1,3-Diaminopropane supplier

Name
1,3-Diaminopropane
EINECS 203-702-7
CAS No. 109-76-2
Article Data86
CAS DataBase
Density 0.867 g/cm³
Solubility SOLUBLE
Melting Point -12 °C
Formula C₃H₁₀N₂
Boiling Point 135.5 °C at 760 mmHg
Molecular Weight 74.1258
Flash Point 48.9 °C
Transport Information UN 2922 8/PG 2
Appearance colourless liquid
Safety 26-36/37/39-45-25-16
Risk Codes 10-22-24-35
Molecular Structure
Hazard Symbols T,C
Synonyms 1,3-Diamino-n-propane;1,3-Propylenediamine;1,3-Trimethylenediamine;3-Aminopropylamine;DAP;NSC 8154;Trimethylenediamine;a,w-Propanediamine;1,3-Propanediamine;
PSA 52.04000
LogP 0.69450

Synthetic route

: 156-87-6
propan-1-ol-3-amine

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
	95%
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 135℃; under 26402.6 Torr; for 12h; Autoclave; Inert atmosphere;
With chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II); ammonia In toluene at 135℃; under 26402.6 Torr; for 12h; Autoclave; Inert atmosphere;

: C19H26N2O2

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With hydrogen; acetic acid In methanol	89%

: 4870-73-9
2,2-dimethyl-1,1-bis(2-cyanoethyl)hydrazine

A: 35513-93-0
N1-(cyanoethyl)-1,3-propanediamine

B: 22157-84-2
1,1-dimethyl-2-(3-aminopropyl)hydrazine

C: 109-76-2
Trimethylenediamine

D: 84714-27-2
2,2-dimethyl-1,1-bis(3-aminopropyl)hydrazine

Conditions

Conditions	Yield
With hydrogen; nickel In ethanol Catalytic hydrogenation; Further byproducts given;	A n/a B n/a C n/a D 66.2%

...Expand

: C12H28CrN5O(2+)

A: 4916-58-9
1,2-di-(3-pyridyl)-ethane

B: 108-99-6
3-Methylpyridine

C: 14873-01-9
chromium(III) hexahydrate cation

D: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
In perchloric acid Kinetics; (N2); decompn. of Cr complex in 1 M HClO4 depending on temp. under anaerobic conditions; not isolated, monitored by UV;	A 20% B 65% C n/a D n/a
In perchloric acid Kinetics; decompn. of Cr complex in 1 M HClO4 depending on temp. under aerobic conditions; not isolated, monitored by UV;	A 38% B 11% C n/a D n/a

...Expand

: 110-94-1
1,5-pentanedioic acid

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With chloroform; tris-(2-chloro-ethyl)-amine; sulfuric acid at 45℃;

: 151-18-8
2-cyanoethylamine

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With sodium-potassium alloy; butan-1-ol
With ammonia; hydrogen; nickel at 90℃; under 88260.9 Torr;

: 88192-19-2
3-azidopropylamine

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With hydrogenchloride im CO2-Strom;
With hydrogenchloride; tin(ll) chloride

: 3424-60-0
pentanediamide

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With potassium hypobromite at 0 - 60℃;

: 18664-94-3
butanediol bis-(propionitrile)ether

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With ammonia; water; nickel at 100℃; Hydrogenation.unter Druck;

: 64624-44-8
pentanedioyl azide

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With hydrogenchloride; ethanol at 100 - 110℃;

: 142-28-9
1,3-Dichloropropane

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With ethanol; ammonia; water

: 109-64-8
1,3-dibromo-propane

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With ethanol; ammonia anschl. mit wss. NaOH, dann mit HCl, anschl. mit KOH;
With ethanol; ammonia at 100℃; im Autoklaven;

: 57-13-6
urea

: 107-02-8
acrolein

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With sodium hydroxide; water; nitric acid at 150℃; under 51485.6 - 73550.8 Torr; Hydrogenation.an Raney-Nickel, anschl. Erwaermen mit NaOH;

: 107-02-8
acrolein

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With ammonia; nickel Hydrogenation.unter Druck;
With methanol; ammonia; water; hydrogen; nickel at 125℃; under 41188.4 - 61782.7 Torr;
With methanol; ammonia; water; hydrogen; nickel at 125℃; under 41188.4 - 61782.7 Torr;

