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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Fluorotryptamine

Cas:576-16-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 576-16-9 with best quality

Cas:576-16-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

5-Fluorotryptamine 576-16-9

Cas:576-16-9

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Indole-3-ethanamine,5-fluoro- 576-16-9

Cas:576-16-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

5-Fluorotryptamine CAS:576-16-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme

5-Fluorotryptamine CAS:576-16-9

Cas:576-16-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Indole-3-ethanamine,5-fluoro-

Cas:576-16-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Indole-3-ethanamine,5-fluoro-

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Fluorotryptamine

Cas:576-16-9

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Indole-3-ethanamine,5-fluoro-

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3-(2-Aminoethyl)-5-fluoro-1Hindole

Cas:576-16-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

5-Fluorotryptamine

Cas:576-16-9

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

1H-Indole-3-ethanamine,5-fluoro-

Cas:576-16-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

DB BIOTECH CO., LTD

Q1: Are you a manufacturer Answer: Yes, we are factory founded on 2012.Q2: How to contact with us Click "contact supplier" And then send us message the product you interest in, you will get reply within 12 hours.Q3:Which kind of payment terms do you

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1H-Indole-3-ethanamine,5-fluoro-

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1H-Indole-3-ethanamine,5-fluoro-

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear oily liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as prim

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

5-Fluorotryptamine cas 576-16-9Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

5-Fluorotryptamine cas 576-16-9

Cas:576-16-9

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

576-16-9

Cas:576-16-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

SAGECHEM LIMITED

576-16-9 Application:intermediate

1H-Indole-3-ethanamine, 5-fluoro-

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-(2-Aminoethyl)-5-fluoro-1H-indole

Cas:576-16-9

Min.Order:0

Negotiable

Type:Other

inquiry

AstaTech ( Chengdu) BioPharmaceutical Corp.

Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

5-Fluorotryptamine 576-16-9

Cas:576-16-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

5-Fluorotryptamine 576-16-9

Cas:576-16-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

5-Fluorotryptamine

Cas:576-16-9

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

5-fluoro-3-(2-nitrovinyl)indole
208645-53-8

5-fluoro-3-(2-nitrovinyl)indole

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 40h;92%
With lithium aluminium tetrahydride In tetrahydrofuran Reflux;
(Ε)-5-fluoro-3-(2-nitroethenyl)-1Η-indole
214417-26-2

(Ε)-5-fluoro-3-(2-nitroethenyl)-1Η-indole

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; Inert atmosphere;76%
With lithium aluminium tetrahydride In tetrahydrofuran for 5h; Ambient temperature;
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; for 5h;
DL-5-fluorotryptophan
154-08-5

DL-5-fluorotryptophan

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; aromatic L-amino acid decarboxylase In various solvent(s) at 30℃; for 48h;41%
With NH4OH-NH4Cl buffer; pyridoxal 5'-phosphate at 30℃; for 0.5h; relative rate of CO2 evolution by aromatic L-amino acid decarboxylase from Micrococcus percitreus;
5-fluoro-3-(2-nitroethyl)-1Η-indole

5-fluoro-3-(2-nitroethyl)-1Η-indole

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Stage #1: 5-fluoro-3-(2-nitroethyl)-1Η-indole With ammonium chloride In tetrahydrofuran; ethanol at 85℃; for 0.166667h;
Stage #2: With iron
26.2%
3-(2-amino-ethyl)-5-fluoro-indole-2-carboxylic acid
1512-99-8

3-(2-amino-ethyl)-5-fluoro-indole-2-carboxylic acid

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With hydrogenchloride
4-aminobutyrylaldehyde diethylacetal
6346-09-4

4-aminobutyrylaldehyde diethylacetal

4-fluorophenylhydrazine
371-14-2

4-fluorophenylhydrazine

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With zinc(II) chloride at 180℃;
5-fluoro-1H-indole
399-52-0

