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Hangzhou Sartort Biopharma Co., Ltd

Appearance:Off-white to yellow fine powder Storage:R.T Package:25kg/drum Application:Chemicals Transportation:Express/Sea/Air Port:Any port in China

5% Vitamin K1 cas 84-80-0

Cas:84-80-0

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

ShangHai Soyoung Biotechnology Inc

Trade Assurance Get full protection for your orders 100% Product quality protection 100% On-time shipment protection 100% Payment protection Appearance:A clear intense yellow, viscous, oily liquid Storage:stored in sealed containers,cool dry place

Vitamin K1 oil phytomenadione

Cas:84-80-0

Min.Order:1 Kilogram

FOB Price: $2248.0

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

CAS No.: 84-80-0 Other Names: Vk1 MF: C31H46O2 EINECS No.: / Place of Origin: Shaanxi, China (Mainland) Type: Antibiotic and Antimicrobial Agents, Auxiliarie

high quality Vitamin K1 84-80-0 with best price

Cas:84-80-0

Min.Order:1 Kilogram

FOB Price: $3500.0

Type:Other

inquiry

Josun International Limited

Dear Friend, welcome you choose us ! And thank you very much for trust us! We are professional API and Chemcial supplier , we can provide you with good price and good service. ================================================== Product N

Vitamin K1 / Phytonadione

Cas:84-80-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

Vitamin K1

Cas:84-80-0

Min.Order:0

Negotiable

Type:Other

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Vitamin K1 Manufacturer/High quality/Best price/In stock

Cas:84-80-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF Vitamin K1 phylloquinone 84-80-0

Cas:84-80-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Clear,yellow to amber,very viscous, orderless or practically odorless liquid Co

Top purity Vitamin K1 with high quality and best price cas:84-80-0

Cas:84-80-0

Min.Order:1 Gram

FOB Price: $2.0 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

high quality Vitamin K1 with best price CAS NO.84-80-0

Cas:84-80-0

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Yellow viscous liquid Storage:2-8°C Package:1kg/tin; 25kg

Factory supply Vitamin K1 oil CAS 84-80-0 with favorable price

Cas:84-80-0

Min.Order:5 Kilogram

FOB Price: $100.0

Type:Trading Company

inquiry

Hangzhou Think Chemical Co. Ltd

Vitamin K1 (Phytomenadione) CAS:84-80-0 USP42 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketin

Vitamin K1 (Phytomenadione) 1% stock with GMP

Cas:84-80-0

Min.Order:500 Gram

Negotiable

Type:Other

inquiry

Hefei TNJ chemical industry co.,ltd

1, Full experience of large numbers containers loading in main Chinese seaports 2, Packing with pallet as buyer's special request 3, Best service after shipment with e-mail 4, Cargoes together with container sales service available

Hot sale powder and oil form Vitamin K1 84-80-0

Cas:84-80-0

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Vitamin K1

Cas:84-80-0

Min.Order:1

Negotiable

Type:Other

inquiry

HANGZHOU CLAKE BIOTECH CO.,LTD

1. GMP AVALIABLE ; 2. IN STOCK 3. FAST REPLY QUALIFED ; EFFICIENCY; RESPONSIBLE Vitmain K1 5% ,20% ,pure oil all avaliable Appearance:Yellow or orange-yellow crystalline powder Storage:in cool Package:25kg/drum Application:act

vitamin K1

Cas:84-80-0

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Food Grade Vitamin K1 84-80-0 HACCP Manufacturer

Cas:84-80-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

VK1

Cas:84-80-0

Min.Order:10 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Vitamin K1

Cas:84-80-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Shanxi Zorui Biotechnology Co.Ltd.

Zorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ

ISO Phytomenadione Vitamin Fine Powder Vitamin K1 Oil CAS 84-80-0

Cas:84-80-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Vitamin K1

Cas:84-80-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Appearance:Yellow to Dark Yellow viscous liquid Storage:2-8°C Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:shanghai

Cas no.84-80-0 98% Vitamin K1

Cas:84-80-0

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Why Choose Us With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in eac

Vitamin K1/Phylloquinone CASno: 84-80-0

Cas:84-80-0

Min.Order:1 Metric Ton

FOB Price: $10.0 / 20.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 84-80-0 with best quality

Cas:84-80-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Vitamin K1/ LIDE PHARMA- Factory supply / Best price

Cas:84-80-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

VITAMIN K1;CAS;84-80-0

Cas:84-80-0

Min.Order:1 Metric Ton

FOB Price: $20.0 / 30.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name:Viatmin k1 Synonyms: 2-Methyl-3-phytyl-1,4-naphthoquinone CAS:84-80-0 MF: C31H46O2 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Nutrition Enhancers Transportation:By sea o

Vitamin K1 CAS:84-80-0

Cas:84-80-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

1,4-Naphthalenedione,2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecen-1-yl]-CAS NO.: 84-80-0

Cas:84-80-0

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Yellow transparent viscous liquid Storage:Store in sealed co

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical inte

Vitamin K1 99% Hot supplier

Cas:84-80-0

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: Vitamin K1 Structure: Formula: C31H46O2 Molecular Weight : 450.7 Synonyms: Kativn K1;Phytomenadione (Vitamin K1);vitamin K1 micro-capsule;PHYLLOQUINONE;PHY

Factory Supply Viramin K1

Cas:84-80-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Synthetic route

2-(chloromethyl)-3-methylnaphthalene-1,4-dione
31599-79-8

2-(chloromethyl)-3-methylnaphthalene-1,4-dione

trimethylaluminum
75-24-1

trimethylaluminum

(6R,10R)-6,10,14-trimethyl-pentadec-1-yne
135011-17-5

(6R,10R)-6,10,14-trimethyl-pentadec-1-yne

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Stage #1: trimethylaluminum; (6R,10R)-6,10,14-trimethyl-pentadec-1-yne With zirconocene dichloride In 1,2-dichloro-ethane
Stage #2: 2-(chloromethyl)-3-methylnaphthalene-1,4-dione With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran Further stages.;
86%
4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate
50281-47-5

4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
With sodium dithionite; potassium hydroxide In methanol; n-heptane; water at 18 - 20℃; for 1h;63.6%
With sodium dithionite; potassium hydroxide In methanol; n-heptane; water at 18 - 20℃; for 1h;63.6%
menadione
58-27-5

menadione

phytol
150-86-7

phytol

A

phytomenadione
84-80-0

phytomenadione

B

2,3-benzo-5-methyl-5-phytylcyclohexane-1,4-dione
74610-11-0

2,3-benzo-5-methyl-5-phytylcyclohexane-1,4-dione

Conditions
ConditionsYield
With bis(benzonitrile)palladium(II) dichloride; tin(II) bromide In N,N-dimethyl-formamide at 50℃; for 24h;A 46%
B 42%
menadione
58-27-5

menadione

phytol
150-86-7

phytol

A

2,3-benzo-5-methyl-5-phytylcyclohexane-1,4-dione

2,3-benzo-5-methyl-5-phytylcyclohexane-1,4-dione

B

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
With bis(benzonitrile)palladium(II) dichloride; tin(II) bromide In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere;A 42%
B 46%
2-methyl-3-phytyl-1,4-naphthohydroquinone monopropionate

2-methyl-3-phytyl-1,4-naphthohydroquinone monopropionate

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
With sodium dithionite; sodium hydroxide In ethanol; water at 25℃; for 4h;22.7%
With sodium dithionite; sodium hydroxide In ethanol; water at 25℃; for 4h;22.7%
2-methyl-1,4-naphthohydroquinone
481-85-6

