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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Manufacturer supply 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester CAS 847818-74-0 with attractive price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceuti

Manufacturer supply 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester CAS 847818-74-0 with attractive price

Cas:847818-74-0

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

1-methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 847818-74-0 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester Manufacturer

Cas:847818-74-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/149.html Product Name 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester CAS No.

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:1 Gram

FOB Price: $56.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

1-Methyl-1h-Pyrazole-5-Boronic Acid Pinacol Ester CAS 847818-74-0

Cas:847818-74-0

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 847818-74-0 with best price

Cas:847818-74-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester 847818-74-0

Cas:847818-74-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;1-Methyl-1H-pyrazole-3-boronic acid pinacol ester CAS: 847818-74-0 MF: C10H17BN2O2 MW: 208.07 EINECS: 1-Methyl-1H-p

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:847818-74-0

Cas:847818-74-0

Min.Order:0

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Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1-Methyl-1H-Pyrazole-5-Boronic Acid Pinacol Ester

Cas:847818-74-0

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:As

1-METHYL-1H-PYRAZOLE-5-BORONIC ACIDPINACOL ESTER

Cas:847818-74-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to provide excellence

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

1-METHYL-1H-PYRAZOLE-5-BORONIC ACID PINACOL ESTER

Cas:847818-74-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Cas:847818-74-0

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:0 Metric Ton

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Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:0

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Type:Lab/Research institutions

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:100 Gram

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Type:Other

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Shanghai Send Pharmaceutical Technology Co., Ltd.

low price high quality high purity good sevice stock Appearance:white Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical intermediat

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester 847818-74-0

Cas:847818-74-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester ,98%

Cas:847818-74-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

1-METHYL-1H-PYRAZOLE-5-BORONIC ACID PINACOL ESTER

Cas:847818-74-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:0

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Type:Other

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:0

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Type:Lab/Research institutions

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Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Cas:847818-74-0

Min.Order:0

Negotiable

Type:Trading Company

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester cas no. 847818-74-0 98%

Cas:847818-74-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester

Cas:847818-74-0

Min.Order:0

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Synthetic route

1-methyl-1H-pyrazole
930-36-9

1-methyl-1H-pyrazole

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane With C26H50CoN4O2 at 20℃; for 0.0833333h; Inert atmosphere; Glovebox;
Stage #2: 1-methyl-1H-pyrazole at 80℃; for 48h; Inert atmosphere; Sealed tube;
90%
2,3-dimethyl-2,3-butane diol
76-09-5

2,3-dimethyl-2,3-butane diol

(1-methyl-1H-pyrazol-5-yl)boronic acid
720702-41-0

(1-methyl-1H-pyrazol-5-yl)boronic acid

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With 4 A molecular sieve In tetrahydrofuran at 20℃; for 2h;84%
In tetrahydrofuran at 20℃; for 48h; Molecular sieve;67%
1-methyl-1H-pyrazole
930-36-9

1-methyl-1H-pyrazole

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
61676-62-8

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 1-methyl-1H-pyrazole With n-butyllithium In tetrahydrofuran at 0 - 20℃; for 1h;
Stage #2: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran at -78 - 0℃; for 1.25h;
Stage #3: With ammonium chloride In tetrahydrofuran
77%
Stage #1: 1-methyl-1H-pyrazole With n-butyllithium In tetrahydrofuran at 0 - 20℃;
Stage #2: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran at -78℃;
77%
Stage #1: 1-methyl-1H-pyrazole With n-butyllithium In tetrahydrofuran at 0 - 20℃; for 1h;
Stage #2: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran at -78 - 0℃; for 1.25h;
77%
Triisopropyl borate
5419-55-6

Triisopropyl borate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 1-methyl-1H-pyrazole With n-butyllithium In tetrahydrofuran; hexanes at -78 - 20℃; for 1h;
Stage #2: Triisopropyl borate In tetrahydrofuran; hexanes for 1h;
Stage #3: With hydrogenchloride; water In tetrahydrofuran; hexanes
51%
3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
844501-71-9, 1086111-17-2

3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

methyl iodide
74-88-4

methyl iodide

A

1-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
1020174-04-2

1-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

B

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃; for 70h;
1-methyl-1H-pyrazole
930-36-9