5-fluoro-1H-indole

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: POCl3 / 0.25 h / 20 °C
1.2: CaCO3 / 1,2-dichloro-ethane / 0.5 h / Heating
2.1: 60 percent / ammonium acetate / 1.5 h / Heating
3.1: LiAlH4 / tetrahydrofuran / 5 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 1.) POCl3, 2.) CaCO3 / 1.) RT, 15 min, 2.) 1,2-dichloroethane, reflux, 30 min
2: 60 percent / ammonium acetate / 1.5 h / Heating
3: LiAlH4 / tetrahydrofuran / 5 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1.1: trichlorophosphate / 1.25 h / 0 - 38 °C
1.2: 0.08 h / 170 °C
2.1: ammonium acetate / 1.5 h / Reflux
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 40 h / 0 - 20 °C
View Scheme
Multi-step reaction with 4 steps
1: diethyl ether / 3 h / 0 - 20 °C
2: diethyl ether / 1 h / 20 °C
3: ammonia / water / 24 h / 20 °C
4: lithium aluminium tetrahydride / tetrahydrofuran / 10 h / Reflux
View Scheme
5-fluoro-1H-indole-3-carbaldehyde
2338-71-8

5-fluoro-1H-indole-3-carbaldehyde

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 60 percent / ammonium acetate / 1.5 h / Heating
2: LiAlH4 / tetrahydrofuran / 5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 60 percent / ammonium acetate / 1.5 h / Heating
2: LiAlH4 / tetrahydrofuran / 5 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: piperidine; acetic acid / benzene / Reflux
2: lithium aluminium tetrahydride / tetrahydrofuran / Reflux
View Scheme
Multi-step reaction with 2 steps
1: ammonium acetate / 1.5 h / Reflux
2: lithium aluminium tetrahydride / tetrahydrofuran / 40 h / 0 - 20 °C
View Scheme
piperidine-2,3-dione-3-(4-fluoro-phenylhydrazone)
721-58-4

piperidine-2,3-dione-3-(4-fluoro-phenylhydrazone)

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aqueous HCl; acetic acid
2: aq.-ethanolic KOH
3: aqueous HCl
View Scheme
6-fluoro-2,3,4,9-tetrahydro-β-carbolin-1-one
778-73-4

6-fluoro-2,3,4,9-tetrahydro-β-carbolin-1-one

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq.-ethanolic KOH
2: aqueous HCl
View Scheme
3-(2-nitroethyl)-6-fluoroindole
937256-55-8

3-(2-nitroethyl)-6-fluoroindole

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With hydrazine; nickel In ethanol at 20℃; for 1h;
2-(3-chloropropyl)-1,3-dioxolane
16686-11-6

2-(3-chloropropyl)-1,3-dioxolane

4-fluorophenylhydrazine
371-14-2

4-fluorophenylhydrazine

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
In ethanol; water at 95℃; for 1h;
C15H19FN2O2

C15H19FN2O2

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Stage #1: C15H19FN2O2 With trifluoroacetic acid In dichloromethane at 25℃; Inert atmosphere;
Stage #2: With sodium hydroxide In dichloromethane; water at 25℃; pH=Ca. 12 - Ca. 13; Inert atmosphere;
12.6 mg
With trifluoroacetic acid In dichloromethane at 0 - 25℃; Inert atmosphere;12.6 mg
C18H13FN2O2
1198292-69-1

C18H13FN2O2

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With hydrazine In ethanol at 20℃; Combinatorial reaction / High throughput screening (HTS);
3-(2-azidoethyl)-5-fluoro-1H-indole
1258297-02-7

3-(2-azidoethyl)-5-fluoro-1H-indole

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In ethanol under 3102.97 Torr;
4-chloro-1-hydroxy-1-butanesulfonate sodium
54322-20-2

4-chloro-1-hydroxy-1-butanesulfonate sodium

4-fluorophenyhydrazine hydrochloride
823-85-8

4-fluorophenyhydrazine hydrochloride

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With disodium hydrogenphosphate In ethanol at 70℃; for 6h;
4-fluoroaniline
371-40-4

4-fluoroaniline

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium nitrite; hydrogenchloride / water / 1 h / 0 - 5 °C
1.2: 4 h / 80 - 100 °C
2.1: disodium hydrogenphosphate / ethanol / 6 h / 70 °C
View Scheme
C10H7FN2O2

C10H7FN2O2

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran for 10h; Reflux;
methyl 2-(5-fluoro-1H-indol-3-yl)-2-oxoacetate
408356-39-8

methyl 2-(5-fluoro-1H-indol-3-yl)-2-oxoacetate

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonia / water / 24 h / 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 10 h / Reflux
View Scheme
2-(5-fluoro-1H-indol-3-yl)-2-oxoacetyl chloride
3828-09-9