2-methyl-1,4-naphthohydroquinone

phytol
150-86-7

phytol

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
With boron trifluoride anschliessend Behandeln mit Ag2O;
4-acetoxy-3-methyl-1-naphthol
2211-27-0

4-acetoxy-3-methyl-1-naphthol

phytol
150-86-7

phytol

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multistep reaction;
Benzoesaeure-<4-hydroxy-2-methyl-3-((2'E,7'R,11'R)-phytyl)-1-naphthyl>ester
5546-13-4

Benzoesaeure-<4-hydroxy-2-methyl-3-((2'E,7'R,11'R)-phytyl)-1-naphthyl>ester

A

phytomenadione
84-80-0

phytomenadione

B

(2'Z,7'R,11'R)-Phyllochinon

(2'Z,7'R,11'R)-Phyllochinon

Conditions
ConditionsYield
With potassium hydroxide In methanol; hexane; water for 2h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
dihydrophylloquinone

dihydrophylloquinone

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
With diethyl ether; silver(l) oxide
1-iodo-2,6,10-trimethyl-undecane

1-iodo-2,6,10-trimethyl-undecane

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: Li2CuCl4
1.2: KOH / methanol
2.1: Cp2ZrCl2 / 1,2-dichloro-ethane
2.2: 86 percent / Pd(PPh3)4 / tetrahydrofuran
View Scheme
(2E,7R,11R)-Phytyl-methylaether
66432-64-2

(2E,7R,11R)-Phytyl-methylaether

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
1-bromo-3,7,11-trimethyldodecane
17081-92-4

1-bromo-3,7,11-trimethyldodecane

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 65 percent Chromat. / Mg / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1: Mg / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E)-4-methoxy-2-methyl-but-2-enal
4356-74-5

(E)-4-methoxy-2-methyl-but-2-enal

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 90 percent / NaBH4 / ethanol / 1 h / 0 °C
2: 67 percent / pyridine / 3 h / Ambient temperature
3: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: 90 percent / NaBH4 / ethanol / 1 h / 0 °C
2: 41 percent / pyridine / CHCl3 / 0.5 h / 0 °C
3: 65 percent Chromat. / Mg / Li2CuCl4 / tetrahydrofuran
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E/Z)-4-Methoxy-2-methyl-2-butenal
58511-43-6

(E/Z)-4-Methoxy-2-methyl-2-butenal

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: NaBH4 / ethanol / 1 h / 0 °C
2: 67 percent / pyridine / 3 h / Ambient temperature
3: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: NaBH4 / ethanol / 1 h / 0 °C
2: 41 percent / pyridine / CHCl3 / 0.5 h / 0 °C
3: 65 percent Chromat. / Mg / Li2CuCl4 / tetrahydrofuran
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E)-4-Methoxy-2-methyl-2-butenol
65527-93-7

(E)-4-Methoxy-2-methyl-2-butenol

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 67 percent / pyridine / 3 h / Ambient temperature
2: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
4: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 4 steps
1: 41 percent / pyridine / CHCl3 / 0.5 h / 0 °C
2: 65 percent Chromat. / Mg / Li2CuCl4 / tetrahydrofuran
4: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(3R,7R)-3,7,11-trimethyl-dodecyl bromide
65528-01-0

(3R,7R)-3,7,11-trimethyl-dodecyl bromide

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E/Z)-4-Methoxy-2-methyl-2-butenal-dimethylacetal
65527-95-9, 66432-59-5