: 503-29-7
azetidine

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With ammonia at 120℃; Rate constant; Mechanism; Thermodynamic data; ΔH(excit.), ΔS(excit.);;
With ammonium hydroxide; perchloric acid at 25℃; Rate constant; Thermodynamic data; E(a), ΔS(excit.);

: 14753-26-5
3-chloropropan-1-amine

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With ammonium hydroxide at 50℃; Rate constant; Thermodynamic data; E(a);

: 71-44-3
Spermine

A: 124-20-9
N-(3-aminopropyl)-1,4-diaminobutane

B: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With pyrroloquinoline quinone In water at 37℃; examination of PQQ oxidation effect; phosphate buffer (pH=7.2);

: 7688-51-9
N,N-bis(trimethylsilyl)allylamine

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With sodium hypochlorite; dimethylborane; ammonia 1.) 0 deg C, 1 h, 2.) O deg C; Yield given. Multistep reaction;

: 17400-34-9
(3-aminopropyl)carbamic acid benzyl ester hydrochloride

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol for 4h; Yield given;

: 121511-51-1
N-[1-(4-Hexadecyloxy-phenyl)-meth-(E)-ylidene]-N'-[1-(4-hexadecyloxy-phenyl)-meth-(Z)-ylidene]-propane-1,3-diamine

A: 59117-18-9
p-n-hexadecyloxybenzaldehyde

B: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With hydrogenchloride; water; cetyltrimethylammonim bromide In chloroform at 25℃; Rate constant;

: 124-20-9
N-(3-aminopropyl)-1,4-diaminobutane

A: 123-38-6
propionaldehyde

B: 109-76-2
Trimethylenediamine

C: 110-60-1
1,4-diaminobutane

Conditions

Conditions	Yield
With NaPi buffer; oxygen at 37℃; for 0.166667h; catalase and polyamine oxidase presence, pH 6.5, other polyamines and acetylpolyamines, kinetic constants Km (μM) and Vmax (μmol H2O2 formed μg protein-1 min-1);

...Expand

: 71-44-3
Spermine

A: 124-20-9
N-(3-aminopropyl)-1,4-diaminobutane

B: 123-38-6
propionaldehyde

C: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With NaPi buffer; oxygen at 37℃; for 0.166667h; catalase and polyamine oxidase presence, pH 6.5, other polyamines and acetylpolyamines, kinetic constants Km (μM) and Vmax (μmol H2O2 formed μg protein-1 min-1);

...Expand

: 13431-24-8
N8-Acetyl-Spermidine

A: 24431-54-7
4-(acetylamino)butanal

B: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With NaPi buffer; oxygen at 37℃; for 0.166667h; catalase and polyamine oxidase presence, pH 6.5, other polyamines and acetylpolyamines, kinetic constants Km (μM) and Vmax (μmol H2O2 formed μg protein-1 min-1);

: 14278-49-0
N1-Acetyl-Spermidine

: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With NaPi buffer; oxygen at 37℃; for 0.166667h; catalase and polyamine oxidase presence, pH 6.5, other polyamines and acetylpolyamines, kinetic constants Km (μM) and Vmax (μmol H2O2 formed μg protein-1 min-1);

: 25593-72-0
N1-acetylspermine

A: 109-76-2
Trimethylenediamine

B: N-(3-acetamidopropyl)-4-aminobutanal

Conditions

Conditions	Yield
With KPi buffer; oxygen at 37℃; for 0.166667h; catalase and polyamine oxidase presence, both bound or not bound to hydroxyapatite, other reagent: NaPi buffer, pH 6 or 6.5, other polyamines and acetylpolyamines, kinetic constants Km (μM) and Vmax (μmol H2O2 formed μg protein-1 min-1);

: 504-63-2
trimethyleneglycol

A: 109-76-2
Trimethylenediamine

B: 156-87-6
propan-1-ol-3-amine

Conditions

Conditions	Yield
With ammonia; hydrogen; Co-Fe catalyst at 195℃; under 37503 - 112509 Torr; Product distribution;
With ammonia; hydrogen; cobalt; iron at 195℃; under 101258 Torr; amination;
With ammonia; hydrogen; Co-La at 190℃; under 101258 Torr; amination;