2-(5-fluoro-1H-indol-3-yl)-2-oxoacetyl chloride

5-fluorotryptamine
576-16-9

5-fluorotryptamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: diethyl ether / 1 h / 20 °C
2: ammonia / water / 24 h / 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 10 h / Reflux
View Scheme
5-fluorotryptamine
576-16-9

5-fluorotryptamine

phenyl chloroformate
1885-14-9

phenyl chloroformate

[2-(5-fluoro-1H-indol-3-yl)-ethyl]-carbamic acid phenyl ester

[2-(5-fluoro-1H-indol-3-yl)-ethyl]-carbamic acid phenyl ester

Conditions
ConditionsYield
With pyridine In dichloromethane at 20℃; for 24h; Heating / reflux;100%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

tert-butyl N-[2-(5-fluoro-1H-indol-3-yl)ethyl]carbamate
1059175-54-0

tert-butyl N-[2-(5-fluoro-1H-indol-3-yl)ethyl]carbamate

Conditions
ConditionsYield
In 1,4-dioxane at 20℃; for 16h;99%
With triethylamine In tetrahydrofuran at 10℃; for 1h; Inert atmosphere;83%
With triethylamine In tetrahydrofuran at 10℃; for 1h;83%
formaldehyd
50-00-0

formaldehyd

5-fluorotryptamine
576-16-9

5-fluorotryptamine

2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine
22120-36-1

2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine

Conditions
ConditionsYield
With sodium acetate; sodium cyanoborohydride In methanol at 0 - 25℃; for 5h;97.3%
With sodium cyanoborohydride; acetic acid In methanol for 2h; pH=6.5; Reflux;
5-fluorotryptamine
576-16-9

5-fluorotryptamine

salicylaldehyde
90-02-8

salicylaldehyde

N-(2-hydroxyphenylmethyl)-2-(5-fluoro-3-indolyl)ethylamine

N-(2-hydroxyphenylmethyl)-2-(5-fluoro-3-indolyl)ethylamine

Conditions
ConditionsYield
Stage #1: 5-fluorotryptamine; salicylaldehyde In ethanol for 1h;
Stage #2: With sodium cyanoborohydride In ethanol
92.5%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

7-(trifluoromethyl)-3,4,5,6-tetrahydro-2H-azepine
1146222-77-6

7-(trifluoromethyl)-3,4,5,6-tetrahydro-2H-azepine

5-(6-fluoro-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)pentan-1-amine

5-(6-fluoro-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)pentan-1-amine

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane at 20℃; for 168h; Pictet-Spengler Synthesis;90%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

5-(4-hydroxyphenyl)-2-furancarboxaldehyde
13130-10-4

5-(4-hydroxyphenyl)-2-furancarboxaldehyde

4-[5-({[2-(5-fluoro-1H-indol-3-yl)ethyl]amino}methyl)furan-2-yl]phenol

4-[5-({[2-(5-fluoro-1H-indol-3-yl)ethyl]amino}methyl)furan-2-yl]phenol

Conditions
ConditionsYield
Stage #1: 5-fluorotryptamine; 5-(4-hydroxyphenyl)-2-furancarboxaldehyde In methanol at 20℃; Molecular sieve;
Stage #2: With sodium tetrahydroborate In methanol for 1h; Molecular sieve;
82%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

(4-oxo-5-thiophen-2-ylmethylen-2-thioxothiazolidine-3-yl)acetyl chloride

(4-oxo-5-thiophen-2-ylmethylen-2-thioxothiazolidine-3-yl)acetyl chloride

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]-2-[(5Z)-4-oxo-5-thiophen-2-ylmethylen-2-thioxothiazolidin-3-yl]acetamide

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]-2-[(5Z)-4-oxo-5-thiophen-2-ylmethylen-2-thioxothiazolidin-3-yl]acetamide

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane for 0.5h; Heating;82%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

3-methylsalicylic acid
83-40-9

3-methylsalicylic acid

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxy-3-methylbenzamide

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxy-3-methylbenzamide

Conditions
ConditionsYield
Stage #1: 3-methylsalicylic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: 5-fluorotryptamine In acetone at 20℃; for 24h;
79.43%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