(E/Z)-4-Methoxy-2-methyl-2-butenal-dimethylacetal

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 92 percent / p-toluenesulfonic acid, water / tetrahydrofuran / 16 h / Ambient temperature
2: 90 percent / NaBH4 / ethanol / 1 h / 0 °C
3: 67 percent / pyridine / 3 h / Ambient temperature
4: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
6: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 6 steps
1: 92 percent / p-toluenesulfonic acid, water / tetrahydrofuran / 16 h / Ambient temperature
2: 90 percent / NaBH4 / ethanol / 1 h / 0 °C
3: 41 percent / pyridine / CHCl3 / 0.5 h / 0 °C
4: 65 percent Chromat. / Mg / Li2CuCl4 / tetrahydrofuran
6: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 6 steps
1: H3PO4 / tetrahydrofuran / 0.08 h / Ambient temperature
2: 90 percent / NaBH4 / ethanol / 1 h / 0 °C
3: 67 percent / pyridine / 3 h / Ambient temperature
4: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
6: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 6 steps
1: H3PO4 / tetrahydrofuran / 0.08 h / Ambient temperature
2: 90 percent / NaBH4 / ethanol / 1 h / 0 °C
3: 41 percent / pyridine / CHCl3 / 0.5 h / 0 °C
4: 65 percent Chromat. / Mg / Li2CuCl4 / tetrahydrofuran
6: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Essigsaeure-<(E)-4-methoxy-2-methyl-2-butenyl>ester
65527-94-8

Essigsaeure-<(E)-4-methoxy-2-methyl-2-butenyl>ester

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E)-1-O-acetyl-4-chloro-3-methyl-2-buten-1-ol
24529-80-4

(E)-1-O-acetyl-4-chloro-3-methyl-2-buten-1-ol

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 73 percent / Ba(OH)2 / methanol
2: POCl3 / 0.5 h
3: dimethylformamide / 3 h / 80 °C
4: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
6: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 8 steps
1: 73 percent / Ba(OH)2 / methanol
2: POCl3 / 0.5 h
3: dimethylformamide / 3 h / 80 °C
4: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
5: 94 percent / pyridinium-p-toluolsulfonate / ethanol / 1.5 h / 55 °C
6: 82 percent / NaH (in oil) / dimethylformamide / Ambient temperature
8: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 6 steps
1: 73 percent / Ba(OH)2 / methanol
2: POCl3 / 0.5 h
3: dimethylformamide / 3 h / 80 °C
4: 57 percent Chromat. / Mg / CuI / tetrahydrofuran
6: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E)-4-chloro-3-methyl-2-buten-1-ol
53170-97-1

(E)-4-chloro-3-methyl-2-buten-1-ol

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: POCl3 / 0.5 h
2: dimethylformamide / 3 h / 80 °C
3: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 7 steps
1: POCl3 / 0.5 h
2: dimethylformamide / 3 h / 80 °C
3: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
4: 94 percent / pyridinium-p-toluolsulfonate / ethanol / 1.5 h / 55 °C
5: 82 percent / NaH (in oil) / dimethylformamide / Ambient temperature
7: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: POCl3 / 0.5 h
2: dimethylformamide / 3 h / 80 °C
3: 57 percent Chromat. / Mg / CuI / tetrahydrofuran
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Benzoesaeure-<4-hydroxy-2-methyl-1-naphthyl>ester
2211-28-1

Benzoesaeure-<4-hydroxy-2-methyl-1-naphthyl>ester

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
racemic Hexahydrofarnesylmagnesium bromid
42933-01-7

racemic Hexahydrofarnesylmagnesium bromid

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 54 percent Chromat. / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1: 84 percent Chromat. / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: 84 percent Chromat. / Li2CuCl4 / tetrahydrofuran
2: 94 percent / pyridinium-p-toluolsulfonate / ethanol / 1.5 h / 55 °C
3: 82 percent / NaH (in oil) / dimethylformamide / Ambient temperature
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E/Z)-<2-Methyl-4-(2'-tetrahydropyranyloxy)-2-butenyl>chlorid
55453-94-6