1-methyl-1H-pyrazole

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

A

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

B

1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
761446-44-0

1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer In hexane at 20℃; Glovebox; Inert atmosphere;
Stage #2: With 4,4'-di-tert-butyl-2,2'-bipyridine In hexane at 20℃; Glovebox; Inert atmosphere;
Stage #3: 1-methyl-1H-pyrazole In hexane at 20℃; for 5h; Reagent/catalyst; Solvent; Glovebox; Inert atmosphere; Overall yield = 67 percent; regioselective reaction;
methyl 4-bromo-5-ethyl-2-thiophenecarboxylate
1047645-89-5

methyl 4-bromo-5-ethyl-2-thiophenecarboxylate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

methyl 5-ethyl-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylate
1047645-90-8

methyl 5-ethyl-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylate

Conditions
ConditionsYield
With potassium carbonate; bis(tri-t-butylphosphine)palladium(0) at 80℃; for 1h;100%
1,1-dimethylethyl (2-{[(5-bromo-3-thienyl)carbonyl]amino}-2-phenylethyl)carbamate
1044851-72-0

1,1-dimethylethyl (2-{[(5-bromo-3-thienyl)carbonyl]amino}-2-phenylethyl)carbamate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

1,1-dimethylethyl [2-({[5-(1-methyl-1H-pyrazol-5-yl)-3-thienyl]carbonyl}amino)-2-phenylethyl]carbamate
1044851-74-2

1,1-dimethylethyl [2-({[5-(1-methyl-1H-pyrazol-5-yl)-3-thienyl]carbonyl}amino)-2-phenylethyl]carbamate

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 80℃; for 17h; Suzuki Coupling;100%
2-bromothiophene-4-carboxylic acid
100523-84-0

2-bromothiophene-4-carboxylic acid

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

5-(2-methyl-2H-pyrazol-3-yl)-thiophene-3-carboxylic acid
1044851-90-2

5-(2-methyl-2H-pyrazol-3-yl)-thiophene-3-carboxylic acid

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 80℃; for 12 - 17h; Suzuki Coupling;100%
N-(2-bromo-4-(trifluoromethyl)phenyl)acetamide
175135-49-6

N-(2-bromo-4-(trifluoromethyl)phenyl)acetamide

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

N-(2-(1-methyl-1H-pyrazol-5-yl)-4-(trifluoromethyl)phenyl)acetamide

N-(2-(1-methyl-1H-pyrazol-5-yl)-4-(trifluoromethyl)phenyl)acetamide

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water for 1h; Suzuki Coupling; Reflux;100%
With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water for 1h; Reflux;100%
2-[(3R)-3-methylmorpholin-4-yl]-8-[1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl]-1,7-naphthyridin-4-yl trifluoromethanesulfonate

2-[(3R)-3-methylmorpholin-4-yl]-8-[1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl]-1,7-naphthyridin-4-yl trifluoromethanesulfonate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

(3R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine

(3R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In water at 110℃; for 3h; Inert atmosphere;100%
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In 1,2-dimethoxyethane; water at 130℃; for 0.333333h; Suzuki Coupling; Microwave irradiation;
methyl 4-bromo-5-propyl-2-thiophenecarboxylate
1047628-66-9

methyl 4-bromo-5-propyl-2-thiophenecarboxylate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

methyl 4-(1-methyl-1H-pyrazol-5-yl)-5-propyl-2-thiophenecarboxylate
1047628-67-0

methyl 4-(1-methyl-1H-pyrazol-5-yl)-5-propyl-2-thiophenecarboxylate

Conditions
ConditionsYield
With potassium carbonate; bis(tri-t-butylphosphine)palladium(0) at 80℃; for 1h;99%
1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

4-chloro-1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1H-pyrazole
1430057-83-2

4-chloro-1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With N-chloro-succinimide; 2,4,6-trimethylaniline In dichloromethane at 20℃; for 24h; Inert atmosphere;99%
With 2-chloro-1,3-bis(methoxycarbonyl)guanidine In acetonitrile at 20℃; for 12h; Reagent/catalyst; regioselective reaction;98%
With N-chloro-succinimide; 2,2,6,6-tetramethylpiperidin-1-oxoammonium trifluoromethanesulfonate In chloroform at 25℃; for 12h; Reagent/catalyst; Schlenk technique;96%
tert-butyl (2-(4-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)ethyl)carbamate

tert-butyl (2-(4-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)ethyl)carbamate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

tert-butyl (2-(4-(1-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)ethyl)carbamate

tert-butyl (2-(4-(1-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)ethyl)carbamate