: 504-63-2
trimethyleneglycol

A: 56-18-8
bis(3-aminopropyl)amine

B: 71-23-8
propan-1-ol

C: 109-76-2
Trimethylenediamine

D: 156-87-6
propan-1-ol-3-amine

Conditions

Conditions	Yield
With ammonia; hydrogen; carbon monoxide at 210℃; under 101258 Torr; Product distribution; Further Variations:; Catalysts; Temperatures; Pressures; amination;

...Expand

: 10132-25-9
2-(ethylsulfanyl)pyrimidine

: 64-17-5
ethanol

sodium: sodium

: 109-76-2
Trimethylenediamine

...Expand

: 82153-69-3
5-ethoxy-2-ethylmercapto-3H-pyrimidin-4-one

: 64-17-5
ethanol

sodium: sodium

: 109-76-2
Trimethylenediamine

...Expand

spermine: spermine

A: 37632-58-9
3-(2,5-dihydro-pyrrol-1-yl)-propylamine

B: 109-76-2
Trimethylenediamine

Conditions

Conditions	Yield
With sodium hydroxide; air; copper

: 109-76-2
Trimethylenediamine

: 98-59-9
p-toluenesulfonyl chloride

: 53364-99-1
N,N'-ditoluenesulfonyl-1,3-diaminopropane

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran; water at 0.2℃; for 3h; Inert atmosphere;	100%
at 80℃; for 0.5h;	95%
With potassium carbonate In tetrahydrofuran; water at 23℃; for 10h;	95%

: 605-65-2
5-(dimethylamino)naphth-1-ylsulfonyl chloride

: 109-76-2
Trimethylenediamine

: 34987-20-7
N-(3-aminopropyl)-5-(dimethylamino)naphthalene-1-sulfonamide

Conditions

Conditions	Yield
In dichloromethane at 0℃; for 4h;	100%
In dichloromethane at 20℃; for 18h; Inert atmosphere;	99%
In dichloromethane at 0 - 20℃; for 1h;	88%

: 109-76-2
Trimethylenediamine

: 107-13-1
acrylonitrile

: 35514-00-2
N1,N3-bis(2-cyanoethyl)propane-1,3-diamine

Conditions

Conditions	Yield
In methanol at 20℃; for 16h; Addition; cyanoethylation;	100%
at 0℃; for 24h; Darkness;	95%
In ethanol at 20℃; for 16h; Addition; cyanoethylation;	88%

: 109-76-2
Trimethylenediamine

: 93-91-4
1-phenylbutan-1,3-dione

: 74141-38-1
(Z)-3-{3-[(Z)-1-methyl-3-oxo-3-phenyl-1-propenylamino]propylamino}-1-phenyl-2-buten-1-one

Conditions

Conditions	Yield
With silica-supported ferric hydrogensulfate/[Fe(HSO4)3*SiO2] In neat (no solvent) at 20℃; for 0.266667h; regioselective reaction;	100%
In ethanol Heating;

: 98-03-3
thiophene-2-carbaldehyde

: 109-76-2
Trimethylenediamine

: bis-(2-thenylidene)-trimethylenediamine

Conditions

Conditions	Yield
In ethanol at 20℃; for 4h; Reflux;	100%
In ethanol for 1h; Heating;	69%
In benzene for 24h; Ambient temperature;

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 109-76-2
Trimethylenediamine

: 126556-34-1
N,N'-bis-(3,4,5-trimethoxybenzylidene)-1,3-diaminopropane

Conditions

Conditions	Yield
In methanol for 1h; Ambient temperature;	100%
In ethanol for 1h; Heating;	59%
In methanol at 20℃;

: 123-11-5
4-methoxy-benzaldehyde

: 109-76-2
Trimethylenediamine

: 6958-31-2
N,N′-bis[(4-methoxyphenyl)methlylidene]propane-1,3-diamine

Conditions

Conditions	Yield
In ethanol at 20℃; for 4h; Reflux;	100%
In ethanol at 20℃; for 4h;	96.2%
In methanol for 2h; Reflux;	90%

