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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Amino-4-nitrophenol Manufacturer/High quality/Best price/In stock

Cas:99-57-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Para Nitrophenol supplier in China

Cas:99-57-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-amino-4-nitrophenol

Cas:99-57-0

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

2-Amino-4-nitrophenol Basic information Product Name: 2-Amino-4-nitrophenol Synonyms: 2-HYDROXY-5-NITROANILINE;2-AMINO-4-NITROPHENOL;4-NAP;4-NITRO-2-AMINOPHENOL;3-AMINO-4-HYDROXYNITROBEN

TIANFU-CHEM CAS:99-57-0 2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

CAS Number 99-57-0 Product Name 2-amino-4-nitrophenol Synonyms 2-amino-4-nitrophenol; 2-amino-4-nitrophenolate; 3-amino-4-hydrox

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Nitro-2-aminophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Para Nitrophenol

Cas:99-57-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

2-Hydroxy-5-Nitroaniline

Cas:99-57-0

Min.Order:0

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers153.Safe and fa

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd a comprehensive enterprise, is located in High-Tech Science Park,Changsha,Chia . Specializing in R&D, manufacture and marketing, we provide a wide range of products and the most professional services to meet the

Menadione

Cas:99-57-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Para Nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2-AMino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

High quality CAS 99-57-0 with best price

Cas:99-57-0

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

2-Amino-4-nitrophenol 99-57-0 Application:2-Amino-4-nitrophenol 99-57-0

2-Amino-4-nitrophenol 99-57-0

Cas:99-57-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Fandachem Co.,Ltd

2-Amino-4-nitrophenol cas 99-57-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2-Amino-4-nitrophenol cas 99-57-0

Cas:99-57-0

Min.Order:0

Negotiable

Type:Other

inquiry

SAGECHEM LIMITED

2-AMINO-4-NITRO PHENOL

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

2-Amino-4-nitrophenol 99-57-0Appearance:off-white Storage:stored in a cool, dry and ventilated place Package:as per buyer's request Application:Organic Chemicals Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By ai

2-Amino-4-nitrophenol 99-57-0

Cas:99-57-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

2-Amino-4-nitrophenol 99-57-0

Cas:99-57-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

AstaTech ( Chengdu) BioPharmaceutical Corp.

Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Other

inquiry

Research Organics, Inc.

2-Amino-4-nitrophenol

Cas:99-57-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With hydrazine hydrate at 90℃; for 18h;98%
With hydrazine hydrate In water at 110℃; Sealed tube; Green chemistry;95%
With hydrazine hydrate In isopropyl alcohol at 110℃; for 0.25h; Catalytic behavior; Sealed tube; chemoselective reaction;94%
sodium 2,4-dinitrophenoxide
1011-73-0

sodium 2,4-dinitrophenoxide

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen at 70℃; under 4500.45 Torr; for 2h; Temperature; Pressure; Time; Autoclave;97.1%
C6H7BN2O4
1604034-83-4

C6H7BN2O4

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With iron(III) oxide; oxygen In tetrahydrofuran at 20℃; Irradiation;95%
2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

A

4-amino-2-nitrophenol
119-34-6

4-amino-2-nitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h;A 7%
B 92%
With hydrogen; iron; acetic acid; palladium dichloride In ethanol at 20 - 25℃; under 258.6 - 2327.2 Torr;A n/a
B 79%
With sodium hydroxide; sodium disulfide
With sodium sulfide; 5-hydroxynaphtho-1,4-quinone; water In methanol; phosphate buffer for 12h; pH=2.5; Reduction;
2-amino-phenol
95-55-6

2-amino-phenol

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With nickel ammonium sulfate; nitric acid In chloroform; water at 20℃; for 3h;92%
Multi-step reaction with 2 steps
2: HNO3+H2SO4 / <0 / beim Kochen des Reaktionsprodukts mit Salzsaeure
View Scheme
With sulfuric acid; nitric acid In chloroform at 8 - 12℃; Solvent; Temperature; Large scale;830 kg
2-azido-4-nitrophenol
33354-58-4

