110℃; for 24h;99%
With copper(I) oxide; potassium phosphate; N1,N2-bis(furan-2-ylmethyl)oxalamide In acetonitrile at 80℃;94%
With potassium phosphate monohydrate; iron(III) chloride hexahydrate; trans-N,N'-dimethylcyclohexane-1,2-diamine In water at 135℃; for 24h; Inert atmosphere;87%
7-Azaindole
271-63-6

7-Azaindole

n-butyl halide

n-butyl halide

N-butyl-7-azaindole
152956-02-0

N-butyl-7-azaindole

Conditions
ConditionsYield
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: n-butyl halide In N,N-dimethyl-formamide at 20℃; for 15h;
99%
7-Azaindole
271-63-6

7-Azaindole

tris(pentafluorophenyl)borate
1109-15-5

tris(pentafluorophenyl)borate

7-[tris(pentafluorophenyl)borane]-7-azaindole
879269-87-1

7-[tris(pentafluorophenyl)borane]-7-azaindole

Conditions
ConditionsYield
In dichloromethane (N2); a soln. of ligand added at room temp. to a soln. of B(C6F5)3, stirred for 1 h; evapd. (vac.); elem. anal.;99%
7-Azaindole
271-63-6

7-Azaindole

diethyl(methoxymethyl)amine
5888-29-9

diethyl(methoxymethyl)amine

N-((1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-N-ethylethanamine

N-((1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-N-ethylethanamine

Conditions
ConditionsYield
With hafnium tetrakis(trifluoromethanesulfonate) In dichloromethane at 20℃; for 0.2h; Inert atmosphere; regioselective reaction;99%
3-iodopyridine
1120-90-7

3-iodopyridine

7-Azaindole
271-63-6

7-Azaindole

1-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine
847801-47-2

1-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With manganese(II) fluoride; (S,S)-1,2-diaminocyclohexane; caesium carbonate In water at 130℃; for 24h; Reagent/catalyst;99%
With copper(l) iodide; manganese(II) fluoride; (1R,2R)-1,2-diaminocyclohexane; potassium hydroxide In water at 100℃; for 48h;94%
With copper(I) oxide; caesium carbonate In dimethyl sulfoxide at 100℃; for 24h; Reagent/catalyst; Solvent; Inert atmosphere;86%
7-Azaindole
271-63-6

7-Azaindole

bromopentene
1119-51-3

bromopentene

1-(pent-4-en-1-yl)-1H-pyrrolo[2,3-b]pyridine

1-(pent-4-en-1-yl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; Inert atmosphere;
Stage #2: bromopentene In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;
99%
7-Azaindole
271-63-6

7-Azaindole

hexamethylenetetramine
100-97-0

hexamethylenetetramine

1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde
4649-09-6

1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde

Conditions
ConditionsYield
With propionic acid In ethanol at 80℃; for 6h; Temperature;98.9%
Stage #1: 7-Azaindole; hexamethylenetetramine With acetic acid for 6h; Duff reaction; Heating;
Stage #2: With water at 20℃; Further stages.;
77%
With acetic acid In water for 12h; Heating / reflux;76%
7-Azaindole
271-63-6

7-Azaindole

cyclopentyl trimethoxysilane
143487-47-2

cyclopentyl trimethoxysilane

7-azaindolidine cyclopentyl dimethoxy silane

7-azaindolidine cyclopentyl dimethoxy silane

Conditions
ConditionsYield
Stage #1: 7-Azaindole With n-butyllithium In tetrahydrofuran at 20℃; for 2h; Inert atmosphere; Cooling with ice;
Stage #2: cyclopentyl trimethoxysilane In tetrahydrofuran at 0 - 20℃; for 8h; Inert atmosphere;
98.3%
7-Azaindole
271-63-6

7-Azaindole

1-Phenylethanol
98-85-1, 13323-81-4

1-Phenylethanol

C15H14N2

C15H14N2

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 2h; Friedel-Crafts Alkylation;98.3%
7-Azaindole
271-63-6

7-Azaindole

bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

7-Methoxycarbonylmethyl-1H-pyrrolo[2,3-b]pyridin-7-ium; bromide

7-Methoxycarbonylmethyl-1H-pyrrolo[2,3-b]pyridin-7-ium; bromide

Conditions
ConditionsYield
In benzene for 2h; Heating;98%
7-Azaindole
271-63-6

7-Azaindole

3-iodo-1H-pyrrolo[2,3-b]pyridine
23616-57-1

3-iodo-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
Stage #1: 7-Azaindole With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: With iodine In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere;
98%
With iodine; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 0.75h; Inert atmosphere;97%
With iodine; potassium hydroxide In N,N-dimethyl-formamide at 20℃;97%
7-Azaindole
271-63-6

7-Azaindole

n-propyl halide

n-propyl halide

N-propyl-7-azaindole
942262-52-4

N-propyl-7-azaindole

Conditions
ConditionsYield
Stage #1: 7-Azaindole With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: n-propyl halide In N,N-dimethyl-formamide at 20℃; for 15h;
98%
7-Azaindole
271-63-6

7-Azaindole

Phenyl glycidyl ether
122-60-1

Phenyl glycidyl ether

1-phenoxy-3-(1H-pyrrolo[2,3-b]pyridin-1-yl)propan-2-ol
1017278-65-7

1-phenoxy-3-(1H-pyrrolo[2,3-b]pyridin-1-yl)propan-2-ol

Conditions
ConditionsYield
ruthenium trichloride at 20℃; for 4h; Friedel-Crafts alkylation;98%
With ruthenium-exchanged FAU-Y zeolite at 20℃; for 0.5h; Friedel Crafts alkylation; Ultrasound irradiation; Neat (no solvent); regioselective reaction;98%

Raw Materials

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