(E/Z)-<2-Methyl-4-(2'-tetrahydropyranyloxy)-2-butenyl>chlorid

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dimethylformamide / 3 h / 80 °C
2: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
4: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 6 steps
1: dimethylformamide / 3 h / 80 °C
2: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
3: 94 percent / pyridinium-p-toluolsulfonate / ethanol / 1.5 h / 55 °C
4: 82 percent / NaH (in oil) / dimethylformamide / Ambient temperature
6: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 4 steps
1: dimethylformamide / 3 h / 80 °C
2: 57 percent Chromat. / Mg / CuI / tetrahydrofuran
4: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
p-Toluolsulfonsaeure-<(E)-4-methoxy-2-methyl-2-butenyl>ester
83125-45-5

p-Toluolsulfonsaeure-<(E)-4-methoxy-2-methyl-2-butenyl>ester

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 65 percent Chromat. / Mg / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E/Z)-4-Methoxy-2-methyl-2-butenol

(E/Z)-4-Methoxy-2-methyl-2-butenol

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: pyridine / 3 h / Ambient temperature
2: 80 percent / Mg / Li2CuCl4 / tetrahydrofuran
4: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
(E/Z)-4-Methoxy-2-methyl-2-butenylbromid

(E/Z)-4-Methoxy-2-methyl-2-butenylbromid

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Mg / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Essigsaeure-<(E/Z)-4-methoxy-2-methyl-2-butenyl>ester

Essigsaeure-<(E/Z)-4-methoxy-2-methyl-2-butenyl>ester

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 54 percent Chromat. / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Essigsaeure-<(E/Z)-2-methyl-4-(3',4',5',6'-tetrahydro-2'H-pyran-2'-yl)oxy-2-butenyl>ester

Essigsaeure-<(E/Z)-2-methyl-4-(3',4',5',6'-tetrahydro-2'H-pyran-2'-yl)oxy-2-butenyl>ester

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 84 percent Chromat. / Li2CuCl4 / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: 84 percent Chromat. / Li2CuCl4 / tetrahydrofuran
2: 94 percent / pyridinium-p-toluolsulfonate / ethanol / 1.5 h / 55 °C
3: 82 percent / NaH (in oil) / dimethylformamide / Ambient temperature
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Essigsaeure-<(E)-2-methyl-4-(3',4',5',6'-tetrahydro-2'H-pyran-2'-yl)oxy-2-butenyl>ester
66432-56-2

Essigsaeure-<(E)-2-methyl-4-(3',4',5',6'-tetrahydro-2'H-pyran-2'-yl)oxy-2-butenyl>ester

phytomenadione
84-80-0

phytomenadione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: 72 percent / Mg / Li2CuCl4 / tetrahydrofuran / 10 min, -78 deg C then 2 h, 0 deg C then 15 h, r.t.
2: 94 percent / pyridinium-p-toluolsulfonate / ethanol / 1.5 h / 55 °C
3: 82 percent / NaH (in oil) / dimethylformamide / Ambient temperature
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1: 57 percent Chromat. / Mg / CuI / tetrahydrofuran
3: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
Multi-step reaction with 5 steps
1: 57 percent Chromat. / Mg / CuI / tetrahydrofuran
2: 94 percent / pyridinium-p-toluolsulfonate / ethanol / 1.5 h / 55 °C
3: 82 percent / NaH (in oil) / dimethylformamide / Ambient temperature
5: KOH / methanol; hexane; H2O / 2 h / Ambient temperature
View Scheme
6-(trimethylsilyl)hex-5-yn-1-yl 2-cyano-2-diazoacetate
1361382-43-5

6-(trimethylsilyl)hex-5-yn-1-yl 2-cyano-2-diazoacetate

phytomenadione
84-80-0

phytomenadione

C43H63NO4Si

C43H63NO4Si

Conditions
ConditionsYield
With Rh2(esp)2 In dichloromethane at 22℃; for 4h; Inert atmosphere; diastereoselective reaction;84%
phytomenadione
84-80-0

phytomenadione

vitamin K1 2,3 epoxide
25486-55-9, 85954-59-2, 85955-78-8

vitamin K1 2,3 epoxide

Conditions
ConditionsYield
With ethanol; dihydrogen peroxide; sodium carbonate
phytomenadione
84-80-0

phytomenadione

1,4-bis-methanesulfonyloxy-2-methyl-3-((7R,11R)-trans-phytyl)-naphthalene
119877-23-5