Conditions
ConditionsYield
With methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II) In tetrahydrofuran; ethanol; water at 50℃; for 12h; Inert atmosphere;99%
tert-butyl 1-(4-(2-chloro-7-phenylfuro[2,3-b]pyrazin-6-yl)phenyl)cyclobutylcarbamate
1301612-83-8

tert-butyl 1-(4-(2-chloro-7-phenylfuro[2,3-b]pyrazin-6-yl)phenyl)cyclobutylcarbamate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

tert-butyl 1-(4-(2-(1-methyl-1H-pyrazol-5-yl)-7-phenylfuro[2,3-b]pyrazin-6-yl)phenyl)cyclobutylcarbamate
1301612-87-2

tert-butyl 1-(4-(2-(1-methyl-1H-pyrazol-5-yl)-7-phenylfuro[2,3-b]pyrazin-6-yl)phenyl)cyclobutylcarbamate

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In water; N,N-dimethyl-formamide at 120℃; for 0.333333h; Microwave irradiation; Inert atmosphere; Sealed tube;98%
2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

2-chloro-5-fluoro-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine

2-chloro-5-fluoro-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate In tetrahydrofuran; water Reflux;98%
PU-DZ13

PU-DZ13

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

2-fluoro-9-(2-(isobutylamino)ethyl)-8-((6-(1-methyl-1H-pyrazol-5-yl)benzo[d][1,3]dioxol-5-yl)methyl)-9H-purin-6-amine
1289544-05-3

2-fluoro-9-(2-(isobutylamino)ethyl)-8-((6-(1-methyl-1H-pyrazol-5-yl)benzo[d][1,3]dioxol-5-yl)methyl)-9H-purin-6-amine

Conditions
ConditionsYield
With sodium hydrogencarbonate; bis-triphenylphosphine-palladium(II) chloride In water; N,N-dimethyl-formamide at 90℃; for 2h; Suzuki Coupling; Inert atmosphere;97%
4-Bromo-3-methylbenzoic acid methyl ester
148547-19-7

4-Bromo-3-methylbenzoic acid methyl ester

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

methyl 3-methyl-4-(1-methyl-1H-pyrazol-5-yl)benzoate

methyl 3-methyl-4-(1-methyl-1H-pyrazol-5-yl)benzoate

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 100℃; for 10h; Inert atmosphere;97%
1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

4-bromo-1-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
942070-88-4

4-bromo-1-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With N-Bromosuccinimide; 2,4,6-trimethylaniline In dichloromethane at -40 - 0℃; for 24h; Inert atmosphere; regioselective reaction;96%
2,6-Dichloropyrimidine
3934-20-1

2,6-Dichloropyrimidine

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

2-chloro-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine

2-chloro-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine

Conditions
ConditionsYield
With palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium carbonate In 1,4-dioxane; water at 120℃; for 2h;96%
5-bromo-1-(4-fluorophenyl)-3-(1-methylpiperidin-4-yl)-1H-indole
1415089-66-5

5-bromo-1-(4-fluorophenyl)-3-(1-methylpiperidin-4-yl)-1H-indole

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

C24H25FN4
1415089-44-9

C24H25FN4

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; toluene at 100℃; Suzuki-Miyaura Coupling; Inert atmosphere;95%
4-methoxycarbonylphenyl bromide
619-42-1

4-methoxycarbonylphenyl bromide

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

methyl 4-(1-methyl-1H-pyrazol-5-yl)benzoate
179057-12-6

methyl 4-(1-methyl-1H-pyrazol-5-yl)benzoate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium phosphate tribasic trihydrate In N,N-dimethyl-formamide at 0 - 120℃; Suzuki Coupling; Inert atmosphere;95%
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 100℃; for 10h; Inert atmosphere;89%
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 0 - 100℃; for 10h; Inert atmosphere;89%
With tetrakis(triphenylphosphine) palladium(0); potassium phosphate tribasic trihydrate In N,N-dimethyl-formamide at 90℃; Suzuki Coupling; Inert atmosphere;85%
4-fluoro-3-iodo-naphthalene-1-carbonitrile