2-azido-4-nitrophenol

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With ammonium hydroxide at 90℃; for 2.41667h;78%
1-phenyl-2-(piperidin-1-yl)ethanone O-(2,4-dinitrophenyl)oxime

1-phenyl-2-(piperidin-1-yl)ethanone O-(2,4-dinitrophenyl)oxime

A

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

C

2-Phenyl-5,6,7,8-tetrahydro-imidazo<1,2-a>pyridin
3649-46-5

2-Phenyl-5,6,7,8-tetrahydro-imidazo<1,2-a>pyridin

Conditions
ConditionsYield
In dimethyl sulfoxide at 25℃; for 5h; Inert atmosphere; Schlenk technique; Sealed tube; Irradiation;A 33%
B 22%
C 75%
4-Nitrophenylene-1,2-diamine
99-56-9

4-Nitrophenylene-1,2-diamine

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With water; sodium hydroxide at 100℃; for 4h;65%
2-amino-phenol
95-55-6

2-amino-phenol

A

2-amino-6-nitrophenol
603-87-2

2-amino-6-nitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With sulfuric acid; aminosulfonic acid; nitric acid at 0℃; for 0.5h;A 26%
B 44%
6-fluoro-3-nitroaniline
369-36-8

6-fluoro-3-nitroaniline

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With sodium hydroxide for 72h; Heating;30%
2-methyl-1,3-benzoxazole
95-21-6

2-methyl-1,3-benzoxazole

A

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

B

2-Amino-5-nitrophenol
121-88-0

2-Amino-5-nitrophenol

Conditions
ConditionsYield
With sulfuric acid; nitric acid beim Kochen des Reaktionsprodukts mit Salzsaeure;
3-nitrophenyl azide
1516-59-2

3-nitrophenyl azide

A

4-amino-2-nitrophenol
119-34-6

4-amino-2-nitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With sulfuric acid
2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

hydrogen sulfide
7783-06-4

hydrogen sulfide

ammonia
7664-41-7

ammonia

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

alkaline aqueous Na2S

alkaline aqueous Na2S

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

water
7732-18-5

water

hydrogen

hydrogen

nickel

nickel

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

water
7732-18-5

water

sulfur dioxide

sulfur dioxide

iron turnings

iron turnings

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
at 80 - 90℃;
2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

vanadium compound

vanadium compound

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
bei der elektrolytischen Reduktion;
m-nitro-diazobenzeneimide

m-nitro-diazobenzeneimide

A

4-amino-2-nitrophenol
119-34-6

4-amino-2-nitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
With sulfuric acid
sulfuric acid
7664-93-9

sulfuric acid

3-nitrophenyl azide
1516-59-2

3-nitrophenyl azide

A

4-amino-2-nitrophenol
119-34-6

4-amino-2-nitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

para-methoxynitrobenzene
100-17-4

para-methoxynitrobenzene

A

4-methoxy-aniline
104-94-9

4-methoxy-aniline

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

C

3-amino-4-methoxynitrobenzene
99-59-2

3-amino-4-methoxynitrobenzene

Conditions
ConditionsYield
With 3,5-dinitrobenzoic acid; ammonia In water-d2; acetonitrile UV-irradiation;
2-hydroxynitrobenzene
88-75-5

2-hydroxynitrobenzene

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Na2S2O4; NaOH-solution / <30
3: HNO3+H2SO4 / <0 / beim Kochen des Reaktionsprodukts mit Salzsaeure
View Scheme
2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

A

4-nitro-phenol
100-02-7

4-nitro-phenol

B

1,2-dihydroxy-4-nitrobenzene
3316-09-4

1,2-dihydroxy-4-nitrobenzene

C

C6H4N2O4

C6H4N2O4

D

C12H8N4O7

C12H8N4O7

E

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
In isopropyl alcohol Mechanism; Irradiation;
1-chloro-2,4-dinitro-benzene
97-00-7

1-chloro-2,4-dinitro-benzene

A

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: triethylamine / acetone / 25 °C / Inert atmosphere
2: hydrazine hydrate / methanol; dichloromethane / 8 h / 0 °C / Inert atmosphere
3: hydrogenchloride / ethanol / 25 °C / Inert atmosphere
4: sodium carbonate / dichloromethane / 2 h / 25 °C / Inert atmosphere
5: dimethyl sulfoxide / 5 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube; Irradiation
View Scheme
2-(2,4-dinitrophenoxy)-1H-isoindole-1,3(2H)-dione
60506-35-6