2-hydroxy-p-toluic acid
50-85-1

2-hydroxy-p-toluic acid

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxy-4-methylbenzamide

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxy-4-methylbenzamide

Conditions
ConditionsYield
Stage #1: 2-hydroxy-p-toluic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: 5-fluorotryptamine In acetone at 20℃; for 24h;
79.43%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

salicylic acid
69-72-7

salicylic acid

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

Conditions
ConditionsYield
Stage #1: salicylic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: 5-fluorotryptamine In acetone at 20℃; for 24h;
78.23%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

tert-butyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)-5-fluoro-1H-indole-1-carboxylate

tert-butyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)-5-fluoro-1H-indole-1-carboxylate

Conditions
ConditionsYield
With dmap In dichloromethane at 0 - 20℃;77%
With dmap In dichloromethane at 0 - 20℃; for 1h;46%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

4-chlorosalicylic acid
5106-98-9

4-chlorosalicylic acid

4-chloro-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

4-chloro-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

Conditions
ConditionsYield
Stage #1: 4-chlorosalicylic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: 5-fluorotryptamine In acetone at 20℃; for 24h;
75.54%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

5-phenylfuran-2(3H)-one

5-phenylfuran-2(3H)-one

(11bS)-8-fluoro-11b-phenyl-1,2,5,6,11,11b-hexahydro-3H-indolizino[8,7-b]indol-3-one
1178541-58-6

(11bS)-8-fluoro-11b-phenyl-1,2,5,6,11,11b-hexahydro-3H-indolizino[8,7-b]indol-3-one

Conditions
ConditionsYield
With (R)-3,3'-bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate In toluene at 110℃; for 24h; optical yield given as %ee; enantioselective reaction;73%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

6-(trifluoromethyl)-2,3,4,5-tetrahydropyridine
1146222-76-5

6-(trifluoromethyl)-2,3,4,5-tetrahydropyridine

4-(6-fluoro-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)butan-1-amine

4-(6-fluoro-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)butan-1-amine

Conditions
ConditionsYield
With camphor-10-sulfonic acid In water at 130℃; for 14h; Pictet-Spengler Synthesis;73%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

19-nor-Δ1,3,5(10)-22α-spirostatriene-3-ol
24036-91-7

19-nor-Δ1,3,5(10)-22α-spirostatriene-3-ol

(22R,25R)-3β-(5-fluoro-1H-indole-3-ethylamine-carboxylate)-1,3,5(10)-trien-20α-spirostan

(22R,25R)-3β-(5-fluoro-1H-indole-3-ethylamine-carboxylate)-1,3,5(10)-trien-20α-spirostan

Conditions
ConditionsYield
Stage #1: bis(trichloromethyl) carbonate; 19-nor-Δ1,3,5(10)-22α-spirostatriene-3-ol With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 0.5h; Inert atmosphere;
Stage #2: 5-fluorotryptamine In dichloromethane at 20℃; for 3h; Inert atmosphere;
73%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

5-bromosalicyclic acid
89-55-4

5-bromosalicyclic acid

5-bromo-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

5-bromo-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

Conditions
ConditionsYield
Stage #1: 5-bromosalicyclic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: 5-fluorotryptamine In acetone at 20℃; for 24h;
71.54%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide
1024493-18-2

N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 24℃; for 4h;71%
With triethylamine In dichloromethane at 0 - 20℃; for 6h;
With triethylamine In dichloromethane at 0℃;
With triethylamine In dichloromethane at 20℃; for 4h;
5-fluorotryptamine
576-16-9

5-fluorotryptamine

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

5-chloro-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

5-chloro-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-hydroxybenzamide

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 20℃; for 4h;
Stage #2: 5-fluorotryptamine In acetone at 20℃; for 24h;
70.54%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

Methoxyacetyl chloride
38870-89-2

Methoxyacetyl chloride

C13H15FN2O2
1292285-47-2

C13H15FN2O2

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 26℃; for 2h;68.2%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

methyl (2E)-3-(4-formylphenyl)acrylate
7560-50-1, 71093-79-3, 58045-41-3

methyl (2E)-3-(4-formylphenyl)acrylate

3-[4-[[[2-(5-fluoro-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-(2E)-2-propenoic acid methyl ester

3-[4-[[[2-(5-fluoro-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-(2E)-2-propenoic acid methyl ester

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride In tetrahydrofuran67%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