1,4-bis-methanesulfonyloxy-2-methyl-3-((7R,11R)-trans-phytyl)-naphthalene

Conditions
ConditionsYield
With pyridine; Lindlar's catalyst Hydrogenation.anschliessendes Behandeln mit Methansulfonylchlorid;
phytomenadione
84-80-0

phytomenadione

1,4-bis-diphenylcarbamoyloxy-2-methyl-3-((7R,11R)-trans-phytyl)-naphthalene

1,4-bis-diphenylcarbamoyloxy-2-methyl-3-((7R,11R)-trans-phytyl)-naphthalene

Conditions
ConditionsYield
Hydrogenation.und Behandeln des Reaktionsprodukts mit Diphenylcarbamoylchlorid;
phytomenadione
84-80-0

phytomenadione

di-O-acetyl-dihydrophylloquinone
604-87-5

di-O-acetyl-dihydrophylloquinone

phytomenadione
84-80-0

phytomenadione

2,5-dimethyl-2RS-(4R,8R,12-trimethyltridec-1-yl)-6-hydroxybenzo[h]chroman
4208-84-8

2,5-dimethyl-2RS-(4R,8R,12-trimethyltridec-1-yl)-6-hydroxybenzo[h]chroman

Conditions
ConditionsYield
With hydrogenchloride; acetic acid; tin(ll) chloride
phytomenadione
84-80-0

phytomenadione

(6R,10R)-6,10,14-trimethylpentadecan-2-one
16825-16-4

(6R,10R)-6,10,14-trimethylpentadecan-2-one

Conditions
ConditionsYield
(i) O3, (ii) aq. AcOH, Zn; Multistep reaction;
Stage #1: phytomenadione In methanol; dichloromethane at -78℃;
Stage #2: With dimethylsulfide In methanol; dichloromethane at -78 - 20℃;
With methanol; potassium hydroxide at 70 - 80℃; for 0.5h;4.9 mg
hydrogenchloride
7647-01-0

hydrogenchloride

phytomenadione
84-80-0

phytomenadione

acetic acid
64-19-7

acetic acid

SnCl2

SnCl2

(Ξ)-6-hydroxy-2.5-dimethyl-2-<(4R:8R)-4.8.12-trimethyl-tridecyl>-3.4-dihydro-2H-benzo<h>chromene

(Ξ)-6-hydroxy-2.5-dimethyl-2-<(4R:8R)-4.8.12-trimethyl-tridecyl>-3.4-dihydro-2H-benzo<h>chromene

ethanol
64-17-5

ethanol

phytomenadione
84-80-0

phytomenadione

dihydrogen peroxide
7722-84-1

dihydrogen peroxide

aqueous Na2CO3

aqueous Na2CO3

(2Ξ:3Ξ)-2.3-epoxy-2-methyl-3-<(7R:11R)-trans-phytyl>-2.3-dihydro-naphthoquinone-(1.4)

(2Ξ:3Ξ)-2.3-epoxy-2-methyl-3-<(7R:11R)-trans-phytyl>-2.3-dihydro-naphthoquinone-(1.4)

Conditions
ConditionsYield
at 70 - 75℃;
methanol
67-56-1

methanol

phytomenadione
84-80-0

phytomenadione

platinum

platinum

2-methyl-3-<(3Ξ.7R:11R)-3.7.11.15-tetramethyl-hexadecyl>-5.6.7.8-tetrahydro-naphthoquinone-(1.4)

2-methyl-3-<(3Ξ.7R:11R)-3.7.11.15-tetramethyl-hexadecyl>-5.6.7.8-tetrahydro-naphthoquinone-(1.4)