2-(2,4-dinitrophenoxy)-1H-isoindole-1,3(2H)-dione

A

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrazine hydrate / methanol; dichloromethane / 8 h / 0 °C / Inert atmosphere
2: hydrogenchloride / ethanol / 25 °C / Inert atmosphere
3: sodium carbonate / dichloromethane / 2 h / 25 °C / Inert atmosphere
4: dimethyl sulfoxide / 5 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube; Irradiation
View Scheme
O-(2,4-dinitrophenyl)hydroxylamine
17508-17-7

O-(2,4-dinitrophenyl)hydroxylamine

A

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / ethanol / 25 °C / Inert atmosphere
2: sodium carbonate / dichloromethane / 2 h / 25 °C / Inert atmosphere
3: dimethyl sulfoxide / 5 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube; Irradiation
View Scheme
2-bromo-1-phenylethanone O-(2,4-dinitro-phenyl)oxime

2-bromo-1-phenylethanone O-(2,4-dinitro-phenyl)oxime

A

2,4-Dinitrophenol
51-28-5

2,4-Dinitrophenol

B

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

C

2-Phenyl-5,6,7,8-tetrahydro-imidazo<1,2-a>pyridin
3649-46-5

2-Phenyl-5,6,7,8-tetrahydro-imidazo<1,2-a>pyridin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium carbonate / dichloromethane / 2 h / 25 °C / Inert atmosphere
2: dimethyl sulfoxide / 5 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube; Irradiation
View Scheme
2-amino-6-nitrophenol
603-87-2

2-amino-6-nitrophenol

A

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

B

2-Amino-5-nitrophenol
121-88-0

2-Amino-5-nitrophenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: triethylamine / 1,2-dichloro-ethane / 65 - 75 °C / Large scale
2.1: hydrogen; platinum on activated charcoal / 1,2-dichloro-ethane / 55 - 65 °C / 4500.45 - 6000.6 Torr / Large scale
3.1: sulfuric acid; sodium nitrite; copper(II) sulfate / isopropyl alcohol; ethyl acetate / Heating; Large scale
4.1: sulfuric acid; nitric acid / dichloromethane / 35 - 45 °C / Large scale
4.2: 100 - 105 °C / 1125.11 - 1875.19 Torr / pH 8 / Large scale
View Scheme
2,6-dinitrophenol
573-56-8

2,6-dinitrophenol

A

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

B

2-Amino-5-nitrophenol
121-88-0

2-Amino-5-nitrophenol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: palladium on activated charcoal; hydrogen / 1,2-dichloro-ethane / 35 - 40 °C / 1500.15 - 4500.45 Torr / Large scale
2.1: triethylamine / 1,2-dichloro-ethane / 65 - 75 °C / Large scale
3.1: hydrogen; platinum on activated charcoal / 1,2-dichloro-ethane / 55 - 65 °C / 4500.45 - 6000.6 Torr / Large scale
4.1: sulfuric acid; sodium nitrite; copper(II) sulfate / isopropyl alcohol; ethyl acetate / Heating; Large scale
5.1: sulfuric acid; nitric acid / dichloromethane / 35 - 45 °C / Large scale
5.2: 100 - 105 °C / 1125.11 - 1875.19 Torr / pH 8 / Large scale
View Scheme
4-nitrobenzo[d]oxazol-2(3H)-one
28955-71-7

4-nitrobenzo[d]oxazol-2(3H)-one

A

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

B

2-Amino-5-nitrophenol
121-88-0

2-Amino-5-nitrophenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: hydrogen; platinum on activated charcoal / 1,2-dichloro-ethane / 55 - 65 °C / 4500.45 - 6000.6 Torr / Large scale
2.1: sulfuric acid; sodium nitrite; copper(II) sulfate / isopropyl alcohol; ethyl acetate / Heating; Large scale
3.1: sulfuric acid; nitric acid / dichloromethane / 35 - 45 °C / Large scale
3.2: 100 - 105 °C / 1125.11 - 1875.19 Torr / pH 8 / Large scale
View Scheme
chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