: 90-02-8
salicylaldehyde

: 109-76-2
Trimethylenediamine

: 120-70-7
N,N'-propane-1,3-diylbis(salicylideneimine)

Conditions

Conditions	Yield
In ethanol at 20℃; for 4h; Reflux;	100%
In methanol at 20℃; for 0.5h;	97%
In ethanol	97%

: 24424-99-5
di-tert-butyl dicarbonate

: 109-76-2
Trimethylenediamine

: 75178-96-0
N-Boc-1,3-diaminopropane

Conditions

Conditions	Yield
In chloroform 1.) 3 h, ice bath, 2.) room temperature, 16 h;	100%
In dichloromethane at 0 - 20℃; for 3h; Inert atmosphere;	100%
In 1,4-dioxane for 20h; Ambient temperature;	98%

: 7310-95-4
2-Hydroxy-5-methylisophthalaldehyde

: 109-76-2
Trimethylenediamine

: 37512-34-8
N,N'-propylenebis(3-formyl-5-methylsalicylaldimine)

Conditions

Conditions	Yield
	100%
In isopropyl alcohol at 20℃; for 1h;	47%
In ethanol Heating;

: 109-76-2
Trimethylenediamine

: 13089-45-7
8-bromo-2',3'-O-isopropylene adenosine

: 87888-81-1
{(3aR,4R,6R,6aR)-6-[6-Amino-8-(3-amino-propylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-methanol

Conditions

Conditions	Yield
In water at 120℃;	100%

: 109-76-2
Trimethylenediamine

: 67-64-1
acetone

: 104518-69-6
6,6-dimethyl-1,5-diazabicyclo<3.1.0>hexane

Conditions

Conditions	Yield
With sodium hypochlorite In water at -5 - 20℃; for 13h;	100%
With sodium hydroxide; sodium hypochlorite In water at 20℃; for 6h;	80%
With sodium hypochlorite In water at 0 - 5℃;
With tert-butylhypochlorite In methanol at -5 - 5℃; for 24h;

: 109-76-2
Trimethylenediamine

: 105-56-6
ethyl 2-cyanoacetate

: 111233-69-3
2-cyano-N-[3-(2-cyanoacetylamino)propyl]acetamide

Conditions

Conditions	Yield
	100%
for 24h; Ambient temperature;	90%
at 20℃; for 1h;	88%

: 109-76-2
Trimethylenediamine

: 6,7-Dimethoxy-naphthalene-2-carboxylic acid pentafluorophenyl ester

: 1,3-bis(6,7-dimethoxy-2-naphthalenecarboxamido)propane

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 70℃;	100%

: 80271-19-8
11-chloro-10H-indolo-[3,2-b]quinoline

: 109-76-2
Trimethylenediamine

: 188630-48-0
N1-(10H-indolo[3,2-b]quinolin-11-yl)propane-1,3-diamine

Conditions

Conditions	Yield
With hydrogenchloride In 2-ethoxy-ethanol for 15h; Heating;	100%
Stage #1: 11-chloro-10H-indolo-[3,2-b]quinoline; Trimethylenediamine With hydrogenchloride In 2-ethoxy-ethanol; water for 17h; Reflux; Stage #2: With potassium hydroxide In 2-ethoxy-ethanol; water Cooling with ice;	75.7%

: 37031-29-1
(-)-dimethy-2,3-O-isopropylidene-L-tartrate

: 109-76-2
Trimethylenediamine

: 197906-38-0
(4R,5R)-2,2-Dimethyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-[(3-amino-propyl)-amide]

Conditions

Conditions	Yield
In methanol for 216h; Ambient temperature;	100%

: 57280-22-5
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

: 109-76-2
Trimethylenediamine

: C17H34N2O6

Conditions

Conditions	Yield
In ethanol epoxide:amine=2:1;	100%

: 109-76-2
Trimethylenediamine

: 133628-17-8
(2S,4R)-4-(methanesulfonyloxy)-2-[(methanesulfonyloxy)methyl]pyrrolidine-1-carboxylic acid tert-butyl ester

: 191280-84-9
(1S,4S)-5-(3-aminopropyl)-2-(tert-butoxycarbonyl)-2,5-diazabicyclo[2.2.1]heptane