4-fluoro-3-iodo-naphthalene-1-carbonitrile

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

4-fluoro-3-(2-methylpyrazol-3-yl)naphthalene-1-carbonitrile

4-fluoro-3-(2-methylpyrazol-3-yl)naphthalene-1-carbonitrile

Conditions
ConditionsYield
With potassium phosphate; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II) In 1,4-dioxane; water at 80℃; for 18h; Inert atmosphere;95%
4-bromo-2-fluoro-1-(methylsulfonyl)benzene
648904-84-1

4-bromo-2-fluoro-1-(methylsulfonyl)benzene

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

5-(3-fluoro-4-methanesulfonylphenyl)-1-methyl-1H-pyrazole

5-(3-fluoro-4-methanesulfonylphenyl)-1-methyl-1H-pyrazole

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate In 1,4-dioxane; water at 100℃; Inert atmosphere;94%
5-bromo-3-methylpyridine-2-carboxylic acid methyl ester
213771-32-5

5-bromo-3-methylpyridine-2-carboxylic acid methyl ester

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

methyl 3-methyl-5-(1-methyl-1H-pyrazol-5-yl)picolinate

methyl 3-methyl-5-(1-methyl-1H-pyrazol-5-yl)picolinate

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 100℃; for 10h; Inert atmosphere;94%
methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-6-carboxylate

methyl 2-bromo-[1,2,4]triazolo[1,5-a]pyridine-6-carboxylate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

methyl 2-(1-methyl-1H-pyrazol-5-yl)[1,2,4]triazolo[1,5-a]pyridine-6-carboxylate

methyl 2-(1-methyl-1H-pyrazol-5-yl)[1,2,4]triazolo[1,5-a]pyridine-6-carboxylate

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate In 1,4-dioxane; water at 60℃; for 2h;94%
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate In 1,4-dioxane; dichloromethane; water at 60℃; for 2h; Suzuki Coupling;94%
N-[1-(4-chloro-phthalazin-1-yl)-piperidin-4-yl]-4-fluoro-N-methyl-2-trifluoromethyl-benzamide

N-[1-(4-chloro-phthalazin-1-yl)-piperidin-4-yl]-4-fluoro-N-methyl-2-trifluoromethyl-benzamide

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

4-fluoro-N-methyl-N-{1-[4-(1-methyl-1H-pyrazole-5-yl)phthalazin-1-yl]piperidin-4-yl}-2-(trifluoromethyl)benzamide
1258861-20-9

4-fluoro-N-methyl-N-{1-[4-(1-methyl-1H-pyrazole-5-yl)phthalazin-1-yl]piperidin-4-yl}-2-(trifluoromethyl)benzamide

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In ethanol; water; toluene at 74℃; for 12h; Suzuki Coupling; Inert atmosphere;92%
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In ethanol; water; toluene at 74℃; for 12h; Suzuki Coupling; Inert atmosphere;92%
C6H4BrFO3S

C6H4BrFO3S

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

C10H9FN2O3S

C10H9FN2O3S

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium phosphate tribasic trihydrate In N,N-dimethyl-formamide at 90℃; Inert atmosphere;92%
(6-cyano-7-quinolyl)trifluoromethanesulfonate

(6-cyano-7-quinolyl)trifluoromethanesulfonate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

7-(2-methylpyrazol-3-yl)quinoline-6-carbonitrile

7-(2-methylpyrazol-3-yl)quinoline-6-carbonitrile

Conditions
ConditionsYield
With dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); sodium hydrogencarbonate In 1,4-dioxane; water at 80℃; for 1h; Inert atmosphere;92%
5-bromo-N-cyclopentyl-N-(2,4-dimethoxybenzyl)-2-methoxybenzenesulfonamide

5-bromo-N-cyclopentyl-N-(2,4-dimethoxybenzyl)-2-methoxybenzenesulfonamide

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

N-cyclopentyl-N-(2,4-dimethoxybenzyl)-2-methoxy-5-(1-methyl-1H-pyrazol-5-yl)benzenesulfonamide

N-cyclopentyl-N-(2,4-dimethoxybenzyl)-2-methoxy-5-(1-methyl-1H-pyrazol-5-yl)benzenesulfonamide