6-nitro-4H-benzo[1,4]oxazin-3-one
81721-87-1

6-nitro-4H-benzo[1,4]oxazin-3-one

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;100%
With sodium hydrogencarbonate In water; 4-methyl-2-pentanone at 0℃; Heating / reflux;100%
Stage #1: 2-hydroxy-5-nitroaniline With sodium hydrogencarbonate In water at 0℃; for 0.5h;
Stage #2: chloroacetyl chloride In water Reflux;
95%
2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

4-methoxyphenyl-acetic chloride
4693-91-8

4-methoxyphenyl-acetic chloride

N-(2-hydroxy-5-nitro-phenyl)-2-(4-methoxy-phenyl)-acetamide

N-(2-hydroxy-5-nitro-phenyl)-2-(4-methoxy-phenyl)-acetamide

Conditions
ConditionsYield
With pyridine In tetrahydrofuran at 0 - 20℃; for 2h;100%
chloranil
118-75-2

chloranil

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

8-nitro-1,2,4-trichloro-3H-phenoxazin-3-one
32624-06-9

8-nitro-1,2,4-trichloro-3H-phenoxazin-3-one

Conditions
ConditionsYield
With sodium acetate In ethanol for 24h;99%
With sodium acetate In ethanol
With ethanol; sodium acetate at 25℃;
1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

5-nitro-3H-benzooxazol-2-one
3889-13-2

5-nitro-3H-benzooxazol-2-one

Conditions
ConditionsYield
In tetrahydrofuran for 2h; Reflux;99%
In tetrahydrofuran for 3h; Reflux;99%
In dichloromethane at 20℃; for 24h; Inert atmosphere;96%
trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

N-(2'-hydroxy-5'-nitrophenyl)trifluoroacetamide
170363-62-9

N-(2'-hydroxy-5'-nitrophenyl)trifluoroacetamide

Conditions
ConditionsYield
With pyridine In tetrahydrofuran at 20℃; for 16h;99%
furfural
98-01-1

furfural

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2-(2'-furylmethyl)amino-4-nitrophenol
890657-56-4

2-(2'-furylmethyl)amino-4-nitrophenol

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride In tetrahydrofuran at 20℃;98%
2,5-hexanedione
110-13-4

2,5-hexanedione

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

1-(2’-hydroxy-5’-nitrophenyl)-2,5-dimethyl-1H-pyrrole

1-(2’-hydroxy-5’-nitrophenyl)-2,5-dimethyl-1H-pyrrole

Conditions
ConditionsYield
With Cl(1-)*C5H14NO(1+)*3ZnCl2 In neat (no solvent) for 0.166667h; Paal-Knorr Pyrrole Synthesis; Sealed tube; Sonication; Green chemistry;98%
With MIL-53(Al) In neat (no solvent) at 80℃; for 0.25h; Paal-Knorr Pyrrole Synthesis; Sonication;98%
With nano-Fe3O4 immoblized lewis acidic ionic liquid In neat (no solvent) at 20℃; for 0.75h; Paal-Knorr Pyrrole Synthesis; Sonication;63%
1,12-dodecanedioyl dichloride
4834-98-4

1,12-dodecanedioyl dichloride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

C24H30N4O8

C24H30N4O8

Conditions
ConditionsYield
With lithium chloride In 1-methyl-pyrrolidin-2-one; water; isopropyl alcohol at 20℃; for 1h; Inert atmosphere; Cooling with ice;98%
benzaldehyde
100-52-7

benzaldehyde

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2-hydroxy-5-nitro-N-benzylideneaniline
3230-49-7