Conditions

Conditions	Yield
4 h, 60 deg C, 8 h;	100%

: 37031-29-1, 6134-82-3, 6135-80-4, 90613-41-5, 116499-08-2, 37031-30-4
(+)-dimethyl-2,3-O-isopropylidene-D-tartrate

: 109-76-2
Trimethylenediamine

: (4S,5S)-2,2-Dimethyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-[(3-amino-propyl)-amide]

Conditions

Conditions	Yield
at 20℃; for 5.5h; Acylation;	100%
at 20℃; for 5.5h;

: 86-98-6
4,7-dichloroquinoline

: 109-76-2
Trimethylenediamine

: 7597-14-0
N-(7-chloroquinolin-4-yl)propane-1,3-diamine

Conditions

Conditions	Yield
In neat (no solvent) at 110℃;	100%
Inert atmosphere;	100%
In isopropyl alcohol at 100℃; for 20h;	98%

: 108545-38-6
5-hexynoic acid ethyl ester

: 109-76-2
Trimethylenediamine

: 398507-42-1
N-(3-aminopropyl)hex-5-ynamide

Conditions

Conditions	Yield
at 60℃; for 48h;	100%

: 73111-64-5
(3aS,4S,6R,6aS)-2,2-dimethyl-6-vinyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol

: 109-76-2
Trimethylenediamine

: hexahydro-2-[[D-lyxo-3-hydroxy-1,2-[(1-methylethylidene)bis(oxy)]-4-pentenyl]]pyrimidine

Conditions

Conditions	Yield
	100%

: 109-76-2
Trimethylenediamine

: 3β-(4'-chlorophenyl)tropane-2β-carboxylic acid

: 1,3-di-(3β-(p-chlorophenyl)tropane-2β-carboxamide)-propane

Conditions

Conditions	Yield
Stage #1: 3β-(4'-chlorophenyl)tropane-2β-carboxylic acid With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In dichloromethane at 0℃; for 0.166667h; Stage #2: Trimethylenediamine In dichloromethane at 20℃;	100%

: 109-76-2
Trimethylenediamine

N-carboxyethylchitin ethyl ester; Mn=12000, Mw=49000, degree of CO2Et substitution per sugar unit =1.17: N-carboxyethylchitin ethyl ester; Mn=12000, Mw=49000, degree of CO2Et substitution per sugar unit =1.17

N-carboxyethylchitin 3-aminopropylamide: N-carboxyethylchitin 3-aminopropylamide

Conditions

Conditions	Yield
In ethanol; water at 70℃; for 24h;	100%

: 105-45-3
acetoacetic acid methyl ester

: 109-76-2
Trimethylenediamine

: 3-[3-(2-methoxycarbonyl-1-methylvinylamino)-propylamino]but-2-enoic acid methyl ester

Conditions

Conditions	Yield
With silica-supported ferric hydrogensulfate/[Fe(HSO4)3*SiO2] In neat (no solvent) at 20℃; for 0.2h; regioselective reaction;	100%
zirconium(IV) chloride at 20℃; for 0.25h;	95%
With sulfated zirconia at 20℃; for 0.416667h;	92%

: 874306-28-2
(3α,5β)-3,24-bis(3-bromophenoxy)cholane

: 109-76-2
Trimethylenediamine

: 874306-46-4
N1-[3-((R)-4-{(3S,5R,8R,9S,10S,13R,14S,17R)-3-[3-(3-Amino-propylamino)-phenoxy]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentyloxy)-phenyl]-propane-1,3-diamine

Conditions

Conditions	Yield
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; bis(dibenzylideneacetone)-palladium(0) In 1,4-dioxane Heating;	100%
With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; [Pd(dibenzylideneacetone)2] In 1,4-dioxane for 5h; Heating;	60 % Spectr.