Conditions
ConditionsYield
With dichloro-[1,3-bis(2,6-diisopropylpenyl)-2-imidazolidinyliden]-(3-chloropyridyl)palladium(II); caesium carbonate In 1,4-dioxane; water; N,N-dimethyl-formamide at 90℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere; Microwave irradiation;91%
2-chloro-N-(4-(chlorodifluoromethoxy)phenyl)-[3,3‘-bipyridine]-5-carboxamide

2-chloro-N-(4-(chlorodifluoromethoxy)phenyl)-[3,3‘-bipyridine]-5-carboxamide

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

N-(4-(chlorodifluoromethoxy)phenyl)-2-(1-methyl-1H-pyrazol-5-yl)-[3,3‘-bipyridine]-5-carboxamide

N-(4-(chlorodifluoromethoxy)phenyl)-2-(1-methyl-1H-pyrazol-5-yl)-[3,3‘-bipyridine]-5-carboxamide

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In 1,4-dioxane; water at 100℃; Concentration; Inert atmosphere;91%
tert-butyl 4-((7-(3-bromophenyl)-6-chloro-4-oxo-4, 7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)methyl)-4-hydroxypiperidine-1-carboxylate

tert-butyl 4-((7-(3-bromophenyl)-6-chloro-4-oxo-4, 7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)methyl)-4-hydroxypiperidine-1-carboxylate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

tert-butyl 4-((6-chloro-7-(3-(1-methyl-1H-pyrazol-5-yl)phenyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)methyl)-4-hydroxypiperidine-1-carboxylate

tert-butyl 4-((6-chloro-7-(3-(1-methyl-1H-pyrazol-5-yl)phenyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)methyl)-4-hydroxypiperidine-1-carboxylate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,4-dioxane; water at 140℃; for 0.5h; Suzuki Coupling; Inert atmosphere; Microwave irradiation; Sealed tube;91%
N-(1-(6-chloro-4,5-dimethyl-3-pyridazinyl)-4-piperidinyl)-4-fluoro-N-methyl-2-(trifluoromethyl)benzamide

N-(1-(6-chloro-4,5-dimethyl-3-pyridazinyl)-4-piperidinyl)-4-fluoro-N-methyl-2-(trifluoromethyl)benzamide

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

N-(1-(4,5-dimethyl-6-(1-methyl-1H-pyrazol-5-yl)pyridazin-3-yl)piperidin-4-yl)-4-fluoro-N-methyl-2-(trifluoromethyl)benzamide

N-(1-(4,5-dimethyl-6-(1-methyl-1H-pyrazol-5-yl)pyridazin-3-yl)piperidin-4-yl)-4-fluoro-N-methyl-2-(trifluoromethyl)benzamide

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In methanol; water; toluene at 74℃; for 12h; Inert atmosphere;89%
tert-butyl (R)-4-((S)-10-((4-chloro-2-oxopyridin-1(2H)-yl)methyl)-10-hydroxy-7-azaspiro[4.5]decane-7-carbonyl)-3-phenylpiperazine-1-carboxylate

tert-butyl (R)-4-((S)-10-((4-chloro-2-oxopyridin-1(2H)-yl)methyl)-10-hydroxy-7-azaspiro[4.5]decane-7-carbonyl)-3-phenylpiperazine-1-carboxylate

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

tert-butyl (R)-4-((S)-10-hydroxy-10-((4-(1-methyl-1H-pyrazol-5-yl)-2-oxopyridin-1(2H)-yl)methyl)-7-azaspiro[4.5]decane-7-carbonyl)-3-phenylpiperazine-1-carboxylate

tert-butyl (R)-4-((S)-10-hydroxy-10-((4-(1-methyl-1H-pyrazol-5-yl)-2-oxopyridin-1(2H)-yl)methyl)-7-azaspiro[4.5]decane-7-carbonyl)-3-phenylpiperazine-1-carboxylate

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate In 1,4-dioxane; water at 120℃; for 0.5h; Suzuki Coupling; Inert atmosphere; Sealed tube; Microwave irradiation;89%
6-bromo-3-cyclopropoxypicolinonitrile

6-bromo-3-cyclopropoxypicolinonitrile

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

3-cyclopropoxy-6-(1-methyl-1H-pyrazol-5-yl)picolinonitrile

3-cyclopropoxy-6-(1-methyl-1H-pyrazol-5-yl)picolinonitrile

Conditions
ConditionsYield
With dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); sodium carbonate In 1,4-dioxane; water at 25 - 80℃; for 2h;89%

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