2-hydroxy-5-nitro-N-benzylideneaniline

Conditions
ConditionsYield
In methanol for 1h;97.2%
In water at 140℃; for 3.5h; Temperature; High pressure;64.5%
formic acid
64-18-6

formic acid

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

N-(2-hydroxy-5-nitrophenyl)formamide
70886-35-0

N-(2-hydroxy-5-nitrophenyl)formamide

Conditions
ConditionsYield
Stage #1: formic acid With acetic anhydride at 70℃; for 2h;
Stage #2: 2-hydroxy-5-nitroaniline In tetrahydrofuran at 20℃; for 3h;
97%
Stage #1: formic acid With acetic anhydride at 70℃; for 2h;
Stage #2: 2-hydroxy-5-nitroaniline In tetrahydrofuran at 20℃; for 3h;
97%
With sodium formate for 2.5h; Heating;94%
With pyridine; acetic anhydride at 20℃; for 18h;
butyryl chloride
141-75-3

butyryl chloride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

N-(2'-hydroxy-5'-nitrophenyl)butyramide
199929-62-9

N-(2'-hydroxy-5'-nitrophenyl)butyramide

Conditions
ConditionsYield
With pyridine In tetrahydrofuran Heating;97%
With pyridine In tetrahydrofuran for 60h; Heating;97%
With 4-methyl-morpholine In dichloromethane at 0℃; for 0.5h;72%
potassium ethyl xanthogenate
140-89-6

potassium ethyl xanthogenate

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2-mercapto-5-nitrobenzo[d]oxazole
22876-21-7

2-mercapto-5-nitrobenzo[d]oxazole

Conditions
ConditionsYield
With hydrogenchloride In ethanol97%
In ethanol for 12h; Reflux;97%
In methanol for 6h; Reflux;94%
2,2'-dipyridyl carbonate
1659-31-0

2,2'-dipyridyl carbonate

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

5-nitro-3H-benzooxazol-2-one
3889-13-2

5-nitro-3H-benzooxazol-2-one

Conditions
ConditionsYield
In dichloromethane for 1h; Ambient temperature;96%
tris(tert-butylthio)cyclopropenylium perchlorate

tris(tert-butylthio)cyclopropenylium perchlorate

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

(Z)-2-<1',2',-bis(tert-butylthio)vinyl>-5-nitrobenzoxazole
124552-85-8

(Z)-2-<1',2',-bis(tert-butylthio)vinyl>-5-nitrobenzoxazole

Conditions
ConditionsYield
In methanol for 2h; Ambient temperature;96%
benzoyl chloride
98-88-4

benzoyl chloride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

5-nitro-2-phenylbenzo[d]oxazole
891-43-0

5-nitro-2-phenylbenzo[d]oxazole

Conditions
ConditionsYield
With Al-Cu-Cl- hydrotalcite at 60℃; for 1h;96%
Heating;94%
In 1,4-dioxane at 210℃; for 0.25h; microwave;90%
acetic anhydride
108-24-7

acetic anhydride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2-methyl-5-nitro-1,3-benzoxazole
32046-51-8

2-methyl-5-nitro-1,3-benzoxazole

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 100℃; Acetylation; cyclization;96%
With toluene-4-sulfonic acid In toluene at 50 - 120℃; for 3h;
Stage #1: acetic anhydride; 2-hydroxy-5-nitroaniline In toluene for 1h; Reflux;
Stage #2: With toluene-4-sulfonic acid In toluene for 5h; Dean-Stark;
8 g
2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

S-tert-butyl cyclohexylcarbamoylthioacetate
339274-36-1

S-tert-butyl cyclohexylcarbamoylthioacetate

N-cyclohexyl-malonamic acid 2-(2-cyclohexylcarbamoyl-acetylamino)-4-nitro-phenyl ester

N-cyclohexyl-malonamic acid 2-(2-cyclohexylcarbamoyl-acetylamino)-4-nitro-phenyl ester

Conditions
ConditionsYield
With silver trifluoroacetate In tetrahydrofuran at 20℃;96%
2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2,4-Dihydroxybenzaldehyde
95-01-2

2,4-Dihydroxybenzaldehyde

4-{(E)-[(2-hydroxy-5-nitrophenyl)imino]methyl}benzene-1,3-diol

4-{(E)-[(2-hydroxy-5-nitrophenyl)imino]methyl}benzene-1,3-diol

Conditions
ConditionsYield
In methanol at 20℃;96%
oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