1-(3-chloro-5-(trifluoromethyl)pyrid-2-yl)-4-piperidone
339029-35-5

1-(3-chloro-5-(trifluoromethyl)pyrid-2-yl)-4-piperidone

C21H19ClF4N4

C21H19ClF4N4

Conditions
ConditionsYield
Stage #1: 5-fluorotryptamine; 1-(3-chloro-5-(trifluoromethyl)pyrid-2-yl)-4-piperidone In chloroform for 1h; Molecular sieve; Heating / reflux;
Stage #2: With hydrogenchloride; water In chloroform Heating / reflux;
Stage #3: With sodium hydrogencarbonate In chloroform; water
67%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

1-((6-bromo-5-methylimidazo[1,2-a]pyridin-2-yl)methyl)-1H-1,2,3-triazole-4-carboxylic acid

1-((6-bromo-5-methylimidazo[1,2-a]pyridin-2-yl)methyl)-1H-1,2,3-triazole-4-carboxylic acid

1-((6-bromo-5-methylimidazo[1,2-a]pyridin-2-yl)methyl)-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-1H-1,2,3-triazole-4-carboxamide

1-((6-bromo-5-methylimidazo[1,2-a]pyridin-2-yl)methyl)-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-1H-1,2,3-triazole-4-carboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 3h;66%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

N,N-dimethyl-4-oxopiperidinium iodide
26822-37-7

N,N-dimethyl-4-oxopiperidinium iodide

1-[2-(5-fluoro-1H-indol-3-yl)-ethyl]-piperidin-4-one
151191-79-6

1-[2-(5-fluoro-1H-indol-3-yl)-ethyl]-piperidin-4-one

Conditions
ConditionsYield
With potassium carbonate In ethanol65%
5-fluorotryptamine
576-16-9

5-fluorotryptamine

2-trifluoromethyl-Δ1-pyrroline

2-trifluoromethyl-Δ1-pyrroline

3-(6-fluoro-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propan-1-amine

3-(6-fluoro-1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)propan-1-amine

Conditions
ConditionsYield
With camphor-10-sulfonic acid In water at 130℃; for 14h; Pictet-Spengler Synthesis;63%
but-3-yne-1-sulfonyl chloride

but-3-yne-1-sulfonyl chloride

5-fluorotryptamine
576-16-9

5-fluorotryptamine

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]but-3-yne-1-sulfonamide
1452838-28-6

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]but-3-yne-1-sulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at -78℃; Inert atmosphere;57%
(4-dimethylamino-4-phenyl-cyclohexylmethyl)-carbamic acid phenyl ester
695212-95-4

(4-dimethylamino-4-phenyl-cyclohexylmethyl)-carbamic acid phenyl ester

5-fluorotryptamine
576-16-9

5-fluorotryptamine

1-(4-dimethylamino-4-phenyl-cyclohexylmethyl)-3-[2-(5-fluoro-1H-indol-3-yl)-ethyl]-urea

1-(4-dimethylamino-4-phenyl-cyclohexylmethyl)-3-[2-(5-fluoro-1H-indol-3-yl)-ethyl]-urea

Conditions
ConditionsYield
In 1,4-dioxane for 24h; Heating / reflux;56%
In 1,4-dioxane for 24h; Heating / reflux;
(4,6-dimethylpyrimidin-2-yl)cyanamide
55474-90-3

(4,6-dimethylpyrimidin-2-yl)cyanamide

5-fluorotryptamine
576-16-9

5-fluorotryptamine

3-{2-[((4,6-dimethylpyrimidin-2-ylamino)(imino)methyl)amino]ethyl}-5-fluoro-1H-indole

3-{2-[((4,6-dimethylpyrimidin-2-ylamino)(imino)methyl)amino]ethyl}-5-fluoro-1H-indole

Conditions
ConditionsYield
In 1,4-dioxane Heating;53%
2-methylmorpholine
27550-90-9

2-methylmorpholine

5-fluorotryptamine
576-16-9

5-fluorotryptamine

4-nitrobenzyl chloroformate
4457-32-3

4-nitrobenzyl chloroformate

N-(p-Nitrobenzyloxycarbonyl)-5-fluorotryptamine
163885-14-1

N-(p-Nitrobenzyloxycarbonyl)-5-fluorotryptamine

Conditions
ConditionsYield
In dichloromethane53%

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