: 109-76-2
Trimethylenediamine

: 642-31-9
9-anthracene aldehyde

: N-((anthracen-10-Yl)methylene)-N′-((anthracen-9-Yl)methylene)propane-1,3-diamine

Conditions

Conditions	Yield
With acetic acid In ethanol Heating;	100%
In methanol; N,N-dimethyl-formamide for 4h; Heating;	94%
With acetic acid In methanol for 12h; Reflux;	85.32%

: 251349-29-8
C18H33O2N

: 109-76-2
Trimethylenediamine

: 1026288-30-1
C20H39ON3

Conditions

Conditions	Yield
In methanol at 20℃; for 120h;	100%

: C18H33NO2

: 109-76-2
Trimethylenediamine

: C20H39N3O

Conditions

Conditions	Yield
In methanol at 20℃; for 72h;	100%

: 7440-32-6
titanium

: 86119-84-8, 7664-38-2
phosphoric acid

: 7732-18-5
water

: 109-76-2
Trimethylenediamine

: Ti2(PO4)(HPO4)2*(water)2*0.5(1,3-diaminopropane)

Conditions

Conditions	Yield
In neat (no solvent) Ti:1,3-diaminopropane:H3PO4:H2O ratio = 2:2.21:13.65:500, autoclave, pH=2, 170°C (1 d, autogenous pressure); washing (water, alcohol and acetone); elem. anal.;	100%
With boric acid; HF In neat (no solvent) Ti:boric acid:H3PO4:1,3-diaminopropane:HF:H2O ratio = 1:6.54:13.65:2.21:3.36:600;

...Expand

1,3-Diaminopropane Consensus Reports

Reported in EPA TSCA Inventory.

1,3-Diaminopropane Specification

The 1,3-Diaminopropane is an organic compound with the formula C₃H₁₀N₂. The IUPAC name of this chemical is propane-1,3-diamine. With the CAS registry number 109-76-2, it is also named as 1,3-Diamino-n-propane. The product's categories are Amines; alpha,omega-Alkanediamines; alpha,omega-Bifunctional Alkanes; Monofunctional & alpha,omega-Bifunctional Alkanes. Besides, it is a colourless liquid, which should be stored in a cool dry and ventilated place. It can be used not only for medicine, pesticide synthesis, auxiliary materials of paper making, textile and leather industries, but also for the synthesis of epoxy curing agent.

Physical properties about 1,3-Diaminopropane are: (1)ACD/LogP: -1.42; (2)ACD/LogD (pH 5.5): -5.52; (3)ACD/LogD (pH 7.4): -5.15; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 2; (9)#H bond donors: 4; (10)#Freely Rotating Bonds: 4; (11)Polar Surface Area: 6.48 Å²; (12)Index of Refraction: 1.451; (13)Molar Refractivity: 23.01 cm³; (14)Molar Volume: 85.4 cm³; (15)Polarizability: 9.12×10^-24cm³; (16)Surface Tension: 36.2 dyne/cm; (17)Density: 0.867 g/cm³; (18)Flash Point: 48.9 °C; (19)Enthalpy of Vaporization: 40.85 kJ/mol; (20)Boiling Point: 135.5 °C at 760 mmHg; (21)Vapour Pressure: 7.7 mmHg at 25°C.

Preparation: this chemical can be prepared by dibromopropane and saturated ammonia and ethanol.

Uses of 1,3-Diaminopropane: it can be used to produce 1,5-diaza-bicyclo[3.1.0]hexane at temperature of 0 °C. It will need reagent aq. HCl and NaOCl with reaction time of 24 hours.

When you are using this chemical, please be cautious about it as the following:
It is flammable and harmful if swallowed. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical can cause severe burns. When you are using it, wear suitable gloves and eye/face protection, keep away from sources of ignition - No smoking and avoid contact with eyes In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: NCCCN
(2)InChI: InChI=1/C3H10N2/c4-2-1-3-5/h1-5H2
(3)InChIKey: XFNJVJPLKCPIBV-UHFFFAOYAG
(4)Std. InChI: InChI=1S/C3H10N2/c4-2-1-3-5/h1-5H2
(5)Std. InChIKey: XFNJVJPLKCPIBV-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	296mg/kg (296mg/kg)	Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
rabbit	LD50	skin	200uL/kg (0.2mL/kg)	American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962.
rat	LD50	oral	350uL/kg (0.35mL/kg)	American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962.

Product Name

1,3-Diaminopropane

Synthetic route

1,3-Diaminopropane Consensus Reports

1,3-Diaminopropane Specification

Related Products

Hot Products