5-nitrobenzo[d]oxazole-2-carboxylic acid ethyl ester

5-nitrobenzo[d]oxazole-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With sodium docusate In water at 60℃; for 2.5h; Reagent/catalyst;96%
acetic anhydride
108-24-7

acetic anhydride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2-acetamido-4-nitrophenol
97-60-9

2-acetamido-4-nitrophenol

Conditions
ConditionsYield
In water at 60℃;95%
With toluene-4-sulfonic acid In toluene at 100℃;82%
for 0.00277778h; Green chemistry;56%
With acetic acid
at 25℃;
potassium ethyl xanthogenate
140-89-6

potassium ethyl xanthogenate

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

4-nitro-1,3-benzoaxazolidine-2-thione
22876-21-7

4-nitro-1,3-benzoaxazolidine-2-thione

Conditions
ConditionsYield
With acetic acid In ethanol for 4.5h; pH=5; Reflux;95%
In ethanol Reflux;95%
In pyridine at 120℃; for 16h;84%
Stage #1: potassium ethyl xanthogenate; 2-hydroxy-5-nitroaniline In pyridine for 1h; Heating / reflux;
Stage #2: With hydrogenchloride In pyridine; water
79%
butyryl chloride
141-75-3

butyryl chloride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2-butyrylamino-4-nitrophenylbutanoate
477559-71-0

2-butyrylamino-4-nitrophenylbutanoate

Conditions
ConditionsYield
With triethanolamine In CH2C2; dichloromethane95%
orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

5-nitro-benzooxazole
70886-33-8

5-nitro-benzooxazole

Conditions
ConditionsYield
at 160℃; for 4h;95%
With 1,1'-((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(3-propyl-1H-imidazol-3-ium) bromide In neat (no solvent) for 0.333333h; Heating;92%
at 150℃; for 6h;85%
titanium(IV) isopropylate
546-68-9

titanium(IV) isopropylate

salicylaldehyde
90-02-8

salicylaldehyde

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

Ti(C6H3(NO2)(O)NCHC6H4(O))2
104453-12-5

Ti(C6H3(NO2)(O)NCHC6H4(O))2

Conditions
ConditionsYield
byproducts: (CH3)2CHOH, H2O; extn. (THF); elem. anal.;94.4%
(Z)-2-hydroxy-4-oxo-4-phenylbut-2-enoic acid
103344-70-3

(Z)-2-hydroxy-4-oxo-4-phenylbut-2-enoic acid

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

(Z)-6-nitro-3-(2-oxo-2-phenylethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-one

(Z)-6-nitro-3-(2-oxo-2-phenylethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-one

Conditions
ConditionsYield
In isopropyl alcohol for 2.5h; Heating;94%
4-chlorobenzoyl chloride
586-75-4

4-chlorobenzoyl chloride

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

2-(4-bromophenyl)-5-nitro-1,3-benzoxazole
112606-72-1

2-(4-bromophenyl)-5-nitro-1,3-benzoxazole

Conditions
ConditionsYield
In 1,4-dioxane at 210℃; for 0.25h; microwave;94%
Stage #1: 4-chlorobenzoyl chloride; 2-hydroxy-5-nitroaniline In 1,4-dioxane at 210℃; for 0.25h; Irradiation;
Stage #2: With sodium hydroxide In 1,4-dioxane; water at 20℃;
benzaldehyde
100-52-7

benzaldehyde

2-hydroxy-5-nitroaniline
99-57-0

2-hydroxy-5-nitroaniline

5-nitro-2-phenylbenzo[d]oxazole
891-43-0

5-nitro-2-phenylbenzo[d]oxazole

Conditions
ConditionsYield
With tin dioxide In ethanol at 20℃; for 0.216667h; Green chemistry;94%
In neat (no solvent) at 140℃; for 6h;90%
Stage #1: benzaldehyde; 2-hydroxy-5-nitroaniline In m-xylene at 120℃; for 0.5h; Inert atmosphere;
Stage #2: With oxygen; 4-methoxy-2,2,6,6-tetramethylpiperidin-1-oxyl radical In m-xylene at 120℃; for 10h;
89%
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