Conditions
ConditionsYield
Behandlung des Reaktionsprodukts mit Ag2O und MgSO4 in Aether.Hydrogenation;
phytomenadione
84-80-0

phytomenadione

acetic acid
64-19-7

acetic acid

platinum

platinum

2-methyl-3-<(3Ξ.7R:11R)-3.7.11.15-tetramethyl-hexadecyl>-5.6.7.8-tetrahydro-naphthoquinone-(1.4)

2-methyl-3-<(3Ξ.7R:11R)-3.7.11.15-tetramethyl-hexadecyl>-5.6.7.8-tetrahydro-naphthoquinone-(1.4)

Conditions
ConditionsYield
Behandlung des Reaktionsprodukts mit Ag2O und MgSO4 in Aether.Hydrogenation;
methanol
67-56-1

methanol

phytomenadione
84-80-0

phytomenadione

Raney nickel

Raney nickel

2-methyl-3-<(3Ξ:7R:11R)-3.7.11.15-tetramethyl-hexadecyl>-naphthalenediol-(1.4)

2-methyl-3-<(3Ξ:7R:11R)-3.7.11.15-tetramethyl-hexadecyl>-naphthalenediol-(1.4)

Conditions
ConditionsYield
Hydrogenation;
phytomenadione
84-80-0

phytomenadione

magnesium sulfate
7487-88-9

magnesium sulfate

etheric dihydrophylloquinone

etheric dihydrophylloquinone

Ag2O

Ag2O

Na2SO4

Na2SO4

2-methyl-3-<(7R:11R)-cis-phytyl>-naphthoquinone-(1.4)

2-methyl-3-<(7R:11R)-cis-phytyl>-naphthoquinone-(1.4)

phytomenadione
84-80-0

phytomenadione

etheric dihydrophylloquinone

etheric dihydrophylloquinone

air

air

Na2SO4

Na2SO4

2-methyl-3-<(7R:11R)-cis-phytyl>-naphthoquinone-(1.4)

2-methyl-3-<(7R:11R)-cis-phytyl>-naphthoquinone-(1.4)

sulfuric acid
7664-93-9

sulfuric acid

phytomenadione
84-80-0

phytomenadione

acetic acid
64-19-7

acetic acid

CrO3

CrO3

<1.4-dioxo-3-methyl-naphthyl-(2)>-acetic acid

<1.4-dioxo-3-methyl-naphthyl-(2)>-acetic acid

Conditions
ConditionsYield
at 40℃;
phytomenadione
84-80-0

phytomenadione

2-methyl-3-phytyl-1,4-naphthalenediol
572-96-3

2-methyl-3-phytyl-1,4-naphthalenediol

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol; di-isopropyl ether for 0.166667h;
With sodium dithionite In ethanol; water at 20℃; for 1h;
With sodium chloride; diothiothreitol In aq. buffer at 37℃; pH=8.5; Reagent/catalyst; Temperature; pH-value;
phytomenadione
84-80-0

phytomenadione

C31H46O2

C31H46O2

Conditions
ConditionsYield
In acetonitrile at 20 - 22℃; Flash photolysis;
phytomenadione
84-80-0

phytomenadione

N,N-dimethylglycyloxy-2-methyl-3-phytyl-1-hydroxy-naphthalene

N,N-dimethylglycyloxy-2-methyl-3-phytyl-1-hydroxy-naphthalene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / diisopropyl ether; methanol / 0.17 h
2: dicyclohexylcarbodiimide; pyridine / 24 h / 20 °C
View Scheme
phytomenadione
84-80-0

phytomenadione

N,N-dimethylglycyloxy-2-methyl-3-phytyl-4-hydroxy-naphthalene

N,N-dimethylglycyloxy-2-methyl-3-phytyl-4-hydroxy-naphthalene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / diisopropyl ether; methanol / 0.17 h
2: dicyclohexylcarbodiimide; pyridine / 24 h / 20 °C
View Scheme
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